Treatment of diabetic kidney disease: current and future targets.
Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease in Korea and worldwide, and is a risk factor for the development of cardiovascular complications. The conventional treatments for DKD are control of blood glucose and blood pressure levels by inhibiting the renin-angiotensin system. However, the prevalence of DKD continues to increase and additional therapies are required to prevent or ameliorate the condition. Many drugs have been, or are being, developed to target the molecular mechanisms in play in DKD. This review focuses on DVD treatment, considering current and emerging therapeutic targets and the clinical trial-based evidence.
['Kim|Mi-Kyung|MK|']
D000959:Antihypertensive Agents D001786:Blood Glucose D001794:Blood Pressure D003928:Diabetic Nephropathies D054873:Dipeptidyl-Peptidase IV Inhibitors D006801:Humans
Diabetes Kidney Therapeutics