Response-adaptive designs for continuous treatment responses in phase III clinical trials: A review.
A variety of response-adaptive randomization procedures have been proposed in literature assuming binary outcomes. However, the list is not so long for continuous outcomes though many real clinical trials deal with continuous treatment responses. In this paper, we attempt to explore the available procedures together with a comparison of their performances. Some real-life adaptive trial is also reviewed.
['Biswas|Atanu|A|', 'Bhattacharya|Rahul|R|']
D056808:Biostatistics D017326:Clinical Trials, Phase III as Topic D003198:Computer Simulation D005260:Female D015658:HIV Infections D006801:Humans D007231:Infant, Newborn D018445:Infectious Disease Transmission, Vertical D015233:Models, Statistical D051474:Neuralgia, Postherpetic D000069583:Pregabalin D011247:Pregnancy D011251:Pregnancy Complications, Infectious D016032:Randomized Controlled Trials as Topic D018709:Statistics, Nonparametric D015215:Zidovudine
Response-adaptive allocation continuous responses covariate delayed response urn model