MCI of different etiologies differ on the Cognitive Assessment Battery.
OBJECTIVES
The study aims to investigate whether patients with mild cognitive impairment (MCI) who have significant vascular disease (MCI-vas) differ from those with no significant vascular disease (MCI-nov) in terms of cognitive profile when assessed with the cognitive assessment battery (CAB).


MATERIALS AND METHODS
Seventy patients clinically diagnosed with MCI were included in the study, 32 were classified as MCI-vas, and 38 as MCI-nov, together with 40 healthy controls. CAB consists of six short tests measuring speed and attention, memory, visuospatial functions, language, and executive functions.


RESULTS
The healthy controls performed better than both MCI groups on CAB. MCI-vas patients were significantly older and had fewer years of education than MCI-nov patients. When adjusted for age and education, MCI-vas performed significantly worse than MCI-nov on memory, language, and executive tests.


CONCLUSIONS
The results suggest that CAB can differentiate between MCI patients with and without vascular disease and that their cognitive profiles differ. Furthermore, CAB classified the patients as vascular and non-vascular MCI with good sensitivity and specificity.
['Nyström|O|O|', 'Wallin|A|A|', 'Nordlund|A|A|']
D000368:Aged D060825:Cognitive Dysfunction D003704:Dementia D015140:Dementia, Vascular D003937:Diagnosis, Differential D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D009483:Neuropsychological Tests D012680:Sensitivity and Specificity
mild cognitive impairment vascular disease dementia neuropsychology