Early versus late surgery of thoracic spine fractures in multiple injured patients: is early stabilization always recommendable?
BACKGROUND CONTEXT
Many institutions' retrospective studies investigated the effect of the timing of surgery on outcomes of polytraumatized patients with severe lesions of the thoracic spine and mainly found a better outcome for patients who were operated on less than 72 hours posttrauma.


PURPOSE
We conducted a prospective study in a Level I trauma center to validate the retrospective data and to investigate other variables, in addition to the timing of surgery that may influence patient outcomes.


STUDY DESIGN
Prospective observational clinical study.


PATIENT SAMPLE
Within this prospective study at a Level I trauma center, we enrolled 38 multiple injured patients with unstable fractures of vertebral column from Level Th1 to L1. Further inclusion criteria consisted of an injury severity score of 16 or more and an intensive care unit (ICU) stay of more than 7 days. The age of included patients was limited from 16 or more to 75 or less years.


OUTCOME MEASURES
Hospital stay, stay on ICU, and mortality.


METHODS
Twenty-two patients were operated on less than or equal to 72 hours posttrauma, and 16 received late surgery greater than or equal to 72 hours posttrauma.


RESULTS
Patients who received early surgery had a significantly higher mortality rate (p<.01) than those who received late surgery. Sixty-seven percent of our patients who had an initial hemoglobin (Hb) less than 10 mg/dL died. Seventy-five percent of those patients who had an Hb less than 10 mg/dL and received a thoracic drain died.


CONCLUSIONS
Although some reports indicate advantages for early surgery for thoracic spine trauma in the polytraumatized patient, careful patient selection should be used. Based on the results of this prospective study, early surgery for thoracic spine trauma in patients with concomitant severe thoracic trauma and low initial Hb levels may pose a risk for poor clinical outcomes.
['Konieczny|Markus R|MR|', 'Strüwer|Johannes|J|', 'Jettkant|Birger|B|', 'Schinkel|Christian|C|', 'Kälicke|Thomas|T|', 'Muhr|Gert|G|', 'Frangen|Thomas M|TM|']
D000293:Adolescent D000328:Adult D000368:Aged D005260:Female D006801:Humans D015601:Injury Severity Score D007362:Intensive Care Units D007902:Length of Stay D008297:Male D008875:Middle Aged D011379:Prognosis D011446:Prospective Studies D012189:Retrospective Studies D016103:Spinal Fractures D013904:Thoracic Vertebrae D013997:Time Factors D014193:Trauma Centers D055815:Young Adult
Thoracic spine fracture Timing of surgery Thoracic trauma Polytrauma Second hit