Microscopic pathology findings observed in the 500 mg / kg / day NS and OS dose groups included , hyperostosis of the metaphysis , growth plate thickening , fibroplasia and / or hyperplasia of the synovial lining cells surrounding the knee / hock joint surfaces .
Microscopic pathology findings observed in the 500 mg / kg / day NS and OS dose groups included , hyperostosis of the metaphysis , growth plate thickening , fibroplasia and / or hyperplasia of the synovial lining cells surrounding the knee / hock joint surfaces .
O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE B-GROUP I-GROUP I-GROUP I-GROUP I-GROUP O O B-FINDING O O B-SPECIMEN O B-FINDING I-FINDING I-FINDING O B-FINDING O O O B-FINDING O O B-SPECIMEN I-SPECIMEN I-SPECIMEN O O B-SPECIMEN O B-SPECIMEN B-SPECIMEN O O