The finding was reversible in the mid dose group but not reversible in the high dose group Additionally at the high dose of 9.0 mg / kg COMPOUND_XXX : e diarrhea , diminished muscular tone , emaciation , ruffled fur and encrusted nose occurred in males and females .
The finding was reversible in the mid dose group but not reversible in the high dose group Additionally at the high dose of 9.0 mg / kg COMPOUND_XXX : e diarrhea , diminished muscular tone , emaciation , ruffled fur and encrusted nose occurred in males and females .
O O O O O O B-GROUP I-GROUP I-GROUP O O O O O B-GROUP I-GROUP I-GROUP O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE O O O B-FINDING O B-FINDING I-FINDING I-FINDING O B-FINDING O B-FINDING I-FINDING O B-FINDING I-FINDING O O B-SEX I-SEX I-SEX O