Synthesis of bio-functional nanoparticles from sono-responsive amino acids using high frequency ultrasound.
A simple, one-pot high frequency ultrasonication (490 kHz) methodology to convert hydrophobic and amphipathic amino acids into nanostructures was investigated. The approach involved the oxidative coupling of aromatic amino acids (phenylalanine and tryptophan) in aqueous solutions to form high molecular weight dimers and oligomers. The role of cavitation bubble surface and ultrasonic power to trigger the out-of-equilibrium self-assembly of dimers and trimers to spherical and uniform nanostructures with controlled size has been discussed. The synthesized particles exhibited fluorescence in blue, green and red spectral regions and a strong antioxidant activity.
['Bhangu|Sukhvir Kaur|SK|', 'Ashokkumar|Muthupandian|M|', 'Cavalieri|Francesca|F|']
D005511:Food Handling D053758:Nanoparticles D010649:Phenylalanine D013057:Spectrum Analysis D014364:Tryptophan D000069453:Ultrasonic Waves
Nanoparticles Ultrasound Phenylalanine Tryptophan Self-assembly