Bile Acid Conjugates with Anticancer Activity: Most Recent Research.
The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules.
['Navacchia|Maria Luisa|ML|0000-0001-7175-1504', 'Marchesi|Elena|E|', 'Perrone|Daniela|D|0000-0001-5189-011X']
D000818:Animals D000970:Antineoplastic Agents D001647:Bile Acids and Salts D006801:Humans D009369:Neoplasms
bile acids conjugates anticancer agents bioconjugation drug design natural product hybrids pharmacological activity