The Quebec Newborn Twin Study at 21.
This paper is a revised and updated edition of a previous description of the Quebec Newborn Twin Study (QNTS), an ongoing prospective longitudinal follow-up of a birth cohort of twins born between 1995 and 1998 in the greater Montreal area, Québec, Canada. The goal of QNTS is to document individual differences in the cognitive, behavioral, and social-emotional aspects of developmental health across childhood, their early genetic and environmental determinants, as well as their putative role in later social-emotional adjustment, school, health, and occupational outcomes. A total of 662 families of twins were initially assessed when the twins were aged 6 months. These twins and their family were then followed regularly. QNTS now has 16 waves of data collected or planned, including 5 in preschool. Over the last 24 years, a broad range of physiological, cognitive, behavioral, school, and health phenotypes were documented longitudinally through multi-informant and multimethod measurements. QNTS also entails extended and detailed multilevel assessments of proximal (e.g., parenting behaviors, peer relationships) and distal (e.g., family income) features of the child's environment. QNTS children and a subset of their parents have been genotyped, allowing for the computation of a variety of polygenic scores. This detailed longitudinal information makes QNTS uniquely suited for the study of the role of the early years and gene-environment transactions in development.
['Boivin|Michel|M|', 'Brendgen|Mara|M|', 'Dionne|Ginette|G|', 'Ouellet-Morin|Isabelle|I|', 'Dubois|Lise|L|', 'Pérusse|Daniel|D|', 'Robaey|Philippe|P|', 'Tremblay|Richard E|RE|', 'Vitaro|Frank|F|']
D000293:Adolescent D000328:Adult D002648:Child D002675:Child, Preschool D003072:Cognition Disorders D002658:Developmental Disabilities D004200:Diseases in Twins D005260:Female D005500:Follow-Up Studies D059647:Gene-Environment Interaction D006801:Humans D015994:Incidence D007223:Infant D007231:Infant, Newborn D008137:Longitudinal Studies D008297:Male D008875:Middle Aged D010358:Patient Participation D018579:Patient Selection D011446:Prospective Studies D011792:Quebec D012042:Registries D012107:Research Design D014429:Twins, Dizygotic D014430:Twins, Monozygotic D055815:Young Adult
preschool peer relationships gene–environment transactions infancy language longitudinal twin study numeracy school readiness and achievement social-emotional development