Adverse Perioperative Events in Children with Complex Congenital Heart Disease Undergoing Operative Scoliosis Repair in the Contemporary Era.
Scoliosis is common in children with congenital heart disease (CHD) and may have deleterious effects on quality of life and hemodynamics. Relatively little is known about the outcomes of spinal fusion for scoliosis repair in children with complex CHD. We reviewed all cases of children with CHD undergoing first time spinal fusion excluding those with minor CHD between 1995 and 2015. Seventy-eight patients were identified and included in the study. 97.4% of patients included had undergone prior cardiac surgery and sixteen patients had single ventricle circulations. 17.9% of patients experienced a significant perioperative event defined as an aggregate of the presence of any of the following: need for early unanticipated reoperation, neurologic deficit, postoperative bleeding requiring intervention, end organ dysfunction, or death. There were no deaths in our cohort. 38.5% of patients experienced any adverse event, the majority of which were related to perioperative fluid shifts. Larger preoperative Cobb angle and longer length of spinal fusion were associated with increased risk of significant perioperative event while larger preoperative Cobb angle and longer length of spinal fusion, older age at time of surgery, single ventricle circulation, cyanosis and patients taking cardiac medications at the time of surgery were more likely to experience any adverse event. Operative repair of scoliosis in children with complex CHD has been performed without mortality over a 20-year period in a single institution, albeit with a higher rate of perioperative complication than is seen in the general pediatric population. Patients with large preoperative Cobb angles and cyanotic single ventricle circulations appear to be at the highest risk for perioperative complications.
['Przybylski|Robert|R|http://orcid.org/0000-0001-7938-0998', 'Hedequist|Daniel J|DJ|', 'Nasr|Viviane G|VG|', 'McCann|Mary Ellen|ME|', 'Brustowicz|Robert M|RM|', 'Emans|John B|JB|', 'Marshall|Audrey C|AC|', 'Brown|David W|DW|']
D000293:Adolescent D000368:Aged D016022:Case-Control Studies D002648:Child D005260:Female D006330:Heart Defects, Congenital D006801:Humans D008297:Male D011183:Postoperative Complications D012189:Retrospective Studies D012600:Scoliosis D013123:Spinal Fusion D016896:Treatment Outcome
Congenital heart disease Scoliosis Spinal fusion