Obesity and vitamin D deficiency: a systematic review and meta-analysis.
Over the past decade, there have been an increasing number of studies on the association between vitamin D deficiency and anthropometric state. However, we did not identify any meta-analyses of the relationship between obesity and vitamin D deficiency in different age groups. Thus, we evaluated the association between obesity and vitamin D deficiency. We searched for observational studies published up to April 2014 in PubMed/Medline, Web of Science and Scopus databases. We performed a meta-analysis in accordance with the random-effects model to obtain the summary measurement (prevalence ratio, PR). Among the 29,882 articles identified, 23 met the inclusion criteria. The prevalence of vitamin D deficiency was 35% higher in obese subjects compared to the eutrophic group (PR: 1.35; 95% CI: 1.21-1.50) and 24% higher than in the overweight group (PR: 1.24; 95% CI: 1.14-1.34). These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.
['Pereira-Santos|M|M|', 'Costa|P R F|PR|', 'Assis|A M O|AM|', 'Santos|C A S T|CA|', 'Santos|D B|DB|']
D017677:Age Distribution D006801:Humans D009765:Obesity D015995:Prevalence D014807:Vitamin D D014808:Vitamin D Deficiency
obesity vitamin D deficiency meta-analysis 25-hydroxy vitamin D