Autism, Psychosis, or Both? Unraveling Complex Patient Presentations.
Autism spectrum disorders (ASDs) and schizophrenia spectrum disorders co-occur at elevated rates. Although these conditions are diagnostically distinct, they share multiple clinical features and genetic risk factors. This article describes the epidemiologic features and clinical manifestations of psychosis in individuals with ASDs, while also discussing shared genetic risk factors and affected brain regions. Components of a diagnostic assessment, including a thorough developmental, behavioral, medical, and psychiatric history, will be reviewed. The authors highlight the manifestations of catatonia in this population and note the shared features between catatonia and ASDs. Finally, treatment approaches and areas for future study are suggested.
['Chandrasekhar|Tara|T|', 'Copeland|John Nathan|JN|', 'Spanos|Marina|M|', 'Sikich|Linmarie|L|']
D000067877:Autism Spectrum Disorder D002648:Child D006801:Humans D011618:Psychotic Disorders D012559:Schizophrenia
Psychosis Autism spectrum disorders Schizophrenia spectrum disorders 22q11.2 deletion syndrome