Allele and genotype frequencies of polymorphisms in cytokine genes in ethnic Russian individuals from Moscow, Russia.
Two hundred and twenty eight ethnic Russian individuals from Moscow, Russia, were genotyped at 14 single nucleotide polymorphisms CCL2 A-2578G; VEGFA C-2578A, G-634C, and C+936T; TNF G+419A and G-308A; IL1A G-889A; IL1RN T+1018C; IL6G-174C and G-572C; IFNG T+874A; IL1B C-511T; IL10 A+1082G; TGFB1 C-509T. Genotypes were determined using real-time polymerase chain reaction with TaqMan probes and polymerase chain reaction followed by melting analysis of dual-labeled probe. Genotype distribution was in accordance with Hardy-Weinberg equilibrium for all studied polymorphisms. Genotype data are available in the Allele Frequencies Net Database under identifier AFND 3367 and the population name "Russia Moscow Cytokine".
['Shadrina|Alexandra|A|', 'Voronina|Elena|E|', 'Zolotukhin|Igor|I|', 'Filipenko|Maxim|M|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D016207:Cytokines D030541:Databases, Genetic D005006:Ethnicity D005260:Female D005787:Gene Frequency D005828:Genetics, Population D005838:Genotype D006801:Humans D008297:Male D008875:Middle Aged D009031:Moscow D011110:Polymorphism, Genetic D012426:Russia D055815:Young Adult
Allele Polymorphism Cytokine Ethnic Russians SNP