Polypoidal Choroidal Vasculopathy Amongst Nigerians; A Multicenter Study.
Objective
To investigate the prevalence and presentation of polypoidal choroidal vasculopathy (PCV) in Nigerians.


Methods
A cross-sectional, multicenter, hospital-based, descriptive study. Data were collected prospectively between January and December 2018, from consecutive patients diagnosed to have a retina disease at the general outpatient and retinal clinics of four eye departments in Nigeria. All participants had visual acuity, refraction, intraocular pressure, anterior segment examination, and dilated fundus examination. Some patients had fundus fluorescein angiography, optical coherence tomography (OCT), and OCT angiography (OCTA). Systemic comorbidity was determined by medical history and systemic evaluation. Diagnosis of PCV was based on clinical findings, and in some patients using OCT.


Results
A total of 8,614 patients were seen and 15 patients (18 eyes) were diagnosed to have PCV giving a yearly hospital-based prevalence of 0.17%. The mean age at presentation was 63.27 ± 11.5 years (range 44-84 years). There were nine females (60%). The male: female ratio was 1.5:1. Twelve (66.7%) of the 18 eyes were blind, 16.7% had severe visual impairment while 11.1% had mild visual impairment. Seven eyes (38.9%) had vitreous hemorrhage. Of the 12 blind eyes, 50% had vitreous hemorrhage (P = 0.463). Nine patients (60%) had systemic hypertensive as comorbidity (P = 0.016).


Conclusion
PCV is a cause of vision loss among Nigerians. Majority of the eyes were blind and 50% of blind eyes had vitreous hemorrhage. Since Indocyanine Green Angiography is the most appropriate imaging technology and is mostly unavailable in Nigeria, efforts should be made to address this need and improve the diagnostic accuracy.
['Adenuga|O|O|', 'Okonkwo|O N|ON|', 'Udoh|M M|MM|', 'Ovienra|W|W|', 'Ibanga|A|A|', 'Agweye|C|C|', 'Nkanga|D|D|', 'Akanbi|T|T|', 'Oyekunle|I|I|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D002829:Choroid D003430:Cross-Sectional Studies D005260:Female D005451:Fluorescein Angiography D006801:Humans D008297:Male D008875:Middle Aged D009549:Nigeria D012189:Retrospective Studies D041623:Tomography, Optical Coherence
polypoidal choroidal vasculopathy retina diseases Nigeria vitreous hemorrhage Indocyanine Green Angiography