A case of immunoglobulin G4-related sclerosing mesenteritis without other organ involvement.
A 64-year-old man presented to our hospital with abdominal pain and 4-5 episodes of watery diarrhea per day for 2 months. Abdominal ultrasound examination revealed a mass in the peritoneal cavity, and computed tomography showed a 13.4 cm mass in the mesentery and a 3 cm mass in the mesocolon. The patient underwent laparoscopic partial resection for diagnosis. ﻿Microscopically, abundant fibrosis and numerous immunoglobulin (Ig) G4-positive plasma cells were observed. ﻿The serum level of IgG4 was 665 mg/dl postoperatively. ﻿These findings suggested that the lesion was consistent with IgG4-related sclerosing mesenteritis. Oral steroids resulted in rapid disappearance of symptoms and a decrease in masses. Recently, sclerosing mesenteritis are reported as IgG4-related disease or mimicking IgG4-related disease but multiple lesions rarely occur in the same organ. We report a case of IgG4-related sclerosing mesenteritis with multiple lesions without involvement of other organs, such as the pancreas and salivary glands.
['Kozono|Masaya|M|', 'Tanoue|Shiroh|S|http://orcid.org/0000-0003-2625-2698', 'Kiyama|Kanna|K|', 'Jikuya|Kenichi|K|', 'Kawahira|Machiko|M|', 'Hinokuchi|Makoto|M|', 'Iwaya|Hiromichi|H|', 'Arima|Shiho|S|', 'Hashimoto|Shinichi|S|', 'Hiwatashi|Kiyokazu|K|', 'Fukuda|Yoshio|Y|', 'Sakoda|Masahiko|M|', 'Higashi|Michiyo|M|', 'Tokushige|Koichi|K|', 'Ido|Akio|A|']
D006801:Humans D007074:Immunoglobulin G D000077733:Immunoglobulin G4-Related Disease D008297:Male D008643:Mesentery D008875:Middle Aged D015436:Panniculitis, Peritoneal D014463:Ultrasonography
Sclerosing mesenteritis Diarrhea IgG4-related disease