Likely due to effects of COMPOUND_XXX on fast renewal cells division cycle by Met receptor tyrosine kinase inhibition and associated changes : - disorganisations of the intestinal epithelium and / or the increase in the apoptotic bodies number were noted in both sexes at 40 mg / kg only with a severity and incidence more marked in dosed - females .
Likely due to effects of COMPOUND_XXX on fast renewal cells division cycle by Met receptor tyrosine kinase inhibition and associated changes : - disorganisations of the intestinal epithelium and / or the increase in the apoptotic bodies number were noted in both sexes at 40 mg / kg only with a severity and incidence more marked in dosed - females .
O O O O O O O O O O O O O O O O O O O O O O O B-FINDING O O B-SPECIMEN I-SPECIMEN O O O O B-MANIFESTATION_FINDING O O B-FINDING I-FINDING O O O O B-SEX I-SEX O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O