Chemical constituents of hybrids of Ligularia cyathiceps and L. lamarum/L. subspicata collected in China: Structures of subspicatins M, N, O1, and O2, and related compounds.
Three natural hybrids and an introgressed individual of Ligularia were evaluated based on a combination of morphology, root chemicals, and nucleotide sequences of evolutionally neutral regions to understand the chemical outcomes of hybridization and introgression. Six previously undescribed eremophilane sesquiterpenes were isolated from hybrids between L. cyathiceps and L. lamarum/L. subspicata, and benzofurans were isolated from L. subspicata for the first time. Their structures were elucidated based on spectroscopic analyses. Some compounds produced by hybrids have not been detected in either parental species, indicating that the metabolic profile was altered by hybridization and introgression.
['Saito|Yoshinori|Y|', 'Ichihara|Mayu|M|', 'Takashima|Yuriko|Y|', 'Okamoto|Yasuko|Y|', 'Gong|Xun|X|', 'Hanai|Ryo|R|', 'Kuroda|Chiaki|C|', 'Tori|Motoo|M|']
D019659:Asteraceae D001483:Base Sequence D001572:Benzofurans D002681:China D018744:DNA, Plant D006824:Hybridization, Genetic D055442:Metabolome D015394:Molecular Structure D018517:Plant Roots D012717:Sesquiterpenes
Ligularia cyathiceps Subspicatin Eremophilane Asteraceae Chemical diversity Internal transcribed spacer (ITS) Ligularia lamarum Ligularia subspicata Structure elucidation Subspicatol