Influence of involuntary cigarette smoke inhalation on osseointegration: a systematic review and meta-analysis of preclinical studies.
There are no studies that have systematically reviewed the influence of involuntary cigarette smoke inhalation (ICSI) on the stability of implants. The aim of the present study was to perform a systematic review and meta-analysis of preclinical studies that assessed the influence of involuntary cigarette smoke inhalation ICSI on osseointegration. Indexed databases (PubMed, Google-Scholar, Scopus, EMBASE, and Web of Knowledge) were searched till September 2017. Titles and abstracts of studies identified using the above-described protocol were independently screened by 2 authors. Full-texts of studies judged by title and abstract to be relevant were independently evaluated for the stated eligibility criteria. Nine studies were included. Six studies showed that ICSI compromised bone area contact around implants. In 4 studies, peri-implant bone mineral density was significantly higher in the control group than among subjects exposed to ICSI. For the effects of ICSI on the osseointegration of dental implants, significant differences could be observed for bone-to-implant contact for test subjects in cancellous (Z=-4.08, p<0.001) and cortical bone (Z=-4.31, p<0.001) respectively. ICSI may negatively influence osseointegration of dental implants. It is imperative to educate patients about the negative effects of passive smoking on dental and systemic health.
['Javed|F|F|', 'Kellesarian|S V|SV|', 'Abduljabbar|T|T|', 'Abduljabbar|A T|AT|', 'Akram|Z|Z|', 'Vohra|F|F|', 'Rahman|I|I|', 'Romanos|G E|GE|']
D000818:Animals D015519:Bone Density D015921:Dental Implants D020007:Implants, Experimental D016348:Osseointegration D051381:Rats D014028:Tobacco Smoke Pollution
osseointegration dental implants alveolar bone loss tobacco smoke pollution