Clinical characteristics of bacteremia caused by hypermucoviscous Klebsiella pneumoniae at a tertiary hospital.
This study aimed to assess the predictive factors of bacteremia due to hypermucoviscous Klebsiella pneumoniae (hvKP), as well as the mortality. The medical records of 114 patients with K. pneumoniae bacteremia who were divided into the hvKP (n = 24) and non-hvKP (n = 90) groups and were retrospectively reviewed. The male-to-female ratio, age, and underlying disease did not differ between the 2 groups. Mortality was higher among patients in the hvKP bacteremia group than in the non-hvKP bacteremia group (29.2% vs 6.7%). Multivariate analysis showed that the independent predictors associated with hvKP bacteremia were abscess (P = 0.01) and no antibiotic exposure (P = 0.02); thus, early assessment of these conditions is important. For patients with a history of abscess and no antibiotic exposure, it is necessary to administer treatment while keeping the risk of hvKP in mind.
['Namikawa|Hiroki|H|', 'Yamada|Koichi|K|', 'Sakiyama|Arata|A|', 'Imoto|Waki|W|', 'Yamairi|Kazushi|K|', 'Shibata|Wataru|W|', 'Yoshii|Naoko|N|', 'Niki|Makoto|M|', 'Nakaie|Kiyotaka|K|', 'Oinuma|Ken-Ichi|KI|', 'Tsubouchi|Taishi|T|', 'Niki|Mamiko|M|', 'Tochino|Yoshihiro|Y|', 'Takemoto|Yasuhiko|Y|', 'Kaneko|Yukihiro|Y|', 'Shuto|Taichi|T|', 'Kakeya|Hiroshi|H|']
D000368:Aged D000900:Anti-Bacterial Agents D016470:Bacteremia D005260:Female D006801:Humans D007564:Japan D007710:Klebsiella Infections D007711:Klebsiella pneumoniae D008297:Male D008826:Microbial Sensitivity Tests D012189:Retrospective Studies D012307:Risk Factors D062606:Tertiary Care Centers D037521:Virulence Factors
Bacteremia Hypermucoviscous Klebsiella pneumoniae Mortality Abscess Antibiotic exposure