diff --git "a/PMC_clustering_407.jsonl" "b/PMC_clustering_407.jsonl" new file mode 100644--- /dev/null +++ "b/PMC_clustering_407.jsonl" @@ -0,0 +1,361 @@ +{"text": "The genomes of two newly emerged Newcastle disease virus strains, chicken/Indonesia/Mega/001WJ/2013 and chicken/Indonesia/Cimanglid/002WJ/2015, from disease outbreaks in chickens in Indonesia are reported. Phylogenetic analysis of different genotypes of Newcastle disease virus using the F gene coding sequences suggests that these two strains belong to genotype VII.2, in class II of avian paramyxoviruses. The genomes of two newly emerged Newcastle disease virus strains, chicken/Indonesia/Mega/001WJ/2013 and chicken/Indonesia/Cimanglid/002WJ/2015, from disease outbreaks in chickens in Indonesia are reported. Phylogenetic analysis of different genotypes of Newcastle disease virus using the F gene coding sequences suggests that these two strains belong to genotype VII.2, in class II of avian paramyxoviruses. Orthoavulavirus (\u2013Newcastle disease (ND) is one of the most severe infectious diseases of chickens. The causative agent, ND virus (NDV), is a member of the avian genus viridae) . NDV is viridae) , 3. NDV viridae) \u20136. Receniridae) \u2013.de novo assembled using Unicycler v0.4.4 with default parameters (HQ697255), respectively. A gap in the sequence of Mega/001WJ was closed using reverse transcriptase PCR (Qiagen) and Sanger sequencing under BioProject number PRJNA613298.The genome sequences for Mega/001WJ and Cimanglid/002WJ were deposited in GenBank with accession numbers"} +{"text": "Scientific Reports 10.1038/s41598-019-55068-z, published online 10 December 2019Correction to: This Article contains a typographical error in the Acknowledgements section.http://ncn.gov.pl), grant DEC 2016/21/B/ST7/02241. The results published here are in part based upon data generated by TCGA managed by the NCI and NHGRI. Information about TCGA can be found at http://cancergenome.nih.gov.\u201d\u201cThis project has received funding from the European Union\u2019s Horizon 2020 Research and Innovation Programme under grant agreement No. 66740, the Academy of Finland, the Sigrid Jus\u00e9lius Foundation, Finnish Cancer Associations and by National Science Centre, Poland (should read:https://ncn.gov.pl), grant DEC 2016/21/B/ST7/02241. The results published here are in part based upon data generated by TCGA managed by the NCI and NHGRI. Information about TCGA can be found at https://cancergenome.nih.gov.\u201d\u201cThis project has received funding from the European Union\u2019s Horizon 2020 Research and Innovation Programme under grant agreement No. 667403 for HERCULES, the Academy of Finland, the Sigrid Jus\u00e9lius Foundation, Finnish Cancer Associations and by National Science Centre, Poland ("} +{"text": "Cell Death & DiseaseCorrection to: 10.1038/cddis.2017.193 published online 18 May 2017Since online publication of this article, the authors noticed that there was an error in Figs."} +{"text": "This article has been corrected: During the assembly of images for Figure 5, the image for Day 1 in the control (PBS) group, seen in panel A, was erroneously copied to Day 2 as well. The corrected Figure 5, obtained using the original data, is shown below. The authors declare that these corrections do not change the results or conclusions of this paper.109894-109914. https://doi.org/10.18632/oncotarget.22493Original article: Oncotarget. 2017; 8:109894\u2013109914."} +{"text": "Drosophila melanogaster (DGRP) allowed us to rediscover three known cases of adaptation at the loci Ace, Cyp6g1, and CHKov1 known to be driven by soft sweeps, and detected additional candidate loci for recent and strong sweeps. Surprisingly, all of the top 50 candidates showed patterns much more consistent with soft rather than hard sweeps. Recently, Harris et al. 2018 criticized this work, suggesting that all the candidate loci detected by our haplotype statistics, including the positive controls, are unlikely to be sweeps at all and that instead these haplotype patterns can be more easily explained by complex neutral demographic models. They also claim that these neutral non-sweeps are likely to be hard instead of soft sweeps. Here, we reanalyze the DGRP data using a range of complex admixture demographic models and reconfirm our original published results suggesting that the majority of recent and strong sweeps in D. melanogaster are first likely to be true sweeps, and second, that they do appear to be soft. Furthermore, we discuss ways to take this work forward given that most demographic models employed in such analyses are necessarily too simple to capture the full demographic complexity, while more realistic models are unlikely to be inferred correctly because they require a large number of free parameters.Whether hard sweeps or soft sweeps dominate adaptation has been a matter of much debate. Recently, we developed haplotype homozygosity statistics that (i) can detect both hard and soft sweeps with similar power and (ii) can classify the detected sweeps as hard or soft. The application of our method to population genomic data from a natural population of Cyp6g1, Ace, and CHKov1. Recently, Harris et al. 2018 have claimed that the selective sweeps we identified are false positives and are more likely to be explained by an admixture demographic history. Moreover, they claim that these neutral non-sweeps are more likely to be hard sweeps rather soft sweeps. Here we re-assess our and Harris et al\u2019s work and find that given a reasonably well-fitting demographic model, soft sweeps are a dominant mode of adaptation in North American Drosophila melanogaster.Whether hard versus soft sweeps dominate adaptation has long been a matter of great debate. Recently, we proposed novel statistics that can identify and differentiate hard and soft sweeps and found that soft sweeps are surprisingly common in North American Drosophila melanogaster. Among our top ranking candidates are three well-known soft sweeps at the loci Drosophila melanogaster. Recent studies suggest that (i) ~50% of amino acid changing and non-coding substitutions in D. melanogaster evolution were adaptive, and (ii) there are abundant signatures of adaptation in the population genomic data detectable as reductions of neutral diversity in the regions of higher functional divergence and as elevation in the frequencies of derived alleles above neutral expectations base pairs, where Ne is the population size and rho is the recombination rate. As an example, sweeps with s = 0.05% are likely to generate sweeps spanning 10kb windows when rho = 5*10^-7. As rho increases, only those selective sweeps with s>0.05% should be observed in 10kb windows.To circumvent the issue of defining a window size, another approach is to use H-scan or nSL to identWindows defined in terms of SNPs versus base pairs. Windows defined in terms of SNPs are all guaranteed to have the same number of SNPs, which then can be used to define the number and frequencies of haplotypes in a window. These SNP-based windows are fully capable of detecting complete hard sweeps . The selection coefficient and partial frequency of the sweeps were drawn from uniform priors ranging from 0 to 1.S1 FigAce, Cyp6g1, and CHKov1.Each point represents the mean Pi/bp value in a 10Kb window. Red vertical lines indicate the positions of the positive controls, (TIF)Click here for additional data file.S2 FigAce, Cyp6g1, and CHKov1.Each point represents the mean S/bp value in a 10Kb window. Red vertical lines indicate the positions of the positive controls, (TIF)Click here for additional data file.S3 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015 [et al. 2015 [2015 . The disal. 2015 , and (F)al. 2015 . Short i(TIF)Click here for additional data file.S4 Fig, Harris et al. [, and Arguello et al [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . The dislo et al , Harris lo et al , and Arglo et al . The modal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . Short i(TIF)Click here for additional data file.S5 FigFig 3J and 3K) (A) A variant of the Duchen et al. 2013 [et al. 2013 [The distribution of Pi/bp computed in short introns of length 10bps or longer in DGRP data is compared with Pi/bp values computed in two demographic models inferred in this paper to fit the DGRP A val. 2013 admixtural. 2013 . Short i(TIF)Click here for additional data file.S6 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015 [et al. 2015 [2015 . These p2015 . The modal. 2015 , and (F)al. 2015 . The roo(TIF)Click here for additional data file.S7 Fig, Harris et al. [, and Arguello et al [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . These plo et al , Harris lo et al , and Arglo et al . The modal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . The roo(TIF)Click here for additional data file.S8 FigFig 3J and 3K) (A) A variant of the Duchen et al. 2013 [et al. 2013 [These plots quantify the fit of the distributions plotted in al. 2013 admixtural. 2013 . (B) A val. 2013 admixtural. 2013 . The roo(TIF)Click here for additional data file.S9 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015, and (F) the implemented admixture + bottleneck model in Garud et al. 2015. Short intron lengths matching those in data were used were used in simulations. Each simulation contains10x the number of short intron fragments as observed in the data. 2015 . The dis(TIF)Click here for additional data file.S10 Fig, Harris et al. [, and Arguello et al [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . The dislo et al , Harris lo et al , and Arglo et al . The modal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . Short i(TIF)Click here for additional data file.S11 FigFig 3J and 3K) (A) A variant of the Duchen et al. 2013 [et al. 2013 [The distribution of S/bp computed in short introns of length 10bps or longer in DGRP data is compared with S/bp values computed in two demographic models inferred in this paper to fit the DGRP A val. 2013 admixtural. 2013 . Short i(TIF)Click here for additional data file.S12 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015 [et al. 2015 [2015 . These p2015 . The modal. 2015 , and (F)al. 2015 . The roo(TIF)Click here for additional data file.S13 Fig, Harris et al. [, and Arguello et al [S10 Fig. The distribution of S/bp computed in short introns of length 10bps or longer in DGRP data is compared with S/bp values computed in a range of simulated neutral demographic models from Duchen et al. [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . These pn et al. , Harris n et al. , and Argn et al. . The modal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . The roo(TIF)Click here for additional data file.S14 FigFig 3J and 3K) (A) A variant of the Duchen et al. 2013 [et al. 2013 [These plots quantify the fit of the distributions plotted in al. 2013 admixtural. 2013 . (B) A val. 2013 admixtural. 2013 . The roo(TIF)Click here for additional data file.S15 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015 [et al. 2015. The number of analysis windows generated for the simulated models equals the number of analysis windows for the DGRP data, after excluding regions of low recombination rates. The red points indicate the H12 values for the top 50 peaks in the DGRP data.2015 . The DGRal. 2015 , and (F)(TIF)Click here for additional data file.S16 Fig, Harris et al. [, and Arguello et al [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . The DGRlo et al , Harris lo et al , and Arglo et al . The modal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . The num(TIF)Click here for additional data file.S17 FigFig 3J and 3K and are (A) A variant of the Duchen et al. 2013 [et al. 2013 [The two models are depicted in al. 2013 admixtural. 2013 . (B) A val. 2013 admixtural. 2013 . The num(TIF)Click here for additional data file.S18 Fig2015 [Ne = 106 model, (B) a constant Ne = 2.7x106 model, (C) a severe short bottleneck model, (D) a shallow long bottleneck model, (E) the implemented admixture model in Garud et al. 2015 [et al. 2015 [2015 . These pal. 2015 , and (F)al. 2015 . The roo(TIF)Click here for additional data file.S19 Fig, Harris et al. [, and Arguello et al [et al. 2013 [et al. 2013 [et al. 2013 [et al. 2018 [et al. 2019 [, Harris s et al. , and Arglo et al . These pal. 2013 , simulatal. 2013 , simulatal. 2013 , simulatal. 2018 , simulatal. 2019 . The roo(TIF)Click here for additional data file.S20 FigFig 3J and 3K (A) A variant of the Duchen et al. 2013 [et al. 2013 [These plots quantify the fit of the distributions plotted in al. 2013 admixtural. 2013 . (B) A val. 2013 admixtural. 2013 . The roo(TIF)Click here for additional data file.S21 Fig(A) Quantile-quantile plot of H12 values within +/-1 SD of the median value in the DGRP data are compared with a random sample from the fitted Gaussian. The Gaussian was simulated with the mean equalling the median value of H12 in the DGRP data, and the standard deviation estimated from points within 1 standard deviation around the median (Methods). (B) Comparison of distribution of H12 values in DGRP data with that of a simulated Gaussian with a mean and standard deviation from (A). The vertical blue line indicates 11 standard deviations away from the mean of the simulated Gaussian distribution. The red points indicate the H12 values for the top 50 peaks in the DGRP data. (C) QQ-plot of H12 from the entire distribution of DGRP values compared with the same simulated Gaussian from (A). The distribution of H12 values in DGRP data has an extreme elevated tail compared to expectations under a Gaussian (D) QQ-plot comparing H12 values from a constant Ne = 2.7*10^6 model with a Gaussian fitted to its bulk (Methods). Neutral simulations lack the elevated tail present in the data.(TIF)Click here for additional data file.S22 FigWe computed Pi, S, and H12 in variants of the admixture model proposed by Duchen et al. 2013 . The adm(TIF)Click here for additional data file.S23 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with constant population sizes in Europe and North America . In S6 t(TIF)Click here for additional data file.S24 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with constant population sizes in Europe and North America . In S6 t(TIF)Click here for additional data file.S25 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with constant population sizes in Europe and North America . In S6 t(TIF)Click here for additional data file.S26 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with constant population sizes in Europe and North America . In S6 t(TIF)Click here for additional data file.S27 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with constant population sizes in Europe and North America . In S6 t(TIF)Click here for additional data file.S28 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S29 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S30 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S31 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S32 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S33 FigsSummary statistics S, Pi, H12, and LD were measured in admixture models with varying growth rates in Europe and North America . In S11\u2013(TIF)Click here for additional data file.S34 FigSummary statistics S, Pi, H12, and LD were measured in admixture models with varying admixture proportions between Europe and North America . Admixtu(TIF)Click here for additional data file.S35 FigSummary statistics S, Pi, H12, and LD were measured in admixture models with varying amounts of migration between Europe and North America . Migrati(TIF)Click here for additional data file.S36 Figth-30th and the (B) 31st\u201450th peaks in the DGRP scan.Same as (TIFF)Click here for additional data file."} +{"text": "Bone Research 10.1038/boneres.2017.44, published online 26 September 2017Correction to: During a reread of our article previously published in Bone Research, we regrettably found that the second lane of originally published Fig."} +{"text": "Experimental & Molecular MedicineCorrection to: 10.1038/emm.2016.168 published online 17 March 2017After online publication of this article, the authors noticed an error in Fig. In the version of this article originally published, Fig."} +{"text": "Cell Discovery (2020) 6:31Correction to: 10.1038/s41421-020-0168-9 Published online 04 May 20201, an error was identified in the Data availability section. The accession number of the dataset was updated. The corrected Data availability appears below:Following publication of the original articlehttps://bigd.big.ac.cn/gsa.The raw sequence data reported in this paper has been deposited in the Genome Sequence Archive in National Genomics Data Center (Nucleic Acids Res 2020), Beijing Institute of Genomics , Chinese Academy of Sciences, under Project Accession No. PRJCA002413 (GSA Accession No. CRA002497) that are publicly accessible at"} +{"text": "Differential globalization of industry\u2010 and non\u2010industry\u2010sponsored clinical trials. PLoS One. 10(12), 1\u201017. ,2https://doi.org/10.1136/bmjopen-2015-008932.Viergever, R.F., Li, K. (2015). Trends in global clinical trial registration: An analysis of numbers of registered clinical trials in different parts of the world from 2004 to 2013. BMJ Open. 5(9). Major reasons for this trend include the collective promotion of global health and the need to rapidly and effectively respond to threats to human health worldwide. The latest epidemic of Ebola Virus Disease (EVD) showed us that the systems put in place for the development of international clinical research were not ready to face the challenge of controlling that deadly disease.3https://doi.org/10.17226/24739.Keusch, G., McAdam, K., Cuff, P., Mancher, M., Busta, E.R. (2017). Integrating Clinical Research into Epidemic Response. Washington, D.C.: National Academies Press. ,4https://doi.org/10.1016/S0140-6736(17)31602-1.Keusch, G.T., McAdam, K.P.W.J. (2017). Clinical trials during epidemics. Lancet. 389(10088), 2455\u20102457. In addition to EVD, many diseases without new drugs and/or vaccines are listed in the reports published by the World Health Organization (WHO),5https://www.who.int/blueprint/en/.World Health Organization. (2018). A research and development Blueprint for action to prevent epidemics. Retrieved January 20, 2018, from the Global Health Security Agenda (GHSA),6https://www.ghsagenda.org/packages.Global Health Security Agenda.\u202f(2014). Action Packages. Retrieved April 26, 2019 from and the World Bank\u2010sponsored International Vaccine Task Force.7https://doi.org/10.1126/science.301.5637.1182b.Academy of Medical Sciences. (2018). Money and Microbes\u202f: Strengthening Clinical Research Capacity to Prevent Epidemics (English). Washington, D.C.: Publisher. The early 218https://crigh.org/://crigh.org/Clinical Research Initiative for Global Health. (2019). Overview. Retrieved July 24, 2019 from was launched in 2017 corresponding to the Organization for Economic Cooperation and Development (OECD) recommendations9OECD Global Science Forum. (2011). OECD Global Science Forum Facilitating International Cooperation in Non\u2010Commercial Clinical Trials Facilitating International Cooperation in Non\u2010Commercial Clinical Trials Organisation for Economic Co\u2010Operation and Development. Global Science Forum. for better global governance of international non\u2010commercial clinical research. CRIGH will encourage international cooperation to rapidly and efficiently respond to global health challenges which are mentioned above.The Clinical Research Initiative for Global Health (CRIGH)10https://doi.org/10.4172/2167-0870.1000219.Forjuoh, S.N. (2015). Challenges Associated with Multi\u2010institutional Multi\u2010site Clinical Trial Collaborations: Lessons from a Diabetes Self\u2010Management Interventions Study in Primary Care. Journal of Clinical Trials. 05(03). International clinical trials are even more complex than single\u2010country studies due to the diversity of legal and ethical frameworks. Researchers and sponsors who conduct an international and multi\u2010site trial face two problems with ethics reviews: the differences between the countries and duplicate reviews within one country.One of the major challenges is the need for multiple ethics reviews by institutional review boards (IRB) or research ethics committees (REC).11https://doi.org/10.1007/s00134-009-1544-yDruml, C., Wolzt, M., Pleiner, J., Singer, E.A. (2009). Research ethics committees in Europe: Trials and tribulations. Intensive Care Medicine. 35(9), 1636\u20101640. ,12https://doi.org/10.1136/medethics-2012-101282.Veerus, P., Lexchin, J., Hemminki, E. (2014). Legislative regulation and ethical governance of medical research in different European Union countries. Journal of Medical Ethics. 40(6), 409\u2010413. and USA13https://doi.org/10.1378/chest.15-0706.Grady, C. (2015). Institutional review boards purpose and challenges. Chest. 148(5), 1148\u20101155. are widely available, however, there is limited information on ethics review systems for countries in other areas. Therefore, the CRIGH Research Bioethics project, co\u2010chaired by Council on Health Research for Development (COHRED), National Cancer Center Japan, and National Institutes of Health, conducted a cross\u2010sectional survey to understand the differences of ethics review systems and how these could present obstacles for promoting international collaborative trials by non\u2010profit, academic organizations, and to formulate recommendations to overcome these obstacles to facilitate ethical international collaborative health research and clinical trials.Information on the current ethics review system in the EU14https://ec.europa.eu/health/sites/health/files/files/eudralex/vol-1/dir_2001_20/dir_2001_20_en.pdfEuropean Commission. (2019). Directive 2001/20/EC. Retrieved April 26, 2019 from the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) \u2013Guideline for Good Clinical Practice (GCP),15https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E6/E6_R1_Guideline.pdf.ICH Harmonised Tripartite Guideline. (1996). Guideline For Good Clinical Practice. Retrieved April 26, 2019 from Standards and operational guidance for ethics review of health\u2010related research with human participants published by WHO,16https://www.ncbi.nlm.nih.gov/books/NBK310666/pdf/Bookshelf_NBK310666.pdf.World Health Organization. (2011). Standards and Operational Guidance for Ethics Review of Health\u2010Related Research with Human Participants.; 2011. Retrieved April 26, 2019 from and 45 CFR part 46.17https://www.govinfo.gov/content/pkg/CFR-2016-title45-vol1/pdf/CFR-2016-title45-vol1-part46.pdf.45 CFR 46. Retrieved April 26, 2019 from In addition, the information from COHRED\u2019s routine assessment of RECs using RHInnO Ethics18http://www.rhinno.net.RHInnO Ethics. Retrieved April 26, 2019 from was used for the development of the questionnaire. The questionnaire contained 17 items regarding national ethics review system.We developed the survey items referring to four international standards: the EU Clinical Trial Directive (Directive 2001/20/EC),We recruited experts of ethics review system in each country by snowball sampling in Latin America, Oceania, and South East Asia. In African countries, COHRED used its network of research ethics committees to recruit national experts. The experts included chairs of IRBs/RECs, committee members, and a clinical researcher. The survey questionnaire was sent via e\u2010mail or Google Forms to the experts in 41 countries. Data collection periods were from November 2017 to June 2018.We had 31 responses (response rate = 75.7%): 17 in Africa, 9 in Asia, 4 in Latin America, and one from Australia.The legal basis of IRB/REC and the composition of committee members were similarly regulated; 81% (n=25/31) had a national requirement to establish IRB/RECs. Regarding the composition of committee members, 90% (n=28/31) required more than five members including at least one non\u2010scientific member in a committee, and 97% (n=30/31) required Conflict Of Interest management of committee members.There was substantial variation in the number of IRB/RECs Figure , in the Figure Our survey showed the differences in characteristics of ethics review systems, some being potential hurdles for conducting international and multi\u2010site trials: multiple ethics approvals for multi\u2010site trials within a country, lack of trained committee members to properly review the study, or different timeframes for the review. We can make four recommendations for accelerating and improving ethics review of international, multi\u2010site trials based on our survey results.19European Commission, op. cit. note 14. The USA has also planned to mandate single IRB review for multi\u2010site trial within the U.S. National Institutes of Health (NIH) system.20https://doi.org/10.1111/cts.12447.Gordon, V., Culp, M., Wolinetz, C. (2017). Final NIH Policy on the Use of a Single Institutional Review Board for Multisite Research. Clinical and Translational Science. 10(3), 130\u2010132. However, only 13 countries mandate a \u201csingle opinion\u201d for a multi\u2010site trial within their national borders. One challenge is that a single IRB cannot review the local context of each institution included as a research site. Another challenge could be \u201cIRB shopping,\u201d because researchers can choose IRBs for the review, and they can submit protocols to multiple IRBs until one is found that will approve the protocol. Despite these challenges, \u201csingle opinion\u201d would be still beneficial for promoting international and multi\u2010site trials. Countries should at least provide an option for researchers to choose a \u201csingle opinion\u201d approach for a multi\u2010site trial within one country.First, countries should strive to adopt \u201csingle opinion\u201d for multi\u2010site clinical trials. A \u201csingle opinion\u201d approach to multi\u2010site trial review within a country will reduce duplicate reviews and delays caused by the need to re\u2010review. Duplicate reviews within a country are a huge hurdle to promote an international and multi\u2010site trial. The EU has already mandated \u201csingle opinion\u201d for multisite clinical trials carried out in more than one member state since 2001 based on its Clinical Trials Directive.Second, national requirements should include training and continuing education in research ethics for IRB/RECs members. The training of IRB/REC members could improve the protocol review, ensuring response in an adequate time and standardizing its quality. However, not all surveyed countries required training for IRB/REC members. A potential reason may be insufficient availability of educational tools and in multiple languages. Even if a country requires training for IRB/REC members, they cannot have effective education without resources. E\u2010learning approaches could be effective in countries with a large number of IRB/RECs and adequate internet infrastructure, and on\u2010site education could be implemented in countries with a small number of committees or low internet access. We need further discussion on the development of universal training tools in several languages and their availability through online platforms. Among its future activities, our group aims to assess the landscape of available tools.In addition to learning core competencies, IRB/REC members need to be up\u2010to\u2010date with changes in local regulation and their impact on ethics review . Moreover, we should consider streamlining the number of committees within a country to effectively and swiftly implement standardized education since countries with hundreds of IRB/REC represent a challenge to successful training.21https://www.who.int/ethics/review-committee/review_process/en/World Health Organization. (2018). Ethics Review Committee: review process. Retrieved December 25, 2018 from the IRB/REC human resources and their experience, and the internal processes within each country, setting a 60\u2010day maximum provides an estimate for investigators, who could than plan and prepare accordingly before the international trial starts. We need to set minimal timeframe of ethics review to harmonize the starting point of international trials.Third, national requirements should include an adequate timeframe for the ethics review process. It is essential to establish a reasonable timeframe for the trial review, because ethics review in a country which has no timeframe requirement would cause a bottleneck for promoting an international multi\u2010site trial. Although the timeframe may depend on the type of review,Ethics22RHInnO Ethics, op. cit. note 18. also can provide solutions for the issues above, especially in the countries with under\u2010resourced IRBs/RECs and research systems. Many countries in Africa have implemented the RHInnO Ethics platform with support from the European and Developing Countries Clinical Trial Partnership (EDCTP), research funders, and international non\u2010profits. By providing real\u2010time access to a virtual REC Administrator qualified to manage complex clinical research at the level required by, for example, the US Department of Health and Human Services, the RHInnO Ethics platform can provide the ability to conduct high level efficient review in time to virtually any REC Administrator23Kasule, M., Wassenaar, D.R., IJsselmuiden, C., Mokgatla, B. (2016). Silent Voices: Current and Future Roles of African Research Ethics Committee Administrators. IRB Ethics and Human Research. 38(1), 13\u201019. in Africa that has access to internet, and speed up clinical research substantially.24https://doi.org/10.4172/2155-6113.1000658.Mokgatla, B., Bahati, P., IJsselmuiden, C.I. (2017). Enhancing the Efficiency and Quality of African Research Ethics Review Processes \u2013 Through an Automated Review Platform. Journal of AIDS Clinical Research. 8(2), 2. Fourth, technological innovations such as web\u2010based ethics review management and expert decision support platforms including RHInnO While we realize that working globally entails working with and respecting national autonomy, especially in the ethics of research, we also want to emphasize that it is time to harmonize ethics review processes for international multi\u2010site trials as an effective and low\u2010cost manner to achieve global health."} +{"text": "Open Biol.10, 190273. (Published Online 26 February 2020) (doi:10.1098/rsob.190273)This correction refers to an error in the affiliation of author \u2018Tsung-Ming Chen\u2019. It should be:3Department and Graduate Institute of Aquaculture, National Kaohsiung University of Science and Technology, Kaohsiung, Taiwan.This has now been corrected."} +{"text": "Correction to: BMC Infect Dis 20, 300 (2020).10.1186/s12879-020-05033-3Incorrect description: The data of the TB cases in Guangxi from January 2012 to June 2019 was obtained from the Guangxi center for Disease Control and Prevention, China (please see Data source section.http://wsjkw.gxzf.gov.cn/zfxxgk_49572/ggws/fdcrbyqgb/t5518731.shtml).Corrected sentence: The data of the TB cases in Guangxi from January 2012 to June 2019 was obtained from the website of Guangxi Health Management Committee .The research did not involve any direct participation by human subjects. The TB data were extracted from monthly reports maintained on public website ("} +{"text": "The sixth author\u2019s name is spelled incorrectly. The correct name is: Nilson Ivo Tonin Zanchin.https://doi.org/10.1371/journal.pntd.0006871The correct citation is: Borja LS, Coelho LB, Jesus MSd, de Queiroz ATL, Celedon PAF, Zanchin NIT, et al. (2018) High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil\u2014A Phase II study. PLoS Negl Trop Dis 12(10): e0006871. The authors apologize for the errors in the published article."} +{"text": "Correction to: Cell Commun Signal (2016) 14:32https://doi.org/10.1186/s12964-016-0157-7Unfortunately, after publication of this article , it was AcknowledgementsWe are grateful for the technical support by Aruna Visavadiya, Ying Li, and Rhesa Dykes. Dr. Britta Engelhardt (Theodor Kocher institute) is thanked for providing the bEnd5 cells.FundingThis work was supported by NIH grant NS45734 and in part by NIH grant C06RR0306551 and the ETSU College of Medicine.Further to this, a duplicate image in Fig."} +{"text": "Toxoplasma gondii is a protozoan parasite that is the causative agent of toxoplasmosis, an infection with high prevalence worldwide. Most of the infected individuals are either asymptomatic or have mild symptoms, but T. gondii can cause severe neurologic damage and even death of the fetus when acquired during pregnancy. It is also a serious condition in immunodeficient patients. The life-cycle of T. gondii is complex, with more than one infective form and several transmission pathways. In two animated videos, we describe the main aspects of this cycle, raising questions about poorly or unknown issues of T. gondii biology. Original plates, based on electron microscope observations, are also available for teachers, students and researchers. The main goal of this review is to provide a source of learning on the fundamental aspects of T. gondii biology to students and teachers contributing for better knowledge and control on this important parasite, and unique cell model. In addition, drawings and videos point to still unclear aspects of T. gondii lytic cycle that may stimulate further studies. Toxoplasma gondii is the causative agent of toxoplasmosis that is a zoonosis of significant medical and veterinary importance and is transmitted by several pathways. Marked advances regarding the control of several infectious diseases caused by parasitic protozoa have taken place in the last decades, especially those that spend part of their life-cycle inside host cells. Nevertheless, the epidemiological control and development of new chemotherapeutic agents with low toxicity and high specificity continue to constitute great challenges. Some of these diseases are restricted to specific areas of the world, as in the case of Chagas disease. Others, like toxoplasmosis, are widely distributed throughout the world .Additional file 6: Figure S6. Tachyzoite. Abbreviations: c, conoid; R, rhoptry; A, acidocalcisome; m, microneme; DG, dense granule.Additional file 7: Figure S7. Four Membranes of apicoplast (arrows). Inset, relative position of the apicoplast (A) to the nucleus (N) and Golgi complex (GC). (Image courtesy Dr. Erica Martins Duarte).Additional file 8: Figure S8. Scheme of sporozoite.Additional file 9: Figure S9. Scheme of bradyzoite.Additional file 10: Figure S10. Bradyzoite. Amylopectin granules (arrow).Additional file 11: Figure S11. Sporocyst suture of curved plates (arrowheads).Additional file 12: Figure S12. 3D scheme of a sporulated oocyst containing two sporocysts with 4 sporozoites each.Additional file 13: Figure S13. Section view of a sporulated oocyst.Additional file 14: Figure S14. Tachyzoite (purple) adhered to a lymphocyte (beige) [17].Additional file 15: Figure S15. Tachyzoite (purple) invading a macrophage (beige).Additional file 16: Figure S16. Parasitophorous vacuole: rosette of tachyzoites (purple), filamentous network (pink). Host cell (beige)Additional file 17: Figure S17. Sequence of intracellular cycle. a Adhesion, secretion of ropthries. b Moving junction: T. gondii assumes an hourglass shape. c Secretion of dense granules inside the parasitophorous vacuole. d Division, formation of the intravacuolar network, accumulation of acidocalcisomes (green) in the residual body. e Rosette of parasites. f Individualization and egress of parasites.Additional file 18: Figure S18. Cystogenesis. a Invasion. b establishment of parasitophorous vacuole. c Division. d Bradyzoite secretion. e, f Cyst wall thickens, bradyzoites continue to divide. g The cyst inside the host cell.Additional file 19: Figure S19. Tissue cyst in the brain of a mouse. Bradyzoites (purple) surrounded by a thick cyst wall (yellow). Blood vessel (red).Additional file 20: Figure S20. Tissue cyst. A cystwall (arrowhead). Amylopectin granules (asterisk), granular matrix (black star).Additional file: Video S1. Part 1- Life cycle of T. gondii in the feline host.Additional file: Video S2. Part 2- Life cycle of T. gondii in the human intermediate host.Additional file 23. Slide show of T. gondii biological cycle, developmental stages and main organelles."} +{"text": "Bioinformatics (2019) doi: 10.1093/bioinformatics/btz828Correction text: The first version of this article placed the index of summation after, rather than below, the sum symbol in Equations 2, 3, and 4. This has now been corrected online. The publisher apologises for the error."} +{"text": "British Journal of Cancer (2014) 111, 1293\u20131304; 10.1038/bjc.2014.410, published online 22 July 2014Correction to: Since the publication of this paper, the authors have been alerted by a reader to a duplication of the NTS non-treated and treated bands appearing in Fig."} +{"text": "In the manuscript \u201cIn time: The value and global implications of newborn screening for severe combined immunodeficiency\u201d, DOI: 10.1590/1984-0462/;2018;36;4;00020, published in the Rev Paul Pediatr. 2018;36(4):388-397:Page 388:Where it reads:Cristina MeehanaJolan WalterIt should read:Cristina A. MeehanJolan E. WalterPage 389:Page 389: Where it reads:It should read:Page 390, first column:Where it reads:It should read:Page 390, second column:Where it reads:11,29,30However, since the implementation of SCID NBS depends on state legislatures, the implementation time is variable across the United States. Since the first pilot program began in Wisconsin in 2009, 47 of the 50 states, the District of Columbia and Puerto Rico have sequentially implemented or have committed to implement SCID NBS .It should read:11,29,30Since the first pilot program began in Wisconsin in 2008, all 50 states, the District of Columbia and Puerto Rico have sequentially implemented SCID NBS Where it reads:It should read:Page 394,Where it reads:[...] Analysis of screening of three million newborns for SCID after the initiation of SCID NBS confirmed a higher-than-expected prevalence of 1:58,000, increasing from 1:100,000 in 2009 prior to NBS. [...]It should read:25 [...][...] Analysis of screening of three million newborns for SCID after the initiation of SCID NBS confirmed a higher-than-expected prevalence of 1:58,000, increasing from 1:100,000 in 2008 prior to NBS.Where it reads:We thank and acknowledge Dr. Jane Carver from the University of South Florida, for their assistance in the editing of this document.It should read:We thank and acknowledge Dr. Jane Carver from theUniversity of South Florida for assistance in editing this document.Page 395,Where it reads:30. Jeffrey Modell Foundation. Newborn screening for SCID. Update on the implementation of newborn screening for SCID in the United States [Internet]. August 2018 . Available at: http://www.info4pi.org/ town-hall/newborn-screeningIt should read:30. Adapted from Jeffrey Modell Foundation. Newborn screening for SCID. Update on the implementation of newborn screening for SCID in the United States [Internet]. December 2018 . Available at: http://www.info4pi.org/ town-hall/newborn-screening."