Properties of hydrolyzed guar gum fermented in vitro with pig fecal inocula and its favorable impacts on microbiota.
In order to identify an appropriate substitute for antibiotic use in livestock production, this study investigates the fermentation of guar gum and its low molecular weight hydrolyzed derivatives (GMLP-1, 1-10 kDa; GMLP-2, < 1 kDa) in pig fecal cultures and the associated effects on the intestinal microbiota. Both the non-hydrolyzed guar gum and GMLP were quickly utilized by fecal microbiota. GMLP-2 showed the most rapid SCFA-producing activity and produced higher concentrations of lactate, acetate, and propionate. However, GMLP-1 showed the highest yield of total SCFAs and butyrate. Both the guar gum and GMLP groups improved the abundance of Clostridium sensu stricto 1 and Bifidobacterium, but the most significant enhancement was observed with GMLP-1. This study showed that by associating with its chemical structure, GMLP-1 can be utilized to direct a targeted promotion of the intestinal microbiota and may offer the most favorable effects in livestock production.
['Fu|Xiaodan|X|', 'Wei|Xinyi|X|', 'Xiao|Mengshi|M|', 'Han|Zhenlian|Z|', 'Secundo|Francesco|F|', 'Mou|Haijin|H|']
D000818:Animals D004043:Dietary Fiber D005243:Feces D005260:Female D005685:Galactans D000069196:Gastrointestinal Microbiome D008351:Mannans D053149:Plant Gums D013552:Swine
Fecal microbiota Bifidobacteria Butyrogenic effect Low-molecular weight hydrolyzed guar gum Non-digestible carbohydrates Short-chain fatty acid