Update on appropriate use criteria for amyloid PET imaging: dementia experts, mild cognitive impairment, and education.
Amyloid PET imaging is a novel diagnostic test that can detect in living humans one of the two defining pathologic lesions of Alzheimer disease, amyloid-β deposition in the brain. The Amyloid Imaging Task Force of the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging previously published appropriate use criteria for amyloid PET as an important tool for increasing the certainty of a diagnosis of Alzheimer disease in specific patient populations. Here, the task force further clarifies and expands 3 topics discussed in the original paper: first, defining dementia experts and their use of proper documentation to demonstrate the medical necessity of an amyloid PET scan; second, identifying a specific subset of individuals with mild cognitive impairment for whom an amyloid PET scan is appropriate; and finally, developing educational programs to increase awareness of the amyloid PET appropriate use criteria and providing instructions on how this test should be used in the clinical decision-making process.
['Johnson|Keith A|KA|', 'Minoshima|Satoshi|S|', 'Bohnen|Nicolaas I|NI|', 'Donohoe|Kevin J|KJ|', 'Foster|Norman L|NL|', 'Herscovitch|Peter|P|', 'Karlawish|Jason H|JH|', 'Rowe|Christopher C|CC|', 'Hedrick|Saima|S|', 'Pappas|Virginia|V|', 'Carrillo|Maria C|MC|', 'Hartley|Dean M|DM|']
D058227:Amyloidogenic Proteins D060825:Cognitive Dysfunction D003704:Dementia D006801:Humans D057054:Molecular Imaging D009683:Nuclear Medicine D049268:Positron-Emission Tomography D017410:Practice Guidelines as Topic D014481:United States
amyloid PET dementia Alzheimer disease