Saliva-based PCR tests for SARS-CoV-2 detection.
The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Nasopharyngeal swabs are widely used in polymerase chain reaction (PCR) test to detect SARS-CoV-2. However, the collection of nasopharyngeal swabs has a series of drawbacks concerning exposure of healthcare staff, difficulty in collection, and discomfort of patients. Therefore, an alternative noninvasive sample for diagnostic of emerging viral diseases is required. The usefulness of saliva screening tests is compared to conventional swab tests in this report. The results suggest that saliva could be a reliable sample for detecting SARS-CoV-2.
['Takeuchi|Yoshimasa|Y|', 'Furuchi|Mika|M|', 'Kamimoto|Atsushi|A|', 'Honda|Kazuya|K|', 'Matsumura|Hideo|H|', 'Kobayashi|Ryutaro|R|']
D000073640:Betacoronavirus D000086382:COVID-19 D019411:Clinical Laboratory Techniques D018352:Coronavirus Infections D006801:Humans D058873:Pandemics D011024:Pneumonia, Viral D016133:Polymerase Chain Reaction D045473:SARS Virus D000086402:SARS-CoV-2 D012463:Saliva
PCR SARS-CoV-2 coronavirus COVID-19 saliva