Detection of Risk Groups for Carcinogenic Liver Fluke Infection by Verbal Screening Questionnaire Using a Mobile Application
The carcinogenic liver fluke, Opisthorchis viverrini, is a serious health problem in Southeast Asia where infection
is associated with cholangiocarcinoma, a major cause of death in Thailand. This cross-sectional study aimed to screen
for O. viverrini infection among a Thai rural population of 560 individuals from Nakhon Ratchasima, Khonkaen, and
Chaiyaphum provinces with a verbal screening test with a mobile application (OvApp). Faecal samples were also
processed with a mini-parasep sf parasite faecal concentrator. The infection rate of O. viverrini was found to be 2.86%.
The majority of infections were detected in males aged 41–50, with primary school being their highest education level, and
who were engaged in agricultural occupations. In screening for O. viverrini infection, the OvApp had a high sensitivity
(87.5%), specificity (94.6%), negative predictive value (98.9%), and accuracy (98.6%). The positive predictive value
was 70.0% for the OvApp. The observed agreement was substantial for this application (k-value = 0.64) indicated that
it is a potentially useful tool for decreasing the cost of large-scale O. viverrini screening.
['Kaewpitoon|Natthawut|N|', 'Kaewpitoon|Soraya J|SJ|', 'Meererksom|Thirayu|T|', 'Chan-Aran|Siwawich|S|', 'Sangwalee|Wararat|W|', 'Kujapun|Jirawoot|J|', 'Norkaew|Jun|J|', 'Chuatanam|Jirayut|J|', 'Ponpimai|Sukanya|S|', 'Pothipim|Mali|M|', 'Padchasuwan|Natnapa|N|', 'Tongtawee|Taweesak|T|', 'Matrakool|Likit|L|', 'Panpimanmas|Sukij|S|', 'Loyd|Ryan A|RA|', 'Wakkhuwatthapong|Parichart|P|']
D000328:Adult D000818:Animals D001650:Bile Duct Neoplasms D018281:Cholangiocarcinoma D003430:Cross-Sectional Studies D005243:Feces D005260:Female D005500:Follow-Up Studies D006801:Humans D008107:Liver Diseases D008297:Male D008875:Middle Aged D063731:Mobile Applications D009889:Opisthorchiasis D009891:Opisthorchis D011379:Prognosis D011795:Surveys and Questionnaires D013785:Thailand
verbal screening questionnaire Opisthorchis viverrini Thailand mobile application OvApp