The mean systemic exposure ( AUC ( 0 - tiast ) ) of COMPOUND_XXX did not increase over the treatment period of 4 weeks ( steady state ) compared to day 1 ( single dose ) in all dose groups .
The mean systemic exposure ( AUC ( 0 - tiast ) ) of COMPOUND_XXX did not increase over the treatment period of 4 weeks ( steady state ) compared to day 1 ( single dose ) in all dose groups .
O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B-GROUP I-GROUP I-GROUP O