Spontaneous pregnancy rate following surgery for deep infiltrating endometriosis in infertile women: The impact of the learning curve.
OBJECTIVES
To determine whether the surgical learning curve impact the spontaneous pregnancy rate in infertile patients undergoing removal of deep infiltrating endometriosis MATERIAL AND METHODS: Single center retrospective study including the first 50 consecutive infertile women suffering from deep infiltrating endometriosis and referred to a single surgeon. All patients underwent laparoscopic removal of deep endometriosis lesions. The study population was stratified in two subgroups, namely the early group (including the first 25 cases) and the late group (comprising the 25 subsequent cases). Pregnancy and live birth rates, surgical morbidity and clinical recurrence rate were compared between study groups.


RESULTS
Overall, spontaneous pregnancy rate (40 % in the early group versus 56 % in the late group, p = 0.25), live birth rate (40 % versus 44 %, p = 0.77) and clinical recurrence rate (16 % versus 4%, p = 0.16) did not significantly differ between the study groups. Logistic regression analysis revealed that ASRM stage, EFI score, and body mass index were the only significant prognostic factors of postoperative spontaneous fertility.


CONCLUSION
Surgical resection of deep infiltrating endometriosis in infertile women is associated with high spontaneous pregnancy and live birth rates. The surgeon's learning curve does not impact postoperative fertility outcomes.
['Vidal|Fabien|F|', 'Guerby|Paul|P|', 'Simon|Cynthia|C|', 'Lesourd|Florence|F|', 'Cartron|Géraldine|G|', 'Parinaud|Jean|J|', 'Tanguy le Gac|Yann|Y|', 'Dupuis|Ninon|N|']
D000293:Adolescent D000328:Adult D015992:Body Mass Index D004715:Endometriosis D005260:Female D006801:Humans D007247:Infertility, Female D010535:Laparoscopy D059032:Learning Curve D050498:Live Birth D011247:Pregnancy D018873:Pregnancy Rate D011379:Prognosis D012189:Retrospective Studies D066231:Surgeons D055815:Young Adult
Spontaneous pregnancy Surgery Deep infiltrating endometriosis Learning curve Fertility