Five year outcomes of hypofractionated simultaneous integrated boost irradiation in breast conserving therapy; patterns of recurrence.
In 2005, we introduced hypofractionated 3-dimensional conformal radiotherapy with a simultaneous integrated boost (3D-CRT-SIB) technique after breast conserving surgery. In a consecutive series of 752 consecutive female invasive breast cancer patients (stages I-III) the 5-year actuarial rate for local control was 98.9%. This new technique gives excellent 5-year local control.
['Bantema-Joppe|Enja J|EJ|', 'Vredeveld|Eline J|EJ|', 'de Bock|Geertruida H|GH|', 'Busz|Dianne M|DM|', 'Woltman-van Iersel|Marleen|M|', 'Dolsma|Wil V|WV|', 'van der Laan|Hans Paul|HP|', 'Langendijk|Johannes A|JA|', 'Maduro|John H|JH|']
D000368:Aged D000369:Aged, 80 and over D001943:Breast Neoplasms D015331:Cohort Studies D003131:Combined Modality Therapy D016001:Confidence Intervals D018572:Disease-Free Survival D019583:Dose Fractionation, Radiation D005260:Female D005500:Follow-Up Studies D006801:Humans D021621:Imaging, Three-Dimensional D015412:Mastectomy, Segmental D008875:Middle Aged D009361:Neoplasm Invasiveness D009364:Neoplasm Recurrence, Local D009367:Neoplasm Staging D009426:Netherlands D011879:Radiotherapy Dosage D018714:Radiotherapy, Adjuvant D020266:Radiotherapy, Conformal D012189:Retrospective Studies D018570:Risk Assessment D016019:Survival Analysis D013997:Time Factors D016896:Treatment Outcome
Simultaneous integrated boost Breast conserving therapy Radiotherapy Local control