Use of contrast-enhanced ultrasound in evaluating the efficacy and application value of microwave ablation for adenomyosis.
Aim
This study aims to assess the use of contrast-enhanced ultrasonography (CEUS) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the evaluation of percutaneous microwave ablation (PMWA) of localized adenomyosis.


Materials and Methods
Sixty-six patients with single-onset adenomyosis who underwent PMWA at the Liaocheng Tumor Hospital of Shandong Province from January 2013 to February 2019 were enrolled. Venous CEUS and DCE-MRI examinations were performed before and 1-2 days after the surgery. The ablation rates calculated by CEUS and DCE-MRI were compared and analyzed for accuracy.


Results
After microwave ablation (MWA), CEUS showed that the volume and ablation rate of the ablated zone were 52.03 ± 28.39 cm3 and 90.90% ±6.61%, respectively. By DCE-MRI, the ablation volume and ablation rate of adenomyosis were 52.20 ± 28.65 cm3 and 90.88% ±6.32%, respectively. Dysmenorrhea was significantly relieved within 3 months of the operation, and nonmenstrual hemoglobin levels were significantly improved at 3 and 6 months after the operation (P < 0.05). All 66 cases of adenomyosis were treated using PMWA. Postoperatively, 17 patients reported a change in vaginal fluid; however, no special treatment was required as this disappeared 2-11 days after surgery.


Conclusions
CEUS can accurately evaluate the ablation rate of localized adenomyosis treated with MWA, which is consistent with DCE-MRI. It is convenient and easy to perform ablation of adenomyomas, with incomplete ablation and angiography, and is a method worthy of clinical promotion.
['Xu|Chao|C|', 'Tang|Yanyan|Y|', 'Zhao|Yingying|Y|', 'Li|Yongjie|Y|', 'Feng|Qingliang|Q|']
D062788:Adenomyosis D000328:Adult D017115:Catheter Ablation D003287:Contrast Media D005260:Female D005500:Follow-Up Studies D006801:Humans D008279:Magnetic Resonance Imaging D008872:Microwaves D008875:Middle Aged D012189:Retrospective Studies D016896:Treatment Outcome D014463:Ultrasonography
ultrasound microwave ablation Adenomyosis magnetic resonance imaging contrast agent