Biomimetic particles as therapeutics.
In recent years, there have been major advances in the development of novel nanoparticle- and microparticle-based therapeutics. An emerging paradigm is the incorporation of biomimetic features into these synthetic therapeutic constructs to enable them to better interface with biological systems. Through the control of size, shape, and material consistency, particle cores have been generated that better mimic natural cells and viruses. In addition, there have been significant advances in biomimetic surface functionalization of particles through the integration of bio-inspired artificial cell membranes and naturally derived cell membranes. Biomimetic technologies enable therapeutic particles to have increased potency to benefit human health.
['Meyer|Randall A|RA|', 'Sunshine|Joel C|JC|', 'Green|Jordan J|JJ|']
D000818:Animals D040761:Biomimetic Materials D032701:Biomimetics D006801:Humans D051379:Mice D053758:Nanoparticles D036103:Nanotechnology
biomimetic biomaterial drug delivery micro/nanoparticle