Calculating Gamma Camera Uniformity Parameters: Beyond the Vendor-specific Protocol.
Objectives
The aim of this study was to develop and verify a personal computer-based software tool for calculating uniformity indices of gamma camera.


Materials and Methods
The program was developed in MATLAB R2013b under Microsoft Windows operating system. Noise-less digital phantoms with known uniformity parameters were used to verify the accuracy of the program. Two hundred and forty-four Co-57 flood source images were acquired on Symbia T6 and Discovery nuclear medicine/computed tomography 670. The uniformity indices of these images were determined with their respective vendor's software and also by the tool developed. Bland-Altman plots were used for measuring the agreements between the developed program and the vendor's program for the calculation of uniformity indices.


Results
The tool for calculating uniformity indices was found to be accurate. Uniformity indices measured with the tool revealed a very good correlation with vendor's software based on Bland-Altman analysis, as almost all measurements were within the ±2 standard deviation range.


Conclusion
The software tool for calculation of uniformity indices is accurate, and the uniformity indices calculated by it are in agreement with uniformity indices calculated by the vendor's software.
['Pandey|Anil Kumar|AK|', 'Sharma|Param Dev|PD|', 'Kumar|Jay Prakash|JP|', 'Saroha|Kartik|K|', 'Patel|Chetan|C|', 'Bal|Chandra Sekhar|CS|', 'Kumar|Rakesh|R|']
Gamma camera uniformity personal computer-based software MATLAB Co-57 flood source Bland–Altman analysis Digital Imaging and Communications in Medicine National Electrical Manufacturers’ Assosciation