Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study.
BACKGROUND
Scalp psoriasis is a major therapeutic challenge due to the hindrance caused by hair. Treatment with the 308-nm excimer lamp is purported to provide many benefits over conventional phototherapy. This retrospective study evaluates the efficacy, safety, and effective dosage of 308-nm excimer light in the treatment of scalp psoriasis.


METHODS
We retrospectively reviewed the medical records of patients with scalp psoriasis who received treatment with 308-nm excimer light. Clinical and epidemiological data as well as details regarding treatment were statistically analyzed to determine the treatment outcomes.


RESULTS
Twenty patients with scalp psoriasis were included in the study. Their mean age was 47.45 ± 17.93 years. Eleven patients responded to treatment at the end of 10 sessions. The median baseline Psoriatic Scalp Severity Index (PSSI) was 12 (range, 3-32). At the end of the protocol, the median PSSI was 4.5 (range, 0-24), indicating a statistically significant reduction (P < 0.001). Common adverse effects included erythema, irritation, and desquamation.


CONCLUSION
The 308-nm excimer light appears to be an effective and safe modality that requires short treatment time. The modality could be considered as an alternative or adjuvant treatment for scalp psoriasis.
['Rattanakaemakorn|Ploysyne|P|', 'Phusuphitchayanan|Phanitchanat|P|', 'Pakornphadungsit|Kallapan|K|', 'Thadanipon|Kunlawat|K|', 'Suchonwanit|Poonkiat|P|https://orcid.org/0000-0001-9723-0563']
D000328:Adult D000368:Aged D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D011565:Psoriasis D012189:Retrospective Studies D012449:Safety D012535:Scalp D014467:Ultraviolet Therapy
excimer lamp scalp psoriasis phototherapy excimer light excimer laser