Lepidic predominant adenocarcinoma with aerogenous spread of mucin in a young patient -- a case report.
We present a unique case of a 26 year-old female non-smoker who expired following treatment for presumed pneumonias. At autopsy, lepidic predominant adenocarcinoma with aerogenous spread of mucin without evidence of invasion, a rare diagnosis that previously would have fallen under the umbrella of "bronchioloalveolar carcinoma," was found. Histopathology showed mucin-secreting neoplastic cells lining the alveolar walls, as well as exfoliated and dense aggregates of mucinous debris filling the alveoli. The immediate cause of death was respiratory failure, most likely due to the significant amount of tumor-produced mucin that filled the alveolar spaces, which literally drowned the patient.
['Nguyen|Elise|E|', 'Hakimi|Matthew|M|', 'Chavoshan|Bahman|B|', 'Stringer|William|W|', 'French|Samuel W|SW|']
D002282:Adenocarcinoma, Bronchiolo-Alveolar D000328:Adult D017809:Fatal Outcome D005260:Female D006801:Humans D008168:Lung D008175:Lung Neoplasms D009077:Mucins
Lepidic predominant adenocarcinoma Aerogenous spread Mucin Bronchioloalveolar carcinoma Lung cancer