In conclusion , 10 , 50 and 225 mg / kg / day COMPOUND_XXX were no effect dose levels in terms of adverse toxicological findings ( joint , skin and stomach effects ) but that the high dose of 1000 mg / kg / day induced marked lesions , both in - life and histopathologically .
In conclusion , 10 , 50 and 225 mg / kg / day COMPOUND_XXX were no effect dose levels in terms of adverse toxicological findings ( joint , skin and stomach effects ) but that the high dose of 1000 mg / kg / day induced marked lesions , both in - life and histopathologically .
O O O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O O O O O O O O O O O O B-SPECIMEN O B-SPECIMEN O B-SPECIMEN B-FINDING O O O O B-DOSE_QUALIFICATION I-DOSE_QUALIFICATION O B-DOSE I-DOSE I-DOSE I-DOSE I-DOSE I-DOSE O O B-FINDING O O O O O O O O