Obesity and inflammation.
The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the development of these pathologies. A better understanding of the underlying mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or prophylactic strategies. This review is aimed to present the current knowledge of adipose tissue inflammation associated with obesity.
['Karczewski|Jacek|J|', 'Śledzińska|Ewelina|E|', 'Baturo|Alina|A|', 'Jończyk|Izabela|I|', 'Maleszko|Aleksander|A|', 'Samborski|Paweł|P|', 'Begier-Krasińska|Beata|B|', 'Dobrowolska|Agnieszka|A|']
D000273:Adipose Tissue D000818:Animals D001249:Asthma D002318:Cardiovascular Diseases D003924:Diabetes Mellitus, Type 2 D006801:Humans D007249:Inflammation D009369:Neoplasms D019636:Neurodegenerative Diseases D065626:Non-alcoholic Fatty Liver Disease D009765:Obesity
obesity inflammation adipose tissue insulin resistance