Thereafter , minimal decreases in mean body weight ( 3 - 6 % ) were apparent in both sexes at doses of 30 and 100 mg / kg / day and in females at 300 mg / kg / day by the end of dosing .
Thereafter , minimal decreases in mean body weight ( 3 - 6 % ) were apparent in both sexes at doses of 30 and 100 mg / kg / day and in females at 300 mg / kg / day by the end of dosing .
O O O B-MANIFESTATION_FINDING O O B-STUDY_TESTCD I-STUDY_TESTCD O O O O O O O O O B-SEX I-SEX O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O O O