Enzyme Responsive Inverse Opal Hydrogels.
Structured color in nature is controlled by nano- and micro-structured interfaces giving rise to a photonic bandgap. This study presents a biomimetic optical material based on polymeric inverse opals that respond to enzyme activity. Polymer colloids provide a template in which acryloyl-functionalized poly(ethylene glycol) is integrated; dissolution of the colloids leads to a hydrogel inverse opal that can be lithographically patterned using transfer printing. Incorporating enzyme substrates within the voids provides a material that responds to the presence of proteases through a shift in the optical properties.
['Pei|Yi|Y|', 'Molley|Thomas G|TG|', 'Kilian|Kristopher A|KA|https://orcid.org/0000-0002-8963-9796']
D001672:Biocompatible Materials D040761:Biomimetic Materials D003102:Colloids D003116:Color D020100:Hydrogels D000068897:Iridescence D008855:Microscopy, Electron, Scanning D049329:Nanostructures D010447:Peptide Hydrolases D017785:Photons D011092:Polyethylene Glycols D011108:Polymers D019904:Polymethyl Methacrylate D011327:Printing
enzymes hydrogel biodegradable biomaterials biomimetic materials