Vascular risk in migraineurs: interaction of endothelial and cortical excitability factors.
BACKGROUND
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.


RESULTS
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.


CONCLUSION
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.
['Murinova|Natalia|N|', 'Krashin|Daniel L|DL|', 'Lucas|Sylvia|S|']
D002561:Cerebrovascular Disorders D013181:Cortical Spreading Depression D006801:Humans D008881:Migraine Disorders D012307:Risk Factors
migraine stroke endothelial dysfunction coronary artery disease hypercoagulable state