Useful parameters to predict the presence of detrusor overactivity in male patients with lower urinary tract symptoms.
AIMS
This study aimed to identify the easily obtainable parameters that predict the presence of detrusor overactivity (DO) in male patients with lower urinary tract symptoms (LUTS), because urodynamic studies cannot be performed in all cases.


METHODS
A total of 605 treatment-naïve men with non-neurogenic LUTS who underwent subjective and objective evaluations were retrospectively reviewed. We divided patients into two groups (the DO and the non-DO group) according to the presence or absence of DO as determined by urodynamic data and compared the clinical parameters between the two groups to identify clinical signs associated with DO.


RESULTS
Of the 605 patients with a mean age of 69.8 years and a mean prostate volume of 45.4 mL, 319 (52.7%) had DO, while DO was not detected in 286 (47.3%). Men with DO were significantly older and had greater prostate volume, longer intravesical prostatic protrusion (IPP), higher international prostate symptom score, higher overactive bladder symptom score (OABSS), smaller bladder capacity, and higher bladder outlet obstruction than those without DO. In a multivariate logistic regression analysis, higher OABSS-urgency subscore and OABSS-urgency urinary incontinence (UUI) subscore and longer IPP were significant predictive signs of DO. Receiver operating characteristic curve analysis identified 3 points, 1 point, and 8.0 mm as the optimal cut-off values for OABSS-urgency subscore, OABSS-UUI subscore, and IPP, respectively, for the diagnosis of DO.


CONCLUSIONS
Higher OABSS-urgency subscore, higher OABSS-UUI subscore, and longer IPP were found to be useful parameters to predict the presence of DO in male patients with LUTS.
['Matsukawa|Yoshihisa|Y|0000-0001-7823-2600', 'Majima|Tsuyoshi|T|0000-0003-2139-9041', 'Ishida|Shohei|S|', 'Funahashi|Yasuhito|Y|', 'Kato|Masashi|M|', 'Gotoh|Momokazu|M|']
D000368:Aged D006801:Humans D059411:Lower Urinary Tract Symptoms D008297:Male D008875:Middle Aged D011467:Prostate D011470:Prostatic Hyperplasia D012189:Retrospective Studies D053201:Urinary Bladder, Overactive D014549:Urinary Incontinence D014563:Urodynamics
detrusor overactivity lower urinary tract symptoms intravesical prostatic protrusion overactive bladder symptom score