} +{"text": "Cyanoacrylate alone or in combination with other interventions, can be used to achieve variable rates of success in preventing rebleeding. Our study aims to assess the pooled risk of gastric and esophageal varices rebleeding after an initial treatment with cyanoacrylate alone and/or in combination with other treatments, by a systematic review of the literature and pooled analysis.STATA Version 15 which was also used to generate forest plots for pooled analysis. The random or fixed effect model was applied depending on the heterogeneity (I2).PubMed, EMBASE, SCOPUS, and the Cochrane library were searched for studies that reported the risk of rebleeding during the follow-up period after treatment of gastric or esophageal varices with either cyanoacrylate alone or in combination with other treatments. Standard error, upper and lower confidence intervals at 95% confidence interval for the risk were obtained using A total of 39 studies were found to report treatment of either gastric or esophageal varices with either cyanoacrylate alone or in combination with other treatments. When gastric varices are treated with cyanoacrylate alone, the risk of rebleeding during the follow-up period is 0.15. When combined with lipiodol; polidocanol or sclerotherapy the rebleeding risks are 0.13 (CI:0.03\u20130.22), 0.10(CI:0.02\u20130.19), and 0.10(CI:0.05\u20130.18), respectively. When combined with percutaneous transhepatic variceal embolization; percutaneous transhepatic variceal embolization; endoscopic ultrasound guided coils; or with ethanolamine, the rebleeding risk are 0.10(CI:0.03\u20130.17), 0.10(CI:0.03\u20130.17), 0.07(CI:0.03\u20130.11) and 0.08(CI:0.02\u20130.14), respectively.When esophageal varices are treated with cyanoacrylate alone, the risk of rebleeding is 0.29(CI:0.11\u20130.47). When combined with percutaneous transhepatic variceal embolization; sclerotherapy; or band ligation, the risks of rebleeding are 0.16(CI:0.10\u20130.22), 0.12(CI:0.04\u20130.20) and 0.10(CI:0.04\u20130.24), respectively. When combined with a transjugular intrahepatic portosystemic shunt; or ethanolamine, the risks of rebleeding are 0.06(CI: \u2212\u20090.01-0.12) and 0.02 (CI: \u2212\u20090.02-0.05), respectively.In treating both gastric and esophageal varices, cyanoacrylate produces better results in terms of lower risk of rebleeding when combined with other treatments than when used alone. The combination of cyanoacrylate with ethanolamine or with endoscopic ultrasound guided coils produces the lowest risk of rebleeding in esophageal and gastric varices, respectively. We call upon randomized trials to test these hypotheses. Liver cirrhosis is the leading cause of portal hypertension which in turn, leads to portal hypertension and gastrointestinal varices. Up to 17% of liver cirrhosis patients will develop esophageal varices, while 15% will develop gastric varices. Up to 30%, gastroesophageal varices will bleed within 2\u2009years .From older literature, half of the variceal hemorrhages would stop spontaneously however, the risk of rebleeding and mortality increases significantly . CurrentAlso known as \u201ctissue glue\u201d, tissue adhesives were approved by the United States of America\u2019s Food and Drug Authority in 1998, however, there have been previous studies reporting their use as back as the year 1981 , cyanoacCyanoacrylate can be used alone or in combination with other interventions, to achieve variable rates of successes in hemostasis, reducing mortality and prevention of rebleeding. Our study was aimed at assessing the overall risk of gastroesophageal rebleeding after an initial treatment with cyanoacrylate alone and/or in combination with other treatments, by a systematic review of literature and pooled analysis.The current study involved participants with bleeding gastroesophageal varices who underwent hemostasis by cyanoacrylate injection alone or in combination with other treatments. Observational and interventional studies reporting the risk of rebleeding after hemostasis treatment were included. Extending the external validity, eligible English published literature from across the world were included.Four online databases, namely PubMed, EMBASE, SCOPUS, and the Cochrane library were systematically searched with no time range specified. Secondary referencing of eligible studies extended the search scope. The last search was conducted on 4th March 2020.EndNote X9 which kept track of references.Advanced search tools employing MeSH and keywords, were utilized in all three online databases. Using PubMed, advanced search was done as; (cyanoacrylate [MeSH Terms]) AND endoscopic hemostasis [MeSH Terms]) AND esophageal varices [MeSH Terms]) OR gastric varices [MeSH Terms]) AND reble*. The search was repeated as; (adhes*) AND endosc*) AND varic*) AND reble*. The searches were independently performed by two authors; ZH and JS. Results were exported to Two authors screened titles and abstracts of all articles from online database searches to identify the most relevant articles in line with our study question. The relevant articles were sought for full texts and finally included studies were identified after thorough reading full text articles to assess inclusion and exclusion criteria. This process was done by two authors; ZH and JS with the third author, TL assisting to resolve discrepancies. The search, screening, and study identification process are summarized in Fig.\u00a0Before the data extraction process from full-text articles meeting eligibility criteria for inclusion, assessment for methodological biases was done by using the Joanna Briggs institute meta-analysis of statistics assessment and review instrument. PRISMA of the studies when analyzing the outcomes. The fixed effect model was used when I2 was less than 50% and the random effect model was used when I2 was more than 50% indicating significant heterogeneity.The risk of rebleeding was calculated dividing the number of patients rebleeding during the follow-up period after endoscopic hemostasis by the total number of patients that initially underwent the endoscopic hemostasis procedure. The denominator did not include patients lost during the follow up. Standard error, upper and lower confidence intervals for the risk, were obtained from the \u201cgenerate command\u201d in computer software Participants were considered to have been correctly diagnosed with upper gastrointestinal bleeding due to gastric or esophageal varices, and not due to other causes such as Mallory-Weiss tear or gastritis. Despite the country under which treatment was given, all patients were considered to have received standard care.Webb et al. (1981) did. (2003) and Smitet al. 20 [14] uti. (2004) and Zhan. (2007) used KorTable\u00a0A total of 39 studies reported 3630 who had either gastric or esophageal variceal and underwent hemostasis with cyanoacrylate alone or in combination with other treatments. A total of 497 had gastric or esophageal recurrent bleeding episodes during the follow-up period.Figure\u00a02 of 99.7%, p-Value<\u20090.05. This led us to conduct sensitivity analysis, eliminating peculiar studies from the analysis. Figure\u00a0Ramond et al. (1989) [Soga et al. (2010) [D\u2019Imperio et al. (1996) [Omar et al. (1998) [Noophun et al. (2005) [Rivet et al. (2009) [Cheng et al. (2010) [Binmoellar et al. (2011) [Tantau et al. (2013) [Kind et al. (2000) [Tan et al. (2006) [Procaccini et al. (2009) [Choudhuri et al. (2010) [Mishra et al. (2010) [Liao et al. (2013) [Singh et al. (2016) [Cheng et al. (2007) [Kuo et al. (2007) [Huo et al. (2009) [Kang et al. (2011) [Al-Baward et al. (2016) [Xiaoqing et al. (2019) [Evrad et al. (2003) [Hong et al. (2009) [Soga et al. (2010) [Liu et al. (2019) [Sigh et al. (2016), Procaccini et al. (2009), and Kind et al. (2000) were excluded for distinct follow-up times. Each of the 4 remaining studies had an estimate of 2\u2009years of follow-up. The resulting overall pooled risk was 0.15 with no significant heterogeneity .There was a significant heterogeneity observed with I. 1989) and Soga. 2010) were cas89 and S10 were . (2005) , Rivet e. (2009) , Cheng e. (2010) , Binmoel. (2011) and Tant. (2013) had less. (2000) , Tan et . (2006) , Procacc. (2009) , Choudhu. (2010) , Mishra . (2010) , Liao et. (2013) , Singh e. (2007) , Kuo et . (2007) , Huo et . (2009) , Kang et. (2011) , Al-Bawa. (2016) and Xiao. (2003) , Hong et. (2009) , Soga et. (2010) and Liu . (2019) were exc2 of 0.0%, p-Value\u2009=\u20090.53.7).Figure\u00a0Thakeeb et al. (1995) [Maruyama et al. (2010) [Thakeeb reported 3 (i.e. risk\u2009=\u20090.052) rebleeding events among gastric variceal patients; and one (risk\u2009=\u20090.017) rebleeding events among esophageal varices patients. Maruayama reported 10 (i.e. risk =0.5) rebleeding events among gastric varices patients. Figure\u00a0Two studies illustrated treatment with a combination of cyanoacrylate and ethanolamine; . 1995) and Maru. (2010) . Thakeeb and MarBhat et al. (2016) [Robles-Medranda et al. (2019) [Bhat et al. (2016) reported 10 rebleeding events out of 125 gastric varices patients who were followed-up. This corresponds to the risk of 0.08 . Robles-Medranda et al. (2019) reported 1 rebleeding event out of 27 gastric varices patients, which corresponds to the risk of 0.04 . Figure\u00a0Two studies illustrated treatment with a combination of cyanoacrylate and coils guided by endoscopic ultrasound; . 2016) and Robl. (2019) . Bhat et and RobZhang et al. (2007) [Zhang et al. (2008) [Tian et al. (2011) [Three studies illustrated treatment with a combination of cyanoacrylate and percutaneous transhepatic variceal embolization in gastroesophageal varices; . 2007) and Zhan. (2008) involved. (2011) involved and ZhaFeretis et al. (1995) [Dhiman et al.(2002) [Two studies assessed the efficacy of a combination of cyanoacrylate and sclerotherapy in the treatment of gastroesophageal varices. In one study, . (1995) comparedl.(2002) assessedShi et al. (2014) [p-Value of 0.04. In another study, Ma et al. (2018) [In their study, . (2014) compared. (2018) combinedDai et al. (2017) [Zeng et al. (2017) [. (2017) compared. (2017) comparedTable\u00a0Through decades-long progressive improvements in the treatment of gastroesophageal varices, cyanoacrylate has evolved to be one of the favored first lines of treatment. The current study was aimed at utilizing a systematic review of literature and pooled analysis to assess the overall risk of gastroesophageal rebleeding after an initial treatment with cyanoacrylate alone and/or in combination with other treatments.Hou et al. (2009) [Following the treatment of gastric varices with cyanoacrylate alone, 25 studies demonstrated different risks of rebleeding from the minimum of 0.04 to a maximum of 0.99 in another study, with the overall pooled risk of 0.30 . However, after getting rid of peculiar studies that increased heterogeneity, the resulting overall pooled risk was 0.15 . This risk of rebleeding coincides with that previously reported by . (2009) but diffRivet et al. (2009) [Evrad et al. (2003) [Esophageal varices treated with cyanoacrylate alone showed the risk of rebleeding ranging from 0.25 to 0.38 in different studies with the pooled overall risk of 0.29 . Following a fewer number of studies, a meta regression could not be conducted. However, authors believe that the reason for the differences between studies to be due to different methodological approaches between the studies as . (2009) followed. (2003) . The autThakeb et al. (1995) but differs from Maruyama who reported a higher risk of 0.5. The difference is accounted for by fewer sample size by Maruyama. On the other hand, when the combination is used to treat esophageal varices the risk of rebleeding is 0.017. From an otherwise weak basis, we hypothesis that esophageal varices in contrast to gastric varices, respond better to the combination of cyanoacrylate and ethanolamine, in terms of lower risk of rebleeding. We call upon clinical randomized clinical trials to test this hypothesis.When cyanoacrylate is combined with ethanolamine in the treatment of gastric varices the pooled risk of rebleeding after treatment is 0.08 . The result aligns with that reported by Bhat et al. (2016) [Robles-Medranda et al. (2019) [From our findings, when cyanoacrylate is combined with endoscopic ultrasound guided coils to treat gastric varices the pooled risk of rebleeding is 0.07. This finding is more or less similar to that reported by . (2016) but is h. (2019) . The reaZhang et al. (2007) [Tian et al. (2011) [When esophageal varices are treated with a combination of cyanoacrylate and percutaneous transhepatic variceal embolization the pooled risk of rebleeding is 0.16. This is coinciding with findings previously reported by . (2011) when theThe risk of rebleeding in gastric varices treated with cyanoacrylate with sclerotherapy was lower by 0.02 from that of esophageal varices treated with the same combination. The difference could partly be due to more or less the same number of sample sizes among the two studies descriptively analyzed. In combination with other treatments such as transjugular intrahepatic portosystemic shunt and balloon-occluded retrograde transvenous obliteration, it is evident that cyanoacrylate improves the efficacy of the treatment of gastroesophageal varices in terms of lowering rebleeding risk.Our study search was limited to English published literature; involved pooling of studies with different sample sizes, different study designs, and different follow-up durations. As demonstrated by Child-Pugh or the model for end-stage liver disease (MELD) classifications, different studies involved participants with different extents of liver damage/cirrhosis. Despite a few studies involving either emergent or electThese were thought to introduce heterogeneity in the pooled analysis. However, authors appraised eligible studies; performed sensitivity analyses, meta-regression, study exclusion, and used random effect models to deal with high heterogeneity among pooled studies. We also utilized PRISMA tools to minimize reporting biases.We call upon robust randomized studies taking into account biases encountered in our study and adequately matching participants by the extent of liver damage/cirrhosis; treatment urgency whether elective or emergency; lesion location and follow-up duration.In treating both gastric and esophageal varices, cyanoacrylate produces better results in terms of lower risk of rebleeding when combined with other treatments than when used alone. The combination of cyanoacrylate with ethanolamine or with endoscopic ultrasound guided coils produces the lowest risk of rebleeding in esophageal and gastric varices, respectively. We call upon randomized trials to test these hypotheses."} +{"text": "Nature Communications 10.1038/ncomms8769, published online 17 July 2015.Correction to: In this Article, there is an error in Fig."} +{"text": "Regenerative Biomaterials 2020doi: 10.1093/rb/rbaa022, Front. Bioeng. Biotechnol. 2017; 5:1-7.\u201d. This error has now been corrected, and the authors apologize for this oversight.In the originally published version of this article, the caption for Figure 8. did not credit the original source of the image: \u201cGrosso A, Burger MG, Lunger A et al. It takes two to tango: coupling of angiogenesis and osteogenesis for bone regeneration."} +{"text": "Chen should be included in the author byline. Joe W. Chen should be listed as the second author, and his affiliation is 1: UC Berkeley-UCSF Graduate Program in Bioengineering, University of California\u2013Berkeley, Berkeley, California, United States of America. The contributions of this author are as follows: Methodology. The correct citation is: Lu B, Chen JW, Maharbiz MM (2019) Ion concentration polarization (ICP) of proteins at silicon micropillar nanogaps. PLoS ONE 14(11): e0223732. https://osf.io/za9xc.The Data Availability statement is incorrect. The raw data underlying Figs 3 and 6 are not provided in the published paper and its Supporting Information files. The authors have provided the raw data via OSF:"} +{"text": "Correction to: Virol J 9, 163 (2012)http://www.virologyj.com/content/9/1/163Following publication of the original article , the autIn Fig. In Fig. In addition, we also repeated the experiments associated with Fig. We declare that the correction does not change the results or conclusions of this paper."} +{"text": "This article has been corrected: The authors requested to replace Figures 1, 2 and 5. The authors uploaded the wrong images by mistake during the preparation of the article. These corrections do not change any of the conclusions of the publication in any means. The corrected Figures 1, 2 and 5 are provided below. . https://doi.org/10.18632/aging.102552Original article: Aging. 2019; 11:11520\u201311540."} +{"text": "National Black HIV/AIDS Awareness Day (NBHAAD) is observed each year on February 7 to highlight the continuing disproportionate impact of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) on the U.S. black or African American (black) population. During 2018, blacks represented 13% of the U.S. population but accounted for 43% of all newly diagnosed HIV infections , was proposed. The plan calls for intensified efforts to diagnose, treat, prevent, and respond to HIV infections in the United States, with an overall goal of reducing new HIV infections by \u226590% by 2030 (MMWR issue presents data on CDC-funded HIV testing and outcomes among blacks who were tested in jurisdictions that are the initial focus of EHE. In these jurisdictions during 2017, blacks accounted for 43.2% of CDC-funded tests and 49.1% of newly diagnosed HIV infections (https://www.cdc.gov/hiv/group/racialethnic/africanamericans. Information about NBHAAD is available at https://www.cdc.gov/hiv/library/awareness/nbhaad.html. A study reported in this"} +{"text": "Int J Epidemiol 2017; 46:348\u201355. doi: https://doi.org/10.1093/ije/dyw098First published online: 8 June 2016, The originally published version of this article contained an algebraic definition of theregression model for interrupted time series (ITS) that could lead to erroneousinterpretations of the estimated parameters. This model was presented in the equation atpage 351, right column, and the following text. We provide here a more accuratedefinition.The correct equation should have been: The following text below the equation at page 351 (right column) and page 352 (leftcolumn), should read:\u201cwhere The R code in Finally, the dyaa118_Supplementary_DataClick here for additional data file."} +{"text": "The correct names are: Asghari Bano and M.D. Ali Babar. The correct citation is: Khan N, Bano A, Babar MDA (2020) Impacts of plant growth promoters and plant growth regulators on rainfed agriculture. PLoS ONE 15(4): e0231426. The word \u201cBiosciences\u201d is misspelled in the second affiliation. The correct affiliation is: Department of Biosciences, University of Wah, Wah Cantt, Pakistan.The publisher apologizes for the errors."} +{"text": "A third of Medicare beneficiaries are enrolled in Medicare Advantage (MA); however, little is known about MA beneficiaries diagnosed with Alzheimer\u2019s disease and related dementias (AD/ADRD). MA plans have incentives that may influence the type of beneficiaries who enroll/disenroll from plans and the documentation of diagnoses. We calculated the prevalence of diagnosed AD/ADRD in 2014 and 2016 in three MA plans representing ~30% of the MA market. We identified beneficiaries \u226565 years of age enrolled in the MA plans in 2014 and 2016. Among eligible beneficiaries, we identified individuals with AD/ADRD using ICD-9 (2014) and ICD-10 (2016) codes included in the Medicare Chronic Conditions Warehouse algorithms for AD/ADRD. We determined the age and sex of beneficiaries diagnosed with AD/ADRD, and whether they disenrolled from the MA plan for any reason within 364 days from the date they were first identified has having AD/ADRD . In 2014 and 2016 the prevalence of AD/ADRD diagnoses was 5.7% and 6.5%, respectively. In 2016, AD/ADRD beneficiaries were on average 82.4 (SD=7.3) years of age, 61.8% female, and had multiple comorbidities. By 364 days post-index, 32% of beneficiaries with diagnosed AD/ADRD had disenrolled from their plan. The characteristics of 2014 beneficiaries with diagnosed AD/ADRD were similar to their 2016 counterparts. In conclusion, MA beneficiaries with AD/ADRD are predominately female, have multimorbidity, and the age-stratified prevalence of AD/ADRD diagnoses is lower than rates reported in traditional Medicare."} +{"text": "Figure 1 was our self-made drawing modified and adapted from:In the original article, there was a mistake in Figure 1 as published. Netter's Surgical Anatomy and Approaches. Philadelphia, PA: Elsevier Saunders (2014).Delaney CP. Glob Surg. (2018) 4:3. doi: 10.15761/GOS.1000196Radjindrin A, Shanmugam V. Does lateral pelvic lymph node matters in rectal cancer. The mistake made was not to mention in the legend of Figure 1 and references that our self-made drawing was adapted from the sources mentioned previously. The authors apologize for any inconvenience, and under no circumstance was it the authors' intention to neglect to declare use of sources. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.The references to Figure 1 have been updated in the original article.Netter's Surgical Anatomy and Approaches. Philadelphia, PA: Elsevier Saunders (2014).Delaney CP. Glob Surg. (2018) 4:3. doi: 10.15761/GOS.1000196Radjindrin A, Shanmugam V. Does lateral pelvic lymph node matters in rectal cancer."} +{"text": "The following information is missing from the Funding statement: Nicholas D. Juleff was funded by Wellcome Trust intermediate-level research fellowship 091726/Z/10/Z.In the Population structure section of the Materials and Methods, a reference is omitted from the first sentence of the first paragraph.The correct sentence is: SNV variants in the inoculum were called by SiNPle using an approximation of the Bayesian calling algorithm in Snape-pooled [41] suitable for high coverage.The reference is: Ferretti L, Tennakoon C, Silesian A, Freimanis G, Ribeca P. SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data. Genes 2019, 10, 561."} +{"text": "JACMP has issued awards to several manuscripts deemed by the Board of Editors to be worthy of the designation \u201cBest Papers.\u201d These awards are selected by a committee of the Board of Editors and are supported by the American Association of Physicists in Medicine (AAPM). I offer my sincere congratulations to the authors of these outstanding contributions to the body of knowledge that comprises clinical medical physics.For the past several years, the http://www.jacmp.org/index.php/jacmp/article/view/4014/2902Yamak D, Pavlicek W, Boltz T, Panse P, Akay M. Coronary calcium quantification using contrast\u2010enhanced dual\u2010energy computed tomography scans. J Appl Clin Med Phys. 2013;14(3). http://www.jacmp.org/index.php/jacmp/article/view/4262/2885Shang Q, Sheplan Olsen L, Stephans K, Tendulkar R, Xia P. Prostate rotation detected from implanted markers can affect dose coverage and cannot be simply dismissed. J Appl Clin Med Phys. 2013;14(3). http://www.jacmp.org/index.php/jacmp/article/view/4062/2838Zhang A, Wen N, Nurushev T, Burmeister J, Chetty I. Comprehensive evaluation and clinical implementation of commercially available Monte Carlo dose calculation algorithm. J Appl Clin Med Phys. 2013;14(2). It is the intent to have one \u201cBest Paper\u201d award winner, the Editor\u2010in\u2010Chief Award, invited to the podium during the Awards and Honors Ceremony of the Annual Meeting of the AAPM to accept the award. http://www.jacmp.org/index.php/jacmp/article/view/4077/2780Beyer G. Commissioning measurements for photon beam data on three TrueBeam linear accelerators, and comparison with Trilogy and Clinac 2100 linear accelerators. J Appl Clin Med Phys. 2013;14(1). By listing the Best Papers of 2013, I would like to honor the award winners for their contributions to the clinical practice of medical physics, and thank the AAPM for its financial support.Michael D. Mills, PhDEditor\u2010in\u2010Chief"} +{"text": "Phys Ther. (2019) 83:237\u201352.\u201dIn the original article, the reference for Marsh et al. [referenParkinsons Dis. (2019) 2019:2478980. doi: 10.1155/2019/2478980.It should be Marsh R, Cole MH, Dissanayaka NNW, Au TR, Clewett S, O'Sullivan JD, et al. The CuePed trial: how does environmental complexity impact cue effectiveness? A comparison of tonic and phasic visual cueing in simple and complex environments in a Parkinson's disease population with freezing of gait. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."} +{"text": "The erratum adds funding information missing from the Acknowledgments section of the originally published version of the article. J. Med. Imag.7(4), 042804 (2020) doi: 10.1117/1.JMI.7.4.042804] was originally published in Vol.\u00a07, Issue 4 of the Journal of Medical Imaging (JMI) on 22 April 2020 with information missing from the Acknowledgments section. Specifically, the authors mistakenly omitted acknowledgment of financial support from FFG-FWO, Grant No.\u00a0861552. The article was republished with the correct, complete funding information on 21 December 2020.This article ["} +{"text": "The name should be indexed as Mbabazi PS. The correct citation is: Hotez PJ, Harrison W, Fenwick A, Bustinduy AL, Ducker C, Mbabazi PS, et al. (2019) Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women. PLoS Negl Trop Dis 13(4): e0007025. There is an error in the article XML causing the eighth author\u2019s name to be indexed incorrectly. The name should be indexed as Kjetland EF."} +{"text": "Article title: The integration of sexual and reproductive health and rights into universal health coverage: a FIGO perspectiveAuthors: Faysal El KakJournal: Sexual and Reproductive Health MattersBibliometrics: Volume 28, Number 1, article 1829796DOI:https://doi.org/10.1080/26410397.2020.1829796This article was originally published in issue 28.1. The article belongs instead to issue 28.2, a themed issue on \u201cUniversal Health Coverage: Sexual and Reproductive Rights in Focus.\u201dThe article has now been republished in the correct issue, 28.2."} +{"text": "Correction to: Trials (2019) 20:725https://doi.org/10.1186/s13063-019-3770-0Originally published phraseAfter publication of our article the auth2018, with 120 patients randomized. Treatment with TMP finished in October 2019. We disposal the data at present. The current protocol version is 2.0, dated 28 September 2018.Correct phraseRecruitment started in September 2018 and is planned to end in October 2019, with 120 patients randomized. Treatment with TMP will be finished in March 2020. We disposal the data at present. The current protocol version is 2.0, dated 28 September 2018.Recruitment started in September 2018 and is planned to end in October"} +{"text": "Correction to: Experimental & Molecular Medicine10.3858/emm.2011.43.8.051, published online 16 June 2011After online publication of this article, the authors noticed an error in the Fig. The authors apologize for any inconvenience caused."} +{"text": "Keynote at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 22.8.2019Video stream:https://vimeo.com/361729502"} +{"text": "Keynote by Enkelejda Kasneci at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 18.8.2019,Video stream of presentation: https://vimeo.com/356314274"} +{"text": "The correct name is: Salim Benkhedda. The correct citation is: Alhabib KF, Gamra H, Almahmeed W, Hammoudeh A, Benkhedda S, Al Jarallah M, et al. (2020) Acute myocardial infarction and acute heart failure in the Middle East and North Africa: Study design and pilot phase study results from the PEACE MENA registry. PLoS ONE 15(7): e0236292. There is also an error in affiliation 5 for author Salim Benkhedda. The correct affiliation 5 is: Cardiology Oncology Collaborative Research Group, Faculty of Medicine, Benkhedda Benyoucef University, Algeria.A research assistant\u2019s name is also spelled incorrectly in the Acknowledgements section. The correct name is: Dahlia Djermane."} +{"text": "Correction: Journal of Neuroinfammation (2022) 19:38\u00a0https://doi.org/10.1186/s12974-022-02397-yThe part of the Data availability statement and Funding information section are missing in the original publication. The missing information are given below.Funding was provided by University of Rochester University Research Award: Targeting AXL in Alzheimer\u2019s disease, Grant Nos. F30AG061939, NIH R01 AG030149, NIH R56 AG066397\u00a0from the National Institutes of Health, and the National Institute on Drug Abuse Intramural Research Program.https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE171195.All data generated or analyzed during this study are available from the corresponding author on reasonable request. Viral vectors used in this work can be obtained from Addgene.org, plasmids 202,540 and 202,541. RNAseq datasets can be found at"} +{"text": "MGT110 4L ORF observed in the MAD/01/1998, MAU/01/2007 and TAN/01/2011 isolates. Furthermore, MOZ/01/2005 and Georgia 2007/1 only differ by a single synonymous SNP in the EP402R ORF, confirming that the closest link to Georgia 2007/1 is a virus that was circulating in Mozambique in 2005.Since the initial report of African swine fever (ASF) in Kenya in 1921, the disease has predominantly been confined to Africa. However, in 2007, an ASF genotype II virus of unknown provenance was introduced to Georgia. This was followed by its rampant spread to 73 countries, and the disease is now a global threat to pig production, with limited effective treatment and vaccine options. Here, we investigate the origin of Georgia 2007/1 through genome sequencing of three viruses from outbreaks that predated the genotype II introduction to the Caucasus, namely Madagascar (MAD/01/1998), Mozambique (MOZ/01/2005), and Mauritius (MAU/01/2007). In addition, genome sequences were generated for viruses from East African countries historically affected by genotype II and Tanzania (TAN/01/2011)) and newly invaded southern African countries (Zimbabwe (ZIM/2015) and South Africa (RSA/08/2019). Phylogenomic analyses revealed that MOZ/01/2005, MAL/04/2011, ZIM/2015 and RSA/08/2019 share a recent common ancestor with Georgia 2007/1 and that none contain the large (~550 bp) deletion in the Asfivirus within the Asfarviridae family, and it is currently the only known double-stranded deoxyribonucleic acid (dsDNA) arthropod-borne virus (arbovirus) [African swine fever (ASF), caused by African swine fever virus (ASFV), is a haemorrhagic fever of domestic pigs with mortality rates approaching 100% . This unbovirus) ,3. The Abovirus) ,5. The gbovirus) ,6.p72) gene encoding virus protein 72 (VP72) [p72 and central variable region (CVR)/B602L data from Mozambique and other East African countries, and for outbreak strains from Madagascar provided the first indication that the origin of Georgia 2007/1 was from the eastern seaboard of Africa [p72 and CVR, that are used for genotype assignment and intra-genotypic resolution, respectively [p72 region of genotype II viruses from diverse African countries confirmed that these ASFVs are homogeneous and share common ancestry [ASFVs group within 24 genotypes (I\u2013XXIV) based on the partial sequences of the C-terminal region of the B646L p2 gene en2 (VP72) ,9,10,11.2 (VP72) ,13. The f Africa . A subseancestry ,15.K177R gene sequence [The first report of ASFV genotype II in Georgia in 2007 marked the start of a major incursion into Eastern Europe, Russia, and later Asia, Western Europe and the Dominican Republic ,18,19,20sequence ,23. Diffhttps://www.sadc.int/member-states (accessed on 31 July 2023)) affected by genotype II. This was achieved by generating complete ASFV genome sequences for three viruses from Mozambique, Madagascar and Mauritius, which predate the 2007 excursion from Africa to Georgia, and four additional viruses (2011\u20132019) from the two SADC countries historically affected by genotype II and the two newly-affected countries .The aim of this study was to investigate the origin of Georgia 2007/1 and the evolutionary relationships of south-east African outbreak strains by sequencing ASFVs from seven southern African development community (SADC) countries Reference Laboratory for ASF at the Transboundary Animal Diseases Laboratory of the Agricultural Research Council\u2014Onderstepoort Veterinary Research (ARC-OVR) in South Africa. These isolates were selected based on temporal and geographical distribution to ensure the representation of seven of the eight SADC countries in which genotype II outbreaks have been reported/recorded. The viruses span a 21-year period using prescribed reaction conditions.The viruses were cultured in primary bone marrow cells (PBMCs), harvested, and purified using a sucrose gradient purification method, as previously described ,26. Virawww.clcbio.com (accessed on 31 July 2023)). Between 41,566,834 and 131,025,188 reads were obtained for each of the samples. Low quality reads and adaptor sequences were removed prior to mapping against the reference sequence Georgia 2007/1 (FR682468.2) and extracting the consensus sequence. De novo assembly was also performed with the reads, and the resulting consensus sequence was compared to the one generated from the mapping analysis. Deletions, insertions and unique point mutations were verified through PCR-Sanger sequencing, with the major deletion described in The viral DNA was used to construct a sequencing library using the Truseq Nano DNA library preparation kit according to manufacturers\u2019 instructions. The libraries were quality controlled using the Qubit fluorometer and PerkinElmer LabChip instruments. Sequencing was performed using an Illumina HiSeq 2500 instrument using the V4 SBS chemistry, generating 2\u00d7 125-bp paired-end reads for each of the samples. Data generated for all seven viruses were analysed using CLC Genomics workbench v9.5.2 and for newly advocated gene targets .Complete genome sequences from genotype II ASFs representing Africa, Georgia 2007/1 (FR682468.2) and representative genomes of the three geographical clades previously described in Europe, Russia and Asia were obtained from GenBank and used to create an alignment with the newly generated consensus sequences . The alihttps://inqababiotec.co.za/ accessed on 31 July 2023) for Sanger sequencing.An approximately 550 bp deletion was detected in MAD/01/1998, MAU/01/2007 and TAN/01/2011 in relation to Georgia 2007/1. In order to validate the deletion, primers were designed to bind to regions flanking the deletion. Primers ASFV6980-F: 5\u2032-CAT ACA GTG TTC CAT GGG ATA-3\u2032 and ASFV8820-R: 5\u2032-GGA CAA CTT CAT CCA ACG G- 3\u2032 were each used at 0.5 \u00b5M, with 2 \u00b5L DNA template in a 25 \u03bcL reaction containing 12.5 \u03bcL GoTaq green master mix . Amplification was performed using a T100 Thermal cycler at an annealing temperature of 55 \u00b0C. The PCR amplicons were run against the O\u2019GeneRuler DNA Ladder Mix and visualised on a 1% agarose gel stained with ethidium bromide prior to submission to Inqaba Biotech, Pretoria, South Africa . Amplification using primers flanking the deleted region, resulted in shorter amplicons for MAU/01/2007, MAD/01/1998, and TAN/01/2011, compared to the other four viruses, thus confirming the ~550 bp deletion .EP402R (I118I) was identified between MOZ/01/2005 and Georgia 2007/1 and the African isolates. A single synonymous SNP in the open reading frame (ORF) a 2007/1 . This SNa 2007/1 . Additioa 2007/1 , 40 synoa 2007/1 and 6 sia 2007/1 , were oba 2007/1 . In conta 2007/1 . Four sya 2007/1 .The polymorphisms were subsequently evaluated for their potential role as markers to delineate the isolates from Africa. Three of the SNPs (MGF360-13L: G177D), (A859L: A427E) and (O61R: I181I) were discriminated between a group consisting of Georgia 2007/1, MOZ/01/2005 and RSA/08/2019 compared to the remaining sequences from Africa . AdditioAn analysis of the intergenic regions (IGRs) indicated two SNPs and two indels in the sequence of TAN/01/2011, which cluster this isolate with previously determined sequences from Tanzania and Malawi . InteresSince the first introduction of genotype II ASFV to Georgia in 2007, the disease has spread across the Caucasus, Europe, Russia, Asia and the Dominican Republic . The comThe complete genome analyses performed in our study indicate that isolates from Mozambique (2005) and South Africa 2019) are more closely related to the Georgia 2007 virus than the latter is to the viruses currently circulating in Europe and Asia . The ful are moreThe viruses from South Africa (RSA/08/2019), Zimbabwe (ZIM/2015) and Malawi (MAL/04/2011), shared a recent common ancestor with Georgia 2007/1 and Mozambique (MOZ/01/2005); the percentage sequence identity ranged from 99.68% to 99.99% amongst the five ASFVs. In contrast to these closely related ASFVs, the sequences of isolates MAD/01/1998, MAU/01/2007 and TAN/01/2011 shared a recent common ancestor with the previously published viruses from Tanzania and Malawi (Tanzania/Rukwa/17/1 LR813622), MAL/19/Karonga (MW856068), TAN/17/Mbagala (ON409982), TAN/17/Kibaha (ON409979) and TAN/20/Mogorogo (ON409983). The divergence observed amongst the genotype II ASFVs from Africa further indicates that the Madagascar/2007 outbreak might have been related to the previous 1998 outbreak on the island, rather than a new introduction related to MOZ/01/2005 and subsequently Georgia 2007/1 ASFVs. A deletion of ~550 bp was detected in the genotype II genome sequences for Madagascar (MAD/01/1998), Mauritius (MAU/01/2007) and Tanzania (TAN/01/2011), which corresponds to a previously described deletion in the 5\u2032 region of Tanzania/Rukwa/17/1, MAL/19/Karonga, TAN/17/Mbagala, TAN/17/Kibaha and TAN/20/Mogorogo ,22,23., MAL/19/Additionally, a significant difference between MAL/04/2011 (this study) and MAL/19/Karonga was obseA comparison of the newly sequenced ASFVs to Georgia 2007/1, indicated 18 SNPs in the IGRs , and 51 Complete genome sequence analysis remains the gold standard in identifying novel SNPs and determining the evolution and molecular epidemiology of a virus population. Unfortunately, this is time-consuming and expensive, resulting in the study of individual markers to ascertain the spread and epidemiology of ASFVs during outbreaks. Various markers have been described to delineate the genotype II ASFVs circulating in Europe and Asia ,30. ThesEP402R between MOZ/01/2005 and Georgia 2007/1, it is suggested that a possible link exists between the founder ASFV in Georgia 2007/1 and viruses circulating concurrently in Mozambique. The study proved that the Georgia 2007/1 virus shared common similarities with RSA/08/2019 (South Africa), ZIM/2015 (Zimbabwe), MAL/04/2011 and MOZ/01/2005 (Mozambique). With regard to the evolutionary relationship between Georgia 2007/1 and ASFVs from this region, the study found a major divergence in viruses before and after Georgia 2007/1, highlighting the presence of ASFV genotype II clusters in Africa. These results underscore the need for sequencing additional genotype II strains from Africa with particular focus on earlier isolates in order to determine how diverse this genotype is.In conclusion, this study provides novel epidemiological findings on the origin of the virus introduced into Georgia in 2007. Due to a single synonymous SNP in the ORF"} +{"text": "J Clin Invest. 2022;132(18):e161400. https://doi.org/10.1172/JCI161400Original citation: J Clin Invest. 2023;133(11):e172059. https://doi.org/10.1172/JCI172059Citation for this corrigendum: After the publication of this paper, the authors became aware of errors in data analysis due to an issue with the barcoding of samples that caused some samples to be excluded. The authors have repeated all of the analysis and corrected Supplemental Figures 5, 6, and 9. The supplemental file has been updated online.The authors regret the errors."