New phenolic glycosides from Polygonum cuspidatum.
Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory activity of compounds 1-3 were estimated and none of them exhibited activities at a concentration of 10 μM.
['Jiang|Jian-Shuang|JS|', 'Li|Fu-Shuang|FS|', 'Feng|Zi-Ming|ZM|', 'Yang|Ya-Nan|YN|', 'Zhang|Pei-Cheng|PC|']
D045468:Fallopia japonica D006027:Glycosides D049934:Isocoumarins D015394:Molecular Structure D010636:Phenols D028502:Polygonum
Polygonum cuspidatum isobenzofuranone isocoumarin cytotoxicity activity PTP1B