Impact of Perioperative Hypnosedation on Postmastectomy Chronic Pain: Preliminary Results.
Objectives: The main aim of this prospective nonrandomized study was to evaluate if mastectomy performed with perioperative hypnosedation led to a lower incidence of chronic pain compared with mastectomy under general anesthesia. Methods: Forty-two breast cancer patients who underwent mastectomy either under GA (GA group, n = 21) or HYP (HYP group, n = 21) associated with local and/or regional anesthesia were included. The type of adjuvant therapy as well as the number of reconstructive surgical procedures were well balanced between the 2 groups. The average age of the patients and the type of axillary surgery were also equivalent. Incidence of postmastectomy chronic pain, lymphedema, and shoulder range of motion (ROM) were evaluated after a mean 4-year follow-up. Results: The study shows a statistically significant lower incidence of postmastectomy chronic pain in HYP group (1/21, 1 patient out of 21 experiencing pain) compared with GA group (9/21) with 9 patients out of 21 experiencing pain (P = .008). ROM for shoulder was also less frequently affected in the hypnosedation group, as only 1 patient had decreased ROM, instead of 7 in the other group (P = .04). Conclusions: Our study is the first to hint at the potential benefits of hypnosedation on postmastectomy chronic pain. Despite the limitations of this study (nonrandomized, small sample), preliminary results merit further study of hypnosedation.
['Lacroix|Camille|C|', 'Duhoux|Francois P|FP|', 'Bettendorff|Julie|J|', 'Watremez|Christine|C|', 'Roelants|Fabienne|F|', 'Docquier|Marie-Agnes|MA|', 'Potié|Arnaud|A|', 'Coyette|Maude|M|', 'Gerday|Amandine|A|', 'Samartzi|Vasiliki|V|', 'Piette|Philippe|P|', 'Piette|Nathan|N|', 'Berliere|Martine|M|0000-0002-6472-9867']
D000768:Anesthesia, General D001943:Breast Neoplasms D016022:Case-Control Studies D059350:Chronic Pain D003131:Combined Modality Therapy D005260:Female D006801:Humans D006991:Hypnosis, Anesthetic D008408:Mastectomy D008875:Middle Aged D010149:Pain, Postoperative D011446:Prospective Studies
mastectomy breast cancer benefits of hypnosis hypnoanalgesia postmastectomy pain syndrome