Synthesis of NH-Sulfoximines by Using Recyclable Hypervalent Iodine(III) Reagents under Aqueous Micellar Conditions.
The synthesis of NH-sulfoximines from sulfides has been first developed under mild conditions in an aqueous solution with surfactant TPGS-750-M as the catalyst at room temperature. In this newly developed process, a simple and convenient recycling strategy to regenerate the indispensable hypervalent iodine(III) is used. The resulting 1,2,3-trifluoro-5-iodobezene can be recovered almost quantitively from the mixture by liquid-liquid extraction and then oxidized to give the corresponding iodine(III) species. This optimized procedure is compatible with a broad range of functional groups and can be easily performed on a gram scale, providing a green protocol for the synthesis of sulfoximines.
['Zhang|Guocai|G|', 'Tan|Hongsheng|H|', 'Chen|Weichun|W|', 'Shen|Hong C|HC|', 'Lu|Yue|Y|', 'Zheng|Changwu|C|http://orcid.org/0000-0002-0869-8314', 'Xu|Hongxi|H|']
recycling surfactants oxidation sulfoximines green chemistry