Blood Pressure Variability in Acute Ischemic Stroke: The Role of Early Recanalization.
We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale. In multivariate analyses systolic BP variability in the first 24 h post-stroke showed an association with 3 months clinical outcome in the whole population and non-recanalyzed patients. In recanalyzed patients, BP variability did not show a significant association with functional outcome.
['Martins|Ana Inês|AI|', 'Sargento-Freitas|João|J|', 'Jesus-Ribeiro|Joana|J|', 'Correia|Inês|I|', 'Cardoso|Leila|L|', 'Gomes|João Pedro|JP|', 'Gonçalves|Mariana|M|', 'Costa|Rui|R|', 'Silva|Fernando|F|', 'Galego|Orlando|O|', 'Nunes|César|C|', 'Beato-Coelho|José|J|', 'Varela|Ricardo|R|', 'Machado|Cristina|C|', 'Rodrigues|Bruno|B|', 'Santo|Gustavo C|GC|', 'Cunha|Luís|L|']
D000368:Aged D000369:Aged, 80 and over D001794:Blood Pressure D002545:Brain Ischemia D057510:Endovascular Procedures D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D015999:Multivariate Analysis D020127:Recovery of Function D012189:Retrospective Studies D020521:Stroke D016896:Treatment Outcome
Recanalization Acute stroke Blood pressure fluctuations