Lung nodule and functional changes in smokers after smoking cessation short-term treatment.
BACKGROUND
Tobacco smoke causes lung disfunction and inflammation.


METHODS
Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy.


RESULTS
A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p < .0001), heart rate reduction (p < .01), and FEV1 increase (p < .0001) was recorded.


CONCLUSIONS
Smoking cessation reduces number and size of lung nodules and improves in lung functionality.
['Maci|Eliana|E|', 'Comito|Francesca|F|', 'Frezza|Anna Maria|AM|', 'Tonini|Giuseppe|G|', 'Pezzuto|Aldo|A|']
D002248:Carbon Monoxide D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D055613:Multiple Pulmonary Nodules D010100:Oxygen D010313:Partial Pressure D012129:Respiratory Function Tests D012189:Retrospective Studies D012907:Smoking D016540:Smoking Cessation
Smoking cessation Tobacco High resolution tomography Lung nodule evolution