Early stage primary ovarian mucinous carcinoma: Outcome-based clinicopathological study in comparison with serous carcinoma.
OBJECTIVE
To compare clinicopathological characteristics and survival rates between patients with primary ovarian mucinous carcinoma and those with primary ovarian serous carcinoma.


METHODS
This retrospective study reviewed archival tumour specimens, originally diagnosed as primary ovarian mucinous carcinoma, using refined histological criteria. All patients were contacted to establish survival status. Clinicopathological characteristics and patient survival data were compared with a group of control patients with primary ovarian serous carcinoma.


RESULTS
Of the 33 patients originally diagnosed with primary ovarian mucinous carcinoma, this diagnosis was only confirmed in 18. Primary ovarian mucinous carcinoma was more commonly associated with early International Federation of Gynecology and Obstetrics tumour stages and low-grade histology than primary ovarian serous carcinoma. Patients with primary ovarian mucinous carcinoma had a significantly higher overall 5-year survival rate than those with primary ovarian serous carcinoma (12/12 [100%] versus 14/24 [58%]). Kaplan-Meier survival plots demonstrated that patients with primary ovarian mucinous carcinoma had a survival advantage over patients with primary ovarian serous carcinoma.


CONCLUSIONS
Primary ovarian mucinous carcinomas are frequently low-grade, stage I tumours and have an excellent prognosis.
['Tian|Qifang|Q|', 'Lu|Bingjian|B|', 'Ye|Jing|J|', 'Lu|Weiguo|W|', 'Xie|Xing|X|', 'Wang|Xinyu|X|']
D002288:Adenocarcinoma, Mucinous D000328:Adult D000368:Aged D018284:Cystadenocarcinoma, Serous D005260:Female D005500:Follow-Up Studies D006801:Humans D008875:Middle Aged D060787:Neoplasm Grading D009367:Neoplasm Staging D010051:Ovarian Neoplasms D011379:Prognosis D012189:Retrospective Studies D016019:Survival Analysis
primary Ovarian mucinous carcinoma prognosis surgery