Can local infiltration of lidocaine reduce the postoperative atrial fibrillation rate in patients undergoing lobectomy for lung cancer?
Background: Postoperative atrial fibrillation (POAF) occurs frequently after lung cancer surgery. Unfortunately, owing to the multifactorial etiology of POAF, no single drug or intervention can prevent POAF in all cases. The effects of local interventions after lung cancer surgery are unknown. This study investigated the effects of local infiltration of an anesthetic (lidocaine) on the post-lobectomy POAF rate.Methods: This non-randomized study included 81 patients who underwent lobectomy for lung cancer. Patients were divided into a lidocaine-infiltration group comprising patients who received lidocaine infiltration around the pulmonary veins and a no-intervention group. Patients were monitored for the development of POAF during hospitalization. Pre- and postoperative demographic and clinical data were analyzed.Results: AF occurred in 3 (7.5%) of 40 patients in the lidocaine-infiltration group and in 10 (24.39%) of 41 patients in the standard surgical resection group. Overall, it was observed that intraoperative lidocaine infiltration resulted in a lower POAF rate (p < .05).Conclusion: Local infiltration of lidocaine around the pulmonary veins in patients undergoing lobectomy for lung cancer was associated with a lower incidence of POAF, which is attributable to the local anesthetic and autonomic effects of lidocaine.
['Akkuş|Murat|M|http://orcid.org/0000-0002-3762-6328', 'Öner|Ender|E|']
D000368:Aged D000772:Anesthesia, Local D000779:Anesthetics, Local D001281:Atrial Fibrillation D002289:Carcinoma, Non-Small-Cell Lung D005260:Female D005500:Follow-Up Studies D006801:Humans D015994:Incidence D008012:Lidocaine D008175:Lung Neoplasms D008297:Male D011013:Pneumonectomy D011183:Postoperative Complications D012189:Retrospective Studies D012307:Risk Factors D014421:Turkey
lidocaine Atrial fibrillation lobectomy (lung) lung cancer-surgery