Synchronous Multifocal Canalicular Adenomas.
Canalicular adenoma (CAD) is an uncommon benign tumor of minor salivary glands with predilection for the upper labial mucosa. An 80-year-old female presented with nine submucosal nodules of the upper labial mucosa and bilateral buccal mucosa. Histopathologic examination revealed multifocal circumscribed tumor islands with a tubular growth pattern within a loose hypocellular myxoid background stroma. Interconnecting rows of columnar tumor cells imparted a canalicular morphology. In addition to the characteristic histopathologic findings, a comprehensive immunohistochemical panel supported a final diagnosis of multifocal CAD. Synchronous multifocality in CAD is an infrequent finding and this sine qua non clinicopathologic correlation article exemplifies such a case.
['Sultan|Ahmed S|AS|', 'Chang|Frank S-C|FS|', 'Cooper|Tom|T|', 'Jessri|Maryam|M|http://orcid.org/0000-0002-5333-0623']
Multifocal canalicular adenoma Minor salivary glands Benign salivary gland tumour