Analysis of serial electroencephalographic predictors of seizure recurrence in Rolandic epilepsy.
PURPOSE
We aimed to assess the relationship between electroencephalography (EEG) markers and seizure recurrence in cases with benign epilepsy with centrotemporal spikes (BECT) in a long-term follow-up study.


METHODS
We analyzed the data of 52 children with BECT who were divided into 2 groups: the isolated group and recurrence group. The clinical profiles and initial/serial visual EEG recordings of both groups were evaluated. The entire follow-up period ranged from 12 to 65 months.


RESULTS
None of the clinical characteristics differed between the 2 groups. Serial EEGs showed that the appearance of Rolandic spikes in the frontal region was more prevalent in the recurrence group. Moreover, a significant correlation was found between bilateral asynchronous discharges and seizure recurrence. However, on initial EEG of these patients, neither of the EEG features exhibited statistical significance.


CONCLUSION
The presence of frontal focus and bilateral asynchrony appeared to be hallmarks of BECT patients with higher risk for seizure recurrence.
['Tang|Hongwei|H|', 'Wang|Yanping|Y|', 'Hua|Ying|Y|', 'Wang|Jianbiao|J|', 'Jing|Miao|M|', 'Hu|Xiaoyue|X|0000-0001-8465-819X']
D002648:Child D002675:Child, Preschool D004569:Electroencephalography D019305:Epilepsy, Rolandic D005260:Female D005625:Frontal Lobe D006801:Humans D008297:Male D012008:Recurrence D012640:Seizures
Seizure Rolandic epilepsy EEG BECT