Randomized Controlled Trials for the Treatment of Hidradenitis Suppurativa.
Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease. Several treatment modalities are available, but most of them lack high-quality evidence. A systematic search was performed to identify all randomized controlled trials for the treatment of HS in order to review and evaluate the evidence. Recommendations for future randomized controlled trials include using validated scores, inclusion of patient rated outcomes, and thorough report of side effects. Evidence for long-term treatment and benefit/risk ratio of available treatment modalities is needed in order to enhance evidence-based treatment in daily clinical practice. Combining surgery with antiinflammatory treatment warrants further investigation.
['van Rappard|Dominique C|DC|', 'Mekkes|Jan R|JR|', 'Tzellos|Thrasivoulos|T|']
D000900:Anti-Bacterial Agents D003879:Dermatologic Agents D062109:Dermatologic Surgical Procedures D019304:Ethinyl Estradiol-Norgestrel Combination D017497:Hidradenitis Suppurativa D006728:Hormones D006801:Humans D000069285:Infliximab D062325:Intense Pulsed Light Therapy D053685:Laser Therapy D028022:Low-Level Light Therapy D017063:Outcome Assessment, Health Care D016032:Randomized Controlled Trials as Topic
Randomized controlled trials Treatment Hidradenitis suppurativa Surgery Antibiotics Biologics Evidence based Laser