No specific target organ toxicity has been observed , although typical signs of excessive cholinergic stimulation occur at high doses in the gastrointestinal tract and central nervous system .
No specific target organ toxicity has been observed , although typical signs of excessive cholinergic stimulation occur at high doses in the gastrointestinal tract and central nervous system .
O O O O O O O O O O O B-FINDING I-FINDING I-FINDING I-FINDING I-FINDING O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O O B-SPECIMEN I-SPECIMEN O B-SPECIMEN I-SPECIMEN I-SPECIMEN O