Development of a New ICT-Based Multisensor Blood Pressure Monitoring System for Use in Hemodynamic Biomarker-Initiated Anticipation Medicine for Cardiovascular Disease: The National IMPACT Program Project.
We have developed a multisensor home and ambulatory blood pressure (BP) monitoring system for monitoring 24-h central and brachial BP variability concurrent with physical activity (PA), temperature, and atmospheric pressure. The new BP monitoring system utilizes our recently developed biological and environmental signal monitoring Information Communication Technology/Internet of Things system, which can simultaneously monitor the environment (temperature, illumination, etc.) of different rooms in a house (entryway, bedroom, living room, bathing room, and toilet), and a wrist-type high-sensitivity actigraph for identifying the location of patients. By collecting both data on BP and environmental parameters, the system can assess the brachial and central hemodynamic BP reactivity profiles of patients, such as actisensitivity (BP change with PA), thermosensitivity (with temperature), and atmospheric sensitivity (with atmospheric pressure). We used this new system to monitor ambulatory BP variability in outpatients with one or more cardiovascular disease (CVD) risk factors both in summer and winter. Actisensitivity (the slope of the regression line of ambulatory BP against the log-physical activity) was higher in winter than summer. By multi-level analysis using the parameters monitored by this system, we estimated the ambulatory BPs under different conditions. The individual time-series big data collected by this system will contribute to anticipation medicine for CVD.
['Kario|Kazuomi|K|', 'Tomitani|Naoko|N|', 'Kanegae|Hiroshi|H|', 'Yasui|Nobuhiko|N|', 'Nishizawa|Masafumi|M|', 'Fujiwara|Takeshi|T|', 'Shigezumi|Takeya|T|', 'Nagai|Ryozo|R|', 'Harada|Hiroshi|H|']
D062186:Arterial Pressure D001274:Atmospheric Pressure D018660:Blood Pressure Monitoring, Ambulatory D015924:Blood Pressure Monitors D001916:Brachial Artery D002318:Cardiovascular Diseases D004867:Equipment Design D015444:Exercise D006801:Humans D011237:Predictive Value of Tests D011379:Prognosis D015203:Reproducibility of Results D012621:Seasons D013696:Temperature D013997:Time Factors D014160:Transducers, Pressure
Anticipation medicine Physical activity Thermosensitive Time-series big data Ambulatory blood pressure monitoring Blood pressure variability Home blood pressure monitoring Information and communication technology (ICT) Internet of Things (IoT)