Survival and predictors of deaths of patients hospitalised due to COVID-19 from a retrospective and multicentre cohort study in Brazil.
This study aimed to analyse the survival of patients admitted to Brazilian hospitals due to the COVID-19 and estimate prognostic factors. This is a retrospective, multicentre cohort study, based on data from 46 285 hospitalisations for COVID-19 in Brazil. Survival functions were calculated using the Kaplan-Meier's method. The log-rank test compared the survival functions for each variable and from that, hazard ratios (HRs) were calculated, and the proportional hazard model was used in Cox multiple regression. The smallest survival curves were the ones for patients at the age of 68 years or more, black/mixed race, illiterate, living in the countryside, dyspnoea, respiratory distress, influenza-like outbreak, O2 saturation <95%, X-ray change, length of stay in the intensive care unit (ICU), invasive ventilatory support, previous heart disease, pneumopathy, diabetes, Down's syndrome, neurological disease and kidney disease. Better survival was observed in the influenza-like outbreak and in an asthmatic patient. The multiple model for increased risk of death when they were admitted to the ICU HR 1.28, diabetes HR 1.17, neurological disease HR 1.34, kidney disease HR 1.11, heart disease HR 1.14, black or mixed race of HR 1.50, asthma HR 0.71 and pneumopathy HR 1.12. This reinforces the importance of socio-demographic and clinical factors as a prognosis for death.
['Santos|M M|MM|0000-0001-5812-4004', 'Lucena|E E S|EES|0000-0003-3119-7822', 'Lima|K C|KC|0000-0002-5668-4398', 'Brito|A A C|AAC|', 'Bay|M B|MB|0000-0002-5569-1756', 'Bonfada|D|D|0000-0001-9725-9446']
D000368:Aged D000073640:Betacoronavirus D001938:Brazil D000086382:COVID-19 D015331:Cohort Studies D018352:Coronavirus Infections D005260:Female D017052:Hospital Mortality D006801:Humans D008297:Male D008875:Middle Aged D058873:Pandemics D011024:Pneumonia, Viral D016016:Proportional Hazards Models D012189:Retrospective Studies D012307:Risk Factors D000086402:SARS-CoV-2
hospitalisations Coronavirus infections SARS virus risk factors survival analysis