Biomedical application and controlled drug release of electrospun fibrous materials.
Electrospinning, as a nanotechnology, is able to produce polymeric fibers materials with nanoscale structure which are also named electrospun fibers material (EFM). These EFMs can be used in many biomedical applications such as wound dressing, tissue engineering, and medical textile materials. Over the last decades, electrospun nanofibers also have been applied to drug delivery such as orodispersible film, solid dispersion and various controlled release dosage forms due to many properties such as high surface to volume ratio, high porous, ease of fabrication and adaptability and so on. This review focuses on the recent advances in biomedical application of EFM, controlled drug release from EFM and devices for producing sophisticated EFM. The processing parameters which influence the physicochemical properties of the resulting EFM are also summarized as well as scaling up techniques for mass production of EFM.
['Cheng|Huiling|H|', 'Yang|Xiaoye|X|', 'Che|Xin|X|', 'Yang|Mingshi|M|', 'Zhai|Guangxi|G|']
D001672:Biocompatible Materials D003692:Delayed-Action Preparations D016503:Drug Delivery Systems D065546:Drug Liberation D057139:Nanofibers D011108:Polymers D023822:Tissue Engineering
Biomedical application Controlled drug release Electrospinning Membranes Scaffolds