Systemic Modelling in Bioethics.
We present here a new method for bioethics: systemic modelling. In this method, the complex phenomenon being studied (e.g. personalized medicine, genetic testing, gene therapy, genetically modified organisms) is modelled as a whole, to shed light on its organization and functioning, and major (bio)ethical issues and solutions for their resolution are then identified. This systemic modelling method is ideal for use in the identification of solutions, rather than their validation, with other methods then used to test the solutions found. We provide a description and reproducible instructions for the application of systemic modelling in bioethics, together with a brief example of the application of this method to the study of the impact of personalized medicine on French society.
['Stoeklé|Henri-Corto|HC|', 'Charlier|Philippe|P|', 'Mamzer-Bruneel|Marie-France|MF|', 'Hervé|Christian|C|', 'Vogt|Guillaume|G|']
D001675:Bioethics D026689:Ethical Analysis D005820:Genetic Testing D015316:Genetic Therapy D006801:Humans D008962:Models, Theoretical D030781:Organisms, Genetically Modified D057285:Precision Medicine D013597:Systems Analysis
systemic modelling Bioethics personalized medicine complex phenomena