Brain transcriptomics of nonhuman primates: A review.
The brain is one of the most important and intricate organs in our bodies. Interpreting brain function and illustrating the changes and molecular mechanisms during physiological or pathological processes are essential but sometimes difficult to achieve. In addition to histology, ethology and pharmacology, the development of transcriptomics alleviates this condition by enabling high-throughput observation of the brain at various levels of anatomical specificity. Moreover, because human brain samples are scarce, the brains of nonhuman primates are important alternative models. Here in this review, we summarize the applications of transcriptomics in nonhuman primate brain studies, including investigations of brain development, aging, toxic effects and diseases. Overall, as a powerful tool with developmental potential, transcriptomics has been widely utilized in neuroscience.
['Pei|Wendi|W|', 'Fu|Lin|L|', 'Li|Shui-Qing|SQ|', 'Yu|Yang|Y|']
D000375:Aging D000818:Animals D001921:Brain D001927:Brain Diseases D004195:Disease Models, Animal D000431:Ethanol D006801:Humans D008694:Methamphetamine D009488:Neurosciences D011323:Primates D000081246:RNA-Seq D000077149:Sevoflurane D059467:Transcriptome D014635:Valproic Acid
Brain Transcriptomics Nonhuman primate RNA sequencing