Morphological and chemical effects of in-office and at-home desensitising agents containing sodium fluoride on eroded root dentin.
OBJECTIVE
The aim of this study was to evaluate the morphological and chemical effect of in-office and at-home desensitising agents containing sodium fluoride (NaF) on eroded root dentine in vitro.


METHODS
Fifty bovine dentine samples were pre-eroded and randomised into five groups (n = 10): G1 (Control) - milli-Q water; G2 - fluoride varnish containing NaF 22,500 ppm; G3 - desensitising cream containing NaF 9,000 ppm associated with 20% nanohydroxyapatite; G4 - toothpaste with NaF 5,000 ppm associated to tricalcium phosphate; G5 - toothpaste containing NaF 900 ppm and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF). The specimens were submitted to erosive challenge for three days. The analyses were performed using non-contact profilometry for volumetric (Sa) and linear roughness (Ra) followed by scanning electron microscopy (SEM) and Energy Dispersive X-ray Spectrometry (EDS). The data were analysed by Kruskal-Wallis and Wilcoxon tests (α = 0.05).


RESULTS
There was a significant reduction of Ra and Sa for the eroded samples from the G2 and G5 (p < 0.05) after an erosive challenge. The dentine surface topography pattern showed partially or totally occluded dentinal tubules after treatments, except in the control group. The control, G4 and G3 groups showed a reduction in the dentine inorganic content percentage of Ca (Calcium) and P (Phosphorus) minerals.


CONCLUSION
The fluoride varnish and CPP-ACPF toothpaste were able to prevent morphological changes and were the only materials that showed the Ca and P content increased after treatment. These materials may be promising alternatives in the clinical control of dentin erosion.
['Alencar|Cristiane de Melo|CM|', 'Leite|Karla Lorene de França|KLF|', 'Ortiz|Mariangela Ivette Guanipa|MIG|', 'Magno|Marcela Baraúna|MB|', 'Rocha|Gustavo Miranda|GM|', 'Silva|Cecy Martins|CM|', 'Maia|Lucianne Cople|LC|']
D000818:Animals D002417:Cattle D003804:Dentin D005459:Fluorides D012969:Sodium Fluoride D014077:Tooth Erosion D014092:Tooth Root D014100:Toothpastes
Sodium fluoride Dentin Remineralisation Tooth erosion