Severity of coronary artery disease affects prognosis of patients with peripheral artery disease.
It remains unclear whether severity of coronary artery disease (CAD) affects the prognosis of patients with peripheral artery disease (PAD). In this retrospective, multicenter study, we analyzed 537 consecutive patients with symptomatic PAD who underwent both peripheral artery revascularization and coronary angiography (CAG) prior to revascularization. We classified patients into 3 groups based on CAG: no-CAD group, intermediate CAD group (1-2 diseased vessels), and triple-vessel disease (TVD) group. We evaluated clinical outcome including all-cause death, major adverse cardiac events (MACEs), and amputation. The no-CAD, intermediate CAD, and TVD groups comprised 204, 268, and 65 patients, respectively. Mean follow-up duration was 952 ± 497 days. Freedom from any adverse outcome was highest in the no-CAD group and lowest in the TVD group (all-cause death: 86% vs 77% vs 65%, P = .043; MACE: 95% vs 87% vs 78%, P = .044; amputation: 96% vs 92% vs 83%, P = .0015). Severity of CAD affected prognosis of patients with PAD.
['Ishihara|Takayuki|T|', 'Iida|Osamu|O|', 'Tosaka|Atsushi|A|', 'Soga|Yoshimitsu|Y|', 'Sakamoto|Yasunari|Y|', 'Hirano|Keisuke|K|', 'Nanto|Shinsuke|S|', 'Uematsu|Masaaki|M|']
D000368:Aged D000369:Aged, 80 and over D000671:Amputation D016009:Chi-Square Distribution D017023:Coronary Angiography D003324:Coronary Artery Disease D005260:Female D006801:Humans D007383:Intermittent Claudication D007511:Ischemia D007564:Japan D053208:Kaplan-Meier Estimate D023821:Limb Salvage D008297:Male D008875:Middle Aged D058729:Peripheral Arterial Disease D011237:Predictive Value of Tests D012189:Retrospective Studies D012307:Risk Factors D012720:Severity of Illness Index D013997:Time Factors D016896:Treatment Outcome
coronary artery disease prognosis peripheral artery disease