This natural selection process is exacerbated by human factors such as inappropriate use of antimicrobials in human and veterinary medicine, poor hygiene conditions and practices in healthcare settings or in the food chain facilitating the transmission of resistant microorganisms.
Seda loodusliku valiku protsessi soodustab inimtegevus, nt antimikroobikumide väärkasutus inim- ja veterinaartervishoius ning resistentsete mikroorganismide levikut hõlbustavad halvad hügieenitingimused ja halb hügieenitava tervishoiuasutustes või toidutarneahelas.