Dietary Inflammatory Index and Type 2 Diabetes Mellitus in Adults: The Diabetes Mellitus Survey of Mexico City.
Diet and inflammation are both associated with type 2 diabetes mellitus (T2DM). In the present study, we aimed to assess the relation between the dietary inflammatory index (DII) and the presence of T2DM in Mexican adults participating in the Diabetes Mellitus Survey administered in Mexico City (DMS-MC). The study involved 1174 subjects (48.5% men) between 20-69 years of age. A validated semi-quantitative food frequency questionnaire was employed to evaluate dietary intake and to compute DII. The DII is based on scientific evidence about the association between dietary compounds and six established inflammatory biomarkers. Multivariate logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs) of DII in relation to T2DM. Our results suggest that subjects in the highest quintile of the DII had higher odds of T2DM (OR = 3.02; 95% CI: 1.39, 6.58; p = 0.005) compared to subjects in the lowest quintile of DII scores. Assessing possible effect modification, an association with T2DM was evident when comparing DII quintile 5 to quintile 1 for participants aged ≥ 55 years (OR = 9.77; 95% CI: 3.78, 25.50; p = 0.001). These results suggest that a pro-inflammatory diet is associated with significantly higher odds of T2DM among adult Mexicans.
['Denova-Gutiérrez|Edgar|E|0000-0001-9671-9682', 'Muñoz-Aguirre|Paloma|P|', 'Shivappa|Nitin|N|', 'Hébert|James R|JR|', 'Tolentino-Mayo|Lizbeth|L|0000-0003-2400-8675', 'Batis|Carolina|C|0000-0002-2823-6651', 'Barquera|Simón|S|0000-0003-1854-4615']
D000328:Adult D000368:Aged D015415:Biomarkers D001786:Blood Glucose D016009:Chi-Square Distribution D003430:Cross-Sectional Studies D003924:Diabetes Mellitus, Type 2 D004032:Diet D004034:Diet Surveys D005260:Female D006442:Glycated Hemoglobin A D006801:Humans D007249:Inflammation D018836:Inflammation Mediators D008055:Lipids D016015:Logistic Models D008297:Male D008800:Mexico D008875:Middle Aged D015999:Multivariate Analysis D016017:Odds Ratio D015995:Prevalence D012307:Risk Factors D055815:Young Adult
dietary inflammatory index type 2 diabetes mellitus survey Mexican population obesity