Serological evolution in early syphilis.
INTRODUCTION
The evolution of syphilis after treatment could be affected by different factors, for example HIV. In consequence, HIV positive patients are sometimes treated with more doses of penicillin (PBG). The aim of the study is to describe and compare the serological evolution by different factors in patients with early syphilis in Barcelona.


METHODS
The serological control was made over the following year. A time analysis was performed through the study of Kaplan- Meier curves.


RESULTS
The serological control was made in 208 patients, 42.5% of whom were HIV-positive. In a Kaplan-Meier curve the median of days needed to observe the cure was 99 [97-105] without differences depending on HIV, previous syphilis, stage or RPR titters. A better evolution was observed in patients treated with doxycycline P=.02.


CONCLUSIONS
The serological evolution is similar in HIV-negative and HIV-positive patients treated according to current recommendations, observing the cure at 3 month after treatment.
['Arando|Maider|M|', 'Mota-Foix|Miriam|M|', 'Armegol|Pere|P|', 'Barberá|María Jesús|MJ|', 'Esperalba|Juliana|J|', 'Vall-Mayans|Martí|M|']
D000328:Adult D000900:Anti-Bacterial Agents D005260:Female D015658:HIV Infections D006801:Humans D008297:Male D010406:Penicillins D011446:Prospective Studies D012074:Remission Induction D013030:Spain D013587:Syphilis D013588:Syphilis Serodiagnosis D013997:Time Factors
Serological evolution Early syphilis Evolución serológica Human immunodeficiency virus Sífilis precoz Virus de la inmunodeficiencia humana