Interactions of dietary fiber bound antioxidants with hydroxycinnamic and hydroxybenzoic acids in aqueous and liposome media.
The interactions between dietary fiber (DF)-bound antioxidants and free antioxidants, with different substitution patterns of -OH and -OCH3 groups on their aromatic rings has been investigated. The activity and efficiency of these interactions were examined with a structural approach. Whole wheat (WW) DF-bound antioxidants and 21 hydroxycinnamic acid/hydroxybenzoic acids (HCA/HBA) were used in the experimental studies. Studies were performed in liposome and aqueous media by monitoring lipid oxidation and scavenging of DPPH radical in the presence of WW-bound antioxidants and HCA/HBA derivatives. Predominantly synergistic interactions were observed in aqueous medium, while both synergistic and antagonistic interactions were seen in liposome medium. Concentrations of HCA/HBA and WW-bound antioxidants in mixtures and their 2-way interactions made significant effect on lipid oxidation and radical scavenging reactions, with some exceptions. HCA/HBA derivatives with 3 ,4 -dihydroxyphenyl substitution acted as strong antioxidants in liposome medium, while the number of -OH groups affected antioxidant activity in aqueous medium.
['Çelik|Ecem Evrim|EE|', 'Rubio|Jose Manuel Amigo|JMA|', 'Andersen|Mogens Larsen|ML|', 'Gökmen|Vural|V|']
D000975:Antioxidants D001713:Biphenyl Compounds D003373:Coumaric Acids D004043:Dietary Fiber D016166:Free Radical Scavengers D062385:Hydroxybenzoates D008081:Liposomes D010084:Oxidation-Reduction D010851:Picrates D013329:Structure-Activity Relationship D014908:Triticum D014867:Water D000067348:Whole Grains
Bound antioxidants Hydroxybenzoic acids Liposomes Hydroxycinnamic acids DPPH Cereal fibers