Biological effects of mixed-ion beams. Part 2: The relative biological effectiveness of CHO-K1 cells irradiated by mixed- and single-ion beams.
The relative biological effectiveness (RBE) values were determined for single- and mixed-ion beams containing carbon and oxygen ions. The CHO-K1 cells were irradiated with beams with the linear energy transfer (LET) values of 236-300 and 461-470 keV/μm for 12C and 16O ions, respectively. The RBE was estimated as a function of dose, survival fraction (SF) and LET. The SF was not affected by varying contributions of the constituent ions to the total mixed dose. The RBE has the same value for single-ion exposures with ions with LET 300 (12C) and 470 keV/μm (16O).
['Czub|Joanna|J|', 'Banaś|Dariusz|D|', 'Braziewicz|Janusz|J|', 'Buraczewska|Iwona|I|', 'Jaskóła|Marian|M|', 'Kaźmierczak|Urszula|U|', 'Korman|Andrzej|A|', 'Lankoff|Anna|A|', 'Lisowska|Halina|H|', 'Szefliński|Zygmunt|Z|', 'Wojewódzka|Maria|M|', 'Wójcik|Andrzej|A|']
D000818:Animals D016466:CHO Cells D002470:Cell Survival D003412:Cricetulus D063193:Heavy Ion Radiotherapy D020450:Heavy Ions D007477:Ions D018499:Linear Energy Transfer D009369:Neoplasms D010100:Oxygen D012062:Relative Biological Effectiveness
Relative biological effectiveness CHO-K1 cells Ions beams