Withdrawal of hormone therapy and increased risk of cardiovascular disease.
Many menopause specialists follow the principle of prescribing postmenopausal hormone therapy (HT) for the shortest duration needed, in order to decrease the risk of some related serious adverse effects, such as breast cancer. Based on several large studies, it seems, however, that withdrawal of HT may be associated with immediate, though small increased risk of coronary heart disease and stroke. Cessation of HT correlates with increased risk of fractures as well. This information should be relayed to hormone users while discussing the continuation of HT with their health-care provider, but, since the potential cardiovascular harm is actually very small, it should not deter symptomatic women from using HT when needed.
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D002318:Cardiovascular Diseases D015914:Estrogen Replacement Therapy D004967:Estrogens D005260:Female D006801:Humans D008875:Middle Aged D017698:Postmenopause D012307:Risk Factors D013997:Time Factors D016387:Women's Health
Hormone therapy cardiovascular disease risk