Stereological analysis of terminal villi, intervillous space and fibrinoid of adolescent placentas and birth weight of newborns.
Aim To determine stereological structural parameters of the parenchymal part of the placenta, placental weight and volume of adolescent pregnant women and their correlation with newborns' birth weight. Methods This prospective study was conducted on a total of 60 human placentas of term pregnancy, divided into two groups according to the age of pregnant women. Experimental group consisted of 30 placentas of pregnant women aged 13-19 years. Control group consisted of 30 placentas of pregnant women aged 20-35 years. Stereological analysis was performed. Results Volumetric density of terminal villi of adolescent placentas was significantly higher than the one of control group (p <0.0001). The volumetric density of fibrinoid of adolescent placentas was significantly lower than of the control group (p <0.0001). Total volume of terminal villi of adolescent placentas was significantly higher than of the control group (p<0.0001). The total volume of fibrinoid of adolescent placentas was significantly lower than of the control group (p<0.0001). Newborns of adolescent pregnancies had in average lower birth weight of 439.01 g compared to the newborns of the control group (p <0.00001). Conclusion Adolescent pregnancy affects placental structure, weight and volume. Newborns of adolescent pregnancy have optimal body weight.
['Marković|Sergije|S|', 'Cerovac|Anis|A|', 'Kunosić|Suad|S|', 'Ramić|Suada|S|', 'Bećirović|Emir|E|']
D000293:Adolescent D001724:Birth Weight D002824:Chorionic Villi D005260:Female D006801:Humans D007231:Infant, Newborn D007413:Intestinal Mucosa D010920:Placenta D011247:Pregnancy D011446:Prospective Studies
adolescent pregnancy histological techniques maternal-fetal exchange