Effect of microscopy-assisted portoenterostomy (MAPE) for biliary atresia.
PURPOSE
Portoenterostomy (PE) is the standard treatment for biliary atresia (BA). However, micro-bile ducts are difficult to identify with surgical loupes and dissect systematically. We report the effects of our attempts to dissect hilar tissue using a surgical microscope.


METHODS
Microscopy-assisted portoenterostomy (MAPE) was initiated in 2014. Patients born between 2000 and 2013 who underwent PE until day 70 without a surgical microscope for BA were gathered as historical control. MAPE in re-do PE cases (Re-MAPE) was evaluated in the same manner.


RESULTS
Ten patients underwent MAPE for BA during the study period. 17 patients in the conventional PE group were gathered. In the MAPE group, the jaundice clearance rate was 80%, compared with 53% in the conventional PE group. Re-MAPE was performed in four patients, who had a jaundice clearance rate of 75%, essentially identical to the rate with initial MAPE. At age 4 years, the native liver survival rate was 58% in the MAPE group and 38% in the conventional PE group. The native liver survival rate in the Re-MAPE group was 75%.


CONCLUSION
MAPE is useful for sharing the surgical field during open PE in patients with BA. It may improve the rate of jaundice clearance.
['Ueno|Takehisa|T|', 'Kodama|Tasuku|T|', 'Noguchi|Yuki|Y|', 'Nomura|Motonari|M|', 'Saka|Ryuta|R|', 'Takama|Yuichi|Y|', 'Tazuke|Yuko|Y|', 'Bessho|Kazuhiko|K|', 'Okuyama|Hiroomi|H|']
D001656:Biliary Atresia D005260:Female D006801:Humans D007223:Infant D008297:Male D008853:Microscopy D011171:Portoenterostomy, Hepatic D012189:Retrospective Studies D025321:Surgery, Computer-Assisted D016896:Treatment Outcome
Micro-bile duct Jaundice clearance Native liver survival Liver transplantation