Chinese Cancer Research in 2009-18 and the Disease Burden.
Objective
We investigated the correlation of cancer research in China with its disease burden and national or provincial wealth. We also compared China's research output with that of other Asian countries.


Methods
Chinese publications on cancer research for 2009-18 were retrieved from the Web of Science with a special filter giving high precision and recall. Their volume relative to gross domestic product (GDP) was compared with those of 14 Asian countries, and provincial outputs with provincial GDPs. Their distribution by anatomical site was compared with China's disease burden, and by research type with that of Europe.


Results
Chinese cancer research publications (including those from Taiwan) have grown rapidly in the last 10 years, and overtook those of the USA in 2018. Relative to other Asian countries, Chinese output was approximately proportionate to its wealth. Relative to its cancer burden (as a percentage of the total disease burden), China published an appropriate amount of cancer research in 2009-13, but almost one-third more in 2014-18. Its distribution between the provinces reflected their wealth, but with comparatively greater outputs from Beijing and Shanghai. The distribution of China's cancer research portfolio by anatomical site corresponded to its disease burden quite well, with a heavy emphasis on liver and stomach cancer. However, China did relatively less research on screening, diagnosis, palliative care, or quality of life.


Conclusion
The national and provincial cancer research in China in the past 10 years correlated relatively well with its disease burden and economic level, but over-emphasised basic research compared with prevention, screening and end-of-life care.
['Li|Aihua|A|0000-0001-6742-3268', 'Lewison|Grant|G|0000-0002-4493-1216']
Chinese cancer research anatomical site research type burden of disease comparison with GDP