Preoperative diagnosis of a solid pseudopapillary tumour of the pancreas by Endoscopic Ultrasound Fine Needle Biopsy: A retrospective case series.
BACKGROUND
A solid pseudopapillary tumour of the pancreas (SPTP) is a rare neoplasm.


AIM
We herein present five cases of SPTP diagnosed using endoscopic ultrasound (EUS) guided fine-needle biopsy (FNB) using a needle with side fenestration (ProCore-needle).


METHODS
From January 2011 to June 2012 in five patients with SPTP tissue acquisition was carried out with a 19-gauge (4 patients) or a 22-gauge (one patient) needle.


RESULTS
The mean age of the patients was 30.8 years, the mean lesion size was 49mm and the most common location was the tail of the pancreas (3 cases). When the samples were evaluated macroscopically, small core fragments were observed in all cases. A preoperative diagnosis of SPTP was made in all patients on the basis of the histocytological and characteristic immunophenotypic patterns and was confirmed at final surgical histology.


CONCLUSIONS
In our experience, EUS-FNB is an effective and secure method for a preoperative diagnosis of SPTP.
['Maimone|Antonella|A|', 'Luigiano|Carmelo|C|', 'Baccarini|Paola|P|', 'Fornelli|Adele|A|', 'Cennamo|Vincenzo|V|', 'Polifemo|Annamaria|A|', 'Fiscaletti|Marta|M|', 'de Biase|Dario|D|', 'Jaboli|Francesca|F|', 'Virgilio|Clara|C|', 'Stelitano|Liliana|L|', 'Zanini|Nicola|N|', 'Masetti|Michele|M|', 'Jovine|Elio|E|', 'Fabbri|Carlo|C|']
D000293:Adolescent D000328:Adult D044963:Biopsy, Fine-Needle D002291:Carcinoma, Papillary D003937:Diagnosis, Differential D019160:Endosonography D005260:Female D005500:Follow-Up Studies D006801:Humans D061705:Image-Guided Biopsy D008297:Male D008875:Middle Aged D010179:Pancreas D010180:Pancreatectomy D010190:Pancreatic Neoplasms D057234:Preoperative Period D015203:Reproducibility of Results D012189:Retrospective Studies D055815:Young Adult
Solid pseudopapillary tumour Endoscopic ultrasound Fine-needle biopsy Pancreatic mass