Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer.
Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008-December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3-1.9) and 98.3% (95% CI 97.3-99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity.
['Rodriguez-Ibarria|Nieves G|NG|', 'Pinar|Ma Beatriz|MB|', 'García|Laura|L|', 'Cabezón|M Auxiliadora|MA|', 'Lloret|Marta|M|', 'Rey-Baltar|Ma Dolores|MD|', 'Rdguez-Melcón|J Ignacio|JI|', 'Lara|Pedro C|PC|']
D000368:Aged D001918:Brachytherapy D001943:Breast Neoplasms D018270:Carcinoma, Ductal, Breast D055088:Early Detection of Cancer D005260:Female D006801:Humans D008875:Middle Aged D009364:Neoplasm Recurrence, Local D011879:Radiotherapy Dosage
Partial breast irradiation Brachytherapy Early breast cancer Breast cancer