An international effort and use of social media to save a young girl.
BACKGROUND AND OBJECTIVES
A 2-year-old female with neuroblastoma needed In(b-), E- red blood cells (RBCs). No units were available at the blood centre (BC) nor in the rare donor programme member's inventories. BC's Immunohematology Reference Laboratory (IRL) and its marketing department concentrated on recruiting and testing those donors more likely to be antigen negative based on ethnicity.


MATERIALS AND METHODS
The BC's communication plan utilized social and traditional media to assist in the search for In(b-) blood. Media strategies directed donors in the United States (US) and Canada to go to their nearest BC for collection, tagging and testing of units. Two segments from each donation were shipped overnight to the BC's IRL (associated with the patient) for testing. Diluted anti-Inb sera was tested by microtechniques to conserve resources. Additionally, the American Rare Donor Program (ARDP) facilitated the international searches and acted as a liaison to the Food and Drug Administration (FDA).


RESULTS
More than 25 000 people responded to the appeal. Seventy-seven BCs submitted segments from 4197 units. Two donors were In(b-) but E+ and thus not compatible with the patient but were submitted to ARDP for future needs. The prevalence of In(b-) units identified in the search was 0·048%. In total, five known In(b-) donors, two from the US and three from international sources, provided units for this patient.


CONCLUSION
Social media sparked a viral response to the rare blood need. While a match was not found among the units tested, domestic and international searches were able to meet the patient's blood needs.
['Gammon|Richard R|RR|https://orcid.org/0000-0002-1175-9579', 'Tyler|Lisa|L|', 'Alvarez|Harold|H|', 'Benitez|Nancy|N|', 'Nance|Sandra|S|', 'Burton|Angela|A|', 'Delk|Alexander|A|', 'Bright|Frieda|F|', 'Sawh|Dave|D|', 'Forbes|Susan|S|']
D001782:Blood Donors D002170:Canada D002675:Child, Preschool D004912:Erythrocytes D005260:Female D006801:Humans D009447:Neuroblastoma D061108:Social Media D014481:United States
immunohematology RBC antigens and antibodies blood components blood groups donor motivation transfusion-paediatrics