Cerium oxide nanoparticles: green synthesis and biological applications.
CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size, agglomeration status in liquid, and surface charge, play important roles in the ultimate interactions of the NP with target cells. Recently, CeO2-NPs have been synthesized through several bio-directed methods applying natural and organic matrices as stabilizing agents in order to prepare biocompatible CeO2-NPs, thereby solving the challenges regarding safety, and providing the appropriate situation for their effective use in biomedicine. This review discusses the different green strategies for CeO2-NPs synthesis, their advantages and challenges that are to be overcome. In addition, this review focuses on recent progress in the potential application of CeO2-NPs in biological and medical fields. Exploiting biocompatible CeO2-NPs may improve outcomes profoundly with the promise of effective neurodegenerative therapy and multiple applications in nanobiotechnology.
['Charbgoo|Fahimeh|F|', 'Ahmad|Mansor Bin|MB|', 'Darroudi|Majid|M|']
D001704:Biopolymers D015374:Biosensing Techniques D002563:Cerium D004798:Enzymes D055772:Green Chemistry Technology D053758:Nanoparticles
cerium oxide nanoparticles green synthesis size biocompatibility morphology surface Ce3+