Are Eating Disorders Risk Factors for Type 2 Diabetes? A Systematic Review and Meta-analysis.
RECENT FINDINGS
Eating disorders (ED) affect energy intake modifying body fat depots. Prior evidence suggests that binge eating disorder (BED) and bulimia nervosa (BN) could increase the risk for type 2 diabetes (T2D), while anorexia nervosa (AN) could reduce it.


PURPOSE OF REVIEW
A systematic review and meta-analysis were conducted to evaluate if ED are risk factors for T2D. Ten studies were selected out of 1057 screened. Meta-analysis of six studies with T2D as outcome is reported. Among cross-sectional studies, both BED (OR 3.69, 95% CI [1.12-12.12]) and BN (OR 3.45 [1.92-6.1]) increased the risk of T2D, while AN was not associated with lower risk (OR 0.87 [0.40-1.88]). Cohort studies showed increased risk of T2D with BN (RR 1.7 [1.2-2.5]), and decreased risk with AN (RR 0.71 [0.52-0.98]), but for BED the association was less clear (OR 3.34 [0.85-13.12]). Limitations of studies and recommendations for future research are presented.
['Nieto-Martínez|Ramfis|R|', 'González-Rivas|Juan P|JP|', 'Medina-Inojosa|José R|JR|', 'Florez|Hermes|H|']
D003430:Cross-Sectional Studies D003924:Diabetes Mellitus, Type 2 D001068:Feeding and Eating Disorders D005260:Female D006801:Humans D012307:Risk Factors
Eating disorders Binge eating disorder Bulimia nervosa Anorexia nervosa Diabetes mellitus type 2 Night eating syndrome