Prospective memory in bipolar disorder: A meta-analysis.
There are conflicting findings about prospective memory (PM) performance in bipolar disorder. This meta-analysis systematically examined PM in patients with bipolar disorders. Articles were systematically searched in both English and Chinese databases, from their inception to Nov 15, 2016. Only case-control studies on PM in bipolar patients were included for analyses. The random effect model was used in all meta-analytic outcomes. Four studies (n = 390) comparing PM performance between patients with bipolar disorder (n = 208) and healthy controls (n = 182) were included. Three studies were rated as "high quality", while the quality of evidence in 3 meta-analyzable outcomes ranged from "moderate" (67%) to "high" (33%). Compared to healthy controls, bipolar disorder patients showed impairments in overall PM [2 studies, n = 196; SMD: - 1.08 (95%CI: - 1.61, - 0.55), P < 0.0001; I2 = 65%], event-based PM [4 studies, n = 367; SMD: - 0.51 (95%CI: - 0.78, - 0.23), P = 0.0003; I2 = 37%] and time-based PM performance [4 studies, n = 367; SMD: - 0.82 (95%CI: - 1.11, - 0.52), P < 0.0001; I2 = 41%]. In this meta-analysis, both time-based PM and event-based PM deficits appeared to be evident in bipolar disorder.
['Zhou|Fu-Chun|FC|', 'Wang|Yuan-Yuan|YY|', 'Zheng|Wei|W|', 'Ungvari|Gabor S|GS|', 'Ng|Chee H|CH|', 'Yuan|Zhen|Z|', 'Xiang|Yu-Tao|YT|']
D001714:Bipolar Disorder D016022:Case-Control Studies D005260:Female D006801:Humans D008297:Male D008569:Memory Disorders D061212:Memory, Episodic
Prospective memory Bipolar disorder Meta-analysis