The very few clinical signs at 80 mg / kg , which were observed mainly with minimal incidence and frequency , were considered as not toxicologically relevant and related to exacerbated pharmacological activity of the test substance .
The very few clinical signs at 80 mg / kg , which were observed mainly with minimal incidence and frequency , were considered as not toxicologically relevant and related to exacerbated pharmacological activity of the test substance .
O O O B-FINDING I-FINDING O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O O O O O O O O O O O O O O O O