Colorectal cancer in inflammatory bowel disease: results of the 3rd ECCO pathogenesis scientific workshop (I).
Epidemiological studies demonstrate an increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD). A detailed literature review was conducted on epidemiology, risk factors, pathophysiology, chemoprevention and outcomes of colorectal cancer (CRC) in IBD as part of the 3rd ECCO scientific pathogenesis workshop.
['Sebastian|Shaji|S|', 'Hernández|Vincent|V|', 'Myrelid|Pär|P|', 'Kariv|Revital|R|', 'Tsianos|Epameinondas|E|', 'Toruner|Murat|M|', 'Marti-Gallostra|Marc|M|', 'Spinelli|Antonino|A|', 'van der Meulen-de Jong|Andrea E|AE|', 'Yuksel|Elif Sarıtas|ES|', 'Gasche|Christoph|C|', 'Ardizzone|Sandro|S|', 'Danese|Silvio|S|']
D017668:Age of Onset D016588:Anticarcinogenic Agents D015209:Cholangitis, Sclerosing D003093:Colitis, Ulcerative D015179:Colorectal Neoplasms D003226:Congresses as Topic D003424:Crohn Disease D005492:Folic Acid D006801:Humans D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors D007155:Immunologic Factors D019804:Mesalamine D012307:Risk Factors D015996:Survival Rate D013997:Time Factors D014580:Ursodeoxycholic Acid
Colorectal cancer Inflammatory bowel disease Pathogenesis Epidemiology IBD Chemoprevention Outcomes CRC 5-ASA 5-amino salicylic acid AOM Azoxymethane CAC CD CIN Chromosomal instability Colitis-associated cancer Crohn's disease DSS Dextran sodium sulphate IC IL Indeterminate colitis Interleukins MRR MSI Microsatellite instability Mortality rate ratio NF-κB Nuclear factor-κB OR Odds ratio PSC Primary sclerosing cholangitis RR Relative risk SIR Standardised incidence ratio TGFβ TLR TNFα Toll-like receptor Transforming growth factor-β Tumour necrosis factor-α UC Ulcerative colitis