Plasma and plasma derivatives can have a longer shelf-life and as fractionation plants exist only in twelve Member States, both plasma (the starting material) and plasma derivatives (the end product) are frequently exchanged across borders, within the EU and with third (non-EU) countries.
Plazma i derivati plazme mogu imati dulji rok upotrebe, a s obzirom na to da postrojenja za frakcioniranje postoje u samo 12 država članica, plazma (sirovina) i derivati plazme (krajnji proizvod) često se razmjenjuju preko granica, unutar EU-a i s trećim zemljama (koje nisu članice EU-a).