Upgrading carbon dioxide by incorporation into heterocycles.
Carbon dioxide is commonly regarded as the primary greenhouse gas, but from a synthetic standpoint can be utilized as an alternative and sustainable C1 synthon in organic synthesis rather than a waste. This results in the production of organic carbonates, carboxylic acids, and derivatives. Recently, CO2 has emerged as an appealing tool for heterocycle synthesis under mild conditions without using stoichiometric amounts of organometallic reducing reagents. This Minireview summarizes recent advances on methodologies for CO2 incorporation into N-, O-, and C-nucleophiles to provide various heterocycles, including cyclic carbamates, benzoxazine-2-one, 4-hydroxyquinolin-2-one, quinazoline-2,4(1 H,3 H)-diones, benzimidazolones, α-alkylidene cyclic carbonate.
['Yu|Bing|B|', 'He|Liang-Nian|LN|']
D002245:Carbon Dioxide D002264:Carboxylic Acids D003500:Cyclization D006571:Heterocyclic Compounds D009584:Nitrogen D010100:Oxygen
carbon dioxide heterocycles catalysis sustainable chemistry synthetic methods