Rhodium(III)-catalyzed three-component reaction of imines, alkynes, and aldehydes through C-H activation.
An efficient rhodium(III)-catalyzed tandem three-component reaction of imines, alkynes and aldehydes through CH activation has been developed. High stereo- and regioselectivity, as well as good yields were obtained in most cases. The simple and atom-economical approach offers a broad scope of substrates, providing polycyclic skeletons with potential biological properties.
['Huang|Ji-Rong|JR|', 'Song|Qiang|Q|', 'Zhu|Yu-Qin|YQ|', 'Qin|Liu|L|', 'Qian|Zhi-Yong|ZY|', 'Dong|Lin|L|']
D000447:Aldehydes D000480:Alkynes D002384:Catalysis D007097:Imines D015394:Molecular Structure D011083:Polycyclic Compounds D012238:Rhodium
CH activation cyclization multicomponent reactions rhodium