Chiral Calcium-Catalyzed Asymmetric Epoxidation Reactions Using Hydrogen Peroxide as the Terminal Oxidant.
Asymmetric epoxidation reactions of chalcone derivatives catalyzed by chiral calcium complexes using hydrogen peroxide were developed. The epoxidation reactions proceeded smoothly to afford the desired products in good yields with good enantioselectivities. This is the first example of chiral calcium-catalyzed asymmetric epoxidation reactions using hydrogen peroxide as the terminal oxidant.
['Yamashita|Yasuhiro|Y|', 'Macor|Joseph Alexander|JA|', 'Fushimi|Seiya|S|', 'Tsubogo|Tetsu|T|', 'Kobayashi|Shū|S|']
D002118:Calcium D002384:Catalysis D047188:Chalcones D056831:Coordination Complexes D004852:Epoxy Compounds D006861:Hydrogen Peroxide D015394:Molecular Structure D016877:Oxidants D010084:Oxidation-Reduction D013237:Stereoisomerism
asymmetric epoxidation hydrogen peroxide chiral calcium catalyst