Primary Cutaneous Mucormycosis Caused by Rhizopus oryzae: A Case Report and Review of Literature.
Mucormycosis is an invasive infection caused by opportunistic fungi. Rhizopus, Lichtheimia, Mucor and Rhizomucor are the most common isolated genera. Primary cutaneous mucormycosis is usually related to traumatic injuries, but immunocompromised cases are associated with underlying conditions such as diabetes mellitus and malignancies. The treatment of choice is surgical debridement and liposomal amphotericin B. We present a 40-year-old male with fever and a painful necrotic lesion on the middle back and history of poorly controlled diabetes mellitus. Rhizopus oryzae was isolated and identified using an internal transcribed spacer regions ITS1 and ITS2. An initial good response to treatment was observed; however, 7 days later a diabetic ketoacidosis due to poor adherence to treatment caused a lethal outcome.
['Rodríguez-Lobato|Erika|E|', 'Ramírez-Hobak|Lourdes|L|', 'Aquino-Matus|Jorge E|JE|', 'Ramírez-Hinojosa|Juan P|JP|', 'Lozano-Fernández|Víctor H|VH|', 'Xicohtencatl-Cortes|Juan|J|', 'Hernández-Castro|Rigoberto|R|', 'Arenas|Roberto|R|']
D000328:Adult D004271:DNA, Fungal D021903:DNA, Ribosomal Spacer D003881:Dermatomycoses D048909:Diabetes Complications D006651:Histocytochemistry D006801:Humans D008297:Male D008853:Microscopy D009091:Mucormycosis D012233:Rhizopus D017422:Sequence Analysis, DNA D012867:Skin
Primary cutaneous mucormycosis Rhizopus oryzae Opportunistic fungal infection