Fabrication of functional PLGA-based electrospun scaffolds and their applications in biomedical engineering.
Electrospun PLGA-based scaffolds have been applied extensively in biomedical engineering, such as tissue engineering and drug delivery system. Due to lack of the recognition sites on cells, hydropholicity and single-function, the applications of PLGA fibrous scaffolds are limited. In order to tackle these issues, many works have been done to obtain functional PLGA-based scaffolds, including surface modifications, the fabrication of PLGA-based composite scaffolds and drug-loaded scaffolds. The functional PLGA-based scaffolds have significantly improved cell adhesion, attachment and proliferation. Moreover, the current study has summarized the applications of functional PLGA-based scaffolds in wound dressing, vascular and bone tissue engineering area as well as drug delivery system.
['Zhao|Wen|W|', 'Li|Jiaojiao|J|', 'Jin|Kaixiang|K|', 'Liu|Wenlong|W|', 'Qiu|Xuefeng|X|', 'Li|Chenrui|C|']
D057005:Bioengineering D016503:Drug Delivery Systems D055664:Electrochemical Techniques D019344:Lactic Acid D011100:Polyglycolic Acid D000077182:Polylactic Acid-Polyglycolic Acid Copolymer D054457:Tissue Scaffolds
Electrospun Applications Biomedical engineering Tissue engineering Drug delivery PLGA