A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract.
A new biflavone, 6,2',3″,5″,4‴-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.
['Sabudak|Temine|T|', 'Kaya|Oktay|O|', 'Cukurova|Elif|E|']
D000818:Animals D044946:Biflavonoids D001786:Blood Glucose D003921:Diabetes Mellitus, Experimental D005638:Fruit D007004:Hypoglycemic Agents D008297:Male D008807:Mice, Inbred BALB C D015394:Molecular Structure D010936:Plant Extracts D018515:Plant Leaves D051381:Rats D017208:Rats, Wistar D032322:Solanum D023382:Toxicity Tests, Acute
biflavonoid Solanum dulcamara anti-hyperglycaemic activity Solonaceae