Immunological biomarkers in dermatomyositis.
Dermatomyositis (DM) is a chronic acquired disorder that affects primarily the muscle and skin. The pathogenesis of DM, as well as methods for monitoring disease activity and predicting response to therapy, are subjects of active research. Studies looking to unveil the pathogenesis of DM have revealed key molecules that are potential biomarkers of disease activity. This article reviews briefly the recently discovered molecules that are candidate immunological biomarkers for diagnosing and monitoring disease activity in DM.
['Olazagasti|Jeannette M|JM|', 'Niewold|Timothy B|TB|', 'Reed|Ann M|AM|']
D015415:Biomarkers D018925:Chemokines D003882:Dermatomyositis D006801:Humans D018482:Muscle, Skeletal D012867:Skin
Biomarkers Dermatomyositis Chemokines Cytokines Toll-like receptors Type I interferon