Slightly decreased thrombin times and / or increased activated thromboplastin times , fibrinogen concentrations , platelet counts and prothrombin times were also observed during treatment at 50 mg / kg / day or above .
Slightly decreased thrombin times and / or increased activated thromboplastin times , fibrinogen concentrations , platelet counts and prothrombin times were also observed during treatment at 50 mg / kg / day or above .
O B-MANIFESTATION_FINDING B-STUDY_TESTCD I-STUDY_TESTCD O O O B-MANIFESTATION_FINDING O B-STUDY_TESTCD I-STUDY_TESTCD O B-STUDY_TESTCD I-STUDY_TESTCD O B-STUDY_TESTCD I-STUDY_TESTCD O B-STUDY_TESTCD I-STUDY_TESTCD O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O