Functional connectivity of dorsal and ventral frontoparietal seed regions during auditory orienting.
Our ability to refocus auditory attention is vital for even the most routine day-to-day activities. Shifts in auditory attention can be initiated "voluntarily," or triggered "involuntarily" by unexpected novel sound events. Here we employed psychophysiological interaction (PPI) analyses of auditory functional MRI data, to compare functional connectivity patterns of distinct frontoparietal cortex regions during cued voluntary vs. novelty-driven involuntary auditory attention shifting. Overall, our frontoparietal seed regions exhibited significant PPI increases with auditory cortex (AC) areas during both cued and novelty-driven orienting. However, significant positive PPI patterns associated with voluntary auditory attention (cue>novel task regressor), but mostly absent in analyses emphasizing involuntary orienting (novel>cue task regressor), were observed with seeds within the frontal eye fields (FEF), superior parietal lobule (SPL), and right supramarginal gyri (SMG). In contrast, significant positive PPIs associated selectively with involuntary orienting were observed between ACs and seeds within the bilateral anterior interior frontal gyri (IFG), left posterior IFG, SMG, and posterior cingulate cortices (PCC). We also found indices of lateralization of different attention networks: PPI increases selective to voluntary attention occurred primarily within right-hemispheric regions, whereas those related to involuntary orienting were more frequent with left-hemisphere seeds. In conclusion, despite certain similarities in PPI patterns across conditions, the more dorsal aspects of right frontoparietal cortex demonstrated wider connectivity during cued/voluntary attention shifting, whereas certain left ventral frontoparietal seeds were more widely connected during novelty-triggered/involuntary orienting. Our findings provide partial support for distinct attention networks for voluntary and involuntary auditory attention.
['Rossi|Stephanie|S|', 'Huang|Samantha|S|', 'Furtak|Sharon C|SC|', 'Belliveau|John W|JW|', 'Ahveninen|Jyrki|J|']
D000161:Acoustic Stimulation D000328:Adult D001288:Attention D001307:Auditory Perception D001931:Brain Mapping D003463:Cues D005260:Female D005625:Frontal Lobe D006801:Humans D008279:Magnetic Resonance Imaging D008297:Male D009434:Neural Pathways D009949:Orientation D010296:Parietal Lobe D011601:Psychophysics D014836:Volition D055815:Young Adult
Auditory attention Psychophysiological interaction Auditory cortex Involuntary attention Voluntary orienting fMRI