Cutaneous candidiasis caused by Candida glabrata in a HIV/AIDS patient.
Cutaneous Candida infections may occur in patients with HIV/AIDS, cancer, receiving chemotherapy and solid organ transplantation. A 32-year-old woman was admitted to the department suffering from pruritic and erythematous plaque on left side of her face for the past two months. The patient was HIV positive, diagnosed five years previously, and had been on antiretroviral therapy (tenofovir/emtricitabine and lopinavir/ritonavir) for a year. She was not compliant with the medication. Elevated HIV RNA load and decreased CD4+ lymphocyte count were observed. Fungal elements were detected from the skin scraping sample taken from the facial plaque. Fluconazole-sensitive Candida glabrata was isolated from this sample. Topical clotrimazole ointment and systemic fluconazole 400 mg/day were used. After systemic fluconazole therapy was continued for two months, the plaque was cured. C. glabrata rarely causes cutaneous infection without involving the mucous membranes. Presentation of cutaneous fungal infections in HIV patients with decreased CD4+ T lymphocyte counts can be atypical and require extensive antifungal treatment.
['Demiraslan|Hayati|H|', 'Alabay|Selma|S|', 'Kilic|Aysegul Ulu|AU|', 'Borlu|Murat|M|', 'Doganay|Mehmet|M|']
D017088:AIDS-Related Opportunistic Infections D000328:Adult D044966:Anti-Retroviral Agents D000935:Antifungal Agents D018791:CD4 Lymphocyte Count D041221:Candida glabrata D002179:Candidiasis, Cutaneous D005260:Female D015725:Fluconazole D015658:HIV Infections D006801:Humans D016896:Treatment Outcome D019562:Viral Load
Candida glabrata HIV/AIDS cutaneous infection treatment