After resigning ecclesiastical office, he wed a French princess, thus obtaining the duchy of Valentinois. Then, with the support of French troops, he began a campaign of siege and assassination to bring the north of Italy under his control.
पोप सहसा टीका करणाऱ्‍यांकडे दुर्लक्ष करत असे परंतु टीका करणाऱ्‍या एका व्यक्‍तीकडे मात्र दुर्लक्ष करता आले नाही; ती व्यक्‍ती होती गिरोलामो सॅव्होनारोला.