Accuracy of actual resected liver volume in anatomical liver resections guided by 3-dimensional parenchymal staining using fusion indocyanine green fluorescence imaging.
BACKGROUND
The aim of this study was to assess the accuracy of actual resected liver volume (ARLV) in anatomical liver resections (ALRs) guided by 3-dimensional parenchymal staining using fusion indocyanine green fluorescence imaging (IGFI).


METHODS
Patients eligible for hepatic resection were enrolled in the current study from January 2016 to November 2017. All patients underwent surgery planning based on Medical Image Three-Dimensional Visualization System (MI-3DVS) before the operation, in which predicted resected liver volumes (PRLVs) were calculated. Under 3-dimensional guidance by fusion IGFI, ALRs were performed and ARLVs were measured. Simple linear regression, intra-class correlation coefficient (ICC) and Bland-Altman analysis were used to evaluate the relationship and agreement between PRLV and ARLV.


RESULTS
Of the 27 patients who achieved valid demarcation by fusion IGFI, 12 (44.4%) received hemihepatectomy, while 10 (37.0%) and five (18.5%) underwent sectionectomy and segmentectomy, respectively. The relationship and agreement between PRLV (481.37 ± 189.47 cm³) and ARLV (450.57 ± 205.19 cm³) were then evaluated. The simple regression equation obtained was PRLV = 0.874 × ARLV + 87.75 (R = 0.946; P = 0.000). Meanwhile, ARLV (ICC = 0.943) achieved an excellent agreement with PRLV ( P < 0.001); 25 of 27 dots were in the range of 95% confidence interval in Bland-Altman analysis.


CONCLUSIONS
In the study, these findings validated the consistency between PRLV calculated by MI-3DVS and ARLV guided by fusion IGFI, which proved that IGFI can accurately guide anatomical hepatectomy. Generally, fusion IGFI can provide a valid, feasible and accurate demarcation line, which can confer precision to hepatic resection.
['Yang|Jian|J|', 'Tao|Hai-Su|HS|', 'Cai|Wei|W|', 'Zhu|Wen|W|', 'Zhao|Dong|D|', 'Hu|Hao-Yu|HY|', 'Liu|Jun|J|', 'Fang|Chi-Hua|CH|http://orcid.org/0000-0002-1112-1540']
D006528:Carcinoma, Hepatocellular D018281:Cholangiocarcinoma D005260:Female D005456:Fluorescent Dyes D006498:Hepatectomy D006801:Humans D021621:Imaging, Three-Dimensional D007208:Indocyanine Green D008099:Liver D008113:Liver Neoplasms D008297:Male D008875:Middle Aged D061848:Optical Imaging D011300:Preoperative Care D011446:Prospective Studies D013194:Staining and Labeling D014057:Tomography, X-Ray Computed
anatomical liver resections (ALRs) indocyanine green fluorescence imaging (IGFI) 3D