Blood transfusion and lung surgeries in pediatric age group: A single center retrospective study.
Background
Blood transfusion is not without harm, and recent studies suggest association between transfusion and poor outcome in critically ill patients. Although it is prescribed for many reasons based on the firm belief that blood transfusion improves oxygen carrying capacity, it carries notable adverse hazards. Importantly, lung surgeries are counted as moderate to high-risk operations and take a significant risk of blood loss.


Aim
This study aims to reveal the association between blood transfusion and poor clinical outcomes and characterize the epidemiology of blood transfusion after pediatric chest surgery.


Settings and Design
Retrospective cohort study, done throughout 3 years.


Materials and Methods
A total of 248 patients who underwent open thoracotomy and lung surgery and aged ≤18 years were classified according to the need of intraoperative or postoperative blood transfusion into two groups: Group I (non-transfused = 130) and Group II (transfused = 118).


Statistical Analysis
SPSS v25 was used for analysis.


Results
Transfusion probability ranged between 42.8% and 50% according to type of surgery. As regard to postoperative variables, there was no significant difference between both groups regarding the duration of analgesia, allergic reactions, need of re-operation and in-hospital mortality. However, transfused group showed significant increase in duration of antibiotic, persistent postoperative fever, time to remove chest drains, ICU stays, hospital stay and pneumonia. Incidence of pneumonia had a relative risk 1.82 with transfused compared to non-transfused group.


Conclusion
Transfusion group in pediatrics undergoing lung surgeries in our study was more prone to adverse outcomes such as pneumonia, delayed time to remove chest drains, prolonged ICU stay, and hospital stay.
['Elgebaly|Ahmed S|AS|', 'Fathy|Sameh M|SM|', 'Elmorad|Mona B|MB|', 'Sallam|Ayman A|AA|']
D001803:Blood Transfusion D002648:Child D015331:Cohort Studies D005260:Female D006801:Humans D007902:Length of Stay D008168:Lung D008297:Male D010372:Pediatrics D011014:Pneumonia D011183:Postoperative Complications D012189:Retrospective Studies
Blood transfusion lung surgeries pediatrics retrospective study