MIRIA: a webserver for statistical, visual and meta-analysis of RNA editing data in mammals.
BACKGROUND
Adenosine-to-inosine RNA editing can markedly diversify the transcriptome, leading to a variety of critical molecular and biological processes in mammals. Over the past several years, researchers have developed several new pipelines and software packages to identify RNA editing sites with a focus on downstream statistical analysis and functional interpretation.


RESULTS
Here, we developed a user-friendly public webserver named MIRIA that integrates statistics and visualization techniques to facilitate the comprehensive analysis of RNA editing sites data identified by the pipelines and software packages. MIRIA is unique in that provides several analytical functions, including RNA editing type statistics, genomic feature annotations, editing level statistics, genome-wide distribution of RNA editing sites, tissue-specific analysis and conservation analysis. We collected high-throughput RNA sequencing (RNA-seq) data from eight tissues across seven species as the experimental data for MIRIA and constructed an example result page.


CONCLUSION
MIRIA provides both visualization and analysis of mammal RNA editing data for experimental biologists who are interested in revealing the functions of RNA editing sites. MIRIA is freely available at https://mammal.deepomics.org.
['Feng|Xikang|X|', 'Wang|Zishuai|Z|', 'Li|Hechen|H|', 'Li|Shuai Cheng|SC|']
D000818:Animals D016678:Genome D023281:Genomics D059014:High-Throughput Nucleotide Sequencing D006801:Humans D008322:Mammals D012313:RNA D017393:RNA Editing D017423:Sequence Analysis, RNA D059467:Transcriptome
Webserver Visualization RNA editing Mammal Analysis