Fabrication a controlled-release pesticide for improving UV-shielding properties and reducing toxicity via coating polydopamine.
Controlled-release formulations (CRFs) have potential applications in modern agriculture, for it can not only prolong the duration of agrochemicals but also alleviate the adverse effect on non-target organism. In this study, we constructed pyraclostrobin@SiO2@polydopamine microcapsule (Pyr@SiO2@PDA MC). The resulting microcapsule is a near-rod shape (about 1.15 μm), which has a drug-loading efficiency of 55%. Fourier transform infrared (FTIR) and thermogravimetric analysis (TG) revealed the successful entrapment of the pesticide. The coating of polydopamine (PDA) endowing the microcapsule with superior UV-shielding properties than pyraclostrobin@SiO2 microcapsule (Pyr@SiO2 MC). Compared with pyraclostrobin emulsifiable concentrate (EC), the Pyr@SiO2@PDA MC exhibited 9.07-, 5.50-, 4.93- and 4.16-fold higher fungicidal activity against Rice blast fungus (Pyricularia oryzae) at concentrations of 0.5, 1, 2 and 4 mg/L. Moreover, acute toxicity tests demonstrated that the sample on zebrafish with lower toxicity on the first day. These results showed that the obtained microcapsule may process broader application potential in agriculture.
['Wang|Ya|Y|', 'Li|Chaonan|C|', 'Zhang|Xin|X|', 'Chen|Wei|W|', 'Li|Xiaogang|X|']
D000818:Animals D001203:Ascomycota D002214:Capsules D003692:Delayed-Action Preparations D007211:Indoles D010575:Pesticides D011108:Polymers D012822:Silicon Dioxide D000073739:Strobilurins D023382:Toxicity Tests, Acute D014874:Water Pollutants, Chemical D015027:Zebrafish
polydopamine Pyraclostrobin acute toxicity evaluation bioactivity sustained release