Facile fabrication of novel konjac glucomannan films with antibacterial properties via microfluidic spinning strategy.
The exploration of methods to produce biomaterials with antibacterial properties in ultra-small scales is of great scientific and technological interest. Here, we reported a microfluidic spinning approach to prepare a novel film combined with konjac glucomannan (KGM), polyvinylpyrrolidone (PVP), and epigallocatechin gallate (EGCG). The film was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and thermogravimetric analysis. This film was transparent, orderly, thermally stable, and uniform in size, with an average width less than 1 μm. Also, the film exhibited excellent antibacterial efficiency (97.1% against E. coli, 99.7% against S. aureus, 97.3% against S. enterica and 99.9% against B. subtilis) in our antibacterial test. In addition, the film promoted wound healing with the advanced development of neovascularization and hair follicles. This strategy provides a facile and green pathway for the construction of biomaterial films for medical applications.
['Ni|Yongsheng|Y|', 'Lin|Wanmei|W|', 'Mu|Ruojun|R|', 'Wu|Chunhua|C|', 'Lin|Zheya|Z|', 'Chen|Su|S|', 'Pang|Jie|J|']
D000818:Animals D000900:Anti-Bacterial Agents D001458:Bandages D008297:Male D008351:Mannans D008567:Membranes, Artificial D044085:Microfluidics D008855:Microscopy, Electron, Scanning D011134:Polysaccharides D051381:Rats D017550:Spectroscopy, Fourier Transform Infrared D013818:Thermogravimetry D014945:Wound Healing D014961:X-Ray Diffraction
Konjac glucomannan Films Antibacterial properties Wound healing Microfluidic spinning technology