Association Between Prematurity and Diagnosis of Neurodevelopment Disorder: A Case-Control Study.
The aim of this study is to investigate the association between prematurity and diagnosis of neurodevelopmental disorders (ND) (attention deficit/hyperactivity disorder [ADHD] or autism spectrum disorder [ASD]) in Brazilian children and adolescents. Case-control study based on medical records data from a specialized outpatient clinic. Prematurity was defined as gestational age less than 37 weeks. Prematurity was independently associated with diagnosis of a ND (adjusted odds ratio [AOR] 3.46, 95% CI 1.15 - 7.92), as well as with ADHD and ASD diagnosis after a multiple logistic regression analysis. These findings from Brazilian patients are related to what is found in the literature worldwide. Efforts to modify risk factors, such as prematurity, may impact incidence reduction of both ADHD and ASD.
['Soncini|Thaise C B|TCB|', 'Belotto|Gabriella Antunes|GA|', 'Diaz|Alexandre P|AP|']
D000293:Adolescent D001289:Attention Deficit Disorder with Hyperactivity D000067877:Autism Spectrum Disorder D001938:Brazil D016022:Case-Control Studies D002648:Child D005260:Female D006801:Humans D015994:Incidence D008297:Male D016017:Odds Ratio D047928:Premature Birth D012307:Risk Factors
Premature Neurodevelopmental disorders Autism spectrum disorder Attention deficit disorder with hyperactivity Infant