Hepatoprotective phenylethanoid glycosides from Cirsium setosum.
Two new phenylethanoid glycosides, namely β-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1) and β-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(4-hydroxyphenyl)-8-propenoate] (2), together with six phenylethanoid glycosides were isolated from Cirsium setosum. Their structures were elucidated by their spectroscopic data and references. Compounds 2, 4, 5, 7 and 8 (10 μM) exhibited moderate hepatoprotective activities. Compounds (3-8) were obtained from this plant for the first time.
['Ma|Qinge|Q|', 'Guo|Yongming|Y|', 'Luo|Baomin|B|', 'Liu|Wenmin|W|', 'Wei|Rongrui|R|', 'Yang|Chunxia|C|', 'Ding|Chenghua|C|', 'Xu|Xuefeng|X|', 'He|Minghui|M|']
D000818:Animals D031180:Cirsium D006027:Glycosides D006801:Humans D008099:Liver D015394:Molecular Structure D020011:Protective Agents
phenylethanoid glycoside Cirsium setosum hepatoprotective activity