Norepinephrine-associated left ventricular outflow tract obstruction and systolic anterior movement.
In the perioperative setting, norepinephrine is used to increase blood pressure, an effect mediated mostly via arterial and venous vasoconstriction. Thus, norepinephrine is, allegedly, less likely to cause or worsen left ventricular outflow tract obstruction (LVOTO) than other inotropes. We report a case of norepinephrine-associated dynamic LVOTO and systolic anterior movement in a predisposed patient. This report highlights that unrecognised dynamic LVOTO may worsen shock parameters in patients treated with norepinephrine who have underlying myocardial hypertrophy.
['Mampuya|Warner Mbuila|WM|', 'Dumont|Jonathan|J|', 'Lamontagne|Francois|F|']
D000369:Aged, 80 and over D002312:Cardiomyopathy, Hypertrophic D018618:Echocardiography, Doppler, Color D017809:Fatal Outcome D006801:Humans D008297:Male D008943:Mitral Valve D009638:Norepinephrine D014662:Vasoconstrictor Agents D014694:Ventricular Outflow Obstruction
adult intensive care cardiovascular system contraindications and precautions drug therapy related to surgery unwanted effects / adverse reactions