Precise diagnosis of Neisseria macacae infective endocarditis assisted by nanopore sequencing.
Infective endocarditis caused by Neisseria macacae in humans is extremely rare. We presented here a case of N. macacae infective endocarditis in a 61-year-old man with a native aortic valve infection. N. macacae was isolated from blood culture and was detected by nanopore-based metagenomic sequencing in the vegetations. Finally, the patient recovered completely after surgery and antibiotic therapy.
['Ai|Jing-Wen|JW|', 'Liu|Hong|H|', 'Li|Hui-Xia|HX|', 'Ling|Qing-Xia|QX|', 'Ai|Yan-Qin|YQ|', 'Sun|Si-Jia|SJ|', 'Wang|Xuan|X|', 'Zhang|Bing-Yan|BY|', 'Zheng|Jian-Ming|JM|https://orcid.org/0000-0003-1471-9078', 'Jin|Jia-Lin|JL|', 'Zhang|Wen-Hong|WH|']
D000900:Anti-Bacterial Agents D000071997:Blood Culture D004697:Endocarditis, Bacterial D019918:Heart Valve Prosthesis Implantation D006801:Humans D008297:Male D008875:Middle Aged D000081414:Nanopore Sequencing D009343:Neisseria D017422:Sequence Analysis, DNA D016896:Treatment Outcome
Neisseria macacae Infective endocarditis nanopore sequencing Neisseria sp valve replacement