Hitting the mark: blood pressure targets and agents in those with prevalent cardiovascular disease and heart failure.
Blood pressure (BP) is one of the key modifiable risk factors for cardiovascular disease (CVD) both in primary and secondary prevention of disease. In this review, we discuss BP treatment in prevalent CVD and heart failure. Evidence for specific agents based on their neurohormonal effects and evidence for target values for systolic or diastolic BP are covered. The potential adverse effects of overtreatment of BP are also discussed. BP targets for those with CVD should generally be less than 140/90 mm Hg but require individualization of therapy for any further reduction based on the clinical setting.
['Rifkin|Dena E|DE|', 'Kiernan|Michael|M|', 'Sarnak|Mark J|MJ|']
D000959:Antihypertensive Agents D001682:Biological Availability D001794:Blood Pressure D001795:Blood Pressure Determination D003324:Coronary Artery Disease D006333:Heart Failure D006801:Humans D006973:Hypertension D012307:Risk Factors
Blood pressure Heart failure Atherosclerosis Blood pressure medications