Prevalence of alcohol use disorder among individuals who binge eat: a systematic review and meta-analysis.
BACKGROUND AND AIMS
Binge eating disorder (BED) is correlated with substance use. This study aimed to estimate the life-time prevalence of alcohol use disorder (AUD) among individuals with non-compensatory binge eating and determine whether their life-time prevalence of AUD is higher than in non-bingeing controls.


DESIGN
A systematic search of databases (PubMed, Embase and Web of Science) for studies of adults diagnosed with BED or a related behavior that also reported the life-time prevalence of AUD was conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol was followed. The protocol was registered on the International Prospective Register of Systematic Reviews (PROSPERO).


SETTING
Studies originating in Canada, Sweden, the United Kingdom and the United States.


PARTICIPANTS
Eighteen studies meeting the inclusion criteria were found, representing 69 233 individuals.


MEASUREMENTS
Life-time prevalence of AUD among individuals with binge eating disorder and their life-time relative risk of AUD compared with individuals without this disorder.


RESULTS
The pooled life-time prevalence of AUD in individuals with binge eating disorder was 19.9% [95% confidence interval (CI) = 13.7-27.9]. The risk of life-time AUD incidence among individuals with binge eating disorder was more than 1.5 times higher than controls (relative risk = 1.59, 95% CI = 1.41-1.79). Life-time AUD prevalence was higher in community samples than in clinical samples (27.45 versus 14.45%, P = 0.041) and in studies with a lower proportion of women (β = -2.2773, P = 0.044).


CONCLUSIONS
Life-time alcohol use disorder appears to be more prevalent with binge eating disorder than among those without.
['Bogusz|Krzysztof|K|0000-0002-2143-0873', 'Kopera|Maciej|M|0000-0001-8526-9778', 'Jakubczyk|Andrzej|A|0000-0001-8714-0118', 'Trucco|Elisa M|EM|0000-0002-9922-8608', 'Kucharska|Katarzyna|K|0000-0002-6130-0520', 'Walenda|Anna|A|0000-0002-8353-0159', 'Wojnar|Marcin|M|0000-0001-5138-9050']
D000328:Adult D000437:Alcoholism D056912:Binge-Eating Disorder D002170:Canada D005260:Female D006801:Humans D015994:Incidence D008297:Male D008875:Middle Aged D015995:Prevalence D012306:Risk D013548:Sweden D006113:United Kingdom D014481:United States
alcohol use disorder systematic review meta-analysis binge eating disorder Alcohol abuse alcohol dependence