A pediatric case of T-cell prolymphocytic leukemia.
T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.
['Mitton|Bryan|B|', 'Coutre|Steven|S|', 'Willert|Jennifer|J|', 'Schlis|Krysta|K|', 'Porteus|Matthew|M|', 'Kharbanda|Sandhya|S|', 'Agarwal-Hashmi|Rajni|R|']
D000293:Adolescent D018380:Hematopoietic Stem Cell Transplantation D006801:Humans D015461:Leukemia, Prolymphocytic, T-Cell D008297:Male D014184:Transplantation, Homologous
pediatrics T-cell prolymphocytic leukemia bone marrow transplant