The gender difference was less pronounced at the 60 and 120 mg / kg / day dose groups at study day 28 , probably due to more significant accumulation of the parent compound and the metabolite in males at these dose levels .
The gender difference was less pronounced at the 60 and 120 mg / kg / day dose groups at study day 28 , probably due to more significant accumulation of the parent compound and the metabolite in males at these dose levels .
O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE B-GROUP I-GROUP O O O O O O O O O O O O O O O O O O O O O O O O O