A survey and evaluation of Web-based tools/databases for variant analysis of TCGA data.
The Cancer Genome Atlas (TCGA) is a publicly funded project that aims to catalog and discover major cancer-causing genomic alterations with the goal of creating a comprehensive 'atlas' of cancer genomic profiles. The availability of this genome-wide information provides an unprecedented opportunity to expand our knowledge of tumourigenesis. Computational analytics and mining are frequently used as effective tools for exploring this byzantine series of biological and biomedical data. However, some of the more advanced computational tools are often difficult to understand or use, thereby limiting their application by scientists who do not have a strong computational background. Hence, it is of great importance to build user-friendly interfaces that allow both computational scientists and life scientists without a computational background to gain greater biological and medical insights. To that end, this survey was designed to systematically present available Web-based tools and facilitate the use TCGA data for cancer research.
['Zhang|Zhuo|Z|', 'Li|Hao|H|', 'Jiang|Shuai|S|', 'Li|Ruijiang|R|', 'Li|Wanying|W|', 'Chen|Hebing|H|', 'Bo|Xiaochen|X|']
D014408:Biomarkers, Tumor D019295:Computational Biology D030541:Databases, Genetic D020869:Gene Expression Profiling D023281:Genomics D006801:Humans D020407:Internet D009154:Mutation D009369:Neoplasms D012984:Software D011795:Surveys and Questionnaires D016019:Survival Analysis D014584:User-Computer Interface
survey databases The Cancer Genome Atlas cancer bioinformatics tools