The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies.
INTRODUCTION
Recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies and clinical trials limit the development of new treatments. Widespread Internet use allows data capture from participants in an unsupervised setting. The Brain Health Registry, a website and online registry, collects data from participants and their study partners.


METHODS
The Brain Health Registry obtains self and study partner report questionnaires and neuropsychological data, including the Cogstate Brief Battery, Lumos Labs Neurocognitive Performance Test, and MemTrax Memory Test. Participants provide informed consent before participation.


RESULTS
Baseline and longitudinal data were obtained from nearly 57,000 and 28,000 participants, respectively. Over 18,800 participants were referred to, and nearly 1800 were enrolled in, clinical Alzheimer's disease and aging studies, including five observational studies and seven intervention trials.


DISCUSSION
Online assessments of participants and study partners provide useful information at relatively low cost for neuroscience studies and clinical trials and may ultimately be used in routine clinical practice.
['Weiner|Michael W|MW|', 'Nosheny|Rachel|R|', 'Camacho|Monica|M|', 'Truran-Sacrey|Diana|D|', 'Mackin|R Scott|RS|', 'Flenniken|Derek|D|', 'Ulbricht|Aaron|A|', 'Insel|Philip|P|', 'Finley|Shannon|S|', 'Fockler|Juliet|J|', 'Veitch|Dallas|D|']
D000544:Alzheimer Disease D001921:Brain D002986:Clinical Trials as Topic D005260:Female D006801:Humans D020407:Internet D008137:Longitudinal Studies D008297:Male D008875:Middle Aged D009483:Neuropsychological Tests D018579:Patient Selection D012042:Registries D011795:Surveys and Questionnaires
Alzheimer's disease Clinical trial recruitment Internet registry Neuroscience clinical research studies Online neuropsychological tests