Relationship between preterm birth and post-partum periodontal maternal status: a hospital-based Romanian study.
PURPOSE
This cross-sectional case-control study of post-partum women aimed to estimate whether maternal periodontitis was a predictive contributor to preterm birth and to identify other risk factors associated with preterm birth in our target population.


METHODS
The case group included women who delivered preterm (74 cases) and the control group included women who had a normal term delivery (120 controls). Medical records, a 16-item questionnaire, and a full-mouth periodontal examination were used to collect information about socio-demographic characteristics, general health problems, birth-related information, behavioral factors and periodontal status. Logistic regression analysis was used to estimate the strength of the relationship between predictors and the categorical outcome variable, preterm birth.


RESULTS
The bivariate analysis revealed the significant associations between preterm birth and socio-demographic factors (educational level, p = 0.003), antepartum smoking habit (p = 0.001) and birth weight lower than 2500 g (p < 0.001). The multivariate analysis highlighted that the presence of post-partum maternal periodontitis and its severity remained independent risk factors of preterm birth in the presence of antepartum smoking habit and route of delivery [adjusted OR 2.26, 95% CI (1.06; 4.82), respectively, OR 3.46, 95% CI (1.08; 11.15)].


CONCLUSION
Post-partum maternal periodontal disease and its severity might, in part, be considered as contributor to preterm deliveries before 37 weeks of gestation.
['Micu|I C|IC|0000-0001-5590-6692', 'Roman|A|A|', 'Ticala|F|F|', 'Soanca|A|A|', 'Ciurea|A|A|', 'Objelean|A|A|', 'Iancu|M|M|0000-0002-4557-5364', 'Muresan|D|D|', 'Caracostea|G V|GV|']
D000328:Adult D001724:Birth Weight D016022:Case-Control Studies D003430:Cross-Sectional Studies D005260:Female D005317:Fetal Growth Retardation D006761:Hospitals D006801:Humans D007230:Infant, Low Birth Weight D007231:Infant, Newborn D010512:Periodontal Index D010518:Periodontitis D049590:Postpartum Period D011247:Pregnancy D011251:Pregnancy Complications, Infectious D011256:Pregnancy Outcome D047928:Premature Birth D012307:Risk Factors D012383:Romania D012907:Smoking D014028:Tobacco Smoke Pollution
Preterm birth Periodontitis Periodontal disease Clinical attachment loss Probing depth