Spontaneous pneumothorax associated with talc pulmonary granulomatosis after cocaine inhalation.
We report a case of recurrent spontaneous pneumothorax in a patient with cocaine abuse through inhalation alone. He underwent thoracoscopic apical lung resection with mechanical pleurodesis. Despite the lack of significant radiological features of talc induced pulmonary granulomatosis, pathological findings showed granulomas with foreign materials suggestive of being talc. Electronic microscopy showed that the size of talc particles were <4.0 µm and thus small enough to reach the alveoli.
['Fiorelli|Alfonso|A|', 'Accardo|Marina|M|', 'Rossi|Francesco|F|', 'Santini|Mario|M|']
D000280:Administration, Inhalation D000328:Adult D003042:Cocaine D019970:Cocaine-Related Disorders D005547:Foreign Bodies D006801:Humans D008171:Lung Diseases D008297:Male D011030:Pneumothorax D012008:Recurrence D013627:Talc D014057:Tomography, X-Ray Computed
Pneumothorax Talc Granulomatosis Cocaine Lung