In addition , at the mid dose of 2 mg / kg COMPOUND_XXX and higher : - decreased body weight gain in week 4 as well as over the whole treatment period ; - acinar hypertrophy in the intraorbital lacrimal gland .
In addition , at the mid dose of 2 mg / kg COMPOUND_XXX and higher : - decreased body weight gain in week 4 as well as over the whole treatment period ; - acinar hypertrophy in the intraorbital lacrimal gland .
O O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE O O O O O B-MANIFESTATION_FINDING B-STUDY_TESTCD I-STUDY_TESTCD I-STUDY_TESTCD O O O O O O O O O O O O O B-FINDING I-FINDING O O B-SPECIMEN I-SPECIMEN I-SPECIMEN O