Presence of rare hepatitis C virus subtypes, 2j, 2k, and 2r in Mexico City as identified by sequencing.
The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT-1a, nine with GT-2b and four with GT-3a. Two rare subtypes were detected: GT-2j in two patients and GT-2r in one patient. Three patients had mixed infections: one with GT-2k + 2j and two with GT-1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.
['Uribe-Noguez|Luis Antonio|LA|0000-0003-2452-782X', 'Ocaña-Mondragón|Alicia|A|', 'Mata-Marín|José Antonio|JA|', 'Gómez-Torres|María Elena|ME|', 'Ribas-Aparicio|Rosa María|RM|', 'de la Luz Martínez-Rodríguez|María|M|']
D020121:5' Untranslated Regions D000328:Adult D002947:Cities D005260:Female D014644:Genetic Variation D005838:Genotype D060005:Genotyping Techniques D016174:Hepacivirus D006526:Hepatitis C D006801:Humans D008297:Male D008800:Mexico D008875:Middle Aged D017422:Sequence Analysis, DNA D014758:Viral Core Proteins D014759:Viral Envelope Proteins D017361:Viral Nonstructural Proteins
hepatitis C virus epidemiology evolution genetic variability virus classification