Rate of reoperation at 1 year for aortic repair vs replacement in aortic regurgitation. A trial sequence analysis of published meta-analysis results.
The pooled estimate of a recent meta-analysis concluded that rate of reoperation at 1 year was significantly higher in Aortic valve repair (8.82% vs 3.70%) as compared with aortic valve replacement in patients with aortic regurgitation (odds ratio = 2.67, 95% confidence interval [1.08, 3.62], P = .03). We performed a trial sequential analysis using the published data of the meta-analysis and found the evidence is not strong enough for the conclusion.
['Kumar|Ashish|A|http://orcid.org/0000-0003-4249-0055', 'Shariff|Mariam|M|http://orcid.org/0000-0001-8799-9678']
D001021:Aortic Valve D001022:Aortic Valve Insufficiency D058385:Cardiac Valve Annuloplasty D019918:Heart Valve Prosthesis Implantation D006801:Humans D015201:Meta-Analysis as Topic D012086:Reoperation D013997:Time Factors
aortic regurgitation aortic valve repair aortic valve replacement trial sequential analysis