In conclusion , once - weekly dermal administration of COMPOUND_XXX Nail Lacquer containing different concentrations of hydrogen malate ( 100 , 200 or 270 mg base / g formulation ) at 1 mL / kg resulting in dosages of 100 , 200 or 270 mg base / kg or of the Placebo Nail Lacquer to Göttingen minipigs over about 13 weeks was generally well tolerated without clear indication of systemic toxicity .
In conclusion , once - weekly dermal administration of COMPOUND_XXX Nail Lacquer containing different concentrations of hydrogen malate ( 100 , 200 or 270 mg base / g formulation ) at 1 mL / kg resulting in dosages of 100 , 200 or 270 mg base / kg or of the Placebo Nail Lacquer to Göttingen minipigs over about 13 weeks was generally well tolerated without clear indication of systemic toxicity .
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