Improved metagenomic analysis with Kraken 2.
Although Kraken's k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed fivefold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis.
['Wood|Derrick E|DE|', 'Lu|Jennifer|J|', 'Langmead|Ben|B|0000-0003-2437-1976']
D056186:Metagenomics D012984:Software
Metagenomics Alignment-free methods Metagenomics classification Microbiome Minimizers Probabilistic data structures