Neuropsychiatric manifestations of Parkinson's disease.
OBJECTIVE
This clinical update review focuses on the classification and description of common neuropsychiatric manifestations in Parkinson's disease (PD).


METHOD
We conducted a systematic search of the literature using Pubmed and selected the most recent and relevant papers for this review.


RESULTS
Neuropsychiatric manifestations in PD are are very frequent and may arise from an abnormal psychopathological response to the disease, neurobiological changes related to the disease itself, complications of treatments or a combination of all of these.


CONCLUSIONS
Neuropsychiatric symptoms may precede the motor clinical presentation of PD. Early recognition is essential.
['Molina Ruiz|Rosa M|RM|', 'Evans|Andrew H|AH|', 'Velakoulis|Dennis|D|', 'Looi|Jeffrey Cl|JC|']
D006801:Humans D001523:Mental Disorders D058027:Neuropsychiatry D010300:Parkinson Disease
neuropsychiatric manifestations Parkinson’s disease psychiatry