Esophageal Carcinosarcoma that Was Diagnosed as a Granulocyte-colony Stimulating Factor and Interleukin-6-producing Tumor with a Tumor Fever.
A 51-year-old man visited our hospital with a main complaint of precordial pain, difficulty swallowing, and pyrexia. The patient was diagnosed with esophageal carcinosarcoma, based on the characteristic morphology noted on upper gastrointestinal endoscopy and histology tests, and he underwent surgical treatment. His preoperative blood granulocyte-colony stimulating factor (G-CSF) and interleukin-6 (IL-6) levels were high, and the surgical specimens were positive in both immunohistochemical tests; therefore, he was diagnosed with a G-CSF- and IL-6-producing tumor. When pyrexia is seen as a paraneoplastic symptom, it is important to consider and investigate the possibility of a cytokine-producing tumor.
['Shioga|Taro|T|', 'Matsushima|Shozo|S|', 'Yamada|Eiji|E|', 'Uchiyama|Takashi|T|', 'Noto|Haruka|H|', 'Suzuki|Daisuke|D|', 'Nonaka|Takashi|T|', 'Miyazawa|Shiro|S|', 'Komatsu|Tatsuji|T|', 'Yamamoto|Yuji|Y|', 'Sekido|Hitoshi|H|', 'Niino|Hitoshi|H|']
D002296:Carcinosarcoma D003680:Deglutition Disorders D016145:Endoscopy, Digestive System D004938:Esophageal Neoplasms D005334:Fever D016179:Granulocyte Colony-Stimulating Factor D006801:Humans D007150:Immunohistochemistry D015850:Interleukin-6 D008297:Male D008875:Middle Aged
esophageal carcinosarcoma granulocyte-colony stimulating factor tumor fever interleukin-6