Computer-Aided Tinnitus Detection based on Brain Network Analysis of EEG Functional Connectivity.
Background
Tinnitus known as a central nervous system disorder is correlated with specific oscillatory activities within auditory and non-auditory brain areas. Several studies in the past few years have revealed that in the most tinnitus cases, the response pattern of neurons in auditory system is changed due to auditory deafferentation, which leads to variation and disruption of the brain networks.


Objective
In this paper, we introduce an approach to automatically distinguish tinnitus individuals from healthy controls based on whole-brain functional connectivity and network analysis.


Material and Methods
The functional connectivity analysis was applied to the resting state electroencephalographic (EEG) data of both groups using Weighted Phase Lag Index (WPLI) for various frequency bands in 2-44 Hz frequency range. In this case- control study, the classification was performed on graph theoretical measures using support vector machine (SVM) as a robust classification method.


Results
Experimental results showed promising classification performance with a high accuracy, sensitivity, and speciﬁcity in all frequency bands, specifically in the beta2 frequency band.


Conclusion
The current study provides substantial evidence that tinnitus network can be successfully detected by consistent measures of the brain networks based on EEG functional connectivity.
['Mohagheghian|F|F|', 'Makkiabadi|B|B|', 'Jalilvand|H|H|', 'Khajehpoor|H|H|', 'Samadzadehaghdam|N|N|', 'Eqlimi|E|E|', 'Deevband|M R|MR|']
Tinnitus Functional Connectivity Classification Electroencephalography Network Aanalysis