Acanthamoeba Infection in a Drowning Child.
BACKGROUND
Acanthamoeba infection is a potential life-threatening complication of drowning. The management of drowning-associated Acanthamoeba infection remains controversial. Survival reports on Acanthamoeba infection have been on case reports only.


CASE DETAILS
A 2-year-old, previously healthy Indonesian boy presented with decreased consciousness and inadequate breathing, followingdrowning. The event was unsupervised with unknown estimated time of submersion. Resuscitation was commenced and mechanical ventilated was applied. Sputum specimen revealed alive Acanthamoeba with pseudopods and cysts. Sputum culture resulted in Pseudomonas aeruginosa and cerebrospinal fluid was supportive for Acanthamoeba with 1-3 trophozoites and cyst. Imaging of the head showed cerebral edema and encephalitis. The patient received intravenous ceftazidime, metronidazole, fluconazole and rifampicin. The patient's consciousness was unsatisfactory regained resulting in an altered mental status.


CONCLUSION
No treatment so far has given a succesful outcome for Acanthamoeba. In this case, management with metronidazole, rifampicin and fluconazole showed regain of consciousness resulting in altered mental status.
['Gunawan|Prastiya Indra|PI|', 'Idarto|Areta|A|', 'Saharso|Darto|D|']
D000048:Acanthamoeba D000562:Amebiasis D000890:Anti-Infective Agents D002675:Child, Preschool D003243:Consciousness D003560:Cysts D004332:Drowning D006801:Humans D008297:Male D001523:Mental Disorders D011550:Pseudomonas aeruginosa D053058:Trophozoites D014474:Unconsciousness
Acanthamoeba Encephalitis Pneumonia