Biocompatible chitosan-pectin polyelectrolyte complex for simultaneous electrochemical determination of metronidazole and metribuzin.
Development of novel biocompatible sensor material suitable for modest, cost-effective, and rapid practical application is a demanding research interest in the field of electroanalytical chemistry. In this context, for the first time, we utilized biocompatible chitosan-pectin biopolyelectrolyte (CS-PC BPE) complex for the simultaneous electroreduction of an important antibiotic drug (metronidazole-MNZ) and herbicide (metribuzin-MTZ). This sensor reveals an attractive welfares such as simplicity, biocompatibility, and low production cost. Under optimized experimental conditions, the electroanalytical investigation confirmed that CS-PC BPE modified glassy carbon electrode (CS-PC BPE/GCE) was found to sense MNZ and MTZ in the nanomolar range. Moreover, as-prepared CS-PC BPE/GCE exhibited prominent selectivity, stability, and reproducibility. Additionally, the possible MNZ and MTZ sensing mechanism of CS-PC BPE/GCE have been discussed in detail. Lastly, real sample analysis was also carried out and revealed from several investigations that the CS-PC BPE/GCE is a good electrochemical sensor system for the detection of targeted analytes.
['Ranganathan|Palraj|P|', 'Mutharani|Bhuvanenthiran|B|', 'Chen|Shen-Ming|SM|', 'Sireesha|Pedaballi|P|']
D000900:Anti-Bacterial Agents D001672:Biocompatible Materials D002244:Carbon D048271:Chitosan D055664:Electrochemical Techniques D004566:Electrodes D055772:Green Chemistry Technology D006540:Herbicides D006801:Humans D057230:Limit of Detection D008795:Metronidazole D008970:Molecular Weight D010084:Oxidation-Reduction D010368:Pectins D000071228:Polyelectrolytes D015203:Reproducibility of Results D014227:Triazines D014783:Viscosity
Metronidazole Metribuzin Biopolyelectrolyte Simultaneous determination