Curcumin in tissue engineering: A traditional remedy for modern medicine.
Curcumin is the principal polyphenolic compound present in turmeric with broad applications in tissue engineering and regenerative medicine. It has some important inherent properties with the potential to facilitate tissue healing, including anti-inflammatory, anti-oxidant, and antibacterial activities. Therefore, curcumin has been used for the treatment of various damaged tissues, especially wound injuries. There are different forms of curcumin, among which nano-formulations are of a great importance in regenerative medicine. It is also important to design sophisticated delivery systems for controlled/localized delivery of curcumin to the target tissues and organs. Although there are many reports on the advantages of this compound, further research is required to fully explore its clinical usage. The review describes the physicochemical and biological properties of curcumin and the current state of the evidence on its applications in tissue engineering. © 2018 BioFactors, 45(2):135-151, 2019.
['Ahangari|Najmeh|N|', 'Kargozar|Saeid|S|', 'Ghayour-Mobarhan|Majid|M|', 'Baino|Francesco|F|', 'Pasdar|Alireza|A|', 'Sahebkar|Amirhossein|A|', 'Ferns|Gordon A A|GAA|', 'Kim|Hae-Won|HW|', 'Mozafari|Masoud|M|https://orcid.org/0000-0002-0232-352X']
D000818:Animals D000900:Anti-Bacterial Agents D000893:Anti-Inflammatory Agents D000975:Antioxidants D003474:Curcumin D006801:Humans D057927:Hydrophobic and Hydrophilic Interactions D036103:Nanotechnology D023822:Tissue Engineering D014945:Wound Healing
curcumin tissue engineering anti-oxidant antibacterial anti-inflammation scaffold tissue repair wound healing