Progress toward laboratory containment of poliovirus after polio eradication.
BACKGROUND
The first steps (phase 1) toward laboratory containment of poliovirus after eradication are a national survey of biomedical facilities and a global inventory of such facilities retaining wild poliovirus (WPV) infectious and potentially infectious materials.


METHODS
We reviewed published reports on national laboratory surveys and inventories of WPV materials from each of the 3 polio-free World Health Organization (WHO) regions (the European Region, completed in 2006; the Western Pacific Region, completed in 2008; and the Region of the Americas, completed in 2010), as well as reports on progress in polio-free countries of the remaining 3 regions (the African Region, the Eastern Mediterranean Region, and the WHO South-East Asia Region).


RESULTS
Containment phase 1 activities are complete in 154 of 194 WHO Member States (79%), including all countries and areas of the polio-free regions and most polio-free countries in the remaining 3 regions. A reported 227 209 biomedical facilities were surveyed, with 532 facilities in 45 countries identified as retaining WPV-associated infectious or potentially infectious materials.


CONCLUSIONS
Completion of containment phase 1 global activities is achievable within the time frame set by the Polio Eradication and Endgame Strategic Plan 2013-2018.
['Wolff|Christopher|C|', 'Roesel|Sigrun|S|', 'Lipskaya|Galina|G|', 'Landaverde|Mauricio|M|', 'Humayun|Asghar|A|', 'Withana|Nalini|N|', 'Ramamurty|Nalini|N|', 'Tomori|Oyewale|O|', 'Okiror|Samuel Oumo|SO|', 'Salla|Mbaye|M|', 'Dowdle|Walter|W|']
D000569:Americas D001208:Asia D001210:Asia, Southeastern D019411:Clinical Laboratory Techniques D003264:Containment of Biohazards D060740:Disease Eradication D006801:Humans D019083:Mediterranean Region D011051:Poliomyelitis D017955:Poliovirus D011309:Preservation, Biological
laboratory containment poliovirus polio eradication OPV cessation polio endgame