As might have been expected, his Orthodox opponents had him arrested in Russia and exiled to Siberia, where he died in 1735.
Kā jau bija gaidāms, Serafima pretinieki no pareizticīgo baznīcas panāca, ka viņš Krievijā tiek arestēts un izsūtīts uz Sibīriju, kur 1735. gadā viņš nomira.