Ascorbic acid-induced oxalate nephropathy: a case report and discussion of pathologic mechanisms.
Oxalate nephropathy is associated with hereditary hyperoxaluria, Crohn disease, and previous gastric or intestinal surgery, especially in the setting of increased oxalate intake or ethylene glycol ingestion. We present a patient whose intake of vitamin C supplements (2 g/day), exacerbated by predisposing factors of prior small bowel obstruction and resection, and benign prostate hyperplasia (BPH), resulted in acute kidney injury due to oxalate nephropathy. We review past reports of vitamin C-induced oxalate nephropathy and discuss the underlying precipitating factors.
['Lin|Weijie Violet|WV|', 'Turin|Christie Gloria|CG|', 'McCormick|David Walter|DW|', 'Haas|Christopher|C|', 'Constantine|Gregory|G|']
D058186:Acute Kidney Injury D000368:Aged D001205:Ascorbic Acid D019587:Dietary Supplements D006801:Humans D007421:Intestine, Small D008297:Male D010070:Oxalates D012307:Risk Factors
Vitamin C Acute renal failure Dialysis