Diagnosis of Chagasic Encephalitis by Sequencing of 28S rRNA Gene.
We report a case of chagasic encephalitis diagnosed by 28S rRNA sequencing. The diagnosis of chagasic encephalitis is challenging, given the broad differential diagnosis for central nervous system lesions in immunocompromised patients and low sensitivity of traditional diagnostics. Sequencing should be part of the diagnostic armamentarium for potential chagasic encephalitis.
['Multani|Ashrit|A|', 'Meer|Aabed|A|', 'Smith|Darvin S|DS|', 'Kheraj|Malika N|MN|', 'Plowey|Edward D|ED|', 'Blackburn|Brian G|BG|']
D000328:Adult D014355:Chagas Disease D006801:Humans D061705:Image-Guided Biopsy D016867:Immunocompromised Host D000069544:Infectious Encephalitis D008279:Magnetic Resonance Imaging D008297:Male D012339:RNA, Ribosomal, 28S D017422:Sequence Analysis, DNA D063189:Symptom Assessment D014057:Tomography, X-Ray Computed D016896:Treatment Outcome D014344:Trypanocidal Agents D014349:Trypanosoma cruzi
chagasic encephalitis 28S rRNA gene rRNA sequencing immunocompromised Chagas disease HIV/AIDS and other retroviruses Trypanosoma cruzi meningitis/encephalitis parasites protozoa