Findings after the high dose of 150/100 mg / kg COMPOUND_XXX are regarded as signs of general toxicity of the compound .
Findings after the high dose of 150/100 mg / kg COMPOUND_XXX are regarded as signs of general toxicity of the compound .
O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE O O O O B-FINDING I-FINDING I-FINDING I-FINDING O O O O