Application of microextraction techniques in alternative biological matrices with focus on forensic toxicology: a review.
The interest in alternative biological matrices (e.g., hair and saliva) for forensic toxicology analysis has increased, and recent developments in sample preparation have targeted rapid, cheap, efficient and eco-friendly methods, including microextraction techniques. For this review, we have gathered information about these two hot topics. We discuss the composition, incorporation of analytes and advantages and disadvantages of different biological matrices, and also present the operation principles of the most reported microextraction procedures and their application in forensic toxicology. The outcome of this review may encourage future forensic researches into alternative samples and microextraction techniques.
['Costa|Bruno Ruiz Brandão da|BRBD|https://orcid.org/0000-0002-3927-3853', 'Santos Júnior|Wilson José Ramos|WJR|https://orcid.org/0000-0002-6733-6161', 'Maximiano|Isabela Fernanda|IF|', 'Gomes|Nayna Cândida|NC|', 'Freitas|Bruno Toledo|BT|', 'De Martinis|Bruno Spinosa|BS|']
D053593:Forensic Toxicology D006801:Humans D052617:Solid Phase Microextraction
microextraction sample preparation alternative samples drugs of abuse green chemistry