The degree of thickening was dose - dependant up to 1000 mg / kg / day , when a plateau was reached .
The degree of thickening was dose - dependant up to 1000 mg / kg / day , when a plateau was reached .
O O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O