Postoperative survival According to the Glasgow Prognostic
Score in Patients with Resected Lung Adenocarcinoma
Background: The Glasgow Prognostic Score (GPS) is calculated from measured CRP and albumin levels. We here
evaluated the significance of the GPS in patients with resected pulmonary adenocarcinoma. Materials and Methods:
The present study included 156 patients with lung adenocarcinoma who underwent lobectomy at Kanazawa Medical
University between 2002 and 2012. Classification was into three groups: those with normal albumin (>=3.5 g/dl) and
C-reactive protein (CRP) (<=1.0 mg/dl) levels were classified as GPS 0 (n =136), those with low albumin (<3.5 g/
dl) or elevated CRP (>1.0 mg/dl) levels as GPS 1 (n = 16), and those with low albumin (<3.5 g/dl) and elevated CRP
(>1.0 mg/dl) levels as GPS 2 (n = 4). We retrospectively investigated relationships between the patient characteristics
including the GPS, and disease-free survival and cancer-specific survival. Results: The pathological stages of the
patients were as follows: IA (n=78, 50%), IB (n=31, 19.9%), IIA (n=20.0, 12.8%), IIB (n=9.0, 5.7%), and IIIA (n=18.0,
11.5%). Lobectomy was performed in all cases. The average GPS was 0.15 (0-2) and showed significant relationships
with stage and tumor size. The 2-year survival rates in patients with GPS0, 1 and 2 were 81.4%, 38.4%, and 25.0%,
respectively. Clear correlations were noted with both cancer-specific survival and disease-free survival. Furthermore,
multivariate analysis revealed that GPS was a significant prognostic factor. Conclusions: The GPS could be a prognostic
factor for patients with resected pulmonary adenocarcinoma.
['Machida|Yuichiro|Y|', 'Sagawa|Motoyasu|M|', 'Tanaka|Makoto|M|', 'Motono|Nozomu|N|', 'Matsui|Takuma|T|', 'Usuda|Katsuo|K|', 'Uramoto|Hidetaka|H|']
glasgow prognostic score Lung adenocarcinoma prognosis