Dedifferentiation of oncocytic epithelial-myoepithelial carcinoma to mucoepidermoid carcinoma in parotid gland: A rare case report.
Epithelial-myoepithelial carcinomas (EMCs) account for <1% of all salivary gland malignancies. Till now, 23 cases of dedifferentiated EMC have been reported to the best of our knowledge. However, dedifferentiation of oncocytic EMC to mucoepidermoid carcinoma is extremely rare. A 38-year-old female presented with right post aural swelling 4 cm × 2 cm in size for 6 months. Surgical excision was carried out, and we received partly skin-covered tissue 5 cm × 2 cm in size. Sections examined showed features of oncocytic EMC dedifferentiating into mucoepidermoid carcinoma. Myoepithelial component showed oncocytic change which was highlighted by p63.
['Rani|Poonam|P|', 'Singh|Meeta|M|', 'Mehrol|Chetna|C|', 'Gupta|Amita Jain|AJ|', 'Khurana|Nita|N|', 'Meher|Ravi|R|']
D000328:Adult D018277:Carcinoma, Mucoepidermoid D054337:Cell Dedifferentiation D005260:Female D006801:Humans D009208:Myoepithelioma D009375:Neoplasms, Glandular and Epithelial D010307:Parotid Neoplasms
oncocytic Mucoepidermoid carcinoma myoepithelial carcinoma