Persistent Legionnaire's disease in an adult with hairy cell leukemia successfully treated with prolonged levofloxacin therapy.
Legionnaire's disease (LD) manifests most commonly as an atypical community acquired pneumonia (CAP) with systemic extrapulmonary manifestations. Disorders associated with impaired cell mediated immunity (CMI) are particularly predisposed to LD. Hairy cell leukemia (HCL) is a rare B-cell lymphoproliferative leukemia associated with decreased CMI. LD has only rarely been reported in HCL. We present a most interesting case of persistent LD in a elderly male with HCL who required prolonged antibiotic therapy.
['Cunha|Burke A|BA|', 'Munoz-Gomez|Sigridh|S|', 'Gran|Arthur|A|', 'Raza|Muhammad|M|', 'Irshad|Nadia|N|']
D000368:Aged D000900:Anti-Bacterial Agents D002908:Chronic Disease D017714:Community-Acquired Infections D006801:Humans D007877:Legionnaires' Disease D007943:Leukemia, Hairy Cell D064704:Levofloxacin D008297:Male D018410:Pneumonia, Bacterial D016896:Treatment Outcome
Clinical diagnosis of Legionnaire's disease Legionnaire's disease atypical pneumonia Legionnaire's disease in compromised hosts Legionnaire's disease therapy Oral antibiotic therapy