In general , overall exposure to COMPOUND_XXX in terms of AUC ( 0 - 21h ) values was much higher than to its metabolite PAG by a factor of 10 in plasma ( only high dose ) , of 14 or 31 in jejunal mucosa and of about 300 in jejunal content .
In general , overall exposure to COMPOUND_XXX in terms of AUC ( 0 - 21h ) values was much higher than to its metabolite PAG by a factor of 10 in plasma ( only high dose ) , of 14 or 31 in jejunal mucosa and of about 300 in jejunal content .
O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O O O O O O O O O O O O O O O O O