Isoquinoline alkaloids from Asimina triloba.
A new aporphine glycoside, (-)-anolobine-9-O-β-D-glucopyranoside was isolated from the twigs of pawpaw (Asimina triloba) along with 7 known alkaloids including five aporphine alkaloids (anolobine, nornuciferine, norushinsunine, liriodenine, and lysicamine), a proaporhine alkaloid (stepharine), and a tetrahydrobenzylisoquinoline alkaloid (coclaurine). Among these compounds, nornuciferine, lysicamine, stepharine, and coclaurine are reported for the first time from this plant. The structure of the new compound was elucidated by spectroscopic methods, including 1 D, 2 D NMR, and HRESI-MS. The absolute configuration of compounds 1, 2, 7 and 8 was determined by CD experiment.
['Majrashi|Taghreed A|TA|', 'Zulfiqar|Fazila|F|', 'Chittiboyina|Amar G|AG|', 'Ali|Zulfiqar|Z|', 'Khan|Ikhlas A|IA|']
D000470:Alkaloids D001060:Aporphines D031042:Asimina D007546:Isoquinolines D009682:Magnetic Resonance Spectroscopy D015394:Molecular Structure D021241:Spectrometry, Mass, Electrospray Ionization
alkaloids aporphine NMR Annonaceae anolobine-9-O-β-D-glucopyranoside