Dementia with Lewy bodies presenting as probable epileptic seizure.
We discuss the case of an 83-year-old man admitted to the hospital after losing control of his vehicle due to an unexplained episode of altered consciousness. This occurred on a background of multiple similar episodes associated with acute confusion, superimposed on a gradual cognitive decline spanning 6 years. Organic aetiologies for delirium were excluded and CT and MRI of the brain were negative for cerebrovascular accidents or other epileptogenic foci. Electroencephalogram (EEG) was negative for epileptiform activity. A diagnosis of seizure in the setting of dementia with Lewy bodies (DLB) was deemed probable. Subsequent brain single-photon emission computed tomography (SPECT) and flurodeoxy glucose-positron emission tomography (FDG-PET) studies supported the underlying diagnosis of DLB. Acute changes in consciousness or cognition are often related to strokes or seizures in the older person. As illustrated in this case, however, it is important to consider alternative comorbidities that may coexist.
['Tun|Mya Z|MZ|', 'Soo|Wee Kheng|WK|', 'Wu|Kevin|K|', 'Kane|Richard|R|']
D000369:Aged, 80 and over D003937:Diagnosis, Differential D004569:Electroencephalography D006801:Humans D020961:Lewy Body Disease D008297:Male D049268:Positron-Emission Tomography D012640:Seizures D015899:Tomography, Emission-Computed, Single-Photon
dementia, alzheimer’s type epilepsy and seizures geriatric medicine memory disorders (psychiatry)