} +{"text": "Given two random variables X and Y, the IB finds the stochastic mapping M of X that encodes the most information about Y, subject to a constraint on the information that M is allowed to retain about X. Despite the popularity of the IB, an accessible implementation of the reference algorithm oriented towards ease of use on empirical data was missing. Embo is optimized for the common case of discrete, low-dimensional data. Embo is fast, provides a standard data-processing pipeline, offers a parallel implementation of key computational steps, and includes reasonable defaults for the method parameters. Embo is broadly applicable to different problem domains, as it can be employed with any dataset consisting in joint observations of two discrete variables. It is available from the Python Package Index (PyPI), Zenodo and GitLab.We present To solve this problem, we seek a third random variable M that solves the following optimization problem:I(\u00b7 : \u00b7) is Shannon\u2019s mutual information . MatpEugenio Piasini, University of Pennsylvania (developer)Alexandre Filipowicz, University of Pennsylvania (developer)Jonathan Levine, University of Pennsylvania (developer)Joshua Gold, University of Pennsylvania (consultant)Archive (1)Name: ZenodoPersistent identifier: 10.5281/zenodo.3625785Licence: GNU General Public License v3.0 or laterPublisher: Eugenio Piasini, Alexandre L. Filipowicz, Jonathan LevineVersion published: 1.1.0Date published: 22/02/2021Archive (2)Name: Python Package Index (PyPI)Persistent identifier:https://pypi.org/project/embo/Licence: GNU General Public License v3.0 or laterPublisher: Eugenio Piasini, Alexandre L. Filipowicz, Jonathan LevineVersion published: 1.1.0Date published: 22/02/2021Code repositoryName: GitlabPersistent identifier:https://gitlab.com/epiasini/emboLicence: GNU General Public License v3.0 or laterDate published: 22/02/2021LanguageEnglish(3)In , Embo haEmbo may be extended in several ways. Possible technical upgrades include improving the software\u2019s performance, for instance by rewriting the Blahut-Arimoto algorithm implementation in C, or by using performance-oriented Python libraries such as Numba or Cython. Features that may be added include the estimation of finite sample bounds for the IB . FinallyThe recommended support channel for Embo is via its GitLab projects, where issues can be reported, and patches and merge requests are welcome. Additionally, the maintainers can be contacted directly at their institutional email addresses."} +{"text": "Article title: Association of the endothelial nitric oxide synthase (eNOS) 4a/b polymorphism with the risk of incident diabetic retinopathy in patients with type 2 diabetes mellitus: a systematic review and updated meta-analysisAuthors: Shi Y., Fan, X., Zhang, K., & Ma, Y.Journal:Annals of MedicineBibliometrics: Volume 55, Number 01, 2226908DOI:http://dx.doi.org/10.1080/07853890.2023.2226908When the above article was first published, some of the overall case/control numbers in Table 3 and Table 4 were incorrect due to mistakes made when summing the case/control numbers from the original studies. This error only affected the case/control summary information presented in Table 3 and Table 4.The correct tables can be found below:"} +{"text": "South African Journal of Communication Disorders, 68(1), a832. https://doi.org/10.4102/sajcd.v68i1.832, there was a mistake in In the published article, Pillay, T., & Pillay, M. (2021). Contextualising clinical reasoning within the clinical swallow evaluation: A scoping review and expert consultation. The original incorrect:The revised and updated:The authors apologise for this error. The correction does not change the significance of study\u2019s findings or overall interpretation of the its results or the scientific conclusions of the article in any way."} +{"text": "This is a peer-review report submitted for the paper \u201cInfluence of Mass Media on Italian Web Users During the COVID-19 Pandemic: Infodemiological Analysis.\u201dThank you for providing me the opportunity of serving as a reviewer for this interesting manuscript . The stu1. The text presents some English errors. I recommend a grammar revision.2. Introduction: Present a broader view on the subject to justify the study objectives. Moreover, avoid introducing methodological issues in this section.3. Introduction: Why do people search for health-related information on the internet? How does the pandemic influence this behavior?4. Introduction: What is the impact of infodemiology studies on public health? Also, what is the importance of infodemiological studies to combat the infodemic?5. Introduction: What is Google Trends and what are its utility/advantages for infodemiological studies? The following studies may be helpful:JMIR Public Health Surveill 2020;6(2):e19702. doi: 10.2196/19702. PMID: 32401211Higgins TS, Wu AW, Sharma D, Illing EA, Rubel K, Ting JY, Snot Force Alliance. Correlations of online search engine trends with coronavirus disease (COVID-19) incidence: infodemiology study. JMIR Public Health Surveill 2020;6(2):e19374. doi: 10.2196/19374. PMID: 32338613Rovetta A, Bhagavathula AS. COVID-19-Related Web Search Behaviors and Infodemic Attitudes in Italy: Infodemiological Study. PLoS One 2017;12(10):e0186059. doi: 10.1371/journal.pone.0186059. PMID: 29049315Lotto M, Aguirre PEA, Rios D, Machado MAAM, Cruvinel AFP, Cruvinel T. Analysis of the interests of Google users on toothache information. JMIR Public Health Surveill 2019;5(2):e13439. doi:10.2196/13439. PMID:31144671Mavragani A, Ochoa G. Google Trends in infodemiology and infoveillance: methodology framework. PLoS One 2014;9(10):e109583. doi: 10.1371/journal.pone.0109583. PMID: 25337815Nuti SV, Wayda B, Ranasinghe I, Wang S, Dreyer RP, Chen SI, Murugiah K. The use of Google Trends in health care research: a systematic review. 6. Introduction: The third aspect proposed for investigation is not adequate. The authors go beyond the main scope by introducing a \u201cfake news\u201d analysis. The authors did not define what \u201cfake news\u201d is, and the analysis made is too superficial for the proposed outcome. I recommend that this step be better planned and analyzed, being described in a future manuscript.Discussion section.7. Introduction: Question R4 has already been widely discussed in the literature and can be removed. If necessary, this aspect can be presented in the 8. Methods: The data collection is confusing and needs to be better described. Why were these platforms chosen? What are the main media in Italy and which ones have been selected? Describe in detail how data were collected on each platform.9. Methods: Does analyzing search results on platforms really show the influence of the media? Why was a qualitative study not proposed?10. Methods: What is the infodemic scale? Present it in detail.11. Methods: Is the normalization of media data on the same scale as Google Trends correct? Since the absolute Google Trends data is blind, it doesn\u2019t seem like a valid comparison to me.12. Methods: What test was done to assess seasonality?13. Results: Avoid discussing the results in advance, as in \u201cEvidence supporting causation.\u201d14. Discussion: Only media influence is discussed about Google Trends data. What other factors might influence the findings? Why do people search for information related to COVID-19 during the pandemic?15. Discussion: Compare the findings with previous literature. Several studies have investigated users\u2019 COVID-19\u2013related interests on Google Trends, including in Italy.16. Discussion: Why are technical terms little used? Where does the Italian population learn about the pandemic? How do eHealth literacy and media literacy influence this process?Practical Implications subsection.17. Discussion: Include a Thank you for reviewing the manuscript based on my comments. In general, the suggestions were satisfactorily answered, and the quality of the paper has improved considerably."} +{"text": "The alaIn vitro and in vivo evaluation [the new therapeutic strategy is tested in vitro/in the laboratory and in vivo to assess its efficacy and safety] Cliunteers) ; (e) Regunteers) ; (f) Cliunteers) ; (g) Monunteers) . It is punteers) , 15. Thiunteers) . By the unteers) , 16. Theunteers) .To date, research on the use of stem cells for ASD is at the clinical trials stage \u201329 and tIn agreement with Price we belieAN: Conceptualization, Supervision, Writing\u2014original draft, Writing\u2014review and editing. AH: Supervision, Writing\u2014original draft, Writing\u2014review and editing. GM: Supervision, Writing\u2014review and editing. GN: Supervision, Writing\u2014review and editing. CL: Supervision, Writing\u2014review and editing."} +{"text": "Biol. Open (2019) 8, bio036244 (doi:10.1242/bio.036244).There was an error published in In The authors apologise to readers for this error, which does not impact the results or conclusions of this paper."} +{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-023-37637-5, published online 25 July 2023Correction to: The Acknowledgements section in the original version of this Article was incomplete. It now reads:The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work through a large group Research Project under grant number (R.G.P.2/163/44). Princess Nourah bint Abdulrahman University Researchers Supporting Project number (PNURSP2023R192), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.The original Article has been corrected."} +{"text": "Among gynecological cancers, cervical cancer is the most common cause of cancer\u2010related death in developing countries. This study analyzes the incidence, mortality, and burden of cervical cancer using the Global Burden of Disease (GBD) 2019 study.The GBD (2019) data on cervical cancer was extracted from the Global Health Data Exchange (GHDx) query tool. Age\u2010standardized rate (ASR) incidence, deaths, lost years of life (YLLs), years of life with disabilities (YLDs), and adjusted years of life with disabilities (DALYs) of cervical cancer in women were extracted. Data were extracted globally for 204 countries and groups based on a socio\u2010demographic index (SDI), World Health Organization (WHO) regions, continents, World Bank regions, and 22 GBD regions.The higher standardized age incidence of cervical cancer is in lower SDI countries, Africa, the African region (According to the WHO), and Sub\u2010Saharan Africa (According to GBD regions). The highest deaths of ASR is in countries with low SDI, low\u2010income group, Africa, the African region , and Sub\u2010Saharan Africa (According to GBD regions). According to SDI classification, the highest DALYs ASR is in low SDI countries, World Bank Low\u2010income countries, African and then American continents, African region, Sub\u2010Saharan Africa, and then Latin America & Caribbean\u2010WB (Based on GBD regions).In 2019, incidence, mortality, and DALYs of cervical cancer mostly affected countries with lower socioeconomic status. Given that cervical cancer is highly preventable, access to screening services and the presence of trained and knowledgeable health care staff can reduce illness, suffering, and death caused by this malignancy. It is recommended to use the national and international potentials to reduce the incidence of this malignancy. Also, early detection and treatment of precancerous lesions have prevented a significant proportion of morbidity and mortality associated with cervical cancer.At present, the development of effective prevention programs requires accurate statistics. Statistics, in addition to showing the current situation, make it necessary to take action to improve the situation, allocate the necessary budget and facilities, make purposeful planning, and finally select the best possible approach.2http://ghdx.healthdata.org/gbd-2019/data-input-sources).In summary, the GBD (2019) data on cervical cancer was extracted from the GHDx query tool. GBD (2019) has systematically and comprehensively estimated 286 causes of death, 369 causes of diseases and injuries, and 87 risk factors for 204 countries and regions. Geographically, the GBD divides the world into 7 main regions and 21 subregions. Detailed information on the data sources used in the present study can be found at GBD 2019 , years lived with disability (YLDs), disability\u2010adjusted life years (DALYs), age\u2010standardized incidence, and mortality rates per 100\u2009000 people in 2019 based on socio\u2010demographic Index (SDI) indicators. These variables also included World Bank income levels, continents, WHO regions, and GBD regions. The Socio\u2010demographic Index (SDI) is a composite indicator of a country's lag\u2010distributed income per capita, average years of schooling, and the fertility rate in females under the age of 25\u2009years.In this study, a description of the mentioned indicators was done separately for each group by crude and age\u2010standardized rates. Age\u2010standardized mortality rates can be used to compare national mortality rates without being affected by differences in age distribution across countries. Without such standardization, it would be difficult to determine if the different mortality rates are due to age or other factors.33.1In 2019, a total of 565\u2009541 new cases of cervical cancer with a confidence level (636435\u2013481\u2009524) were reported in women worldwide, with an incidence of ASR of 13.35 cases per 100\u2009000 people. Statistics show that the lower the SDI index is, the higher age\u2010standardized incidence rates of cervical cancer will be so that the highest standardized age incidence can be found in countries with low SDI and the lowest in countries with high SDI. This rate is equal to 8.91 in high SDI countries and 23.21 in low SDI countries. According to the World Bank classification, the incidence of ASR has the lowest value (9.21) in the high\u2010income countries and the highest value (30.29) in the low\u2010income countries. Among the continents, the highest incidence of ASR is in Africa (24.02) and the lowest is in Europe (10.79). According to the World Health Organization (WHO), the highest standard incidence is in the African region and the lowest is in the Eastern Mediterranean region.Also, in general and based on GBD regions, the highest incidence of ASR is in Sub\u2010Saharan African countries (WB) and then Latin America & Caribbean countries.The highest standardized incidence of cervical cancer has been reported to be in Kiribati (108.8), Palau (66.58), Solomon Islands (57), Guinea (53.61), Lesotho (52.77), Zimbabwe (48.95), Botswana (47.63), Eritrea (44.96), Guinea\u2010Bissau (44.77) and Haiti (44.12).However, the lowest standardized incidence of cervical cancer has been reported to be in Egypt (2.84), Syrian Arab Republic (3.25), Kuwait (3.62), Iran (3.99), Jordan (4.03), Iraq 4.61), Palestine (4.66), Turkey (4.67), Malta (4.94) and Saudi Arabia (4.95) and the highest value in the low\u2010income group (19.59). Among the continents, the highest ASR death is in Africa (15.49) and the lowest in Europe (4.02). According to the World Health Organization, the highest standard incidence is in the African region and the lowest in the European region.In 2019, a total of 280\u2009479 new deaths due to cervical cancer with the conference level (238864_313930) were reported among women in the world, with deaths ASR per 10Also in general and based on GBD regions, the highest death ASR is related to Sub\u2010Saharan Africa.The highest standardized deaths rate from cervical cancer has been reported in Kiribati (69.52), Guinea (36.16), Lesotho (35.96), Zimbabwe (31.39), Somalia (30.99), Eritrea (30.26), Palau (29.79), Solomon Islands (29.44), Central African Republic (29.31), and Guinea\u2010Bissau (29.28).Meanwhile, the lowest standardized death rate from cervical cancer has been reported in Kuwait (1.76), Egypt (1.77), Syrian Arab Republic (1.78), Finland (1.78), Malta (1.78), Iceland (1.9), Luxembourg (1.94), Jordan 2.04), Iran (2.06) and Australia (2.14) , from which 8\u2009712\u2009962 were related to YLLs cases and 242\u2009051 to YLDs cases. Also, the worldwide DALYs ASR was reported at 210.64 and this number for YLLs ASR and YLDs ASR was 204.89 and 5.75 respectively. According to SDI classification, the highest DALYs ASR is in low SDI countries and the lowest is in high SDI countries. The YLLs and YLDs ASR are also the highest in low SDI countries.According to the World Bank classification, the highest value of DALYs ASR is related to World Bank Low\u2010income countries and the lowest value is related to high\u2010income countries. Also in the case of YLLs ASR and YLDs ASR, the highest value is related to low\u2010income countries and the lowest value is related to high\u2010income countries.In different continents, the highest DALYs ASR belongs to the African and then American continents. For the YLLs ASR, the highest value belongs to the African continent and the lowest value belongs to the European continent, but for the YLDs ASR the highest value belongs to the African continent and the lowest value belongs to the Asian continent.According to the World Health Organization regions, the highest DALYs ASR is in the African region, followed by the American region, and the lowest is in the Eastern Mediterranean and European regions. But regarding YLDs ASR, the highest value is in Africa and the lowest is in the Eastern Mediterranean regions.Based on GBD regions, the highest standardized age of DALYs, YLLs ASR, and YLDs ASR are in Sub\u2010Saharan Africa and then Latin America & Caribbean\u2010WB.The highest DALYs ASR has been reported in Kiribati (2143.06), Guinea (1143.8), Lesotho (1087.77), Solomon Islands (1018.69), Somalia (1013.76), Eritrea (973.58), Zimbabwe (957.22), Central African Republic (955.25), Guinea\u2010Bissau (937.63) and Mozambique (915.04).And the lowest DALYs ASR has also been reported in Kuwait (44.34), Egypt (45.13), Syrian Arab Republic (46.56), Finland (47.49), Malta (50.94), Iran (54.11), Iceland (54.93), Jordan (55.25), Luxembourg (55.34) and Switzerland (58.09).The highest YLDs ASR has also been reported in Kiribati (39.28), Palau (29.01), Solomon Islands (23.15), Guinea (18.66), Botswana (18.44), Lesotho (17.93), Zimbabwe (17.11), Saint Vincent and the Grenadines (16.95), Sao Tome and Principe (16.65), and Nauru (16.64).Meanwhile, the lowest YLDs ASR has been observed in Egypt (1.14), Syrian Arab Republic (1.39), Kuwait (1.64), Iran (1.74), Jordan (1.78), Palestine (1.83), Turkey (1.97), Iraq (1.99), Sudan (2.21) and Saudi Arabia (2.23).The highest YLLs ASR has been reported in Kiribati (2103.78), Guinea (1125.13), Lesotho (1069.85), Somalia (999.57), Solomon Islands (995.55), Eritrea (957.88), Central African Republic (941.77), Guinea\u2010Bissau (921.96) and Mozambique (899.74).Meanwhile, the lowest YLLs ASR has been reported in Kuwait 42.7), Egypt (43.99), Finland (44.91), Syrian Arab Republic (45.18), Malta (48.55), Iceland (52.06), Iran (52.38), Jordan (53.47) and Switzerland (55.31) has collected data from various sources, data from some areas is limited, which can affect the results of this study. Second, GBD statistics were based on a set of data sources such as cancer registry data and cytological results, while access to these resources is limited in some low\u2010income countries, and estimating statistics may be erroneous. Third, due to several years delay in presentation of cancer data, up to date data not available.zohreh momenimovahed: Data curation ; investigation ; methodology ; project administration ; supervision ; validation ; writing \u2013 original draft ; writing \u2013 review and editing . Afrooz mazidi moradi: Conceptualization ; data curation ; formal analysis ; methodology ; writing \u2013 original draft ; writing \u2013 review and editing . Parang Maroofi: Data curation ; formal analysis ; methodology ; writing \u2013 original draft ; writing \u2013 review and editing . Leila Allahqoli: Conceptualization ; data curation ; methodology ; project administration ; supervision ; writing \u2013 original draft ; writing \u2013 review and editing . Ibrahim Alkatout: Conceptualization ; funding acquisition ; investigation ; project administration ; resources ; supervision ; validation ; writing \u2013 original draft ; writing \u2013 review and editing . Hamid Salehiniya: Conceptualization ; data curation ; formal analysis ; methodology ; project administration ; validation ; visualization ; writing \u2013 original draft ; writing \u2013 review and editing .The authors declare no conflict of interest.The study was approved by the ethics committee of the Birjand University of Medical Sciences . As we used routinely collected anonymized electronic data, patient consent was not required."} +{"text": "Food Science & Nutrition, https://doi.org/10.1002/fsn3.3158. The above article, published online on December 8, 2022 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief Y. Martin Lo, and Wiley Periodicals LLC. The retraction has been agreed upon due to an error in which the incorrect version of the article was published.Preparation and optimization of soy (Katul cultivar) protein isolate cold\u2010set gels induced by CaCl"} +{"text": "BMC Vet Res\u00a019, 143 (2023)Correction: 10.1186/s12917-023-03700-6.Following publication of the original article , the autThe texts currently read:Publication costs financed by the Minister of Science and Higher Education in the rang\u0119 of the program entitled \u201cRegional lnitiative of Excellence\u201d for the years 2019\u20132023, Project No. 010/RID/2018/19, amount of funding 12.000.000 PLN.The texts should read:Publication costs financed by the Minister of Education and Science under the program entitled \u201cRegional Initiative of Excellence\u201d for the years 2019\u20132023, Project No. 010/RID/2018/19, amount of funding 12.000.000 PLN."} +{"text": "Study to compare the effect of casirivimab and imdevimab, remdesivir, and favipiravir on progression and multi-organ function of hospitalized COVID-19 patients Open Medicine 2023;18(1):20230768, DOI: Journal of Clinical Virology Plus: doi.org/10.1016/j.jcvp.2023.100151.Editorial Office decided to retract this article due to significant overlap with the other papers published by the same authors in"} +{"text": "Atypical parkinsonism and self\u2010mutilation: A new lens on the old concept. Clin Case Rep. 2021; 9:e04432. ( The retraction has been agreed upon due to an error at the publisher, which caused a duplicate of the article to be published. The correct version of the article is Salari, M, Etemadifar, M, Ghanbari, K. Atypical parkinsonism and self\u2010mutilation: A new lens on the old concept. Clin Case Rep. 2021; 11:e04958. (https://doi.org/10.1002/ccr3.4958).The above article, published online on 09 July 2021 in Wiley Online Library ("} +{"text": "Article title: Improving clinical outcomes of Barrett\u2019s esophagus with high dose proton pump inhibitors and cryoablationAuthors: Snady, H.Journal:Annals of MedicineBibliometrics: Volume 55, Number 01, pages 1256\u20131264DOI:https://dx.doi.org/10.1080/07853890.2023.2191002The article was processed and published with references 24 to 35 incorrectly ordered. The references have now been renumbered as per intended making sure that the numerical order of citations in the text is retained as such. The article also has one minor layout correction each in Tables 1, 2 and 4."} +{"text": "The majority of literature on cavitary pulmonary coccidioidomycosis is from four decades ago which was prior to the advent of triazoles and focused on surgical treatment. This observational study is a comprehensive retrospective study of pulmonary cavitary coccidioidomycosis from patients at Valley Fever Institute at Kern Medical over the last 12 years. This observational study aims to explore the spectrum of coccidioidal cavities and the evaluation and management of those cavities.IRB approved, retrospective review of electronic medical records of the Valley Fever Institute database was conducted. Demographics, comorbidities, types, and the number of cavities, complications, and medical and surgical treatment were gathered and compared to the literature. PubMed and Google Scholar were searched for cavitary pulmonary coccidioidomycosisOf the initially 276 identified patients, 137 met the inclusion criteria. This study found 52 (37.2%) patients with hemoptysis. One case (0.7%) required radiologic intervention to occlude the bleeding vessel, and one (0.7%) case of hemorrhage required right upper lobe lobectomy. Nine (6.6%) cases exhibited a ruptured cavity. Eight of those cases had initial chest tube placement, of which three did not require surgical intervention. Seven of 137 (5.1%) cases presented with a pleural effusion not associated with a cavity rupture. Five (3.7%) were due to primary coccidioidomycosis. Three of the coccidioidal effusions required therapeutic thoracentesis, and none required a chest tube or surgery. The mean duration of the initial antifungal treatment was found to be 563 days (n=80). In 35% (28/ 80) of them, a triazole was switched to another triazole for variable reasons, including treatment failure or side effects.Coccidioidal pulmonary cavitation remains a complex disease to evaluate and treat. This study's ethnic demographic differed from other cohorts. It also contradicts the notion that pulmonary coccidioidal cavitary disease and dissemination infrequently manifest in the same patient. In the present age of triazole therapy, indications and the need for surgery continue to decline. Further investigation needs to be conducted to evaluate medical therapy\u2019s efficacy and long-term outcomes.Rupam Sharma, PGY-1/MD, Astellas: Grant/Research Support George R. Thompson, III, MD, Astellas: Advisor/Consultant|Astellas: Grant/Research Support|Cidara: Advisor/Consultant|Cidara: Grant/Research Support|F2G: Advisor/Consultant|F2G: Grant/Research Support|Mayne: Advisor/Consultant|Mayne: Grant/Research Support|Melinta: Advisor/Consultant|Melinta: Grant/Research Support|Mundipharma: Advisor/Consultant|Mundipharma: Grant/Research Support|Pfizer: Advisor/Consultant|Pfizer: Grant/Research Support"} +{"text": "This erratum corrects the following:et\u00a0al. A consensus statement from the Japan Diabetes Society: A proposed algorithm for pharmacotherapy in people with type 2 diabetes. J Diabetes Investig. 2023; 14: 151\u2013164. https://doi.org/10.1111/jdi.13960Ryotaro Bouchi, Tatsuya Kondo, Yasuharu Ohta The below statement should have been included in the original version of this article:https://doi.org/10.11213/tonyobyo.65.419) released in Japanese on Volume 65 Issue 8, 2022, on the official website of the Japan Diabetes Society, and has been jointly published in Diabetology International and Journal of Diabetes Investigation .This article is the English version of the \u201cA consensus statement from the Japan Diabetes Society: A proposed algorithm for pharmacotherapy in people with type 2 diabetes\u201d (The online article has been corrected.The publisher apologizes for the error."} +{"text": "Article title: Phosphatidylinositide 3-kinase inhibition: A new potential target for the treatment of polycystic ovarian syndromeAuthors: Shah, K. N. & Patel, S. S.Journal: Pharmaceutical BiologyBibliometrics: Volume 54, Number 6, pages 975\u2013983DOI: https://doi.org/10.3109/13880209.2015.1091482In the version of this article initially published, there was a mistake in the images of normal control groups of Figures 2 and 3.Figures 2 and 3 are now corrected and the article has been republished online."} +{"text": "There was an error in the original publication . In the A correction has been made to the Results Section, Paragraph 1:In 2021, COVID-19 incidence in northwest Russia varied in waves, ranging from 258.8 (per 100 K/month) in April to 1185.8 in November. At the same time, increases in incidence with the achievement of local maxima were recorded in January (1113.5 per 100 K/month), June (822.3 per 100 K/month), and November (1185.8 per 100 K/month) .The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."} +{"text": "Assessment of stress and anxiety in mice with colorectal cancer submitted to physical exercise, which DOI is: https://doi.org/10.1590/acb370508, published in the journal Acta Cir\u00fargica Brasileira, 2022;37(05)e370508, page 5, in the axis X of Figure 5:In the manuscript Instead of:Open ArmOpen ArmOpen ArmShould be:Open ArmClosed ArmCenter"} +{"text": "Page 7, Fig. 4: We found errors in the significance indicator lines of this figure. In particular, there is no significant difference of the percentage of BLV-infected cells between the *016:01/*009:02 group and *009:02/other allele group. Instead, there is a significant difference between the *016:01/*009:02 group and the other alleles group. We note that this does not affect the overall discussion and conclusions. The corrected Volume 8, No. 1, e00493-22, 2023,"} +{"text": "Correction: Journal of Neuroinflammation 2012, 9:251 http://www.jneuroinflammation.com/content/9/1/251Following publication of the original article , the co-Hence, her name has been updated in this correction article."} +{"text": "BMC Infectious Diseases (2023) 23:25310.1186/s12879-023-08197-wThe original publication of this article contained an incorrect funding number, the incorrect and correct information are available in this correction article. The original article has been updated.IncorrectThis work is a part of the research project financed by the National Science Center of Poland, grant number 2019/34/E/NZ6/00221.CorrectThis work is a part of the research project financed by the National Science Center of Poland, grant number 2019/35/B/NZ7/00942."} +{"text": "There are errors in the Funding section. The correct Funding statement is: The authors would like to acknowledge the Fundamental Research Grant Scheme (FRGS) from the Ministry of Higher Education, Grant no: FRGS/1/2018/TK04/UM/02/1 (FP091-2018A)."} +{"text": "In June 2021, IDSA updated its guideline to have fidaxomicin (FDX) as the preferred treatment over vancomycin (VAN) for patients with initial and recurrent CDI. The objective of this study was to examine changes in treatment pattern for CDI and variation in implementation of the guideline recommendation across hospitals.This was a retrospective, observational study using data from the PINC AI Healthcare Database, an electronic laboratory, pharmacy and billing data repository from about 25% of US hospitals. This study included patients aged 18 and older who received CDI treatment during the study period from 1/2020 to 6/2021 (pre-period) and from 10/2021 to 6/2022 (post-period). We first examined the treatment pattern in the pre- and post-periods by calculating the proportion of patients who received FDX on day one of treatment, only FDX, only VAN, only metronidazole (MTZ), switched from VAN or MTZ to FDX, and other treatment patterns. Then we examined proportion of patients receiving FDX on day one at the hospital level. We used a multilevel logistic regression model with hospital random effects to examine the association between hospital characteristics and FDX use. Patient and hospital characteristics were controlled.67,311 CDI patients from 798 hospitals met the inclusion criteria. Figure 1 shows the analysis of CDI treatment pattern at the patient level. The proportion of patients treated with FDX on day one increased from 2.4% in the pre-period to 6.9% in the post-period. Patients who received only FDX increased from 1.3% to 4.1%, and those with a switch from VAN/MTZ to FDX from 3.2% to 6.4%. At the hospital level, the mean use of FDX on day one increased from 2.6% (SD = 4.8%) to 7.9% (SD = 10.1%), and the median increased from 1.1% to 4.2% . We found that FDX use increased proportionately by all hospital characteristics except census region where greater increases were found in the South and Midwest. Hospitals had a statistically significant association with FDX use (p< 0.001) and 29.7% of the variance of FDX use on day one was explained by between-hospital variability.Adjusted Proportion of Treatment Starting with FidaxomicinUse of FDX for CDI treatment has increased since the publication of IDSA guideline in 2021, but it remains low with significant regional variation.Erik R. Dubberke, MD, MSPH, Abbott: Advisor/Consultant|AstraZeneca: Advisor/Consultant|Ferring Pharmaceuticals: Advisor/Consultant|Ferring Pharmaceuticals: Grant/Research Support|Merck and Co.: Advisor/Consultant|Pfizer: Advisor/Consultant|Pfizer: Grant/Research Support|Seres Therapeutics: Advisor/Consultant|Summit: Advisor/Consultant|Theriva Biologics: Grant/Research Support Qinghua Li, PhD, Merck & Co Inc: Employee Engels N. Obi, PhD, Merck & Co Inc: Employee Vladimir Turzhitsky, PhD, Merck & Co.: Full time employee of Merck & Co.|Merck & Co.: Stocks/Bonds Fakhar Siddiqui, MD, MBA, Merck & Co Inc.: Employee Brian H. Nathanson, Ph.D., Merck & Co., Inc: Advisor/Consultant"} +{"text": "The second author's name was spelled incorrectly. The correct name is: Jaap A. Wagenaar.The correct citation is: Bosman AB, Wagenaar JA, Stegeman A, Vernooij H, Mevius D (2012) Quantifying Antimicrobial Resistance at Veal Calf Farms. PLoS ONE 7(9): e44831. doi:10.1371/journal.pone.0044831There is also an error in the Materials and Methods section. In Statistical Analysis, the first sentence of the third paragraph of \"Logistic regression analysis\" should read: The estimated variance values of the random effects in the best fitting model were used to examine the variation in antimicrobial resistance on farm-level, pen-level and sample-level, with the variance of a standard logistic density fixed at \u03c02/3 [26]."} +{"text": "AbstractArachnida: Opiliones). Harvestmen accessible datasets in Iberian Peninsula are unknown, an only two other datasets available in GBIF are composed exclusively of harvestmen records. Moreover, only a few harvestmen data from Iberian Peninsula are available in GBIF network . This paper describes the data associated with the Opiliones kept in the BOS Arthropod Collection of the University of Oviedo, Spain (hosted in the Department of Biolog\u00eda de Organismos y Sistemas), filling some of those gaps. The specimens were mainly collected from the northern third of the Iberian Peninsula. The earliest specimen deposited in the collection, dating back to the early 20th century, belongs to the P. Franganillo Collection. The dataset documents the collection of 16,455 specimens, preserved in 3,772 vials. Approximately 38% of the specimens belong to the family Sclerosomatidae, and 26% to Phalangidae; six other families with fewer specimens are also included. Data quality control was incorporated at several steps of digitisation process to facilitate reuse and improve accuracy. The complete dataset is also provided in Darwin Core Archive format, allowing public retrieval, use and combination with other biological, biodiversity of geographical variables datasets.There are significant gaps in accessible knowledge about the distribution and phenology of Iberian harvestmen (PageBreak Purpose: Existing knowledge on the distribution of harvestmen in the Iberian Peninsula is still very fragmented of Ireland dataset of the National Biodiversity Data Centre (http://data.gbif.org/datasets/resource/10810), with 2,109 records (agmented . There aagmented . However groups) .Opiliones specimens deposited in the BOS Arthropod Collection (subcollection of Opiliones: BOS-Opi) of the University of Oviedo, Spain, comprising 16,455 specimens in 3,772 vials . As a result of this, the BOS-Opi dataset makes a significant contribution of primary data about Iberian harvestmen for ecological, faunistic and conservation studies. With the publication of this dataset, we aim to (1) providing a dataset with phenological and distribution data on harvestmen from the northern third of the Iberian Peninsula, and (2) describing the Opiliones subcollection of the BOS Arthropod Collection.The purpose of this paper is to document a dataset corresponding to Additional information: A list of publications citing harvestmen contained in this dataset (BOS-Opi) is provided in point 2 of the reference section.Project title: Informatizaci\u00f3n de la Colecci\u00f3n de Artr\u00f3podos BOS de la Universidad de Oviedo / Digitisation of the BOS Arthropod Collection of University of OviedoPersonnel digitisation: Torralba-Burrial APageBreakAdministrative contact: Anad\u00f3n ABOS-Opi determination specialist: Merino S\u00e1inz IBOS-Opi collectors: Collectors who have deposited more than 50 specimens include Merino S\u00e1inz I, Anad\u00f3n A, Fern\u00e1ndez-\u00c1lvarez F.A., Torralba-Burrial A, Ocharan Larrondo FJ, Melero Cimas VX, Monteser\u00edn Real S, Ocharan Ibarra R, Rosa Garc\u00eda R, and V\u00e1zquez Felechosa MTP. Franganillo Collection:Curator of Lastra CFunding: Digitisation of this biological collection was supported by the Spanish National R+D+i Plan and PCTI Asturias through a contract for ATB.PageBreakBiodiversity of Muniellos Biosphere Reserve\u201d was supported by the Asturias Regional Government .Almost 73% of the specimens were collected as part of the PhD Thesis by Study area description: Harvestmen specimens deposited in BOS Arthropod Collection are from the northern third of the Iberian Peninsula (eninsula . Most ofeninsula . The clieninsula . Oak andeninsula . Harvesteninsula .Design description: The digitisation process of this dataset (BOS-Opi) was carried out according to the workflow put in place for the Odonata subcollection (BOS-Odo) (http://www.gbif.es:8080/ipt). DarwinCore elements included in the dataset structure are listed in the dataset description section. Data quality controls of geographic, taxonomic and additional data associated with the harvestmen specimens were performed at several steps of digitisation process as an essential part of this Information Management Chain (BOS-Odo) . Prior tnt Chain , 2005b, PageBreakArthropod Collection, allowing free access of citizens, researches, environmental companies and government managements to biodiversity data kept in this Collection.Currently, dataset is being used to study phenological and life history differences of harvestmen species between areas in north Iberian Peninsula with different geographical/habitat features, species distribution and importance of opportunistic data in fill knowledge gaps when standardised sampling data are not available or are incomplete. Moreover, this dataset is considered as a dynamic catalogue of the harvestmen of BOS General taxonomic coverage description: All specimens were identified to species when preservation status, sex and life cycle phase permitted it. Sixty-two species were recorded from the northern third of the Iberian Peninsula and Phalangodidae (suborder Laniatores) are missing. As depicted in Sclerosomatidae , followed by Phalangiidae , Trogulidae , Nemastomatidae (14.0%: Nemastomella and Nemastoma). Other families represent less of 5% of the records descriptions and without figures. In four publications nomina dubia both in Araneae , current identifications more accurate and other specimens show a correct identification by Franganillo .No types are hosted among the ae e.g., and in Oes e.g., , are synes e.g., , or his es e.g., . In 1972es e.g., . The prees e.g., . A studyes e.g., . In Opilna dubia , and mosna dubia . IdentifAnimaliaKingdom: ArthropodaPhylum: ArachnidaClass: OpilionesOrder: Ischyropsalididae, Nemastomatidae, Phalangiidae, Sabaconidae, Sclerosomatidae, Sironidae, Travuniidae, Trogulidae.Family: Common names: Animals, Arthropods, Arachnids, Harvestmen.All specimens are from the northern part of the Iberian Peninsula . Most ofPageBreak40\u00b018'N and 43\u00b042'N Latitude; 8\u00b054'W and 0\u00b030'W Longitude.1900\u201320121977-presentParent collection identifier: Colecci\u00f3n de Artr\u00f3podos BOSCollection name: Colecci\u00f3n de Artr\u00f3podos BOS de la Universidad de Oviedo: Opiliones (BOS-Opi)Collection identifier:http://data.gbif.org/datasets/resource/15038Specimen preservation method: Ethanol 70\u00b0Curatorial unit: 3772 with an uncertainty of 0 )Curatorial unit: 16455 with an uncertainty of 0 (Specimens)Method description: The digitisation process of the Opiliones subcollection (BOS-Opi) was realised in accordance with the published workflow of the Odonata subcollection (BOS-Odo) (see Odo) see .Pre-digitisation phase: The preservation status of harvestmen specimens was reviewed prior to digitisation. Vials were changed when necessary and refilled with preservation liquid (ethanol 70\u00b0). Specimens were identified or identifications were reviewed when they were already noted. Identification labels were added when labels were lacking or otherwise incomplete. Specimens\u2019 vials were sorted alphabetically by family/genus/species names in trays, and hosted in metallic cabinets in a cold chamber.Digitisation phase: A database with DarwinCore v1.2 standard fields and other fields specific to different research projects was developed using MS EXCEL software. All biodiversity data available on the specimens\u2019 labels were included in the database.PageBreakhttp://www.ign.es/iberpix2/visor). Localities were sorted geographically for batch retrospective georeferencing, starting with larger batches from specimen labels or from associated publications were added to the database when available. If coordinates were not present on the specimen labels or in primary publications, retrospective georeferencing see was carr batches . CoordinThe database was converted and imported to, and managed with, ZOORBAR v2.1.1 software .Creation of the dataset: The dataset was exported as a file in DarwinCore v1.2 format and geographic coordinates were carried out with ZOORBAR v2.1.1 software. DarwinCore elements included in dataset structure are listed in the dataset description section. Data format, georeferenced coordinates and absence of ASCII anomalous characters were checked with DARWIN_TEST v.3.2 software (http://www.gbif.es/darwin_test/Darwin_test.php). Erroneous data were corrected and data cleaning was repeated to enhance the data quality .http://www.gbif.es:8080/ipt). Links to these data were also provided on the BOS Arthropod Collection website (http://www.unioviedo.es/BOS/Zoologia/artropodos). The offline version of the dataset includes the identification history of each specimen (4149 items), collection method, research project, and notes on materials derived from the specimens . This information is available on request.The dataset was transformed to a DarwinCore Archive format with metadata to ensure rapid discovery of this biodiversity resource and future publishing as a citable academic paper see . The datStudy extent description: Specimens are mainly from the northern third of the Iberian Peninsula (see geographic coverage section). The earliest specimens are from the 20th century (belonging to the P. Franganillo collection), but the general collection starts in 1977. However, only 9.73% of the items were collected prior to the year 2000, while 75.93% were collected between 2009 and 2012. The BOS-Opi dataset includes the record distributions by month specimens from the PhD dissertation by PageBreak2) specimens from the project \u201cCataloguing of the Biodiversity from the Biosphere Reserve of Muniellos\u201d (SW of Asturias province) (13.10%)3) specimens from other sources: collections from students in Biology and Forestry Engineering programs at the University of Oviedo, other research projects, practical courses, etc. (13.92%).PageBreakmuch lower number of specimens (1.2%) . Ethylene glycol was used as a fixation and preservation liquid in the pitfalls : OpilionesCharacter encoding: UTF-8Format name: Darwin Core Archive formatFormat version: 1.0Distribution:http://www.gbif.es:8080/ipt/archive.do?r=bos-opiPublication date of data: 2013-07-04Update police: Annually when necessary to transmit data of new specimens kept at BOS Collection.Language: SpanishLicenses of use: This dataset [BOS Arthropod Collection of University of Oviedo (Spain): Opiliones (BOS-Opi)] is made available under the Open Data Commons Attribution License: http://www.opendatacommons.org/licenses/by/1.0/.DarwinCore elements: The DarwinCore elements (http://purl.org/dc/terms/) included in the dataset published through the GBIF network describe the specimens\u2019 data to several levels. These elements are: Record data: type (basisofrecord), DateLastModified, InstitutionCode, CollectionCode, CatalogNumber, Collector, IndividualCount, Sex, YearCollected, MonthCollected, DayCollected, Notes (with info about habitat in most of cases); Geographic data: Country, StateProvince, Locality , MinimumElevation (meters), MaximunElevatium (meters), Latitude , Longitude , CoordinatePrecision (meters); Taxonomic data: Kingdom , Phylum , Class , Order , Family, Genus, Species (specificEpithet), ScientificNameAuthor (auPageBreakthorship of taxa name), ScientificName, Identified by, Yearidentified, Type status. Moreover, some DarwinCore elements were mapped to fixed values in the IPT as described in this data-paper: language, rights, rightsHolder, bibliographicCitation, references, datasetID, datasetName, ownerInstitutionCode.Object name: BOS Arthropod Collection of University of Oviedo (Spain): OpilionesCharacter encoding: iso-8859-1Format name: Darwin Core ArchiveFormat version: 1.0Distribution:http://data.gbif.org/datasets/resource/15038Metadata language: EnglishDate of metadata creation: 2013-06-12Hierarchy level: Dataset"} +{"text": "The name of the gene (BCMO1) was spelled incorrectly in the title.The title should be: Detection of a Cis eQTL Controlling BCMO1 GeneExpression Leads to the Identification of a QTG for Chicken Breast Meat ColorThe corrected citation is: Le Bihan-Duval E, Nadaf J, Berri C, Pitel F, Graulet B, et al. (2011) Detection of a Cis eQTL Controlling BCMO1 Gene Expression Leads to the Identification of a QTG for Chicken Breast Meat Color. PLoS ONE 6(7): e14825. doi:10.1371/journal.pone.0014825"} +{"text": "The name of the first author of the article is incorrect. The first author's correct name is: Chong Leong Gan. The correct Citation is: Chong Leong G, Uda H (2013) Comparative Reliability Studies and Analysis of Au, Pd-Coated Cu and Pd-Doped Cu Wire in Microelectronics Packaging. PLoS ONE 8(11): e78705. doi:10.1371/journal.pone.0078705. The correct abbreviation of the first author's name in the Author Contributions statement is: CLG."