Evaluation of six anti-SARS-CoV-2 antibody test kits and practical approaches to optimize the diagnostic performance.
In an investigation of six anti-SARS-CoV-2 antibody kits with different target antigen and methodology, each kit showed comparable performance. As false-positive reactions occurred independently with different kits, specificity increased to 100% when pairs of kits were used. With three-kit combination, both sensitivity (99.1%) and specificity (100%) increased.
['Ko|Jae-Hoon|JH|', 'Joo|Eun-Jeong|EJ|', 'Baek|Jin Yang|JY|', 'Huh|Kyungmin|K|', 'Cho|Sun Young|SY|', 'Kang|Cheol-In|CI|', 'Chung|Doo Ryeon|DR|', 'Kim|Yae-Jean|YJ|', 'Kang|Eun-Suk|ES|', 'Peck|Kyong Ran|KR|']
D000914:Antibodies, Viral D000086382:COVID-19 D000087124:COVID-19 Serological Testing D005189:False Positive Reactions D006801:Humans D011933:Reagent Kits, Diagnostic D060888:Real-Time Polymerase Chain Reaction D000086402:SARS-CoV-2 D012680:Sensitivity and Specificity
Antibody Performance Combination COVID-19 SARS-CoV-2