Relationships between metabolic syndrome and aspects of abdominal aortic aneurysm.
BACKGROUND
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities strongly associated with risks of cardiovascular diseases. However, a relationship between MetS and aneurysmal disease as compared with occlusive disease has not been confirmed. Therefore, correlations of MetS and abdominal aortic aneurysm (AAA) were evaluated.


METHODS
Between March 2011 and February 2020, 354 patients diagnosed with AAA were enrolled and divided into the MetS (n = 164) and the no-MetS (n = 190) groups. Individual components of MetS, characteristics of AAA, rupture rate, and survival rate were evaluated for both groups. Additionally, correlations between MetS and AAA were evaluated with focusing on effects of diabetes mellitus (DM).


RESULTS
The size of AAA was significantly larger in the MetS group compared with the no-MetS group (P < 0.05). The rupture rate was significantly higher in the MetS group compared with the no-MetS group (P < 0.05) and the survival rate was significantly higher in the no-MetS group (P < 0.05). In terms of DM, the size of AAA was significantly larger in the no-DM group compared with the DM group (P < 0.05). MetS was significantly more prevalent in the DM group compared with the no-DM group (P < 0.05). Finally, the rupture and survival rates were not statistically different between the DM and the no-DM groups (P > 0.05).


CONCLUSIONS
Although larger prospective studies are necessary, we suggest that MetS proportionally aggravates the status of AAA and survival rate. Therefore, surveillance for MetS and individual components may help to restrict the expansion of AAA.
['Lee|Jong Seok|JS|', 'Park|Sun Cheol|SC|', 'Kim|Sang Dong|SD|']
Metabolic syndrome Abdominal aortic aneurysm Diabetes mellitus