Proanthocyanidins Should Be a Candidate in the Treatment of Cancer, Cardiovascular Diseases and Lipid Metabolic Disorder.
The conventional view of using medicines as routine treatment of an intractable disease is being challenged in the face of extensive and growing evidence that flavonoids in foods, especially proanthocyanidins (PAs), can participate in tackling fatal diseases like cancer, cardiovascular and lipid metabolic diseases, both as a precautionary measure or as a dietary treatment. Although medical treatment with medicines will remain necessary in some cases, at least in the short term, PAs' function as antioxidant, anti-inflammatory drugs, signal pathway regulators remain critical in many diseases. This review article demonstrates the physical and biological properties of PAs, summarizes the health benefits of PAs found by researchers previously, and shows the possibility and importance of being a dietary treatment substance.
['Wang|Tsz Ki|TK|', 'Xu|Shaoting|S|', 'Li|Shuang|S|', 'Zhang|Yunjian|Y|']
D000893:Anti-Inflammatory Agents D017209:Apoptosis D002318:Cardiovascular Diseases D006801:Humans D050356:Lipid Metabolism D008659:Metabolic Diseases D009369:Neoplasms D009389:Neovascularization, Pathologic D044945:Proanthocyanidins D015398:Signal Transduction
proanthocyanidins cancer cardiovascular disease lipid metabolism antioxidant signal pathway anti-inflammation