The Neurobiology of Borderline Personality Disorder.
This article reviews the most salient neurobiological information available about borderline personality disorder (BPD) and presents a theoretic model for what lies at the heart of BPD that is grounded in those findings. It reviews the heritability, genetics, and the biological models of BPD, including the neurobiology of affective instability, impaired interoception, oxytocin and opiate models of poor attachment or interpersonal dysfunction, and structural brain imaging over the course of development in BPD; and posits that the core characteristic of BPD may be an impairment in emotional interoception or alexithymia.
['Perez-Rodriguez|Maria Mercedes|MM|', 'Bulbena-Cabré|Andrea|A|', 'Bassir Nia|Anahita|A|', 'Zipursky|Gillian|G|', 'Goodman|Marianne|M|', 'New|Antonia S|AS|']
D001883:Borderline Personality Disorder D004644:Emotions D006801:Humans D007175:Impulsive Behavior D065812:Interoception D008954:Models, Biological D009446:Neurobiology D059906:Neuroimaging D010121:Oxytocin
Borderline personality disorder Genetics Oxytocin Alexithymia Emotion dysregulation Impulsive aggression Neuroimaging Opioids