In that case, “the coming wrath ” was centered on one particular locale, Jerusalem and Judea, so it could have been possible to flee in a literal way.
٥ كَيْفَ أَثْبَتَ ٱلتَّارِيخُ صِحَّةَ ٱلتَّحْذِيرَيْنِ ٱللَّذَيْنِ وَجَّهَهُمَا يُوحَنَّا وَيَسُوعُ ؟‏