Brønsted Acid-Catalyzed Synthesis of N-Arylindoles from 2-Vinylanilines and Quinones.
In the presence of a quinone, Brønsted acid-catalyzed intramolecular C-N bond formation of o-vinylanilines by electrophilic cyclization was developed, giving the corresponding N-arylindoles in good to high yields. The reaction worked well for o-vinylanilines with terminal and internal C=C double bonds.
['Zhang|Han-Ming|HM|', 'Gao|Zhong-Hua|ZH|', 'Yi|Liang|L|', 'Ye|Song|S|']
Brønsted acid C−N bond formation aniline carbocation synthetic methods