Nonconvulsive status epilepticus following rotavirus gastroenteritis in two pediatric patients.
BACKGROUND
Nonconvulsive status epilepticus (NCSE) comprises a range of conditions in which prolonged electrographic seizures result in nonconvulsive clinical symptoms. An understanding of NCSE is especially important in emergency care. Among the various causes of NCSE, an infectious etiology has been rarely reported to date.


CASE REPORTS
We report two pediatric cases of rotavirus gastroenteritis complicated by NCSE. In both cases, bilateral rhythmic delta activity (2.5-3 Hz) with occipital predominance fluctuated with the patient's consciousness level. The paroxysmal waves disappeared completely and consciousness immediately and remarkably improved after intravenous midazolam infusion. The patients remained alive 10 and 2 years, respectively, after short-term oral anticonvulsant administration, with no epileptic seizures.


CONCLUSION
The etiology of NCSE was identical and the clinical presentations were analogous in the two patients. The seizure semiology differed from that in benign convulsion with gastroenteritis. NCSE was considered the prominent cause of neurological symptoms; however, the pathogenic mechanism remains unclear, including the coexistence of acute encephalopathy.
['Hirata|Ko|K|', 'Sugawara|Yuji|Y|', 'Hoshino|Ai|A|', 'Takeda|Sayaka|S|', 'Kumada|Satoko|S|', 'Hasegawa|Takeshi|T|']
Nonconvulsive status epilepticus Rotavirus Acute encephalopathy Convulsions with mild gastroenteritis