Sensitive surface-enhanced Raman spectroscopy (SERS) determination of nitrofurazone by β-cyclodextrin-protected AuNPs/γ-Al2O3 nanoparticles.
A novel surface-enhanced Raman spectroscopy (SERS) method for the determination of nitrofurazone was developed using AuNPs/γ-Al2O3 nanoparticles protected by β-cyclodextrin (β-CD) as substrate prepared in our lab. The optimum experimental conditions were obtained from single factor procedure and response surface modeling. A linear relationship (ISERS = 508.96c + 31987.87, c: nmol L-1, R2 = 0.996) between SERS intensity and the concentration of nitrofurazone in the range of 3.3 - 667.0 nmol L-1 was established, the limit of detection (LOD) was found at nmol L-1 level (0.37 nmol L-1 by 3S0/S). The selectivity for the method was studied by the influences of foreign substances on the determination. The recoveries and RSD (n = 5) for the six meat samples were 95.1 % - 104.5% and 2.4 % - 4.8% respectively, which suggesting that the new SERS method was successfully to detecting nitrofurazone.
['Bi|Shuyun|S|', 'Shao|Di|D|', 'Yuan|Yue|Y|', 'Zhao|Rui|R|', 'Li|Xu|X|']
D006046:Gold D053768:Metal Nanoparticles D009583:Nitrofurazone D013059:Spectrum Analysis, Raman D047392:beta-Cyclodextrins
Surface-enhanced Raman spectroscopy (SERS) Nitrofurazone Chicken Duck β-CD/AuNPs/γ-Al(2)O(3) nanoparticles