Hysteroscopic Resection of Endometrial Polyps and Assisted Reproductive Technology Pregnancy Outcomes Compared with No Treatment: A Systematic Review.
Endometrial polyps are frequently encountered in the uterine cavity of infertile women. There is much debate regarding the treatment of endometrial polyps in patients who are undergoing assisted reproductive technology (ART). A systematic review was performed by searching PubMed, Embase, and the Cochrane Library for retrospective or prospective studies that compared the effect of hysteroscopic resection of polyps with no treatment on pregnancy outcomes of patients who underwent ART. The primary outcomes were clinical pregnancy, live birth, miscarriage, and implantation rates after ART. Eight studies with a total of 2267 patients were included. The results showed that hysteroscopic resection of endometrial polyps (mean size <2 cm) was associated with an increased rate of clinical pregnancy in patients who underwent intrauterine insemination. No clear benefit was observed for clinical pregnancy, live birth, miscarriage, or implantation rates in patients who underwent in vitro fertilization/intracytoplasmic sperm injection cycles. In conclusion, the effect of hysteroscopic polypectomy on pregnancy outcomes of patients who have undergone ART remains unclear. More prospective, randomized controlled trials are warranted to determine appropriate treatment.
['Zhang|Huixia|H|', 'He|Xueqing|X|', 'Tian|Wenyan|W|', 'Song|Xueru|X|', 'Zhang|Huiying|H|']
D000022:Abortion, Spontaneous D010064:Embryo Implantation D004717:Endometrium D005260:Female D005307:Fertilization in Vitro D006801:Humans D015907:Hysteroscopy D007247:Infertility, Female D050498:Live Birth D064887:Observational Studies as Topic D011127:Polyps D011247:Pregnancy D011256:Pregnancy Outcome D018873:Pregnancy Rate D027724:Reproductive Techniques, Assisted D014591:Uterine Diseases
ART Intrauterine insemination Hysteroscopic polypectomy Live birth rate Pregnancy rate