Chiral Separations by Countercurrent Chromatography.
Chiral separations by countercurrent chromatography are mainly divided into two types: homogeneous chiral selector addition and interfacial chiral ligand exchange. In this chapter, we describe two methods for the enantioseparation of phenylsuccinic acid and α-hydroxy acids by high-speed countercurrent chromatography using hydroxypropyl-β-cyclodextrin and N-n-dodecyl-L-proline as chiral selectors for both above mentioned modes.
['Tong|Sheng-Qiang|SQ|']
D000073738:2-Hydroxypropyl-beta-cyclodextrin D002851:Chromatography, High Pressure Liquid D003377:Countercurrent Distribution D006880:Hydroxy Acids D008024:Ligands D013237:Stereoisomerism D019802:Succinic Acid
Chiral separation Countercurrent chromatography Homogeneous chiral selector Chiral ligand exchange Biphasic solvent system