Neurocognitive, neuropsychiatric, and neurological outcomes associated with phenylalanine hydroxylase deficiency: Assessment considerations for nurse practitioners.
PURPOSE
The purpose of this article is to review literature for neurocognitive, neuropsychiatric, neurological complications associated with phenylalanine hydroxylase (PAH) deficiency. The goal is to familiarize nurse practitioners with treatment and monitoring guidelines for persons living with the disorder.


CONCLUSIONS
Appropriate treatment can maximize neurocognitive and neuropsychiatric outcomes.


PRACTICE IMPLICATIONS
Nurse practitioners can help persons with PAH deficiency through education and providing appropriate referrals and by supporting disease-specific treatment.
['Lowe|Tracy B|TB|0000-0003-1115-1405', 'DeLuca|Jane|J|0000-0003-0600-9500', 'Arnold|Georgianne|G|0000-0003-2758-0407']
D004522:Educational Status D006801:Humans D009722:Nurse Practitioners D010649:Phenylalanine D010661:Phenylketonurias
phenylalanine hydroxylase deficiency neurocognitive complications phenylketonuria psychological complications (PKU or PAH deficiency)