In the femoral or tibial bone , dose dependent decreases in mature lamellar bone and trabecular bone were noted at 25 mg / kg and higher after 14 weeks of dosing , and were comparable to those after 26 weeks of dosing .
In the femoral or tibial bone , dose dependent decreases in mature lamellar bone and trabecular bone were noted at 25 mg / kg and higher after 14 weeks of dosing , and were comparable to those after 26 weeks of dosing .
O O B-SPECIMEN O B-SPECIMEN I-SPECIMEN O O O B-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING I-FINDING O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O O O O O O O