A randomised, controlled trial of rectus sheath bupivacaine and intrathecal bupivacaine, without or with intrathecal morphine, vs. intrathecal bupivacaine and morphine after caesarean section.
We recruited 144 women of whom 131 underwent scheduled caesarean section and were allocated to intrathecal bupivacaine without (46) or with (47) morphine and postoperative rectus sheath bupivacaine; or intrathecal bupivacaine with morphine and postoperative rectus sheath saline (38). We measured postoperative pain with a 10-point numeric rating scale. The mean (SD) areas under the curve for pain on movement during 48 postoperative hours were 273.5 (63.6), 223.8 (80.7) and 223.8 (80.7), respectively, p = 0.008. There was no difference between women who had intrathecal morphine with or without rectus sheath bupivacaine, p = 1. The equivalent values for pain at rest were 160.8 (64.7), 85.8 (79.4) and 82.8 (74.3), respectively, p < 0.001. There was no difference between women who had intrathecal morphine with or without rectus sheath bupivacaine, p = 0.98.
['Lui|M W|MW|', 'Li|T K T|TKT|', 'Lui|F|F|', 'Ong|C Y T|CYT|']
D000328:Adult D000701:Analgesics, Opioid D000773:Anesthesia, Obstetrical D000779:Anesthetics, Local D002045:Bupivacaine D002585:Cesarean Section D005260:Female D006801:Humans D007278:Injections, Spinal D009020:Morphine D009407:Nerve Block D010147:Pain Measurement D010149:Pain, Postoperative D011247:Pregnancy
morphine caesarean section local analgesics postoperative pain control rectus sheath block