The toxicokinetic data showed that all dosed rats had measurable plasma levels up to the last bleeding time point ( day 15 , 24 - hour ) , with the exception of 3 rats in the 50 mg / kg / day dose group , which indicated that the majority of the animals were continuously exposed to COMPOUND_XXX during the treatment period .
The toxicokinetic data showed that all dosed rats had measurable plasma levels up to the last bleeding time point ( day 15 , 24 - hour ) , with the exception of 3 rats in the 50 mg / kg / day dose group , which indicated that the majority of the animals were continuously exposed to COMPOUND_XXX during the treatment period .
O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE B-GROUP I-GROUP O O O O O O O O O O O O O O O O O O O