Surveying the chemical composition and antibacterial activity of essential oils from selected medicinal plants against human pathogens.
Background and Objectives
Essential oils (EOs) with different biological activities, such as antibacterial properties, are a valuable resource for developing new drugs.


Materials and Methods
Ingredients of six medicinally important EOs, including Artemisia dracunculus, Anethum graveolens, Citrus limon, Citrus sinensis, Cinnamomum zeylanicum and Zingiber officinale, were identified using GC-MS analysis. Moreover, their five major compounds were also listed. Furthermore, the half-maximal inhibitory concentration (IC50) against four important human bacteria was also investigated using the 96-well plate microdilution.


Results
C. sinensis EO with IC50 of 1.0 and 4.7 mg.mL-1 have the most effect on the growth of S. aureus and P. aeruginosa. Moreover, EOs of Cinnamomum zeylanicum (IC50: 1.0 mg. Ml-1) and Artemisia dracunculus (IC50: 1.3 mg.mL-1) significantly showed better inhibitory effect on E. coli and K. pneumoniae.


Conclusion
These EOs could be used for developing inexpensive, potent, and green antibacterial agents.
['Osanloo|Mahmoud|M|', 'Ghaznavi|Ghazal|G|', 'Abdollahi|Abbas|A|']
Antibacterial activity Essential oil Pathogens Microdilution