Subconjunctival bevacizumab and argon laser photocoagulation for preexisting neovascularization following deep lamellar anterior keratoplasty.
We report a rare case of deep anterior lamellar keratoplasty (DALK) neovascularization managed with combination of subconjunctival bevacizumab and argon laser photocoagulation. A 24 year old male underwent Deep anterior lamellar keratoplasty for corneal stromal opacity following presumed viral keratitis. Deep corneal neovascularization was observed postoperatively which was successfully managed using a combination of subconjunctival bevacizumab and argon laser photocoagulation within one week of DALK. The neovascularization resolved by 3 months and at 2 years follow up, patient maintained good visual acuity of 6/12 Snellen's without recurrence of vascularization. A combination of bevacizumab and argon laser may be an effective approach to manage neovascularisation in the immediate postoperative phase (Post DALK) and improve graft survival.
['Lakshmipathy|Meena|M|', 'Susvar|Pradeep|P|', 'Popet|Kshama|K|', 'Rajagopal|Rama|R|']
D020533:Angiogenesis Inhibitors D000068258:Bevacizumab D003228:Conjunctiva D016510:Corneal Neovascularization D006085:Graft Survival D006801:Humans D007267:Injections D007634:Keratitis D015948:Keratoplasty, Penetrating D053685:Laser Therapy D054018:Lasers, Excimer D008297:Male D040262:Receptors, Vascular Endothelial Growth Factor D041623:Tomography, Optical Coherence D014792:Visual Acuity D055815:Young Adult
subconjunctival bevacizumab Argon laser photocoagulation deep anterior lamellar keratoplasty corneal neovascularization corneal scar