Usefulness of PET/CT 18-FDG for the diagnosis and follow-up of urological, urothelial and kidney tumours.
INTRODUCTION
New imaging studies have appeared in recent years for the diagnosis and follow-up of metastatic urological tumours.


MATERIAL AND METHODS
A total of 41 patients were reviewed with suspected recurrence of a urothelial or kidney tumour, analysing the diagnostic performance of PET-CT scans undertaken between 2013 and 2016.


RESULTS
We collected 17 urothelial tumours and 24 renal tumours, with a median follow-up of 30 months. A total of 39.3% of the urothelial tumours were high grade and 29.3% of the kidney tumours were clear cell Fuhrman II. As a whole, the imaging studies detected recurrences in 34 patients. CT was positive in 83% of the patients, while the PET scan was positive in 75.6%, CT/PET coincidence was 50%. The PET scan detected further disease in 41% of the cases compared to 5% by CT. This resulted in a change of therapeutic strategy in 40% of the patients. Sensitivity, specificity, positive predictive value and negative predictive value for the CT and the PET scans were 92% and 92%, 57% and 100%, 92% and 100%, and 57% and 70% respectively.


CONCLUSION
The PET scan showed similar sensitivity for urological tumours to the standard imaging techniques but with higher specificity, positive predictive value and negative predictive value. This led to a change in treatment strategy for 40% of the patients in our series. The PET scan will probably become the standard test in the extension and follow-up studies of most urological tumours.
['González-Ruiz de León|C|C|', 'García-Rodríguez|J|J|', 'Pérez-Castro|N|N|', 'Vigil-Díaz|C|C|', 'Pérez-Haro|M L|ML|', 'Fernández-Gómez|J M|JM|']
D000328:Adult D000368:Aged D002291:Carcinoma, Papillary D002292:Carcinoma, Renal Cell D002295:Carcinoma, Transitional Cell D018291:Cystadenoma, Mucinous D005260:Female D005462:Fluorine Radioisotopes D019788:Fluorodeoxyglucose F18 D005500:Follow-Up Studies D006801:Humans D007680:Kidney Neoplasms D008113:Liver Neoplasms D008297:Male D008875:Middle Aged D009364:Neoplasm Recurrence, Local D000072078:Positron Emission Tomography Computed Tomography D049268:Positron-Emission Tomography D011237:Predictive Value of Tests D019275:Radiopharmaceuticals D012680:Sensitivity and Specificity D014057:Tomography, X-Ray Computed D001749:Urinary Bladder Neoplasms D014571:Urologic Neoplasms
PET/CT 18-FDG Urological Metastastatic Metastásico PET/TC 18-FDG Urológico