Intracranial dural based marginal zone MALT-type B-cell lymphoma: a case - Based update and literature review.
OBJECTIVES
Dural based Marginal Zone MALT-type B-Cell Lymphoma (MZBCL) is an intracranial tumor that can mimicking meningioma both from a clinical and a radiological point of view. A standard treatment protocol is still lacking. Aim of the present work is to provide an update of the present literature regarding this rare neoplasia.


PATIENTS AND METHODS
We report the case of a patient with a dural-based lesion mimicking a meningioma of the tentorium. After surgical treatment, the diagnosis was of MZBCL. A literature review is performed to highlight the typical characteristics of this rare intracranial lesion and to define the best therapeutic approach.


RESULTS
Literature review included 38 articles describing 126 cases of intracranial dural-based MZBCL. No clinical trial has been found. Clinical and histopathological features are properly collected to provide a guide for future cases. Different treatment options have been attempted. Combination of surgery with adjuvant radiation therapy is the most used option.


CONCLUSIONS
MZBCL should be considered in differential diagnosis for dural-based intracranial lesion. Surgery followed by radiation therapy is the most reported treatment. As a consequence of the rarity of this disease, of its indolent progression and of the lack of adequate follow-up, it is not possible to define it is the best treatment option.
['La Rocca|G|G|', 'Auricchio|A M|AM|', 'Mazzucchi|E|E|https://orcid.org/0000-0001-9469-0791', 'Ius|T|T|', 'Della Pepa|G M|GM|', 'Altieri|R|R|', 'Pignotti|F|F|', 'Gessi|M|M|', 'De Santis|V|V|', 'Zoia|C|C|', 'Sabatino|G|G|']
Dural-based lesion radiation therapy differential diagnosis cerebral lymphoma