Chemical Composition and Allelopathic, Antibacterial, Antifungal, and Antiacetylcholinesterase Activity of Fish-mint (Houttuynia cordataThunb.) from India.
Fish-mint (Houttuynia cordataThunb.), belonging to family Saururaceae, has long been used as food and traditional herbal medicine. The present study was framed to assess the changes occurring in the essential-oil composition of H. cordata during annual growth and to evaluate allelopathic, antibacterial, antifungal, and antiacetylcholinesterase activities. The essential-oil content ranged from 0.06 - 0.14% and 0.08 - 0.16% in aerial parts and underground stem, respectively. The essential oils were analysed by GC-FID, GC/MS, and NMR (1 H and 13 C). Major constituents of aerial-parts oil was 2-undecanone (19.4 - 56.3%), myrcene (2.6 - 44.3%), ethyl decanoate (0.0 - 10.6%), ethyl dodecanoate (1.1 - 8.6%), 2-tridecanone (0.5 - 8.3%), and decanal (1.1 - 6.9%). However, major constituents of underground-stem oil were 2-undecanone (29.5 - 42.3%), myrcene (14.4 - 20.8%), sabinene (6.0 - 11.1%), 2-tridecanone (1.8 - 10.5%), β-pinene (5.3 - 10.0%), and ethyl dodecanoate (0.8 - 7.3%). Cluster analysis revealed that essential-oil composition varied substantially due to the plant parts and season of collection. The oils exhibited significant allelopathic (inhibition: 77.8 - 88.8%; LD50 : 2.45 - 3.05 μl/plate), antibacterial (MIC: 0.52 - 2.08 μl/ml; MBC: bacteriostatic) and antifungal (MIC: 2.08 - 33.33 μl/ml; MFC: 4.16 - 33.33 μl/ml) activities. The results indicate that the essential oil from H. cordata has a significant potential to allow future exploration and exploitation as a natural antimicrobial and allelopathic agent.
['Verma|Ram S|RS|', 'Joshi|Neeta|N|', 'Padalia|Rajendra C|RC|', 'Singh|Ved R|VR|', 'Goswami|Prakash|P|', 'Kumar|Ajay|A|', 'Iqbal|Hina|H|', 'Verma|Rajesh K|RK|', 'Chanda|Debabrata|D|', 'Chauhan|Amit|A|', 'Saikia|Dharmendra|D|']
D000110:Acetylcholinesterase D064089:Allelopathy D000818:Animals D000900:Anti-Bacterial Agents D000935:Antifungal Agents D001419:Bacteria D002800:Cholinesterase Inhibitors D004305:Dose-Response Relationship, Drug D005658:Fungi D052859:Houttuynia D007194:India D008826:Microbial Sensitivity Tests D009822:Oils, Volatile D018514:Plant Structures D013329:Structure-Activity Relationship
Essential-oil composition Plant parts Season Houttuynia cordata Antimicrobial activity Phytotoxic activity