Factors related to asymptomatic or severe COVID-19 infection.
The factors that may contribute to a COVID-19 patient remaining in the asymptomatic stage, or to the infection evolving into the more serious stages are examined. In particular, we refer to the TMPRSS2 expression profile, balance of androgen and estrogen, blood group-A and/or B, nonsynonymous mutations in ORF3, and proteins NS7b and NS8 in SARS-CoV-2. Also, we review other factors related to the susceptibility and pathogenicity of SARS-CoV-2.
['Mayoral|Eduardo Pérez-Campos|EP|', 'Hernández-Huerta|María Teresa|MT|', 'Pérez-Campos Mayoral|Laura|L|', 'Matias-Cervantes|Carlos Alberto|CA|', 'Mayoral-Andrade|Gabriel|G|', 'Barrios|Luis Ángel Laguna|LÁL|', 'Pérez-Campos|Eduardo|E|']
D000483:Alleles D000728:Androgens D000085962:Angiotensin-Converting Enzyme 2 D058345:Asymptomatic Infections D000086382:COVID-19 D000086422:Coronavirus RNA-Dependent RNA Polymerase D059472:Exome D005260:Female D020869:Gene Expression Profiling D020022:Genetic Predisposition to Disease D015395:Histocompatibility Antigens Class I D006801:Humans D008297:Male D008962:Models, Theoretical D009154:Mutation D016366:Open Reading Frames D020641:Polymorphism, Single Nucleotide D000086402:SARS-CoV-2 D012697:Serine Endopeptidases D017361:Viral Nonstructural Proteins D014807:Vitamin D
Factors Asymptomatic COVID-19 infection Androgen Mutation 25-Hydroxyvitamin D (25(OH)D) ACE2 Blood group Histocompatibility complex (MHC) class I