Enhanced biomimic bactericidal surfaces by coating with positively-charged ZIF nano-dagger arrays.
Cicada wing surfaces are covered with dense patterns of nano-pillar structure that prevent bacterial growth by rupturing adhered microbial cells. To mimic the natural nano-pillar structure, we developed a general and simple method to grow metal organic framework (MOF) nano-dagger arrays on a wide range of surfaces. These nano-daggers possess high bactericidal activity, with log reduction >7 for Escherichia coli and Staphylococcus aureus. It was hypothesized that the positively-charged ZIF-L nano-dagger surfaces enhance bacterial cell adhesion, facilitating selective and efficient bacteria killing by the rigid and sharp nano-dagger tips. This research provides a safe and clean antimicrobial surface technology which does not require external chemicals and will not cause drug resistance.
['Yuan|Yuan|Y|', 'Zhang|Yugen|Y|']
D000900:Anti-Bacterial Agents D001422:Bacterial Adhesion D001424:Bacterial Infections D040761:Biomimetic Materials D004926:Escherichia coli D006801:Humans D000073396:Metal-Organic Frameworks D049329:Nanostructures D013211:Staphylococcus aureus D013499:Surface Properties
Antimicrobial surface Cell rupturing Surface interaction ZIF coating