Predictors of adequate intraprocedural premature ventricular complex (PVC) frequency during idiopathic PVC ablation.
BACKGROUND
The aim of the present study was to determine the predictors of adequate intraprocedural premature ventricular complex (PVC) frequency for successful mapping and ablation of idiopathic PVCs.


METHODS
A total of 101 consecutive patients (45 men; age: 47.9 ± 14.2 years) who had undergone idiopathic PVC ablation between 01 November 2018 and 24 June 2020 constituted our study population. Clinical and demographic data, procedural details and 24 h rhythm recordings that had been recorded before the procedure were retrospectively evaluated. Total PVC burden and diurnal variability assessed by the ratio of night time (22:00-06:00) over day time (06:00-22:00) PVC burden was calculated. The relationship between hourly PVC number and heart rate was also evaluated for each patient. Clinical characteristics and Holter parameters were compared between groups with and without adequate intraprocedural frequency of PVCs that permitted activation mapping.


RESULTS
In all, 27 patients (26.7%) had infrequent intraprocedural PVCs which necessitated isoproterenol infusion or cancellation of ablation procedure due to inability of activation mapping. PVC burden was significantly higher in the group with frequent intraprocedural PVCs (26.1 ± 9.4% vs 21.2 ± 10.3%; p: 0.026). There were no significant differences between groups regarding the relationship between hourly PVC number and heart rate or the ratio of night/day PVC burden. Binary logistic regression analysis revealed the 24 h Holter PVC burden as the sole parameter that is significant predictor of frequent intraprocedural PVCs permitting activation mapping.


CONCLUSION
The 24 h PVC burden was the only predictor of adequate intraprocedural PVC frequency permitting activation mapping during idiopathic PVC ablation.
['Demir|Serdar|S|', 'Gulsen|Kamil|K|', 'Kepez|Alper|A|http://orcid.org/0000-0003-3868-3268', 'Uslu|Abdulkadir|A|', 'Kup|Ayhan|A|', 'Kanar|Batur Gonenc|BG|', 'Kayan|Fethullah|F|', 'Yildirim|Cagan|C|', 'Akgun|Taylan|T|']
D000328:Adult D017115:Catheter Ablation D006339:Heart Rate D006801:Humans D008297:Male D008875:Middle Aged D012189:Retrospective Studies D018879:Ventricular Premature Complexes
Activation mapping Arrhythmias, cardiac Diurnal variability of premature ventricular complexes Heart diseases Radiofrequency ablation