Time for a paradigm shift in the use of plant genetic resources.
For all major crops, sizeable genebanks are maintained across the world and serve as repositories of genetic diversity and key sources of novel traits used in breeding. Although molecular markers have been used to characterize diversity in a broad sense, the most common approach to exploring these resources has been through phenotypic characterization of subsets of these large collections. With the advent of affordable large-scale genotyping technologies and the increasing body of candidate genes for traits of interest, we argue here that it is time for a paradigm shift in the way that we explore and exploit these considerable and highly useful resources. By combining dense genotypic information in and around candidate genes, it is possible to classify accessions based on their haplotype, something approximating the actual alleles at these genes of interest.
['Belzile|François|F|', 'Abed|Amina|A|', 'Torkamaneh|Davoud|D|']
D018556:Crops, Agricultural D030541:Databases, Genetic D014644:Genetic Variation D005838:Genotype D006239:Haplotypes D059014:High-Throughput Nucleotide Sequencing D017422:Sequence Analysis, DNA
plant genetic resources phenotyping analyse haplotypique haplotype analysis next-generation sequencing phénotypage ressources génétiques végétales séquençage de nouvelle génération