Molecular epidemiology of Pseudomonas aeruginosa in an unsegregated bronchiectasis cohort sharing hospital facilities with a cystic fibrosis cohort.
While Pseudomonas aeruginosa (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.
['Mitchelmore|Philip J|PJ|http://orcid.org/0000-0002-7850-3068', 'Randall|Joanna|J|', 'Bull|Matthew J|MJ|', 'Moore|Karen A|KA|', "O'Neill|Paul A|PA|", 'Paszkiewicz|Konrad|K|', 'Mahenthiralingam|Eshwar|E|', 'Scotton|Chris J|CJ|', 'Sheldon|Christopher D|CD|', 'Withers|Nicholas J|NJ|', 'Brown|Alan R|AR|']
bronchiectasis cystic Fibrosis bacterial infection infection control respiratory infection