Antiphospholipid Syndrome On Cloud (APSOnCloud): web-based monitoring of oral anticoagulation.
Antiphospholipid Syndrome (APS) is an autoimmune disease characterized by recurrent thromboses and fetal losses with the presence of antiphospholipid antibodies. The main treatment to prevent recurrent thrombotic events is oral anticoagulation with vitamin K antagonist (VKA), which requires frequent monitoring and dosage adjustments. Outpatient anticoagulation monitoring has its limitations, such as patients spending long hours between the testing procedure and waiting for the results to be adjusted. To optimize this adjustment and to improve APS patients-doctors relationship, we developed a website to help monitor APS patients, called Antiphospholipid Syndrome On Cloud or APSOnCloud. To test it, since March 2014 to March 2016, we registered 20 patients with APS that have inserted 132 international normalized ratio (INR) values. Sixty two percent were out of range and it took on average 7 hours for the doctor in charge to adjust these values. The mean time in therapeutic range was 58.1%. Our preliminary experience in monitoring VKA oral anticoagulation on APSOnCloud suggests that patients with APS might benefit from this web-based monitoring.
['Nogueira|F|F|', 'Signorelli|F|F|', 'Levy|R A|RA|']
D000284:Administration, Oral D000925:Anticoagulants D016736:Antiphospholipid Syndrome D001777:Blood Coagulation D000067917:Cloud Computing D003936:Diagnosis, Computer-Assisted D016903:Drug Monitoring D004360:Drug Therapy, Computer-Assisted D006801:Humans D019934:International Normalized Ratio D055118:Medication Adherence D010865:Pilot Projects D011237:Predictive Value of Tests D017216:Telemedicine D013927:Thrombosis D016896:Treatment Outcome
antiphospholipid syndrome APSOnCloud vitamin K antagonist INR warfarin