Light wine consumption is associated with a lower odd for cardiovascular disease in chronic kidney disease.
AIMS
To examine the association between wine consumption and the prevalence of chronic kidney disease (CKD) and cardiovascular disease (CVD).


DATA SYNTHESIS
We performed a cross-sectional logistic regression analysis of National Health and Nutrition Examination Survey (NHANES) in participants 21 years of age or older from 2003 to 2006 in a large representative study of the U.S.


POPULATION
Wine consumption was categorized as none (0 glass per day), light (<1 glass per day), or moderate (≥1 glasses per day). Prevalent CKD was defined as a urine albumin/creatinine ratio (UACR) ≥30 mg/g or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. CVD was defined as history of CVD including angina, myocardial infarction, or stroke. Only 27 (0.5%) individuals reported moderate wine consumption, whereas 57.5% and 42% reported abstinence and light wine consumption, respectively. Light wine consumption was associated with a lower prevalence of CKD as opposed to abstinence in unadjusted analysis. After adjusting for demographics and CVD risk factors light wine consumption was associated with lower prevalence of CKD defined as UACR ≥30 mg/g but not with low eGFR. Furthermore, light wine consumption was associated with significantly lower rates of CVD in the general population and in subjects with CKD. The adjusted odd of CVD for those with light wine consumption was 0.72 (CI 0.52-0.99, p = 0.046) for the subjects with CKD.


CONCLUSION
These data suggest that light wine consumption (compared to abstinence) is associated with lower prevalence of CKD and a lower odd of CVD in those with CKD in the U.S.


POPULATION
['Jespersen|T|T|', 'Kruse|N|N|', 'Mehta|T|T|', 'Kuwabara|M|M|', 'Noureddine|L|L|', 'Jalal|D|D|']
D000328:Adult D000419:Albuminuria D064829:Alcohol Abstinence D000428:Alcohol Drinking D002318:Cardiovascular Diseases D003430:Cross-Sectional Studies D005260:Female D005919:Glomerular Filtration Rate D006801:Humans D007668:Kidney D008297:Male D008875:Middle Aged D009749:Nutrition Surveys D015995:Prevalence D011379:Prognosis D065840:Protective Factors D051436:Renal Insufficiency, Chronic D018570:Risk Assessment D012307:Risk Factors D013997:Time Factors D014481:United States D014920:Wine D055815:Young Adult
Wine consumption CKD CVD