} +{"text": "Shigella Pathogenicity Puzzle: Spermidine Accumulation by Silencing of the speG Gene. The correct citation is: Barbagallo M, Di Martino ML, Marcocci L, Pietrangeli P, De Carolis E, et al. (2011) A New Piece of the Shigella Pathogenicity Puzzle: Spermidine Accumulation by Silencing of the speG Gene. PLoS ONE 6(11): e27226. There was a typographical error in the title. The correct title is: A New Piece of the"} +{"text": "The name of the first author is incorrectly represented in the Citation and Copyright. The correct Citation is: Abu Awad D, Gallina S, Bonamy C, Billiard S (2014) The Interaction between Selection, Demography and Selfing and How It Affects Population Viability. PLoS ONE 9(1):e86125. doi:10.1371/journal.pone.0086125.The Copyright statement should read: \"\u00a9 2014 Abu Awad et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.\""} +{"text": "Correction to:British Journal of Cancer (2011) 104, 1410\u20131417; doi:10.1038/bjc.2011.94When published originally, earlier in Volume 104, the authors noticed that they had omitted to include TRDRP grant (19XT-0051) in the acknowledgements, which funded a large portion of the work for this paper. The authors are now happy to correct this omission."} +{"text": "Acta Cryst. (2010), E66, o2633.Corrigendum to Acta Cryst. (2010), E66, o2633] is corrected.The author list in the paper by Ding [ In the paper by Ding (2010)"} +{"text": "The name of the third author was given incorrectly. The correct name is: Markus von Nickisch-Rosenegk. The correct citation is: Hoppe S, Bier FF, von Nickisch-Rosenegk M (2013) Rapid Identification of Novel Immunodominant Proteins and Characterization of a Specific Linear Epitope of Campylobacter jejuni. PLoS ONE 8(5): e65837. doi:10.1371/journal.pone.0065837. The abbreviation in Contributions correctly reflects the name as it is."} +{"text": "The word \"Systematic\" is misspelled in the title.The correct title is: The Scale of Faith Based Organization Participation in Health Service Delivery in Developing Countries: Systematic Review and Meta-Analysis.The correct citation is: Kagawa RC, Anglemyer A, Montagu D (2012) The Scale of Faith Based Organization Participation in Health Service Delivery in Developing Countries: Systematic Review and Meta-Analysis. PLoS ONE 7(11): e48457. doi:10.1371/journal.pone.0048457"} +{"text": "Porcine reproductive and respitatory syndrome virus (PRRSV) is a recently emerged pathogen and severely affects swine populations worldwide. The replication of PRRSV is tightly controlled by viral gene expression and the codon usage of translation initiation region within each gene could potentially regulate the translation rate. Therefore, a better understanding of the codon usage pattern of the initiation translation region would shed light on the regulation of PRRSV gene expression.In this study, the codon usage in the translation initiation region and in the whole coding sequence was compared in PRRSV ORF1a and ORFs2-7. To investigate the potential role of codon usage in affecting the translation initiation rate, we established a codon usage model for PRRSV translation initiation region. We observed that some non-preferential codons are preferentially used in the translation initiation region in particular ORFs. Although some positions vary with codons, they intend to use codons with negative CUB. Furthermore, our model of codon usage showed that the conserved pattern of CUB is not directly consensus with the conserved sequence, but shaped under the translation selection.The non-variation pattern with negative CUB in the PRRSV translation initiation region scanned by ribosomes is considered the rate-limiting step in the translation process. Nidovirales of family Arteriviridae [Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes serious disease in swine populations with a series of clinical consequences, such as high mortality, reproductive failure, post-weaning pneumonia and growth reduction ,2. Basediviridae ,9. The Piviridae -13. Despiviridae ,14. Theriviridae -19. Moreiviridae .It is generally considered that the alternative synonymous codons are not used with equal frequencies among organisms, and the codon usage pattern plays a role in genes expressed at higher levels -30. Jacqhttp://www.ncbi.nlm.nih.gov/Genbank/ and the synonymous codon usage values (SCUV) for this virus were reported previously [st to the 50th residue) of ORF1a, ORF2, ORF3, ORF4, ORF5, ORF6 and ORF7 were used as targets for alignment analysis respectively.The 13 complete RNA sequences of PRRSV were downloaded from the National Center for Biotechnology Information (NCBI) eviously . Multipl0 = 1.00) for the development of serotype-specific codon usage [To calculate CUB, it is supposed that statistically equal and random usage of all available synonymous codons was the \"neutral point\" /(n/N), represents the relative abundance for a particular codon in the translation initiation region. ni represents the total number of a particular codon within the 1st to ith amino acids, Ni represents the total number of corresponding amino acid in the 1st to ith amino acid ones, n is the total number of a certain codon within the whole coding sequence, and N is the total number of corresponding amino acids within the whole coding sequence. When R value is equal to 1.00, it means that the frequency of this codon in the target region is equal to the frequency of this codon in the whole coding sequence; when R value is lower than zero, it implies that the frequency of this codon in the target region is lower than that of the whole coding sequence; when R value is higher than zero, it suggests that the frequency of this codon is higher than that of the whole coding sequence.We analyzed the codon usage characteristics of the translation initiation region depending on R values for codons of the target positions.To substantiate the characteristics of codon usage for positions with negative CUB in the target regions, we analyzed the target positions depending on the data, (i) the variations of codons and amino acids, (ii) The consensus amino acid sequence is based on the comparison of the strains in previous study . The posThe bars of all positions in the translation initiation region represented the CUB degree Figure . AlthougThe various extents of the conserved pattern of codon usage for their positions in PRRSV ORFs suggest that CUB associated with these positions might modulate the corresponding gene expression.R value for each codon was calculated and listed in Table R value indicated more preferential usage in the translation initiation site than that of the whole coding sequence. ij CUBvalue for each codon was listed in Table The R value for the codons with negative CUB vary compared with R = 1.00. However, some target positions contain the codons with negative CUB and R values > 1.00, suggesting that some new characteristics might influence the translation efficiency of the corresponding coding sequence. In translation initiation region of ORF1a, the non-preferential codons are preferentially used in the 4th (US and EU serotypes), 9th (US), 12th (EU), 19th (US), the 22nd (US and EU), 27th (US), 31st (US and EU) and 40th (US), while some non-preferential codons, which have R value < 1.00 or R value > 1.00, exist in the 16th (EU) and 30th (US and EU) positions. For ORF2, the non-preferential codons are more preferentially used in the 7th (EU), 8th (EU), 9th (EU), 11th (US), 20th (EU), 27th (EU), 30th (US), 33rd (US), 40th (EU), 43rd (EU), 44th (US) and 48th (EU) positions, while some non-preferential codons with R value > 1.00 or R value < 1.00 exist in the 12th (US) position. For ORF3, non-preferential codons exist in the 4th (US), 13th (US and EU), 17th (EU), 26th (US and EU), 31st (US and EU), 32nd (EU) and 37th (US) positions, while the non-preferential codons with R value > 1.00 or R value < 1.00 are used in the 5th (EU), 6th (US and EU), 7th (US), 11th (US and EU),16th (US) and 43rd (EU) positions. For ORF4, the non-preferential codons with R value > 1.00 are used in the 3rd (US and EU), 7th (US and EU), 20th (US and EU), 27th (US and EU), 28th (US and EU), 29th (US and EU), 38th (EU),40th (US and EU), 41st (US), 44th (EU) and 49th (US and EU), while some non-preferential nodons with R value > 1.00 or R value < 1.00 are used in the 31st (EU) position. For ORF5, the non-preferential nodons with R value > 1.00 are used in the 9th (EU), 12th (US), 14th (EU), 22nd (US) 23rd (US), 32nd (US), 36th (US), 39th (EU), 40th (EU), 44th (EU), 48th (EU) and 49th (EU), while non-preferential codon with R value > 1.00 or R value > 1.00 are used in the 8th (US), 24th (US), 46th (US) and 47th (US) positions. For ORF6, the non-preferential codons are used in the 3rd (US), 4th (EU), 7th (US), 13th (US), 14th (EU), 15th (EU), 19th (EU), 21st (US), 22nd (EU), 24th (EU), 26th (EU), 27th (US), 30th (EU), 31st (EU), 32nd (US), 37th (US), 40th (US), 45th (EU) and 48th (EU) positions, while some non-preferential codon are used in the 2nd (EU), 5th (US and EU), 46th (US) and 50th (US) positions. For ORF7, the non-preferential codons are chosen in the 11th (US), 32nd (US), 40th (US and EU), 41st (US), 43rd (EU), 44th (EU), 48th (US) and 50th (US) positions, while some non-preferential codon are used in the 3rd (US), 24th (EU), 25th (EU) and 35th (US) positions. The rest positions with negative CUB do not arise from the existence of non-preferential codons but contain some preferential codons (CUB > 0), implying that these positions do not affect the efficiency of gene translation. The degeneracy of the genetic code enables the same amino acid sequences to be encoded and translated in different ways. However, the synonymous codon usage is not purely random.The positions with negative CUB do not always use the codons with negative CUB, and the Drosophila species, suggesting that translation selection favors the conserved pattern of synonymous codon usage to enhance the accuracy of gene expression [CAT product [RNA virus possesses high mutation rates and therefore virus populations exist as dynamic and complex mutant distributions -41. Howepression . A lot opression . Non-unipression -52. Frompression . Howeverpression . Once a pression ,54-58. Kpression . Lavner pression . A relatpression ,61-65. Tpression ,67. Our pression ,63,64,68 product , the vie product . When th product ,71.In summary, the conserved non-preferential codons in the translation initiation region have a high relationship with the regulation of gene expression. And the conserved codons with negative CUB are preferentially used in the initial region, which may be explained by the minor codon modulator hypothesis and the translation selection. These codons within this critical region might play a negative role in regulation of gene expression.PRRSV: Porcine reproductive and respitatory syndrome virus; SCUV: synonymous codon usage values; CUB: codon usage bias; US: Northern American isolate; EU: European isolate.The authors declare that they have no competing interests.JHS and XXM carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript. YLH, JDL and XSM participated in the sequence alignment. YXD and XNL participated in the design of the study and performed the statistical analysis. XPC conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript."} +{"text": "Correction to: British Journal of Cancer (2012) 106, 1453\u20131459; doi:10.1038/bjc.2012.98In revision of the above paper during the proofing and correction process, an earlier version of Figure 3 was resupplied for publication and, subsequently, published in error. The authors and publishers apologise for this mistake.The correct"} +{"text": "DNA RESEARCH 21, 53\u201368, (2014); doi:10.1093/dnares/dst040B. oleracea Repeat number: the 3 should be 12. The corrected part of the table is given below.There was an error in the first three rows of Table"} +{"text": "A reference was omitted from the reference list during the production process. There reference is: 53. Middleton FA, Strick PL (1994) Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function. Science 266: 458-461.In place of reference 53, some erroneous formatting text was published in the PDF."} +{"text": "A funding organization for the second author, Claudio Eglueta, was incorrectly omitted from the Funding Statement. The Funding Statement should read: \"This work was supported by a DFG grant to NK and the VW-Foundation to CE. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.\"In addition, affiliation number 2 for the second author is incorrect. The correct affiliation number 2 is: Institut f\u00fcr Physiologie I, Albert-Ludwigs-Universit\u00e4t, Freiburg, Germany.In addition, all Supplementary Figure files are missing in both hyperlink and thumbnail format. The Supplementary Figures can be viewed at the following links, as indicated:Figure S1: Click here for additional data file.Figure S2: Click here for additional data file.Figure S3: Click here for additional data file.Figure S4: Click here for additional data file.Figure S5: Click here for additional data file.Figure S6: Click here for additional data file.Figure S7: Click here for additional data file.Figure S8: Click here for additional data file."} +{"text": "Correction to: British Journal of Cancer (2012) 104, 1482\u20131486; doi:10.1038/bjc.2011.114After publication, it was noted that the dose category labels contained in The full, correct"} +{"text": "The classical symptoms of porcine epidemic diarrhea (PED) are acute diarrhea and dehydration. The isolated porcine epidemic diarrhea virus (PEDV) CH/GDGZ/2012 strain was obtained from the feces of diseased pigs in 2012 in southern China. We report the complete genome sequence of strain CH/GDGZ/2012, which might be useful for better understanding the molecular characteristics of this virus. Alphacoronavirus, the family Coronaviridae, and the order Nidovirales (Porcine epidemic diarrhea virus (PEDV), which is an enveloped, positive-sense, single-stranded RNA virus, is classified as a member of the genus ovirales , 2.The whole genome of the PEDV strain CH/GDGZ/2012 was amplified by 21 sets of primers and clonThe complete genome sequence of CH/GDGZ/2012 exhibits 96.6%, 97.4%, 97.9%, and 97.0% nucleotide homologies with the genomes of PEDV strains CV777, DR13, CH/FJND-3/2011, and CH/S, respectively . SimilarThese data may be useful for analyses of the epidemiology and evolutionary characteristics of PEDVs in southern China.KF384500.The complete genome sequence of PEDV CH/GDGZ/2012 strain has been deposited in GenBank under the accession no."} +{"text": "In Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease by Samantha MaWhinney et al., an error occurred in the list of references. Missing from the list is reference no. 36: Belay ED, Maddox RA, Gambetti P, Schonberger LB. Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob disease in the United States. Neurology. 2003;60:176\u201381.http://wwwnc.cdc.gov/eid/article/12/10/06-0019_article.htmThe corrected list of references appears in the online article at We regret any confusion this error may have caused."} +{"text": "There was an error in the citation in the online version of the article. The correct citation is \"Bouillard K, Nordez A, Hug F (2011) Estimation of Individual Muscle Force Using Elastography. PLoS ONE 6(12): e29261. doi:10.1371/journal.pone.0029261\""} +{"text": "There was an error in the name of the fourth author.The correct author name is: Nickolay V. BukoreshtlievThe correct citation is: Modulevsky DJ, Tremblay D, Gullekson C, Bukoreshtliev NV, Pelling AE (2012) The Physical Interaction of Myoblasts with the Microenvironment during Remodeling of the Cytoarchitecture. PLoS ONE 7(9): e45329. doi:10.1371/journal.pone.0045329"} +{"text": "The correct name of the second author is: Bashir AhmadThe correct citation is: Noreen S, Ahmad B, Hayat T (2013) Mixed Convection Flow of Nanofluid in Presence of an Inclined Magnetic Field. PLoS ONE 8(9): e73248. doi:10.1371/journal.pone.0073248The correct version of the grant number in the first sentence of the Funding statement should be: 25-130/1433 HiCi"} +{"text": "The name of the first author was listed incorrectly. The correct name is: Adzemovic MV. The correct citation is: Adzemovic MZ, Zeitelhofer M, Eriksson U, Olsson T, Nilsson I (2013) Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response. PLoS ONE 8(2): e56586. doi:10.1371/journal.pone.0056586. The correct abbreviation in Contributions is: MZA."} +{"text": "The name of the third author is incorrect. The correct name is: Bradley S. Peterson. The correct citation is: Hu S, Xu D, Peterson BS, Wang Q, He X, et al. (2013) Association of Cerebral Networks in Resting State with Sexual Preference of Homosexual Men: A Study of Regional Homogeneity and Functional Connectivity. PLoS ONE 8(3): e59426. The correct abbreviation in Contributions is: BSP."} +{"text": "The name of the first author was spelled incorrectly. The correct name is: Gesham Magombedze.In addition, the word \"Evaluation\" was spelled incorrectly in the article title. The correct title is: Evaluation of the \"Iceberg Phenomenon\" in Johne's Disease through Mathematical Modelling.The correct citation is: Magombedze G, Ngonghala CN, Lanzas C (2013) Evaluation of the \u201cIceberg Phenomenon\u201d in Johne's Disease through Mathematical Modelling. PLoS ONE 8(10): e76636. doi:10.1371/journal.pone.0076636.In addition, the number of the grant from the National Science Foundation is incorrect. The correct grant number is: NSF Award # EF-0832858."} +{"text": "Isolona and Monodora (Annonaceae). Both these genera, with 20 and 14 species, respectively, are widely distributed in African TRFs, with a few species occurring in slightly less humid regions such as in East Africa.The tropical rain forests (TRF) of Africa are the second largest block of this biome after the Amazon and exhibit high levels of plant endemism and diversity. Two main hypotheses have been advanced to explain speciation processes that have led to this high level of biodiversity: allopatric speciation linked to geographic isolation and ecological speciation linked to ecological gradients. Both these hypotheses rely on ecology: in the former conservation of ecological niches through time is implied, while in the latter adaptation via selection to alternative ecological niches would be a prerequisite. Here, we investigate the role of ecology in explaining present day species diversity in African TRF using a species level phylogeny and ecological niche modeling of two predominantly restricted TRF tree genera, A total of 11 sister species pairs were identified most of them occurring in allopatry or with little geographical overlap. Our results provide a mixed answer on the role of ecology in speciation. Although no sister species have identical niches, just under half of the tests suggest that sister species do have more similar niches than expected by chance. PCA analyses also support little ecological differences between sister species. Most speciation events within both genera predate the Pleistocene, occurring during the Late Miocene and Pliocene periods.Isolona and Monodora at the scale analyzed here. This is consistent with the geographical speciation model for TRF diversification. These results contrast to other studies for non-TRF plant species where ecological speciation was found to be an important factor of diversification. The Pliocene period appears to be a vital time in the generation of African TRF diversity, whereas Pleistocene climatic fluctuations have had a smaller role on speciation than previously thought.Ecology is almost always involved in speciation, however, it would seem to have had a little role in species generation within Isolona, Monodora, AnnonaceaeEcological niche modeling, species level phylogeny, ecological speciation, African tropics, The tropical rain forest (TRF) biome covers just ~7% of land but harbors over half of the planet's terrestrial biodiversity. The TRF of Africa represents the second largest extent of this biome after the Amazon basin, and contains high levels of species diversity and especially endemicity . Two maiUnderstanding the evolutionary processes responsible for high species richness of TRF has been a major focus of evolutionary biology , althougNew developments in ecological niche modeling (ENM) or species distribution modeling have provided important advances in the understanding of species distribution , as wellIsolona and Monodora (Annonaceae). Both genera contain small to large trees largely distributed across the African rain forests from West/Central Africa to East Africa. A recent monograph of both genera provides information about species delimitation as well as their distribution . In oner et al. ,29 proviMean divergence ages Table for all Isolona capuronii (1), I. pleurocarpa (7), Monodora carolinae (7), M. globiflora (6), M. hastipetala (4) and M. stenopetala (6), all being rare or localized species. Analysis of the variation of each bioclim variable between species underlines important ecological characteristics within and between species of each genus. For Isolona, differences between East and West/Central species were few , higher temperature seasonality (BC4) and lower annual precipitation (BC12) as well as other related variables such as BC13, BC14, BC16, BC17 and BC19 on all 19 bioclim variables and significance between principal components were tested under Mann-Whitney U test. Together, the first and second components explained between 59% and 87% of the variation among the 19 bioclim variables. The directionality of the loadings for components 1 and 2 were quite variable, Figures and 5 buMonodora laurentii within M. myristica; M. hastipetala within M. junodii; Isolona cooperi within I. campanulata; 2) species that overlapped for part of their variation ; 3) species with clearly separated ecological space, which was found in just one species pair: Monodora carolinae /M. stenopetala. For most comparisons one to two PC axes were not significantly different between species pairs Species with narrower distributions were included within the environmental variation of a more widely distributed species (for example Monodora species) no standard deviation (SD) was calculated, even though the respective AUCs were high, because the number of total samples was too low (for species with occurrence points less than 8 only one training point can be used from which the SD cannot be estimated). Although several species in this study exhibited low sample sizes, the resulting AUCs indicate that meaningful models have been produced is reported in Table S1. Response curves and variable importance were examined; however no general trends or consistent suite of variables were identified as the important factors for species' distributions.Monodora hastipetala /M. junodii, and all four tests for Isolona heinsenii /I. linearis.Potential distribution generated under ENM using Maxent between selected sister species are presented in Figures K of Blomberg et al. . Also, than 10 .Afromomum . A secondary calibration point was used, with the crown node of Isolona and Monodora set to 14.9 Ma (95% highest posterior density (HPD) 9.4-21). A similar age (14.4 (95% HPD 10.2-18.7) for this node was also found with a larger sampling of Annonaceae genera and with an updated fossil calibration hypothesis [For this analysis we used the chronogram of Couvreur et al. which inpothesis .Isolona and 737 for Monodora (Table S1).Locality data were compiled from Couvreur and reprAn estimate of the known geographic range for each species was produced in ArcGIS v 9.3 using a \"buffer\" approach. This method creates a buffer radius around each collection point for each species. Overlapping buffers for each species pair are then fused and the range overlap is calculated. Several other approaches can be used such as the \"quadrat\" [e.g. ]: the dihttp://www.worldclim.org at 30 arc seconds resolution [Using the 19 bioclim variables Table from httsolution , a set oEnvironmental niches were compared between sister species using Principal Component Analysis (PCA) on all 19 bioclim variables. Statistical tests between groups have generally relied on AMOVA or MANOVA methods either between the principal components of the PCA ,48 or onM. hastipetala (see below). Ecological niche models were generated using the maximum entropy method, Maxent version 3.3 [Ecological niche modeling was used in order to summarize the climatic tolerances of the sampled species, except for sion 3.3 . This ission 3.3 ,70,71. Msion 3.3 .Isolona and Monodora (below 12\u00b051'N and above 28\u00b07'S); latitudinal boundaries which roughly coincide with limits of the suitable land cover types for these species. The 19 bioclim layers and an elevation layer , niche models we unable to be generated in Maxent due to the low number of unique occurrence localities (4). Therefore, the known geographic range was used for niche similarity tests, rather than the Maxent output. The software quantifies niche similarity using two metrics: D [I, a measure derived from Hellinger distance. These metrics are calculated by comparing the estimated niche suitability values from individual pixels in Maxent model outputs, where those outputs have first been normalized such that all predicted suitability values in the geographic space sum to 1 [For all sister species pairs, we compared the Maxent outputs using the software ENMtools followintrics: D , and I, sum to 1 . Althougsum to 1 .D and I values were calculated for each of the pseudoreplicate models. The distribution of these similarity values was then compared to the D and I values calculated from the actual niche models for that species pair in the niche overlap test. This method tests the null hypothesis that the two species have equivalent ecological niches and is expected to be met only if both species tolerate exactly the same environmental conditions and have an equivalent set of environmental condition available to them [The niche identity test compares niche models generated with actual occurrence localities to pseudoreplicate models generated with points randomly selected from a pool of actual occurrence localities to determine if species pairs have equivalent niches. For the identity tests, 100 pseudoreplicates were created from the pooled localities for each pair of sister species and to them .D and I values were calculated for each pseudoreplicate model and the distribution of these values was compared to the niche overlap values calculated for the actual data. This method tests the null hypothesis that calculated niche overlap between two species is explained by differences in their environmental background. The null hypothesis is rejected if the calculated niche overlap falls outside the 95% confidence interval for the distribution of pseudoreplicate model values.The background similarity test compares differences in the environmental background of species pairs to determine if the two species are more or less similar than expected by chance. For each species pair, the niche model for the focal species is compared to a series of pseudoreplicate models generated by randomly sampling the 'background' (geographic range) of its sister species . In the K of Blomberg et al. [The phylogenetic signal for eacg et al. . The QVIg et al. . This apK is used to quantify the \"amount of phylogenetic signal relative to the amount expected for a character undergoing Brownian motion evolution along the specified topology and branch lengths\" [[K < 1 indicating low phylogenetic dependence of the variable and K > 1 indicating high phylogenetic signal of the variable. When K = 1, the variable exhibits the phylogenetic signal expected under the Brownian motion model (e.g. the null model). K was estimated for each of the 19 bioclim variables using the multiPhylosignal command in the picante (ver. 1.3) [engths\" [, page 73engths\" [. The staer. 1.3) R packagphyloclim ver. 0.8.1 [phyloclim. For each genus, a total of 1000 simulations were undertaken.We also tested for phylogenetic signal of niche differentiation by using an adaptation of the age-range correlation method of in whichr. 0.8.1 to generr. 0.8.1 as impleTLPC conceived and coordinated the study, participated in its design, undertook part of the statistical analyses and drafted the manuscript. HPM participated in the design of the study, performed part of the statistical and all GIS analyses and helped draft the manuscript. JJW participated significantly in the production of the data. LWC participated in the conception of the study. All authors read and approved the final manuscript.IsolonaVariation of bioclim variables BC1-6 for . Indicates the variation of bioclim variables BC1 to 6 for all sampled species in Isolona. West/Central African species: 1: Isolona congolana; 2: I. hexaloba; 3: I. pleurocarpa; 4: I. zenkeri; 5: I. campanulata; 6: I. cooperi; 7: I. dewevrei; 8: I. thonneri; 9: I. cauliflora. East African species: 10: I. heinsenii; 11: I. linearis. Malagasy species: 12: I. capuroni; 13: I. ghesquierei; 14: I. perrierii.Click here for fileIsolonaVariation of bioclim variables BC7-12 for . Indicates the variation of bioclim variables BC7 to 12 for all sampled species in Isolona. West/Central African species: 1: Isolona congolana; 2: I. hexaloba; 3: I. pleurocarpa; 4: I. zenkeri; 5: I. campanulata; 6: I. cooperi; 7: I. dewevrei; 8: I. thonneri; 9: I. cauliflora. East African species: 10: I. heinsenii; 11: I. linearis. Malagasy species: 12: I. capuroni; 13: I. ghesquierei; 14: I. perrierii.Click here for fileIsolonaVariation of bioclim variables BC13-18 for . Indicates the variation of bioclim variables BC7 to 12 for all sampled species in Isolona. West/Central African species: 1: Isolona congolana; 2: I. hexaloba; 3: I. pleurocarpa; 4: I. zenkeri; 5: I. campanulata; 6: I. cooperi; 7: I. dewevrei; 8: I. thonneri; 9: I. cauliflora. East African species: 10: I. heinsenii; 11: I. linearis. Malagasy species: 12: I. capuroni; 13: I. ghesquierei; 14: I. perrierii.Click here for fileIsolonaVariation of bioclim variable BC19 for . Indicates the variation of bioclim variable BC19 for all sampled species in Isolona. West/Central African species: 1: Isolona congolana; 2: I. hexaloba; 3: I. pleurocarpa; 4: I. zenkeri; 5: I. campanulata; 6: I. cooperi; 7: I. dewevrei; 8: I. thonneri; 9: I. cauliflora. East African species: 10: I. heinsenii; 11: I. linearis. Malagasy species: 12: I. capuroni; 13: I. ghesquierei; 14: I. perrierii.Click here for fileMonodoraVariation of bioclim variables BC1-6 for . Indicates the variation of bioclim variables BC1 to 6 for all sampled species in Monodora. West/Central African species 1: Monodora angolensis 2: M. crispata, 3: M. laurentii, 4: M. myristica, 5: M. tenuifolia, 6: M. undulata. East African species: 7: M. carolinae, 8: M. globiflora, 9: M. grandidieri, 10: M. hastipetala, 11: M. junodii, 12: M. minor, 13: M. stenopetala.Click here for fileMonodoraVariation of bioclim variables BC7-12 for . Indicates the variation of bioclim variables BC7 to 12 for all sampled species in Monodora. West/Central African species 1: Monodora angolensis 2: M. crispata, 3: M. laurentii, 4: M. myristica, 5: M. tenuifolia, 6: M. undulata. East African species: 7: M. carolinae, 8: M. globiflora, 9: M. grandidieri, 10: M. hastipetala, 11: M. junodii, 12: M. minor, 13: M. stenopetala.Click here for fileMonodoraVariation of bioclim variables BC13-18 for . Indicates the variation of bioclim variables BC7 to 12 for all sampled species in Monodora. West/Central African species 1: Monodora angolensis 2: M. crispata, 3: M. laurentii, 4: M. myristica, 5: M. tenuifolia, 6: M. undulata. East African species: 7: M. carolinae, 8: M. globiflora, 9: M. grandidieri, 10: M. hastipetala, 11: M. junodii, 12: M. minor, 13: M. stenopetala.Click here for fileMonodoraVariation of bioclim variable BC19 for . Indicates the variation of bioclim variable BC19 for all sampled species in Monodora. West/Central African species 1: Monodora angolensis 2: M. crispata, 3: M. laurentii, 4: M. myristica, 5: M. tenuifolia, 6: M. undulata. East African species: 7: M. carolinae, 8: M. globiflora, 9: M. grandidieri, 10: M. hastipetala, 11: M. junodii, 12: M. minor, 13: M. stenopetala.Click here for fileSpecies values. Indicates the number of unique data points as well as several ENM parameters for each species sampled in the molecular phylogeny used to generate the ENM. Bold values indicate species for which there were fewer than 8 unique data points.Click here for fileIsolona speciesPotential distribution of . Shows the rest of the models generated for Isolona species.Click here for fileMonodora speciesPotential distribution of . Shows the rest of the models generated for Monodora species.Click here for fileMonodora and Isolona speciesPotential distribution of the two last . Shows the rest of the models generated for Monodora and Isolona species.Click here for fileIsolonaDistribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for fileIsolonaDistribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for fileIsolona (continue from sup file 1) and MonodoraDistribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for fileMonodora (continue from sup file 2)Distribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for fileMonodora (continue from sup file 3)Distribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for fileMonodora (continue from sup file 4)Distribution of species in . Shows the geographical location of all data points for each species used in this study.Click here for file"} +{"text": "Correction to:British Journal of Cancer (2011) 106, 133\u2013140; doi:10.1038/bjc.2011.504Upon publication of this paper earlier in Volume 106, the authors noticed an error in The authors would like to apologise for this error."} +{"text": "There was an error in the title of the article. The correct version of the title in the article is: Topographical Body Fat Distribution Links to Amino Acid and Lipid Metabolism in Healthy Obese WomenThe correct citation is: Martin F-PJ, Montoliu I, Collino S, Scherer M, Guy P, et al. (2013) Topographical Body Fat Distribution Links to Amino Acid and Lipid Metabolism in Healthy Obese Women. PLoS ONE 8(9): e73445. doi:10.1371/journal.pone.0073445"} +{"text": "Correction to: British Journal of Cancer (2010) 103, 1128\u20131135; doi:10.1038/sj.bjc.6605838During the final correction of the above paper prior to its publication in late 2010, an error was introduced in The publishers apologise for this mistake."