Platelet counts in autosomal dominant polycystic kidney disease.
Platelet counts in patients with autosomal dominant polycystic kidney disease (ADPKD) have been reported to be lower than in control populations in one small study but data are sparse. We retrospectively audited real world platelet data from 290 ADPKD patients with corresponding age and sex-matched controls. We analysed 42,972 individual blood counts and patients with ADPKD had statistically lower platelet counts (213 ± 63 vs. 238 ± 69 × 10(9)/L, p < 0.01) on dialysis. In the transplant and chronic kidney disease (CKD) groups, there were no significant differences in the platelet counts. The magnitude of the difference in platelet numbers was small and unlikely to be clinically significant, so findings of low platelets in ADPKD should be further investigated.
['Setyapranata|Stella|S|', 'Holt|Stephen G|SG|']
D000328:Adult D000368:Aged D015415:Biomarkers D005260:Female D006801:Humans D008297:Male D008875:Middle Aged D010976:Platelet Count D016891:Polycystic Kidney, Autosomal Dominant D006435:Renal Dialysis D012189:Retrospective Studies
platelets polycystic kidney dialysis Cystic kidney disease