Whole mitochondrial genome sequencing and analysis for chronic obstructive pulmonary disease rat strain.
Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. We sequenced a complete mitochondrial genome sequence of a rat chronic obstructive pulmonary disease rat strain for the first time. The total length of the mitochondrial genome was 16,310 bp and coding 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.
['Jiang|Zhi-Ming|ZM|', 'Zhao|Qing-Sheng|QS|', 'Xu|Yong-Qing|YQ|', 'Li|Tao|T|', 'Jie|Jian|J|', 'Zhang|Zhong-Hui|ZH|']
D000818:Animals D018387:Codon, Initiator D018388:Codon, Terminator D004272:DNA, Mitochondrial D004195:Disease Models, Animal D003576:Electron Transport Complex IV D054629:Genome, Mitochondrial D009245:NADH Dehydrogenase D016366:Open Reading Frames D029424:Pulmonary Disease, Chronic Obstructive D012335:RNA, Ribosomal D012343:RNA, Transfer D051381:Rats D017422:Sequence Analysis, DNA
mitochondrial genome chronic obstructive pulmonary disease Cancer