Radiotherapy supports tumor-specific immunity by acute inflammation.
Local immune stimulation is an integral part of radiotherapy. Production of anaphylatoxins is a crucial initial event in radiotherapy-induced immunity and clinical efficacy. We propose applying radiotherapy in few fractions and include radiation holidays to achieve acute rather than chronic inflammatory responses, which promote protective immunity and therapeutic efficacy.
['Surace|Laura|L|', 'Scheifinger|Nicole Angelika|NA|', 'Gupta|Anurag|A|', 'van den Broek|Maries|M|']
radiotherapy inflammation cancer immune response