In vivo exfoliating efficacy of biodegradable beads and the correlation with user's satisfaction.
BACKGROUND/PURPOSE
By the end of 2017, non-biodegradable microbeads will be prohibited in USA, UK and Europe, due to their environmental issue. There are biodegradable beads available, but their effect on skin desquamation has not been evaluated yet. This study aimed to understand the skin renewal time, moisturizing effect and user's satisfaction of gel scrubs containing different exfoliating beads.


METHODS
Gel scrubs, containing polyethylene, mannan or wax beads, were used in this study. The stratum corneum turnover time (SCTT) and skin hydration were evaluated by dansyl chloride staining technique and Corneometer® , respectively. The self-assessment was also performed after a 3-week home use trial.


RESULTS
The SCTTs of three different gel scrubs were not significantly different. A numerical increase in the skin hydration level was found in all groups. Satisfaction scores for the appearance and usability attributes were similar, but scores for improvement in the skin hydration and skin smoothness were higher in the gel scrubs with mannan or wax beads.


CONCLUSION
All three gel scrubs provided a similar effect on the SCTT and skin hydration, but gel scrubs with mannan or wax beads were more favorable. Thus, these two biodegradable exfoliating beads may be good substitutes in scrubbing products.
['Kitsongsermthon|J|J|http://orcid.org/0000-0002-1031-8253', 'Kreepoke|J|J|', 'Duangweang|K|K|', 'Tansirikongkol|A|A|http://orcid.org/0000-0001-7106-0228']
D000293:Adolescent D063566:Biodegradable Plastics D001834:Body Water D003258:Consumer Behavior D003619:Dansyl Compounds D003869:Dermabrasion D005260:Female D005782:Gels D006801:Humans D007641:Keratolytic Agents D008297:Male D008351:Mannans D008863:Microspheres D012867:Skin D014885:Waxes D055815:Young Adult
moisturizing effect gel scrubs exfoliating beads stratum corneum turnover time dansyl chloride Corneometer®