Isolation of Human Mesenchymal Stem Cells for Studying ErbB Receptor Signaling.
ErbB receptor signaling plays pivotal roles in tumorigenesis, cancer development, and drug resistance. A better understanding of ErbB signaling is required to achieve better clinical outcomes in cancer treatment. With increasing evidence showing the link between human mesenchymal stem cells (MSCs) and cancer, there is a growing interest in studying the role of ErbB receptor signaling in the regulation of MSCs. For this purpose, obtaining quality primary human MSCs is of great importance. This chapter describes the method of isolating primary human MSCs, aiming to offer researchers of this field a useful tool.
['Chen|Chao|C|', 'Jiang|Hongxing|H|']
D015415:Biomarkers D002469:Cell Separation D002499:Centrifugation, Density Gradient D066246:ErbB Receptors D006801:Humans D059630:Mesenchymal Stem Cells D015398:Signal Transduction
Isolation Mesenchymal stem cells