The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles.
OBJECTIVE
To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle.


DESIGN
Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA.


RESULTS
Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle.


CONCLUSION
D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.
['Tamir|Rina|R|', 'Allouche|Sarit|S|', 'Weissman|Ariel|A|', 'Haikin Herzberger|Einat|E|', 'Oberman-Farhi|Suzi|S|', 'Shalom-Paz|Einat|E|', 'Shulman|Adrian|A|', 'Wiser|Amir|A|']
D000022:Abortion, Spontaneous D000328:Adult D004107:Dilatation and Curettage D005260:Female D005307:Fertilization in Vitro D006801:Humans D016595:Misoprostol D010120:Oxytocics D011247:Pregnancy D012189:Retrospective Studies
miscarriage D&C misoprostol IVF lag period