Obesity Is Less Frequently Associated with Cognitive Impairment in Elderly Individuals: A Cross-Sectional Study in Yogyakarta, Indonesia.
Obesity is one of the factors associated with cognitive impairment. However, obesity may differently affect cognitive function in different age groups, and scarce data are available from low- and middle-income countries. This cross-sectional study aimed to identify the association between obesity and cognitive impairment among 143 elderly individuals in Yogyakarta. We recorded the sociodemographic factors and some comorbidities, also measured the body mass index as a parameter of obesity, cognitive function using Montreal Cognitive Assessment-Indonesia, mood condition and depression status using geriatric depression scale-short form, as well as the daily life function using Activity of Daily Living and Instrumental Activity of Daily Living. After adjustment for the sociodemographic and comorbidities, we found that subjects with older age were more likely to have cognitive impairment (odds ratio [OR] 3.544, 95%CI: 1.36-9.22, p < 0.01) and compared with elderly individuals with normal weight, obese elderly individuals were 40% less likely to have cognitive impairment (OR 0.604, 95%CI: 0.39-0.95, p < 0.05). This study suggests that obesity in elderly individuals is less frequently associated with cognitive impairment. These findings support the reverse causation mechanism related to body mass index (BMI) and cognitive impairment in low/middle-income countries.
['Vidyanti|Amelia Nur|AN|0000-0002-2741-2983', 'Hardhantyo|Muhammad|M|0000-0003-4786-4925', 'Wiratama|Bayu Satria|BS|0000-0001-9965-778X', 'Prodjohardjono|Astuti|A|', 'Hu|Chaur-Jong|CJ|']
D000367:Age Factors D000368:Aged D000369:Aged, 80 and over D015992:Body Mass Index D060825:Cognitive Dysfunction D003430:Cross-Sectional Studies D005260:Female D015577:Geriatric Assessment D006801:Humans D007214:Indonesia D008297:Male D000073216:Mental Status and Dementia Tests D008875:Middle Aged D009765:Obesity
obesity cognitive impairment elderly Indonesia body mass index