The influence of comorbidities on the aging males' symptoms scale in patients with erectile dysfunction.
OBJECTIVES
To investigate if certain common age-related comorbidities are related with a positive aging males' symptoms (AMS) test outcome.


METHODS
This was a multicentric, transversal, observational study carried out in a male population with erectile dysfunction. Comorbidities and testosterone levels were registered. The relationship between comorbidities, testosterone levels, and the AMS test outcomes was studied using the global score and the sub-scale score components.


RESULTS
The study included 1112 patients. In the multivariate analysis the global score strongly correlated with TT < 12 nmol/L (odds ratio [OR] = 3.17; p < 0.05), psychiatric disorders (OR = 2.73), dyslipidemia (OR = 2.07) and diabetes mellitus (OR = 1.64); the somatic sub-component was related to obesity (OR = 8.62), dyslipidemia (OR = 2.2) and TT < 12 nmol/L (OR = 2.09); the psychogenic sub-component correlated with psychiatric disorders (OR = 3.73), stress (OR = 2.42), dyslipidemia (OR = 1.78) and TT < 12 nmol/L (OR = 1.77); and the sexual sub-component was associated with high blood pressure (OR = 2.94).


CONCLUSION
Although the AMS test is related to low levels of testosterone, it is also of some limited use for diagnosing hypogonadism because it has low specificity and is influenced by pathologies that are frequent during ageing.
['Panach-Navarrete|Jorge|J|', 'Martínez-Jabaloyas|José María|JM|', '|||']
D000293:Adolescent D000328:Adult D000375:Aging D015897:Comorbidity D007172:Erectile Dysfunction D006801:Humans D007006:Hypogonadism D008297:Male D008875:Middle Aged D015995:Prevalence D012307:Risk Factors D012680:Sensitivity and Specificity D011795:Surveys and Questionnaires D013739:Testosterone D055815:Young Adult
Testosterone diabetes hypogonadism aging males’ symptoms scale androgen deficiency hypertension