Do adjunctive interventions in patients undergoing rapid maxillary expansion increase the treatment effectiveness?
OBJECTIVES
To evaluate the clinical effectiveness of adjunctive interventions in individuals undergoing rapid maxillary expansion (RME).


MATERIALS AND METHODS
MEDLINE, Web of Science, Cochrane, Scopus, LILACS, and Google Scholar were searched without restrictions up to June 2020. Trials involving participants undergoing orthopedic or surgical RME, along with adjunctive interventions, were included. Risk-of-bias assessments were performed using the Cochrane tool for randomized trials-2. The certainty level of evidence was assessed through the Grading of Recommendations Assessment, Development and Evaluation tool.


RESULTS
Six randomized clinical trials, with low to high risk of bias, were included. Low certainty of the evidence suggested that low-level laser facilitated opening of the midpalatal suture during the active phase of RME. Likewise, moderate certainty demonstrated that low-level laser accelerated the healing process of the suture during the retention phase. The clinical impact of this outcome, that is, stability and retention time, was not evaluated. Very low evidence indicated that osteoperforations along the midpalatal suture increased maxillary transverse skeletal gains in young adults undergoing RME. Low evidence suggested that platelet-rich plasma therapy did not minimize the vertical and thickness bone loss after RME in the short term.


CONCLUSIONS
Based on currently available information, the use of low-level laser associated with maxillary expansion seems to provide a more efficient suture opening and bone healing. Limited evidence suggests that osteoperforations improve the skeletal effects of RME in non-growing individuals. There are no adjunctive interventions capable of reducing the periodontal side effects of RME.
['Santana|Lucas Garcia|LG|', 'Marques|Leandro Silva|LS|']
D003729:Dental Care D006801:Humans D008437:Maxilla D010155:Palatal Expansion Technique D013537:Sutures D016896:Treatment Outcome D055815:Young Adult
Rapid maxillary expansion Palatal expansion technique Systematic review