Colonic biogeography in health and ulcerative colitis.
The relevance of biogeography to the distal gut microbiota has been investigated in both health and inflammatory bowel disease (IBD), however multiple factors, including sample type and methodology, microbiota characterization and interpersonal variability make the construction of a core model of colonic biogeography challenging. In addition, how phylogenetic classification relates to immunogenicity and whether consistent alterations in the microbiota are associated with ulcerative colitis (UC) remain open questions. This addendum seeks to review the human colonic microbiota in health and UC as currently understood, in the broader context of the human microbiome.
['Lavelle|Aonghus|A|', 'Lennon|Grainne|G|', 'Winter|Desmond C|DC|', "O'Connell|P Ronan|PR|"]
D000818:Animals D001419:Bacteria D003093:Colitis, Ulcerative D003106:Colon D000069196:Gastrointestinal Microbiome D006262:Health D006801:Humans D010802:Phylogeny
Biogeography ulcerative colitis microbiota inflammatory bowel disease microbiome spatial ecology