Breaking the mold: structures of the RNA polymerase I transcription complex reveal a new path for initiation.
While structures of the RNA polymerase (Pol) II initiation complex have been resolved and extensively studied, the Pol I initiation complex remained elusive. Here, we review the recent structural analyses of the yeast Pol I transcription initiation complex that reveal several unique and unexpected Pol I-specific properties.
['Jackobel|Ashleigh J|AJ|', 'Han|Yan|Y|0000-0002-1207-7756', 'He|Yuan|Y|0000-0002-1455-3963', 'Knutson|Bruce A|BA|']
D012318:RNA Polymerase I D012441:Saccharomyces cerevisiae D061785:Transcription Initiation, Genetic
RNA polymerase I transcription initiation Core Factor pre-initiation complex promoter opening promoter recognition