Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case-control study.
OBJECTIVE
To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia.


METHODS
In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included.


RESULTS
Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women.


CONCLUSION
Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.
['Celik|Samettin|S|https://orcid.org/0000-0002-9889-5249', 'Soyer Çalışkan|Canan|C|https://orcid.org/0000-0002-6407-1129']
D000328:Adult D016022:Case-Control Studies D021984:Cyclophilin A D005260:Female D006801:Humans D011225:Pre-Eclampsia D011247:Pregnancy D011262:Pregnancy Trimester, Second D011446:Prospective Studies D055815:Young Adult
cyclophilin A preeclampsia Pregnancy gestational hypertension predictive models