Four new triterpenes and triterpene glycosides from the leaves of Ilex latifolia and their inhibitory activity on triglyceride accumulation.
Two new triterpenes (1 and 2) and two new triterpene glycosides (3 and 4), along with six known triterpenes (5-10) were isolated from the leaves of Ilex latifolia. The structures of new compounds were elucidated on the basis of NMR, HR-MS, and X-ray diffraction analysis. Compounds 4 and 5 showed potent inhibitory activity on oleic acid/palmitic acid induced triglyceride accumulation on HepG2 cells.
['Wang|Cun-Qin|CQ|', 'Li|Man-Mei|MM|', 'Zhang|Wei|W|', 'Wang|Lei|L|', 'Fan|Chun-Lin|CL|', 'Feng|Rui-Bing|RB|', 'Zhang|Xiao-Qi|XQ|', 'Ye|Wen-Cai|WC|']
D006027:Glycosides D056945:Hep G2 Cells D006801:Humans D030017:Ilex D015394:Molecular Structure D019301:Oleic Acid D019308:Palmitic Acid D018515:Plant Leaves D014280:Triglycerides D014315:Triterpenes
Triterpene Triterpene glycoside Ilex latifolia