The temporal relation between seizure onset and arousal-awakening in temporal lobe seizures.
PURPOSE
Our main aim was to determine the time interval between the seizure onsets and arousal-awakening related to these seizures in patients with temporal lobe epilepsy (TLE) and to discuss the role of lateralization on arousal-awakening mechanisms.


METHODS
Thirty-three TLE patients who underwent video-EEG monitoring with simultaneous polysomnography (PSG) and had recorded nocturnal seizures were retrospectively examined. These TLE patients had 64 seizures during sleep. The onsets of seizures and arousal-awakening related to these seizures were marked according to clinical and electrophysiological features. The time interval between the seizure onset and arousal-awakening related to the seizure was compared in patients with right- or left-sided temporal lobe seizures.


RESULTS
In our TLE patients nocturnal seizures mostly followed arousal-awakening (64%). The time interval between the seizure onset and arousal-awakening related to the seizure was significantly shorter in patients with left-sided temporal lobe seizures (p=0.01).


CONCLUSION
Video-EEG monitoring and PSG with scalp electrodes in our TLE patients showed that nocturnal seizures mostly followed arousal-awakening, and it was more pronounced in those with left-sided seizures. Arousal-awakening might be a signal for subsequent seizures in patients with TLE.
['Gumusyayla|Sadiye|S|', 'Erdal|Abidin|A|', 'Tezer|F Irsel|FI|', 'Saygi|Serap|S|']
D000293:Adolescent D000328:Adult D001143:Arousal D004569:Electroencephalography D004833:Epilepsy, Temporal Lobe D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D017286:Polysomnography D012640:Seizures D013997:Time Factors D014741:Video Recording D014851:Wakefulness D055815:Young Adult
Seizure Temporal lobe epilepsy Polysomnography Sleep Awakening Hippocampal sclerosis