Uterine stem cells--promise and possibilities.
A fraction of cells residing in the uterine endometrium exhibit functional pluripotent potential, allowing them to be classified as adult stem cells. While the physiological relevance of this cell population is mostly conjectural at this juncture, uterine endometrial stem cells (UESC's) may underline pathogenesis of certain common gynecological disorders, such as endometriosis and adenomyosis. The ease of access and harvesting of UESC's and the diverse differentiation potential of this cell population has identified the uterine endometrium as a valuable source of autologous stem cells that can be harnessed through judicious application of principals of regenerative medicine. This mini review offers a glimpse into the journey, and an introduction to the spectrum of disorders that UESC's have the potential of impacting.
['Pal|Lubna|L|']
D053687:Adult Stem Cells D000818:Animals D002454:Cell Differentiation D004715:Endometriosis D004717:Endometrium D005260:Female D006801:Humans D012038:Regeneration
Endometrium Stem cell Uterine stem cell Uterus