Concise reviews: Characteristics and potential applications of human dental tissue-derived mesenchymal stem cells.
Recently, numerous types of human dental tissue-derived mesenchymal stem cells (MSCs) have been isolated and characterized, including dental pulp stem cells, stem cells from exfoliated deciduous teeth, periodontal ligament stem cells, dental follicle progenitor cells, alveolar bone-derived MSCs, stem cells from apical papilla, tooth germ progenitor cells, and gingival MSCs. All these MSC-like cells exhibit self-renewal, multilineage differentiation potential, and immunomodulatory properties. Several studies have demonstrated the potential advantages of dental stem cell-based approaches for regenerative treatments and immunotherapies. This review outlines the properties of various dental MSC-like populations and the progress toward their use in regenerative therapy. Several dental stem cell banks worldwide are also introduced, with a view toward future clinical application.
['Liu|Junjun|J|', 'Yu|Fang|F|', 'Sun|Yao|Y|', 'Jiang|Beizhan|B|', 'Zhang|Wenjun|W|', 'Yang|Jianhua|J|', 'Xu|Guo-Tong|GT|', 'Liang|Aibin|A|', 'Liu|Shangfeng|S|']
D000818:Animals D002454:Cell Differentiation D003782:Dental Pulp D003795:Dental Sac D006801:Humans D045164:Mesenchymal Stem Cell Transplantation D059630:Mesenchymal Stem Cells D023822:Tissue Engineering
Mesenchymal stem cells Dental stem cell banks Dental stem cells Cell-based therapy Immunomodulation Tissue regeneration