Cardiometabolic Risk, Socio-Psychological Factors, and Trajectory of Grip Strength Among Older Japanese Adults.
OBJECTIVE
To examine the association between cardiometabolic risk (percent body fat [BF%], triglycerides [TG], high-density lipoprotein [HDL]-cholesterol, hemoglobin A1c [HbA1c]), socio-psychological factors (education and self-rated health [SRH]), and trajectories of grip strength (GS) in older adults.


METHOD
Longitudinal 8-year data from 1,381 Japanese adults aged 65 years or above were analyzed using hierarchical linear models, stratified according to gender.


RESULTS
GS declined following a linear trajectory. In both genders, higher BF% was associated with weaker GS, but not with the rate of decline. GS trajectory did not correlate with baseline TG, HDL-C, or HbA1c. Cardiometabolic factors mediated educational differences in GS intercept in both genders. In women, better SRH predicted stronger GS. The effect of SRH was robust to adjustments for cardiometabolic risk.


DISCUSSION
In older adults, GS and its rate of decline are selectively associated with both cardiometabolic risk and socio-psychological characteristics. Cardiometabolic risk mediates educational disparities in GS but not differences in subjective assessments of health.
['Botoseneanu|Anda|A|', 'Bennett|Joan M|JM|', 'Nyquist|Linda|L|', 'Shinkai|Shoji|S|', 'Fujiwara|Yoshinori|Y|', 'Yoshida|Hiroto|H|', 'Aiello|Allison|A|', 'Cigolle|Christine T|CT|', 'Liang|Jersey|J|']
D000273:Adipose Tissue D000368:Aged D001823:Body Composition D002318:Cardiovascular Diseases D008076:Cholesterol, HDL D059026:Diagnostic Self Evaluation D004522:Educational Status D005260:Female D006442:Glycated Hemoglobin A D018737:Hand Strength D006801:Humans D007564:Japan D008137:Longitudinal Studies D008297:Male D012307:Risk Factors D017678:Sex Distribution D014280:Triglycerides
grip strength aging Japan cardiometabolic risk factors