Universal decolonization with hypochlorous solution in a burn intensive care unit in a tertiary care community hospital.
Infections are the leading cause of morbidity and mortality in burn patients. Patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) are at higher risk of developing an invasive infection, and MRSA is endemic in many burn units. The typical decolonization regimen of mupirocin and chlorhexidine bathing is not optimal in burn patients because of chlorhexidine limitations on nonintact skin. We studied the impact of universal decolonization using mupirocin and hypochlorous acid bathing on health care-associated MRSA infections in a burn intensive care unit. We show a significant decrease in total MRSA infections.
['Gray|Dorinne|D|', 'Foster|Kevin|K|', 'Cruz|Abner|A|', 'Kane|Gail|G|', 'Toomey|Mike|M|', 'Bay|Curtis|C|', 'Kardos|Patricia|P|', 'Ostovar|Gholamabbas Amin|GA|']
D000293:Adolescent D000328:Adult D000368:Aged D000369:Aged, 80 and over D000900:Anti-Bacterial Agents D000985:Antisepsis D001494:Baths D002053:Burn Units D002056:Burns D002353:Carrier State D002648:Child D002675:Child, Preschool D005260:Female D006764:Hospitals, Community D006801:Humans D006997:Hypochlorous Acid D007223:Infant D007362:Intensive Care Units D008297:Male D008875:Middle Aged D012189:Retrospective Studies D013203:Staphylococcal Infections D013211:Staphylococcus aureus D063128:Tertiary Healthcare D016896:Treatment Outcome D055815:Young Adult
Universal decolonization hypochlorous acid methicillin-resistant S aureus decolonization methicillin-resistant Staphylococcus aureus infection