Clinical and quality-of-life outcomes following gland-preserving surgery for chronic sialadenitis.
OBJECTIVES/HYPOTHESIS
Gland-preserving salivary surgery utilizing salivary endoscopy has been proposed as a treatment alternative in the management of chronic sialadenitis. This study seeks to determine medium-term clinical and quality-of-life (QOL) outcomes following a gland-preserving approach for chronic sialadenitis.


STUDY DESIGN
Cross-sectional survey with retrospective chart review.


METHODS
All patients undergoing attempted gland-preserving salivary surgery with salivary endoscopy for chronic sialadenitis at a tertiary, academic salivary referral center between October 2008 and April 2013 were identified from a quality assurance database. A research database was constructed to examine clinical factors of interest. A clinical outcomes and QOL survey was mailed to all eligible patients in order to obtain long-term follow-up data.


RESULTS
A total of 206 of 306 (67%) eligible patients returned the survey. The median length of follow-up was 17 months (3-54 months). The majority of patients (89%) endorsed symptom improvement after gland-preserving therapy. Surgical excision was performed on 8% of affected glands. Patients with chronic sialadenitis due to stones reported a greater incidence of symptom resolution (P = 0.0004) and more favorable QOL outcomes (P = 0.0001) than patients with nonstone etiologies.


CONCLUSIONS
Patients undergoing gland-preserving salivary surgery with salivary endoscopy for chronic sialadenitis have favorable long-term symptom improvement and gland retention rates. Although patients with stones demonstrated the best outcomes, improvement was documented for all etiologies of chronic sialadenitis.


LEVEL OF EVIDENCE
4.
['Gillespie|M Boyd|MB|', "O'Connell|Brendan P|BP|", 'Rawl|Jordan W|JW|', 'McLaughlin|Conor W|CW|', 'Carroll|William W|WW|', 'Nguyen|Shaun A|SA|']
D000293:Adolescent D000328:Adult D000368:Aged D000369:Aged, 80 and over D002648:Child D002675:Child, Preschool D003430:Cross-Sectional Studies D004724:Endoscopy D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D059351:Organ Sparing Treatments D011788:Quality of Life D012189:Retrospective Studies D012469:Salivary Glands D012793:Sialadenitis D016896:Treatment Outcome D055815:Young Adult
chronic sialadenitis Sialadenitis salivary endoscopy quality of life salivary stone sialendoscopy sialolithiasis