The correlation between thyrotropin and dyslipidemia in a population-based study.
This study investigated the relationship between serum thyrotrophin levels and dyslipidemia in subclinical hypothyroid and euthyroid subjects. A total of 110 subjects with subclinical hypothyroidism and 1,240 euthyroid subjects enrolled in this study. Patients with subclinical hypothyroidism had significantly lower high density lipoprotein cholesterol (HDL-C) levels than those who were euthyroid. The lipid profiles were each categorized and mean thyrotrophin levels were higher in subjects in the dyslipidemia subclasses than subjects in the normal subclasses. Thyrotrophin was positively associated with serum triglyceride and negatively associated with serum HDL-C in women. Thyrotrophin was also positively associated with total cholesterol (TC) in the overweight population along with TC and LDL-C in overweight women. In the euthyroid population, thyrotrophin was positively associated with TC in the overweight population. In conclusion, serum thyrotrophin was correlated with dyslipidemia in subclinical hypothyroid and euthyroid subjects; the correlation was independent of insulin sensitivity.
['Lu|Li|L|', 'Wang|Beibei|B|', 'Shan|Zhongyan|Z|', 'Jiang|Fengwei|F|', 'Teng|Xiaochun|X|', 'Chen|Yanyan|Y|', 'Lai|Yaxin|Y|', 'Wang|Jiani|J|', 'Xue|Haibo|H|', 'Wang|Sen|S|', 'Li|Chenyan|C|', 'Liu|He|H|', 'Li|Ningna|N|', 'Yu|Jiashu|J|', 'Shi|Liangfeng|L|', 'Hou|Xin|X|', 'Xing|Qian|Q|', 'Bai|Xue|X|', 'Teng|Weiping|W|']
D000293:Adolescent D000328:Adult D000368:Aged D000369:Aged, 80 and over D002784:Cholesterol D008076:Cholesterol, HDL D050171:Dyslipidemias D005260:Female D006801:Humans D007333:Insulin Resistance D008055:Lipids D008297:Male D008875:Middle Aged D013972:Thyrotropin D014280:Triglycerides D055815:Young Adult
Thyrotropin Triglyceride Total Cholesterol Cholesterol, HDL Cholesterol, LDL