Antidepressant-induced sexual dysfunction in men.
Most of the available antidepressant medications, including tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, and dual noradrenergic/serotonergic reuptake inhibitors have been reported to be associated with sexual dysfunction in both sexes. This manuscript reviews evidence concerning the relative incidence of treatment emergent sexual dysfunction in men being treated with antidepressant drugs. Both double-blind controlled trials and large clinical series report a high incidence of sexual dysfunction, especially ejaculatory delay, with serotonergic drugs. The incidence of sexual dysfunction in men appears to be much lower with drugs whose primary mechanism of action involves adrenergic or dopaminergic systems.
['Segraves|Robert Taylor|RT|', 'Balon|Richard|R|']
D000928:Antidepressive Agents D000929:Antidepressive Agents, Tricyclic D018849:Controlled Clinical Trials as Topic D003866:Depressive Disorder D004542:Ejaculation D006801:Humans D008297:Male D008996:Monoamine Oxidase Inhibitors D017367:Serotonin Uptake Inhibitors D012735:Sexual Dysfunction, Physiological
Sexual dysfunction Antidepressant Serotonin Sexual disorder Side effect