Cardiac MRI right ventricle / left ventricle (RV/LV) volume ratio improves detection of RV enlargement.
PURPOSE
To determine the normal range of the ratio of right ventricular (RV) end-diastolic volume to left ventricular (LV) end-diastolic volume by magnetic resonance imaging (MRI) and examine whether combining this volume ratio with RVEDV indexed to body surface area (RVEDVi) increased the detection of RV dilation in patients with pulmonary arterial hypertension (PAH).


MATERIALS AND METHODS
MRI-derived ventricular function and volumes were measured in a control group (n = 152) and in patients with PAH (n = 46). Images were acquired with a 1.5T Siemens or a 1.5T Philips scanner using a steady-state free procession sequence. Proposed criteria for the detection of RV enlargement, including RVEDVi alone, RV/LV volume ratio alone, and combining both criteria, were evaluated in both groups.


RESULTS
The range (mean ± 2 standard deviations) for the volume ratio in the normal population was found to be 0.906-1.266; there was no difference between genders (P = 0.70). Combining this ratio with RVEDVi detected RV enlargement in 21.7% (P < 0.001) PAH patients (volume ratio ≥1.27) who were not identified by the RVEDVi alone (>104 mL/m(2) for females and >113 mL/m(2) for males).


CONCLUSION
Combining RV/LV volume ratio with indexed RVEDV increased detection of RV enlargement in a PAH population. This result may have potential impact in RV size assessment. J. Magn. Reson. Imaging 2016;43:1379-1385.
['Altmayer|Stephan P L|SP|', 'Patel|Amit R|AR|', 'Addetia|Karima|K|', 'Gomberg-Maitland|Mardi|M|', 'Forfia|Paul R|PR|', 'Han|Yuchi|Y|']
D000293:Adolescent D000328:Adult D000368:Aged D000465:Algorithms D002306:Cardiac Volume D005260:Female D006352:Heart Ventricles D006801:Humans D017380:Hypertrophy, Right Ventricular D007089:Image Enhancement D007090:Image Interpretation, Computer-Assisted D021621:Imaging, Three-Dimensional D019028:Magnetic Resonance Imaging, Cine D008297:Male D008875:Middle Aged D015203:Reproducibility of Results D012680:Sensitivity and Specificity D013318:Stroke Volume D055815:Young Adult
MRI ratio RVEDV right ventricular size