Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico.
BACKGROUND
Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013.


METHODS
Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment.


RESULTS
LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in the treated clusters until 18 (immature and adult stage indices) and 24 months (adult indices only) post-intervention.


CONCLUSIONS
These safe, simple affordable vector control tools were well-accepted by study participants and are potentially suitable in many regions at risk from dengue worldwide.
['Che-Mendoza|Azael|A|', 'Guillermo-May|Guillermo|G|', 'Herrera-Bojórquez|Josué|J|', 'Barrera-Pérez|Mario|M|', 'Dzul-Manzanilla|Felipe|F|', 'Gutierrez-Castro|Cipriano|C|', 'Arredondo-Jiménez|Juan I|JI|', 'Sánchez-Tejeda|Gustavo|G|', 'Vazquez-Prokopec|Gonzalo|G|', 'Ranson|Hilary|H|', 'Lenhart|Audrey|A|', 'Sommerfeld|Johannes|J|', 'McCall|Philip J|PJ|', 'Kroeger|Axel|A|', 'Manrique-Saide|Pablo|P|']
D000330:Aedes D000818:Animals D016000:Cluster Analysis D003153:Community Health Services D003715:Dengue D003716:Dengue Virus D004197:Disease Reservoirs D007722:Health Knowledge, Attitudes, Practice D006801:Humans D057148:Insecticide-Treated Bednets D007306:Insecticides D008800:Mexico D009032:Mosquito Control D010342:Patient Acceptance of Health Care D012621:Seasons D018571:Sentinel Surveillance D014504:Urban Health D014881:Water Supply
Targeted treatment Dengue Control Mexico LLIS Aedes aegypti