e wet - matted fur at several locations ( throat , thorax , fore limbs and nose in males and females ) followed by thinning of fur or hairless areas at these locations were noted also in males and females Â ¢ insertion of gavage was difficult mainly in female animals e disturbances in gait , curved back , drawn in flanks , eyelid closure were noted only in female animals Increased sialorrhea was observed in all animals of all groups ( treatment and control group ) but with higher incidence in the treatment groups ( with dose - dependent increase ) .
e wet - matted fur at several locations ( throat , thorax , fore limbs and nose in males and females ) followed by thinning of fur or hairless areas at these locations were noted also in males and females Â ¢ insertion of gavage was difficult mainly in female animals e disturbances in gait , curved back , drawn in flanks , eyelid closure were noted only in female animals Increased sialorrhea was observed in all animals of all groups ( treatment and control group ) but with higher incidence in the treatment groups ( with dose - dependent increase ) .
O B-FINDING I-FINDING I-FINDING I-FINDING O O O O B-SPECIMEN O B-SPECIMEN O O B-SPECIMEN O B-SPECIMEN O B-SEX I-SEX I-SEX O O O B-FINDING I-FINDING I-FINDING O B-FINDING O O O O O O O O B-SEX I-SEX I-SEX O O O O O O O O O O O O B-FINDING I-FINDING I-FINDING O B-FINDING I-FINDING O B-FINDING I-FINDING I-FINDING O B-FINDING I-FINDING O O O O B-SEX O B-FINDING I-FINDING O O O O O O B-GROUP I-GROUP O B-GROUP I-GROUP I-GROUP I-GROUP O O O O O O O B-GROUP I-GROUP O O O O O O O O