Normalized handgrip strength and future risk of hypertension: findings from a prospective cohort study.
Previous reports of an association between handgrip strength (HGS) and the risk of hypertension have utilized cross-sectional designs. We aimed to assess the prospective association between HGS and hypertension risk in a general population. Handgrip strength was assessed at baseline in 463 Finnish men and women aged 61-73 years. Handgrip strength was normalized (HGS/body weight2/3). After 16 years median follow-up, 110 hypertension cases occurred. Comparing the extreme tertiles of normalized HGS, the multivariable adjusted hazard ratio (95% CI) for hypertension was 0.63 (0.38-1.04). Previous evidence of associations may have been driven by study design limitations such as lack of temporality.
['Kunutsor|Setor K|SK|0000-0002-2625-0273', 'Mäkikallio|Timo H|TH|', 'Voutilainen|Ari|A|0000-0002-0664-2675', 'Hupin|David|D|', 'Laukkanen|Jari A|JA|']
Handgrip strength hypertension cohort study risk factor