Minimal to slight focal , macular or general erythema affecting the whole application area was observed occasionally in one female at 100 mg / kg ( week 4 ) , and the males ( weeks 1 to 4 ) and two females ( weeks 4 to 9 ) at 270 mg / kg .
Minimal to slight focal , macular or general erythema affecting the whole application area was observed occasionally in one female at 100 mg / kg ( week 4 ) , and the males ( weeks 1 to 4 ) and two females ( weeks 4 to 9 ) at 270 mg / kg .
O O O O O O O O B-FINDING O O O O O O O O O O B-SEX O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O B-SEX O O O O O O O O B-SEX O O O O O O O B-DOSE I-DOSE I-DOSE I-DOSE O