New approach for phylogenetic tree recovery based on genome-scale metabolic networks.
A wide range of applications and research has been done with genome-scale metabolic models. In this work, we describe an innovative methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this comparison in order to infer evolutionary distances between different organisms. Our methodology allows a quantification of the metabolic differences between different species from a broad range of families and even kingdoms. This quantification is then applied in order to reconstruct phylogenetic trees for sets of various organisms.
['Gamermann|Daniel|D|', 'Montagud|Arnaud|A|', 'Conejero|J Alberto|JA|', 'Urchueguía|Javier F|JF|', 'de Córdoba|Pedro Fernández|PF|']
D000465:Algorithms D001419:Bacteria D019295:Computational Biology D019143:Evolution, Molecular D016680:Genome, Bacterial D053858:Metabolic Networks and Pathways D010802:Phylogeny
networks genome-scale metabolic models connectivity phylogeny