Treatment of radiation-induced hemorrhagic gastritis with prednisolone: a case report.
Radiation-induced gastritis is an infrequent cause of gastrointestinal bleeding. It is a serious complication arising from radiation therapy, and the standard treatment method has not been established. The initial injury is characteristically acute inflammation of gastric mucosa. We presented a 46-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for metastatic retroperitoneal lymph node of hepatocellular carcinoma. The endoscopic examination showed diffuse edematous hyperemicmucosa with telangiectasias in the whole muscosa of the stomach and duodenal bulb. Multiple hemorrhagic patches with active oozing were found over the antrum. Anti-secretary therapy was initiated for hemostasis, but melena still occurred off and on. Finally, he was successfully treated by prednisolone therapy. We therefore strongly argue in favor of perdnisolone therapy to effectively treat patients with radiation-induced hemorrhagic gastritis.
['Zhang|Lan|L|', 'Xie|Xiao-Ying|XY|', 'Wang|Yan|Y|', 'Wang|Yan-Hong|YH|', 'Chen|Yi|Y|', 'Ren|Zheng-Gang|ZG|']
D006528:Carcinoma, Hepatocellular D004724:Endoscopy D005756:Gastritis D006471:Gastrointestinal Hemorrhage D006487:Hemostasis D006801:Humans D008113:Liver Neoplasms D016031:Liver Transplantation D008297:Male D008875:Middle Aged D009362:Neoplasm Metastasis D011239:Prednisolone D011832:Radiation Injuries D020123:Sirolimus
Hemorrhagic gastritis Prednisolone Gastrointestinal bleeding Radiation Hepatocellular carcinoma