Use of ED and hospital services for patients with acute leukemia after induction therapy: one year follow-up.
Previous studies have documented use of health care services by oncology patients in the Emergency Department (ED), but little is known about the utilization of health services of patients with acute leukemia after induction therapy. The aim of this study was to examine chief reasons for ED and hospital use by patients newly diagnosed with acute leukemia patients after induction therapy up to one year after discharge. A retrospective, longitudinal study of all visits to the ED or unplanned hospital admissions at a single institution for patients with acute leukemia was conducted. Inclusion criteria were patients ≥18 years of age at time of diagnosis, a confirmed diagnosis of AML or ALL, and received and discharged from induction treatment between 2007 and 2010. Donabedian's structure-process-outcome framework guided this study examining health services utilization and assessing patient outcomes. 80 patients met the inclusion criteria; 52 had AML and 28 had ALL; median age was 48 (range: 18-76) and 29% (n=23) were non-Caucasian. 70% (n=56) were discharged from induction in remission. 81% (n=65) had at least 1 ED or hospitalization event, and 44% (n=35) had 2 or more events. Of 137 events in 65 patients, the most common reason was neutropenic fever/infection (55%), bleeding (12%), and GI problems (11%). Mean number of events for ALL was 2.43 compared to 1.33 for AML patients (p=0.02), and 2.23 for <50 years of age compared to 1.20 for those older (p=0.002). 20 patients died within one year of diagnosis. Findings from this study can help inform health services delivery and utilization among patients with acute leukemia after induction therapy. Oncology providers can anticipate discharge needs and enhance follow-up care for those at higher risk for problems needing hospitalization.
['Bryant|Ashley Leak|AL|', 'Deal|Allison M|AM|', 'Walton|AnnMarie|A|', 'Wood|William A|WA|', 'Muss|Hyman|H|', 'Mayer|Deborah K|DK|']
D000293:Adolescent D000328:Adult D000368:Aged D003131:Combined Modality Therapy D004636:Emergency Service, Hospital D005260:Female D005500:Follow-Up Studies D005767:Gastrointestinal Diseases D006470:Hemorrhage D006760:Hospitalization D006801:Humans D015470:Leukemia, Myeloid, Acute D008137:Longitudinal Studies D008297:Male D008875:Middle Aged D009503:Neutropenia D010359:Patient Readmission D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma D011379:Prognosis D012074:Remission Induction D012189:Retrospective Studies D013997:Time Factors D055815:Young Adult
Hospitalization Acute leukemia Induction therapy Emergency Department Health care utilization