Does clinical presentation predict response to a nonsurgical chronic disease management program for endstage hip and knee osteoarthritis?
OBJECTIVE
To identify baseline characteristics of participants who will respond favorably following 6 months of participation in a chronic disease management program for hip and knee osteoarthritis (OA).


METHODS
This prospective cohort study assessed 559 participants at baseline and following 6 months of participation in the Osteoarthritis Chronic Care Program. Response was defined as the minimal clinically important difference of an 18% and 9-point absolute improvement in the Western Ontario and McMaster Universities Arthritis Index global score. Multivariate logistic regression modeling was used to identify predictors of response.


RESULTS
Complete data were available for 308 participants. Those who withdrew within the study period were imputed as nonresponders. Three variables were independently associated with response: signal joint (knee vs hip), sex, and high level of comorbidity. Index joint and sex were significant in the multivariate model, but the model was not a sensitive predictor of response.


CONCLUSION
Strong predictors of response to a chronic disease management program for hip and knee OA were not identified. The significant predictors that were found should be considered in future studies.
['Eyles|Jillian P|JP|', 'Lucas|Barbara R|BR|', 'Patterson|Jillian A|JA|', 'Williams|Matthew J|MJ|', 'Weeks|Kate|K|', 'Fransen|Marlene|M|', 'Hunter|David J|DJ|']
D000368:Aged D000704:Analysis of Variance D002908:Chronic Disease D015331:Cohort Studies D004185:Disability Evaluation D005260:Female D005500:Follow-Up Studies D006801:Humans D016015:Logistic Models D008297:Male D008875:Middle Aged D009517:New South Wales D015207:Osteoarthritis, Hip D020370:Osteoarthritis, Knee D010146:Pain D010147:Pain Measurement D026741:Physical Therapy Modalities D011237:Predictive Value of Tests D011446:Prospective Studies D016059:Range of Motion, Articular D012720:Severity of Illness Index D013997:Time Factors D016896:Treatment Outcome
CHRONIC DISEASE OSTEOARTHRITIS PREDICTOR MULTIDISCIPLINARY REGRESSION ANALYSIS REHABILITATION