Following once weekly dosing with COMPOUND_XXX for 13 weeks at 3.0 mg / kg , the AUC for COMPOUND_XXX was 1000 ng · hr / mL for males and 660 ng hr / mL for females and the Cmax was 746 ng / mL for males and 493 ng / mL for females ; for metabolite YYYYY the AUC was 298 ng · hr / mL for males and 178 ng · hr / mL for females and the Cmax was 79.2 mg / mL for males and 40.7 ng / mL for females .
Following once weekly dosing with COMPOUND_XXX for 13 weeks at 3.0 mg / kg , the AUC for COMPOUND_XXX was 1000 ng · hr / mL for males and 660 ng hr / mL for females and the Cmax was 746 ng / mL for males and 493 ng / mL for females ; for metabolite YYYYY the AUC was 298 ng · hr / mL for males and 178 ng · hr / mL for females and the Cmax was 79.2 mg / mL for males and 40.7 ng / mL for females .
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