Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia.
Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.
['Squire|Michele M|MM|', 'Carter|Glen P|GP|', 'Mackin|Kate E|KE|', 'Chakravorty|Anjana|A|', 'Norén|Torbjörn|T|', 'Elliott|Briony|B|', 'Lyras|Dena|D|', 'Riley|Thomas V|TV|']
D000818:Animals D000831:Animals, Newborn D000900:Anti-Bacterial Agents D001426:Bacterial Proteins D001427:Bacterial Toxins D016360:Clostridioides difficile D004761:Enterocolitis, Pseudomembranous D008297:Male D051379:Mice D008810:Mice, Inbred C57BL D016133:Polymerase Chain Reaction D015995:Prevalence D021521:Ribotyping D016019:Survival Analysis D013552:Swine D014904:Western Australia
Clostridium difficile pigs Australia enteritis piglets PCR ribotyping C. difficile prevalence Cdiff DNA animals bacteria diarrhea domestic sequence analysis veterinary zoonoses