COVID-19 Experience in Hemodialysis Patients: A Cue for Therapeutic Heparin-Based Strategies?
In our opinion, the use of heparin could play a crucial role in these patients. In fact, recent studies have shown that heparin, the most commonly used anticoagulant during HD procedures, had anti-inflammatory properties and a direct antiviral action, due to its ability to prevent SARS-CoV-2 pseudovirus entry into host cells. These activities, together with its anticoagulant action, could explain the ability of heparin to ameliorate COVID-19 clinical course.
['Pisani|Antonio|A|', 'Rizzo|Manuela|M|', 'Angelucci|Valentina|V|', 'Riccio|Eleonora|E|']
D000925:Anticoagulants D000086382:COVID-19 D018352:Coronavirus Infections D006493:Heparin D006801:Humans D058873:Pandemics D011024:Pneumonia, Viral D006435:Renal Dialysis
Hemodialysis Heparin Coronavirus disease 2019