Management of patients with sphincter of Oddi dysfunction based on a new classification.
AIM
To propose a new classification system for sphincter of Oddi dysfunction (SOD) based on clinical data of patients.


METHODS
The clinical data of 305 SOD patients documented over the past decade at our center were analyzed retrospectively, and typical cases were reported.


RESULTS
The new classification with two more types (double-duct, biliary-pancreatic reflux) were set up on the basis of the Milwaukee criteria. There were 229 cases of biliary-type SOD, including 192 (83.8%) cases cured endoscopically, and 29 (12.7%) cured by open abdominal surgery, and the remaining 8 (3.5%) cases observed with unstable outcomes. Eight (50%) patients with pancreatic-type SOD were cured by endoscopic treatment, and the remaining 8 patients were cured after open abdominal surgery. There were 19 cases of double-duct-type SOD, which consisted of 7 (36.8%) patients who were cured endoscopically and 12 (63.2%) who were cured surgically. A total of 41 cases were diagnosed as biliary-pancreatic-reflux-type SOD. Twenty (48.8%) of them were treated endoscopically, 16 (39.0%) were treated by open abdominal surgery, and 5 (12.2%) were under observation.


CONCLUSION
The newly proposed SOD classification system introduced in this study better explains the clinical symptoms of SOD from the anatomical perspective and can guide clinical treatment of this disease.
['Gong|Jia-Qing|JQ|', 'Ren|Jian-Dong|JD|', 'Tian|Fu-Zhou|FZ|', 'Jiang|Rui|R|', 'Tang|Li-Jun|LJ|', 'Pang|Yong|Y|']
D000328:Adult D000368:Aged D002760:Cholangiopancreatography, Endoscopic Retrograde D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D012189:Retrospective Studies D009803:Sphincter of Oddi D046628:Sphincter of Oddi Dysfunction D016717:Sphincterotomy, Endoscopic D016896:Treatment Outcome
Sphincter of Oddi dysfunction Classification Treatment Diagnosis