Sub-Acute Effects of Psilocybin on Empathy, Creative Thinking, and Subjective Well-Being.
Creative thinking and empathy are crucial for everyday interactions and subjective well-being. This is emphasized by studies showing a reduction in these skills in populations where social interaction and subjective well-being are significantly compromised (e.g., depression). Anecdotal reports and recent studies suggest that a single administration of psilocybin can enhance such processes and could therefore be a potential treatment. However, it has yet to be assessed whether effects outlast acute intoxication. The present study aimed to assess the sub-acute effects of psilocybin on creative thinking, empathy, and well-being. Participants attending a psilocybin retreat completed tests of creative (convergent and divergent) thinking and empathy, and the satisfaction with life scale on three occasions: before ingesting psilocybin (N = 55), the morning after (N = 50), and seven days after (N = 22). Results indicated that psilocybin enhanced divergent thinking and emotional empathy the morning after use. Enhancements in convergent thinking, valence-specific emotional empathy, and well-being persisted seven days after use. Sub-acute changes in empathy correlated with changes in well-being. The study demonstrates that a single administration of psilocybin in a social setting may be associated with sub-acute enhancement of creative thinking, empathy, and subjective well-being. Future research should test whether these effects contribute to the therapeutic effects in clinical populations.
['Mason|Natasha L|NL|0000-0001-7115-0389', 'Mischler|Elisabeth|E|', 'Uthaug|Malin V|MV|', 'Kuypers|Kim P C|KPC|0000-0001-7634-3809']
D000328:Adult D003405:Creativity D004645:Empathy D005260:Female D006213:Hallucinogens D006801:Humans D008297:Male D010549:Personal Satisfaction D011562:Psilocybin D013997:Time Factors
psilocybin empathy creativity divergent thinking Convergent thinking life satisfaction