Fat Matters: Understanding the Role of Adipose Tissue in Health in HIV Infection.
More than one-third of adults in the USA are obese and obesity-related disease accounts for some of the leading causes of preventable death. Mid-life obesity may be a strong predictor of physical function impairment later in life regardless of body mass index (BMI) in older age, highlighting the benefits of obesity prevention on health throughout the lifespan. Adipose tissue disturbances including lipodystrophy and obesity are prevalent in the setting of treated and untreated HIV infection. This article will review current knowledge on fat disturbances in HIV-infected persons, including therapeutic options and future directions.
['Erlandson|Kristine M|KM|', 'Lake|Jordan E|JE|']
D017667:Adipocytes D000273:Adipose Tissue D019380:Anti-HIV Agents D023241:Antiretroviral Therapy, Highly Active D050218:Body Fat Distribution D015658:HIV Infections D006801:Humans D008060:Lipodystrophy D009765:Obesity D014481:United States
Adipose tissue HIV HIV infection Obesity BMI Lipodystrophy Review Antiretroviral therapy HIV/AIDS Inflammation Obesity and HIV