Tear meniscus volume changes in dacryocystorhinostomy evaluated with quantitative measurement using anterior segment optical coherence tomography.
PURPOSE
To evaluate tear meniscus (TM) changes in external dacryocystorhinostomy (ex-DCR) with quantitative measurement of tear meniscus height (TMH), area (TMA), and volume (TMV) using anterior segment optical coherence tomography (AS-OCT).


METHODS
Twenty-five eyes from 21 patients (11 males and 10 females) with primary acquired nasolacrimal duct obstruction (PANDO) who received ex-DCR from May 2010 to April 2011 were evaluated prospectively on their TMH, TMA, and TMV changes by AS-OCT. Measurements were performed before surgery (Pre) and 2 weeks (2W), 2 months (2M), and 6 months (6M) after surgery. Data were analyzed using Kruskal-Wallis test, Wilcoxon signed-rank test with Bonferroni adjustment, and Spearman's rank correlation coefficient.


RESULTS
All patients had a good clinical course, and there were significant differences in the values of each TM parameter before and after surgery (P < 0.0001). The median values of TMH (mm) throughout the observation period were 0.707 (Pre), 0.334 (2W), 0.278 (2M), and 0.277 (6M). The TMA median values (mm(2)) were 0.1097 (Pre), 0.0483 (2W), 0.0255 (2M), and 0.0224 (6M). The TMV median values (mm(3)) were 0.7799 (Pre), 0.1614 (2W), 0.1071 (2M), and 0.1553 (6M). There were significant differences in TMH, TMA, and TMV reduction at each postoperative visit as compared to preoperative values (P < 0.001). In addition, TMH change 6 months after ex-DCR showed a significant positive correlation with age (r = 0.4434, P = 0.0264).


CONCLUSIONS
The perioperative TM changes in ex-DCR can be evaluated noninvasively and quantitatively by using AS-OCT.
['Ohtomo|Kazuyoshi|K|', 'Ueta|Takashi|T|', 'Fukuda|Reina|R|', 'Usui|Tomohiko|T|', 'Miyai|Takashi|T|', 'Shirakawa|Rika|R|', 'Amano|Shiro|S|', 'Nagahara|Miyuki|M|']
D000328:Adult D000368:Aged D000369:Aged, 80 and over D000869:Anterior Eye Segment D003608:Dacryocystorhinostomy D005260:Female D005500:Follow-Up Studies D006801:Humans D007766:Lacrimal Apparatus Diseases D008297:Male D008875:Middle Aged D011184:Postoperative Period D012189:Retrospective Studies D013500:Surface Tension D013666:Tears D041623:Tomography, Optical Coherence
tear meniscus dacryocystorhinostomy anterior segment optical coherence tomography nasolacrimal duct obstruction