The Asia-Pacific Society of Cardiology (APSC) Expert Committee Consensus Recommendations for Assessment of Suspected Acute Coronary Syndrome Using High-Sensitivity Cardiac Troponin T in the Emergency Department.
The Asia-Pacific Society of Cardiology (APSC) high-sensitivity troponin T (hs-TnT) consensus recommendations and rapid algorithm were developed to provide guidance for healthcare professionals in the Asia-Pacific region on assessing patients with suspected acute coronary syndrome (ACS) using a hs-TnT assay. Experts from Asia-Pacific convened in 2 meetings to develop evidence-based consensus recommendations and an algorithm for appropriate use of the hs-TnT assay. The Expert Committee defined a cardiac troponin assay as a high-sensitivity assay if the total imprecision is ≤10% at the 99th percentile of the upper reference limit and measurable concentrations below the 99th percentile are attainable with an assay at a concentration value above the assay's limit of detection for at least 50% of healthy individuals. Recommendations for single-measurement rule-out/rule-in cutoff values, as well as for serial measurements, were also developed. The Expert Committee also adopted similar hs-TnT cutoff values for men and women, recommended serial hs-TnT measurements for special populations, and provided guidance on the use of point-of-care troponin T devices in individuals suspected of ACS. These recommendations should be used in conjunction with all available clinical evidence when making the diagnosis of ACS.
['Tan|Wei Chieh Jack|WCJ|', 'Inoue|Kenji|K|', 'AbdelWareth|Laila|L|', 'Giannitsis|Evangelos|E|', 'Kasim|Sazzli|S|', 'Shiozaki|Masayuki|M|', 'Aw|Tar Choon|TC|', 'Cheng|Federick|F|', 'Dung|Ho Thuong|HT|', 'Li|Yi-Heng|YH|', 'Lim|Swee Han|SH|', 'Lukito|Antonia Anna|AA|', 'Than|Martin|M|', 'Chu|Fang-Yeh|FY|', 'Devasia|Tom|T|', 'Lee|Chien-Chang|CC|', 'Phrommintikul|Arintaya|A|', 'Youn|Jong-Chan|JC|', 'Chew|Derek P|DP|']
D054058:Acute Coronary Syndrome D000465:Algorithms D015415:Biomarkers D002309:Cardiology D016507:Cardiology Service, Hospital D032921:Consensus D003661:Decision Support Techniques D003663:Decision Trees D003935:Diagnostic Techniques, Cardiovascular D004636:Emergency Service, Hospital D006801:Humans D011237:Predictive Value of Tests D011379:Prognosis D015203:Reproducibility of Results D012955:Societies, Medical D020107:Troponin T D015854:Up-Regulation
Asia-Pacific Consensus recommendations Acute coronary syndrome High-sensitivity troponin T