Three new alkaloids and three new phenolic glycosides from Liparis odorata.
Three new alkaloids, liparis alkaloid A (1), B (2), C (3), and three new phenolic glycosides, liparis glycoside H (4), I (5), J (6), together with three known phenolic glycosides (7-9) were isolated from the whole plant of Liparis odorata. Their structures were characterized on the basis of extensive 1D-, 2D-NMR and HR-ESI-MS experiments. In addition, compounds 1-3 revealed hypolipidemic effects in the in vitro bioassays, and the ability to inhibit LPS-induced NO production of these isolated phenolic glycosides (4-9) was also evaluated.
['Jiang|Piao|P|', 'Liu|Hongdong|H|', 'Xu|Xianghong|X|', 'Liu|Bo|B|', 'Zhang|Dongming|D|', 'Lai|Xuewen|X|', 'Zhu|Genghua|G|', 'Xu|Peng|P|', 'Li|Bin|B|']
D000470:Alkaloids D000818:Animals D002460:Cell Line D006027:Glycosides D056945:Hep G2 Cells D006801:Humans D000960:Hypolipidemic Agents D009682:Magnetic Resonance Spectroscopy D013058:Mass Spectrometry D051379:Mice D017628:Microglia D015394:Molecular Structure D009569:Nitric Oxide D029595:Orchidaceae D010636:Phenols
Alkaloids Phenolic glycosides Liparis odorata Hypolipidemic effect NO production inhibitory activities Orchid family