The Role of Atrioventricular and Interventricular Optimization for Cardiac Resynchronization Therapy.
Many patients with left ventricular systolic dysfunction may benefit from cardiac resynchronization therapy; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. AV and VV delay optimization techniques have included echocardiography, device-based algorithms, and several other novel noninvasive techniques. Using these techniques to optimize device settings has been shown to improve hemodynamic function acutely; however, the long-term clinical benefit is limited. In most cases, an empiric AV delay with simultaneous biventricular or left ventricular pacing is adequate. The value of optimization of these intervals in "nonresponders" still requires further investigation.
['Cobb|Daniel B|DB|', 'Gold|Michael R|MR|']
D001283:Atrioventricular Node D058406:Cardiac Resynchronization Therapy D003936:Diagnosis, Computer-Assisted D004452:Echocardiography D004562:Electrocardiography D019317:Evidence-Based Medicine D006333:Heart Failure D006801:Humans D018579:Patient Selection D013813:Therapy, Computer-Assisted D016896:Treatment Outcome D018487:Ventricular Dysfunction, Left
Optimization Cardiac resynchronization therapy AV delay Heart failure Implantable defibrillator