The pharmacokinetic evaluation of the present study indicates an about linear pharmacokinetic behavior of the drug after i.v. administration of 0.01 , 0.07 or 0.5 mg / kg COMPOUND_XXX in female Cynomolgus monkeys , i.e. the increase of systemic exposure and observed maximum concentrations was about proportional to the dose increase .
The pharmacokinetic evaluation of the present study indicates an about linear pharmacokinetic behavior of the drug after i.v. administration of 0.01 , 0.07 or 0.5 mg / kg COMPOUND_XXX in female Cynomolgus monkeys , i.e. the increase of systemic exposure and observed maximum concentrations was about proportional to the dose increase .
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