Gadofosveset trisodium-enhanced MR angiography for detection of lower gastrointestinal bleeding.
The purpose of our study is to determine if Gadofosveset trisodium-enhanced magnetic resonance angiography (MRA) could be used for detection and localization of acute lower gastrointestinal (LGI) bleed. Four patients underwent MRA (4 females, mean age of 65 years) for suspected LGI bleeding. MRA detected an active rectal bleed in one patient. All other patients did not demonstrate active bleeding and these true negatives were confirmed by computed tomography angiography, endoscopy, and tagged-red blood cell scan or digital subtraction angiography. Preliminary results suggest that MRA may serve as an alternative technique for detecting acute LGI bleeding when nuclear scintigraphy is unavailable or in the younger radiosensitive population but further investigation in a larger cohort is required.
['Hanna|Robert F|RF|', 'Browne|William F|WF|', 'Khanna|Lauren G|LG|', 'Prince|Martin R|MR|', 'Hecht|Elizabeth M|EM|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D015901:Angiography, Digital Subtraction D003287:Contrast Media D005260:Female D005682:Gadolinium D006471:Gastrointestinal Hemorrhage D006801:Humans D018810:Magnetic Resonance Angiography D008875:Middle Aged D009942:Organometallic Compounds
MR angiography Gastrointestinal bleeding Bowel imaging Gadolinium chelate agents MRI