Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection.
BACKGROUND
Bordetella bronchiseptica (B.bronchiseptica) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. We present a rare case of B. bronchiseptica pneumonia in a patient with lung cancer.


CASE PRESENTATION
A 52-year-old white male with non small cell lung cancer developed fever during treatment with nivolumab. A persistent productive cough and a deterioration in his clinical condition led to his hospitalization for evaluation. Bronchoscopy was performed and a diagnosis of B. bronchiseptica pneumonia was made. The infection was successfully managed by antiobiotic therapy.


CONCLUSIONS
B. bronchiseptica is a pathogen that can cause serious infection in humans, especially in immunocompromised or immunoincompetent individuals. In our patient it showed unusual resistance to cephalosporins and poor sensitivity to amikacin. To our knowledge this is the first case of such an infection in a lung cancer patient undergoing treatment with nivolumab. When B. bronchiseptica is identified, the possibility of a nosocomial transmission must be considered.
['Monti|Manlio|M|', 'Diano|Danila|D|', 'Allegrini|Francesco|F|', 'Delmonte|Angelo|A|', 'Fausti|Valentina|V|', 'Cravero|Paola|P|', 'Marcantognini|Giulia|G|', 'Frassineti|Giovanni Luca|GL|']
D000583:Amikacin D000900:Anti-Bacterial Agents D001885:Bordetella Infections D016950:Bordetella bronchiseptica D001999:Bronchoscopy D002289:Carcinoma, Non-Small-Cell Lung D003371:Cough D006801:Humans D008175:Lung Neoplasms D008297:Male D008875:Middle Aged D018410:Pneumonia, Bacterial
Bordetella bronchiseptica Rare infection Nivolumab Cavitary lung lesion Nosocomial infection