Congenital Malformations Associated With a Single Umbilical Artery in Twin Pregnancies.
A single umbilical artery (SUA) was identified in 1.5% of twin pregnancies. The presence of a SUA in a twin pregnancy was associated with a 50% incidence of fetal anomalies, many of them complex and severe. The embryology and pathophysiological mechanisms associated with a SUA are reviewed. Aneuploidy is relatively common and should be considered, particularly in the presence of associated anomalies. Fetal growth restriction is frequent and preterm delivery is common.
['Mitchell|Sarah E|SE|', 'Reidy|Karen|K|', 'Da Silva Costa|Fabricio|F|', 'Palma-Dias|Ricardo|R|', 'Cade|Thomas J|TJ|', 'Umstad|Mark P|MP|']
D000328:Adult D000013:Congenital Abnormalities D016208:Databases, Factual D005260:Female D005317:Fetal Growth Retardation D005865:Gestational Age D006801:Humans D007231:Infant, Newborn D008297:Male D011247:Pregnancy D059285:Pregnancy, Twin D047928:Premature Birth D058529:Single Umbilical Artery D014463:Ultrasonography D014469:Umbilical Arteries D055815:Young Adult
single umbilical artery twins fetal anomalies growth restriction