Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center.
BACKGROUND
Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). Facial papules have been associated with worse prognosis.


OBJECTIVES
We sought to detect the prevalence of facial and extrafacial lesions and to analyze their relation to demographic and clinical variables in a large and ethnically diverse series of patients with FFA.


METHODS
Charts of patients diagnosed with FFA between January 1, 2015, and December 31, 2017, at the Department of Dermatology, University of Miami, were reviewed retrospectively.


RESULTS
91 patients (87 women and 4 men) met inclusion criteria: 45% (n = 41) were of Hispanic/Latino ethnicity, and 34% (n = 30) were premenopausal. Facial papules were most commonly detected (41% among Hispanic/Latino patients). Significant associations were found between: (1) Hispanic/Latino ethnicity and any FFA-associated facial lesions, facial papules alone, or lichen planus pigmentosus alone, as well as premenopausal status; (2) any FFA-associated facial lesions or facial papules alone and premenopausal status; and (3) Hispanic/Latino ethnicity and simultaneous presence of facial and extrafacial lesions.


CONCLUSIONS
There is a significant association among Hispanic/Latino ethnicity, facial papules, and premenopausal status, which may portend a susceptibility to severer disease and prompt early and aggressive treatment in this group.
['Mervis|Joshua S|JS|', 'Borda|Luis J|LJ|', 'Miteva|Mariya|M|']
D000328:Adult D001741:African Americans D000368:Aged D000369:Aged, 80 and over D000505:Alopecia D001213:Asian Americans D015897:Comorbidity D005121:Extremities D005148:Facial Dermatoses D005260:Female D005355:Fibrosis D005431:Florida D006630:Hispanic or Latino D006801:Humans D008010:Lichen Planus D008297:Male D008875:Middle Aged D009333:Neck D017697:Premenopause D012189:Retrospective Studies D012867:Skin D060726:Torso D044465:Whites
Facial papule Lichen planus pigmentosus Hair loss Lichen planopilaris Scarring alopecia