Cutaneous manifestations of peripheral T-cell lymphoma, not otherwise specified: a case series highlighting the diagnostic challenges for this heterogeneous group.
Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a rare, heterogeneous group of nodal and extranodal mature T-cell lymphomas that do not correspond to any of the defined T-cell entities, according to the World Health Organization classification. Most cases present with late stage nodal disease; however extranodal involvement is common. Skin and subcutaneous involvement is reported in approximately 20% of cases. Little attention has been given to the highly variable skin manifestations in the literature. It is our experience that lesions can present in ways other than previously described nodular or tumourous lesions that often ulcerate. We present a case series from a large tertiary institution of seven cases of PTCL, NOS with skin involvement, highlighting the variable presentations and diagnostic challenges for this heterogeneous group.
['Wallett|Arabella|A|', 'Ibbetson|Jan S|JS|', 'Kearney|Daniel|D|', 'Newland|Kate|K|', 'Sidhu|Shireen|S|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D005260:Female D006801:Humans D016410:Lymphoma, T-Cell, Cutaneous D016411:Lymphoma, T-Cell, Peripheral D008297:Male D008875:Middle Aged D012878:Skin Neoplasms D015996:Survival Rate
peripheral T-cell lymphoma lymphoma not otherwise specified skin cutaneous lesion