Survival and glycemic control outcomes among patients with coexisting pancreatic cancer and diabetes mellitus.
Aim
We aimed to determine the effect of diabetes mellitus (DM) on survival in pancreatic cancer and effects of pancreatic cancer on glycemic control in DM.


Materials & methods
Patients with pancreatic cancer from 2007 to 2015, with and without DM, were matched 1:1. We compared characteristics between the groups and assessed 2-year survival with Kaplan-Meier analysis.


Results
In patients with DM, hemoglobin A1c decreased significantly over time (p = 0.01). In survival analysis, 2-year overall survival estimates were 15% (95% CI: 8-24%) for DM patients versus 26% (95% CI: 17-36%) for non-DM patients (p = 0.55). The hazard ratio for matched pairs was 1.15 (95% CI: 0.75-1.77; p = 0.51).


Conclusion
DM did not decrease survival in pancreatic cancer. Pancreatic cancer did not affect glycemic control.
['Karlin|Nina J|NJ|', 'Amin|Shailja B|SB|', 'Kosiorek|Heidi E|HE|', 'Buras|Matthew R|MR|', 'Verona|Patricia M|PM|', 'Cook|Curtiss B|CB|']
survival glycemic control cancer CA 19-9 endocrinology outcomes research pancreas therapy