Incidence and risk factors for suicide death in male patients with genital-system cancer in the United States.
BACKGROUND
A diagnosis of cancer is associated with increased risks of suicidal ideation and suicide attempts. Genital-system cancer comprises nearly a third of all cancers in males. We used the SEER database to identify the incidence of and risk factors for suicide death in male patients with genital-system cancer in the United States.


METHOD
Patients were selected from the SEER database, and X-tile software was used to find the best cutoffs for stratifying age. Logistic regression was used to identify independent risk factors for suicide death. Only variables that were statistically significant in the univariate logistic regression models were analyzed in multivariate logistic regression models.


RESULT
This study found that age (18-66 vs ≥ 76 years: OR = 3.300, P < 0.001; 67-75 vs ≥ 76 years: OR = 1.832, P < 0.001), being unmarried (OR = 1.332, P = 0.010), being divorced, separated, or widowed (OR = 1.338, P = 0.002), caucasian (OR = 2.074, P = 0.003) and not receiving surgery or having an unknown surgery status (OR = 1.405, P < 0.001) significantly increased the risk of suicide death. A particularly important finding was that a time of <1 year after the diagnosis was related to an increased risk of suicide death (<1 vs ≥ 10 years: OR = 1.761, P = 0.008).


CONCLUSION
We found that a number of factors significantly increased the risk of suicide. Importantly, a time of <1 year after the diagnosis was related to an increased risk of suicide death, which indicates the importance of identifying and treating people at risk of suicide as early as possible. These can help clinicians to understand suicidal patients and provide them with appropriate support.
['Yang|Jin|J|', 'He|Gonghao|G|', 'Chen|Siying|S|', 'Pan|Zhenyu|Z|', 'Zhang|Jun|J|', 'Li|Yuanjie|Y|', 'Lyu|Jun|J|']
D000293:Adolescent D000328:Adult D000368:Aged D002423:Cause of Death D005500:Follow-Up Studies D005834:Genital Neoplasms, Male D006801:Humans D015994:Incidence D008297:Male D017533:Marital Status D008875:Middle Aged D012189:Retrospective Studies D018570:Risk Assessment D012307:Risk Factors D018426:SEER Program D013406:Suicide, Attempted D014481:United States D055815:Young Adult
Incidence Risk factors Suicide Genital-system cancer SEER