Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop.
The incidence of metabolic and chronic diseases including cancer, obesity, inflammation-related diseases sharply increased in the 21st century. Major underlying causes for these diseases are inflammation and oxidative stress. Accordingly, natural products and their bioactive components are obvious therapeutic agents for these diseases, given their antioxidant and anti-inflammatory properties. Research in this area has been significantly expanded to include chemical identification of these compounds using advanced analytical techniques, determining their mechanism of action, food fortification and supplement development, and enhancing their bioavailability and bioactivity using nanotechnology. These timely topics were discussed at the 20th Frontier Scientists Workshop sponsored by the Korean Academy of Science and Technology, held at the University of Hawaii at Manoa on 23 November 2019. Scientists from South Korea and the U.S. shared their recent research under the overarching theme of Bioactive Compounds, Nanoparticles, and Disease Prevention. This review summarizes presentations at the workshop to provide current knowledge of the role of natural products in the prevention and treatment of metabolic diseases.
['Baek|Seung J|SJ|0000-0001-7866-7778', 'Hammock|Bruce D|BD|0000-0003-1408-8317', 'Hwang|In-Koo|IK|0000-0002-0533-4638', 'Li|Qingxiao|Q|0000-0003-4589-2869', 'Moustaid-Moussa|Naima|N|0000-0002-7508-8030', 'Park|Yeonhwa|Y|0000-0001-9727-0899', 'Safe|Stephen|S|', 'Suh|Nanjoo|N|', 'Yi|Sun-Shin|SS|', 'Zeldin|Darryl C|DC|', 'Zhong|Qixin|Q|', 'Bradbury|Jennifer Alyce|JA|', 'Edin|Matthew L|ML|', 'Graves|Joan P|JP|', 'Jung|Hyo-Young|HY|0000-0001-5725-6574', 'Jung|Young-Hyun|YH|', 'Kim|Mi-Bo|MB|', 'Kim|Woosuk|W|', 'Lee|Jaehak|J|0000-0002-3362-320X', 'Li|Hong|H|', 'Moon|Jong-Seok|JS|0000-0002-2537-7854', 'Yoo|Ik-Dong|ID|0000-0002-9966-2375', 'Yue|Yiren|Y|', 'Lee|Ji-Young|JY|', 'Han|Ho-Jae|HJ|']
D000818:Animals D000893:Anti-Inflammatory Agents D000975:Antioxidants D001688:Biological Products D019587:Dietary Supplements D006801:Humans D008659:Metabolic Diseases D051379:Mice D053758:Nanoparticles D009765:Obesity D018384:Oxidative Stress D051381:Rats
natural products cancer obesity inflammation-related diseases antioxidants nanoparticles aging anti-inflammation bioactive food components