Ultrawide-field fluorescein angiography for evaluation of diabetic retinopathy.
PURPOSE
To investigate the advantages of ultrawide-field fluorescein angiography (FA) over the standard fundus examination in the evaluation of diabetic retinopathy (DR).


METHODS
Ultrawide-field FAs were obtained in 118 eyes of 59 diabetic patients; 11 eyes with no DR, 71 eyes with nonproliferative diabetic retinopathy (NPDR), and 36 eyes with proliferative diabetic retinopathy (PDR), diagnosed by the standard method. The presence of peripheral abnormal lesions beyond the standard seven fields was examined.


RESULTS
Ultrawide-field FA images demonstrated peripheral microaneurysms in six (54.5%) of 11 eyes with no DR and all eyes with moderate to severe NPDR and PDR. Peripheral retinal neovascularizations were detected in three (4.2%) of 71 eyes with NPDR and in 13 (36.1%) of 36 eyes with PDR. Peripheral vascular nonperfusion and vascular leakage were found in two-thirds of eyes with severe NPDR and PDR.


CONCLUSIONS
Ultrawide-field FA demonstrates peripheral lesions beyond standard fields, which can allow early detection and a close evaluation of DR.
['Kong|Mingui|M|', 'Lee|Mee Yon|MY|', 'Ham|Don-Il|DI|']
D000368:Aged D003930:Diabetic Retinopathy D003937:Diagnosis, Differential D005260:Female D005451:Fluorescein Angiography D005654:Fundus Oculi D006801:Humans D008297:Male D008875:Middle Aged D015203:Reproducibility of Results D012160:Retina
Ultrawide-field Fluorescein angiography Diabetic retinopathy