For the high dose ( 480 mg / kg / dose ) the decrease was lower ( below 40 % ) .
For the high dose ( 480 mg / kg / dose ) the decrease was lower ( below 40 % ) .
O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O