Planar chiral dialkoxysilane: introduction of inherent chirality and high reactivity in conventional achiral alkene.
A simple eight-membered dialkoxysilane (E)-1 prepared from 2-pentene-1,5-diol, showed remarkably stable planar chirality along with high reactivity toward epoxidation, Diels-Alder reaction, and cycloaddition reaction with azide.
['Tomooka|Katsuhiko|K|', 'Miyasaka|Shouji|S|', 'Motomura|Shougo|S|', 'Igawa|Kazunobu|K|']
chirality dialkoxysilanes alkenes cyclic molecules stereoselective transformations