Resection of a juvenile nasoangiofibroma by Le Fort I osteotomy: Experience with 40 cases.
PURPOSE
The aim of this study was to determine the rate of success and complications of juvenile nasoangiofibroma resection by Le Fort I osteotomy.


MATERIAL AND METHODS
Data were obtained from the medical records of 40 patients with a diagnosis of juvenile nasoangiofibroma confirmed by anatomopathological examination. All tumors were resected by Le Fort I osteotomy between 1983 and 2010. The data obtained were gender, age, symptoms, sites of invasion, preoperative embolization, routes of surgical access, duration of surgery, complications, need for transfusion, relapses, and follow-up time.


RESULTS
All patients were male, ranging in age from 7 to 27 years. The most common symptom was nasal obstruction, and central nervous system (CNS) invasion was present in 27.5% of cases. Craniotomy was associated with Le Fort I osteotomy in only one case. The mean duration of surgery was 216 min. Complications occurred in 15% of cases, with intraoperative bleeding being the most frequent one. Relapses occurred in 5% of cases. The mean follow-up was 48.8 months.


CONCLUSION
Exclusively surgical treatment by Le Fort I access proved to be a safe and effective method for the treatment of nasoangiofibromas, permitting the removal of tumors even in patients with extension to the CNS, with a low rate of complications and relapses.
['de Mello-Filho|Francisco Veríssimo|FV|', 'Araujo|Fernando Cesar França|FC|', 'Marques Netto|Paulo Barrero|PB|', 'Pereira-Filho|Francisco Januário Farias|FJ|', 'de Toledo-Filho|Rodolfo Cardoso|RC|', 'Faria|Ana Célia|AC|']
D000293:Adolescent D000328:Adult D018322:Angiofibroma D016063:Blood Loss, Surgical D001803:Blood Transfusion D016543:Central Nervous System Neoplasms D002648:Child D004621:Embolization, Therapeutic D005500:Follow-Up Studies D006801:Humans D007431:Intraoperative Complications D008297:Male D008437:Maxilla D015508:Nasal Obstruction D009361:Neoplasm Invasiveness D009364:Neoplasm Recurrence, Local D009367:Neoplasm Staging D009669:Nose Neoplasms D061646:Operative Time D019340:Osteotomy, Le Fort D011300:Preoperative Care D012189:Retrospective Studies D016896:Treatment Outcome D055815:Young Adult
Le Fort I osteotomy Surgery Juvenile nasopharyngeal angiofibroma