Sleep and fatigue after TBI.
BACKGROUND
Whilst post traumatic brain injury fatigue (PTBIF) and sleep disturbance are common sequelae following brain injury, underlying mechanisms, and the potential for targeted interventions remain unclear.


OBJECTIVE
To present a review of recent studies exploring the epidemiology of PTBIF and sleep disturbance, the relationship and neuropsychological correlates of these issues, potential approaches to intervention, and implications for neurorehabilitation.


METHODS
A review of relevant literature was undertaken, with a focus on PTBIF relating to sleep disturbance, the neuropsychological correlates of these issues and implications for neurorehabilitation. This paper does not set out to provide a systematic review.


RESULTS
Multidimensional approaches to assessment and treatment of sleep disturbance and PTBIF are required.


CONCLUSIONS
There is a need for more robust findings in determining the complex nature of relationships between PTBIF, sleep disturbance, and correlates. Longitudinal prospective data is required to increase our understanding of the nature and course of PTBIF and sleep disturbance post TBI. Large scale clinical trials are required in evaluating the potential benefits of interventions.
['Cronin|Heather|H|', "O'Loughlin|Emer|E|"]
D000070642:Brain Injuries, Traumatic D005221:Fatigue D005260:Female D006801:Humans D008297:Male D000066530:Neurological Rehabilitation D011446:Prospective Studies D012890:Sleep D012893:Sleep Wake Disorders
fatigue brain injury Sleep disturbance neuropsychological rehabilitation