Triterpenes and limonoids of Cedrela: Distribution, biosynthesis, and 1 H and 13 C NMR data.
Cedrela genus, a member of the Meliaceae family, presents both chemical characteristics associated with and those that distinguish it from the rest of its members. The presence of triterpenes and limonoids is the characteristic of the Meliaceae family, but the class and type of these chemical constituents are distinctive for each genus. Cedrela includes cycloartane, ursane, oleanane, tirucallane, butyrospermane, and apotirucallane triterpenes, and its limonoids belongs to six class and nine types, known as class Ia-type havanensines, class Ib-type delevoyin, class II-type gedunin, class IIIb-type andirobin, class IIIg-type mexicanolide, class IVa-type evoludone, class Va-type obacunol, class V-type limonin, and class VIII. Each of these structural arrangements includes specific traits, defined by their biosynthetic origin, which can be established by means of structural elucidation techniques, particularly 1 H and 13 C NMR, which assisted by 2D NMR techniques, allowing to deduce their structures unequivocally. The constant presence of these skeletal arrangements in Cedrela ensures that they are its chemophenetic markers and their recurrence is an important criterion for their identity. This review is a compilation of the occurrence of triterpenes and limonoids in Cedrela genus, detailing their biosynthetic association and collecting and organizing their NMR data, with the purpose of facilitating its location, analysis, and use in the phytochemical study of species from this genus.
['Vasquez-Ruiz|Vianey|V|https://orcid.org/0000-0002-8371-7431', 'Ramírez-Cisneros|M Ángeles|MÁ|https://orcid.org/0000-0003-4696-7359', 'Rios|Maria Yolanda|MY|https://orcid.org/0000-0002-8875-8734']
triterpenes limonoids Cedrela distribution biosynthesis NMR chemophenetic 13C 1H tetranortriterpenes