Minimal increases in aPTT in males and females at 1.5 mg / kg , decreases in cholesterol in females at 1.5 mg / kg , and increases in creatinine in males and females at doses ≥ 0.5 mg / kg were considered not to be of any toxicologic significance .
Minimal increases in aPTT in males and females at 1.5 mg / kg , decreases in cholesterol in females at 1.5 mg / kg , and increases in creatinine in males and females at doses ≥ 0.5 mg / kg were considered not to be of any toxicologic significance .
O B-MANIFESTATION_FINDING O B-STUDY_TESTCD O B-SEX I-SEX I-SEX O B-DOSE I-DOSE I-DOSE I-DOSE O B-MANIFESTATION_FINDING O B-STUDY_TESTCD O B-SEX O B-DOSE I-DOSE I-DOSE I-DOSE O O B-MANIFESTATION_FINDING O B-STUDY_TESTCD O B-SEX I-SEX I-SEX O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O