Preeclampsia and Related Cardiovascular Risk: Common Genetic Background.
PURPOSE OF REVIEW
Preeclampsia (PE) is a hypertensive disorder exclusive for pregnancy. It affects women all over the world and poses a great threat to life, both for mother and child. No definitive treatment exists and placenta delivery comprises the only known cure for PE. One of the most severe complications observed in preeclamptic women is the occurrence of cardiovascular diseases (CVDs) later in life.


RECENT FINDINGS
Both PE and CVDs share some of their pathogenic pathways and gene variations. Thus far, a number of publications have examined those relationships; however, almost all of them focus only on common risk factors. The precise pathomechanism and genetic basis of PE and its associated cardiovascular complications remain unknown. Therefore, the aim of this review is to unify and clarify the current state of knowledge and provide direction for future studies, especially those regarding the genetic aspect.
['Lisowska|Michalina|M|0000-0002-6127-4481', 'Pietrucha|Tadeusz|T|', 'Sakowicz|Agata|A|']
D002318:Cardiovascular Diseases D005260:Female D000068617:Genetic Background D006801:Humans D011225:Pre-Eclampsia D011247:Pregnancy D012307:Risk Factors
Preeclampsia Cardiovascular risk Genetics Pregnancy Cardiovascular disease Pre-eclampsia