Aquablation of the prostate: single-center results of a non-selected, consecutive patient cohort.
PURPOSE
Aquablation of the prostate using the AquaBeam™ system promises equivalent functional outcomes, reduced learning curve, and improved sexual function compared to transurethral prostate resection as shown in prospective randomized trials. This prospective cohort study aims to evaluate if published results can be transferred into the clinical routine in a non-selected patient collective.


METHODS
This study includes all patients treated between September 2017 and June 2018 with Aquablation of the prostate. Patients have been evaluated prospectively for the perioperative course and early follow-up. Besides voiding parameter and symptom score, TRUS-volume change, ejaculatory function, and adverse events have been recorded.


RESULTS
118 consecutive patients have been treated in the given time. Aquablation could be carried out successfully in all patients. IPSS, QoL, Qmax, and PVR improved significantly after the procedure and continued to improve during 3-month follow-up. Mean OR time was 20 min, TRUS volume decreased by 65%, and 73% of the patients retained antegrade ejaculation. Thirteen adverse events (> Clavien-Dindo I) occurred in 10 patients.


CONCLUSION
The surgical ablation of the prostate using Aquablation achieved significant and immediate improvement of functional voiding parameters Qmax and PVR as well as symptomatic improvement of IPSS and QoL. Aquablation seems to be safe and effective with a low perioperative complication profile even in a non-selected group of patients.
['Bach|T|T|', 'Giannakis|I|I|http://orcid.org/0000-0001-9716-5001', 'Bachmann|A|A|', 'Fiori|C|C|', 'Gomez-Sancha|Fernando|F|', 'Herrmann|T R W|TRW|', 'Netsch|C|C|', 'Rieken|M|M|', 'Scoffone|C M|CM|', 'Tunc|L|L|', 'Rassweiler|J J|JJ|', 'Liatsikos|E|E|']
D055011:Ablation Techniques D000368:Aged D000369:Aged, 80 and over D015331:Cohort Studies D006801:Humans D008297:Male D008875:Middle Aged D011183:Postoperative Complications D011470:Prostatic Hyperplasia D012735:Sexual Dysfunction, Physiological D020728:Transurethral Resection of Prostate D016896:Treatment Outcome D014524:Urethral Obstruction D014867:Water
Aquablation AquaBeam BPH BPO Waterjet