The slight increase in serum calcium at the highest dose of 500 μg / kg COMPOUND_XXX in male animals on days 10 ( p < 0.05 ) , 17 ( n. s. ) and 24 ( n. s. ) and in female animals on days 17 ( n. s. ) and 24 ( n. s. ) is a consequence of the pharmacological action of the compound intervening in the calcium metabolism .
The slight increase in serum calcium at the highest dose of 500 μg / kg COMPOUND_XXX in male animals on days 10 ( p < 0.05 ) , 17 ( n. s. ) and 24 ( n. s. ) and in female animals on days 17 ( n. s. ) and 24 ( n. s. ) is a consequence of the pharmacological action of the compound intervening in the calcium metabolism .
O O B-MANIFESTATION_FINDING O B-STUDY_TESTCD I-STUDY_TESTCD O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE O O B-SEX O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O