Influence of Climate on Google Internet Searches for Pruritus Across 16 German Cities: Retrospective Analysis.
BACKGROUND
The burden of pruritus is high, especially among patients with dermatologic diseases. Identifying trends in pruritus burden and people's medical needs is challenging, since not all affected people consult a physician.


OBJECTIVE
The purpose of this study was to investigate pruritus search behavior trends in Germany and identify associations with weather factors.


METHODS
Google AdWords Keyword Planner was used to quantify pruritus-related search queries in 16 German cities from August 2014 to July 2018. All identified keywords were qualitatively categorized and pruritus-related terms were descriptively analyzed. The number of search queries per 100,000 inhabitants of each city was compared to environmental factors such as temperature, humidity, particulate matter 10 micrometers or less in diameter (PM10), and sunshine duration to investigate potential correlations.


RESULTS
We included 1150 pruritus-related keywords, which resulted in 2,851,290 queries. "Pruritus" (n=115,680) and "anal pruritus" (n=102,390) were the most-searched-for keywords. Nearly half of all queries were related to the category localization, with Berlin and Munich having a comparatively high proportion of people that searched for pruritus in the genital and anal areas. People searched more frequently for information on chronic compared to acute pruritus. The most populated cities had the lowest number of queries per 100,000 inhabitants (Berlin, n=13,641; Hamburg, n=18,303; and Munich, n=21,363), while smaller cities (Kiel, n=35,027; and Freiburg, n=39,501) had the highest. Temperature had a greater effect on search query number (beta -7.94, 95% CI -10.74 to -5.15) than did PM10 (beta -5.13, 95% CI -7.04 to -3.22), humidity (beta 4.73, 95% CI 2.70 to 6.75), or sunshine duration (beta 0.66, 95% CI 0.36 to 0.97). The highest relative number of search queries occurred during the winter (ie, December to February).


CONCLUSIONS
By taking into account the study results, Google data analysis helps to examine people's search frequency, behavior, and interest across cities and regions. The results indicated a general increase in search queries during the winter as well as differences across cities located in the same region; for example, there was a decline in search volume in Saarbrucken, while there were increases in Cologne, Frankfurt, and Dortmund. In addition, the detected correlation between search volume and weather data seems to be valuable in predicting an increase in pruritus burden, since a significant association with rising humidity and sunshine duration, as well as declining temperature and PM10, was found. Accordingly, this is an unconventional and inexpensive method to identify search behavior trends and respective inhabitants' needs.
['Tizek|Linda|L|0000-0002-2749-9791', 'Schielein|Maximilian|M|0000-0003-3767-1337', 'Rüth|Melvin|M|0000-0002-5333-4659', 'Ständer|Sonja|S|0000-0003-3612-7786', 'Pereira|Manuel Pedro|MP|0000-0001-5649-2698', 'Eberlein|Bernadette|B|0000-0003-4509-6491', 'Biedermann|Tilo|T|0000-0002-5352-5105', 'Zink|Alexander|A|0000-0001-9313-6588']
D002947:Cities D002980:Climate D005858:Germany D006801:Humans D020407:Internet D008137:Longitudinal Studies D011537:Pruritus D012189:Retrospective Studies
Internet pruritus weather environment informatics retrospective studies