Short-Term Improvement in Physical Activity and Body Composition After Supervised Exercise Training Program in Idiopathic Pulmonary Fibrosis.
OBJECTIVE
To examine the effect of participating in a 12-week supervised exercise training (ET) program on physical activity and body composition in patients with idiopathic pulmonary fibrosis (IPF).


DESIGN
Randomized controlled trial assessing physical activity and body composition at baseline, after 12-week intervention, and at 11 months follow-up.


SETTING
Outpatient hospital.


PARTICIPANTS
Patients with IPF (N=34; mean age, 68±8y) recruited for this study; 32 patients completed the 12-week intervention (ET group: n=15; control group: n=17) and 28 patients (14 in each group) reassessed at 11-month follow-up from baseline.


INTERVENTIONS
Participation in a 12-week supervised ET program or regular medical treatment.


MAIN OUTCOME MEASURES
Changes in physical activity levels as measured by the International Physical Activity Questionnaire.


RESULTS
After the 12-week intervention, physical activity levels were significantly increased in the ET group whereas the control group showed a trend toward deterioration (median difference between the groups, 2164MET-min/wk [interquartile range, 1576MET-min/wk]; MET = metabolic equivalent; P<.001). Body composition was also significantly improved in the ET group, whereas the control group showed an opposite trend. At 11-month follow-up, no significant differences were observed between the 2 groups in all variables. The ET group lost most of the achieved improvements in the outcomes and returned to near baseline levels, whereas the control group showed a trend toward worsened outcomes.


CONCLUSIONS
Physical activity and body composition in patients with IPF were improved after a 12-week supervised ET program, although the benefits were not sustained at 11-month follow-up. These results may support the efficacy of participation in supervised ET to improve physical activity and body composition in patients with IPF; however, maintenance strategies are warranted to preserve the improved outcomes.
['Vainshelboim|Baruch|B|', 'Fox|Benjamin Daniel|BD|', 'Kramer|Mordechai Reuven|MR|', 'Izhakian|Shimon|S|', 'Gershman|Evgeni|E|', 'Oliveira|Jose|J|']
D000368:Aged D001823:Body Composition D015444:Exercise D005081:Exercise Therapy D005260:Female D005500:Follow-Up Studies D006801:Humans D054990:Idiopathic Pulmonary Fibrosis D008297:Male D008875:Middle Aged D016896:Treatment Outcome
Exercise Rehabilitation Waist circumference