<sod>The [[symptoms]] of Addison's disease develop gradually and may become established before they are recognized. The signs and symptoms readily mimic many other ailments and include<ref>Tamparo, Carol D., 1940- Diseases of the human body/ Carol D. Tamparo, Marcia A. Lewis.-- 5th ed. Pg 299</ref>[[fatigue (medical)|fatigue]]; [[Syncope (medicine)|lightheadedness]] upon standing or difficulty standing; [[muscle weakness]]; [[fever]]; [[weight loss]]; [[anxiety]]; [[nausea]]; [[vomiting]]; [[diarrhea]]; [[headache]]; [[sweating]]; changes in [[Mood (psychology)|mood]] or [[personality psychology|personality]]; and [[arthralgia|joint]] and [[myalgia|muscle pains]]. Some patients have [[Food craving|cravings]] for [[Sodium chloride|salt]] or salty foods due to the loss of sodium through their [[urine]].<ref name=Ten/>  [[Hyperpigmentation]] of the skin may be seen, particularly when the patient lives in a sunny area, as well as darkening of the [[palmar crease]], sites of friction, recent scars, the [[vermilion border]] of the lips, and genital skin.<ref>{{cite journal | author = Nieman LK, Chanco Turner ML | title = Addison's disease | journal = [[Clinics in Dermatology]] | volume = 24 | issue = 4 | pages = 276–280 | year = 2006 | pmid = 16828409 | doi = 10.1016/j.clindermatol.2006.04.006 }}</ref> These skin changes are not encountered in secondary and tertiary hypoadrenalism.<ref name=AdrenalCrisis>{{cite journal | author = de Herder WW, van der Lely AJ | title = Addisonian crisis and relative adrenal failure | journal = Reviews in Endocrine and Metabolic Disorders | volume = 4 | issue = 2 | pages = 143–7 | date = May 2003 | pmid = 12766542 | doi = 10.1023/A:1022938019091 }}</ref><eod>
<sod>The [[symptoms]] of Addison's disease develop gradually and may become established before they are recognized. The signs and symptoms include [[fatigue (medical)|fatigue]]; [[Syncope (medicine)|lightheadedness]] upon standing or difficulty standing; [[muscle weakness]]; [[fever]]; [[weight loss]]; [[anxiety]]; [[nausea]]; [[vomiting]]; [[diarrhea]]; [[headache]]; [[sweating]]; changes in [[Mood (psychology)|mood]] or [[personality psychology|personality]]; and [[arthralgia|joint]] and [[myalgia|muscle pains]]. Some patients have [[Food craving|cravings]] for [[Sodium chloride|salt]] or salty foods due to the loss of sodium through their [[urine]].<ref name=Ten/>  [[Hyperpigmentation]] of the skin may be seen, particularly when the patient lives in a sunny area, as well as darkening of the [[palmar crease]], sites of friction, recent scars, the [[vermilion border]] of the lips, and genital skin.<ref>{{cite journal | author = Nieman LK, Chanco Turner ML | title = Addison's disease | journal = [[Clinics in Dermatology]] | volume = 24 | issue = 4 | pages = 276–280 | year = 2006 | pmid = 16828409 | doi = 10.1016/j.clindermatol.2006.04.006 }}</ref> These skin changes are not encountered in secondary and tertiary hypoadrenalism.<ref name=AdrenalCrisis>{{cite journal | author = de Herder WW, van der Lely AJ | title = Addisonian crisis and relative adrenal failure | journal = Reviews in Endocrine and Metabolic Disorders | volume = 4 | issue = 2 | pages = 143–7 | date = May 2003 | pmid = 12766542 | doi = 10.1023/A:1022938019091 }}</ref><eod>