Solitary castrate-resistant prostate cancer metastasis to adrenal gland with concordant intense avidity on PSMA and FDG PET.
Isolated prostate cancer metastasis to the adrenal gland is rare. We report a case of concordant high uptake in a solitary adrenal metastasis on both prostate-specific membrane antigen and fluorodeoxyglucose positron-emission tomography in a patient with castrate-resistant prostate cancer. Good initial biochemical response was achieved with laparoscopic adrenalectomy. The patient developed lymph node recurrence 12 months later, although remains asymptomatic on hormonal treatment 22 months post-operatively, in keeping with prior results for metastasis-directed therapy which can delay time to additional treatment. Application of dual tracer PET can be valuable for prostate cancer staging and guidance of metastasis-directed treatment.
['McGeorge|Stephen|S|', 'Phillips|Reece|R|', 'Rukin|Nicholas J|NJ|', 'Reynolds|Jamie|J|', 'Roberts|Matthew J|MJ|']
Prostate cancer PSMA FDG Fluorodeoxyglucose Adrenalectomy Prostate specific membrane antigen