Management of locoregional recurrence in cutaneous squamous cell carcinoma of the head and neck.
Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.
['Strassen|Ulrich|U|', 'Hofauer|Benedikt|B|', 'Jacobi|Christian|C|', 'Knopf|Andreas|A|']
D000368:Aged D000369:Aged, 80 and over D002294:Carcinoma, Squamous Cell D005260:Female D006258:Head and Neck Neoplasms D006801:Humans D008297:Male D009364:Neoplasm Recurrence, Local D018714:Radiotherapy, Adjuvant D012189:Retrospective Studies D012878:Skin Neoplasms D000077195:Squamous Cell Carcinoma of Head and Neck D016896:Treatment Outcome
Recurrence Cutaneous squamous cell carcinoma Head and neck Therapy Outcome