In vitro biocompatibility of titanium after plasma surface alloying with boron.
Recently, the effect of different sizes of precursor powders during surface plasma alloying modification on the properties of titanium surface was studied. In this work we show in vitro test results of the titanium (α-Ti) after plasma surface alloying with boron (B). Ti-B nanopowders with 2 and 10wt% B were deposited onto microcrystalline Ti substrate. The in vitro cytocompatibility of these biomaterials was evaluated and compared with a conventional microcrystalline Ti. During the studies, established cell line of human gingival fibroblasts and osteoblasts were cultured in the presence of tested materials, and its survival rate and proliferation activity were examined. For this purpose, MTT assay, flow cytometric and fluorescent microscopic evaluation were made. Biocompatibility tests carried out indicate that the Ti after plasma surface alloying with B could be a possible candidate for dental implants and other medicinal applications. Plasma alloying is a promising method for improving the properties of titanium, thus increasing the field of its applications.
['Kaczmarek|Mariusz|M|', 'Jurczyk|Mieczysława U|MU|', 'Miklaszewski|Andrzej|A|', 'Paszel-Jaworska|Anna|A|', 'Romaniuk|Aleksandra|A|', 'Lipińska|Natalia|N|', 'Żurawski|Jakub|J|', 'Urbaniak|Paulina|P|', 'Jurczyk|Karolina|K|']
D000497:Alloys D001672:Biocompatible Materials D001895:Boron D002453:Cell Cycle D016923:Cell Death D002470:Cell Survival D002478:Cells, Cultured D003460:Crystallization D005347:Fibroblasts D005453:Fluorescence D006801:Humans D008422:Materials Testing D010006:Osteoblasts D058626:Plasma Gases D013499:Surface Properties D014025:Titanium D014961:X-Ray Diffraction
Titanium Boron Cell proliferation Cell viability Microplasma alloying Nanoprecursors