Eighty ( 80 ) Wistar rats were allocated to 8 groups ( 5 animals / sex / group ) and treated by the dermal route either once daily from Days 1 - 28 or twice weekly from Days 1 - 28 with the control article or the test articles , COMPOUND_XXX 100 mg / g Nail Lacquer ; COMPOUND_XXX 200 mg / g Nail Lacquer ; or COMPOUND_XXX 270 mg / g Nail Lacquer , at dose levels of 100 , 200 , or 270 mg / kg / day .
Eighty ( 80 ) Wistar rats were allocated to 8 groups ( 5 animals / sex / group ) and treated by the dermal route either once daily from Days 1 - 28 or twice weekly from Days 1 - 28 with the control article or the test articles , COMPOUND_XXX 100 mg / g Nail Lacquer ; COMPOUND_XXX 200 mg / g Nail Lacquer ; or COMPOUND_XXX 270 mg / g Nail Lacquer , at dose levels of 100 , 200 , or 270 mg / kg / day .
O O O O O O O O O O O O B-GROUP I-GROUP I-GROUP I-GROUP I-GROUP I-GROUP O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O