FAST MRI breast screening revisited.
INTRODUCTION
Screening for breast cancer in high-risk women takes about 40 minutes to acquire an MRI scan and is time-intensive to report. There is recent interest in the performance of an abbreviated MRI protocol (FAST) in the screening setting. FAST scans have a reported negative predictive value of 99.8%. This study evaluates the false positive rates (FPR) and recall rates for FAST scans as compared to full diagnostic studies (FD).


METHODS
A database of all screening breast MRI scans performed at our institution between 30 June 2013 and 1 July 2014 (n = 591) was created by one of the researchers, who did not subsequently analyse the MRI scans. The T1W and first post-contrast and subtracted images from each of these scans (FAST protocol) were assessed by experienced breast MRI radiologists, blinded to the final diagnosis. The findings were then compared with the FD result.


RESULTS
The recall rates were 6.6% for FAST scans and 5.8% for FD scans. FPR rates were 4.7% and 3.9% respectively. There is no statistically significant difference in the recall rates or FPR of FAST scans in comparison with full diagnostic studies.


CONCLUSIONS
Given the absence of statistically significant difference in the FPR and recall rates in comparison with FD, FAST scans can replace FD for screening of breast cancer.
['Jain|Manish|M|', 'Jain|Arushi|A|', 'Hyzy|Marek D|MD|', 'Werth|Graziella|G|']
D000328:Adult D000368:Aged D001940:Breast D001943:Breast Neoplasms D005260:Female D006801:Humans D007091:Image Processing, Computer-Assisted D008279:Magnetic Resonance Imaging D008327:Mammography D008875:Middle Aged D012189:Retrospective Studies D055815:Young Adult
screening FAST scan breast MRI