<sod>All oogonial stem cells in ''C. elegans'' are derived from one Distal Tip Cell (DTC) which acts as niche to ensure that germline proliferation continues. As the DTC undergoes mitosis, the cells move proximally along the organism, passing from the “mitotic/proliferative region” into the meiotic cycle. During the meiotic cycle the cells complete meiotic prophase before passing into the zone of oogenesis/spermatogenesis depending on the sex and age of the organism (Fig 1).<ref name=":0" /><ref name=":1" /><ref>{{Cite journal|last=Cinquin|first=Olivier|last2=Crittenden|first2=Sarah L.|last3=Morgan|first3=Dyan E.|last4=Kimble|first4=Judith|date=2010-02-02|title=Progression from a stem cell–like state to early differentiation in the C. elegans germ line|url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836686/|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=107|issue=5|pages=2048–2053|doi=10.1073/pnas.0912704107|issn=0027-8424|pmc=2836686|pmid=20080700}}</ref><eod>
<sod>All oogonial stem cells in ''C. elegans'' are derived from one Distal Tip Cell (DTC) which acts as niche to ensure that germline proliferation continues. As the DTC undergoes mitosis, the cells move proximally along the organism, passing from the "mitotic/proliferative region" into the meiotic cycle. During the meiotic cycle the cells complete meiotic prophase before passing into the zone of oogenesis/spermatogenesis depending on the sex and age of the organism (Fig 1).<ref name=":0" /><ref name=":1" /><ref>{{Cite journal|last=Cinquin|first=Olivier|last2=Crittenden|first2=Sarah L.|last3=Morgan|first3=Dyan E.|last4=Kimble|first4=Judith|date=2010-02-02|title=Progression from a stem cell–like state to early differentiation in the C. elegans germ line|url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836686/|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=107|issue=5|pages=2048–2053|doi=10.1073/pnas.0912704107|issn=0027-8424|pmc=2836686|pmid=20080700}}</ref><eod>