Granular Cell Tumor of the Pituitary Presenting with Major Intraventricular Hemorrhage.
Granular cell tumors of the pituitary gland are rare, slow-growing lesions arising from the neurohypophysis or pituitary stalk. We describe an extremely rare presentation of a pituitary granular cell tumor mimicking an anterior communicating artery aneurysmal rupture with ventricular hemorrhage. The patient was admitted in a comatose state and underwent urgent bilateral external ventricular drainage. Further diagnostic investigation revealed a sellar tumoral mass with suprasellar extension. No vascular anomalies, hormonal abnormalities, or visual disturbances were observed. Macroscopic complete resection without neurologic impairment was obtained via a right pterional approach. Posthemorrhagic hydrocephalus necessitated ventriculoperitoneal shunt placement, and hormonal substitution for panhypopituitarism was provided. The 5-year follow-up examination showed no tumor recurrence. The clinical course of these benign World Health Organization grade I lesions will normally correspond to nonsecreting pituitary adenomas with an insidious development of visual disturbances, hypopituitarism, or hydrocephalus. Sudden onset with potential catastrophic intratumoral and intraventricular hemorrhage is very uncommon.
['Maenhoudt|Wim|W|', 'Van Dorpe|Jo|J|', 'Vanhauwaert|Dimitri|D|']
D000328:Adult D000074042:Cerebral Intraventricular Hemorrhage D016586:Granular Cell Tumor D006801:Humans D008297:Male D010911:Pituitary Neoplasms
Granular Tumor Pituitary Hemorrhage Ventricular