Critical limb ischemia update and the evolving role of drug-elution technologies.
Critical limb ischemia (CLI) is a prevalent condition associated with cardiovascular mortality and limb loss. Areas covered: This review discusses the epidemiology of CLI, revascularization options, and drug-elution therapies. Expert commentary: Drug-eluting stents (DES) and drug-coated balloons (DCB) improve patency rates in the femoropopliteal segment, and are generally used as first-line therapies. For below-knee disease, angioplasty is the default strategy unless lesions are focal whereby DES can be used to reduce restenosis risk.
['Hooker|Jared B|JB|', 'Hawkins|Beau M|BM|']
D000800:Angioplasty, Balloon D002317:Cardiovascular Agents D054855:Drug-Eluting Stents D006801:Humans D035002:Lower Extremity D017239:Paclitaxel D058729:Peripheral Arterial Disease D016896:Treatment Outcome
critical limb ischemia Peripheral artery disease drug coated balloon drug coated stent paclitaxel