Comparative study on Artemisia halodendron Turcz. and its two related plants by GC-MS analysis and protective effect against carbon tetrachloride-induced hepatotoxicity in mice.
A rapid method had been used for comparative study on Artemisia halodendron Turcz. and its two related plants by gas phase-mass spectrometry (GC-MS). The comparison of the volatile oils obtained in three plants by GC-MS were similar in 20 compositions. However, n-Hexadecanoic acid (10.40%), Biphenyl (7.867%) and 9,12-Octadecadienoic acid (7.25%) were the predominant in the volatile oils of A. halodendron Turcz., whereas these constituents did not exist in the other two plants. And the study investigated the effect of three plants against CCl4-induced hepatotoxicity in mice. 70% ethanol extracts of A. halodendron Turcz. showed weaker protective effect than the other two plants. It suggested that they provide a basis for the identification of the A. halodendron Turcz. from the other two plants and the ethanol extract from three plants exerted a protecting effect against hepatotoxicity.
['Wang|Yayu|Y|', 'Lou|Lu|L|', 'Wang|Jing|J|', 'Lu|Jincai|J|', 'Li|Jing|J|', 'Jia|Lingyun|L|']
D000818:Animals D019306:Artemisia D001713:Biphenyl Compounds D002251:Carbon Tetrachloride D056486:Chemical and Drug Induced Liver Injury D008401:Gas Chromatography-Mass Spectrometry D019787:Linoleic Acid D008297:Male D051379:Mice D009822:Oils, Volatile D020011:Protective Agents
Artemisia halodendron Turcz. GC-MS hepatoprotective