Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis.
OBJECTIVE
Assess the reliability of early erosions in rheumatoid arthritis (EERA) software for quantifying erosive damage to the metacarpophalangeal joints of patients with rheumatoid arthritis (RA).


METHODS
One hundred magnetic resonance image sets from 68 patients with early referral RA were evaluated. Reliability was assessed using 95% limits of agreement and intraclass correlation coefficient (ICC) with 95% CI.


RESULTS
Limits of agreement linearly depended on erosion volume: 0.44× between readers and 0.19× within readers. Interrater ICC was 0.976 (95% CI 0.965-0.984) and intrarater ICC was 0.996 (95% CI 0.994-0.997).


CONCLUSION
EERA is highly reproducible for quantifying erosions in patients with early RA.
['Tomizza|Michael A|MA|', 'Jessome|Matthew A|MA|', 'Barbosa|Joshua|J|', 'Beattie|Karen A|KA|', 'Bensen|William G|WG|', 'Bobba|Raja S|RS|', 'Cividino|Alfred A|AA|', 'Emond|Patrick D|PD|', 'Gordon|Chris|C|', 'Hart|Lawrence|L|', 'Ioannidis|George|G|', 'Koh|Melissa X P|MX|', 'Larché|Maggie|M|', 'Tavares|Ruben|R|', 'Tytus|Stephen|S|', 'Adachi|Jonathan D|JD|']
D000368:Aged D000465:Algorithms D001172:Arthritis, Rheumatoid D018450:Disease Progression D005260:Female D006801:Humans D007091:Image Processing, Computer-Assisted D008279:Magnetic Resonance Imaging D008297:Male D008662:Metacarpophalangeal Joint D008875:Middle Aged D015203:Reproducibility of Results D012720:Severity of Illness Index
METACARPOPHALANGEAL JOINT RHEUMATOID ARTHRITIS MAGNETIC RESONANCE IMAGING JOINT EROSIONS REPRODUCIBILITY OF RESULTS