Seroprevalence and associated risk factors of Mycoplasma agalactiae and investigation of coinfection with the caprine lentivirus in Rio Grande do Norte, Brazil.
Contagious agalactia is a disease caused by Mycoplasma agalactiae that leads to a reduction or complete stop of milk production. Caprine arthritis encephalitis (CAE) is an infectious disease caused by a lentivirus of the Retroviridae family, member of the small ruminant lentivirus (SRLV) group. Although these diseases are caused by distinct pathogens, the clinical presentation is similar. Hence, this study aimed to perform a serological investigation, as well as to assess correlation between both diseases and risk factors associated in two mesoregions of Rio Grande do Norte, Brazil. Enzyme-linked immunosorbent assay (ELISA) was used for contagious agalactia and western blot for CAE. A total of 538 serum samples were used in this study that were collected from goats and sorted from a blood bank of the Brazilian Agricultural Research Corporation. Seroprevalence of M. agalactiae in flocks from Rio Grande do Norte was 7.8% (42/538). In both regions that were investigated, 25.9% (14/54) of farms had positive animals. CAE results revealed that 3.9% (21/538) of animals and 42.6% (23/54) of farms had this disease. Concerning risk factors, only sex and animal category presented significant relevance (P < 0.05) for contagious agalactia, in which females presented higher frequency of seropositive individuals (10.1%; 39/387). In the animal category, 4.3% (14/326) and 11.1% (36/323) of female breeders were positive for CAE and contagious agalactia, respectively, and significance was identified only in the latter (P < 0.05). In conclusion, there was no correlation between the investigated diseases, considering that no animal demonstrated antibodies for both pathogens.
['Damasceno|Edgar Marques|EM|', 'Pinheiro|Raymundo Rizaldo|RR|', 'Andrioli|Alice|A|', 'Alves|Francisco Selmo Fernandes|FSF|', 'Lima|Ana Milena César|AMC|', 'Peixoto|Renato Mesquita|RM|http://orcid.org/0000-0003-1338-0949', 'Araújo|Juscilânia Furtado|JF|', 'Damasceno|Mariana Siqueira|MS|', 'Brandão|Iane Sousa|IS|']
D000818:Animals D016088:Arthritis-Encephalitis Virus, Caprine D001938:Brazil D060085:Coinfection D004797:Enzyme-Linked Immunosorbent Assay D005260:Female D015511:Goat Diseases D006041:Goats D016180:Lentivirus Infections D008297:Male D009175:Mycoplasma Infections D045644:Mycoplasma agalactiae D012307:Risk Factors D016036:Seroepidemiologic Studies
Contagious agalactia SRLV Diagnosis Prevalence