Advances in the management of diabetes: therapies for type 2 diabetes.
The incidence of type 2 diabetes is rapidly rising worldwide leading to an increasing burden of cardiovascular and microvascular complications. The aim of treatment of the condition is to improve quality of life and reduce such complications. To this end, improvement in glucose control remains an important consideration. In recent years, important therapeutic advances have occurred in the management of hyperglycaemia in people with type 2 diabetes. These include the use of dipeptidylpeptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists and sodium glucose transporter-2 inhibitors. The latter two classes appear to have some specific beneficial effects on cardiovascular and renal outcomes, independent of their antihyperglycaemic effects. This review aims to outline the current state of diagnosis and management of diabetes for the general physician, with a particular focus on new therapeutic agents for management of glucose in patients with type 2 diabetes.
['Tsoutsouki|Jovanna|J|', 'Wunna|Wunna|W|', 'Chowdhury|Aisha|A|', 'Chowdhury|Tahseen Ahmad|TA|http://orcid.org/0000-0001-8878-2331']
D001786:Blood Glucose D003924:Diabetes Mellitus, Type 2 D054873:Dipeptidyl-Peptidase IV Inhibitors D000067757:Glucagon-Like Peptide-1 Receptor D006442:Glycated Hemoglobin A D000085002:Glycemic Control D006801:Humans D007004:Hypoglycemic Agents D008687:Metformin D000077203:Sodium-Glucose Transporter 2 Inhibitors D013453:Sulfonylurea Compounds D045162:Thiazolidinediones
diabetic nephropathy & vascular disease