A 512-Pixel, 51-kHz-Frame-Rate, Dual-Shank, Lens-less, Filter-less Single Photon Avalanche Diode CMOS Neural Imaging Probe.
We present an implantable single photon shank-based imager, monolithically integrated onto a single CMOS IC. The imager comprises of 512 single photon avalanche diodes distributed along two shanks, with a 6-bit depth in-pixel memory and an on-chip digital-to-time converter. To scale down the system to a minimally invasive form factor, we substitute optical filtering and focusing elements with a time-gated, angle-sensitive detection system. The imager computationally reconstructs the position of fluorescent sources within a three-dimensional volume of 3.4 mm × 600 µm × 400 µm.
['Choi|Jaebin|J|', 'Taal|Adriaan J|AJ|', 'Pollmann|Eric H|EH|', 'Lee|Changhyuk|C|', 'Kim|Kukjoo|K|', 'Moreaux|Laurent C|LC|', 'Roukes|Michael L|ML|', 'Shepard|Kenneth L|KL|']
Single photon avalanche diode CMOS Compressed sensing Neural probe Time-gated fluorescence imaging