} +{"text": "The middle initial is missing from the second author's name in the byline and citation. The correct spelling is: John S. DaviesThe correct citation is: Cleveland SB, Davies JS, McClure MA (2011) A Bioinformatics Approach to the Structure, Function, and Evolution of the Nucleoprotein of the Order Mononegavirales. PLoS ONE 6(5): e19275. doi:10.1371/journal.pone.0019275"} +{"text": "To the Editor:Sapovirus is the distinct genus within the family Caliciviridae; these viruses cause sporadic cases and outbreaks of gastroenteritis in humans worldwide . By using multiplex reverse transcription\u2013polymerase chain reaction (RT-PCR), 2 groups of diarrheal viruses were identified. The first group included astrovirus, norovirus, and sapovirus; the second group included rotavirus and adenovirus (http://sray.med.som.jhmi.edu/SCRoftware/simplot), the recombination site was identified at the polymerase-capsid junction. Before this junction, sequences of HU/5862/Osaka/JP and Sapporo/82 were highly homologous. However, homology between them was notably different after the junction, with a sudden drop in the identity for HU/5862/Osaka/JP. By using ClustalX, HU/5862/Osaka/JP shared a 96% identity in polymerase sequence and an 85% identity in capsid sequence with Sapporo/82. In contrast, homology was 99% in the capsid region between HU/5862/Osaka/JP and 8/DCC/Tokyo/JP/44. Since a polymerase sequence of 8/DCC/Tokyo/JP/44 was not available in GenBank because of the unsuccessful amplification, homology in the polymerase region between HU/5862/Osaka/JP and 8/DCC/Tokyo/JP/44 was unknown.The fecal specimen was positive for sapovirus. HU/5862/Osaka/JP clustered into the genogroup I genotype 8 (GI/8 the 8/DCC/Tokyo/JP/44 cluster) by usingAltogether, the findings underscored that HU/5862/Osaka/JP represented a novel, naturally occurring, recombinant sapovirus with GI/8 capsid and GI/1 polymerase. To determine whether the child was infected with this novel recombinant sapovirus or whether the novel recombinant sapovirus resulted from co-infection with 2 different viruses, Svppo (Sapporo/82-specific primer), Svdcc (8/DCC/Tokyo/JP/44-specific primer), and SLV5749 were used to amplify the capsid region (,Even though many molecular epidemiologic studies on sapovirus infection have been performed worldwide, reports documenting recombination in sapovirus are still limited. The first recombinant sapovirus identified was the Thai isolate Mc10 or the Japanese isolate C12 (In recent studies of sapovirus recombination, evidence for the location of the recombination event is lacking because of the distant geographic relationship of parent and progeny strains. HU/5862/Osaka/JP shared the closest sequences of polymerase and capsid with Sapporo/82 and 8/DCC/Tokyo/JP/44, respectively. Sapporo/82 was first isolated in 1982, and 8/DCC/Tokyo/JP/44 was isolated in 2000, both in Japan. Possibly, Sapporo/82 and 8/DCC/Tokyo/JP/44 were parental strains of HU/5862/Osaka/JP, and the event leading to the novel recombination might have occurred in Japan.The capsid region was used for genotype classification of sapovirus ("} +{"text": "The name of the second author was given incorrectly. The correct name is: Jean Michel Brunel. The correct citation is: Khelaifia S, Brunel JM, Drancourt M (2013) In-Vitro Archaeacidal Activity of Biocides against Human-Associated Archaea. PLoS ONE 8(5): e62738. doi:10.1371/journal.pone.0062738. The name is correctly reflected in the abbreviation in Contributions as it is."} +{"text": "The word \"Leishmaniasis\" is misspelled in the title. The correct title is: Monitoring Toxicity Associated with Parenteral Sodium Stibogluconate in the Day-Case Management of Returned Travellers with New World Cutaneous Leishmaniasis. The correct citation is: Wise ES, Armstrong MS, Watson J, Lockwood DN (2012) Monitoring Toxicity Associated with Parenteral Sodium Stibogluconate in the Day-Case Management of Returned Travellers with New World Cutaneous Leishmaniasis. PLoS Negl Trop Dis 6(6): e1688. doi:10.1371/journal.pntd.0001688"} +{"text": "The correct title and legend of Figure 2 presently appears with Figure 3. The correct, complete Figure 2 legend and title are:Time to resolution of viraemia.Kaplan \u2013 Meier survival analysis of time to resolution of plasma viraemia by treatment group (CQ or placebo) and population; A) Intention to treat population and B) Per Protocol population.doi:10.1371/journal.pntd.0000785.g003"} +{"text": "Acta Cryst. (2012), E68, m1025.Corrigendum to Acta Cryst. (2012), E68, m1025] is corrected.The author list in the paper by Mafud [ In the paper by Mafud (2012)"} +{"text": "Cryptococcus gattii, British Columbia, Canada, 1999\u20132007 . The article has been corrected online (www.cdc.gov/eid/content/16/2/251.htm).Some data were listed incorrectly in Table 1 and the text in the article Epidemiology of"} +{"text": "Correction to: British Journal of Cancer (2011) 104, 229\u2013234; doi:10.1038/sj.bjc.6606009Upon publication in early 2011, the authors noted the omission of an Acknowledgments section that they had intended to include. This is now included in full, below. The authors apologise for the original omission."} +{"text": "As a result of issues in the production process, there was an error in the name of the first author.The correct name of this author is: Leonardo Vieira NetoZAC1 and SSTR2 Are Downregulated in Non-Functioning Pituitary Adenomas but Not in somatotropinomas. PLoS ONE 8(10): e77406. doi:10.1371/journal.pone.0077406 The correct citation is: Vieira Neto L, Wildemberg LE, Colli LM, Kasuki L, Marques NV, et al. (2013)"} +{"text": "The word \"Protozoans\" is misspelled in the article title. The correct title is: On the Evolution of Hexose Transporters in Kinetoplastid Protozoans. The correct citation is: Pereira CA, Silber AM (2012) On the Evolution of Hexose Transporters in Kinetoplastid Protozoans. PLoS ONE 7(5): e36303. doi:10.1371/journal.pone.0036303"} +{"text": "There was a typographical error in the title and citation. The correct title is: Phenology of Scramble Polygyny in a Wild Population of Chrysomelid Beetles: The Opportunity for and the Strength of Sexual Selection. The correct citation is:Baena ML, Mac\u00edas-Ord\u00f3\u00f1ez R (2012) Phenology of Scramble Polygyny in a Wild Population of Chrysomelid Beetles: The Opportunity for and the Strength of Sexual Selection. PLoS ONE 7(6): e38315. doi:10.1371/journal.pone.0038315"} +{"text": "There was an error in the funding statement. The correct funding information is:http://www.cancerforskningsfond-umea.lions.se/), Ume\u00e5 University, Sweden (LP 09-1799). Funding for the Me-Can project was obtained from the World Cancer Research Fund (WCRF UK) (http://www.wcrf-uk.org/) for grant 2007/09 and from Wereld Kanker Onderzoek Fonds (WCRF NL) (http://www.wcrf.nl/) for grant R2010/247, as part of the WCRF International grant programme, and the Swedish Cancer Foundation (http://www.cancerfonden.se/sv/Information-in-English/)(2010/628). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.This study was supported by grants from Lion's Cancer Research Foundation ("} +{"text": "The word \"Level\" is misspelled in the article title. The correct title is: Associations between Perceived HIV Stigma and Quality of Life at the Dyadic Level: The Actor-Partner Interdependence Model. The correct citation is: Liu H, Xu Y, Lin X, Shi J, Chen S (2013) Associations between Perceived HIV Stigma and Quality of Life at the Dyadic Level: The Actor-Partner Interdependence Model. PLoS ONE 8(2): e55680. doi:10.1371/journal.pone.0055680"} +{"text": "Correction to: British Journal of Cancer (2011) 105, 682\u2013686; doi:10.1038/bjc.2011.276During the final editing of the above paper before its publication, errors were, unfortunately, introduced in equations 5 and 7. In both the equations, a minus sign had been deleted. The correct equations are now shown below.The authors and publishers apologise for any inconvenience this may have caused."} +{"text": "The name of the fourth author is incorrect. The correct name is: Masashi Kantake.The correct citation is: Jujo T, Sakao S, Tsukahara M, Kantake M, Maruoka M, et al. (2014) The Role of Matrix Metalloproteinase in the Intimal Sarcoma-Like Cells Derived from Endarterectomized Tissues from a Chronic Thromboembolic Pulmonary Hypertension Patient. PLoS ONE 9(1): e87489. doi:10.1371/journal.pone.0087489.The correct abbreviation of the fourth author's name in the Author Contributions statement is: MK."} +{"text": "There was an error in the article title. The correct title is: \"Testosterone Levels Are Negatively Associated with Fatherhood in Males, but Positively Related to Offspring Count in Fathers.\" The correct citation is: Pollet TV, Cobey KD, van der Meij L (2013) Testosterone Levels Are Negatively Associated with Fatherhood in Males, but Positively Related to Offspring Count in Fathers. PLoS ONE 8(4): e60018. doi:10.1371/journal.pone.0060018."} +{"text": "The name of the third author was incorrect. The correct name is: Thorhallur I Halldorsson.The correct citation is: Danielsen I, Granstr\u00f6m C, Halldorsson TI, Rytter D, Hammer Bech B, et al. (2013) Dietary Glycemic Index during Pregnancy Is Associated with Biomarkers of the Metabolic Syndrome in Offspring at Age 20 Years. PLoS ONE 8(5): e64887. doi:10.1371/journal.pone.0064887.The correct abbreviation in Contributions is: TIH."} +{"text": "Correction #1: Error in figure order. The images for Figures 7 and 8 were incorrectly switched. The image that appears as Figure 7 should be Figure 8, and the image that appears as Figure 8 should be Figure 7. The figure legends appear in the correct order.Correction #2: Error in Figure 1 legend.There is an error in the Figure 1 legend. The correct legend for Figure 1 is:1A and 1B: overlaid time courses of summarized microarray fluorescence for each yeast gene, as the of the mean-ratio , for the 0.7 h [11] and 5 h [10] period datasets, respectively. The bottom two panels show cluster averages for consensus and background clusters. The top panel shows the time courses of the dissolved O2 trace (DOT) in the culture medium in percent of the saturated concentration. Cluster colors and sizes (number of genes in each cluster) are given in the legend in Figure 1C. For clarity of visualization the time course data was normalized to a reference set that was selected for significant lack of oscillation . Individual time courses for each cluster are plotted in Figure S2. 1D: phase-phase plot comparing the phase-angles of all transcripts in the two experiments. The phase angles were shifted such that cluster A phase angles are just above 0\u00b0 in both datasets. Mapping back from frequency- to time-domain, we can locate the shifted phase angles of one cycle (0\u00b0 and 360\u00b0) in the time series plot , and use the same mapping in the top and right axes (in gray) of the phase-phase plot. The x- and y-extensions of each point scale with the transcript\u2019s scaled amplitude in the respective dataset, where the non-consensus clusters (lower case letters) have a smaller initial size. Dataset S1 provides raw summarized microarray intensities, and the clustering of all analyzed yeast genes.Correction #3: Errors in multiple URLs.There are several links in this article that are incorrect. The correct versions of these links are:The correct link found in the Genome Data Sources of the Discussion section is:http://www.tbi.univie.ac.at/~raim/data/2011/yeast/clusters/geneData.tar.gz [^] [^]The correct link found in the last paragraph of the Statistical DNA Profiles (SDP) section is:http://www.tbi.univie.ac.at/~raim/data/2011/yeast/clusters/geneData.tar.gz [^] [^]The correct links found in the Table S8 Supporting Information section are:http://www.tbi.univie.ac.at/~raim/data/2011/yeast/clusters/geneData.tar.gz [^] [^]andhttp://www.tbi.univie.ac.at/~raim/data/2011/yeast/clusters/ [^] [^]"} +{"text": "The third author's name is spelled incorrectly. The correct name is: Zainularifeen Abduljaleel. The correct citation is:Alanazi M, Pathan AAK, Abduljaleel Z, Shaik JP, Alabdulkarim HA, et al. (2013) Association between PARP-1 V762A Polymorphism and Breast Cancer Susceptibility in Saudi Population. PLoS ONE 8(12): e85541. doi:10.1371/journal.pone.0085541There is also an error in the second sentence of the Materials and Methods section. Patients included in the study had breast cancer, not cardiovascular disease. The correct sentence reads: These encompassed 99 patients with breast cancer and 96 healthy controls."} +{"text": "There was an error in the title of the article.Apostichopus japonicusThe correct title is: RNA-Seq Reveals Dynamic Changes of Gene Expression in Key Stages of Intestine Regeneration in the Sea Cucumber Apostichopus japonicus. PLoS ONE 8(8): e69441. doi:10.1371/journal.pone.0069441 The correct citation is: Sun L, Yang H, Chen M, Ma D, Lin C (2013) RNA-Seq Reveals Dynamic Changes of Gene Expression in Key Stages of Intestine Regeneration in the Sea Cucumber"} +{"text": "Corrigenda for five articles. Acta Cryst. (2011a), E67, m1496; Acta Cryst. (2011b), E67, m1497; Acta Cryst. (2011c), E67, m1498] and Chiririwa & Muller .The affiliation of one of the authors and a source of funding are both added in the following papers: Chiririwa & Meijboom ["} +{"text": "BN82451 is patented (P\u00e4tent portfolio made up of different family of patents: Novel of 2-(iminomethyl)amino-phenyl derivatives intermidiates; e.g. US6586454; 5-membered heterocycle derivatives: e.g. WO01/26656, WO2005/035510; Use of thiazole derivatives for preparing a medicament for protecting the mitochondria: e.g. WO 03/009843; Thiazoles derivatives for the treatment of dyskinesia: e.g. WO2007/006942 and Thiazoles derivatives for the treatment of restless legs syndrome: WO2007/006941) and is being developed by Ipsen. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.There is an error in the Competing Interests statement. The correct statement is: Co-authors Auguet M, Chabrier PE, Spinnewyn B are employed by IPSEN Innovation. The research reported in this manuscript has been funded in part by IPSEN Innovation ("} +{"text": "There was an error in the funding statement. The correct funding information is:This research is supported by UM High Impact Research Grant UM-MOHE UM.C/HIR/MOHE/08 from the Ministry of Higher Education Malaysia and High Impact Research Grant UM.C/625/1/HIR/003/1 from the University of Malaya. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."} +{"text": "MSM authors meant to be a check-list to adhere to in their submissions.This is a brief write-up for While writing, do look into the following:Abstract at the beginning [100-150 words].Add an Key Words after Abstract [4-6 key words from the text], separated by semi-colons.Add Author Affiliations, Correspondence address, and email id below Key Words.Add Introduction. 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Where a book has been published by 2 publishersFlew A., , A Dictionary of Philosophy. London: Pan Books in association with The Macmillan Press.iv.j. Where a book is published by one but reprinted by anotherJames W., (1890/1999), The Principles of Psychology. Ch 9. (2 vols.). New York: Henry Holt .For Web References:National Institute of Mental Health, (2011), Schizophrenia. Available at http://www.nimh.nih.gov/health/topics/schizophrenia/index.shtml [Accessed 20 Dec 2010.].For News Paper/Magazine Articles:Harris G., (2004), As doctor writes prescription, drug company writes a check, New York Timesc, June 27, A1.Personal communicationsPersonal communication may not ordinarily be quoted as a reference. If at all done, it should be with the written permission of the communicator.Copyright21. Mens Sana Monographs. 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For a typical paper, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2009;volume=7;issue=1;spage=10;epage=19;aulast=ChadwickAnd/orhttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2010;volume=8;issue=1;spage=30;epage=51;aulast=VarmaFor a typical editorial, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2010;volume=8;issue=1;spage=6;epage=16;aulast=SchwartzFor a typical Book review, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2010;volume=8;issue=1;spage=146;epage=150;aulast=AndradeMSM Poem, seeFor typical http://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=277;epage=278;aulast=BrennerFor a typical Journalology article, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=226;epage=236;aulast=HoeyFor a typical article in the Looking Glass, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=41;epage=47;aulast=GilmanFor a typical article in Reflections, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=135;epage=145;aulast=NarlikarFor a typical article in Musings, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=131;epage=134;aulast=ArnoldFor typical obituary, seehttp://www.msmonographs.org/article.asp?issn=0973-1229;year=2008;volume=6;issue=1;spage=281;epage=284;aulast=RavehBest wishes."} +{"text": "The name of the third author was given incorrectly. The correct name is: Duolao Wang. The correct citation is: Gao W, Yan H, Wang D, Dang S, Pei L (2013) Severity of Anemia among Children under 36 Months Old in Rural Western China. PLoS ONE 8(4): e62883. doi:10.1371/journal.pone.0062883.In addition, the first sentence in Contributions was incorrectly separated into two sentences. The correct sentence is: \"Conceived and designed the experiments: WG SD LP.\""} +{"text": "LCH is the rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes. The clinical presentation of LCH may occur in multiple organs: bone, skin, lymph nodes or pituitary gland, but clinical presentation of LCH rarely occurs in multiple endocrine systems.We presented a special case who was diagnosed with LCH and presentation of LCH occurred in multiple systems: pituitary gland, thyroid, adrenal gland.A 11 years old girl was hospitalized for lump on the neck. Past history: one year ago, she was diagnosed with autoimmune polyendocrine syndromes and treated with hormone replacement . Physical examination showed: she had a swollen lump on her neck, she had a temperature of 38\u00b0 C. She had no polyuria, no polydipsia. Her height was 141cm (-0.29 SD); her weight was 37 kg; her BMI was 18.5 (50th \u2013 70th) .She had normal growth velocity and normal pubertal development. Laboratory evaluation revealed : WBC : 10.3 \u00d7 109 /l ; CRP : 105.78 mg/l ; serum cortisol at 8 a.m : 16.3 nmol/l ; T3 : 1.8 nmol/l , T4 : 135.9 nmol/l , TSH : 0.002 mUI/ml ; blood osmotic pressure : 279 moms/kg, urinary osmotic pressure : 127 mosm/kg; plasma glucose level and electrolyte were normal. An MRI of brain showed: thickened pituitary stalk. A biopsy of the lump on her neck showed: features of Langerhans Cell; skeletal and long bone radiograph showed no osteolytic lesion.She was treated with hormone replacement and chemotherapy.Written informed consent was obtained from the patient's parent or guardian for publication of this Case report (and any accompanying images). A copy of the written consent is available for review by the Editor-in-Chief of this journal."} +{"text": "The correct citation is: Llibre JM, Raffi F, Moyle G, Behrens G, Bouee S, Reilly G, et al. (2016) An Indirect Comparison of Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate and Abacavir/Lamivudine + Dolutegravir in Initial Therapy. PLoS ONE 11(5): e0155406. doi:The Abstract is missing a sentence at the end of the \u201cResults\u201d subheading. The additional sentence is: In an indirect comparison, we found no statistically significant differences in efficacy, serious adverse events, drug related adverse events, drug related serious adverse events, death or selection of viral resistance between E/C/F/TDF and ABC/3TC + DTG in initial therapy.There are numerical errors in the second sentence of the first paragraph in the Results section under the subheading \u201cVirological failure and resistance.\u201d The correct sentence is: In GS-US-236-0102, 7% of patients on E/C/F/TDF and 10% of subjects on EFV/FTC/TDF were considered virological failures at week 144, while in SINGLE, rates were 9% and 8% for ABC/3TC + DTG and EFV/FTC/TDF, respectively.There are errors in the first two sentences of the Conclusion. The correct sentences are: With the limitation that we did not perform a systematic review we can conclude that: The indirect efficacy comparisons do not show significant differences between E/C/F/TDF and ABC/3TC + DTG. For efficacy, the difference between both regimens at week 48, 96 and 144 were small and not statistically significant; Resistance and all safety results (except for discontinuation due adverse events) also do not show significant differences between the 2 regimens.The captions for Figs 3, 4 and 5 appear incorrectly in the published article. Please see Figs"} +{"text": "Nature Communications6: Article number: 10106 10.1038/ncomms10106 (2015); Published: 12032015; Updated: 03032016The original version of this Article contained an error in the spelling of the author Jennifer S. Stevens, which was incorrectly given as Jennifer J. Stevens. Furthermore, in Fig. 5, the titles for panels a and b were inadvertently switched. Both of these errors have now been corrected in the PDF and HTML versions of the Article."} +{"text": "Correction to:Cell Discovery (2015) 1, 15005; doi:10.1038/celldisc.2015.5; published online 19 May 2015During web production, there was an error in Supplementary information: Supplementary Tables S1 and S2 were omitted. The files are now installed in the online version of the paper.We apologize for any inconvenience that may have been caused by this error."} +{"text": "February 7 is National Black HIV/AIDS Awareness Day, an observance intended to raise awareness of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and encourage action, such as HIV testing, to reduce the disproportionate impact of HIV/AIDS on blacks or African Americans in the United States. Two of the three goals of the National HIV/AIDS Strategy are to reduce new HIV infections and HIV disparities .Compared with other races and ethnicities, blacks had the highest HIV incidence in 2010, with an estimated rate of 68.9 per 100,000 population, which was nearly eight times the estimated rate of 8.7 among whites . Among bhttp://www.cdc.gov/features/blackhivaidsawareness. Information about blacks and HIV/AIDS is available at http://www.cdc.gov/hiv/risk/racialethnic/aa/index.html.Information about National Black HIV/AIDS Awareness Day is available at"} +{"text": "Regarding the paper titled: \u2018Empirical evidence of the effect of school gathering on the dynamics of dengue epidemics\u2019 by Carlos M Hern\u00e1ndez-Su\u00e1rez and Oliver Mendoza-CanoCitation: Glob Health Action 2016, 9: 28026 - http://dx.doi.org/10.3402/gha.v9.28026Published in Global Health Action 06 Jan 2016. In the Results and Discussion section, in Figure 5, the legend reads \u201cCleaning campaign in 2006 started at week 22.\u201d it should say \u201cCleaning campaign in 2007 started at week 22\u201d.The legend currently reads:Fig. 5. Reported accumulated dengue incidence in the state of Colima for the years 2006\u20132008. Source: National Center for Epidemic Surveillance. The beginning of the school year is at week 33. Cleaning campaign in 2006 started at week 22. Source: CENAVECE (12).The legend should read:Fig. 5. Reported accumulated dengue incidence in the state of Colima for the years 2006\u20132008. Source: National Center for Epidemic Surveillance. The beginning of the school year is at week 33. Cleaning campaign in 2007 started at week 22. Source: CENAVECE (12)."} +{"text": "Scientific Reports5: Article number: 13746; 10.1038/srep13746published online 09082015; updated: 01272016The Acknowledgements section in this Article is incomplete.\u201cThe study has been supported by EU (Marie Curie FP7 project #269140), Academy of Finland (grant #288151 and #265015), EPSRC (grant EP/M029042/1), and Russian Science Foundation (grant no. 14-22-00136). P.G.K. thanks Ministry of Education and Science of the Russian Federation (Grant No. 14.Z50.31.0009). Authors are grateful to Amin Abdolvand for valuable comments on the manuscript.\u201dshould read:http://dx.doi.org/10.5258/SOTON/384152).\u201d\u201cThe study has been supported by EU (Marie Curie FP7 project #269140), Academy of Finland (grant #288151 and #265015), EPSRC (grant EP/M029042/1), and Russian Science Foundation (grant no. 14-22-00136). P.G.K. thanks Ministry of Education and Science of the Russian Federation (Grant No. 14.Z50.31.0009). Authors are grateful to Amin Abdolvand for valuable comments on the manuscript. The data for this work is accessible through the University of Southampton Institutional Research Repository ("} +{"text": "The publisher apologizes for the error. The correct name is: Eva C. Arnspang. The correct citation for the original article is: Arnspang EC, Kulatunga P, Lagerholm BC (2012) A Single Molecule Investigation of the Photostability of Quantum Dots. PLoS ONE 7(8): e44355. doi: 10.1371/journal.pone.0044355.The first author\u2019s name in the text of the Correction notice published on April 9"} +{"text": "This article was republished on May 21, 2014, to correct an error in the title of the article.The title should read:Darevskia dahliClonal Diversity and Clone Formation in the Parthenogenetic Caucasian Rock Lizard The citation should read:Darevskia dahli. PLoS ONE 9(3): e91674. doi:10.1371/journal.pone.0091674Vergun AA, Martirosyan IA, Semyenova SK, Omelchenko AV, Petrosyan VG, et al. (2014) Clonal Diversity and Clone Formation in the Parthenogenetic Caucasian Rock Lizard Please download this article again to view the correct version. The originally published, uncorrected article and republished, corrected article are provided here for reference.File S1Originally published, uncorrected article.(PDF)Click here for additional data file.File S2Republished corrected article.(PDF)Click here for additional data file."} +{"text": "Acta Cryst. (2014), E70, o133.Erratum to Acta Cryst. (2014), E70, o133], the conformation of the thiazine ring was reported incorrectly.In the paper by Yennawar & Silverberg [ The authors of Yennawar & Silverberg (2014)"} +{"text": "February 7 is National Black HIV/AIDS Awareness Day, an observance intended to raise awareness of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and encourage action to reduce the disproportionate impact of HIV/AIDS on blacks in the United States. Compared with other races and ethnicities, blacks had the highest HIV incidence in 2010, with an estimated rate of 68.9 per 100,000 population, nearly eight times the estimated rate of 8.7 among whites of persons living with HIV, followed by whites (33.0%), and Hispanics (19.3%) (http://www.cdc.gov/features/blackhivaidsawareness. Information regarding blacks and HIV/AIDS is available at http://www.cdc.gov/hiv/risk/racialethnic/aa/index.html.Information regarding National Black HIV/AIDS Awareness Day is available at"} +{"text": "Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment to the Nuclear Envelope. PLoS ONE 10(3): e0118698. doi:10.1371/journal.pone.0118698There is an error in the third author\u2019s name. The correct surname for the third author is: Abi Nahed. The correct given name is: Roland. The correct citation is: Yassine S, Escoffier J, Abi Nahed R, Pierre V, Karaouzene T, Ray PF, et al. (2015) Dynamics of Sun5 Localization during Spermatogenesis in Wild Type and The publisher apologizes for the error."} +{"text": "AbstractLimnatisLimnatisnilotica (LimnatisbacescuiLimnatispaluda (Limnatis leeches are well known species of endoparasitic leeches, Limnatisnilotica was recorded only once in Kazakhstan (nilotica , Limnatispaluda . The firspaluda . The secspaluda . Althougzakhstan .Limnatis from Almaty Province, Kazakhstan are identified as Limnatispaluda. This is the first record of Limnatispaluda from Kazakhstan. Mitochondrial COI and 12S data demonstrated that the present specimens are genetically close to an Israeli specimen identified as Limnatisnilotica. In addition, molecular data suggest that some Limnatis specimens whose DNA sequences have been reported were misidentified. According to the observed phylogenetic relationships, the taxonomic status of the known Limnatis species should be revisited.Specimens of the genus LimnatisLimnatis: L.nilotica and was stated to be a cattle leech there were determined for 2 specimens from Almaty Province. The extraction of genomic DNA and DNA sequencing methods followed Sequences of mitochondrial COI as well as 12S, tRNALimnatis, 10 previously published sequences were obtained from the INSDC for use in molecular phylogenetic analyses Type status:Other material. Occurrence: catalogNumber: Z700; recordedBy: Kanto Nishikawa; individualCount: 1; sex: hermaphrodite; Taxon: scientificName: Limnatispaluda ; Location: country: Kazakhstan; stateProvince: Almaty; verbatimLocality: Suygaty Valley, Almaty Province, Kazakhstan; decimalLatitude: 43.512778; decimalLongitude: 78.9708331; Identification: identifiedBy: Takafumi Nakano; Event: eventDate: 2013-06-21; Record Level: institutionCode: KUZType status:Other material. Occurrence: catalogNumber: Z701; recordedBy: Kanto Nishikawa; individualCount: 1; sex: hermaphrodite; Taxon: scientificName: Limnatispaluda ; Location: country: Kazakhstan; stateProvince: Almaty; verbatimLocality: Suygaty Valley, Almaty Province, Kazakhstan; decimalLatitude: 43.512778; decimalLongitude: 78.9708331; Identification: identifiedBy: Takafumi Nakano; Event: eventDate: 2013-06-21; Record Level: institutionCode: KUZType status:Other material. Occurrence: catalogNumber: Z702; recordedBy: Kanto Nishikawa; individualCount: 1; sex: hermaphrodite; Taxon: scientificName: Limnatispaluda ; Location: country: Kazakhstan; stateProvince: Almaty; verbatimLocality: Suygaty Valley, Almaty Province, Kazakhstan; decimalLatitude: 43.512778; decimalLongitude: 78.9708331; Identification: identifiedBy: Takafumi Nakano; Event: eventDate: 2013-06-21; Record Level: institutionCode: KUZType status:Other material. Occurrence: catalogNumber: Z703; recordedBy: Kanto Nishikawa; individualCount: 1; sex: hermaphrodite; Taxon: scientificName: Limnatispaluda ; Location: country: Kazakhstan; stateProvince: Almaty; verbatimLocality: Suygaty Valley, Almaty Province, Kazakhstan; decimalLatitude: 43.512778; decimalLongitude: 78.9708331; Identification: identifiedBy: Takafumi Nakano; Event: eventDate: 2013-06-21; Record Level: institutionCode: KUZBody firm, muscular, with constant width in caudal direction, dorsoventrally compressed, BL 22.64\u201336.73 mm, BW 4.47\u20139.82 mm Fig. 22.Somite I completely merged with prostomium Fig. a. somite333355555Male gonopore in XI b5/b6 Fig. . Female Eyes 5 pairs, in parabolic arc; 1st and 2nd pairs on II + III, 3rd pair on IV (a1 + a2), 4th pair on V (a1 + a2), and 5th pair on VI a2 . In the neighbour-joining tree based on COI sequences, this monophyletic lineage and one sequence obtained from the Afghan L.paluda formed a well-recovered clade (BS = 100%). In addition, the neighbour-joining trees revealed that sequences obtained from L.nilotica collected in Namibia and Croatia do not form a monophyletic group.Neighbour-joining trees generated based on both the COI Fig. and 12S L.paluda and the Israeli L.nilotica was 0.2% of teeth on each jaw (the latter species has numerous teeth on each jaw). He also mentioned that the numbers of teeth in L.paluda and L.nilotica never overlapped. L.paluda was at most 45, but that of L.nilotica ranged from 45 to 60. However, L.nilotica possessed 30\u201350 teeth on each jaw. Based on the specimens collected in Azerbaijam, Kazakhstan and Uzbekistan, L.nilotica bore 38\u201340 teeth on each jaw. In addition, L.bacescui possessed 50\u201354 teeth on each jaw . In addition, it is highly likely that L.cf.nilotica of Croatia and Bosnia and L.cf.nilotica of Namibia do not belong to the same species, because those specimens are paraphyletic consistently in the present phylogenetic trees, and the former is highly diverged from the latter (11.9% in COI and 3.9% in 12S). These uncorrected p-distance values are greater than those between L.paluda and the Namibian Limnatis species (7.3\u20137.4% in COI and 2.8% in 12S) as well as L.paluda and the Balkan Limnatis specimens (9.2\u20139.7% in COI and 2.8% in 12S).As mentioned above, the taxonomic identities of ioned in , becauseLimnatispaluda analysed in this study have low genetic divergences (0.2\u20130.5% in COI and 0% in 12S). The COI uncorrected p-distances between the present Kazakhstani specimens and the Israeli specimen are lower than that between the former and the Afghan specimen (0.5%) and that between the latter and the Afghan L.paluda (0.6%). The collection locality in Kazakhstan is ca. 4,000 km from Israel, and ca. 2,000 km from Afghanistan. In contrast, Israel is at most ca. 3,500 km from Afghanistan. Because few DNA sequences of L.paluda are available, it may be difficult to reveal its detailed genetic structure. However, the results of the mitochondrial genetic analyses at least shed light on the discordance between the COI genetic divergence between the Kazakhstani L.paluda and the Israeli specimen and the geographic distance between the collection localities. Limnatis species are endoparasitic leeches that attach to the nasopharyngeal cavities of mammals, they likely achieve long-distance dispersal. Except when they parasitise the mammalian nasopharyngeal cavities, Limnatis species generally inhabit a freshwater environment. One of the routes of the Silk Road passed through the Ili River Depression (Limnatispaluda have possibly dispersed by means of freshwater places along the trade route as stepping stones, and thus human activities may have influenced the distribution of L.paluda. In either case, further taxonomic studies of Limnatis species should be performed to clarify their taxonomic positions. In addition, future molecular studies should elucidate the biogeographical history of Limnatispaluda.It is noteworthy that the specimens of pression , near th"} +{"text": "Treatment of juvenile idiopathic arthritis (JIA) has changed dramatically since the introduction of biologics in 1999. Because of more insight in the cytokines involved in JIA the number of available biologic agents increased. Together with the introduction of these new drugs, new insights in the optimal treatment of JIA indicate that earlier and more aggressive therapy is associated with better outcomes. Whether these developments with regard to biologic treatment have resulted in better patients' outcomes in daily practice is not yet reported.To evaluate trends in prescription of biologics and influence on outcomes of Dutch JIA patients that started their first biologic between 1999 and 2010.The Arthritis and Biologicals in Children register aims to include all JIA patients in the Netherlands who use or used biologic agents since 1999. Patients were divided in time periods according to the year of introduction of first biologic agent. Trends in characteristics of patients before introduction of first biologic and effectiveness of the first biologic were analyzed over a 12 year period.343 non-systemic and 86 systemic JIA patients started at least 1 biologic agent between 1999 and 2010. Etanercept remained biologic of first choice for non-systemic JIA and anakinra has become first choice for systemic JIA. The use of systemic prednisone and synthetic disease-modifying anti-rheumatic drugs (besides methotrexate) prior to biologics decreased. During these 12 years of observation, biologics were prescribed after shorter disease durations; the proportion of patients with less than 1.5 years of disease duration before start of the first biologic agent increased from zero in the years 1999-2001 to 31% in 2008-2010. Disease activity and acquired sequelae at baseline decreased with regard to number of joints with arthritis (median of 18 in 1999-2001 decreased to 5 in 2008-2010), number of joints with limited motion (median of 12 in 1999-2001 decreased to 3 in 2008-2010) and functional disability (CHAQ) scores (median score of 1.8 in 1999-2001 decreased to 1.1 in 2008-2010). In systemic JIA biologics are now being introduced in patients with higher ESR values. These changes resulted in more patients with inactive disease and less joints with limited motion after 3 and 15 months of treatment in all JIA categories.Biologics are prescribed increasingly, are introduced earlier during the disease course and in JIA patients with lower disease activity. These changes are accompanied by better short-term disease outcomes. Etanercept remains biologic of first choice for non-systemic JIA and anakinra has become first choice for systemic JIA.M. Otten Grant/Research Support from: Abbott, Novartis, Roche, Pfizer, Consultant for: Roche, J. Anink: None declared., F. Prince: None declared., M. Twilt: None declared., S. Vastert Consultant for: Novartis, R. Ten Cate Grant/Research Support from: Pfizer, Consultant for: Pfizer, E. Hoppenreijs: None declared., W. Armbrust: None declared., S. Gorter: None declared., P. Van Pelt: None declared., S. Kamphuis Grant/Research Support from: Pfizer, glaxosmithkline, K. Dolman: None declared., J. Swart: None declared., J. Van den Berg: None declared., Y. Koopman-Keemink: None declared., M. Van Rossum: None declared., N. Wulffraat Grant/Research Support from: Pfizer, Novartis, Roche, abbvie, L. Van Suijlekom-Smit Grant/Research Support from: Dutch Board of Health Insurances, Dutch Arthritis Association, Pfizer, Abbott, Consultant for: Roche, Novartis."} +{"text": "Nucleic Acids Res. 2014 Feb;42(3):1831-44. doi: 10.1093/nar/gkt1032The authors would like to apologize for an error in the caption of Figure"} +{"text": "Reference 27 is omitted from the last sentence of the second last paragraph of the Methods section. The sentence should read: In addition, as a supplementary analysis, we made these comparisons for estimates from two models reported by Lazer et al., who developed regression models to improve upon GFT estimates .http://dx.doi.org/10.7910/DVN/24823 UNF:5:BJh9WzZQNEeSEpV3EWs+xg== IQSS Dataverse Network [Distributor] V1 [Version].The reference is: Lazer D, Kennedy R, King G, Vespignani A (2014) Replication data for: The parable of Google Flu: Traps in big data analysis. Available: In the \"Estimate\" column of S2 Table(DOCX)Click here for additional data file."} +{"text": "Nature Communications6: Article number: 7870 10.1038/ncomms8870 (2015); Published: 07282015; Updated: 06222016In Fig. 1b of this Article, the sex of patient 2.1 in family A is incorrect, and should be depicted as male. The correct version of this figure appears below.Figure 1"} +{"text": "Correction to:British Journal of Cancer (2016) 114, 88\u201395; doi:10.1038/bjc.2015.314; published online 10 December 2015British Journal of Cancer, one of the authors identified an error in the spelling of their name. Margreet L\u00fcchtenborg appears correctly in the author list above.Upon publication of the above paper in the"} +{"text": "Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: protocol for a collaborative meta-analysis. BMJ Open 2016;6:e010067. This paper has been resupplied with the correct license statement.Hartwig FP, Davies NM, Horta BL,"} +{"text": "International Journal of Environmental Research and Public Health [http://www.mdpi.com/1660-4601/11/11/11879.The authors wish to update the Acknowledgments in their paper published in c Health , doi:10."} +{"text": "In the online version of the article, a space was erroneously omitted from the second author's name. The correct name is Md. Imtaiyaz Hassan. The correct citation is:Shahbaaz M, Hassan MI, Ahmad F (2013) Functional Annotation of Conserved Hypothetical Proteins from Haemophilus influenzae Rd KW20. PLoS ONE 8(12): e84263. doi:10.1371/journal.pone.0084263The name and citation are correct on the PDF."