Fat-forming solitary fibrous tumor of the kidney: a case report and literature review.
Fat-forming solitary fibrous tumor (SFT) is a rare soft tissue tumor. Herein, we reported a 30-year-old woman was found to have a solid mass measuring 60×45 mm in the right kidney on an abdominal computed tomography scan. The tumor was well-circumscribed and composed of cellular nodules with the classic SFT admixed with clusters and lobules of mature adipocytes. Immunohistochemistry staining showed that the tumor cells were diffusely and strongly positive for CD34 and Bcl-2, focally and weakly positive for CD99 and EMA. Mature adipocytes were positive for S-100 protein. Ki-67 expression was found in approximately 2% of tumor cells. However, tumor cells were negative for cytokeratin, S-100 protein, HMB-45, Melan-A, SMA, and CD117. We made the pathological diagnosis of fat-forming SFT of the right kidney. The differential diagnosis includes angiomyolipoma, liposarcoma, spindle cell lipoma, sarcomatoid renal cell carcinoma, synovial sarcoma, and gastrointestinal stromal tumor. The patient was alive and well without evidence of recurrence or metastasis at 19 months after tumor resection.
['Chen|Yanyang|Y|', 'Wang|Fen|F|', 'Han|Anjia|A|']
D000273:Adipose Tissue D000328:Adult D014408:Biomarkers, Tumor D001706:Biopsy D003937:Diagnosis, Differential D005260:Female D006801:Humans D007150:Immunohistochemistry D007680:Kidney Neoplasms D009392:Nephrectomy D011237:Predictive Value of Tests D054364:Solitary Fibrous Tumors D013997:Time Factors D014057:Tomography, X-Ray Computed D016896:Treatment Outcome D047368:Tumor Burden
Fat-forming solitary fibrous tumor kidney