From as early as the 15th century, Uzbekistan’s cities were useful to merchants traveling on the Silk Road, a network of roads that once connected China to the Mediterranean.
Sejak awal abad ke - 15, kota - kota Uzbekistan sangat berguna bagi para pedagang yang melintasi Jalur Sutra, serangkaian jalan yang dulunya menghubungkan Cina ke kawasan Laut Tengah.