A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs.
The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-β-D-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.
['Jang|Sung Wan|SW|', 'Suh|Won Se|WS|', 'Kim|Chung Sub|CS|', 'Kim|Ki Hyun|KH|', 'Lee|Kang Ro|KR|']
D000972:Antineoplastic Agents, Phytogenic D045744:Cell Line, Tumor D002855:Chromatography, Thin Layer D006027:Glycosides D006801:Humans D009682:Magnetic Resonance Spectroscopy D000432:Methanol D009369:Neoplasms D010636:Phenols D016339:Spectrometry, Mass, Fast Atom Bombardment D031992:Spiraea
Phenolic glycoside Spiraea prunifolia var. simpliciflora Cytotoxicity