Genetic and population analyses of Vibrio parahaemolyticus isolates from three major coastal regions in China.
AIM
This study aims to evaluate the genetic and population structure of Vibrio parahaemolyticus in the major coastal regions of China.


MATERIALS & METHODS
Multilocus sequence typing was performed.


RESULTS
Insertion of large sequence into recA happened in nearly 30 strains, which were untypeable by multilocus sequence typing. A collection of 307 V. parahaemolyticus isolates were typed into 160 sequence types, including 117 novel ones. eBURST analysis revealed five clonal complexes, 11 doublets, and 108 singletons. The 160 sequence types formed two main lineages in the phylogenetic analysis.


CONCLUSION
V. parahaemolyticus along the Chinese coastal regions exhibits high levels of genetic diversity and has undergone significant purifying selection and frequent recombination. A deeper understanding of V. parahaemolyticus genetic diversity could be obtained at the level of genome sequences.
['Li|Ping|P|', 'Xin|Wenwen|W|', 'Kang|Lin|L|', 'Chen|Zhongwen|Z|', 'Guo|Chenyi|C|', 'Gao|Shan|S|', 'Yang|Hao|H|', 'Ji|Bin|B|', 'Yan|Yong|Y|', 'Wang|Henghui|H|', 'Zhou|Dongsheng|D|', 'Yang|Wenhui|W|', 'Wang|Jinglin|J|']
D000483:Alleles D001426:Bacterial Proteins D002681:China D004269:DNA, Bacterial D014644:Genetic Variation D005838:Genotype D006801:Humans D058885:Multilocus Sequence Typing D010802:Phylogeny D011938:Rec A Recombinases D017747:Seafood D012623:Seawater D017422:Sequence Analysis, DNA D014736:Vibrio parahaemolyticus
Vibrio parahaemolyticus China population structure genetic diversity MLST