A rare case report of malignant peripheral nerve sheath tumor involving both the small bowel and large bowel.
Malignant peripheral nerve sheath tumor (MPNST) contains properties and histologic markers of both neural crest cells and mesenchymal cells. It is a rare diagnosis, with an incidence of 1:100,000/year or 4%-10% of soft-tissue sarcomas. There are very few cases reported and studied. Therefore, establishing a proper diagnosis and treatment of MPNST provides a challenge. We present this unique and rare case of metastatic MPNST of the small and large bowel with bone, pulmonary, liver, and splenic metastases. The patient subsequently developed hemorrhagic brain metastases and died 6 months after THE initial diagnosis.
['Khan|Nazia|N|', 'Hashmi|Irma|I|', 'Atallah|Liana|L|', 'Shaaban|Hamid|H|', 'Guron|Gunwant|G|', 'Fedida|Andre|A|']
D000368:Aged D000903:Antibiotics, Antineoplastic D001859:Bone Neoplasms D017024:Chemotherapy, Adjuvant D004317:Doxorubicin D006801:Humans D007414:Intestinal Neoplasms D007420:Intestine, Large D007421:Intestine, Small D008297:Male D009362:Neoplasm Metastasis D016609:Neoplasms, Second Primary D018317:Nerve Sheath Neoplasms D018319:Neurofibrosarcoma D012983:Soft Tissue Neoplasms D016896:Treatment Outcome
Malignant peripheral nerve sheath tumor metastatic small and large bowel