Sclerosing bone dysplasias.
The group of sclerosing bone dysplasia's is a clinically and genetically heterogeneous group of rare bone disorders which, according to the latest Nosology and classification of genetic skeletal disorders (2015), can be subdivided in three subgroups; the neonatal osteosclerotic dysplasias, the osteopetroses and related disorders and the other sclerosing bone disorders. Here, we give an overview of the most important radiographic and clinical symptoms, the underlying genetic defect and potential treatment options of the different sclerosing dysplasias included in these subgroups.
['Boudin|Eveline|E|', 'Van Hul|Wim|W|']
D001848:Bone Diseases, Developmental D001842:Bone and Bones D006801:Humans D008403:Mass Screening D010022:Osteopetrosis D012598:Sclerosis
sclerosing bone disorders bone density differential diagnosis hyperostosis osteopetrosis