} +{"text": "Nature Communications6: Article number: 10224 10.1038/ncomms10224 (2015); Published: 12212015; Updated: 03092016a contain black numerical labels that are incorrect, and light blue labels that are correct. A revised version of Fig. 5, with correct labels in black throughout, appears below.In Fig. 5 of this article, the three dot plots in the first row of panel Figure 5"} +{"text": "The following information is missing from the Funding section: This work was supported by Taylor's University through its Postgraduate Research Scholarship Programme to MSWP. The complete, correct funding information is as follows: This work was supported by Exploratory Research Grants Scheme ERGS/1/2012/STG08/TAYLOR/03/2) to YYC, and Fundamental Research Grant Scheme (FRGS/2/2010/SKK/TAYLOR/03/1) to YYC. This work was supported by Taylor's University through its Postgraduate Research Scholarship Programme to MSWP. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."} +{"text": "Database 2016 (2016), doi:10.1093/database/baw080The URL present in the abstract of the above article was included by mistake, and this has now been corrected online. The publisher apologizes for this error."} +{"text": "A 9-valent human papillomavirus (HPV) vaccine was licensed for use in females and males in the United States in December 2014 .http://www.cdc.gov/vaccines/who/teens/downloads/9vHPV-guidance.pdf).In February 2015, the Advisory Committee on Immunization Practices (ACIP) recommended 9-valent HPV vaccine as one of three HPV vaccines that can be used for routine vaccination of females and one of two HPV vaccines for routine vaccination of males. ACIP recommendations were published in a March 2015 report . Additio"} +{"text": "Additionally, this study was supported by the Grant Agency of the Czech Republic (Project GPP505/12/P647). Daniel Ricard was supported by project CZ.1.07/2.3.00/30.0032 , co-financed by the European Social Fund and the state budget of the Czech Republic.The following information is missing from the Funding section: This study received institutional support from the Czech Academy of Sciences and the CEKOPOT project (CZ.1.07/2.3.00/20.0204), co-financed by the European Social Fund and the state budget of the Czech Republic. Additionally, this study was supported by the Grant Agency of the Czech Republic (Project GPP505/12/P647). Daniel Ricard was supported by project CZ.1.07/2.3.00/30.0032 , co-financed by the European Social Fund and the state budget of the Czech Republic. Ecohydros S.L. provided support in the form of salaries for authors [AMH], but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the \u2018author contributions\u2019 section.The complete, correct funding statement should read: This study received institutional support from the Czech Academy of Sciences (RVO:60077344,"} +{"text": "The publisher apologizes for the error.There is an error in the author name in the correction published on June 27, 2013. The correct name is Adzemovic MZ. The correct citation is: Adzemovic MZ, Zeitelhofer M, Eriksson U, Olsson T, Nilsson I (2013) Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response. PLoS ONE 8(2): e56586. doi:"} +{"text": "Nature Communications6: Article number: 10005 10.1038/ncomms10005 (2015); Published: 11242015; Updated: 06072016In the original version of this Article the chemical structures of 2-ketoisovaleric acid and isobutanal in Fig. 3a were incorrect. The correct version of Fig. 3 appears below.Figure 3"} +{"text": "The following information was missing from the Funding section: This work was supported in part by the NIH Epi4K Sequencing, Bioinformatics and Biostatistics Core grant number U01NS077303. There was an error in reference 15. The correct reference is: Nature. Advance online publication. doi:10.1038/nature12439 Epi4K Consortium & Epilepsy Phenome/Genome Project (2013). De novo mutations in epileptic encephalopathies."} +{"text": "Correction to:British Journal of Cancer (2016) 114, 723\u2013730; doi:10.1038/bjc.2016.41; published online 22 March 2016Updated online 26 May 2016: This article was originally published under a standard BJC licence, but has now been made available under a CC BY 4.0 licence. The PDF and HTML versions of the paper have been modified accordingly."} +{"text": "Streptococcus, Toronto, Ontario, Canada . The article has been corrected online (http://wwwnc.cdc.gov/eid/article/21/4/14-0759_article).An incorrect version of the Technical Appendix was provided online for the article Population Structure and Antimicrobial Resistance of Invasive Serotype IV Group B"} +{"text": "Nature Communications6: Article number: 6198 10.1038/ncomms7198 (2015); Published: 02052015; Updated: 02012016In Figure 2b of this article, the sets of arrows connecting 'I' and 'M' in the kinetic scheme are inverted. The correct version of Fig. 2 appears below.Figure 2 |"} +{"text": "AbstractMononychellus is represented by 28 herbivorous mites. Some of them are notorious pests of cassava (Manihot esculenta Crantz), a primary food crop in the tropics. With the exception of Mononychellus tanajoa (Bondar), their geographic distribution is not widely known. This article therefore reports observational and specimen-based occurrence data of Mononychellus species associated with cassava. The dataset consists of 1,513 distribution records documented by the International Center for Tropical Agriculture (CIAT) between 1975 and 2012. The specimens are held at CIAT\u2019s Arthropod Reference Collection (CIATARC). Most of the records are from the genus\u2019 native range in South America and were documented between 1980 and 2000. Approximately 61% of the records belong to M. tanajoa, 25% to M. caribbeanae (McGregor), 10% to M. mcgregori (Flechtmann and Baker) and 2% to M. planki (McGregor). The complete dataset is available in Darwin Core Archive format via the Global Biodiversity Information Facility (GBIF).The genus This genus includes several species of herbivorous mites that are major pests of cassava (Manihot esculenta Crantz), most notoriously Mononychellus tanajoa (Bondar). We report 1,513 distribution records of the genus, documented by the International Center for Tropical Agriculture (CIAT) between 1975 and 2012. Most of the records (53%) correspond to specimens preserved at CIAT\u2019s Arthropod Reference Collection (CIATARC). Prior to this contribution, only 30 distribution records of Mononychellus were accessible through the Global Biodiversity Information Facility (GBIF) data portal (accessed 1/13/2014). Accordingly, the CIATARC Mononychellus dataset should facilitate a much better understanding of the genus\u2019 geographic association with cassava.General taxonomic coverage description: Most records were identified to species level (98%) with the help of expert input . Only four species of the genus are reported. Approximately 61% of the records belong to Mononychellus tanajoa, 25% to Mononychellus caribbeanae (McGregor), 10% to Mononychellus mcgregori (Flechtmann and Baker) and 2% to Mononychellus planki (McGregor).PageBreakKingdom:Animalia.Phylum:Arthropoda.Class:Arachnida.Order:Trombidiformes.Family:Tetranychidae.Genus:Mononychellus.Species:Mononychellus caribbeanae, Mononychellus mcgregori, Mononychellus planki, Mononychellus tanajoa.Common name: Cassava Green Mite (for Mononychellus tanajoa), Cassava Green Mite Complex PageBreakGeneral spatial coverage: The Mononychellus specimens and observations of CIATARC are from South America (14 countries) and Central America , which represent the 99% of records, with Colombia and Venezuela are the best represented countries, followed by Brazil and Ecuador .PageBreakSpecimen preservation method: Specimens are preserved as microslide preparations in microscope slide boxes within cabinet drawers maintained at 21.0 \u00b1 0.4 C and 47.6 \u00b1 8.6 relative humidity. They are sorted numerically by species and country of origin.Curatorial unit: 3,510 with an uncertainty of 0 (microslide preparation).Method step description: The dataset integrates two data flows: observational records and specimen-based records, identified either to genus or to species. The former were digitized from field diagnostic forms completed by personnel extensively trained in mite identification. These identifications, however, were likely conducted on site without mounting and preserving samples. Alternatively, these observations may correspond to properly-mounted but lost specimens. In either case, our confidence in the identification of observational records is high to the genus level, but moderate to the species level. On the other hand, specimen-based records belong to verifiable samples properly-preserved at CIATARC following the guidelines of http://www.dane.gov.co/Divipola/ for Colombia, http://www.inec.gob.ec/estadisticas/?option=com_content&view=article&id=80 for Ecuador, etc. [accessed 2013/11/14]). Based on their locality names, we then geocoded the records using Google Maps (https://maps.google.com/), GeoNames (http://www.geonames.org/) or http://www.gbif.org/dataset/785cf038-7b79-4c2f-9e9e-eb940fcd4c0c).All biodiversity data available was digitized in a Microsoft Excel 2010 spreadsheet adopting the Darwin Core Archive format v1.2 . We updaSampling description: The records in the dataset have been documented in three ways:1) Records from CIAT\u2019s initial field explorations to document pests in cassava Records documented during the \u201cCassava Green Spider Mite Biological Control Project,\u201d led by CIAT, International Institute of Tropical Agriculture (IITA), Commonwealth Institute of Biological Control (CIBC) and Empresa Brasileira de Pesquisa Agropecu\u00e1ria (EMBRAPA) (n Africa .3) Records from other sources; including field inspections and collections conducted during routine farm visits by CIAT personnel, and from specimens submitted to CIATARC by fellow institutions and researchers .Object name: Darwin Core Archive Mononychellus distribution: data of the CIAT Arthropod Reference Collection of International Center for Tropical Agriculture (CIAT).Character encoding: UTF-8.Format name: Darwin Core Archive format.Format version: 1.0.Distribution:http://www.gbif.org/dataset/785cf038-7b79-4c2f-9e9e-eb940fcd4c0cPublication date of data: 2014-03-14.Language: English.Licenses of use: This dataset [Mononychellus Collection of CIAT Arthropod Reference Collection (CIATARC)] is made available under the Creative Commons Zero (CC0) 1.0.PageBreak"} +{"text": "Nature Communications6:8136 doi: 10.1038/ncomms9136 (2015); Published 09182015; Updated 06152016The original version of this Article failed to fully credit the use of the Ocean Data View software in figure 1 and supplementary figure 12, which appears below:http://odv.awi.de, 2016.Schlitzer, R., Ocean Data View,"} +{"text": "In Vivo and Assessment of the Specificities of the Anti-Bovine CD1 Antibodies. PLoS ONE 10(3): e0121923. doi:10.1371/journal.pone.0121923This article was republished on May 13, 2015, to correct the third and seventh authors\u2019 names. The third author\u2019s given name is Chema and surname is El Messlaki. The seventh author\u2019s given name is Ildiko and surname is Van Rhijn. The correct citation is: Nguyen TKA, Reinink P, El Messlaki C, Im JS, Ercan A, Porcelli SA, et al. (2015) Expression Patterns of Bovine CD1 The publisher apologizes for the errors. Please download this article again to view the correct version. The originally published, uncorrected article and the republished, corrected article are provided here for reference.S1 File(PDF)Click here for additional data file.S2 File(PDF)Click here for additional data file."} +{"text": "There is an error in reference 24. The correct reference is: Obirikorang C, Selleh PK, Abledu JK and Fofie CO (2013) Predictors of Adherence to Antiretroviral Therapy among HIV/AIDS Patients in the Upper West Region of Ghana. ISRN AIDS 2013: 873939.In"} +{"text": "Two grant numbers are inadvertently omitted in the Funding section. The correct funding information is as follows:http://www.dfg.de/en/) (DFG BO3790/1-1), DFG (FI1781/1-1) and the following grants from the ESRC (http://www.esrc.ac.uk/) (ES/L010690/1) and (ES/M009203/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Authors are funded by the following grants from the DFG (The publisher apologizes for this error."} +{"text": "There is an error in the first author\u2019s name in the article published on September 13, 2013 and in the correction published on December 17, 2015. The correct name is: Uzma Bashir.10.1371/journal.pone.0074018.The correct citation for the article is: Bashir U, Alam MM, Sadia H, Zaidi SSZ, Kazi BM (2013) Molecular Characterization of Circulating Respiratory Syncytial Virus (RSV) Genotypes in Gilgit Baltistan Province of Pakistan during 2011\u20132012 Winter Season. PLoS ONE 8(9): e74018. doi:10.1371/journal.pone.0145599. The publisher apologizes for the error.The correct citation for the correction is: Bashir U, Alam MM, Sadia H, Zaidi SSZ, Kazi BM (2015) Correction: Molecular Characterization of Circulating Respiratory Syncytial Virus (RSV) Genotypes in Gilgit Baltistan Province of Pakistan during 2011\u20132012 Winter Season. PLoS ONE 10(12): e0145599. doi:"} +{"text": "Haemophilus ducreyi Infections . The online edition of the article is correct, and the online PDF has been corrected (http://wwwnc.cdc.gov/EID/article/22/1/14-0425_article).Some references were cited incorrectly in the print and initial PDF editions of Epidemiology of"} +{"text": "There is an error in the title of this paper: \u201cCombing\u201d should be \u201cCombining.\u201d The correct title is: Ecological Change, Sliding Baselines and the Importance of Historical Data: Lessons from Combining Observational and Quantitative Data on a Temperate Reef Over 70 Years.10.1371/journal.pone.0118581The correct citation is: Gatti G, Bianchi CN, Parravicini V, Rovere A, Peirano A, Montefalcone M, et al. (2015) Ecological Change, Sliding Baselines and the Importance of Historical Data: Lessons from Combining Observational and Quantitative Data on a Temperate Reef Over 70 Years. PLoS ONE 10(2): e0118581. doi:"} +{"text": "In the Funding section, the grant number from the funder National Science Centre is listed incorrectly. The correct grant number is: 2011/03/D/HS6/05951."} +{"text": "Nature Communications6:6961 doi: 10.1038/ncomms7961 (2015); Published 04242015; Updated 2016The original version of this Article failed to fully credit the use of the Ocean Data View software in figure 3, which appears below:http://odv.awi.de, 2016.Schlitzer, R., Ocean Data View,"} +{"text": "The publisher apologizes for the errors.The first and third authors\u2019 names appear incorrectly in the citation. The correct names are: Kanthack TFD and Altimari LR. The correct citation is: Kanthack TFD, Guillot A, Altimari LR, Nunez Nagy S, Collet C, Di Rienzo F (2016) Selective Efficacy of Static and Dynamic Imagery in Different States of Physical Fatigue. PLoS ONE 11(3): e0149654. doi:"} +{"text": "Western Journal of Emergency Medicine :786\u2013787. DOI: 10.5811/westjem.2015.6.27582), there were the following errors in the published article:In the Original Research article entitled \u201cHydrocele of the Canal of Nuck,\u201d published in the October 2015 issue of the 1. On page 786, the following authors should have been included: Phillip Aguiniga, Jason Blake. They are research assistants at the Department of Emergency Medicine, Kern Medical Center, Bakersfield, California.We apologize for this error."} +{"text": "There are errors in the Funding section. The correct funding information is as follows:http://abc.uva.nl/research/nav), the European Union 7th Framework Programme (FP7/2007-2013) under grant agreement no. 604102 , and the Deutsche Forschungsgemeinschaft (DFG), SFB 936/Z1 (http://www.sfb936.net). These funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.This work was funded by the Amsterdam Brain and Cognition priority program; grant number: ABC2014-01 ("} +{"text": "A reader has brought to our attention that there are errors in references 27, 28, and 29.The correct reference for 27 is: Froeschle JE, Feorino PM, Gelfand HM. A continuing surveillance of enterovirus infection in healthy children in six United States cities. II. Surveillance enterovirus isolates 1960\u20131963 and comparison with enterovirus isolates from cases of acute central nervous system disease. American journal of epidemiology. 1966;83:455\u201346910.1002/rmv.326The correct reference for 28 is the same as for reference 31: Kim KS, Hufnagel G, Chapman NM, Tracy S (2001) The group B coxsackieviruses and myocarditis. Rev Med Virol 11: 355\u2013368. doi: The correct reference for 29 is: Modlin JF, Rotbart HA. Group B coxsackie disease in children. Current topics in microbiology and immunology. 1997;223:53\u201380The authors confirm that all other references are listed correctly."} +{"text": "Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cellsWENTING QI, YAN GAO, JUN TIAN and HONGWEI JIANGInt J Mol Med 34: 1483\u20131491, 2014; DOI: 10.3892/ijmm.2014.1941All the authors agree to the withdrawal of this manuscript. The retraction has been agreed to as the authors have admitted that the manuscript contains a substantial amount of material from the following study: Hassanpour S, Jiang H, Wang Y, Kuiper JW and Glogauer M: The actin binding protein adseverin regulates osteoclastogenesis. PLoS One 9: e109078, 2014. Thus, this cannot be considered as original work."} +{"text": "CORRECTIONRambam Maimonides Med J 2010;1(2):e0011. doi:10.5041/RMMJ.10011Youdim MBH. Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson\u2019s and Alzheimer\u2019s disorders? , it was noted that the Acknowledgement regarding the source of the text was not published. The following Acknowledgement has been added:In the following paper: Acknowledgement: This article is reprinted with slight modifications from Youdim MBH. Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson\u2019s and Alzheimer\u2019s Diseases as Disease Modifying Agents. Exp Neurobiol. 2010;19(1):1\u201314, under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/).The HTML and PDF versions of the paper have been corrected in the RMMJ.org.il archives.Published: August 31, 2015"} +{"text": "Cebus\u201d). The correct citation is: Makedonska J, Wright BW, Strait DS (2012) The Effect of Dietary Adaptation on Cranial Morphological Integration in Capuchins . PLoS ONE 7(10): e40398. doi:10.1371/journal.pone.0040398The word \u201cAdaptation\u201d is misspelled in the article title. The correct title is: The Effect of Dietary Adaptation on Cranial Morphological Integration in Capuchins (Order Primates, Genus \u201c"} +{"text": "AbstractLasiusalienoflavus Bingham, 1903. This species has hitherto been reported only from the Himalayas, and the present data are also based on specimens collected in the north-western part of the mountain range. Likewise other Himalayan ants, this species also shows restricted distribution, which suggests a rather high degree of endemism (45%) of this group in the Himalayas.The present paper provides a description of the male caste and re-description of the worker and queen castes of the poorly known ant species Lasius Fabricius, 1804 is hithrto known to comprise 111 extant species and 3 subspecies , Lasiusnearcticus Wheeler, 1906 Lasiusalienoflavus Bingham, 1903, Lasiustalpa Wilson, 1955 and Lasiusfallax Wilson, 1955 forming the flavus-group in a distinct subgenus Cautolasius Wilson, 1955, and provided a key to the Palaearctic species. Lasiussensu stricto from the Palaearctic, describing 17 new species, and updated Wilson's key to the Palaearctic species. Other significant contributions form the Palaearctic region include: Lasius (Dendrolasius) species of East Palaearctic.The genus bspecies . In the bspecies . A revisLasiusalienoflavus Bingham, 1903 from the Himalayas (above 8000 feet) with reports of worker and queen castes. Later on purely morphological grounds Cautolasius and placed Lasiusalienoflavus in it. This subgenus comprises a group of species showing a mixture of characters that put them in a position intermediate between Lasiussensu stricto and Chthonolasius. Subsequently, Lasiusalienoflavus and provided a key to the Himalayan members of the genus. In the discussion part he mistakenly assigned the species to the subgenus Chthonolasius. Recently Lasius from the Himalayas.Lasiusalienoflavus based on fresh material and for the first time provide a description of the male caste.Here we re-describe the worker and queen castes of The specimens were collected by handpicking. The morphological analysis was carried on with the aid of a Nikon SMZ 1500 stereo zoom microscope. All digital images were taken with a MP evolution digital camera and subsequently processed with Auto-Montage software and Adobe Photoshop CS5. All measurements were recorded in millimeters using oculometer between 50\u00d7 and 125\u00d7 to the nearest 0.001 mm and have been rounded to the nearest 0.01 mm (as the average recording error was approximately 0.005 mm). Specimens have been deposited in PUPAC, Punjabi University Patiala Ant Collection, Patiala. \u2013 Length of the head measured in full face view in a straight line from the middle of the anterior clypeal margin to the middle of the occipital margin. The head has to be carefully tilted to the position with the real maximumHL. \u2013 Maximum width of the head in full face view, behind the eyesHW. \u2013 Maximum eye length with eye in full face viewEL. \u2013 Diameter of eye measured perpendicularly to transect in EL and across structurally defined ommatidiaEW. \u2013 Maximum straight-line length of the scape excluding the basal neck and the condyleSL. \u2013 Weber\u2019s length \u2013 the length of mesosoma in profile from the margin of neck shield to the posterior margin of propodeal lobesWL. \u2013 Maximum width of the petiole from above, in dorsal viewPW. \u2013 The length of the gaster in lateral view from the anterior most point of first gastral segment to the posterior most point (excluding sting if present)GL. \u2013 Head size \u2013 the total of head length and head width divided by hundredHS. \u2013 Number of standing hairs projecting > 0.02 mm from dorsal profile of scape i.e. the number of hairs visible when looking at the small diameter of scape under transmitted-light conditions. The always present hairs on distal apex are not counted and the number refers to one scapenHS. \u2013 Number of standing hairs projecting > 0.02 mm from extensor profile of one hind tibia. The always present hairs on distal apex are not counted and the number refers to one tibianHHT. \u2013 The total outstretched length in profile from anterior clypeal margin to the posterior most point of gaster excluding stingTL. \u2013 CI = HL/HW \u00d7 100Cephalic Index \u2013 EI = EL/HW \u00d7 100Eye Index1 = SL/HL \u00d7 100 \u2013 SIScape Index2 = SL/HW \u00d7 100 \u2013 SIScape IndexBingham, 1903Lasiusalienoflavus Bingham, 1903 \u2013 Lasius (Cautolasius) alienoflavus \u2013 Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 23 workers; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Himachal Pradesh: Khajjiar; maximumElevationInMeters: 2100; Event: eventDate: 2010-07-01; Record Level: collectionCode: Insect (Ants)Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 63 workers; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Himachal Pradesh: Kharapathar; maximumElevationInMeters: 2800; Event: eventDate: 2008-08-13; Record Level: collectionCode: Insect (Ants)Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 20 workers, 2 queens, 1 male; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Himachal Pradesh: Manali; maximumElevationInMeters: 1800; Event: eventDate: 2010-06-17; Record Level: collectionCode: Insect (Ants)Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 3 workers; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Himachal Pradesh: Sungri; maximumElevationInMeters: 2600; Event: eventDate: 2008-08-14; Record Level: collectionCode: Insect (Ants)Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 62 worker; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Jammu & Kashmir: Sarthal; maximumElevationInMeters: 3000; Event: eventDate: 2010-06-04; Record Level: collectionCode: Insect (Ants)Type status:Other material. Occurrence: recordedBy: Irfan Gul; sex: 105 workers, 3 queens; Location: country: India; stateProvince: North-West Himalaya; verbatimLocality: Uttarakhand: Gangotri; maximumElevationInMeters: 3000; Event: eventDate: 2010-06-04; Record Level: collectionCode: Insect (Ants)Fig. 1Measurements: HL 0.82\u20130.91; HW 0.75\u20130.86; EL 0.12\u20130.15; EW 0.09\u20130.12; SL 0.70\u20130.80; WL 0.88\u20131.04; PW 0.20\u20130.24; GL 0.61\u20131.05; HS 0.78\u20130.88; CI 101\u2013109; EI 15\u201318; SI1 80\u201388; SI2 85\u201395; nHS+nHHT < 8; TL 2.5\u20132.8. n = 32.Head: Head roughly rectangular in full face view (CI = 101\u2013109); posterior margin of head straight; posterolateral corners rounded; a few setae present closer to posterior margin of head but not reaching the hind margin of eyes and less denser than in Lasiuselevatus Bharti et Gul, 2013; lateral sides of head more-or-less parallel, somewhat narrowing anteriorly; anterior clypeal margin broadly convex, clypeal carina absent; lateral clypeal profile convex; eyes almost round, size larger as compared to other species of the same group (EI = 15\u201318); mandibles triangular, the masticatory margin with 7 to 8 teeth, rarely 9, including denticles; antennae 12 segmented, scape long, distinctly surpassing the posterior margin of head .Mesosoma and petiole: Mesosoma with weakly convex promesonotal dorsum slightly depressed at the suture; propodeal dome rather hemispheric, as high as mesonotum, posterior slope of propodeum somewhat straight; area between propodeal spiracle and metapleural gland without distinct setae; in frontal view petiole with weakly convex sides and rather straight dorsum, in profile with steep and slightly convex anterior face and straight posterior face; gaster more-or-less ovate.Sculpture and pilosity: Head and mesosoma with shallow micropunctures; in general body smooth and fairly shiny with scattered pilosity; body covered with suberect to erect setae, abundant and longest on gaster; cuticular surface covered with smooth and rather dense pubescence; genae without standing hairs or setae; scape with subdecumbent to decumbent pubescence, a few setae present at the proximal end; hind tibia pubescence smooth, setae are normally present at the proximal end.Colour: The species is light to dark yellow in colour; the masticatory margin dark brownish and the eyes black in colour; pubescence pale-yellow.Fig. 2Measurements: HL 1.12\u20131.15; HW 1.32\u20131.37; EL 0.34\u20130.36; EW 0.26\u20130.27; SL 1.0\u20131.02; WL 2.33\u20132.45; PW 0.24\u20130.26; GL 2.30\u20132.70; HS 1.24\u20131.26; CI 81\u201384; EI 25\u201326; SI1 87\u201389; SI2 73\u201374; TL 5.7\u20136.3. n = 2.Resembles the worker, with modifications expected for caste and the following differences: body massive, hairy; lateral sides of head subparallel, narrowing towards the anterior margin; eyes much larger; mesosoma enlarged, dorsally flat, scutum and scutellum at the same level, propodeal declivity very steep; in profile view petiole compressed, in frontal view dorsum emarginate; gaster long and gibbous; setae scattered all over and short; head, mesosoma and gaster dark brown, legs dark yellow in colour.Fig. 3Measurements: HL 0.6; HW 0.7; EL 0.27; EW 0.18; SL 0.48; WL 1.3; PW 0.25; GL 1.7; HS 0.65; CI 86; EI 38; SI1 80; SI2 68; TL 3.6. n = 1.Head: Head roughly squarein full face view (CI = 86); Head broader at the posterior margin, narrowingtowards the anterior margin; posterior margin of head slightly convex; posterolateral corners rounded; Hairsdenser towards the posterior margin of head; lateral sides of head distinctly narrowinganteriorily; eyes very large, bulging beyond head outline in full-frontal view (EI = 38); three prominent ocelli present at the centre; antennae 13 segmented, filiform; scape long, distinctly surpassing the posterior margin of head ; clypeus smooth, without any carina in the middle; anterior clypeal margin broadly convex; lateral clypeal profile convex; mandiblewith an apical tooth and 3 denticles at the centre of masticatory margin.Mesosoma and petiole: Mesosomaenlarged to accommodate flight muscles; pronotum small; scutum smooth; scutellum somewhat raised; declivity steep; in frontal view petiole dorsallyround; gaster lengthened, tapering towards the apex.Sculptureand pilosity: Ingeneral body smooth with scattered pilosity; body covered with suberect toerect setae, abundant and longest on gaster; cuticular surface covered withsmooth and rather dense pubescence abundant towards the apex of gaster, antennaeand legs; Hairs more dense on the posterior margin of head, sparselydistributed over rest of the head; standinghairs or setae on genae sparse; mandibles with a few setae at the apicalportion; a few setae present on the anterior margin of clypeus; small blunthairs thinly present on the eyes; scape with subdecumbent to decumbentpubescence, a few setae present at the proximal end; hind tibia pubescencesmooth, setae are normally present at the proximal end.Genitals: Paramereselongated, roughly triangular, covered with long setae; cuspi with short peg-like teeth and bent towards digiti; digiti straight and long, about 3 timesas long as cuspi with round dorsum; penis valve projecting.Colour: brown with a blackish tinge; eyes black; legs and wings creamy-yellowish; body smooth and somewhat shiny all over.The overall distribution of the species is from the Himalaya but the specimens used for this study have been collected from the North-west range of Himalaya. All the collection areas were forested mountains surrounded by other mountains. The nests were very close to the surface with a depth of 3\u20135 inches. The soil surrounding the nest was mainly moist and covered by herbs. 23 specimens were collected from Winkler extraction.Lasiusalienoflavus Bingham, 1903 is well marked off from other reports of this genus and is a distinct species. However, it resembles Lasiusflavus (Fabricius) but can be readily distinguished from it by having the apical segment of the maxillary palp longer than the preapical one ."} +{"text": "A reference is omitted from the fifth sentence of the last paragraph in the Discussion section.The sentence should read: Our data are entirely consistent with and complementary to a parallel study conducted independently in the Rothstein, Klein, Kreicji, and Lisby laboratories .The reference is: Burgess RC, Sebesta M, Sisakova A, Marini VP, Lisby M, et al. (2013) The PCNA Interaction Protein Box Sequence in Rad54 Is an Integral Part of Its ATPase Domain and Is Required for Efficient DNA Repair and Recombination. PLoS ONE 8(12): e82630. doi:10.1371/journal.pone.0082630"} +{"text": "Nature Communications6: Article number:798310.1038/ncomms8983 (2015); Published: 08062015; Updated: 02172016.In Fig. 3d in this Article, the graph depicting flow cytometry of the anaerobic culture was inadvertently duplicated from that depicting the KCN-treated culture during the production process. The correct version of Fig. 3 appears below.Figure 3"} +{"text": "Correction to:Cell Discovery (2016) 2, 16012; doi:10.1038/celldisc.2016.12; published online 17 May 2016During web production, there was an error in Supplementary information: Supplementary Material was omitted. The files are now installed in the online version of the paper. We apologize for any inconvenience that may have been caused by this error."} +{"text": "The percentage of young adults aged 18\u201324 years who had never smoked cigarettes increased by more than 10 percentage points from 1999\u20132001 (65%) to 2011\u20132012 (76%). The increase was noted for men and for women. For each period, women were more likely than men to have never smoked cigarettes.Sources: Schoenborn CA, Adams PF, Barnes PM, Vickerie JL, Schiller JS. Health Behaviors of Adults: United States, 1999\u20132001. Vital Health Stat 2004;10(219).Adams PF, Schoenborn CA. Health behaviors of adults: United States, 2002\u20132004. Vital Health Stat 2006;10(230).Schoenborn CA, Adams PF. Health behaviors of adults: United States, 2005\u20132007. Vital Health Stat 2010;10(245).Schoenborn CA, Adams PF, Peregoy JA. Health behavior of adults: United States, 2008\u20132010. Vital Health Stat 2013;10(257).http://www.cdc.gov/nchs/nhis/quest_data_related_1997_forward.htm.National Health Interview Survey. Data and documentation for 2011 and 2012. Available at"} +{"text": "Petunia: the importance of stress severityPhysiological and molecular responses to drought in Jongyun Kim, Anish Malladi, and Marc W. van IerselJournal of Experimental Botany (2012) 63 (18): 6335\u20136345. doi: 10.1093/jxb/ers28556, 46\u201351).In the above paper, Figure 1 and a subset of the data in Figure 2 were previously published in a proceedings paper of the Southern Nursery Association Research Conference (Kim J, Malladi A, van Iersel MW. 2011. Physiological responses of petunia to different levels of drought stress. Proceedings of Southern Nursery Association Research Conference"} +{"text": "There is an error in the title. The word Fishes has an incorrectly capitalized I. The correct title should be \u201cDNA Barcodes for the Fishes of the Narmada, One of India's Longest River.\u201dThe correct Citation should read: Khedkar GD, Jamdade R, Naik S, David L, Haymer D (2014) DNA Barcodes for the Fishes of the Narmada, One of India\u2019s Longest Rivers. PLoS ONE 9(7): e101460. doi:10.1371/journal.pone.0101460Additionally, there are errors in"} +{"text": "The third author\u2019s name is spelled incorrectly in the correction published on August 11, 2014. The correct name is: K. Suzanne Scherf. The correct citation is: Halliday DWR, MacDonald SWS, Scherf KS, Tanaka JW (2014) A Reciprocal Model of Face Recognition and Autistic Traits: Evidence from an Individual Differences Perspective. PLoS ONE 9(5): e94013. doi:10.1371/journal.pone.0094013. The publisher apologizes for the error."} +{"text": "There is an error in reference 25. The correct reference is: Andres B, Ji Q (2008) A new pterosaur from the Liaoning province of China, the phylogeny of the Pterodactyloidea, and convergence in their cervical vertebrae. Palaeontology 51: 453\u2013469."} +{"text": "The correct citation is: Fortini LB, Vorsino AE, Amidon FA, Paxton EH, Jacobi JD (2015) Large-Scale Range Collapse of Hawaiian Forest Birds under Climate Change and the Need for 21st Century Conservation Options. PLoS ONE 10(10): e0140389. 10.1371/journal.pone.0140389. The publisher apologizes for the error.The publisher erroneously omitted the word \u201cfor\u201d from the article title. The correct title is: Large-Scale Range Collapse of Hawaiian Forest Birds under Climate Change and the Need for 21"} +{"text": "Correction to:British Journal of Cancer (2015) 114, 146\u2013150; doi:10.1038/bjc.2015.421; published online 15 December 2015British Journal of Cancer, one of the authors identified an error in the spelling of their name. V Sivasubramaniam appears correctly in the author list above.Upon publication of the above paper in the"} +{"text": "The third author\u2019s name is abbreviated incorrectly in the citation. The correct citation is: Nemeth M, Millesi E, Wagner KH, Wallner B (2014) Effects of Diets High in Unsaturated Fatty Acids on Socially Induced Stress Responses in Guinea Pigs. PLoS ONE 9(12): e116292. doi:10.1371/journal.pone.0116292There is an error in affiliation 2 for Karl-Heinz Wagner. Affiliation 2 should be: Department of Nutritional Sciences, University of Vienna, Vienna, Austria"} +{"text": "Reason for Erratum:Due to a production error the article was erroneously published in Frontiers in Neuroengineering, instead of Frontiers in Neuroscience. This mistake does not change the scientific conclusions of the article in any way and the publisher apologizes for the error.Old citation:In vivo comparison of the charge densities required to evoke motor responses using novel annular penetrating microelectrodes by Brunton EK, Winther-Jensen B, Wang C, Yan EB, Hagh Gooie S, Lowery AJ, and Rajan R (2015). Front. Neuroeng. 8:5. doi: 10.3389/fneng.2015.00005The original article has been updated."