Neuroimaging findings in first unprovoked seizures: a multicentric study in tehran.
OBJECTIVE
Seizure is an emergency in pediatrics. It really matters to the parents of the involved child to have information about the causes, management and prognosis. First unprovoked seizures (FUS) are seizures that occur in patients without fever, trauma or infection. Due to the rapid improvement in diagnostic techniques in the last few decades, the etiology will be revealed and this term will no longer exist. This Study was designed to evaluate brain imaging findings in FUS patients.


MATERIALS & METHODS
Ninety-six children with FUS, who were admitted in three major children's hospitals in Tehran, underwent brain imaging and were enrolled into the study. The decision about the type of imaging (CT or MRI) was based on the patient's medical and financial conditions. An expert radiologist in the field of pediatric neuroimaging interpreted the images.


RESULTS
Altogether, 27.1% had abnormal findings of which 29.2% were in the brain MRI group and 14.3% were in the brain CT scan group. Abnormal results were gliosis (10.4%), hemorrhage (4.2%), dysgenesis (2.1%), dysmyelination (7.3%), encephalomalacy (1%), atrophy (5.2%) and infarction (2.1%). In some patients, the lesions were in 2 or 3 sites and some had more than one type of lesion. There was no association between the duration, age and type of seizure and imaging abnormlities. However, we found an association between the location of the lesion and the type of seizure.


CONCLUSION
We recommend brain imaging in all patients with FUS and apart from some exceptions, brain MRI is superior to CT.
['Molla Mohammadi|Mohsen|M|', 'Tonekaboni|Seyed Hassan|SH|', 'Khatami|Alireza|A|', 'Azargashb|Eznollah|E|', 'Tavasoli|Azita|A|', 'Javadzadeh|Mohsen|M|', 'Zamani|Gholamreza|G|']
First Unprovoked Seizure Seizure Brain Imaging