Burden of skin disease and associated socioeconomic status in Asia: A cross-sectional analysis from the Global Burden of Disease Study 1990-2017.
Introduction
Skin diseases have a significant global impact on quality of life, mental health, and loss of income. The burden of dermatologic conditions and its relationship with socioeconomic status in Asia is currently not well understood.


Methods
We selected Global Burden of Disease Study datasets to analyze disability-adjusted life years (DALYs) in 50 Asian countries, including Central Asia, northern Asia, eastern Asia, western Asia, southeastern Asia, and southern Asia, between 1990 and 2017. We compared DALYs to the socioeconomic status using the sociodemographic index and gross domestic product per capita of a country. Statistical analysis was performed using Pearson's correlation.


Results
Some countries had higher or lower than expected age-standardized DALY rates of skin diseases. Asian countries, especially high-income countries, had a high burden of inflammatory dermatoses, including acne, alopecia areata, atopic dermatitis, contact dermatitis, decubitus ulcers, psoriasis, pruritus, and seborrheic dermatitis. The burden of infectious dermatoses was greater in low-income Asian countries. The burden of skin cancer in Asia was relatively low.


Conclusion
There is a high burden of skin disease, especially inflammatory conditions, in Asian countries, but the burden of individual dermatoses in Asia varies by country and socioeconomic status. DALYs can potentially serve as a purposeful measure for directing resources to improve the burden of skin disease in Asia.
['Urban|Katelyn|K|', 'Chu|Sherman|S|', 'Giesey|Rachel L|RL|', 'Mehrmal|Sino|S|', 'Uppal|Prabhdeep|P|', 'Delost|Maria E|ME|', 'Delost|Gregory R|GR|']
socioeconomic status disability-adjusted life years (DALYs) acne alopecia atopic dermatitis psoriasis pruritus skin cancer AA, Alopecia areata DALYs, disability-adjusted life years GBD, Global Burden of Disease GDP, gross domestic product Global Burden of Disease Study (GBD) database NMSC, nonmelanoma skin cancer SDI, sociodemographic index age-standardized prevalence rates basal cell carcinoma global medicine gross domestic product (GDP) per capita infectious disease itch leishmaniasis melanoma nonmelanoma skin cancer (NMSC) scabies squamous cell carcinoma syphilis tuberculosis urticaria viral skin diseases