Voltage-gated Sodium Channels in Sensory Information Processing.
Objective & Background: Voltage-gated sodium channels (VGSCs) and potassium channels are critical in the generation of action potentials in the nervous system. VGSCs and potassium channels play important roles in the five fundamental senses of vision, audition, olfaction, taste and touch. Dysfunctional VGSCs are associated with clinical sensory symptoms, such as hyperpselaphesia, parosphresia, and so on. Conclusion: This short review highlights the recent advances in the study of VGSCs in sensory information processing and discusses the potential role of VGSCs to serve as pharmacological targets for the treatment of sensory system diseases.
['Zhou|You|Y|', 'Pan|Ping|P|', 'Tan|Zhi-Yong|ZY|', 'Ji|Yong-Hua|YH|']
D000200:Action Potentials D000818:Animals D006801:Humans D009474:Neurons D015221:Potassium Channels D012677:Sensation D012678:Sensation Disorders D061566:Voltage-Gated Sodium Channels
Voltage-gated sodium channel information processing action potential pharmacological membrane protein complexes central
nervous system.