Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses.
Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.
['Kim|Sung Jae|SJ|https://orcid.org/0000-0002-8813-012X', 'Kim|Cheongung|C|https://orcid.org/0000-0003-1205-0876', 'Chung|Hee Chun|HC|https://orcid.org/0000-0003-4666-5393', 'Park|Yong Ho|YH|https://orcid.org/0000-0002-4168-6884', 'Park|Kun Taek|KT|https://orcid.org/0000-0001-6177-0373']
D000595:Amino Acid Sequence D000818:Animals D017250:Caliciviridae Infections D017927:Calicivirus, Feline D036022:Capsid Proteins D002371:Cat Diseases D002415:Cats D010802:Phylogeny D056910:Republic of Korea
Feline calicivirus open reading frame 2 phylogenetic analysis genogroup