COVID-19 case fatality rate and tuberculosis in a metropolitan setting.
In this study, we aimed to assess the relationship between tuberculosis case rate and COVID-19 case fatality rate (CFR) among districts within a tuberculosis-endemic metropolitan area. We analyzed data from 43 districts in Lima, Peru. We used districts as the units of observation. Linear regressions were used to investigate the relationship between COVID-19 CFRs and tuberculosis case rates. The mean COVID-19 CFR in each district for reporting Weeks 5-32 was used as the dependent variable. Independent variable was the mean rate of confirmed pulmonary tuberculosis cases for 2017-2019 period. Analyses were adjusted by population density, socioeconomic status, crowded housing, health facility density, and case rates of hypertension, diabetes mellitus, and HIV infection. The mean COVID-19 CFR in Lima was 4.0% ± 1.1%. The mean tuberculosis rate was 16.0 cases per 10,000 inhabitants. In multivariate analysis, tuberculosis case rate was associated with COVID-19 CFR (β = 1.26; 95% confidence interval: 0.24-2.28; p = .02), after adjusting for potential confounders. We found that Lima districts with a higher burden of tuberculosis exhibited higher COVID-19 CFRs, independent of socioeconomic, and morbidity variables.
['Rojas-Bolivar|Daniel|D|http://orcid.org/0000-0003-0585-4155', 'Intimayta-Escalante|Claudio|C|https://orcid.org/0000-0003-2552-9974', 'Cardenas-Jara|Ariana|A|https://orcid.org/0000-0002-4408-5769', 'Jandarov|Roman|R|https://orcid.org/0000-0003-2145-045X', 'Huaman|Moises A|MA|https://orcid.org/0000-0002-6839-5809']
D000086382:COVID-19 D002947:Cities D006801:Humans D016014:Linear Models D010568:Peru D014397:Tuberculosis, Pulmonary
COVID-19 case fatality rate tuberculosis Peru