Occurrence of common plastic additives and contaminants in mussel samples: Validation of analytical method based on matrix solid-phase dispersion.
A new matrix solid-phase dispersion (MSPD) extraction methodology, combined with high-performance liquid chromatography equipped with a diode-array detector, was developed and validated for the simultaneous determination of 10 compounds in mussels from Galician Rias (Spain). These pollutants are compounds commonly used for plastic production as additives, as well as common plastic contaminants. The compounds selected were bisphenol-A, bisphenol-F, bisphenol-S, nonylphenol-9, nonylphenol, diethyl phthalate, dibutyl phthalate, di-2-ethylhexyl phthalate, dichlorodiphenyltrichloroethane, dichlorodiphenyldichloroethane, and dichlorodiphenyldichloroethylene. The parameters affecting the MSPD extraction efficiency such as the type of sorbent, mass sample-sorbent ratio, and extraction solvent were optimised. The proposed method provided satisfactory quantitative recoveries (80-100%), with relative standard deviations lower than 7%. In all cases, the matrix-matched calibration curves were linear in the concentration range of 0.32-120.00 µg/kg, with quantification limits of 0.25-16.20 µg/kg. The novel developed MSPD-high-performance liquid chromatography methodology provided good sensitivity, accuracy, and repeatability for quality control analysis in mussels.
['Cañadas|R|R|', 'Garrido Gamarro|E|E|', 'Garcinuño Martínez|R M|RM|', 'Paniagua González|G|G|', 'Fernández Hernando|P|P|']
D000818:Animals D049872:Bivalvia D002851:Chromatography, High Pressure Liquid D052244:Endocrine Disruptors D057230:Limit of Detection D010969:Plastics D052616:Solid Phase Extraction D013030:Spain D014874:Water Pollutants, Chemical
Plastic additives Mussel samples Matrix solid-phase dispersion High-performance liquid chromatography Phthalates Alkylphenols Bisphenols