Adjuvant hypofractionated partial-brain radiation therapy for pediatric Ewing sarcoma brain metastases: case report.
This case report demonstrates that hypofractionated partial-brain radiation therapy with limited margins is a reasonable approach following gross tumor resection of Ewing sarcoma metastases to the brain. The patient presented with 2 intracranial metastases treated with gross-total resection followed by radiation therapy to 30 Gy in 5 fractions. The patient experienced symptomatic treatment-related inflammatory changes with resolution after receiving dexamethasone. He remains alive at 21 months of follow-up with no evidence of disease.
['van Dams|Ritchell|R|', 'Park|Henry S|HS|', 'Alomari|Ahmed K|AK|', 'Ricciardi|Adele S|AS|', 'Rao|Harini|H|', 'McNamara|Joseph|J|', 'DiLuna|Michael L|ML|', 'Bindra|Ranjit S|RS|']
D001932:Brain Neoplasms D002648:Child D006801:Humans D008297:Male D000069473:Radiation Dose Hypofractionation D018714:Radiotherapy, Adjuvant D012512:Sarcoma, Ewing
radiation therapy Ewing sarcoma brain metastases GTR = gross-total resection WBRT = whole-brain radiation therapy oncology radiation necrosis