Borylation of unactivated aryl chlorides under mild conditions by using diisopropylaminoborane as a borylating reagent.
The synthesis of arylboronic ester derivatives from aryl chlorides by using aryl(amino)boranes is described. Palladium-catalyzed coupling between aryl chlorides and diisopropylaminoborane leads to the formation of a CB bond under mild conditions. A wide range of functional groups are tolerated, making this method particularly useful for the borylation of functionalized aromatics.
['Guerrand|Hélène D S|HD|', 'Marciasini|Ludovic D|LD|', 'Jousseaume|Mélissa|M|', 'Vaultier|Michel|M|', 'Pucheault|Mathieu|M|']
aromatics boron halogens homogeneous catalysis palladium