Treatment failure in automated peritoneal dialysis and double-bag continuous ambulatory peritoneal dialysis.
AIM
Automated peritoneal dialysis (APD) and double-bag continuous ambulatory peritoneal dialysis (CAPD) are the two current standard modalities of peritoneal dialysis (PD). Outcomes of these two modalities have not been well described.


METHODS
A single-centre, retrospective review was carried out to compare the treatment failure rate of APD and double-bag CAPD. Treatment failure was a combined endpoint including death and technique failure. Cox regression was used to compare risk (hazard ratio, HR) of treatment failure in APD and CAPD.


RESULTS
There were 121 patients included in this study, 55 with APD and 66 with CAPD. APD patients had significantly lower risk of treatment failure (death and technique failure) than CAPD patients (HR 0.58, 95% confidence interval [CI]: 0.37-0.91, P=0.02). The lower risk of treatment failure in APD compared to CAPD was mainly caused by the significantly lower risk of technique failure (HR 0.30, 95%CI: 0.10-0.93, P=0.04). The mortality rates of the two modalities were not significantly different (HR 0.69, 95%CI: 0.42-1.12, P=0.13).


CONCLUSION
Our data suggest that APD may have lower risk of treatment failure compared with double-bag CAPD. These potential benefits of APD might justify the use of this modality despite its higher cost.
['Katavetin|Pisut|P|', 'Theerasin|Yuwadee|Y|', 'Treamtrakanpon|Worapot|W|', 'Saiprasertkit|Nalinee|N|', 'Kanjanabuch|Talerngsak|T|']
D000368:Aged D000369:Aged, 80 and over D001331:Automation D016009:Chi-Square Distribution D018572:Disease-Free Survival D005260:Female D006801:Humans D053208:Kaplan-Meier Estimate D007674:Kidney Diseases D008297:Male D008875:Middle Aged D015999:Multivariate Analysis D018579:Patient Selection D010530:Peritoneal Dialysis D010531:Peritoneal Dialysis, Continuous Ambulatory D016016:Proportional Hazards Models D012189:Retrospective Studies D018570:Risk Assessment D012307:Risk Factors D013785:Thailand D017211:Treatment Failure
treatment failure automated peritoneal dialysis peritoneal dialysis continuous ambulatory peritoneal dialysis mortality