Cowden syndrome--a case report emphasizing the role of the dental surgeon in diagnosis.
Cowden syndrome or multiple hamartoma syndrome, is a rare genetic condition inherited in an autosomal dominant pattern characterized by cutaneous manifestations, polyps, thyroid gland neoplasias, and macrocephaly. This report presents the case of a 36-year-old patient who looked for dental treatment for a gingival nodule. Current and past medical history and oral and facial manifestations led to the diagnosis of Cowden syndrome. This case report emphasizes the role of the dental surgeon in the diagnosis of this systemic disease, based on the analysis of medical history and manifestations in the oral cavity.
['Webber|Liana Preto|LP|', 'Martins|Manoela Domingues|MD|', 'Carrard|Vinícius Coelho|VC|', 'Trevizani Martins|Marco Antônio|MA|', 'Munerato|Maria Cristina|MC|']
D000328:Adult D001706:Biopsy D001938:Brazil D003937:Diagnosis, Differential D003945:Diagnosis, Oral D005260:Female D006223:Hamartoma Syndrome, Multiple D006801:Humans
genetics Cowden disease PTEN hamartoma tumor syndrome oral papules trichilemmomas