Development of a lateral flow immunoassay strip for rapid detection of CagA antigen of Helicobacter pylori.
About half of the world populations are known to be infected with Helicobacter pylori. The CagA antigen secreting strains provoke severe mucosal damages and act as a risk factor for the development of peptic ulceration and gastric cancer. A lateral flow immunoassay (LFIA) strip was developed based on sandwich format for rapid detection of CagA antigen of H. pylori using gold conjugated monoclonal antibody. This LFIA strip will provide a good aid in the diagnosis of CagA-secreting H. pylori within 10 min instead of time consuming, expensive and laborious invasive approaches.
['Karakus|Cebrail|C|']
D000818:Animals D058846:Antibodies, Monoclonal, Murine-Derived D000942:Antigens, Bacterial D001426:Bacterial Proteins D016481:Helicobacter Infections D016480:Helicobacter pylori D006801:Humans D007150:Immunohistochemistry D051379:Mice
lateral flow immunoassay strip CagA antigen Helicobacter pylori colloidal gold