Pulmonary Involvement during the Ebola Virus Disease.
Filoviruses have become a worldwide public health concern, especially during the 2013-2016 Western Africa Ebola virus disease (EVD) outbreak-the largest outbreak, both by number of cases and geographical extension, recorded so far in medical history. EVD is associated with pathologies in several organs, including the liver, kidney, and lung. During the 2013-2016 Western Africa outbreak, Ebola virus (EBOV) was detected in the lung of infected patients suggesting a role in lung pathogenesis. However, little is known about lung pathogenesis and the controversial issue of aerosol transmission in EVD. This review highlights the pulmonary involvement in EVD, with a special focus on the new data emerging from the 2013-2016 Ebola outbreak.
['Lalle|Eleonora|E|', 'Biava|Mirella|M|', 'Nicastri|Emanuele|E|', 'Colavita|Francesca|F|0000-0003-0640-8667', 'Di Caro|Antonino|A|0000-0001-6027-3009', 'Vairo|Francesco|F|', 'Lanini|Simone|S|', 'Castilletti|Concetta|C|0000-0001-9819-236X', 'Langer|Martin|M|', 'Zumla|Alimuddin|A|0000-0002-5111-5735', 'Kobinger|Gary|G|', 'Capobianchi|Maria R|MR|', 'Ippolito|Giuseppe|G|0000-0002-1076-2979']
D000354:Africa, Western D000818:Animals D004196:Disease Outbreaks D029043:Ebolavirus D005260:Female D019142:Hemorrhagic Fever, Ebola D006801:Humans D008168:Lung D008297:Male D012141:Respiratory Tract Infections
Ebola virus Ebola virus disease lung pathogenesis respiratory disease