A misleading cause of pseudo-thymic tumor in ectopic Cushing's syndrome.
A 27-year-old man was referred with typical features of severe Cushing's syndrome. A bilateral adrenalectomy was performed. Three months later, a triangular nodular mediastinal enlargement, evocative of a right anterior thymic tumor, was discovered. Thymectomy was undertaken. Histological examination revealed diffuse thymic hyperplasia with negative immunostaining for adrenocorticotropic hormone. Five years later, a right endobronchial tumor corresponding to a carcinoid tumor was removed.
['Icard|Philippe|P|', 'Heyndrickx|Maxime|M|', 'Galateau-Salle|Françoise|F|', 'Resnik|Yves|Y|']
D000315:Adrenalectomy D000324:Adrenocorticotropic Hormone D000328:Adult D015415:Biomarkers D002276:Carcinoid Tumor D003480:Cushing Syndrome D006801:Humans D006854:Hydrocortisone D008175:Lung Neoplasms D008297:Male D011013:Pneumonectomy D049268:Positron-Emission Tomography D003074:Solitary Pulmonary Nodule D013934:Thymectomy D013952:Thymus Hyperplasia D013997:Time Factors D014057:Tomography, X-Ray Computed D016896:Treatment Outcome D019564:Unnecessary Procedures
ectopic carcinoid tumor ACTH syndrome cushing syndrome thymus hyperplasia thymus neoplasms