Maternal Nutrition and Neurodevelopment: A Scoping Review.
In this scoping review, we examined the association between maternal nutrition during pregnancy and neurodevelopment in offspring. We searched the Pubmed and ScienceDirect databases for articles published from 2000 to 2020 on inadequate intake of vitamins (B12, folate, vitamin D, vitamin A, vitamin E, vitamin K), micronutrients (cooper, iron, creatine, choline, zinc, iodine), macronutrients (fatty acids, proteins), high fat diets, ketogenic diets, hypercaloric diets, and maternal undernutrition. Some older relevant articles were included. The search produced a total of 3590 articles, and 84 studies were included in the qualitative synthesis. Data were extracted and analyzed using charts and the frequency of terms used. We concluded that inadequate nutrient intake during pregnancy was associated with brain defects (diminished cerebral volume, spina bifida, alteration of hypothalamic and hippocampal pathways), an increased risk of abnormal behavior, neuropsychiatric disorders (ASD, ADHD, schizophrenia, anxiety, depression), altered cognition, visual impairment, and motor deficits. Future studies should establish and quantify the benefits of maternal nutrition during pregnancy on neurodevelopment and recommend adequate supplementation.
['Cortés-Albornoz|María Camila|MC|0000-0003-0733-5105', 'García-Guáqueta|Danna Paola|DP|0000-0002-3565-3971', 'Velez-van-Meerbeke|Alberto|A|', 'Talero-Gutiérrez|Claudia|C|0000-0003-1601-5015']
D000328:Adult D004032:Diet D005260:Female D006801:Humans D007223:Infant D007231:Infant, Newborn D008297:Male D044342:Malnutrition D018811:Maternal Exposure D039382:Maternal Nutritional Physiological Phenomena D018977:Micronutrients D065886:Neurodevelopmental Disorders D000078622:Nutrients D009752:Nutritional Status D011247:Pregnancy D011248:Pregnancy Complications D011297:Prenatal Exposure Delayed Effects D014815:Vitamins
maternal nutrition neurodevelopment nutrients neuropsychiatric disorders cognitive abilities