Novel method to evaluate the risk of tumor adhesions and post-operative hemorrhage of meningiomas using 320 row CT-DSA: A clinical research study.
OBJECTIVE
Meningioma is an extra-axial tumor that forms adhesions toward the brain surface in the course of its growth. Predicting adhesions between the tumor and the brain surface leads to better predictions of surgical results. There are few studies on brain-tumor adhesions or postoperative hemorrhage. This study aimed to assess tumor vascularity of the dura and cerebral surface, and predict surgical outcomes using four-dimensional computed tomography angiography (4D CTA).


PATIENTS AND METHODS
Using a dynamic contrast CT, we conducted a retrospective study of 27 patients with convexity (n = 15), falx (n = 6), and parasagittal (n = 6) meningiomas treated in our hospital from January 2016 to September 2018. We set the region of interest on the dural layer and cerebral surface side of meningiomas and calculated the mean CT value in each region. Distribution of blood flow in the tumor was classified into two groups: A, which has a higher CT value of the dural side than that of the brain surface side at every timing, and B, which meets the criteria other than those in group A. Demographic data, preoperative characteristic images, and postoperative complications were compared between the groups.


RESULTS
Twelve and 15 patients were classified into groups A and B, respectively. The extent of adhesions against the cerebral cortex in group A was significantly less severe compared with that in group B (p = 0.038). The rate of postoperative hemorrhage occurrence in group B (53%) was significantly higher than that in group A (8%) (p = 0.04). There were no significant differences in the other preoperative characteristic images or perioperative parameters between groups A and B.


CONCLUSION
A 320-row dynamic contrast CT scanner can detect meningiomas with a high probability of severe adhesion toward the brain surface and postoperative intraparenchymal hematoma.
['Arai|Nobuhiko|N|', 'Mizutani|Katsuhiro|K|', 'Horiguchi|Takashi|T|', 'Akiyama|Takenori|T|', 'Takahashi|Satoshi|S|', 'Yanagisawa|Kaoru|K|', 'Koike|Kazunari|K|', 'Yoshida|Kazunari|K|']
D000328:Adult D000368:Aged D004388:Dura Mater D005260:Female D056973:Four-Dimensional Computed Tomography D006801:Humans D008297:Male D008577:Meningeal Neoplasms D008579:Meningioma D008875:Middle Aged D009389:Neovascularization, Pathologic D019635:Neurosurgical Procedures D019106:Postoperative Hemorrhage D000267:Tissue Adhesions
Meningioma CT-DSA Postoperative hemorrhage 320-row CT Brain adhesion Pial feed