Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy.
PURPOSE
To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A).


METHODS
Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A.


RESULTS
Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure.


CONCLUSIONS
The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.
['Srour|Mayer|M|', 'Querques|Giuseppe|G|', 'Semoun|Oudy|O|', 'El Ameen|Ala|A|', 'Miere|Alexandra|A|', 'Sikorav|Anne|A|', 'Zambrowski|Olivia|O|', 'Souied|Eric H|EH|']
D000368:Aged D000369:Aged, 80 and over D002829:Choroid D020256:Choroidal Neovascularization D005260:Female D005451:Fluorescein Angiography D005500:Follow-Up Studies D005654:Fundus Oculi D006801:Humans D008297:Male D008875:Middle Aged D011127:Polyps D011446:Prospective Studies D012039:Regional Blood Flow D012171:Retinal Vessels D012720:Severity of Illness Index D041623:Tomography, Optical Coherence
Imaging Neovascularisation Retina