Compound - related organ weight ( absolute and covariant ) decreases were present at doses ≥ 10 mg / kg and included decreases in submaxillary salivary gland weights ( doses ≥ 10 mg / kg in males ; doses ≥ 30 mg / kg in females ) , adrenal ( doses ≥ 30 mg / kg in males and females ) , liver weights ( doses ≥ 30 mg / kg in males and 75 mg / kg in females ) and prostate weights ( males at ≥ 10 mg / kg ) .
Compound - related organ weight ( absolute and covariant ) decreases were present at doses ≥ 10 mg / kg and included decreases in submaxillary salivary gland weights ( doses ≥ 10 mg / kg in males ; doses ≥ 30 mg / kg in females ) , adrenal ( doses ≥ 30 mg / kg in males and females ) , liver weights ( doses ≥ 30 mg / kg in males and 75 mg / kg in females ) and prostate weights ( males at ≥ 10 mg / kg ) .
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