The kidney stone and increased water intake trial in steel workers: results from a pilot study.
Preventing dehydration in subjects at risk may provide a means of primary prevention of kidney stones. The purpose of this pilot study was to assess the hydration status of an at-risk group of steel plant workers based on end-of-shift ('post-shift') spot urine osmolality and 24-h urinary stone risk parameters. 100 volunteers were recruited from Gerdau Midlothian steel mill in Texas on 11/14/14 and 12/5/14. Clinical data were recorded and post-shift spot urine sample was used to measure urine osmolality. Participants were invited to submit a 24-h urine sample within 4 weeks of enrollment. The mean age was 41 years and 95 % were men. The majority of subjects were white (75 %), followed by 10 % Hispanic and 9 % black. The mean body mass index was 30.1 kg/m2 and overall 16 % had a past history of stone disease. Mean post-shift urine spot osmolality was 704.5 mOsm (169-1165 mOsm) and was >800 and >700 mOsm in 39 and 57 %, respectively. Among 59 24-h urines samples, the mean volume was 1.89 ± 0.92 l/day, with 56 % < 2 L and 17 % < 1 L. Elevated levels of urinary analytes were found in 29 % of subjects for calcium (>250 mg/TV), 39 % for uric acid (>700 mg/TV), 25 % for oxalate (>45 mg/TV) and 50 % for sodium (>200 meq/TV). The prevalence of stone disease in this population of steel workers was higher than the published prevalence of stone disease in the general population. A significant number of workers had concentrated post-shift and 24-h urines and elevated levels of urinary analytes.
['Lotan|Yair|Y|', 'Antonelli|Jodi|J|', 'Jiménez|Inmaculada Buendia|IB|', 'Gharbi|Hakam|H|', 'Herring|Ron|R|', 'Beaver|Allison|A|', 'Dennis|Aphrihl|A|', 'Von Merveldt|Dendra|D|', 'Carter|Suzie|S|', 'Cohen|Adam|A|', 'Poindexter|John|J|', 'Moe|Orson W|OW|', 'Pearle|Margaret S|MS|']
D000328:Adult D000368:Aged D002118:Calcium D003430:Cross-Sectional Studies D003681:Dehydration D004326:Drinking D005260:Female D006801:Humans D007669:Kidney Calculi D008297:Male D008669:Metallurgy D008875:Middle Aged D016273:Occupational Exposure D009994:Osmolar Concentration D010070:Oxalates D010865:Pilot Projects D015995:Prevalence D012307:Risk Factors D012964:Sodium D014527:Uric Acid D014556:Urine
Kidney stones Steel workers Prevention Hydration