Test article - related organ weight decreases were seen in the thymus at 30 mg / kg in both sexes , thyroid at doses ≥ 3 mg / kg in both sexes , the spleen in females only at doses ≥ 10 mg / kg , and the pituitary in males only at 30 mg / kg .
Test article - related organ weight decreases were seen in the thymus at 30 mg / kg in both sexes , thyroid at doses ≥ 3 mg / kg in both sexes , the spleen in females only at doses ≥ 10 mg / kg , and the pituitary in males only at 30 mg / kg .
O O O O O B-STUDY_TESTCD B-MANIFESTATION_FINDING O O O O B-SPECIMEN O B-DOSE I-DOSE I-DOSE I-DOSE O B-SEX I-SEX O B-SPECIMEN O O O B-DOSE I-DOSE I-DOSE I-DOSE O B-SEX I-SEX O O B-SPECIMEN O B-SEX O O O O B-DOSE I-DOSE I-DOSE I-DOSE O O O B-SPECIMEN O B-SEX O O B-DOSE I-DOSE I-DOSE I-DOSE O