Comparative study on optic disc features of premature infants and full-term newborns.
BACKGROUND
To study optic disc features of premature infants and compare to that of term infants to explore the pattern and features of newborn optic disc development and provide the basis for the diagnosis of newborn optic disc disease.


METHODS
This was a prospective clinical research. Newborns underwent newborn fundus disease screening from January 1st, 2016 to October 31st, 2016 in the neonatal ward of Ruian City Maternal and Child Health Hospital were selected. RetCam 3 Version6.1.25.0 Wide-Field Digital Pediatric Retinal Imaging System developed by Clarity Medical Systems, Inc was adopted to conduct fundus examination on both eyes, 130 degree wide-angle lens was used to film the images centering optic disc.


RESULTS
For both premature infants and full-term newborns, vertical diameter of the optic disc to lateral diameter of the optic disc ratio was > 1, and the shape of the optic disc was a vertical oval. The difference of each optic disc parameter between premature infants and full-term newborns was not statistically significant (P > 0.05). There's a difference of constitution of sclerotic ring type on optic disc between premature infants and full-term newborns. Among which, the proportion of single ring type and double ring type in premature infants was higher than that in full-term newborns (P < 0.05). The proportion of no ring type in full-term newborns was higher than that in premature infants (P < 0.05). The proportion of mixed type had no significant difference (P > 0.05) between premature infants and full-term newborns.


CONCLUSIONS
We found that The proportion of mature types (single ring type and double ring type) in full-term newborns was higher than that in premature infants. While there's no statistical difference of the proportion of mixed types between premature infants and full-term newborns. Double ring type was a normal stage of the development of optic disc.
['Feng|Xiaofen|X|', 'Nan|Yan|Y|', 'Pan|Jiandong|J|', 'Zou|Ruitao|R|', 'Shen|Lijun|L|', 'Chen|Feng|F|']
D002648:Child D005654:Fundus Oculi D005865:Gestational Age D006801:Humans D007223:Infant D007231:Infant, Newborn D007234:Infant, Premature D009898:Optic Disk D011446:Prospective Studies
Premature infant Wide-Field Digital Pediatric Retinal Imaging System Optic disc parameter Full‐term newborns Shape of sclerotic ring and optic disc