The contact Lens risk survey to assess risk of soft contact lens-related inflammatory events.
PURPOSE
To test the Contact Lens Assessment in Youth Contact Lens Risk Survey (CLRS) scoring algorithm in soft contact lens (SCL) wearers presenting with SCL-related adverse events and healthy matched controls.


METHODS
This prospective case-control study compared CLRS responses in SCL wearers presenting with symptomatic red eyes (Cases) with age-, sex- and site-matched healthy SCL wearers (Controls) at six locations across North America. Responses to individual questions from Cases and Controls were analyzed using either the Pearson, Mantel-Haenszel chi-square, or Fisher's exact test. Differences in the CLRS scores were compared using t-tests.


RESULTS
A total of 171 SCL wearers were enrolled (n = 57 Cases, 114 Controls). Cases were adjudicated to consensus and classified as contact lens-related serious and significant (S&S) or non-serious events. S&S Cases scored significantly higher on the CLRS (56.1 ± 11.1) than either their matched Controls (44.3 ± 11.1) (P <  0.001) or the non-Serious Cases (44.8± 12.8 P =  0.002). Scores of non-serious Cases were not significantly different than scores of their Controls (43.4 ± 10.7, P = 0.33) CONCLUSIONS: The CLRS scoring algorithm discriminated between SCL wearers presenting with S&S CL-related adverse events from healthy SCL wearers and those with non-serious events. This survey and scoring system could help practitioners identify patients at greatest risk for CL-related adverse events and support targeted interventions aimed at reducing risk behaviors.
['Mickles|Chandra V|CV|', 'Kinoshita|Beth T|BT|', 'Lam|Dawn|D|', 'Wagner|Heidi|H|', 'Zimmerman|Aaron B|AB|', 'Sorbara|Luigina|L|', 'Mitchell|G Lynn|GL|', 'Rosner|Bernard|B|', 'Richdale|Kathryn|K|']
D000293:Adolescent D016022:Case-Control Studies D003263:Contact Lenses, Hydrophilic D006801:Humans D012307:Risk Factors D012309:Risk-Taking D011795:Surveys and Questionnaires
Risk Survey Soft contact lens Adverse events