Splitting tablets: benefits and risks
The definition of mass homogeneity for the four kinds of pills and their parts (after dividing into two or four parts) was held. The necessity of standardiza- tion of the possibility of solid dosage forms splitting by making suitable section in the instructions to the drug and the development of mass homogeneity quality control methods of individual parts, as well as the ease of division and mass loss in the fission of solid dosage forms is shown.