} +{"text": "Consolidation processes, involving synaptic and systems level changes, are suggested to stabilize memories once they are formed. At the synaptic level, dendritic structural changes are associated with long-term memory storage. At the systems level, memory storage dynamics between the hippocampus and anterior cingulate cortex (ACC) may be influenced by the number of sequentially encoded memories. The present experiment utilized Golgi-Cox staining and neuron reconstruction to examine recent and remote structural changes in the hippocampus and ACC following training on three different behavioral procedures. Rats were trained on one hippocampal-dependent task only (a water maze task), two hippocampal-dependent tasks , or one hippocampal-dependent and one non-hippocampal-dependent task (a water maze task followed by an operant conditioning task). Rats were euthanized recently or remotely. Brains underwent Golgi-Cox processing and neurons were reconstructed using Neurolucida software . Rats trained on two hippocampal-dependent tasks displayed increased dendritic complexity compared to control rats, in neurons examined in both the ACC and hippocampus at recent and remote time points. Importantly, this behavioral group showed consistent, significant structural differences in the ACC compared to the control group at the recent time point. These findings suggest that taxing the demand placed upon the hippocampus, by training rats on two hippocampal-dependent tasks, engages synaptic and systems consolidation processes in the ACC at an accelerated rate for recent and remote storage of spatial memories. Consolidation is distinguished into two specific components, synaptic, and systems consolidation. Synaptic consolidation occurs shortly after acquisition and refers to changes at the cellular level McGaugh, . SystemsSynaptic consolidation processes involve the induction of signaling cascades and second messenger systems, protein synthesis and gene expression alterations, all of which may be important synaptic pathways in the initiation of long-term memory storage processes Kandel, . Once thThe hippocampus critically contributes to the initial encoding and storage of memory representations , two different hippocampal-dependent tasks or one hippocampal-dependent and one non-hippocampal-dependent task . Because impaired hippocampal function does not alter OP task performance . Rats received no nesting material and no direct enrichment of any kind in their home cage. Food was restricted until rats reached 90% of their free-feeding baseline, which was maintained throughout the experiment. Prior to behavioral training, rats were given 5 chocolate pellets (45 mg) in their home cage and handled for 5 min daily. Principles of laboratory animal care were followed and all procedures were conducted in accordance with the Canadian Council on Animal Care and protocols approved by the Carleton University Animal Care Committee.Forty-eight Long Evans rats (190\u2013250 g) from Charles River, Quebec were used. Rats were housed individually in clear plastic cages (26 \u00d7 20 \u00d7 45 cm) and given The WM was located in a room within the animal housing area. The opaque, white, polypropylene pool measured 155 cm in diameter and 60 cm in height. The pool was filled to a depth of 37.5 cm with water that remained at approximately 21\u00b0C. The \u201cescape\u201d platform was made from clear Plexiglas and submerged approximately 2 cm below the surface of the water. Visual cues such as posters and geometric shapes were located on the walls around the room. The experimenter remained in the same position throughout all trials.RAM testing was done in a room within the animal housing area, located across the hall from the WM testing room. The maze was positioned 98.5 cm off the floor. Each arm measured 59 cm long and 11 cm wide. The distance between the ends of arms, where food reward was located, was 32.5 cm. Plastic inserts were placed on the sides of the maze arms to prevent animals from jumping across arms. Visual cues such as posters and geometric shapes were located on the walls around the room. The experimenter remained in the same position throughout all trials.Rats were tested in groups of six using six operant chambers . Each chamber was housed in an insulated box to minimize external noise. Each chamber possessed a pellet dispensing system, two levers separated by a food hopper, a houselight, a grid floor and a three light-panel. OP training took place in a room outside of the animal housing area.n = 24) or remotely . Eight experimental groups resulted (n = 6 in each group): (1) Control:Recent (2) WM:Recent (3) WM/RAM:Recent (4) WM/OP:Recent (5) Control:Remote (6) WM:Remote (7) WM/RAM:Remote (8) WM/OP:Remote.An overview of the behavioral procedure is shown in Figure Rats received 5 training trials per day for 5 days, with a different starting location for every trial within a day and randomized starting locations across days. The hidden platform was located in a fixed location within and across days. Rats were placed in the pool, facing the perimeter, and given a maximum of 60 s to locate the hidden platform. Rats that did not find the hidden platform within 60 s were guided to the platform by the experimenter. All rats remained on the platform for 15 s. Rats then received a 15 s rest period in a holding cage before the next trial. All movement within the pool was tracked using HVS Image 2100 Tracking System . Following the final trial of each day, rats were dried with a towel and placed in a holding cage on a heating pad in the housing room for 10\u201315 min after which they were returned to the home cage.Rats received one day of pretraining and 4 days of testing on the RAM. On the first trial of pretraining, chocolate pellets were located in the starting area, at the entrance to arms, within the arms as well as in the food holes located at the end of each arm. On trial 2 of pretraining, pellets were located within the arms and in food holes only. Trials 3\u20135 of pretraining had pellets located only in food holes.Days 2\u20135 were testing days, where pellets were located in food holes at the ends of 3 of the 5 arms. Baited arms were always the same for an individual rat but differed between rats. Each rat was given 5 trials per day. Trials were a maximum of 5 min each or ended when all food reward had been collected. Rats were placed in a holding cage for 30 s between trials while arms were re-baited. Performance on the maze was manually scored. Sessions were timed, and correct and incorrect arm entries were recorded. An arm entry was defined as all four feet inside an arm.Rats in the WM/OP condition were trained to lever-press for chocolate pellets over 5 days, 30 min per day. Upon pressing the lever to the left of the hopper two times (FR2), the house light extinguished, the panel lights above the lever changed from red to green and the pellet dispenser released one 45-mg chocolate pellet into the hopper. Presses on the right lever had no programmed consequences. Presses on the left lever were considered correct and presses on the right lever, incorrect. The number of lever presses, the number of times a rat poked its nose into the hopper and locomotor activity were recorded automatically .The Golgi method, originally named the \u201cBlack Reaction\u201d was developed by Camillo Golgi in 1873. The invention of the Golgi method marked a huge advancement in the field of neuroscience, largely thanks to Santiago Ramon y Cajal's use of the method. Curiously, and fortunately, the Golgi method stains only a small percentage of cells . Next, brains underwent incubation in 10% (8 h), 20% (8 h), and 30% sucrose (minimum 4 days). 200 \u03bcm thick sections were sliced on a vibratome and mounted onto gelatinized slides. Slides were placed in a humidified, dark box for 24 h before staining.Rats were placed into a Decapicone (Braintree) and decapitated. Brains were rapidly removed and hemisected . One hemisphere was placed in Golgi-Cox fixative and stored at room temperature, away from light, for 14 days. Following incubation in Golgi-Cox fixative, brains underwent 3 washes in DH2O (1 min), 28% Ammonium Hydroxide (40 min), DH2O (1 min), Kodak film fix A (40 min), DH2O (2 \u00d7 1 min), 50, 70, and 95% ETOH (1 min each), desiccated 100% ETOH (3 \u00d7 5 min), desiccated ETOH/Clearene/Chloroform solution (10 min), and desiccated Clearene (2 \u00d7 15 min). Slides were coverslipped with generous amounts of Permount mounting medium (Sigma) and placed in a desiccated box to dry for a minimum of 4 days.Slides were immersed in the following solutions: DHThree pyramidal neurons per rat were analyzed from each brain region. Four rats from each behavioral group were examined. All neuron reconstruction was performed by one experimenter who was unaware of the experimental condition. Brain regions were defined according to Paxinos and Watson . The ACCNeurons to be traced were selected at random, but had to meet predetermined criteria for analysis. Neurons had to be entirely impregnated, staining had to be uniform and complete within processes, the neuron had to be relatively isolated from surrounding impregnated cells or obstructions, and the cell body had to be centrally located within the 200 \u03bcm section depth . Separate analyses were carried out in the ACC and CA1 of the hippocampus and apical and basal dendrites were analyzed separately. Two-Way ANOVAs in each region for apical and basal dendrites were run with Behavioral group and Time (Recent or Remote) as the fixed factors and the characteristic of interest as the dependent variables.Four rats from each behavioral group were examined; three neurons per rat per brain area (ACC and CA1) were analyzed. Thus, resulting in 12 neurons per behavioral condition per brain region . For statistical analysis, the measurements of the three analyzed neurons per rat per brain region were pooled to get one value for each rat = 112.88, p < 0.001] but no main effect of behavior or time.Figure F = 2.82, p = 0.05] but no main effect of time.Two groups received training on the WM followed by training on the RAM: one assigned to receive a recent WM probe test and one assigned to receive a remote WM probe Figure . The numF = 12.73, p < 0.001] but no main effect of time.Two groups received training on the WM followed by training on the operant task: one assigned to receive a recent WM probe test and one assigned to receive a remote WM probe Figure . The numCell body size in the ACC was analyzed using a Two-Way ANOVA with Behavior and time (recent or remote) as the independent variables and cell body size as the dependent variable. No main effect of behavior or time was found (data not shown).Cell body size in the CA1 of the hippocampus was analyzed using a Two-Way ANOVA with Behavior and time (recent or remote) as the independent variables and cell body size as the dependent variable. No main effect of behavior or time was found (data not shown).Figure Number of branches. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of branches as the dependent variable revealed a main effect of behavior with group WM/RAM displaying the greatest number of branches (16). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of branches compared to groups WM/OP:Remote, Control:Recent, and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater number of branches compared to groups WM Only:Recent, WM/OP:Recent, WM/OP:Remote, Control:Recent, and Control:Remote (p < 0.05). Group WM Only:Remote had significantly greater number of branches compared to group Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of branches as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest number of branches (18). Fisher's LSD post-hoc analyses revealed group WM/RAM:Remote had significantly greater number of branches compared to groups from WM Only:Recent, WM Only:Remote, WM/OP:Remote, Control:Recent, and Control:Remote, (p = 0.05). Group WM/OP:Recent had significantly greater number of branches compared to group Control:Recent (p < 0.05).Dendritic Length. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and dendritic length as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest dendritic length (1016 \u03bcm). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater dendritic length compared to groups WM/OP:Remote, Control:Recent, and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater dendritic length compared to groups WM/OP:Remote, Control:Recent, Control:Remote (p < 0.05). Group WM/OP:Recent had significantly greater dendritic length compared to group Control:Remote (p = 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and dendritic length as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest dendritic length (839 \u03bcm). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater dendritic length compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Remote, Control:Recent, and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater dendritic length compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Remote, Control:Recent and Control:Remote (p < 0.05).Number of spines. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of spines as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest number of spines (511). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of spines compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, WM/OP:Remote, Control:Recent and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater number of spines compared to groups Control:Recent and Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of spines as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest number of spines (385). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of spines compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, WM/OP:Remote, Control:Recent, Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater number of spines compared to groups WM Only:Recent, WM Only:Remote, Control:Recent, and Control:Remote (p < 0.05). Group WM/OP:Recent had significantly greater number of spines compared to groups WM Only:Recent and Control:Recent (p < 0.05).Spine density. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and spine density as the dependent variable revealed no main effects. Planned Fisher's LSD post-hoc comparisons revealed group WM/RAM:Recent had significantly greater spine density compared to group Control:Recent (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and spine density as the dependent variable revealed no main effects. A significant interaction between behavior X time was found. Fisher's LSD post-hoc comparisons revealed group WM/RAM:Recent had significantly greater spine density compared to groups WM Only:Recent, WM Only:Remote, WM/RAM:Remote, and Control:Recent (p < 0.05). Group WM/OP:Recent had significantly greater spine density compared to group Control:Recent (p < 0.05). Group Control:Remote had significantly greater spine density compared to group Control:Recent (p < 0.05).Summary of ACC findings. Group WM/RAM displayed the greatest and most consistent dendritic complexity in the ACC. At the recent time point, group WM/RAM was the sole group to show significantly increased dendritic complexity in apical dendrites compared to the control group.Figure Number of branches. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of branches as the dependent variable revealed a main effect of behavior with group WM/RAM displaying the greatest number of branches (38). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of branches compared to every other behavioral group (p < 0.05). Group WM/RAM:Remote had significantly greater number of branches compared to groups WM Only:Recent, WM Only:Remote, WM/RAM:Recent, Control:Recent, and Control:Remote (p < 0.05). Group WM/OP:Recent had significantly greater number of branches compared to group WM/OP:Remote (p < 0.05). Group WM/OP:Remote had significantly greater number of branches compared to groups WM/RAM:Recent, Control:Recent, and Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of branches as the dependent variable revealed a main effect of behavior with group WM/RAM displaying the greatest number of branches (16). A significant interaction between behavior X time was found . Fisher's LSD post-hoc analyses revealed group WM/RAM:Remote had significantly greater number of branches compared to groups WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05). Group WM/OP:Recent had significantly fewer number of branches compared to groups WM/RAM:Remote, WM/OP:Remote (p < 0.05). Group WM/OP:Remote had significantly greater number of branches compared to group WM Only:Remote, WM/OP:Recent, and Control:Recent (p < 0.05).Dendritic length. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and dendritic length as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest dendritic length (2259 \u03bcm). A significant interaction between behavior X time was found . Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater dendritic length compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater dendritic length compared to group Contol:Remote (p < 0.05). Group WM/OP:Remote had significantly greater dendritic length compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and dendritic length as the dependent variable revealed no main effects. Planned Fisher's LSD post-hoc comparisons revealed group WM/OP:Remote had significantly greater dendritic length compared to groups WM Only:Remote and Control:Recent. Group Control:Recent had significantly less dendritic length compared to groups WM Only:Recent and WM/OP:Remote (p < 0.05).Number of spines. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of spines as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest number of spines (1793). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of spines compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05). Group WM/RAM:Remote had significantly greater number of spines compared to group WM Only:Recent, WM Only:Remote, WM/OP:Reent, Control:Recent, and Control:Remote (p < 0.05). Group WM/OP:Recent had significantly fewer number of spines compared to groups WM/RAM:Recent, WM/RAM:Remote and WM/OP:Remote (p < 0.05). Group WM/OP:Remote had significantly greater number of spines compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and number of spines as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest number of spines (647). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater number of spines compared to group Control:Recent (p < 0.05). Group WM/RAM:Remote had significantly greater number of spines compared to groups WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05). Group WM/OP:Recent had significantly fewer number of spines compared to groups WM/RAM:Remote and WM/OP:Remote (p < 0.05). Group WM/OP:Remote had significantly greater number of spines compared to groups WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05).Spine density. Figure Apical. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and spine density as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest spine density (0.812). Fisher's LSD post-hoc analyses revealed group WM/RAM:Remote had significantly greater spine density compared to groups WM Only:Recent, WM Only:Remote, WM/OP:Recent, Control:Recent, and Control:Remote (p < 0.05).Basal. A Two-Way ANOVA with Behavioral group and time (Recent or Remote) as the fixed factors and spine density as the dependent variable revealed a main effect of behavior , with group WM/RAM displaying the greatest spine density (0.812). Fisher's LSD post-hoc analyses revealed group WM/RAM:Recent had significantly greater spine density compared to group Control:Recent (p < 0.05). Group WM/RAM:Remote had significantly greater spine density compared to groups WM/OP:Recent and Control:Recent (p < 0.05).Summary of CA1 findings. Group WM/RAM displayed the greatest dendritic complexity in the CA1. Group WM/RAM was the only group to show increased dendritic complexity at the recent time point. Group WM/RAM also showed persistent increases in the dendritic complexity characteristics analyzed as this group was found to have these characteristics significantly increased from the Control group at the remote time point as well. Group WM/OP:Remote consistently showed increases in dendritic complexity at the remote time point.A great deal of human research supports the idea of a time-limited role for the hippocampus in memory storage . Future behavioral studies utilizing one-day training procedures are underway so that early structural changes in the ACC and CA1 can be examined. A one-day training procedure would also help to diminish delay differences between the end of training on a behavioral task and neuron analysis. In the present study, there was a difference in the delay between the end of behavioral training and neuron analysis in rats trained on one or two tasks. Training on the RAM or OP tasks entailed 5 days of training followed by a day of rest then sacrifice. Rats trained on only the WM task had 6 days of rest prior to sacrifice. This difference could influence dynamic dendritic characteristics such as spine density. This difference may become more substantial when examining recent vs. remote time points.Neuron reconstruction data showed robust increases in dendritic complexity in the ACC and CA1 at recent and remote time points in groups trained on two hippocampal-dependent tasks. These results suggest competing hippocampal-dependent memories may result in more pronounced, or accelerated, increases in dendritic complexity in the ACC. Without hippocampal-dependent memories competing for hippocampal processing space, structural changes may be less distinct, or take a longer amount of time to come about. The introduction of a multiple memory behavioral procedure presents an innovative method through which structural changes associated with memory storage can be examined. Introducing variations in the type and number of tasks used during training provides an opportunity to examine and contrast morphological differences throughout the consolidation process, shedding light on the processes underlying remote memory storage.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."} +{"text": "Aquilegia pubescens and A. canadensis. The correct citation is: Noutsos C, Perera AM, Nikolau BJ, Seaver SMD, Ware DH (2015) Metabolomic Profiling of the Nectars of Aquilegia pubescens and A. canadensis. PLoS ONE 10(5): e0124501. doi:10.1371/journal.pone.0124501There is an error in the title. The correct title is: Metabolomic Profiling of the Nectars of The images for Figs Please see the corrected"} +{"text": "TP53 in gastric cancer (GC) has been investigated world-widely, but a comparison of mutation spectrum among GCs from various regions in the world are still sparsely documented. In order to identify the difference of TP53 mutation spectrum in GCs in Eastern Europe and in East Asia, we sequenced TP53 in GCs from Eastern Europe, Lujiang (China), and Yokohama, Kanagawa (Japan) and identified the feature of TP53 mutations of GC in these regions.Mutation spectrum of TP53. Mutation patterns were categorized into nine groups: six base substitutions, insertion, deletion and deletion-insertion. Within G:C\u2009>\u2009A:T mutations the mutations in CpG and non-CpG sites were divided. The Cancer Genome Atlas data having somatic mutation list of GCs from Whites, Asians, and other ethnicities were used as a reference for our data.In total, 689 tissue samples of GC were analyzed: 288 samples from East European populations , 268 from Yokohama, Kanagawa, Japan and 133 from Lujiang, Anhui province, China. DNA was extracted from FFPE tissue of Chinese, East European cases; and from frozen tissue of Japanese GCs. PCR products were direct-sequenced by Sanger method, and in ambiguous cases, PCR product was cloned and up to 8 clones were sequenced. We used No. NC_000017.11(hg38) as the reference sequence of The most frequent base substitutions were G:C\u2009>\u2009A:T transition in all the areas investigated. The G:C\u2009>\u2009A:T transition in non-CpG sites were prominent in East European GCs, compared with Asian ones. Mutation pattern from TCGA data revealed the same trend between GCs from White (TCGA category) vs Asian countries. Chinese and Japanese GCs showed higher ratio of G:C\u2009>\u2009A:T transition in CpG sites and A:T\u2009>\u2009G:C mutation was more prevalent in Asian countries.The divergence in mutation spectrum of GC in different areas in the world may reflect various pathogeneses and etiologies of GC, region to region. Diversified mutation spectrum in GC in Eastern Europe may suggest GC in Europe has different carcinogenic pathway of those from Asia.The online version contains supplementary material available at 10.1186/s41021-022-00257-y. GC inciay/home) . In mostay/home) , are knoay/home) .The time trends and geographic variation reflect the difference in causative factors of GC, such as differences in environmental factors, lifestyle, infection, traditional foods, and salty diet, as well as the genetic structure of individual populations.TP53 mutations, the most prevalent gene mutations found in human tumors, has provided important clues for environmental carcinogenesis [TP53 mutations in various human cancers in specific settings, such as tobacco smoking, UV damage, and aflatoxin exposure [TP53 in aflatoxin B-related hepatocellular carcinoma. These specific mutation spectra are currently being recapitulated as mutation signatures based on next-generation sequencing data, including single base substitution (SBS) 4, SBS 7, and SBS24 corresponding to tobacco, UV, and aflatoxin B, respectively [The spectrum of somatic ogenesis . In the exposure . For exaectively \u20138.TP53 database was created from voluminous mutation spectrum data in various cancers collected from different populations around the world. The IARC TP53 database by the NCI and other published reports indicated that the TP53 mutation observed in GC mainly involves G:C\u2009>\u2009A:T transitions [The nsitions .TP53 mutations in GC have mainly been found in Asians, Whites, Blacks, American Indians, Alaskan Natives, and Hawaiian natives.Although there are anecdotal reports on GC mutations from Poland , 11, infTP53 mutations in GC samples from East European countries and compared these with mutation spectra observed in GC samples from East Asian countries (China and Japan).In this report, for the first time, we characterized considerable numbers of In total, 689 GC tissue samples from three populations worldwide were analyzed: 288 samples from the European population , 268 from Japan, and 133 from China. The clinical profiles of the patients are summarized in Table\u00a0The pathology archives of GC formalin-fixed paraffin-embedded tissues (FFPE) were collected from three countries in Eastern Europe and Lujiang County, Anhui Province, China. Fresh GC tissues were obtained from the Pathology Department of Kanagawa Cancer Center, Yokohama. DNA was extracted from the FFPEs using the QIAamp DNA FFPE Tissue Kit , 13, whiTP53 gene sequencing was performed by direct sequencing using a polymerase chain reaction (PCR) product amplified using respective primer sets for each exon. Fragments covering exons 2 to 11 and the boundary regions of the TP53 gene were amplified via PCR using the HotStarTaq DNA polymerase (Qiagen). The PCR products were purified with Exo-SAP-IT and sequenced via the Sanger method using the BigDye Terminator Cycle Sequencing Reaction Kit, ver.3.1 and ABI 3130xL Genetic Analyzer (Thermo Fisher Scientific). PCR products exhibiting multiple bands were sequenced after subcloning them into a pGEM-T Easy vector system . Up to eight clones were sequenced, particularly upon confirming the presence of insertion/deletion mutations. The primers used are listed in Table STP53 reference sequence (Accession No. NC_000017.11(hg38 and GRCh38)). For the DNA samples from FFPEs that were difficult to amplify, and when amplification was not successful, the primer designs were modified to amplify different segments of TP53. The resulting sequences were assigned to the reference sequences. DNA mutations were described according to the international guidelines for gene nomenclature [nclature . In thisTP53 mutation patterns were categorized as follows: G:C\u2009>\u2009A:T, A:T\u2009>\u2009G:C, G:C\u2009>\u2009C:G, G:C\u2009>\u2009T:A, A:T\u2009>\u2009C:G, A:T\u2009>\u2009T:A, deletion, deletion-insertion, insertion, and splice-site mutations in exons 4 to 8. G:C\u2009>\u2009A:T mutations were subclassified based on their localization in CpG or non-CpG sites. We also grouped TP53 mutations found here according to the following hotspots proposed by Hainaut P [ainaut P : c.524G\u2009TP53 mutations was drawn using cBioPortal MutationMapper [A distribution map of _mapper) to deterTP53 gene was downloaded for Caucasian (n\u2009=\u2009278) and Asian (n\u2009=\u200989) populations from the Stomach Adenocarcinoma data in cBioPortal. The downloaded dataset included 148 Caucasian and 47 Asian patients with intrasomatic mutations. The percentage of base substitution patterns obtained for each race was determined. Since the nucleotide sequence files were not available, we extracted the patterns of G\u2009>\u2009A or C\u2009>\u2009T gene mutations to determine if they were in the CpG region, and the sequences of the mutations were compared against the reference genome (GRCh38) by extracting the sequences before and after the base substitution. Base substitutions at the splice site or region were preferentially classified as splice mutations.Information on somatic mutations except for synonymous mutations in the TP53 mutations. Ninety-six substitution types and sequence contexts were counted for each population. The percentage of each of the 96 substitution types was calculated from the total number of substitutions in each population. The SBS for each population was estimated using Signal [Substitutions in the coding sequence were determined from the somatic res.com) .This study was a retrospective, anonymous, and non-intervention study, and informed consent from the patients was waived. The research plan was agreed upon by all researchers and approved by the IRB of the Hamamatsu University School of Medicine (G-260 and 20-110), Kanagawa Cancer Center, and the Ethical Committee of the University of Medicine and Pharmacy of Targu-Mures, Romania (Agreement no. 124/28.07.2016).Statistical analyses were performed using the chi-square test, t-test, and Fisher\u2019s exact test with JMP, ver.11.2 test, p\u2009=\u20092\u2009\u00d7\u200910\u2212\u20095). Japanese patients were older than Chinese patients . There were no significant differences in sex among the three populations had TP53 mutations, and 404 (59%) were wild-type. The ratios of mutated cases were 29.5% (85/288), 57.1% (76/133), and 46.3% (124/268) in Eastern Europe, China, and Japan, respectively among the three regions; when the prevalence in Japan and China were combined (as East Asia), the prevalence was greater in East Asia than in Eastern Europe .A total of 689 genomic samples were successfully analyzed for TP53 were relatively evenly distributed among the three groups. Those at CpG sites involved several mutation assemblies, such as R175H and R248W/Q in Eastern Europe and Japan, and R273C/H in China for the three areas are presented. Mutation-accumulated codons, such as R175H/G, R248W/Q, and R273C/H/P, were observed in each population in five to ten cases , China (17.8%), and Japan 15.6%) (\u03c7.6% (\u03c72 tp\u2009=\u20090.04) than in East Asian countries. On the other hand, A:T\u2009>\u2009G:C showed a significantly higher prevalence in China and Japan than in Eastern Europe, especially in diffuse-type GCs in the diffuse type of GC in Eastern Europe, in which the prevalence of G:C\u2009>\u2009A:T at non-CpG sites was significantly higher 30.3%) [TET genes and methylation erasers were downregulated in mice with gastric inflammation, causing aberrant methylation [TP53 in East Asia, specifically G:C\u2009>\u2009A:T at CpG sites in GC, reflects the common infectious status of the stomach there. The increased ratio of G:C\u2009>\u2009T:A in GC in East Asian countries may also reflect increased oxyradical DNA damage caused by continued inflammation in the stomach. Non-environmental mechanisms may also play a role in the process. A considerable number of G:C\u2009>\u2009A:T mutations were also found in Eastern European cases, and the issue of whether G:C\u2009>\u2009A:T mutations at CpG and non-CpG sites are related to the histological type of GC is still an enigma.The higher frequency of G:C\u2009>\u2009A:T mutations at CpG sites in GC in Asia probably reflects chronic inflammation, specifically, chronic gastritis caused by chronic nfection \u201327. Chronfection , 29. G:Cnfection \u201332. Infli (CagA) . Recentlhylation . Thus, tTP53 mutations at CpG and non-CpG sites reminds us of several aspects of environmental gastric carcinogenesis [TP53 mutations at non-CpG sites had a more traditional dietary history, including nitrite, protein, and fat, particularly from animal sources, than in those with mutations at CpG sites. In addition, nitric oxide induced by gastritis may be used to produce N-nitroso compounds [N-Nitroso compounds can also be taken up by the human body through water, drugs, cosmetics, and tobacco. Since a successful experimental model of GC using N-nitroso compounds has been established [N-nitroso compounds [N-Nitroso compounds can generate alkylated guanine adducts, which contribute to G:C\u2009>\u2009A:T transitions. In contrast, deamination after the nitrosation of guanine and adenine produces xanthine and hypoxanthine, respectively. Hypoxanthine induces A:T\u2009>\u2009G:C transitional mutations [N-nitroso compounds remains a challenge. The generation of DNA adducts has been attributed to alkylating agents hypothetically [The implication of the difference in ogenesis . The epiompounds . N-Nitroablished , many inompounds . N-Nitroutations . These autations ; howeveretically \u201342; howeTP53 in understudied populations may encourage us to pursue the etiological varieties of GC in populations worldwide. We were not able to explain the exact causes of A:T\u2009>\u2009G:C in GC samples from East Asia. Hongyo et al. have already shown this mutation spectrum in their summary tables and stated that A:T\u2009>\u2009G:C mutations are prevalent in \u201cOriental\u201d regions but did not expound much on this finding [HPRT locus in CHO-K1 cells [The mutation spectrum of finding . Lee DH K1 cells . Some enK1 cells , may alsK1 cells \u201342; howeTP53 mutations, and the sample size was smaller than that generated by the international consortium. As such, hundreds of tumors from Eastern European residents were not compared with those from East Asian residents. It is necessary to confirm our findings by analyzing a large-scale sample set. Second, the designated \u201cChinese\u201d samples originated from a single institution only; thus, generalizing our findings in this population for Chinese patients with GC would be inappropriate, considering the extensive variations in environmental exposures for these patients. Third, the FFPE quality may not be perfectly controlled. No central pathological diagnosis was made. Primer coverage was not the same; thus, the detectability of splice site mutations may have differed. Currently, data on somatic mutations in human cancers using next-generation sequencing are accumulating, and the implications of our results may need to be re-evaluated. The mutation spectrum of ARID1A, which is currently the most prevalent mutated gene in all cancers, is also of interest.Our study has several obvious limitations. First, we only studied p\u2009=\u20090.04 in the two groups, East Europe vs. Asian countries). This apparent difference in the mutation spectrum in different histological subtypes is interesting; however, we must be careful in accepting this finding because we did not use a centralized pathological diagnosis system in this study. In each region, the numbers of blocks that were pathologically investigated were very different, and the method of histological subtyping differed among pathologists from each region. A more comprehensive approach, such as Massive Parallel Sequencing accompanied by centralized pathological assessment, will yield greater information.Another problem is the subjective bias of histological typing of GC in these three regions. G:C\u2009>\u2009A:T mutation prevalence was high (69.6%), especially in the diffuse type of GC in Eastern Europe, in which the ratio of G:C\u2009>\u2009A:T at non-CpG sites was significantly high (30.3%) . Mutation-distribution maps were created using the cBioPortal mutation mapper . Black dots indicate truncating mutations (nonsense and frameshift mutations). The light purple dot indicates a silent mutation. P53_TAD, TP53 transcriptional activation domain; P53, TP53 DNA-binding domain; P53 tetramer, TP53 tetramer domain.Additional file 2: Supplementary Figure S2.TP53 mutation types in the intestinal and diffuse types of GC samples from Eastern Europe, China, and Japan (exon 4-8). The pie graphs show the percentages of the mutations, including missense (blue), nonsense (orange), and silent mutations (gray), deletions (del) (yellow), deletion-insertion (delins) (light blue), insertions (ins) (light green), and splice site mutations (dark blue) in TP53 in GC samples from Eastern Europe, China, and Japan. The prevalence of silent mutations (gray) in diffuse-type GCs was significantly different between Europe and Asia (P\u2009<\u20090.01). * Statistically significant difference (p\u2009<\u20090.05).Additional file 3: Supplementary Figure S3. Mutation spectra in intestinal and diffuse-type GCs in East Europe, China, and Japan. The TP53 mutations were classified into six types of single nucleotide substitutions, as well as deletions (del), insertions (ins), deletion-insertion (delins), and splice mutations. The G:C\u2009>\u2009A:T transition was subdivided into G:C\u2009>\u2009A:T at CpG and non-CpG sites. Each spectrum is shown in the pie graph as follows: G:C\u2009>\u2009A:T at CpG sites (blue), G:C\u2009>\u2009A:T at non-CpG sites (orange), A:T\u2009>\u2009G:C (gray), G:C\u2009>\u2009C:G (yellow), G:C\u2009>\u2009T:A (light blue), A:T\u2009>\u2009C:G (light green), A:T\u2009>\u2009T:A (dark blue), del (brown), delins (dark gray), ins (light brown), and splice mutations (light navy). The prevalence of G:C\u2009>\u2009A:T at non-CpG sites (orange) in diffuse-type GCs in Asia was significantly different from that in Eastern Europe (p\u2009<\u20090.05). * Statistically significant difference (p\u2009<\u20090.05).Additional file 4: Supplementary Figure S4. Designations of populations based on TCGA classification. The majority of the data were from the \u201cWhite\u201d population. The \u201cAsian\u201d population was not defined, especially whether they were only residing in Asia or not. NA, not available.Additional file 5: Supplementary Figure S5. Mutation spectrum of the TP53 gene in GC in each population. Six substitution types are depicted in the bar graph as follows: C\u2009>\u2009A (light blue), C\u2009>\u2009G (black), C\u2009>\u2009T (red), T\u2009>\u2009A (gray), T\u2009>\u2009C (yellow-green), and T\u2009>\u2009G .Additional file 6: Table S1. Primers for PCR amplification of TP53 gene. Table S2. Histological type and TP53 mutation status. Table S3. Mutation distribution in TP53 (exon 4\u20138). Table S4. Mutation functions of TP53 (exon 4-8) in Eastern Europe, China and Japan. Table S5. Mutation spectrum of TP53 (exon 4\u20138) in Eastern Europe, China and Japan. Table S6. Hotspot mutation in Eastern Europe, China and Japan."} +{"text": "Scientific Reportshttps://doi.org/10.1038/srep19401, published online 14 January 2016Correction to: This Article contains an error in Equation 15, where the should read:An extra note of caution is warranted regarding the variances"} +{"text": "Funding statement. Several fundings were not included. The correct Funding statement appears below.In the published article, there was an error in the \u201cThis work was supported by U.K. Research and Innovation Biotechnology and Biological Sciences Research Council Grants BBS/E/I/00001825, BBS/E/I/00007030, BBS/E/I/00007031, BB/S01506X/1, BBS/E/I/00002529, BBS/E/I/00007039, BBS/E/I/00007032, BB/N002598/1 and BB/V019031/1. The authors would also like to acknowledge the Pirbright Flow Cytometry facility and support through the Core capability grant (BBS/E/I/00007039).\u201dThe authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."} +{"text": "Biol. Open (2020) 9, bio050435 (doi:10.1242/bio.050435)There was an error published in In The authors apologise to readers for the error, which does not impact the results or conclusions of this paper."} +{"text": "Interface Focus12, 20220020. (Published online 12 August 2022). (https://doi.org/10.1098/rsfs.2022.0020)The Funding section of the article \u2018Mathematical modelling of oxygen transport in a muscle-on-chip device\u2019, should read as follows:This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no. 801423. This research was funded in whole, or in part, by the Engineering and Physical Sciences Research Council (EPSRC) (grant nos. EP/R029598/1 and EP/T008806/1). For the purpose of open access, the author has applied a creative commons attribution (CC BY) licence to any author accepted manuscript version arising."} +{"text": "Shallow groundwater (GW), defined as the water table of unconfined or perched aquifers that is near enough to the land surface to influence the vadose zone and the surface soil moisture, impacts land surface water, energy, and carbon cycles by providing additional moisture to the root zone via capillary fluxes. Although the interactions of shallow GW and the terrestrial land surface are widely recognized, incorporating shallow GW into the land surface, climate, and agroecosystem models is not yet possible due to the lack of groundwater data. Groundwater systems are affected by various factors, including climate, land use/land cover, ecosystems, GW extractions, and lithology. Although GW wells are the most direct and accurate way of monitoring water table depths at point scales, upscaling GW levels from point scale to areal or regional scale poses significant challenges.Here, we provide high spatiotemporal resolution global maps of the terrestrial land surface areas influenced by shallow GW from mid-2015 to 2021 (a separate NetCDF file for each year) in a 9 km spatial and daily temporal resolution. We derived this data from NASA's Soil Moisture Active Passive (SMAP) mission spaceborne soil moisture observations with a temporal resolution of 3 days and approximately 9 km grid resolution. This spatial scale corresponds to SMAP's \"Equal Area Scalable Earth\" (EASE) grids. The central assumption is that the monthly moving average of soil moisture observations and their coefficient of variation are sensitive to shallow GW regardless of the prevailing climate. We process the Level-2 enhanced passive soil moisture SMAP (SPL2SMP_E) product to detect shallow GW signals. The presence of shallow GW data is calculated by an ensemble machine learning model, which is trained using simulations from a variably saturated soil moisture flow model (Hydrus-1D). The simulations span various climates, soil textures, and lower boundary conditions.The spatiotemporal distribution of shallow GW data based on SMAP soil moisture observations is provided for the first time with this dataset. The data are of value in a wide variety of applications. The most direct use is in climate and land surface models as lower boundary conditions or as a diagnostic tool to verify model results. Some other applications may include flood risk analyses and regulation, identifying geotechnical issues such as shallow GW-triggered liquefaction, global food security, ecosystem services, watershed management, crop yield, vegetation health, water storage trends, and tracking mosquito-borne diseases by identifying wetlands, among other applications. Specifications Table\u2022An observation-based database representing shallow groundwater presence globally is provided. Given the high spatiotemporal resolution, the shallow GW dataset may contribute to the efforts of integrating GW into surface flux models as a calibration or diagnostic tool to assess the validity of such models. Moreover, the dataset helps reduce the model biases originating from the additional water added to the root zone due to shallow GW presence.