Prevalence and clinical characteristics of adrenal incidentalomas in potential kidney donors.
BACKGROUND
The prevalence of adrenal incidentalomas (AIs) in asymptomatic individuals is unknown. This study evaluated the prevalence of AIs in healthy kidney donors in whom pre-operative computed tomography (CT) is performed routinely.


METHODS
All potential kidney donors evaluated at the Rabin Medical Center who had routine abdominal CT were identified and their medical records were retrospectively reviewed. Subjects who had normal CT scans were compared with those with a finding of an AI, evaluating demographic (age, body mass index, systolic and diastolic blood pressure) and laboratory variables (glucose, sodium, potassium, calcium, phosphorus, albumin and creatinine). In addition, prevalence of hypertension, rate of donation and surgical mortality were compared between the two groups.


RESULTS
CT was performed in 673 potential kidney donors. Of these, 645 had a normal CT and 28 (4.2%) had evidence of an AI. Those with AIs had a similar prevalence of hypertension, kidney donation and surgical mortality as those with a normal CT. Those with AIs were older (50.93 ± 11.1 versus 43.76 ± 11.1 years) but other demographic variables were similar; laboratory variables were also similar except for slightly lower albumin and creatinine in those with AIs.


CONCLUSIONS
The prevalence of AIs is high even in healthy asymptomatic individuals.
['Grossman|Alon|A|', 'Koren|Ronit|R|', 'Tirosh|Amit|A|', 'Michowiz|Rachel|R|', 'Shohat|Zippora|Z|', 'Rahamimov|Ruth|R|', 'Mor|Eytan|E|', 'Shimon|Ilan|I|', 'Robenshtok|Eyal|E|']
D000310:Adrenal Gland Neoplasms D000328:Adult D000368:Aged D005260:Female D006801:Humans D016030:Kidney Transplantation D019520:Living Donors D008297:Male D008875:Middle Aged D061330:Multidetector Computed Tomography D015995:Prevalence D055815:Young Adult
Adrenal incidentaloma kidney donors