A mechanistic overview of herbal medicine and botanical compounds to target transcriptional factors in Breast cancer.
The abnormalities of transcription factors, such as NF-κB, STAT, estrogen receptor, play a critical role in the initiation and progression of breast cancer. Due to the limitation of current treatment, transcription factors could be promising therapeutic targets, which have received close attention. In this review, we introduced herbal medicines, as well as botanical compounds that had been verified with anti-tumor properties via regulating transcription factors. Herbs, compounds, as well as formulae reported with various transcriptional targets, were summarized thoroughly, to provide implication for the future research on basic experiment and clinical application.
['Zhao|Yingke|Y|', 'Liu|Yue|Y|']
D000818:Animals D001943:Breast Neoplasms D004365:Drugs, Chinese Herbal D005260:Female D006801:Humans D008517:Phytotherapy D010946:Plants, Medicinal D014157:Transcription Factors
Herbal medicine Botanical compounds Transcription factor Breast cancer