Prognostic Value of Tricuspid Valve Geometry and Leaflet Coaptation Status in Patients Undergoing Tricuspid Annuloplasty: A Three-Dimensional Echocardiography Study.
BACKGROUND
The advent of three-dimensional echocardiography (3DE) enables detailed evaluation of the tricuspid valve (TV) apparatus; nonetheless, the clinical value of preoperative 3DE is unknown in patients undergoing tricuspid annuloplasty (TA). The aim of this study was to evaluate the prognostic value of TV geometric parameters and leaflet coaptation status evaluated by 3DE in patients undergoing TA.


METHODS
A total of 122 patients who underwent TA during left-sided heart valve surgery were prospectively evaluated. Detailed 3DE was performed before surgery. Adverse outcome was defined as the occurrence of heart failure requiring hospital admission or all-cause mortality following TA.


RESULTS
A total of 33 adverse events (17 heart failures and 16 deaths) occurred during a median follow-up of 36 months. Tethering volume (hazard ratio = 1.32; 95% CI = 1.05-1.66; P = .01) and ratio of total leaflet length to closure length (hazard ratio = 1.07; 95% CI = 1.03-1.12; P < .01) were associated with adverse events after adjustment for age, sex, and tricuspid regurgitation vena contracta width. Receiver-operator characteristic curve analysis revealed that tethering volume (area under curve = 0.73) and ratio of total leaflet length to closure length (area under curve = 0.75) were most associated with adverse events at 1-year follow-up. The presence of either a large tethering volume or a low ratio of total leaflet length to closure length was predictive of an adverse outcome 1 year following TA.


CONCLUSIONS
Our study suggests that 3DE-derived TV tethering volume and ratio of total leaflet length to closure length are important preoperative measures associated with adverse events in patients undergoing TA.
['Chen|Yan|Y|', 'Liu|Ying-Xian|YX|', 'Yu|Yu-Juan|YJ|', 'Wu|Mei-Zhen|MZ|', 'Lam|Yui-Ming|YM|', 'Sit|Ko-Yung|KY|', 'Chan|Daniel Tai-Leung|DT|', 'Ho|Cally Ka-Lai|CK|', 'Ho|Lai-Ming|LM|', 'Fang|Li-Gang|LG|', 'Zhang|Shu-Yang|SY|', 'Lau|Chu-Pak|CP|', 'Au|Wing-Kuk|WK|', 'Tse|Hung-Fat|HF|', 'Yiu|Kai-Hang|KH|']
D000368:Aged D058385:Cardiac Valve Annuloplasty D015331:Cohort Studies D019560:Echocardiography, Three-Dimensional D005260:Female D005500:Follow-Up Studies D006801:Humans D008297:Male D008875:Middle Aged D015588:Observer Variation D011446:Prospective Studies D012372:ROC Curve D018570:Risk Assessment D016896:Treatment Outcome D014261:Tricuspid Valve D014262:Tricuspid Valve Insufficiency
Tricuspid valve geometry Tricuspid annuloplasty Three-dimensional echocardiography Tricuspid regurgitation