Normal karyotype in a case of acute myeloid leukemia with monocytic differentiation and hemophagocytosis by leukemic blasts.
We report the case of a 39-year-old woman with acute myeloid leukemia (AML) with monocytic differentiation showing hemophagocytosis by leukemic blasts. This phenomenon is known to be associated with certain chromosomal changes, including t(8;16), der(8), inv(8), and t(16;21); however, in this case, the patient had a normal female karyotype. To our knowledge, this is the first published case of normal karyotype AML with hemophagocytosis by leukemic blasts.
['Salazar|Katrina L|KL|', 'Mosse|Claudio|C|']
D000328:Adult D002454:Cell Differentiation D005260:Female D006801:Humans D059785:Karyotype D015470:Leukemia, Myeloid, Acute D051359:Lymphohistiocytosis, Hemophagocytic D009000:Monocytes
acute myeloid leukemia monocytic differentiation hemophagocytosis erythrophagocytosis leukophagocytosis t(8 16)