Resistin may be an independent predictor of subclinical atherosclerosis formale smokers.
To investigate whether resistin is associated with early atherosclerosis in male smokers. The present study consecutively enrolled 50 male smokers. Their serum resistin contents were detected with enzyme linked immunosorbent assay (ELISA), and subclinical atherosclerosis indices, including carotid inner middle thickness (IMT) and arterial elasticity indices (C1 and C2), were measured. The association between serum resistin levels and IMT, C1 and C2 were respectively evaluated with the Pearson's correlation coefficient method. The results showed that the serum resistin level had a positive association with IMT (r = 0.307, p = .030), but were both inversely associated with C1 (r = -0.440, p = .001) and C2 (r = -0.381, p = .006). These associations remained significant even after adjustment for cardiovascular confounders. In conclusion, serum resistin concentration was independently associated with early atherosclerosis in male smokers.
['He|Ying|Y|', 'Bai|Xiao-Jun|XJ|', 'Li|Fen-Xia|FX|', 'Fan|Li-Hong|LH|', 'Ren|Jie|J|', 'Liang|Qi|Q|', 'Li|Hong-Bing|HB|', 'Bai|Ling|L|', 'Tian|Hong-Yan|HY|', 'Fan|Fen-Ling|FL|', 'Tian|Gang|G|', 'Ma|Ai-Qun|AQ|', 'Chen|Jinghong|J|']
D001158:Arteries D050197:Atherosclerosis D059168:Carotid Intima-Media Thickness D004548:Elasticity D006801:Humans D008297:Male D008875:Middle Aged D052243:Resistin D012907:Smoking
Resistin atherosclerosis arterial elasticity intima media thickness smoking