Desirability, availability, credit assignment, category learning, and attention: Cognitive-emotional and working memory dynamics of orbitofrontal, ventrolateral, and dorsolateral prefrontal cortices.
Background
The prefrontal cortices play an essential role in cognitive-emotional and working memory processes through interactions with multiple brain regions.


Methods
This article further develops a unified neural architecture that explains many recent and classical data about prefrontal function and makes testable predictions.


Results
Prefrontal properties of desirability, availability, credit assignment, category learning, and feature-based attention are explained. These properties arise through interactions of orbitofrontal, ventrolateral prefrontal, and dorsolateral prefrontal cortices with the inferotemporal cortex, perirhinal cortex, parahippocampal cortices; ventral bank of the principal sulcus, ventral prearcuate gyrus, frontal eye fields, hippocampus, amygdala, basal ganglia, hypothalamus, and visual cortical areas V1, V2, V3A, V4, middle temporal cortex, medial superior temporal area, lateral intraparietal cortex, and posterior parietal cortex. Model explanations also include how the value of visual objects and events is computed, which objects and events cause desired consequences and which may be ignored as predictively irrelevant, and how to plan and act to realise these consequences, including how to selectively filter expected versus unexpected events, leading to movements towards, and conscious perception of, expected events. Modelled processes include reinforcement learning and incentive motivational learning; object and spatial working memory dynamics; and category learning, including the learning of object categories, value categories, object-value categories, and sequence categories, or list chunks.


Conclusion
This article hereby proposes a unified neural theory of prefrontal cortex and its functions.
['Grossberg|Stephen|S|']
Category learning working memory inferotemporal cortex perirhinal cortex ventral bank of the principal sulcus ventral prearcuate gyrus frontal eye fields amygdala basal ganglia reinforcement learning incentive motivational learning cognitive-emotional interactions contextual cueing dorsolateral prefrontal cortex orbitofrontal cortex parahippocampal cortex ventrolateral prefrontal cortex