Determinants of disability using count-based approaches to ICF-based definition of neurological disability.
INTRODUCTION
The aim of this study was to explore the most relevant determinants of severe disability in a heterogeneous sample of patients with neurological conditions.


OBJECTIVES
We used data from previous studies on patients with myasthenia gravis (MG), migraine, Parkinson's disease (PD), multiple sclerosis, traumatic brain injury (TBI), stroke and epilepsy (349 patients, aged 18-74 years; mean 48.0, SD 11.7). We calculated count-based extension indexes to address severe disability, and hierarchical logistic regression to assess the association between severe disability, sociodemographic and health status information.


CONCLUSIONS
Results show that sociodemographic variables played a minor role, while health state information was a stronger determinant of severe disability. Compared to the reference value of TBI patients, those with MG, PD and epilepsy had higher odds to have severe difficulties undertaking daily activities despite the presence of environmental factors. Our results contrast with those of previous studies, mostly derived from general populations, showing the different impact of clinical and sociodemographic variables.
['Raggi|A|A|', 'Covelli|V|V|', 'Leonardi|M|M|', 'Meucci|P|P|', 'Scaratti|C|C|', 'Schiavolin|S|S|', 'Willems|M|M|', 'Sattin|D|D|']
D000203:Activities of Daily Living D000293:Adolescent D000328:Adult D000368:Aged D003430:Cross-Sectional Studies D004185:Disability Evaluation D005260:Female D006801:Humans D064702:International Classification of Functioning, Disability and Health D008297:Male D008875:Middle Aged D009422:Nervous System Diseases D055815:Young Adult
Disability ICF classification barriers mental functions mobility