Swertia chirata: A Comprehensive Review with Recent Advances.
BACKGROUND
Swertia chirata, an ethnomedicinal plant, is renowned for its diverse medicinal properties. The plant produces large number of therapeutic phytochemicals responsible for remedial effect against various ailments mainly chronic fever, malaria, bronchial asthma, liver disorders, certain type of mental disorder, blood purification and diabetes. Recently reported anticancer effect of S. chirata has amplified its importance in the scientific community.


OBJECTIVE
The aim of this review is to deliver the pharmaceutical importance of S. chirata as diverse therapeutic agent and attract the scientific community working in the field of pharmacology to produce new drug to treat various ailments.


METHODOLOGY
Data compiled and presented here were obtained from E-resources like Science Direct, Pubmed, Google, through books and web of science up to Oct 2017.


RESULT
This review comprises the common aspects of S. chirata like pharmacologically important phytochemicals with in vitro and in vivo studies, toxicology, adulteration with similar species, dosage, conservation via in vitro studies and genetic stability with molecular markers. A bioinformatics approach to explore therapeutic targets that might suppress many diseases is also compiled to make it complete.


CONCLUSION
The medicinal plant S. chirata is continuously being used as a traditional herb. The data indicated its safe and positive effect in the treatment of various diseases. It presents many promising prospects for modern medicine, which may be validated after the process of successful in vivo research, clinical studies, and human trials.
['Jauhari|Nupur|N|', 'Bharadvaja|Navneeta|N|', 'Sharma|Neelam|N|']
D000818:Animals D006801:Humans D007194:India D008515:Medicine, Ayurvedic D008519:Medicine, Traditional D008517:Phytotherapy D010936:Plant Extracts D010946:Plants, Medicinal D029967:Swertia
Swertia chirata Bioinformatics hepatoprotective hypoglycemic modern drug traditional medicine