Dietary citrus and/or its extracts intake contributed to weight control: Evidence from a systematic review and meta-analysis of 13 randomized clinical trials.
Randomized controlled trials, being published in English and investigating the associations of at least 4 weeks intervention of citrus and/or its extracts on weight loss among adults, were searched from PubMed, Web of Science, Scopus, and Cochrane by June 2019 to conduct a meta-analysis. Thirteen articles, including 921 participants, were selected and evaluated by modified Jadad scale. Pooled results by the random-effects model showed that citrus and/or its extracts administration significantly reduced 1.280 kg body weight (95% CI: -1.818 to -0.741, p = 0.000, I2 = 81.4%), 0.322 kg/m2 BMI (95% CI: -0.599 to -0.046, p = 0.022, I2 = 87.0%), 2.185 cm WC (95% CI: -3.804 to -0.566, p = 0.008, I2 = 98.3%), and 2.137 cm HC (95% CI: -3.775 to -0.500, p = 0.011, I2 = 96.2%), respectively, but no significantly decreased effects on WHR and body fat were observed. Subgroup analysis deduced the different effects of study location, intervention duration on body weight associated indices. No publication bias was observed. Our meta-analysis supported the beneficial effects of citrus and/or its extracts supplement on body weight control, and future well-designed studies are required to firmly establish the clinical efficacy of citrus and/or its extracts intervention on body weight.
['Wang|Xinjing|X|', 'Li|Deming|D|', 'Liu|Fang|F|', 'Cui|Yuan|Y|', 'Li|Xinli|X|https://orcid.org/0000-0002-3535-4787']
D000328:Adult D000368:Aged D001835:Body Weight D002957:Citrus D004032:Diet D005260:Female D005638:Fruit D006801:Humans D008297:Male D008875:Middle Aged D010936:Plant Extracts D016032:Randomized Controlled Trials as Topic D015431:Weight Loss D055815:Young Adult
citrus meta-analysis randomized clinical trial body weight citrus extracts