Brucellar epididymo-orchitis: a retrospective multicenter study of 28 cases and review of the literature.
OBJECTIVE
To review retrospectively the clinical symptoms, laboratory findings and treatment outcomes of patients with Brucellar epididymo-orchitis.


MATERIAL AND METHOD
Retrospective data of 28 patients with Brucellar epididymo-orchitis who admitted to four medical centers between 2005 and 2013 were retrospectively reviewed. Positive blood culture, positive Rose Bengal test results or high agglutination titres of ≥ 1/160 with the positive clinical and ultrasonographic findings of orchitis were accepted as the main criteria for Brucellar epididymo-orchitis.


RESULTS
The mean patient age was 31 ± 16.9 years. Testicular involvement was on the left side in 16 patients and on the right side in 11 patients, one had bilateral disease. Testicular pain and swelling were the most common symptoms and elevation of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and leucocytosis were the most common laboratory findings. Initial treatment was orchidectomy in six patients due to malignancy suspicion. All but three patients were successfully treated with antibiotic combinations of rifampicin, doxycycline and streptomycin. Two of three treatment resistant patients underwent orchidectomy.


CONCLUSION
Brucellosis is a common cause of epididymo-orchitis in endemic regions. Early diagnosis and treatment is crucial in the management and thus it must be kept in mind in endemic and non-endemic regions.
['Savasci|Umit|U|', 'Zor|Murat|M|', 'Karakas|Ahmet|A|', 'Aydin|Emsal|E|', 'Kocaaslan|Ramazan|R|', 'Oren|N Cem|NC|', 'Coskun|Omer|O|', 'Turhan|Vedat|V|', 'Gul|H Cem|HC|', 'Cicek|A Fuat|AF|', 'Aydur|Emin|E|', 'Eyigun|Can Polat|CP|']
D000293:Adolescent D000328:Adult D000368:Aged D000900:Anti-Bacterial Agents D002002:Brucella D002006:Brucellosis D002648:Child D004338:Drug Combinations D004823:Epididymitis D006801:Humans D008297:Male D008875:Middle Aged D009919:Orchiectomy D009920:Orchitis D012189:Retrospective Studies D016896:Treatment Outcome D014421:Turkey D055815:Young Adult
Orchitis Brucella Epididymis Granulomatous Testis