Does diabetes mellitus comorbidity affect in-hospital mortality and length of stay? Analysis of administrative data in an Italian Academic Hospital.
AIMS
Hospitalized patients with comorbid diabetes mellitus may have worse outcomes than the others. We conducted a study to assess whether comorbid diabetes affects in-hospital mortality and length of stay.


METHODS
For this population-based study, we analyzed the administrative databases of the Regional Health Information System of the Region Friuli Venezia Giulia, where the Hospital of Udine is located. Hospital discharge data were linked at the individual patient level with the regional Diabetes Mellitus Registry to identify diabetic patients. For each 3-digit ICD-9-CM discharge diagnosis code, we assessed the difference in length of stay and in-hospital mortality between diabetic and non-diabetic patients. We conducted both univariate and multivariate analyses, adjusted for age, sex, Charlson's comorbidity score, and urgency of hospitalization, through linear and logistic regression models.


RESULTS
After adjusting for potential confounders, diabetes significantly increased the risk of in-hospital death among patients hospitalized for bacterial pneumonia (OR = 1.94) and intestinal obstruction (OR = 4.23) and length of stay among those admitted for several diagnoses, including acute myocardial infarction and acute renal failure. Admission glucose blood level was associated with in-hospital death in patients with pneumonia and intestinal obstruction, and increased length of stay for several conditions.


CONCLUSIONS
Patients with diabetes mellitus who are hospitalized for other health problems may have increased risk of in-hospital death and longer hospital stay. For this reason, diabetes should be promptly recognized upon admission and properly managed.
['Valent|Francesca|F|http://orcid.org/0000-0002-4071-0897', 'Tonutti|Laura|L|', 'Grimaldi|Franco|F|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D001786:Blood Glucose D015897:Comorbidity D016208:Databases, Factual D003920:Diabetes Mellitus D005260:Female D017052:Hospital Mortality D006760:Hospitalization D006785:Hospitals, University D006801:Humans D007558:Italy D007674:Kidney Diseases D007902:Length of Stay D008297:Male D008875:Middle Aged D009203:Myocardial Infarction
Diabetes mellitus In-hospital mortality Length of stay Administrative data Hospitalization