DL-mandelic acid intercalated Zn-Al layered double hydroxide: A novel antimicrobial layered material.
DL-mandelic acid (MA) has been intercalated into Zn-Al layered double hydroxide (LDH) by an anion-exchange reaction. After intercalation of MA anions, the basal spacing of the LDH increased from 0.75 to 1.46 nm, suggesting that the MA anions were successfully intercalated into the interlayer galleries of the LDH. The structure and the thermal stability of the samples were characterized by XRD, FT-IR, TG-DTA. Studies of MA release from ZnAl-MA-LDH in hydrochloric solution (pH = 4) imply that ZnAl-MA-LDH is a better controlled release system than pure MA. Meanwhile, the mechanisms of slow release were assessed by using four commonly kinetic models. Finally, the antimicrobial activity of ZnAl-MA-LDH was tested against two kinds of bacteria and a fungus. The study confirms that the mandelic ions intercalated LDHs have the potential application as a slow release preservative in the future.
['Tang|Li-Ping|LP|', 'Cheng|Hui-Min|HM|', 'Cui|Shu-Mei|SM|', 'Wang|Xin-Rui|XR|', 'Song|Li-Ya|LY|', 'Zhou|Wei|W|', 'Li|Shu-Jing|SJ|']
D000535:Aluminum D000890:Anti-Infective Agents D004055:Differential Thermal Analysis D065546:Drug Liberation D006878:Hydroxides D007364:Intercalating Agents D007700:Kinetics D008333:Mandelic Acids D008826:Microbial Sensitivity Tests D013696:Temperature D013818:Thermogravimetry D014961:X-Ray Diffraction D015032:Zinc
DL-mandelic acid Intercalation Layered double hydroxide Antimicrobial Slow release