Anti-fatigue activity of a novel polysaccharide conjugates from Ziyang green tea.
The aim of this study was to investigate the anti-fatigue activity of polysaccharides from Ziyang green tea. Polysaccharides were isolated from Ziyang green tea and its physicochemical properties were analyzed. Meanwhile, a 4-week weight-loaded swimming test of mice was established and polysaccharides were orally administrated during exercise. The biochemical parameters related to fatigue were determined, such as exhaustive time, blood urea nitrogen (BUN), blood lactate acid (Bla) levels and lactic dehydrogenase (LDH) activity in serum, Superoxide dismutase (SOD), Glutathione peroxidase (GSH-Px) activities, Malondialdehyde (MDA) and glycogen levels in skeletal muscle. The results demonstrated that polysaccharide from Ziyang green tea was a selenium-polysaccharide-protein conjugate (Se-TP), and Se-TP administration significantly prolonged exhaustive time and increased glycogen level and GSH-Px activity in muscle, in addition, markedly decreased BUN, Bla levels and LDH activity in serum and MDA level in muscle. In conclusion, Se-TP treatment can significantly improve exercise-induced fatigue and decrease the oxidative stress induced by the exhaustive exercise.
['Chi|Aiping|A|', 'Li|Hong|H|', 'Kang|Chenzhe|C|', 'Guo|Huanhuan|H|', 'Wang|Yimin|Y|', 'Guo|Fei|F|', 'Tang|Liang|L|']
D000595:Amino Acid Sequence D000818:Animals D005221:Fatigue D008297:Male D051379:Mice D008970:Molecular Weight D009005:Monosaccharides D010805:Physical Conditioning, Animal D010936:Plant Extracts D011134:Polysaccharides D013662:Tea
Polysaccharide Exercise-induced fatigue Selenium