Toxic shock syndrome - the seven Rs of management and treatment.
Staphylococcal and streptococcal toxic shock syndrome (TSS) are associated with significant morbidity and mortality. There has been considerable progress in understanding the pathophysiology and delineating optimal management and treatment. This article reviews the management of TSS, outlining the 'Seven Rs of Managing and Treating TSS': Recognition, Resuscitation, Removal of source of infection, Rational choice of antibiotics, Role of adjunctive treatment (clindamycin and intravenous immunoglobulin), Review of progress and Reduce risk of secondary cases in close contacts.
['Wilkins|Amanda L|AL|', 'Steer|Andrew C|AC|', 'Smeesters|Pierre R|PR|', 'Curtis|Nigel|N|']
D019468:Disease Management D006801:Humans D012772:Shock, Septic D013203:Staphylococcal Infections D013290:Streptococcal Infections
Clindamycin Intravenous immunoglobulin Contact prophylaxis Staphylococcus aureus Streptococcus pyogenes Superantigen