Luminol-K3Fe(CN)6 chemiluminescence system for the determination of glipizide.
A rapid and sensitive flow-injection chemiluminescence (CL) method for the determination of glipizide was developed on the basis of finding that glipizide can enhance the CL intensity of the luminol-K3Fe(CN)6 system. In optimum condition, the increased CL intensity was directly proportional to the concentration of glipizide in the range from 4.0×10-8 g/mL to 1.0×10-6 g/mL and the detection limit was 1.0×10-8 g/mL glipizide. The relative standard deviation (RSD) of the developed method was 2.1% with 11 repeated measurements of 1.0×10-7 g/mL glipizide. The developed method has been successfully applied to the analysis of glipizide in its pharmaceutical preparations.
['Chen|Xin|X|', 'Xing|Li-Li|LL|', 'Tang|Yu-Hai|YH|', 'Zhang|Guang-Bin|GB|']
Chemiluminescence Glipizide Flow injection Luminol–K3Fe(CN)6