Five cases of acute Zika virus infection in French women of reproductive age returning from Central and South America.
INTRODUCTION
The favorable season for Aedes albopictus circulation has started in Europe and may lead to autochthonous transmission of Zika virus. Health care providers should be familiar with evocative clinical presentations and able to give updated information to women of reproductive age infected by Zika virus.


OBSERVATIONS
We report five laboratory-confirmed Zika virus infections imported to metropolitan France from Central and South America between January and April, 2016. The five young women were not connected and not pregnant; common presentation combined a rash with persistent arthralgia. Zika virus was identified by RT-PCR from serum or urines, between two and eight days after the onset of the symptoms.


CONCLUSION
As the duration of potential materno-foetal infectivity is still unknown, we were unable to answer with certitude to the patients' questions about the time interval to respect before attempting a pregnancy: one of them became pregnant one month after the diagnosis.
['Penot|P|P|', 'Balavoine|S|S|', 'Leplatois|A|A|', 'Brichler|S|S|', 'Leparc-Goffart|I|I|', 'Alloui|A-C|AC|', 'Flusin|O|O|', 'Guilleminot|J|J|', 'Amellou|M|M|', 'Molina|J-M|JM|']
D000208:Acute Disease D000328:Adult D002489:Central America D005076:Exanthema D005260:Female D005602:France D006801:Humans D016133:Polymerase Chain Reaction D060728:Reproductive Health D013020:South America D014195:Travel D000071244:Zika Virus D000071243:Zika Virus Infection
Zika virus Imported viral disease Mother to child transmission Sexually transmitted infections Vector-borne infections