Outcomes of percutaneous coronary interventions in cancer patients.
Introduction: There are numerous shared risk factors in the etiopathogenesis of coronary artery disease (CAD) and cancer both at epidemiologic and molecular level. Additionally, different modalities of treatment of cancer such as radiation, chemotherapy, immunotherapy, and hormonal therapies further increase the risk of CAD and acute coronary syndrome. Most large database analysis and single-center experiences have shown that cancer patients undergoing PCI are at an increased risk of in-hospital mortality, bleeding, repeat revascularization.Areas covered: In this review article the authors discuss the associations between CAD and cancer, challenges for PCI in cancer patients and outcome data.Expert opinion: Interventionists performing PCI on cancer patients should be cognizant of the heightened risk of bleeding, thrombosis, possible need for interruption of dual-antiplatelet therapy, and the increased risk of target lesion revascularization in this cohort. These risks may be partially mitigated by utilization of best practices such as the use of radial artery access, intravascular imaging for lesion assessment and stent optimization and avoidance of complex stenting strategies. Finally, it is of paramount importance to have a multidisciplinary approach consisting of the treating cardiologist, medical and/or surgical oncologist, and palliative medicine, and involve the patient and their family in making informed decisions.
['Bharadwaj|Aditya S|AS|', 'Swamy|Pooja M|PM|', 'Mamas|Mamas A|MA|']
D054058:Acute Coronary Syndrome D003324:Coronary Artery Disease D006470:Hemorrhage D017052:Hospital Mortality D006801:Humans D009369:Neoplasms D062645:Percutaneous Coronary Intervention D012307:Risk Factors D015607:Stents D016896:Treatment Outcome
outcomes cancer Coronary artery disease (CAD) percutaneous ﻿coronary interventions (PCI)