Idiopathic granulomatous interstitial nephritis responsive to mycophenolate mofetil therapy.
Granulomatous interstitial nephritis (GIN) is a rare histologic disease. Various causes have been reported in the literature, including drugs, sarcoidosis, and infections. Other incidents have no discernible cause and are identified as idiopathic. We report a 68-year-old white man who presented with acute kidney injury and was given a diagnosis of idiopathic GIN. Mycophenolate mofetil treatment was elected because of steroid toxicity. He responded well to mycophenolate mofetil and has been in remission for more than 3 years. To our knowledge, this is the first report of successful treatment with mycophenolate mofetil of an adult patient with idiopathic GIN.
['Leeaphorn|Napat|N|', 'Stokes|Michael B|MB|', 'Ungprasert|Patompong|P|', 'Lecates|William|W|']
D058186:Acute Kidney Injury D000368:Aged D000894:Anti-Inflammatory Agents, Non-Steroidal D003404:Creatinine D005938:Glucocorticoids D006099:Granuloma D006801:Humans D007668:Kidney D008297:Male D008775:Methylprednisolone D009173:Mycophenolic Acid D009395:Nephritis, Interstitial D012074:Remission Induction D017211:Treatment Failure
mycophenolate mofetil Granulomatous interstitial nephritis (GIN)