Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors.
BACKGROUND/AIMS
To evaluate the yields and utility of 19-gauge (G) Trucut biopsy (TCB) versus 22 G fine needle aspiration (FNA) for diagnosing gastric subepithelial tumors (SETs).


METHODS
We retrieved data for 152 patients with a gastric SET larger than 2 cm who had undergone endoscopic ultrasonography (EUS)-guided 19 G TCB (n=90) or 22 G FNA (n=62). Relevant clinical, tumor-specific, and EUS procedural information was reviewed retrospectively.


RESULTS
A specific diagnosis was made for 76 gastrointestinal stromal tumors (GISTs) and 51 non-GIST SETs. The diagnostic yield of TCB was greater than that of FNA (77.8% vs. 38.7%, p<0.001). The percentage of non-diagnostic specimens (suspicious and insufficient) was significantly lower in the TCB group (6.7% and 15.5%, respectively) than in the FNA group (22.6% and 38.7%, respectively; both p<0.001). TCB accurately diagnosed 90.9% of GISTs and 81.1% of non-GIST SETs, whereas FNA accurately diagnosed 68.8% of GISTs and 14.3% of non-GIST SETs. There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs. FNA, 3.3% vs. 8.1%; p=0.27).


CONCLUSIONS
Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.
['Na|Hee Kyong|HK|', 'Lee|Jeong Hoon|JH|', 'Park|Young Soo|YS|', 'Ahn|Ji Yong|JY|', 'Choi|Kwi-Sook|KS|', 'Kim|Do Hoon|DH|', 'Choi|Kee Don|KD|', 'Song|Ho June|HJ|', 'Lee|Gin Hyug|GH|', 'Jung|Hwoon-Yong|HY|', 'Kim|Jin-Ho|JH|']
Subepithelial tumors Biopsy, large-core needle Endoscopic ultrasound-guided fine needle aspiration Endosonography Stomach