A novel method for flap delay vacuum assisted flap delay: an experimental study in rabbits.
Flaps are the workhorse of plastic surgery practice. The delay procedures have been defined to prevent flap necrosis. The golden standard method of delay is a surgical delay. On the other hand, a major drawback of surgical delay is two sessions of surgery. Efforts have been made to omit one session and increase the patient safety and decrease the costs. The writer's aim was to evaluate the effects of topical negative pressure, applied prior to flap elevation, on flap survival, perfusion and compare the results with the surgical delay. In a rabbit random flap model, prior to elevation, the writers used a topical negative pressure system on the lateral thoracic region of, for induction of delay and compared the results with surgical delay and the control group. The total and necrotic flap areas, necrosis ratio, histomorphometric vascular density, immunohistochemical evaluation of neovascularization (CD31/CD34), Laser Doppler images and computerized tomography contrast uptake were used to compare the groups. In all of the parameters, the vacuum assisted flap delay was equivalent to surgical delay. Both were superior to non-delayed flaps. Control group had 65.56 ± 18.02% flap necrosis rate, while Surgical Delay group had 37.31 ± 30.74% and Vacuum Assisted Flap Delay group had 19.58 ± 27.35%. Vacuum Assisted Flap Delay did not require an extra operation for the delay procedure. The mechanism of action in the vacuum-assisted flap delay is unclear. The clinical significance should be studied further. However, vacuum assisted flap delay seems to be a promising method in the clinical setting.
['Aydin|Osman Enver|OE|https://orcid.org/0000-0002-5823-2774', 'Algan|Said|S|', 'Tan|Onder|O|https://orcid.org/0000-0002-5706-0069', 'Demirci|Elif|E|', 'Keles|Osman N|ON|https://orcid.org/0000-0001-7740-8248', 'Kantarci|Abdulmecit|A|']
D000818:Animals D000072226:Computed Tomography Angiography D006085:Graft Survival D017078:Laser-Doppler Flowmetry D023421:Models, Animal D009336:Necrosis D054843:Negative-Pressure Wound Therapy D018919:Neovascularization, Physiologic D011817:Rabbits D013524:Surgical Flaps
flap delay vacuum assisted flap delay Topical negative pressure