Promoting resilience through neurocognitive functioning in youth living with HIV.
Using a phased model of intervention development, we developed an intervention to promote resilience in youth living with HIV via improved neurocognitive resources. First, youth completed a naturalistic prospective memory (PM) task and were randomized into a visualization condition or control condition. Next, 47 of these participants completed another naturalistic PM task and were randomized into Calendaring condition, an Alarm condition, a Combined condition, or a Control condition. Youth with low PM demonstrated observable gains from the visualization technique. Youth in the Combined Calendaring and Alarm condition demonstrated significantly better performance than participants in the Control and Calendaring conditions. In a Proof-of-Concept study with 16 youth, the previous findings were translated into a single session in-person intervention followed by tailored text messaging to improve adherence and viral load via improved neurocognitive resources. The resulting intervention showed a signal of effect with viral load reductions in youth with available data. Targeting compensatory strategies to enhance neurocognitive functioning may promote resilience and health outcomes. A randomized pilot study with a control condition is the next step.
['Pennar|Amy|A|', 'Naar|Sylvie|S|', 'Woods|Steven|S|', 'Nichols|Sharon|S|', 'Outlaw|Angulique|A|', 'Ellis|Deborah|D|']
D000293:Adolescent D003376:Counseling D005260:Female D015658:HIV Infections D006801:Humans D008297:Male D055118:Medication Adherence D008569:Memory Disorders D061212:Memory, Episodic D000066530:Neurological Rehabilitation D009483:Neuropsychological Tests D010865:Pilot Projects D011569:Psychiatric Status Rating Scales D055500:Resilience, Psychological D060145:Text Messaging D016896:Treatment Outcome D019562:Viral Load D055815:Young Adult
memory text messaging viral load Neuropsychological adolescent medication adherence self-management