How genomics is contributing to the fight against artemisinin-resistant malaria parasites.
Plasmodium falciparum, the malignant malaria parasite, has developed resistance to artemisinin, the most important and widely used antimalarial drug at present. Currently confined to Southeast Asia, the spread of resistant parasites to Africa would constitute a public health catastrophe. In this review we highlight the recent contributions of genomics to our understanding how the parasite develops resistance to artemisinin and its derivatives, and how resistant parasites may be monitored and tracked in real-time, using molecular approaches.
['Cravo|Pedro|P|', 'Napolitano|Hamilton|H|', 'Culleton|Richard|R|']
D000349:Africa D000818:Animals D000962:Antimalarials D037621:Artemisinins D001210:Asia, Southeastern D004351:Drug Resistance D023281:Genomics D006801:Humans D016778:Malaria, Falciparum D010963:Plasmodium falciparum
Genomics Malaria Plasmodium falciparum Artemisinin resistance Molecular markers