Medicinal Plant Compounds for Combating the Multi-drug Resistant Pathogenic Bacteria: A Review.
BACKGROUND
Globally, people utilize plants as the main source of remedy to heal various ailments. Medicinal plants have been utilized to treat ailments since the invention of modern scientific systems of medicine. The common remedy of infectious diseases mainly depends on the inhibition capacity of compounds or killing potential. The issue may give a clue for the development of a novel antimicrobial agent.


METHODS
Currently, microorganisms which are resistant towards antibiotics are probably a matter of serious concern for the overall well-being of health. At the moment, new therapeutic targets aside from the microorganism wall-based activities are in progress. For instance, the autoinducer molecules produced by the quorum sensing system are used to control antibiotic resistance and biofilm formation.


RESULTS
This therapeutic target is well-studied worldwide, however, the scientific data are not updated and only current studies started to gain insight into its perspective as a target to struggle against infectious diseases. Microbial resistance against antimicrobial compounds is a topic of serious concern in recent time.


CONCLUSION
Hence, this paper aims to confer a current overview of the novel compounds, quorum sensing, quorum quenching, biofilm formation in the development of antibiotic resistance and an update on their importance as a potential target for natural substances.
['Mulat|Mulugeta|M|', 'Pandita|Archana|A|', 'Khan|Fazlurrahman|F|']
D000818:Animals D000900:Anti-Bacterial Agents D000890:Anti-Infective Agents D001419:Bacteria D018441:Biofilms D024901:Drug Resistance, Multiple, Bacterial D006801:Humans D010936:Plant Extracts D010946:Plants, Medicinal D053038:Quorum Sensing
medicinal plant pathogenic bacteria Antibiotics antibiotic resistance biofilm quorum sensing.