Overview of research on Bombyx mori microRNA.
MicroRNAs (miRNAs) constitute some of the most significant regulatory factors involved at the post-transcriptional level after gene expression, contributing to the modulation of a large number of physiological processes such as development, metabolism, and disease occurrence. This review comprehensively and retrospectively explores the literature investigating silkworm, Bombyx mori L. (Lepidoptera: Bombicidae), miRNAs published to date, including discovery, identification, expression profiling analysis, target gene prediction, and the functional analysis of both miRNAs and their targets. It may provide experimental considerations and approaches for future study of miRNAs and benefit elucidation of the mechanisms of miRNAs involved in silkworm developmental processes and intracellular activities of other unknown non-coding RNAs.
['Wang|Xin|X|', 'Tang|Shun-ming|SM|', 'Shen|Xing-jia|XJ|']
D000818:Animals D012831:Bombyx D020869:Gene Expression Profiling D005786:Gene Expression Regulation D035683:MicroRNAs
review silkworm expression profiling analysis target gene prediction microarray technology