Pathologic and molecular characterization of Streptococcus dysgalactiae subsp. equisimilis infection in neonatal piglets.
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is an emerging pathogen in animals and humans. Herein, we describe two clinical swine cases of SDSE infection presenting with lameness, neurological signs, or sudden death. Pathological examination indicated suppurative arthritis, encephalitis, and multifocal abscesses in kidney and heart. The β-hemolytic colonies obtained from joint samples of each case were identified as SDSE. The two isolates had low minimum inhibitory concentrations for β-lactams, and they presented the same virulence gene profile (slo-/sagA＋/pSTKP8＋). Molecular analysis by multilocus sequence typing identified the SDSE isolates from cases 1 and 2 as sequence types 315 and 252, respectively.
['Oh|Sang-Ik|SI|', 'Kim|Jong Wan|JW|', 'Jung|Ji-Youl|JY|', 'Chae|Myeongju|M|', 'Lee|Yu-Ran|YR|', 'Kim|Jong Ho|JH|', 'So|ByungJae|B|', 'Kim|Ha-Young|HY|']
D000818:Animals D000831:Animals, Newborn D000900:Anti-Bacterial Agents D008826:Microbial Sensitivity Tests D058885:Multilocus Sequence Typing D013290:Streptococcal Infections D013291:Streptococcus D013552:Swine D013553:Swine Diseases
piglet Streptococcus dysgalactiae subspecies equisimilis multilocus sequence typing microbial sensitivity tests