Vitamin D3 in children with allergic asthma in clinical practice.
Asthma is a chronic inflammatory disorder; type 2 inflammation is the most common asthma endotype in childhood. T regulatory cells are functionally and allergen-specifically defective in allergic patients. Vitamin D3 exerts many functions on immune system, mainly concerning T regulatory function. Asthma control is the goal of the asthma treatment. We aimed to stratified a group of 76 consecutive children (50 males, 26 females, mean age 10.4 + 2.2 years) with allergic asthma and visited for the first time at a third-level paediatric clinic during a 3-month period, considering the Vitamin D3 serum levels. The three Vitamin D3 classes were not able to discriminate significant difference for all the parameters considered. In conclusion, Vitamin D3 serum assessment seems to be scarcely useful to pheno/endotyping allergic asthmatic children in clinical practice.
['Licari|Amelia|A|0000-0002-1773-6482', 'Marseglia|Gian Luigi|GL|0000-0003-3662-0159', 'Ciprandi|Giorgio|G|0000-0001-7016-8421']
D001249:Asthma D002648:Child D002762:Cholecalciferol D005260:Female D006801:Humans D008297:Male D014815:Vitamins
Vitamin D3 asthma clinical practice asthma control