Findings and Prognostic Value of Contrast-Enhanced Early Magnetic Resonance Imaging After Coil Embolization of Cerebral Aneurysms.
BACKGROUND
Recent studies imply an association between aneurysm wall enhancement (AWE) on contrast-enhanced magnetic resonance imaging and aneurysm rupture. We investigated the prevalence and clinical significance of AWE and enhancement within the aneurysm (inner enhancement [IE]) in coiled aneurysms.


METHODS
We assessed the frequency of AWE and IE after coil embolization on postinterventional magnetic resonance imaging (<6 weeks) in 30 consecutive patients with 33 aneurysms and elucidated the association between enhancement and subsequent aneurysm recurrence or hemorrhage.


RESULTS
AWE and IE occurred in 97% and 36% of cases, respectively. There was no rehemorrhage, and there was no significant association between subsequent reperfusion and AWE (P = 0.200) or IE (P = 0.148) during a median follow-up period of 19 months. The greatest share of IE (8 of 12 aneurysms) was found in incompletely coiled aneurysms with small remnants (P = 0.001).


CONCLUSIONS
AWE after coil embolization cannot be used for recurrence risk stratification owing to its high prevalence. IE is likely to represent contrast inflow in the coiled aneurysm.
['Nikoubashman|Omid|O|', 'Tabrizi|Carolin Molavi|CM|', 'Münstermann|Malte|M|', 'Schubert|Gerrit Alexander|GA|', 'Reich|Arno|A|', 'Wiesmann|Martin|M|', 'Müller|Marguerite|M|']
D003287:Contrast Media D004621:Embolization, Therapeutic D005260:Female D006801:Humans D002532:Intracranial Aneurysm D018810:Magnetic Resonance Angiography D008297:Male D008875:Middle Aged D011379:Prognosis D012008:Recurrence
Coiling Aneurysm Rupture Contrast MRI