The role of lymphadenectomy in uterine sarcoma: a clinical practical approach based on retrospective analysis.
BACKGROUND
Uterine sarcomas are rare, highly aggressive tumors with an unfavorable prognosis. Only limited data on treatment and outcome are available and the role of lymphadenectomy is controversial for this particular tumor type.


PATIENTS AND METHODS
By performing a retrospective analysis, through clinical practice, we analyzed the impact of lymphadenectomy on patient outcome.


RESULTS
Out of 52 patients, 48 women underwent surgical treatment. Among those, lymphadenectomy was performed in 58%. 10% underwent pelvic and paraaortic lymphadenectomy and 48% underwent pelvic lymphadenectomy alone.


CONCLUSION
In our cohort, surgeons tended to perform paraaortic-plus-pelvic or pelvic-alone lymphadenectomy irrespective of the presence or absence of enlarged lymph nodes. Patients who underwent lymphadenectomy showed a better survival. This observation might indicate a potential role for systematic lymphadenectomy in the surgical treatment of uterine sarcoma. We review on clinical operative decisions, critically with regard to current evidence.
['Hoellen|Friederike|F|', 'Waldmann|Anika|A|', 'Benthin|Stephanie|S|', 'Hanker|Lars|L|', 'Rody|Achim|A|', 'Fischer|Dorothea|D|']
D018195:Adenosarcoma D000328:Adult D000368:Aged D000369:Aged, 80 and over D002296:Carcinosarcoma D005260:Female D006801:Humans D007890:Leiomyosarcoma D008197:Lymph Node Excision D008198:Lymph Nodes D008207:Lymphatic Metastasis D008875:Middle Aged D009367:Neoplasm Staging D012189:Retrospective Studies D014594:Uterine Neoplasms
lymphadenectomy Sarcoma carcinosarcoma leiomyosarcoma uterine cancer