Expanding Therapeutic Options for Older Adults: Case-Based Updates in Breast and Lung Cancer.
Oncology care has become increasingly complex, with a dramatic increase in the number of available therapy options. Many newly developed medications have novel mechanisms of action and include targeted therapies and immunotherapy options. These agents typically have unique side effects that differ from more traditional cytotoxic chemotherapy regimens. Older adults represent the majority of patients with cancer and it is important for geriatricians and primary care providers for older adults to have a general understanding of newer agents and novel therapies, in order to aid in decision-making and supportive care strategies during oncology treatment. This review provides a case-based approach to discussing emerging therapeutic treatment options, including targeted therapies and immune-based therapies, in two common malignancies affecting older adults. Incorporation of available evidence of specific novel therapies in older adult populations is discussed. J Am Geriatr Soc 67:1012-1019, 2019.
['Magnuson|Allison|A|', 'Elias|Rawad|R|', 'Koll|Thuy|T|']
D000368:Aged D001943:Breast Neoplasms D003131:Combined Modality Therapy D003657:Decision Making D005260:Female D015577:Geriatric Assessment D006801:Humans D008175:Lung Neoplasms D008297:Male D010353:Patient Education as Topic
cancer therapy case-based review geriatric oncology