Organic chromium modifies the expression of orexin and glucose transporters of ovarian in heat-stressed laying hens.
In this study, the effect of the supplemental organic chromium (Cr) forms on the expression of ovarian orexin(hypocretin), glucose transporters (GLUTs), heat shock proteins (HSPs) andnuclear factor-kappaB (NF-κB)were investigated in laying hens (HS). Laying hens (n=1800; 16-wk-old; Lohmann LSL-Lite) were allocated to 6 random groups according to a 2 × 3 factorial trial scheme with two different environmental temperatures [Thermoneutral (TN groups; at either 22±2 °C 24 h/d)  and heat stress (HS groups; at 34±2 °C for 8 h/d, 08:00 to 17:00 h, followed by 22°C for 16 h for a period of 12 wks)], andhens reared under both environmental conditions were fed either a basal diet or the basal diet supplemented with 1.600 mg of chromium-picolinate (CrPic, 12.43% Cr) and 0.788 mg of chromium-histidinate (CrHis, 25.22% Cr) per kg of diet, delivering 200 µg elemental Cr per kg diet. HS groups showed decreased levels of orexin and GLUTs(GLUT1, GLUT4), and increased NFκB, HSP60, HSP70 and HSP90 levels compared to the TN groups in ovarian tissue of hens (P &lt; 0.0001 for all).However, dietary chromium supplementation (CrPic-CrHis) increasedorexin and GLUTs levels and significantly reduced the NF-κB and HSPs levels making them closer to those of thermoneutral group (P &lt; 0.0001).In conclusion, CrPic and CrHis showed supported the relief and treatment of stress complications.
['Ozdemir|O|O|', 'Tuzcu|M|M|', 'Sahin|N|N|', 'Orhan|C|C|', 'Tuzcu|Z|Z|', 'Sahin|K|K|']
D000818:Animals D002645:Chickens D019587:Dietary Supplements D005260:Female D051246:Glucose Transport Proteins, Facilitative D006360:Heat-Shock Proteins D006639:Histidine D016328:NF-kappa B D000068797:Orexins D009942:Organometallic Compounds D010053:Ovary D010848:Picolinic Acids D013312:Stress, Physiological D013696:Temperature D015854:Up-Regulation
Chromium Orexin GLUTs Heat stress NFκB. Ovary