Seroprevalence and risk factors of Coxiella burnetii infection among high-risk population in center of Iran, a neglected health problem.
In order to evaluate the prevalence of antibodies against phase I and II antigens of Coxiella Burnetii and to identify related risk factors among high-risk groups in the center of Iran, a serological survey was performed in Isfahan County. In a cross-sectional study, 401 sera were collected from slaughterhouse workers, butchers, farmers and veterinarians in spring 2015. Samples were tested for specific immunoglobulin G (IgG) antibodies against phase I and II of C. burnetii by indirect immunofluorescence assay. A checklist was fulfilled to document demographic information. Univariate analysis and multivariable binary logistic regression model were used to analyze data. IgG antibodies against phases I and II of C. burnetii were detected in 19% and 36.9% of participants, respectively. The overall seropositivity (IgG against phase I and/or II) was 43.1%. The present study shows a high seroprevalence of C. burnetii infection among high-risk population in center of Iran. It is suggested to carry out occupational health monitoring programs for individuals who may be exposed to C. burnetii.
['Nokhodian|Zary|Z|', 'Ataei|Behrooz|B|', 'Moradi|Abdolreza|A|', 'Yaran|Majid|M|', 'Hoseini|Shervin Gaffari|SG|', 'Feizi|Awat|A|', 'Sherkat|Roya|R|']
D000293:Adolescent D000328:Adult D000368:Aged D000369:Aged, 80 and over D000822:Animal Husbandry D000818:Animals D000907:Antibodies, Bacterial D016997:Coxiella burnetii D003430:Cross-Sectional Studies D005260:Female D019084:Fluorescent Antibody Technique, Indirect D019649:Food Industry D006801:Humans D007492:Iran D008297:Male D008875:Middle Aged D015995:Prevalence D011778:Q Fever D012307:Risk Factors D016036:Seroepidemiologic Studies D011795:Surveys and Questionnaires D018634:Veterinarians D055815:Young Adult
Seroprevalence High-risk population Iran C. burnetii