The first farmer who bred his best bull with the best cow in his herd to improve the stock, instead of allowing the animals to breed randomly, was implementing biotechnology in a rudimentary sense.
Pirmais lopkopis, kas sakrustoja savu labāko bulli ar labāko govi, lai uzlabotu savu ganāmpulku, nevis ļāva dzīvniekiem krustoties pēc nejaušības principa, būtībā izmantoja pavisam primitīvu biotehnoloģiju.