Common Pathogenesis of Acne Vulgaris and Atherosclerosis.
Foam cells are lipid-loaded macrophages and neutrophils that are generated from a massive uptake of oxidized lipid. Foam cells are a pathological hallmark of atherosclerosis, and have also been found in acne lesions. The same pathological changes determine the common pathogenesis. According to the pathological function of foam cells in these lesions, we put forward a viewpoint on the pathogenesis of acne and atherosclerotic plaques.
['Jiang|Hao|H|http://orcid.org/0000-0001-8475-9433', 'Li|Changyi|C|']
D000152:Acne Vulgaris D050197:Atherosclerosis D005487:Foam Cells D006801:Humans D008264:Macrophages D012629:Sebum
acne atherosclerosis foam cells macrophages sebum