Preliminary establishment of a spinal stability scoring system for multiple myeloma.
BACKGROUND
Multiple myeloma is an incurable malignant plasma cell disorder that represents the most common primary malignant bone tumor. It commonly involves bone metastasis in multiple vertebral bodies, and the Spinal Instability Neoplastic Score scoring system may not be fully applicable to multiple myeloma (MM) patients.


AIM
To evaluate the spinal stability of patients with MM spinal involvement to guide their clinical treatment.


METHODS
By using the Delphi method, we collected and extracted information through a series of questionnaires and improved it via feedback. We also preliminarily established a spinal stability scoring system for multiple myeloma.


RESULTS
Fifteen clinicians completed a second round of questionnaires and compared their answers with those of the first round of questionnaires to identify significant comments or changes that required group discussions. As a result, no further feedback was used to improve the scoring system. After integrating the information from the expert consultation questionnaire, we established the initial scoring system for MM spine stability and used the scoring system to assess a series of representative clinical cases. The MM spinal stability scoring system was created by calculating the scores of the six separate components: location, pain, number of segments, physiological curvature, comorbidities, and neurological function. The minimum value was "0", and the maximum value was "24". A score of "0-10" indicated "spine stability", a score of "11-17" indicated "potential instability", and a score of "18-24" indicated "spine instability". Patients with a score of "11-24" need an intervention such as surgery.


CONCLUSION
The initial establishment of the MM spine stability scoring system provides a vital theoretical basis for the evaluation of spine stability in individuals with MM.
['Yao|Xing-Chen|XC|', 'Shi|Xiang-Jun|XJ|', 'Xu|Zi-Yu|ZY|', 'Tan|Jie|J|', 'Wei|Yan-Zhe|YZ|', 'Qi|Lei|L|', 'Zhou|Zi-Hao|ZH|', 'Du|Xin-Ru|XR|']
Multiple myeloma Spinal instability neoplastic score Spine Patient-specific modeling Stability assessment