Posterior reversible encephalopathy syndrome and heart failure tacrolimus-induced after liver transplantation: A case report.
BACKGROUND
Patients undergoing liver transplantation can develop posterior reversible encephalopathy syndrome (PRES) and acute heart failure (HF) in the post-operative period. But PRES with HF caused by tacrolimus has rarely been described.


CASE SUMMAR
A 40-year-old female patient who had a normal preoperative cardiac and neural evaluation developed PRES with acute heart failure tacrolimus-induced after liver transplantation. The challenges associated with both diagnosis and management in the setting of a newly implanted graft are discussed.


CONCLUSION
Tacrolimus can induce neurotoxicity and then cardiac toxicity. Magnetic resonance imaging, echocardiography, and increased brain natriuretic peptide may be predictive of post-operative PRES with acute heart failure. Further investigations are necessary to verify this finding.
['Liu|Jun-Fang|JF|', 'Shen|Tian|T|', 'Zhang|Yun-Tao|YT|']
Posterior reversible encephalopathy syndrome Liver transplantation Case report Tacrolimus Cardiac toxicity Neurologic complications