microRNA Target Prediction.
microRNAs are short RNAs that reduce gene expression by binding to their targets. Computational predictions indicate that all human genes may be regulated by microRNAs, with each microRNA possibly targeting thousands of genes. Commonly used software will produce a prohibitive number of predicted targets for each microRNA. Here I describe procedures that refine these predictions by integrating available software and expression data from experiments available online. These procedures are tailored to experiments where predicting true targets is more important than detecting all putative targets.
['Ritchie|William|W|']
D020413:3' Untranslated Regions D000465:Algorithms D000818:Animals D020029:Base Pairing D001483:Base Sequence D001665:Binding Sites D019295:Computational Biology D030541:Databases, Genetic D005786:Gene Expression Regulation D006801:Humans D035683:MicroRNAs D012045:Regulatory Sequences, Nucleic Acid D012984:Software
microRNA Target genes microRNA expression