Electrophysiological correlates of disobedience and feigning-like behaviour in motor imagery.
OBJECTIVE
To explore motor excitability changes induced by disobedience and feigning-like behaviour.


METHODS
Healthy subjects participated in motor imagery tasks. They imagined either a maximum muscle relaxation (condition 1) or a pinch grip (condition 2). In other trials, they were instructed to disobey the command to imagine a pinch grip. Instead, they should either imagine a maximum muscle relaxation (condition 3) or think of something else which they could choose freely (condition 4). Transcranial magnetic stimulation was used to explore motor excitability during the different tasks. Motor evoked potential amplitudes were expressed as percentage of the task-free control condition (condition 5).


RESULTS
Imagination of a pinch grip enhanced motor excitability, imagery of maximum muscle relaxation reduced motor excitability below the level of the control condition. In conditions 3 and 4, motor excitability was lower than in condition 2. However, motor excitability in condition 3 was higher than in condition 1.


CONCLUSIONS
Healthy subjects successfully disobeyed the motor imagery command but failed to maintain the down-regulation of motor excitability when trying to imagine maximum muscle relaxation.


SIGNIFICANCE
The results help to interpret the down-regulation of motor excitability found in patients with motor conversion disorder.
['Liepert|Joachim|J|', 'Shala|Januz|J|', 'Greiner|Johanna|J|']
D000328:Adult D004576:Electromyography D019054:Evoked Potentials, Motor D005260:Female D018737:Hand Strength D006801:Humans D007092:Imagination D008297:Male D008875:Middle Aged D009068:Movement D009126:Muscle Relaxation D018482:Muscle, Skeletal D011712:Pyramidal Tracts D050781:Transcranial Magnetic Stimulation
Disobedience Feigning-like behaviour Motor imagery Transcranial magnetic stimulation