Surface Interactions between Bacterial Nanocellulose and B-Complex Vitamins.
The interactions between films of bacterial nanocellulose (BNC) and B complex vitamins were studied using a Quartz Crystal Microbalance with Dissipation monitoring (QCM-D). Thin films of BNC were generated in situ by QCM-D, followed by real-time measurements of the vitamin adsorption. The desorption of vitamins was induced by rinsing the system using phosphate buffers at a pH of 2 and 6.5, emulating gastric conditions. Changes in frequency (which are proportional to changes in adsorbed mass, ∆m) detected by QCM-D were used to determine the amounts of vitamin adsorbed and released from the BNC film. Additionally, changes in dissipation (∆D) were proven to be useful in identifying the effects of the pH in both pristine cellulose films and films with vitamin pre-adsorbed, following its changes during release. The effects of pH on the morphology of the vitamin-BNC surfaces were also monitored by changes in rugosity from images obtained by atomic force microscopy (AFM). Based on this data, we propose a model for the binding phenomena, with the contraction on the relaxation of the cellulose film depending on pH, resulting in an efficient vitamin delivery process.
['Sánchez-Osorno|Diego Mauricio|DM|', 'Gomez-Maldonado|Diego|D|', 'Castro|Cristina|C|0000-0002-8994-597X', 'Peresin|María Soledad|MS|']
D000327:Adsorption D002482:Cellulose D041821:Gluconacetobacter D018625:Microscopy, Atomic Force D008968:Molecular Conformation D053758:Nanoparticles D058525:Quartz Crystal Microbalance Techniques D013499:Surface Properties D014803:Vitamin B Complex
bacterial nanocellulose vitamins QCM-D adsorption release