In the spleen , hemopoiesis , which is usually present to variable extents in untreated rats , was reduced or absent at 180 mg / kg at all necropsy time points .
In the spleen , hemopoiesis , which is usually present to variable extents in untreated rats , was reduced or absent at 180 mg / kg at all necropsy time points .
O O B-SPECIMEN O B-FINDING O O O O O O O O O O O O O B-MANIFESTATION_FINDING I-MANIFESTATION_FINDING I-MANIFESTATION_FINDING O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O