DISCUSSION AND CONCLUSIONS Single , daily oral administration of the glucokinase activator , COMPOUND_XXX was well tolerated by rats in a four - week toxicity and toxicokinetic study at doses up to 120 mg / kg / day .
DISCUSSION AND CONCLUSIONS Single , daily oral administration of the glucokinase activator , COMPOUND_XXX was well tolerated by rats in a four - week toxicity and toxicokinetic study at doses up to 120 mg / kg / day .
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