Obesity and postoperative atrial fibrillation in patients undergoing cardiac surgery: Systematic review and meta-analysis.
INTRODUCTION
Post-operative atrial fibrillation (POAF) is one of the most common complications following cardiac surgery. However, it is unclear whether there is a relationship between obesity and POAF. We thus assessed all available evidence investigating the association between obesity and POAF, also considering any link between POAF and other post-operative conditions such as mortality, stroke, myocardial infarctions and respiratory complications.


METHODS
Five electronic databases were searched and relevant studies were identified. Data was extracted and meta-analyzed from the identified studies.


RESULTS
We found that obese patients had significantly higher odds of POAF when compared with non-obese patients (P=0.006). There was also significant heterogeneity among the identified studies. POAF when compared with no-POAF was associated with an increased risk of stroke (P<0.0001), 30-day mortality (P=0.005) and respiratory complications (P<0.00001). However, we found no significant link between POAF and myocardial infarctions (P=0.79).


CONCLUSIONS
Our findings suggest that obesity is associated with a moderately higher risk of POAF. While POAF is also associated with an increased incidence of stroke, 30-day mortality and respiratory complications, further studies must be conducted before conclusions can be made about the long-term outcomes.
['Phan|Kevin|K|', 'Khuong|Jacqueline Nguyen|JN|', 'Xu|Joshua|J|', 'Kanagaratnam|Aran|A|', 'Yan|Tristan D|TD|']
D001281:Atrial Fibrillation D006348:Cardiac Surgical Procedures D002318:Cardiovascular Diseases D016206:Databases, Bibliographic D005260:Female D006801:Humans D008297:Male D009765:Obesity D011184:Postoperative Period D012307:Risk Factors
Obesity Postoperative atrial fibrillation Atrial fibrillation AF Body mass index