Reduction in body cell mass as a predictor of osteoporosis: A cross-sectional study.
Objectives: Improvement of nutritional status, which may help prevent osteoporosis, can be assessed using the body cell mass (BCM) index, measured by the bioelectrical impedance analysis (BIA). However, the relationship between BCM and osteoporosis is not clear. This cross-sectional study investigated the association between osteoporosis and four components of body composition, including BCM.Methods: The study included 600 participants who underwent measurements of bone status by quantitative ultrasound and body composition by BIA at an annual health check-up. Normal and osteoporosis groups were compared.Results: There were 414 and 186 participants in the normal and osteoporosis groups, respectively. Significant differences between the two groups were observed in age, sex, height, weight, BCM, extracellular water (ECW) content, and minerals, even after adjusting for age and sex. In logistic regression analysis, BCM, age, and ECW were significant risk factors for osteoporosis. Furthermore, BCM and ECW in males and BCM and age in females were significant risk factors for osteoporosis.Conclusion: Of the four body composition components measured with BIA, reduction in BCM most reflected osteoporosis. BCM was a significant risk factor in both sexes for osteoporosis. BCM can be easily measured, and may be useful in the prevention and treatment of osteoporosis.
['Tanaka|Satoshi|S|http://orcid.org/0000-0003-4606-1522', 'Ando|Kei|K|', 'Kobayashi|Kazuyoshi|K|', 'Seki|Taisuke|T|', 'Hamada|Takashi|T|', 'Machino|Masaaki|M|', 'Ota|Kyotaro|K|', 'Morozumi|Masayoshi|M|', 'Kanbara|Shunsuke|S|', 'Ito|Sadayuki|S|', 'Ishiguro|Naoki|N|', 'Hasegawa|Yukiharu|Y|', 'Imagama|Shiro|S|http://orcid.org/0000-0002-6951-8575']
D000328:Adult D001823:Body Composition D015992:Body Mass Index D001834:Body Water D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D010024:Osteoporosis D012307:Risk Factors D014463:Ultrasonography
body cell mass osteoporosis Bioelectrical impedance analysis body composition quantitative ultrasound