Root dentine demineralisation according to frequency of sucrose exposure using high-fluoride dentifrice.
OBJECTIVE
To evaluate root dentine demineralisation, biomass and loosely bound fluoride (CaF2 ) concentration according to different frequencies of sucrose exposure using a high-fluoride dentifrice.


BACKGROUND
Although high-fluoride dentifrice has been recommended to arrest root dentine lesions, it is not clear whether it can protect dentine from increased frequencies of sucrose exposure.


METHODS
An in situ, crossover, split-mouth study was conducted in 3 phases with 7 days each, in which 10 volunteers used a palatal device containing 4 bovine root dentine slabs (2 on each side) with predetermined initial hardness. Cariogenic challenge consisted in dripping a 20% sucrose solution 0 (control), 2, 4, 6, 8 or 10 times/d in each block. Volunteers used high-fluoride dentifrice (NaF, 5000 µg F/g) 3 times/d. After each phase, final hardness was measured and the percentage of surface hardness loss (%SHL) calculated. Also, biomass and CaF2 concentration on dentine were determined. The data were processed and analysed by ANOVA and Tukey test with significance level set at 5%. The relationship between the variables was analysed by linear regression and Pearson correlation (r).


RESULTS
%SHL and biomass were significantly greater than control for sucrose frequencies higher than 6 times/d (P < 0.001), while CaF2 concentration decreased from sucrose frequency higher than 2 times/d (P < 0.001). Regression analysis data showed a significant linear fit between sucrose exposure frequency and the studied variables with a strong correlation (r) for %SHL and CaF2 and moderate for biomass (P < 0.05).


CONCLUSION
High-fluoride dentifrice is able to reduce root dentine demineralisation if sucrose consumption is not higher than 6 times/d.
['Rolim|Fabiana|F|', 'Melo|Clésio|C|', 'Silva|Miquéias|M|', 'Tabchoury|Cinthia|C|', 'Vale|Glauber|G|https://orcid.org/0000-0002-6055-9493']
D000818:Animals D002327:Cariostatic Agents D002417:Cattle D018592:Cross-Over Studies D003802:Dentifrices D003804:Dentin D005459:Fluorides D006801:Humans D013395:Sucrose
root dentine demineralisation dentifrices fluoride