Practical guide to quantification of hepatic iron with MRI.
Our intention is to demystify the MR quantification of hepatic iron (i.e., the liver iron concentration) and give you a step-by-step approach by answering the most pertinent questions. The following article should be more of a manual or guide for every radiologist than a classic review article, which just summarizes the literature. Furthermore, we provide important background information for professional communication with clinicians. The information regarding the physical background is reduced to a minimum. After reading this article, you should be able to perform adequate MR measurements of the LIC with 1.5-T or 3.0-T scanners. KEY POINTS: • MRI is widely accepted as the primary approach to non-invasively determine liver iron concentration (LIC). • This article is a guide for every radiologist to perform adequate MR measurements of the LIC. • When using R2* relaxometry, some points have to be considered to obtain correct measurements-all explained in this article.
['Henninger|Benjamin|B|http://orcid.org/0000-0003-2872-840X', 'Alustiza|Jose|J|', 'Garbowski|Maciej|M|', 'Gandon|Yves|Y|']
D002985:Clinical Protocols D006801:Humans D007501:Iron D019190:Iron Overload D008099:Liver D008279:Magnetic Resonance Imaging D017410:Practice Guidelines as Topic
Iron Liver Magnetic resonance imaging