RNA editing of cytochrome c maturation transcripts is responsive to the energy status of leaf cells in Arabidopsis thaliana.
Overexpression of AtPAP2, a phosphatase located on the outer membranes of chloroplasts and mitochondria, leads to higher energy outputs from these organelles. AtPAP2 interacts with seven MORF proteins of the editosome complex. RNA-sequencing analysis showed that the editing degrees of most sites did not differ significantly between OE and WT, except some sites on the transcripts of several cytochrome c maturation (Ccm) genes. Western blotting of 2D BN-PAGE showed that the patterns of CcmFN1 polypeptides were different between the lines. We proposed that AtPAP2 may influence cytochrome c biogenesis by modulating RNA editing through its interaction with MORF proteins.
['Sun|Yuzhe|Y|', 'Law|Yee-Song|YS|', 'Cheng|Shifeng|S|', 'Lim|Boon Leong|BL|']
D017360:Arabidopsis D045304:Cytochromes c D004734:Energy Metabolism D017393:RNA Editing D014157:Transcription Factors
RNA editing Cytochrome c AtPAP2 MORF Ccm