Epicardial Brugada syndrome ablation unmasking inferior J waves.
Patients with Brugada syndrome are at risk of life-threatening ventricular arrhythmias. Epicardial substrate ablation for Brugada syndrome has been described as a means of controlling these arrhythmias and recent reports describe elimination of the Brugada phenotype with ablation. We describe a unique case in which a patient developed inferior J waves with an early repolarization-type electrocardiogram following successful epicardial infundibular substrate ablation (which eliminated the Brugada syndrome electrocardiogram on ajmaline challenge). We discuss the likely underlying pathophysiology responsible for this phenomenon, its relationship to the anatomic obstacles encountered during epicardial ablation, and the implications for long-term arrhythmic risk.
['Lee|Adam|A|http://orcid.org/0000-0002-0189-171X', 'Kohler|Heidi|H|', 'Wright|Daniel|D|', 'Haqqani|Haris M|HM|']
D000328:Adult D053840:Brugada Syndrome D017115:Catheter Ablation D017023:Coronary Angiography D004562:Electrocardiography D006801:Humans D008279:Magnetic Resonance Imaging D008297:Male
Brugada syndrome J waves ajmaline epicardial ablation early repolarization