An additional 36 animals / sex / group received 100 , 200 or 270 mg / kg daily for toxicokinetic evaluations on Days 1 and 28 .
An additional 36 animals / sex / group received 100 , 200 or 270 mg / kg daily for toxicokinetic evaluations on Days 1 and 28 .
O O B-GROUP I-GROUP I-GROUP I-GROUP I-GROUP I-GROUP O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O