To let the figurative hands drop down has at times been used to describe someone who is discouraged, disheartened, or without hope. It is common for a person in that situation to give up.
أَمَّا حِينَ تَذْكُرُ كَلِمَةُ ٱللهِ أَنَّ ‹ ٱلْيَدَ ٱرْتَخَتْ › ،‏ فَتُشِيرُ أَنَّ ٱلشَّخْصَ مُثَبَّطٌ ،‏ مُكْتَئِبٌ ،‏ أَوْ يَائِسٌ .‏