2BOB - extracting an H2BC and an HSQC-type spectrum from the same data set, and H2OBC - a fast experiment delineating the protonated 13 C backbone.
Two new related methods, 2BOB and H2OBC, for tracking out the backbone of protonated 13 C nuclei are presented. 2BOB extracts an H2BC and an HSQC-type spectrum from one and the same data set, and the combined information of these two spectra tracks out the molecular backbone. The faster method, H2OBC, typically requiring only a few minutes of instrument time, yields a single spectrum with distinct and different phases imposed on the H2BC and one-bond peaks thus obviating the need to separate them in the absence of complicating spectral overlap. Copyright © 2017 John Wiley & Sons, Ltd.
['Kupče|Ēriks|Ē|http://orcid.org/0000-0002-2366-0269', 'Sørensen|Ole W|OW|']
2BOB H2BC H2OBC COSY HMQC HSQC quinine structure elucidation tobramycin