Comparison of different methods for the extraction of cannabinoids from cannabis.
Cannabis oils, namely concentrated cannabis extracts, are getting plenty of attention because of their therapeutic potential for treatment of patients with cancer, HIV, multiple sclerosis and several other pathologies. Here we propose the use of ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) as alternative methods to the current protocols followed by pharmacists, the only authorized to manipulate standardized Cannabis. A third method, consisting of the use of Tween 20 as surfactant, was considered. Our best extraction methodology for commercial hemp extraction was applied to medicinal cannabis. Here we report the results obtained for 'Eletta campana', 'Carmagnola selezionata', Bediol®, FM2® and Bedrocan®.
['De Vita|Daniela|D|', 'Madia|Valentina Noemi|VN|', 'Tudino|Valeria|V|', 'Saccoliti|Francesco|F|', 'De Leo|Alessandro|A|', 'Messore|Antonella|A|', 'Roscilli|Patrizia|P|', 'Botto|Alfonso|A|', 'Pindinello|Ivano|I|', 'Santilli|Gianluigi|G|', 'Scipione|Luigi|L|http://orcid.org/0000-0002-2006-7005', 'Costi|Roberta|R|http://orcid.org/0000-0002-1314-9029', 'Di Santo|Roberto|R|http://orcid.org/0000-0002-4279-7666']
D002186:Cannabinoids D002188:Cannabis D005591:Chemical Fractionation D008872:Microwaves D015394:Molecular Structure D010936:Plant Extracts D011136:Polysorbates D013501:Surface-Active Agents D014465:Ultrasonics
Cannabis extraction ultrasound-assisted extraction microwave-assisted extraction medicinal cannabis industrial hemp