CMR in the Evaluation of Diastolic Dysfunction and Phenotyping of HFpEF: Current Role and Future Perspectives.
Heart failure with preserved ejection fraction presents a challenging diagnosis given a heterogeneous patient population and limited therapeutic options. Diastolic function assessment using echocardiography has been a cornerstone in the work-up and is as important as systolic functional assessment. There has been increased awareness to the potential utility of cardiac magnetic resonance (CMR) imaging over the past decade as a promising, radiation-free, robust imaging modality providing an unrestricted field of view and high-resolution images for global and regional functional assessment. CMR provides early markers for detecting myocardial disease using tissue characterization imaging, which might prove useful to improve diagnosis and management. Over the years, several studies have examined CMR-derived diastolic functional indices, including transmitral and pulmonary venous velocities, left ventricular and left atrial strain using myocardial tagging, and, more recently, feature tracking. The relevance of imaging-based diastolic function indices and their clinical application across different modalities is increasingly recognized.
['Chamsi-Pasha|Mohammed A|MA|', 'Zhan|Yang|Y|', 'Debs|Dany|D|', 'Shah|Dipan J|DJ|']
D016279:Atrial Function, Left D003971:Diastole D006333:Heart Failure D006801:Humans D019028:Magnetic Resonance Imaging, Cine D010641:Phenotype D011237:Predictive Value of Tests D011379:Prognosis D013318:Stroke Volume D018487:Ventricular Dysfunction, Left D016277:Ventricular Function, Left
cardiac magnetic resonance T1 mapping extracellular volume map feature-tracking CMR imaging phase-contrast imaging