Reducing the dose to about 30 % ( from 1.0 to 0.3 mg / kg ) led to a reduction in the systemic exposure to only about 1.0 - 1.5 % .
Reducing the dose to about 30 % ( from 1.0 to 0.3 mg / kg ) led to a reduction in the systemic exposure to only about 1.0 - 1.5 % .
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