LINC00473: A novel oncogenic long noncoding RNA in human cancers.
Long noncoding RNAs (lncRNAs) have been found to play essential roles in the occurrence and development of multiple human cancers. Accumulating evidence has shown that LINC00473, an oncogenic lncRNA, is upregulated in various human malignancies and related to poor clinical outcomes. Besides, LINC00473 overexpression can promote cell proliferation, migration, and invasion through multiple potential mechanisms, indicating that it may serve as a novel prognostic biomarker and therapeutic target for human cancers. Here, we reviewed the biological functions, molecular mechanisms, and clinical implications of LINC00473 in human cancers.
['Li|Lingfeng|L|', 'Zhang|Xu|X|', 'Liu|Nian|N|', 'Chen|Xiang|X|', 'Peng|Cong|C|0000-0001-7104-5490']
D000818:Animals D002465:Cell Movement D049109:Cell Proliferation D015972:Gene Expression Regulation, Neoplastic D006801:Humans D009361:Neoplasm Invasiveness D009369:Neoplasms D009857:Oncogenes D062085:RNA, Long Noncoding
LINC00473 long noncoding RNA cancer biomarker