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license: apache-2.0 |
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tags: |
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- biology |
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size_categories: |
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- 1B<n<10B |
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# Dataset Card for GuideRNA-3B |
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## Dataset Description |
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- **Homepage:** https://github.com/bm2-lab/CRISPR-viva |
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- **Repository:** https://github.com/bm2-lab/CRISPR-viva |
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- **Contact:** [email protected] |
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### Dataset Summary |
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**GuideRNA-3B** is a large transcriptome sequence corpus consisting of over 3.7 billion paired sequences extracted from the specific transcriptome of 23 cell lines and over 200 segmented genomes of RNA virus. |
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### Supported Tasks |
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Based on this nucleotide sequence corpus, we are able to establish a foundation model to characterize the manifold of CRISPR guide RNA targeting regions in order to undertake further downstreaming task for universal CRISPR-based RNA virus amplification-free detection and inhibition. |
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For details, please refer to [our paper](https://github.com/bm2-lab/CRISPR-viva) and [website](https://github.com/bm2-lab/CRISPR-viva). |
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### Languages |
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English (en). |
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## Dataset Structure |
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### jsonl-based Arrow |
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These files are compressed Arrow-formated sourced from JSON-lined text file data, with the following columns: |
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- `before`: string. Nucleotide sequence from transcriptome of cell line or RNA virus. |
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- `next`: string. Nucleotide sequence with postion right-shifted by one. |
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### Citation Information |
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If you find **GuideRNA-3B** helpful in your research, please cite our work by: |
