Dose - dependent , fluoride - related changes in the bone and teeth were observed in bone density , bone strength , mineral ash content and trace elements as well as macroscopic and histologic changes after 14 and 26 weeks of administration .
Dose - dependent , fluoride - related changes in the bone and teeth were observed in bone density , bone strength , mineral ash content and trace elements as well as macroscopic and histologic changes after 14 and 26 weeks of administration .
O O O O B-STUDY_TESTCD O O B-MANIFESTATION_FINDING O O B-SPECIMEN O B-SPECIMEN O O O B-SPECIMEN B-STUDY_TESTCD O B-SPECIMEN B-STUDY_TESTCD O B-STUDY_TESTCD I-STUDY_TESTCD I-STUDY_TESTCD O B-STUDY_TESTCD I-STUDY_TESTCD O O O B-FINDING I-FINDING I-FINDING I-FINDING O O O O O O O O