Analysis of Radiation Effects in Digital Subtraction Angiography of Intracranial Artery Stenosis.
BACKGROUND
Intracranial artery stenosis (IAS) is the most common cause for acute cerebral accidents. Digital subtraction angiography (DSA) is the gold standard to detect IAS and usually brings excess radiation exposure to examinees and examiners. The artery pathology might influence the interventional procedure, causing prolonged radiation effects. However, no studies on the association between IAS pathology and operational parameters are available.


METHODS
A retrospective analysis was conducted on 93 patients with first-ever stroke/transient ischemic attack, who received DSA examination within 3 months from onset in this single center. Comparison of baseline characteristics was determined by 2-tailed Student's t-test or the chi-square test between subjects with and without IAS. A binary logistic regression analysis was performed to determine the association between IAS pathology and the items with a P value <0.05 in Student's t-test or chi-square test.


RESULTS
There were 93 candidates (42 with IAS and 51 without IAS) in this study. The 2 groups shared no significance of the baseline characteristics (P > 0.05). We found a significantly higher total time, higher kerma area product, greater total dose, and greater DSA dose in the IAS group than in those without IAS (P < 0.05). A binary logistic regression analysis indicated the significant association between total time and IAS pathology (P < 0.05) but no significance in kerma area product, radiation dose, and DSA dose (P > 0.05).


CONCLUSIONS
IAS pathology would indicate a prolonged total time of DSA procedure in clinical practice. However, the radiation effects would not change with pathologic changes.
['Guo|Chaoqun|C|', 'Shi|Xiaolei|X|', 'Ding|Xianhui|X|', 'Zhou|Zhiming|Z|']
D000328:Adult D000368:Aged D015901:Angiography, Digital Subtraction D001158:Arteries D002533:Cerebral Angiography D003251:Constriction, Pathologic D005260:Female D006801:Humans D002537:Intracranial Arteriosclerosis D002546:Ischemic Attack, Transient D018810:Magnetic Resonance Angiography D008297:Male D008875:Middle Aged D000069079:Radiation Exposure D012189:Retrospective Studies D012680:Sensitivity and Specificity D014057:Tomography, X-Ray Computed
Radiation Intracranial artery stenosis Association Operation