Index of Theta/Alpha Ratio of the Quantitative Electroencephalogram in Alzheimer's Disease: A Case-Control Study.
Alzheimer's disease (AD) is a devastating neurodegenerative disorder in human beings associated with cognitive, behavioral and motor impairments. The main symptom of AD is dementia, which causes difficulties in carrying out daily practices. Brain waves are altered in people with AD. Relative indices of brain waves can be beneficial in the diagnosis of AD. In this case-control study, 50 patients with AD and 50 matched healthy individuals were enrolled in case and control groups respectively. With recording and analyzing of brain waves with the utilization of quantitative electroencephalogram (QEEG), index of theta/alpha ratio was assessed in both groups. The index of theta/alpha ratio was significantly higher in patients with AD in comparison to healthy individuals (P<0.05). Index of theta/alpha ratio obtained by QEEG provides a non-invasive diagnostic marker of AD, which may be helpful in identification of non-advanced disease in susceptible individuals.
['Fahimi|Golshan|G|', 'Tabatabaei|Seyed Mahmoud|SM|', 'Fahimi|Elnaz|E|', 'Rajebi|Hamid|H|']
D000368:Aged D000369:Aged, 80 and over D000544:Alzheimer Disease D001921:Brain D016022:Case-Control Studies D004569:Electroencephalography D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D009483:Neuropsychological Tests
Theta/alpha ratio Alzheimer's disease Alpha wave Theta wave