The Effect of Computed Tomography-Guided 125I Radioactive Particle Implantation in Treating Cancer and Its Pain.
BACKGROUND AND AIM
Pain is a prevalent and serious problem in patients with cancer. This study aimed to investigate the clinical value of the implantation of radioactive particle 125I in treating cancer and its pain.


MATERIALS AND METHODS
From February 2014 to February 2015, 38 patients with malignant tumor received computed tomography (CT)-guided 125I radioactive particle implantation to treat cancer pain in this hospital. Before surgery, the lesions were calculated by brachytherapy treatment planning system (TPS) to get the local number of particles that are required for implantation. For a period after implantation, TPS was used again to assess the effect of treatment. The 38 patients received 6-month follow-up, and the CT scan was used to evaluate the local tumor. The visual analogue scale (VAS) was used to assess the pain.


RESULTS
The curative effect was evaluated at postoperative 2, 4, and 6 months, and the curative effect was 34.2%, 73.68%, and 89.47%, respectively. The preoperative VAS score of the 38 patients was 5.48 ± 2.50 (13 cases of mild pain, 19 cases of moderate pain, and 6 cases of severe pain), and their pain was improved in different degrees after operation.


CONCLUSIONS
CT-guided 125I radioactive particle implantation is a safe and effective treatment for cancer and its pain.
['Lu|Wei|W|', 'Du|Peng|P|', 'Yang|Chao|C|', 'Jiang|Fuqiang|F|', 'Xie|Peng|P|', 'Yang|Jian|J|', 'Zhang|Zhe|Z|', 'Ma|Junpeng|J|']
D000328:Adult D000368:Aged D001918:Brachytherapy D005260:Female D006801:Humans D007457:Iodine Radioisotopes D008297:Male D008875:Middle Aged D009366:Neoplasm Seeding D009369:Neoplasms D010146:Pain D010147:Pain Measurement D061089:Radiotherapy, Image-Guided D014057:Tomography, X-Ray Computed D016896:Treatment Outcome
125I radioactive particle cancer pain brachytherapy implantation treatment