Oncologic and functional outcome of the preserved eye in malignant sinonasal tumors.
BACKGROUND
The purpose of this study was to analyze the oncologic and functional outcomes of the preserved eye in malignant sinonasal tumors with orbital involvement.


METHODS
In a retrospective study of 19 consecutive patients who underwent craniofacial resection or maxillectomy with preservation of orbital contents and adjuvant radiotherapy, the oncological outcome in terms of local recurrence and survival was analyzed. The functional outcome in the preserved eye was analyzed for the cases that did not recur in the orbit.


RESULTS
Nineteen patients were analyzed for their oncologic and functional outcomes. Fifteen patients underwent immediate reconstruction of the orbital support. Eight patients had local recurrences; 11 patients were disease free at the end of the follow-up. Squamous cell carcinoma has a high propensity for local recurrences (ie, 5 of 8 local recurrences were squamous cell carcinoma). Sixteen patients, in whom a satisfactory orbital tumor clearance was obtained, remained recurrence free in the orbit. All the preserved eyes retained adequate function after adjuvant radiotherapy.


CONCLUSIONS
Adequate local control with preserved visual function can be obtained with surgery and adjuvant radiation in appropriately selected malignant sinonasal tumors with orbital involvement. The preserved eye, if reconstructed appropriately, maintains good overall function with acceptable morbidity.
['Rajapurkar|Mayuri|M|', 'Thankappan|Krishnakumar|K|', 'Sampathirao|Leela Mohan C S|LM|', 'Kuriakose|Moni Abraham|MA|', 'Iyer|Subramania|S|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D001707:Biopsy, Needle D002294:Carcinoma, Squamous Cell D015331:Cohort Studies D018572:Disease-Free Survival D005123:Eye D005260:Female D005500:Follow-Up Studies D006801:Humans D007150:Immunohistochemistry D008297:Male D008437:Maxilla D008875:Middle Aged D009361:Neoplasm Invasiveness D009364:Neoplasm Recurrence, Local D009367:Neoplasm Staging D009918:Orbital Neoplasms D009926:Organ Preservation D010255:Paranasal Sinus Neoplasms D019651:Reconstructive Surgical Procedures D012189:Retrospective Studies D018570:Risk Assessment D016019:Survival Analysis
functional outcome preserved eye maxillectomy reconstruction head and neck cancer sinonasal cancer