Association of pulse synchronous tinnitus and sigmoid sinus wall abnormalities in patients with idiopathic intracranial hypertension.
PURPOSE
Pulse synchronous tinnitus (PT) is common in patients with idiopathic intracranial hypertension (IIH) and in those with sigmoid sinus wall abnormalities (SSWAs). Although patients with SSWAs and IIH share many clinical features, the incidence of SSWAs in patients with IIH and its relationship to PT in this cohort is less well established. The purpose of this study is to assess the incidence of SSWAs in patients with IIH and PT, and to determine if there is an association between SSWAs and PT in this population.


MATERIALS AND METHODS
Prospective computed tomography (CT) study of adults with IIH. Subjective PT was correlated with presence or absence of SSWAs on CT.


RESULTS
22 subjects were enrolled and 14 subsequently underwent CT. The incidence of SSWAs was significantly higher in subjects with PT than without (70% vs. 0%, p = 0.02). Mean age, BMI and opening pressures did not differ between those with and without SSWAs or PT.


CONCLUSIONS
There is a high incidence of SSWAs in subjects with IIH and PT. These findings support an association between SSWAs and PT, and implicate SSWAs as a possible cause of, or contributing factor to, PT in patients with IIH. Patients with IIH and PT that does not resolve with reducing intracranial pressure should undergo diagnostic CT and consider treatment of a SSWA if present.
['Kline|Neila L|NL|', 'Angster|Kristen|K|', 'Archer|Erica|E|', 'Raghavan|Prashant|P|', 'Morales|Robert E|RE|', 'Mathews|Michaela K|MK|', 'Eisenman|David J|DJ|']
D000328:Adult D003392:Cranial Sinuses D005260:Female D006801:Humans D019586:Intracranial Hypertension D008297:Male D008875:Middle Aged D011446:Prospective Studies D014012:Tinnitus D014057:Tomography, X-Ray Computed D055815:Young Adult
Sigmoid sinus wall abnormalities Idiopathic intracranial hypertension Pulsatile tinnitus