Could 675-nm Laser Treatment Be Effective for Facial Melasma Even in Darker Phototype?
The study assesses the safety and efficacy of a 675-nm laser source on melasma.  Melasma is a frequent acquired skin disease defined by the presence of hyperpigmented macules on the face.  Study protocol included up to three sessions of the 675-nm laser. Objective evaluation was assessed by using a 5-point visual analogue pain scale (VAS) (range, 0-4). Treatment tolerance was assessed using the 5-point VAS.  A mean 3.1 ± 0.7 improvement was reached according to photographic evaluation by VAS. Patients treated one time showed mean clearance of 3.3 ± 0.76, patients treated two times showed mean clearance of 3.0 ± 0.71, and patients treated three times showed mean clearance of 3.0 ± 1. Pain score mean was 1.2 ± 0.4.  The 675-nm laser system seems to be safe and effective even in the treatment of facial melasma in patients with Fitzpatrick phototypes IV to V.
['Bonan|Paolo|P|', 'Verdelli|Alice|A|', 'Pieri|Laura|L|', 'Fusco|Irene|I|0000-0001-7264-8808']
D006801:Humans D053844:Lasers, Solid-State D008548:Melanosis D012867:Skin
675-nm laser facial melasma phototypes IV to V (or darker phototypes)