Workup of Gastroenteropancreatic Neuroendocrine Tumors.
Neuroendocrine tumors of the gastrointestinal tract or pancreas are rare. Their presentation overlaps with other intra-abdominal neoplasms, but can have unique features. The workup involves recognition of unusual clinical features associated with the tumors, imaging, analysis of blood or urine concentrations, and biopsy. Functional imaging takes advantage of the neuroendocrine tumor-specific expression of somatostatin receptors. There are characteristic features supporting the diagnosis on contrast-enhanced cross-sectional imaging. The use of tumor markers for biochemical diagnosis requires an understanding of the confounding variables affecting these assays. There are unique and specific immunohistochemical staining and grading requirements for appropriate diagnosis of these tumors.
['Dillon|Joseph S|JS|']
D000818:Animals D014408:Biomarkers, Tumor D006801:Humans D007414:Intestinal Neoplasms D057054:Molecular Imaging D018358:Neuroendocrine Tumors D010190:Pancreatic Neoplasms D013274:Stomach Neoplasms
Gastroenteropancreatic neuroendocrine tumors Imaging Biopsy Tumor markers Clinical presentation