PGx: Putting Peptides to BED.
Every molecular player in the cast of biology's central dogma is being sequenced and quantified with increasing ease and coverage. To bring the resulting genomic, transcriptomic, and proteomic data sets into coherence, tools must be developed that do not constrain data acquisition and analytics in any way but rather provide simple links across previously acquired data sets with minimal preprocessing and hassle. Here we present such a tool: PGx, which supports proteogenomic integration of mass spectrometry proteomics data with next-generation sequencing by mapping identified peptides onto their putative genomic coordinates.
['Askenazi|Manor|M|', 'Ruggles|Kelly V|KV|', 'Fenyö|David|D|']
D030562:Databases, Protein D020869:Gene Expression Profiling D023281:Genomics D006801:Humans D013058:Mass Spectrometry D009363:Neoplasm Proteins D010449:Peptide Mapping D040901:Proteomics D020539:Sequence Analysis, Protein
proteomics proteogenomics proteogenomic mapping