A prospective study of contrast preservation using ultra-low contrast delivery technique versus standard automated contrast injector system in coronary procedures.
BACKGROUND
We aimed to assess the decrease in contrast media volume (CMV) with ultra-low contrast delivery technique (ULCD) developed at our institution versus the usual automated contrast injector system (ACIS) contrast delivery in coronary procedures.


METHODS
We analyzed the amount of contrast given in the consecutive 204 patients of the operators who use ULCD technique versus consecutive 200 patients of the other operators who use ACIS without ULCD technique for coronary angiograms and/or percutaneous coronary interventions (PCIs) from May 2017 to July 2018 at our center. We calculated the mean CMV between these groups.


RESULTS
We observed a significant reduction in mean CMV with ULCD technique versus standard ACIS, respectively: angiogram 24.8 ± 15.8 mL (n = 194) vs 42.3 ± 25.1 mL (n = 200) (p < 0.0001); PCI 23.5 ± 19.7 mL (n = 52) vs 48.2 ± 30.8 mL (n = 16) (p < 0.0070); angiogram with ad hoc PCI 53.4 ± 32.1 mL (n = 23) vs 89.7 ± 35.6 mL (n = 16) (p < 0.0024); and overall angiogram and PCI 27.4 ± 20.5 mL (n = 204) vs 44.9 ± 28.0 mL (n = 181) (p < 0.0001).


CONCLUSION
Our study showed a highly significant reduction in CMV using ULCD technique compared to standard ACIS contrast delivery in coronary invasive procedures. Even in the standard ACIS arm, CMV was significantly lower than values reported in literature, possibly due to operators' bias toward contrast preservation.
['Stys|Adam|A|', 'Gedela|Maheedhar|M|', 'Bhatnagar|Udit|U|', 'Petrasko|Marian|M|', 'Dawoud|Hazem|H|', 'Malinski|Tadeusz|T|', 'Stys|Tomasz|T|']
D000368:Aged D000465:Algorithms D003287:Contrast Media D017023:Coronary Angiography D005260:Female D006801:Humans D007267:Injections D008297:Male D062645:Percutaneous Coronary Intervention D011446:Prospective Studies D013023:South Dakota D014283:Triiodobenzoic Acids
Ultra-low contrast delivery Automated contrast injector system Contrast media Contrast-induced nephropathy