Differentiating Familial Neuropathies from Guillain-Barré Syndrome.
Differentiating Guillain-Barré syndrome (GBS) from inherited neuropathies and other acquired peripheral neuropathies requires understanding the atypical presentations of GBS and its variant forms, as well as historical and physical features suggestive of inherited neuropathies. GBS is typically characterized by the acute onset of ascending flaccid paralysis, areflexia, and dysesthesia secondary to peripheral nerve fiber demyelination. The disorder usually arises following a benign gastrointestinal or respiratory illness, is monophasic, reaches a nadir with several weeks, and responds to immunomodulatory therapy. Inherited neuropathies with onset before adulthood, whose presentation may mimic Guillain-Barré syndrome, are reviewed.
['Bordini|Brett J|BJ|', 'Monrad|Priya|P|']
D002648:Child D003937:Diagnosis, Differential D020275:Guillain-Barre Syndrome D006801:Humans D056747:Immunomodulation D007167:Immunotherapy D010523:Peripheral Nervous System Diseases
Guillain-Barré syndrome Acute inflammatory demyelinating polyradiculoneuropathy Charcot-Marie-Tooth hereditary neuropathy Congenital neuropathy