Clozapine in the management of persistent destructive behaviour in a 17-year-old boy with intellectual disability.
The management of challenging and refractory destructive behaviour in young patients with intellectual disability (ID) is a major issue faced by families, carers and healthcare professionals who support them. Often, paediatricians and psychiatrists use various behavioural and psychopharmacological approaches, including polypharmacy. We report on one such patient who benefitted greatly from a trial of clozapine, resulting in less aggression, improved quality of life and potentially huge cost savings. We conclude that clozapine may represent a beneficial though seldom-used option for severe, destructive behaviour in young people with ID.
['Dadlani|Navin|N|http://orcid.org/0000-0002-6202-1718', 'Small|Jacqueline|J|', 'Starling|Jean|J|', 'Einfeld|Stewart|S|']
D000293:Adolescent D014150:Antipsychotic Agents D003024:Clozapine D006801:Humans D008607:Intellectual Disability D008297:Male D011788:Quality of Life D016728:Self-Injurious Behavior
child and adolescent psychiatry developmental paediatrocs