Low use of statins for secondary prevention in primary care: a survey in a northern Swedish population.
BACKGROUND
Cholesterol-lowering therapy with statins is recommended in established cardiovascular disease (CVD) and should be considered for patients at high cardiovascular risk. We surveyed statin treatment before first-time myocardial infarction in clinical practice compared to current guidelines, in patients with and without known CVD in primary care clinics with general practitioners (GPs) on short-term contracts vs. permanent staff GPs.


METHODS
A total of 931 patients (345 women) in northern Sweden were enrolled in the study between November 2009 and December 2014 and stratified by prior CVD, comprising angina pectoris, revascularisation, ischaemic stroke or transitory ischaemic attack, or peripheral artery disease. Primary care clinics were classified by the proportion of GP salaries that were paid to GPs working on short-term contracts: low (0-9 %), medium (10-39 %), or high (≥40 %). We used logistic regression to identify determinants of statin treatment.


RESULTS
Among patients with prior CVD, only 34.5 % received statin treatment before myocardial infarction. The probability of statin treatment decreased with age (≥70 years OR 0.30; 95 % CI 0.13-0.66) and female gender (OR 0.39; 95 % CI 0.20-0.78) but increased in patients with diabetes (OR 3.52; 95 % CI 1.75-7.08). Among patients with prior CVD, the type of primary care clinic was not predictive of statin treatment. In the entire study cohort, 17.3 % of patients were treated with statins; women < 70 years old were more likely to receive statin treatment than women ≥70 years old (OR 3.24; 95 % CI 1.64-6.38), and men ≥70 years old were twice as likely to be treated with statins than women of the same age (OR 2.22; 95 % CI 1.31-3.76) after adjusting for diabetes and CVD. Overall, patients from clinics with predominantly permanent staff GPs received statin therapy less frequently than those with GPs on short-term contracts.


CONCLUSIONS
In patients with prior CVD we found considerable under-treatment with statins, especially among women and the elderly. Methodologies for case findings, recall, and follow-up need to be improved and implemented to reach the goals for CVD prevention in clinical practice.
['Nilsson|Gunnar|G|', 'Samuelsson|Eva|E|', 'Söderström|Lars|L|', 'Mooe|Thomas|T|']
D000367:Age Factors D000368:Aged D000369:Aged, 80 and over D000554:Ambulatory Care Facilities D002318:Cardiovascular Diseases D004651:Employment D005260:Female D058005:General Practitioners D019538:Health Care Surveys D006801:Humans D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors D008297:Male D008875:Middle Aged D009203:Myocardial Infarction D017410:Practice Guidelines as Topic D011320:Primary Health Care D055502:Secondary Prevention D012737:Sex Factors D013548:Sweden
Statins Secondary prevention Cardiovascular disease Myocardial infarction