Early Oral Antibiotic Switch for Staphylococcus aureus Bacteremia: Many Are Called, but Few Are Chosen.
Staphylococcus aureus bacteremia (SAB) is a complicated, high-risk disease. For selected low-risk SAB, the role of oral antibiotic stepdown therapy is unknown. Bupha-Intr et al. report a retrospective cohort of low-risk SAB patients who did well with a short duration of intravenous antibiotics, followed by an additional ∼10 days of oral antibiotics, primarily using beta-lactams. Prospective trials will help further define the efficacy of this approach.
['Holland|Thomas L|TL|']
D000900:Anti-Bacterial Agents D016470:Bacteremia D006801:Humans D011446:Prospective Studies D012189:Retrospective Studies D013203:Staphylococcal Infections D013211:Staphylococcus aureus D047090:beta-Lactams
Staphylococcus aureus bloodstream infections