Disease Burden, Characteristics, and Outcomes of Methicillin-Resistant Staphylococcus aureus Bloodstream Infection in Hong Kong.
We aimed to describe disease burden, characteristics, and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) in Hong Kong. A retrospective, observational study was conducted in 26 Hong Kong public hospitals between January 2010 and December 2012. The primary outcome measures were 30-day mortality rate and infection-related hospital cost. Of 1133 patients reviewed, 727 (64.17%) were male, 1075 (94.88%) had health care-associated community-onset and 44 (3.88%) had hospital-onset MRSA infection. The mean age of patients was 76 (SD = 15) years, including 172 (15.18%) aged 20 to 59 years and 961 (84.8%) aged ≥60 years. The annual incidence rates in age groups of 20 to 59 years and ≥60 years were 0.96 to 1.148 per 100 000 and 22.7 to 24.8 per 100 000, respectively. The 30-day mortality was 367 (32.39%). Older patients (>79 years), chronic lung disease, and prior hospitalization were associated with increased mortality. The mean cost was US$10 565 (SD = 11 649; US$1 = HK$7.8). MRSA BSI was a significant burden in Hong Kong.
['You|Joyce H S|JHS|', 'Choi|Kin-Wing|KW|', 'Wong|Tin-Yau|TY|', 'Ip|Margaret|M|', 'Ming|Wai-Kit|WK|', 'Wong|Rity Yee-Kwan|RY|', 'Chan|Sze-Ngai|SN|', 'Tse|Hoi-Tung|HT|', 'Chau|Carrie T S|CTS|', 'Lee|Nelson L S|NLS|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D016470:Bacteremia D017281:Cost of Illness D003428:Cross Infection D005260:Female D006723:Hong Kong D017721:Hospital Costs D006779:Hospitals, Public D006801:Humans D008297:Male D055624:Methicillin-Resistant Staphylococcus aureus D008875:Middle Aged D012189:Retrospective Studies D013203:Staphylococcal Infections D055815:Young Adult
disease burden methicillin-resistant Staphylococcus aureus bloodstream infection Hong Kong mortality cost