<sod>The synthesis of iodoform was first described by Georges Serrulas in 1822, by reactions of iodine vapour with steam over red hot coals, and also by reaction of potassium with ethanolic iodine in the presence of water;<ref>{{citation| first = Georges-Simon|last = Surellas| url = http://gallica.bnf.fr/ark:/12148/bpt6k6137757n/f2.image |title = Notes sur l'Hydriodate de potasse et l'Acide hydriodique. -- Hydriodure de carbone; moyen d'obtenir, à l'instant, ce composé triple|trans-title= Notes on the hydroiodide of potassium and on hydroiodic acid -- hydroiodide of carbon; means of obtaining instantly this compound of three elements| language = French| publisher = Metz, France: Antoine| year= 1822|  pages= 17-20, 28-29}}</ref> and at much the same time independently by [[John Thomas Cooper]].<ref name=ODNB>{{cite web|last=James|first=Frank A. J. L.|title=Cooper, John Thomas (1790–1854), chemist|url=http://www.oxforddnb.com/view/article/39361|work=Oxford Dictionary of National Biography|publisher=Oxford University Press|accessdate=26 January 2012}}</ref> It is synthesized in the [[haloform reaction]] by the reaction of iodine and sodium hydroxide with any one of these four kinds of organic compounds: (i) a methyl [[ketone]]: CH<sub>3</sub>COR, [[acetaldehyde]] (CH<sub>3</sub>CHO), [[ethanol]] (CH<sub>3</sub>CH<sub>2</sub>OH), and certain secondary [[alcohol]]s (CH<sub>3</sub>CHROH, where R is an alkyl or aryl group).<eod>
<sod>The synthesis of iodoform was first described by [[Georges-Simon Serullas]] in 1822, by reactions of iodine vapour with steam over red hot coals, and also by reaction of potassium with ethanolic iodine in the presence of water;<ref>{{citation| first = Georges-Simon|last = Surellas| url = http://gallica.bnf.fr/ark:/12148/bpt6k6137757n/f2.image |title = Notes sur l'Hydriodate de potasse et l'Acide hydriodique. -- Hydriodure de carbone; moyen d'obtenir, à l'instant, ce composé triple|trans-title= Notes on the hydroiodide of potassium and on hydroiodic acid -- hydroiodide of carbon; means of obtaining instantly this compound of three elements| language = French| publisher = Metz, France: Antoine| year= 1822|  pages= 17-20, 28-29}}</ref> and at much the same time independently by [[John Thomas Cooper]].<ref name=ODNB>{{cite web|last=James|first=Frank A. J. L.|title=Cooper, John Thomas (1790–1854), chemist|url=http://www.oxforddnb.com/view/article/39361|work=Oxford Dictionary of National Biography|publisher=Oxford University Press|accessdate=26 January 2012}}</ref> It is synthesized in the [[haloform reaction]] by the reaction of iodine and sodium hydroxide with any one of these four kinds of organic compounds: (i) a methyl [[ketone]]: CH<sub>3</sub>COR, [[acetaldehyde]] (CH<sub>3</sub>CHO), [[ethanol]] (CH<sub>3</sub>CH<sub>2</sub>OH), and certain secondary [[alcohol]]s (CH<sub>3</sub>CHROH, where R is an alkyl or aryl group).<eod>