Visuospatial Organization and Recall in Cerebellar Ataxia.
Poor visuospatial skills can disrupt activities of daily living. The cerebellum has been implicated in visuospatial processing, and patients with cerebellar injury often exhibit poor visuospatial skills, as measured by impaired memory for the figure within the Rey-Osterrieth complex figure task (ROCF). Visuospatial skills are an inherent aspect of the ROCF; however, figure organization (i.e., the order in which the figure is reconstructed by the participant) can influence recall ability. The objective of this study was to examine and compare visuospatial and organization skills in people with cerebellar ataxia. We administered the ROCF to patients diagnosed with cerebellar ataxia and healthy controls. The cerebellar ataxia group included patients that carried a diagnosis of spinocerebellar ataxia (any subtype), autosomal dominant cerebellar ataxia, or cerebellar ataxia with unknown etiology. Primary outcome measures were organization and recall performance on the ROCF, with supplemental information derived from cognitive tests of visuospatial perception, working memory, processing speed, and motor function. Cerebellar ataxia patients revealed impaired figure organization relative to that of controls. Figure copy was impaired in the patients, but their subsequent recall performance was normal, suggesting compensation from initial organization and copying strategies. In controls, figure organization predicted recall performance, but this relationship was not observed in the patients. Instead, processing speed predicted patients' recall accuracy. Supplemental tasks indicated that visual perception was intact in the cerebellar ataxia group and that performance deficits were more closely tied to organization strategies than with visuospatial skills.
['Slapik|Mitchell|M|', 'Kronemer|Sharif I|SI|', 'Morgan|Owen|O|', 'Bloes|Ryan|R|', 'Lieberman|Seth|S|', 'Mandel|Jordan|J|', 'Rosenthal|Liana|L|', 'Marvel|Cherie|C|http://orcid.org/0000-0002-2818-8303']
D000328:Adult D000368:Aged D002524:Cerebellar Ataxia D005260:Female D006225:Hand D006801:Humans D008297:Male D011939:Mental Recall D008875:Middle Aged D009483:Neuropsychological Tests D011597:Psychomotor Performance D013028:Space Perception D065852:Spatial Memory D014796:Visual Perception
Visuospatial Organization Ataxia Cerebellum Memory Cognition