Arterial spin-labeling MR imaging of cerebral hemorrhages.
INTRODUCTION
The purpose of this study is to identify the characteristics of brain perfusion measured by arterial spin-labeling magnetic resonance imaging (ASL-MRI) in cerebral hemorrhages.


METHODS
Brain blood flow values (CBF-ASL values) for cerebral and cerebellar hemispheres and segmented cerebral regions were measured by ASL-MRI in 19 putaminal hemorrhage patients and 20 thalamic hemorrhage patients in acute or subacute stages. We assessed the lateralities of CBF-ASL values and the relationships between CBF-ASL values and other imaging findings and clinical manifestations.


RESULTS
Both the 19 putaminal hemorrhage patients and the 20 thalamic hemorrhage patients had significantly low CBF-ASL values of the contralateral cerebellum in subacute stage, suggesting that ASL-MRI might delineate crossed cerebellar diaschisis (CCD). Ipsilateral low CBF-ASL values were observed in frontal lobes and thalami with a putaminal hemorrhage and lentiform nuclei, temporal lobes, and parietal lobes with a thalamic hemorrhage, suggesting that ASL-MRI showed the ipsilateral cerebral diaschisis (ICD). In the putaminal hemorrhage patients, the hematoma volume negatively affected both the bilateral cerebellar and cerebral hemispheric CBF-ASL values. In the thalamic hemorrhage patients, a concomitant intraventricular hemorrhage caused low cerebral hemispheric CBF-ASL values.


CONCLUSION
The use of ASL-MRI is sensitive to the perfusion abnormalities and could thus be helpful to estimate functional abnormalities in cerebral hemorrhage patients.
['Noguchi|Tomoyuki|T|', 'Nishihara|Masashi|M|', 'Egashira|Yoshiaki|Y|', 'Azama|Shinya|S|', 'Hirai|Tetsuyoshi|T|', 'Kitano|Isao|I|', 'Yakushiji|Yusuke|Y|', 'Kawashima|Masatou|M|', 'Irie|Hiroyuki|H|']
D000368:Aged D001783:Blood Flow Velocity D001810:Blood Volume D001921:Brain D002536:Cerebral Arteries D002543:Cerebral Hemorrhage D002560:Cerebrovascular Circulation D005260:Female D006801:Humans D007089:Image Enhancement D007090:Image Interpretation, Computer-Assisted D018810:Magnetic Resonance Angiography D008297:Male D008875:Middle Aged D015203:Reproducibility of Results D012680:Sensitivity and Specificity D013113:Spin Labels
Arterial spin-labeling Cerebral hemorrhage Brain perfusion Putaminal hemorrhage Thalamic hemorrhage