Outer membrane vesicles in service as protein shuttles, biotic defenders, and immunological doppelgängers.
Characterization of host microbial interactions typically occurs on the cellular or protein level. Recently, a more thorough and accurate appreciation of cellular interactions has come into better focus with improved understanding of membrane vesicles (OMV). While OMVs are documented primarily in Gram-negative bacteria, certain Gram-positive species generate these structures, despite the obvious physical limitations of the cell envelope. Here, we briefly review the current understanding of OMVs in content and function, their role in pathogenesis, and the consequences of somatic cell gene expression on these events.
['Laughlin|Richard C|RC|', 'Alaniz|Robert C|RC|']
D000818:Animals D001419:Bacteria D001424:Bacterial Infections D001426:Bacterial Proteins D002462:Cell Membrane D054884:Host-Pathogen Interactions D006801:Humans D021381:Protein Transport D022161:Transport Vesicles
membrane vesicles bacteria pathogenesis immunity