Association between breastfeeding and sleep patterns in infants and preschool children.
BACKGROUND
Although most studies have reported unfavorable short-term effects of breastfeeding on early-childhood sleep-wake behaviors that potentially attenuate over time, findings have remained inconsistent.


OBJECTIVES
We assessed associations of breastfeeding with longitudinal day-, night-, and total-sleep trajectories and with sleep-wake behaviors in healthy infants and preschoolers.


METHODS
Caregivers of naturally conceived, term, singleton infants (n = 654) completed the Brief Infant Sleep Questionnaire (3, 6, 9, 12, 18, and 24 mo) and/or Children's Sleep Habits Questionnaire (54 mo), and provided information on their infants' breastfeeding status at 3 mo. Trajectory analyses derived 4 day- (n = 243), 3 night- (n = 248), and/or 4 total- (n = 241) sleep trajectories, each differing in length of sleep duration (short/moderate/long) and variability (variable/consistent). Sleep-wake behaviors from 3 to 24 mo (day/night/total-sleep durations and duration/number of night awakenings) were also assessed for associations with breastfeeding.


RESULTS
After adjusting for potential covariates, formula-fed infants, relative to fully breastfed (predominant or exclusive) infants, were significantly less likely to exhibit moderate (OR: 0.28; 95% CI: 0.11, 0.70) and long consistent (OR: 0.18; 95% CI: 0.07, 0.50) night-sleep trajectories and less likely to exhibit moderate (OR: 0.21; 95% CI: 0.07, 0.61) and long consistent (OR: 0.12; 95% CI: 0.04, 0.38) and long variable (OR: 0.16; 95% CI: 0.05, 0.56) total-sleep trajectories, instead of short variable night- and total-sleep trajectories. Partially breastfed infants did not differ from fully breastfed infants for both night- and total-sleep trajectories. No significant differences were found between all groups for day-sleep trajectories. Fully breastfed infants had longer night- (6, 9, 12, and 24 mo) and total- (3 and 12 mo) sleep durations than formula-fed infants, albeit a greater number of night awakenings (from 6 to 12 mo).


CONCLUSIONS
Despite more night awakenings, fully breastfed infants have overall longer night- and total-sleep durations (sleep trajectories) than formula-fed infants.
['Abdul Jafar|Nur K|NK|', 'Tham|Elaine K H|EKH|', 'Pang|Wei W|WW|', 'Fok|Doris|D|', 'Chua|Mei C|MC|', 'Teoh|Oon-Hoe|OH|', 'Goh|Daniel Y T|DYT|', 'Shek|Lynette P-C|LP|', 'Yap|Fabian|F|', 'Tan|Kok H|KH|', 'Gluckman|Peter D|PD|', 'Chong|Yap-Seng|YS|0000-0002-7232-8473', 'Meaney|Michael J|MJ|', 'Broekman|Birit F P|BFP|', 'Cai|Shirong|S|']
breastfeeding infants preschoolers sleep trajectory sleep duration night awakenings development