Prescription Drugs Used in Insomnia.
The scope of this article is to review the effects on sleep of prescription drugs that are commonly prescribed for chronic insomnia in adults. The following groups are discussed: benzodiazepines and its receptor agonists, the dual orexin receptor antagonist suvorexant, melatonin and its receptor agonists, sedating antidepressants, and antipsychotics. Together with the neurobiologic and pharmacologic properties of these drugs, clinical effects are described, including subjective and objective effects on sleep duration, continuity, and architecture. Medical prescription information is given when available. Recently published American and European guidelines for the treatment of insomnia serve as reference frame.
['Dujardin|Sylvie|S|', 'Pijpers|Angelique|A|', 'Pevernagie|Dirk|D|']
D000818:Animals D015928:Cognitive Behavioral Therapy D006801:Humans D006993:Hypnotics and Sedatives D055553:Prescription Drugs D011619:Psychotropic Drugs D007319:Sleep Initiation and Maintenance Disorders
Prescription drugs Chronic insomnia Pharmacotherapy Sleep-effect