One new piperazinedione isolated from a mangrove-derived fungus Aspergillus niger JX-5.
One new piperazinedione derivative, nigerpiperazine A (1), along with six known compounds (2-7) were isolated from the fungus Aspergillus niger JX-5 from mangrove Ceriops tagal. Nigerpiperazine A (1) was elucidated by spectroscopic analyses and 13C NMR chemical shift calculations, compounds 4 and 5 were determined by X-ray and the CD spectra. The absolute configuration of 4 was identified by X-ray for the first time. Compounds 1 and 4 showed inhibitory activities against Helicoverpa armigera Hubner with the IC50 values of 200 and 100 µg/mL, respectively.
['Bai|Meng|M|', 'Wang|Yue|Y|', 'Liu|Ting|T|', 'Lian|Yu-Xing|YX|', 'Bai|Qi-Qi|QQ|', 'Song|Xiao-Ping|XP|', 'Han|Chang-Ri|CR|', 'Zheng|Cai-Juan|CJ|', 'Chen|Guang-Ying|GY|']
piperazinedione Aspergillus niger insecticidal activity pyrone derivatives