At the end of the dosing period , at 1.0 mg / kg , the mean AUC ( 0 - 24h ) was 71.2 ± 37.3 ng.h / mL and 91.8 ± 37.6 ng.h / mL for males and females respectively , Cmax , was 16.0 ± 9.20 ng / mL and 24.2 ± 13.7 ng / mL for males and females respectively and tmax , was 0.750 ± 0.289 h and 0.625 ± 0.250 h for males and females respectively .
At the end of the dosing period , at 1.0 mg / kg , the mean AUC ( 0 - 24h ) was 71.2 ± 37.3 ng.h / mL and 91.8 ± 37.6 ng.h / mL for males and females respectively , Cmax , was 16.0 ± 9.20 ng / mL and 24.2 ± 13.7 ng / mL for males and females respectively and tmax , was 0.750 ± 0.289 h and 0.625 ± 0.250 h for males and females respectively .
O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O