\u2022The dataset presented here can potentially be helpful in a wide variety of research areas, including flood risk analyses and regulation, identifying geotechnical issues such as liquefaction, global food security, ecosystem services, watershed management, crop yield, vegetation health, water storage trends, and global distributions of wetlands.\u2022Another, more direct, use of the dataset may be to use it as LBC to the surface flux models. This option may improve the soil moisture flux simulation accuracies while reducing the computational cost of such models. Adopting this shallow GW database based on observations, as a driver to control the model LBC allows modelers to solve the Richards equation in 1-D instead of 3-D without losing the accuracy of results.1Shallow GW provides additional water to ecosystems and the land surface. The additional water resulting from the coupling between GW and the surface not only affects evapotranspiration but also has the potential to modify ecosystems and components of water, energy, and carbon cycles. The lack of global-scale shallow GW data with high spatial and temporal resolution hinders our understanding of terrestrial water, energy, carbon, and water cycle components.The theoretical background on generating the shallow GW dataset was explained in detail in 2Shallow GW data is provided in multidimensional NetCDF file contents. A separate NetCDF file is produced for each year from mid-2015 to 2021. Each data file covers the entire temporal range from January 1st to December 31st, except the file for the year 2015, which covers only between June 1st to December 31st due to SMAP data availability.The dataset has a \u201cShallow Groundwater Presence\u201d variable, indicating through a binary variable whether the region is under shallow groundwater influence or not. If this variable equals 1, the given pixels are under shallow GW influence. A pixel value of -9999 value indicates that there is no shallow GW influence or that there is not sufficient soil moisture data available to detect shallow GW presence.File name: ShallowGW2015.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:06/01/2015; End date:12/31/2015Temporal resolution: 1 dayFile name: ShallowGW2016.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2016; End date:12/31/2016Temporal resolution: 1 dayFile name: ShallowGW2017.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2017; End date:12/31/2017Temporal resolution: 1 dayFile name: ShallowGW2018.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2018; End date:12/31/2018Temporal resolution: 1 dayFile name: ShallowGW2019.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2019; End date:12/31/2019Temporal resolution: 1 dayFile name: ShallowGW2020.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2020; End date:12/31/2020Temporal resolution: 1 dayFile name: ShallowGW2021.ncFiletype: NetCDF fileSpatial extent: Latitude: -180:180 Degrees North; Longitude: -85:85 Degrees EastSpatial resolution: 9 kmTemporal coverage: Start date:01/01/2021; End date:12/31/2021Temporal resolution: 1 day3To produce the shallow GW dataset, we applied a supervised EML model on SMAP L2 soil moisture observations. Surface soil moisture simulations representing SMAP observations are used to train the EML model . Below, 3.1The SMAP sensors capture L-band microwave emissions globally with approximately 3 days temporal and 36 km spatial resolution. We use the radiometer-based level 2 enhanced passive soil moisture (SPL2SMP_E Version 5) product, which has a 9 km grid resolution derived from a 36 km spatial resolution 3.2The Hydrus-1D model, which solves the Richards equation for variably saturated soil water flow, is used to simulate the surface soil moisture, mimicking SMAP observations. The model is driven by the Global Precipitation Measurement (GPM) mission precipitation data boundary conditions at five different depths, representing constant water table depths from 0.5 m to 2.5 m, in increments of 50 cm, are used. In addition, a simulation with free drainage lower boundary conditions is done. The total soil profile domain thickness is taken as 3 meters, but only the top 5 cm of the simulations are considered to represent SMAP soil moisture observations. The model simulations cover five years period from 2015 to 2019. We use the first year as the model spin-up period. The results of that year are not used in the data analyses.3.3The gentle adaptive boosting (GentleBoost), a variant of the adaptive boosting ensemble machine learning (EML) technique, is used to classify whether the surface soil moisture data is affected by shallow groundwater. To develop the EML method, about 1.2 million soil moisture data points are used in model training, and about 0.8 million data points are used in model testing. The daily coefficient of variation, minimum, maximum, and average surface soil moisture values are used as model predictors. A 30-day moving window average is used to calculate each predictor. We find that using a monthly time window width provides a sufficient number of sample points allowing us to analyze the soil moisture signals in a statistically meaningful way. At the same time, a 30-day window width does not smooth the shallow groundwater signals too much.Once the EML model is trained, we apply it to the SMAP observations covering the period from mid-2015 to the end of 2021. We adopt a data correction scheme as the last step before the final dataset, as recommended by The shallow GW dataset is evaluated against three datasets. First, we compare to baseflow estimations in the southeast US. Second, we check consistency with global scale wetland distributions estimated based on a global scale GW model outputs https://www.elsevier.com/authors/journal-authors/policies-and-ethics.The current work does not involve human subjects, animal experiments, or any data collected from social media platforms and meets the ethical requirements for publication in Data in Brief as stated in Mehmet Evren Soylu: Conceptualization, Investigation, Formal analysis, Methodology, Validation, Visualization, Writing \u2013 original draft; Writing \u2013 review & editing; Rafael L. Bras: Supervision, conceptualization, Writing \u2013 review & editing.The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."} +{"text": "In \u201cImproving Pelvic Floor Muscle Training Adherence Among Pregnant Women: Validation Study\u201d :e30989), the following errors were noted.1. Abstract:In the originally published paper, the first sentence in the abstract was stated asMobile health apps, for example, the T\u00e4t, have been shown to be potentially effective in improving pelvic floor muscle training (PFMT) among women, but their effectiveness in pregnant women was limited.This has been corrected to:Mobile health apps, for example, the T\u00e4t, have been shown to be potentially effective in improving pelvic floor muscle training (PFMT) among women, but they have not yet been studied among pregnant women.2. Methods, Intervention Mapping:The originally published paper was missing two references for this statement: The outcomes of the intention are self-efficacy (17 questions) and adherence (6 questions).This has been corrected to:The outcomes of the intention are self-efficacy (17 questions) (41) and adherence (6 questions) (42). 3. Methods, Cross-Sectional Study:The originally published paper was missing two references for this statement:The findings from this study provided input for the content of their educational videos and short notes on PFMT, which were captured as frequently asked questions (FAQ).This has been corrected to:The findings from this study provided input for the content of their educational videos and short notes on PFMT which were captured as frequently asked questions (FAQ).4. Results:The originally published paper stated the following in row 1, column 2 of Table 5:1.System credibility-expertise and authority.2. Primary support-Virtual rehearsal principleThis has been corrected to:System credibility-expertise and authority5. Results:The originally published paper stated the following as the title for the first column of Table 5:COM-B model and behavioral change techniques incorporated in the mHealth app.This has been corrected to:COM-B model and features of the mHealth app.6. Discussion:The originally published paper was missing one reference for this statement:The PSD component of the system\u2019s credibility and trustworthiness, with the expertise involved in the development, may add to the user\u2019s sense of safety and reliability regarding the KEPT app.This has been corrected to:The PSD component of the system\u2019s credibility and trustworthiness (55), with the expertise involved in the development, may add to the user\u2019s sense of safety and reliability regarding the KEPT app.6. References:In the corrected paper, the following citations have been newly added to the Reference List. As these new references have been numbered per the order of their in-text citations, the remaining citations in the reference list have been renumbered accordingly. 41. Sacomori C, Cardoso FL, Porto IP, Negri NB. The development and psychometric evaluation of a self-efficacy scale for practicing pelvic floor exercises. Brazilian Journal of Physical Therapy; 2013. [doi: 10.1590/S1413-35552012005000104] 42. Newman-Beinart NA, Norton S, Dowling D, Gavriloff D, Vari C, Weinman JA, Godfrey EL. The development and initial psychometric evaluation of a measure assessing adherence to prescribed exercise: the Exercise Adherence Rating Scale (EARS). Physiotherapy, 103(2); 2017, 180\u2013185. [doi: 10.1016/j.physio.2016.11.001]45. Alagirisamy P, Mohd Sidik S. Pelvic Floor Muscle Exercises During and After Pregnancy. Universiti Putra Malaysia Press Serdang 2020.46. Bo K, Berghmans B, Morkved S, Van Kampen M. Evidence-Based Physical Therapy for the Pelvic Floor-E-Book: Bridging Science and Clinical Practice, 2nd ed. London, UK: Elsevier Health Sciences; 2014. 3.55. Asklund I, Nystr\u00f6m E, Sj\u00f6str\u00f6m M, Umefjord G, Stenlund H, Samuelsson E. Mobile app for treatment of stress urinary incontinence: A randomized controlled trial. Neurourol Urodyn 2017 Jun;36(5):1369-1376. [doi: 10.1002/nau.23116] [Medline: 27611958]The correction will appear in the online version of the paper on the JMIR Publications website on April 11, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."} +{"text": "Cell Death and Disease 10.1038/cddis.2016.292, published online 13 October 2016Correction to: The original version of this article unfortunately contained an error in fig. 3e. The authors apologize for the error. The correct figure can be found below."} +{"text": "To our knowledge, there is no Parkinson\u2019s disease (PD) gait biomechanics data sets available to the public.This study aimed to create a public data set of 26 idiopathic individuals with PD who walked overground on ON and OFF medication.Their upper extremity, trunk, lower extremity, and pelvis kinematics were measured using a three-dimensional motion-capture system . The external forces were collected using force plates. The results include raw and processed kinematic and kinetic data in c3d and ASCII files in different file formats. In addition, a metadata file containing demographic, anthropometric, and clinical data is provided. The following clinical scales were employed: Unified Parkinson\u2019s disease rating scale motor aspects of experiences of daily living and motor score, Hoehn & Yahr, New Freezing of Gait Questionnaire, Montreal Cognitive Assessment, Mini Balance Evaluation Systems Tests, Fall Efficacy Scale-International\u2013FES-I, Stroop test, and Trail Making Test A and B.https://figshare.com/articles/dataset/A_dataset_of_overground_walking_full-body_kinematics_and_kinetics_in_individuals_with_Parkinson_s_disease/14896881).All data are available at Figshare (This is the first public data set containing a three-dimensional full-body gait analysis of individuals with PD under the ON and OFF medication. It is expected to contribute so that different research groups worldwide have access to reference data and a better understanding of the effects of medication on gait. Several studies seek to understand the gait kinematics of Parkinson\u2019s disease (PD) patients to identify which parameters are altered with the disease. Compared to healthy individuals in general, it is known that these patients tend to present changes in the spatiotemporal parameters of gait, such as a decrease in step length, reduction in gait speed, and difficulty in the start and stop movement . HoweverA few gait datasets in PD are available in the literature . AlthougThe data collection was performed in the Laboratory of Biomechanics and Motor Control at the Federal University of ABC, Brazil. The local Ethics Committee approved this study (protocol number 21948619.6.0000.5594), and all patients signed a consent form before collecting data. The patients were on a stable dose of l-DOPA for at least 1 month. The idiopathic individuals with PD participated in two experimental sessions for 1 week, one in the ON condition of the medication and the other in the OFF condition. To be considered ON condition, participants had taken dopaminergic medication 1 h before starting the session to ensure dose stabilization. In the OFF condition, the participants spent at least 12 h without medication for Parkinson\u2019s disease . The ord2, Hoehn & Yahr (H&Y) scale between 1 and 4, and 13 with freezing of gait (FoG). Inclusion criteria were the absence of neurological or physical dysfunctions other than those associated with PD and no diagnosed vestibular, visual, or somatosensory dysfunctions as self-declared.A convenience sample of 26 idiopathic individuals with PD was recruited to participate in this study. The patients were recruited from local communities and included local neighborhoods and ambulatory movement disorders. The patients were interviewed to collect information about their demographic characteristics, socio-cultural characteristics, and overall health condition. Their ages varied from 44 to 81 years, body masses from 53.3 to 94.6 kg, heights from 151.5 to 179.0 cm, body-mass indexes (BMI) from 19.2 to 34.3 kg/mAll gait trials were performed barefoot, and the participants wore comfortable shorts (women wore sports bras). Participants were asked to perform overground walking trials at a self-selected comfortable speed. The marker-set protocol adopted for this study comprised: (a) in the lower limb, 26 anatomical reflective markers ; and (b)1.The researcher explained to each patient the process of data collection. The patient was informed that he or she would be monitored during the data collection. There should not be any verbal communication during the trials, but he or she could interrupt the data collection if desired. Furthermore, that assistance would be given if necessary.2.After these explanations, the patient signed the informed consent form.3.The researcher interviewed the subject to collect information about his or her clinical data, medication, and disease diagnosis.4.At the beginning of each session, two experienced physiotherapists in movement disorders applied the following scales: Unified Parkinson\u2019s Disease Rating Scale motor aspects of experiences of daily living (UPDRS-II) and motor aspects (UPDRS-III) , H&Y Ho, New Fre5.Participants rested for 10 min.6.Markers were placed directly onto the skin of the full body .7.X-axis of the laboratory coordinate system (LCS) . A templ8.After the calibration trial and a familiarization period, participants were instructed to walk at a comfortable self-selected speed along a 20-m walkway. Participants performed 20 trials. The participants did not use any aid during the trials.Standard gait analysis was collected using a motion-capture system that had 12 cameras , five force platforms embedded in the floor. The kinematic data were acquired at 150 Hz, and the data on ground-reaction forces were acquired at 300 Hz using a motion-capture system .The data processing was performed using Cortex 6.0. Visual 3D software version 6.00.33 performed all kinematics and kinetics calculations. To enable users to process the data in the Visual 3D software, a Visual 3D pipeline file is available at Figshare. The analysis of the overground trials considered only those files that contained at least one full gait cycle (stance and swing phase) detected by kinematics. Heel strike and toe-off were calculated bilaterally using the horizontal velocity of the heel marker method . The pub1 in both c3d and ASCII file formats. The data set comprises a file with metadata, and separate text files were generated for the markers, angular kinematics, and force signals at 150 Hz. The clinical characteristics of the patients are presented in The data is available at FigshareThe metadata file named PDGinfo.txt contains 61 information from each patient\u2019s anamnesis and clinical scales. Here is the coding for the metadata:1.ID: the file name of the stabilography trial .2.Gender: gender (F or M).3.Age: patient\u2019s age in years.4.Height (cm): height in meters .5.Weight (kg): weight in kilograms .6.2): body mass index in kg/m2.BMI (kg/m7.Ortho-Prosthesis: name of the orthosis or prosthesis the subject wears (\u201cNo\u201d if the patient did not wear any orthosis or prosthesis).8.Years of formal study: years of formal education.9.Disease duration (years): year from diagnosis.10.\u20131): total daily levodopa equivalent dose in mg\u22c5day\u20131 according to L-Dopa equivalent units (mg\u22c5day11.FoG group: presence (freezers) or not (non-freezers) of freezing of gait.12.NFoG-Q (score): score of New Freezing of Gait Questionnaire.13.Initial symptoms: self-reported initial symptoms.14.Is there a family history of PD? Who?15.Do you feel improvement after using the antiparkinsonian medicine?: Yes or No.16.Have you ever had any surgery? Which?17.Any rehabilitation or physical activity?: name of the rehabilitation or physical activity performed by the patient .18.Other diseases : name of the disability of the patient (\u201cNo\u201d if the patient did not present any disability).19.Handedness: a self-reported manual preference.20.ON\u2013Hoehn & Yahr: Hoehn & Yahr score in the ON medication.21.ON\u2013MoCA: MoCA score in the ON medication.22.ON\u2013miniBESTest: miniBESTest score in the ON medication.23.ON\u2013FES-I: FES-I score in the ON medication.24.ON\u2013UPDRS-II: total score of the UPDRS-II in the ON medication.25.ON\u2013UPDRS-II\u2013walking: score of item 4\u2013walking of the UPDRS-II in the ON medication.26.ON\u2013UPDRS-III: total score of the UPDRS-III in the ON medication.27.ON\u2013UPDRS-III\u2013Rigidity: score of item 5\u2013rigidity of UPDRS-III in the ON medication.28.ON\u2013UPDRS-III\u2013Gait: score of item 12\u2013rigidity of UPDRS-III in the ON medication.29.ON\u2013PIGD or TD: Postural Instability/Gait Difficulty (PIGD) or Tremor Dominant (TD) phenotypes in the ON medication, according to 30.ON\u2013UPDRS-III asymmetry: clinical asymmetry was defined as the difference between the summed UPDRS scores of the left and right body sides (items 3.3\u20133.8 and 3.15\u20133.17). The most affected body side was the side with the highest UPDRS score in the ON medication.31.ON\u2013Stroop-I time (s): time to complete part I of the Stroop test in the ON medication.32.ON\u2013Stroop-I error: number of errors presented in part I of the Stroop test in the ON medication.33.ON\u2013Stroop-II time (s): time to complete part II of the Stroop test in the ON medication.34.ON\u2013Stroop-II error: number of errors presented in part II of the Stroop test in the ON medication.35.ON\u2013Stroop-III time (s): time to complete part III of the Stroop test in the ON medication.36.ON\u2013Stroop-III error: number of errors presented in part III of the Stroop test in the ON medication.37.ON\u2013TMTA time (s): time to complete part A of the TMT in the ON medication.38.ON\u2013TMTA error: number of errors presented in part A of the TMT in the ON medication.39.ON\u2013TMTB time (s): time to complete part B of the TMT in the ON medication.40.ON\u2013TMTB error: number of errors presented in part B of the TMT in the ON medication.41.OFF\u2013Hoehn & Yahr: Hoehn & Yahr score in the OFF medication.42.OFF\u2013MoCA: MoCA score in the OFF medication.43.OFF\u2013miniBESTest: miniBESTest score in the OFF medication.44.OFF\u2013FES-I: FES-I score in the OFF medication.45.OFF\u2013UPDRS-II: total score of the UPDRS-II in the OFF medication.46.OFF\u2013UPDRS-II\u2013walking: score of item 4\u2013walking of the UPDRS-II in the OFF medication.47.OFF\u2013UPDRS-III: total score of the UPDRS-III in the OFF medication.48.OFF\u2013UPDRS-III\u2013Rigidity: score of item 5\u2013rigidity of UPDRS-III in the OFF medication.49.OFF\u2013UPDRS-III\u2013Gait: score of item 12\u2013rigidity of UPDRS-III in the OFF medication.50.OFF\u2013PIGD or TD: Postural Instability/Gait Difficulty (PIGD) or Tremor Dominant (TD) phenotypes in the OFF medication, according to 51.OFF\u2013UPDRS-III asymmetry: clinical asymmetry was defined as the difference between the summed UPDRS scores of the left and right body sides (items 3.3\u20133.8 and 3.15\u20133.17). The most affected body side was the side with the highest UPDRS score in the OFF medication.52.OFF\u2013Stroop-I time (s): time to complete part I of the Stroop test in the OFF medication.53.OFF\u2013Stroop-I error: number of errors presented in part I of the Stroop test in the OFF medication.54.OFF\u2013Stroop-II time (s): time to complete part II of the Stroop test in the OFF medication.55.OFF\u2013Stroop-II error: number of errors presented in part II of the Stroop test in the OFF medication.56.OFF\u2013Stroop-III time (s): time to complete part III of the Stroop test in the OFF medication.57.OFF\u2013Stroop-III error: number of errors presented in part III of the Stroop test in the OFF medication.58.OFF\u2013TMTA time (s): time to complete part A of the TMT in the OFF medication.59.OFF\u2013TMTA error: number of errors presented in part A of the TMT in the OFF medication.60.OFF\u2013TMTB time (s): time to complete part B of the TMT in the OFF medication.61.OFF\u2013TMTB error: number of errors presented in part B of the TMT in the OFF medication.The C3Dfiles folder contains a folder for each participant and medication condition. For each participant, the following files are available for each trial separately:1.c3d files : The c3d files can store both the 3D coordinates of the markers and the force signals in the same file. In addition, the static trial , which contains only marker trajectories, is available;2.Visual 3D pipeline file (Parkinson.v3s) to enable users to process the data in the Visual 3D software;3.Model templates file (Parkinson.mdh) that contains the definitions of all landmarks, segments, and segment properties;4.Angular kinematics of all frames of the joints of the full body on the right and left side;5.Linear Kinematics of all frames of the coordinates of the markers and center of mass (CoM);6.GRF of all frames on the right and left side in the anteroposterior, vertical and mediolateral directions;7.For each gait cycle, spatiotemporal parameters, such as stride and step length and duration, and cadence.The gait cycles folder provides the average ensemble data for each participant and medication throughout the full gait cycle of the following data:1.CoM: center of mass of the body;2.Files named with ending Ang: angular kinematics of the joints of the full body on the right and left side. Each gait cycle is organized into three columns:a.Elbow: flexion/extension, add/abduction, and pron/supination;b.Shoulder: flexion/extension, add/abduction, and int/external rotation;c.Trunk: lateral flexion, rotation, and flexion/extension;d.Pelvis: tilt, obliquity, and rotation;e.Hip: flexion/extension, add/abduction, and int/external rotation;f.Knee: flexion/extension, add/abduction, and int/external rotation;g.Ankle: dorsi/plantarflexion, inv/eversion, and add/abduction;h.Foot: dorsi/plantarflexion, inv/eversion, and int/external rotation.3.Files named with ending grf contain three tabs (1) mean and (2) standard deviation of all gait cycles of the GRF on the right and left side in the anteroposterior, vertical, and mediolateral directions;4.Files named with ending kinematics contain three tabs (1) mean and standard deviation of the spatiotemporal parameters; (2) mean of all gait cycles of the angular and linear kinematics on the right and left side; and (3) standard deviation of all gait cycles of the angular and linear kinematics on the right and left side.The following is a partial exploratory analysis of the data. The curves in this section represent the ensemble average across all participants, only the right leg and the pelvis curves. DOI:10.6084/m9.figshare.14896881). The study contains raw data comprising marker trajectories and GRFs and processed data comprising joint angles that characterize the gait pattern of each participant. A limitation is that there was no foot contact with the force plate in some trials. This circumstance limits the usability of the force plate data. Our sample is small and heterogeneous. Future collections may complement our data set.This study presents a public data set of overground walking kinematics and kinetics in ON and OFF medication for 26 individuals with PD , which may help with PD diagnosis, symptom monitoring, therapy management, rehabilitation, and fall risk assessment and prevention. In addition, improving Parkinson\u2019s disease individuals\u2019 conditions is a major challenge that can be addressed with new emerging technologies such as collaborative robots to assist them during rehabilitation treatments or wearable sensors and devices to monitor and alert them to fall-risk situations; machine learning techniques can increase the effectiveness of these assistive and signaling devices by giving them some awareness of the patients\u2019 situations.10.6084/m9.figshare.14896881.The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: The studies involving human participants were reviewed and approved by Federal University of ABC. The patients/participants provided their written informed consent to participate in this study.TS: methodology, data curation, and writing\u2014original draft. TC, CO, RC, SH, EL, CB, and LS: methodology and data curation. MJ: writing\u2014review and editing and supervision. DC: conceptualization, methodology, formal analysis, writing\u2014review and editing, supervision, and project administration. All authors contributed to the article and approved the submitted version."} +{"text": "ACLF has a high risk of short-term mortality. ADAMTS13:AC and VWF:Ag are associated with ACLF development. We investigated the relationship between VWF:Ag/ADAMTS13:AC and prognosis of ACLF. In total, 101 patients with cirrhosis were enrolled in this study. The VWF:Ag/ADAMTS13:AC was associated with prognosis in the patients with ACLF in multivariate analysis. The cumulative survival of the patients with ACLF was significantly lower for patients with high VWF:Ag/ADAMTS13:AC compared with those with low VWF:Ag/ADAMTS13:AC. The VWF:Ag/ADAMTS13:AC predicted prognosis in patients with cirrhosis with ACLF.p < 0.05). The VWF:Ag/ADAMTS13:AC increased according to the progression of ACLF in patients with cirrhosis and predicted prognosis in patients with cirrhosis with ACLF.Acute-on-chronic liver failure (ACLF) has a high risk of short-term mortality. A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) is a metalloproteinase that specifically cleaves multimeric von Willebrand factor (VWF). Imbalance between ADAMTS13 and VWF is associated with portal hypertension, which induces ACLF development. A previous study reported that ADAMTS13 activity (ADAMTS13:AC) and VWF antigen (VWF:Ag) are predictive biomarkers of ACLF development in patients with cirrhosis. This study investigated the changes in ADAMTS13:AC and VWF:Ag levels from before to after the development of ACLF to determine their usefulness as a prognostic biomarker in patients with ACLF. In total, 101 patients with cirrhosis were enrolled in this study. The level of ADAMTS13:AC and VWF:Ag was determined by an enzyme-linked immunosorbent assay. Cox proportional hazard regression analysis was conducted to determine independent prognostic factors for patients with liver cirrhosis in the post-ACLF group. ADAMTS13:AC levels gradually decreased in the order of non-ACLF group, pre-ACLF group, and finally post-ACLF group. VWF:Ag and the ratio of VWF:Ag to ADAMTS13:AC (VWF:Ag/ADAMTS13:AC) levels gradually increased in the order of non-ACLF group, pre-ACLF group, followed by post-ACLF group. VWF:Ag/ADAMTS13:AC and CLIF-C ACLF scores were associated with prognosis in the post-ACLF group in multivariate analysis. The cumulative survival of the post-ACLF group was significantly lower for patients with high VWF:Ag/ADAMTS13:AC (>9) compared with those with low VWF:Ag/ADAMTS13:AC (\u22649) (HR: 10.72, 95% confidence interval: 1.39\u201382.78, A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13 (ADAMTS13) is a metalloproteinase that specifically cleaves multimeric von Willebrand factor (VWF) between the Tyr1605 and Met1606 residues in the A2 domain . ADAMTS1Acute-on-chronic liver failure (ACLF) develops in patients with LC after a bacterial infection, gastrointestinal bleeding, alcohol intake, or worsening of the underlying liver disease ,17. ACLFThis study investigated the changes in the imbalance of the ADAMTS13 enzyme\u2013VWF substrate from before to after the development of ACLF, to determine whether ADAMTS13:AC and VWF:Ag can be used as a prognostic biomarker in patients with ACLF.This retrospective observational study included a series of 101 patients with LC whose ADAMTS13:AC and VWF:Ag levels were assayed in our hospital between August 2012 and October 2021 . Among tg at 4 \u00b0C for 15 min and stored in aliquots at \u221280 \u00b0C until analysis. Plasma ADAMTS13:AC was determined via the sensitive chromogenic enzyme-linked immunosorbent assay (ELISA) [The samples were stored in plastic tubes containing 0.38% sodium citrate. Platelet-poor plasma was prepared by centrifuging at 3000\u00d7 , Japan) . The nor, Japan) .https://www.r-project.org, last accessed on 10 January 2023). EZR is a modified version of the R commander version 2.7\u20131 that includes statistical functions frequently used in biostatistics [p-value of <0.05 was considered significant.The statistical analysis was performed using EZR , which is a graphical user interface for R (p < 0.05) (p < 0.05) a. The VW < 0.05) b. Finall < 0.05) c.r = 0.492, p < 0.05), PT , and platelet count and Cre and PT and Cre (ADAMTS13:AC was directly correlated with Alb ( < 0.05) a\u2013c. In t < 0.05) d,e. VWF: < 0.05) f,g. Conv < 0.05) h,i.p < 0.05). The PT and ADAMTS13:AC levels in the survival subgroup of the post-ACLF group were higher than those of the mortality subgroup (p < 0.05 for both). The chronic liver failure consortium (CLIF-C) ACLF score, MELD score, VWF:Ag level, and VWF:Ag/ADAMTS13:AC level in the survival subgroup of the post-ACLF group were lower than those of the mortality subgroup . We performed univariate analysis using the factors that were reported previously for the association of prognosis of ACLF. To determine prognostic factors for patients with liver cirrhosis in the post-ACLF group, we performed multivariate analysis using VWF:Ag/ADAMTS13:AC, CLIF-C ACLF score, Cre, and MELD score, which had p-values <0.1 in the univariate analysis. The VWF:Ag/ADAMTS13:AC and CLIF-C ACLF scores were associated with prognosis in the post-ACLF group (p < 0.05 for both) (p < 0.05).The characteristics of the outcomes in patients with LC in the post-ACLF group are shown in or both) . The timor both) a. The AUor both) b\u2013d. The or both) e\u2013g. The In this study, ADAMTS13:AC, VWF:Ag, and VWF:Ag/ADAMTS13:AC levels gradually decreased, increased, and increased, respectively, in the order of the non-ACLF group, pre-ACLF group, and post-ACLF group. Our previous study reported that the VWF:Ag/ADAMTS13:AC became a predictive biomarker for ACLF development ,30, esopThe VWF:Ag/ADAMTS13:AC was demonstrated to be a prognostic biomarker for patients with LC with ACLF in the present study. A previous study reported that ACLF patients with high VWF:Ag levels had a lower survival rate than those with low levels . In addiPatients with LC have gut dysbiosis , which iThis study had several limitations, including enrolment at a single study center and a small sample size. Moreover, the occasional occurrence of VTE in patients with LC may affect the VWF:Ag/ADAMTS13:AC ,40. A prIn summary, the VWF:Ag/ADAMTS13:AC was increased according to progression of ACLF and was independently associated with prognosis in patients with ACLF."} +{"text": "Corrigendum to: Cranial Musculoskeletal Description of Black-Throated Finch (Aves: Passeriformes: Estrildidae) with DiceCTIntegrative Organismal Biology, Volume 3, Issue 1, 2021, obab007, https://doi.org/10.1093/iob/obab007Materials and methods, this should read: \u201cfledgling P. cincta ISIS No. 18031).\u201d instead of: \u201cfledgling P. cincta ISIS No. 18032).\u201d This error has now been corrected in the article online.In the originally published version of this manuscript, there was an error in a finch specimen number. In section In addition, the display of the Vietnamese abstract has been corrected in the PDF version of the manuscript."} +{"text": "PC provision is a moral obligation for all health professionals to protect public safety and wellbeing amid serious illness diagnosis and the heightened risk of suicide. Indeed, it is a matter of life and death.WER: Conceptualization, Writing\u2014Original Draft, Writing\u2014Review & Editing; MM: Writing\u2014Review & Editing; HMC: Writing\u2014Review & Editing.10.13039/100015348Cambia Health Foundation, 10.13039/100000867Robert Wood Johnson Foundation, and 10.13039/100017234The Rita and Alex Hillman Foundation. MM is funded by 10.13039/100000054NCI/10.13039/100000002NIH award number T32CA00946. WER and MM acknowledge 10.13039/100000054NCI/10.13039/100000002NIH award number P30CA008748. Unrelated to this manuscript, HMC has received grant funding from 10.13039/100008794Research Manitoba, 10.13039/100009395CancerCare Manitoba Foundation, 10.13039/501100000024Canadian Institutes of Health Research; receives book royalties from Oxford University Press; has received payment or honoraria from the Societa Italian\u00e1 Di Cure Palliative National and Saskatoon Hospice and Palliative Care Association; and serves on the ReSet Pharma/NYU advisory board for psilocybin protocol development in advanced cancer.WER has received funding unrelated to this manuscript from"} +{"text": "Bioscience Reports at the request of the authors due to concerns over the reliability of the results. The Editorial Office and the authors were alerted by a reader to apparent similarities between images in this manuscript with those from other manuscripts (from unrelated authors), which include the following:Figure 5C GAPDH/A549 bands and the GAPDH bands of both Fig. 5F from Liu et al. 2020 (doi: 10.1042/BSR20191330) and Fig. 4L from Fu et al. 2019 (doi: 10.18632/aging.102325),The Figure 3 A549 migration/si-NC, H1299 migration/si-circVANGL1 and the H1299 invasion/si-circVANGL1 panels with those from Figs. 6D and 7F from Yang et al. 2020 (doi.org/10.3389/fonc.2020.01104),Figure 2A (A549 and H1299/Bcl-2 and GAPDH bands) with bands from Fig. 3D from Sun et al. 2017 (doi: 10.18632/oncotarget.15846),The Figure 6A A549/GAPDH band with bands in both Fig. 3F from Chen et al. 2019 (doi: 10.1042/BSR20191050) and Fig. 4C from Li et al. 2019 (doi: 10.1042/BSR20181882).This article is being retracted from The authors have been unable to find the original data and are therefore unable to correct the article. They wish to retract the article. The Editor-in-Chief and Editorial Board agree with the retraction."} +{"text": "Proc. R. Soc. B288, 20210525. (Published online 23 June 2021). (https://doi.org/10.1098/rspb.2021.0525)Tetraselmis suecica growth rate. We hereby make the following three corrections in the Results, figure 1a and electronic supplementary material, table S1.We apologize for any inconvenience regarding the presentation of results on the Correction 1:Tetraselmis suecica (a). t-test pairwise comparisons show a significant difference of the red ALAN treatment from the dark .The first paragraph of the Results should read: The ALAN treatment did not have an effect on the growth rate of = 0.119) a. t-testCorrection 2:a) in Correction of panel (Correction 3: Correction of growth rate in electronic supplementary material, table S1."} +{"text": "Bioscience Reports at the request of the authors due to concerns over the reliability of the results. The Editorial Office and the authors were alerted by a reader to apparent similarities between images in this manuscript with those from other manuscripts (from unrelated authors), which include the following:Figure 5C GAPDH/A549 bands and the GAPDH bands of both Fig. 5F from Liu et al. 2020 (doi: 10.1042/BSR20191330) and Fig. 4L from Fu et al. 2019 (doi: 10.18632/aging.102325),The Figure 3 A549 migration/si-NC, H1299 migration/si-circVANGL1 and the H1299 invasion/si-circVANGL1 panels with those from Figs. 6D and 7F from Yang et al. 2020 (doi.org/10.3389/fonc.2020.01104),Figure 2A (A549 and H1299/Bcl-2 and GAPDH bands) with bands from Fig. 3D from Sun et al. 2017 (doi: 10.18632/oncotarget.15846),The Figure 6A A549/GAPDH band with bands in both Fig. 3F from Chen et al. 2019 (doi: 10.1042/BSR20191050) and Fig. 4C from Li et al. 2019 (doi: 10.1042/BSR20181882).This article is being retracted from The authors have been unable to find the original data and are therefore unable to correct the article. They wish to retract the article. The Editor-in-Chief and Editorial Board agree with the retraction."} +{"text": "The fourteenth author\u2019s name is spelled incorrectly. The correct name is: Iyad A. Yousef. There is also an error in affiliation 10 for author Iyad A. Yousef. The correct affiliation 10 is: Department of Physical Education, College of Education, Birzeit University, Ramallah, Palestine."} +{"text": "In \u201cThe Need for Standards Unification in Forensic Laboratory Practices: Protocol for Setting Up the Arab Forensic Laboratories Accreditation Center\u201d :e36778) the authors noted one error.In the originally published article, Reference 6 was incorrectly published as follows:Naglaa F. The Prevalence of Illicit Drugs and Alcohol in Road Traffic Accident Fatalities in the Eastern Region of Saudi Arabia. IJFMT 2020 Oct 7 [doi: 10.37506/ijfmt.v14i4.12122]This reference is now corrected as follows:Mahmoud NF, Al-Mazroua MK, Afify MM. The Prevalence of Illicit Drugs and Alcohol in Road Traffic Accident Fatalities in the Eastern Region of Saudi Arabia. Indian Journal of Forensic Medicine & Toxicology 2020;14(4): 3219-3225. [doi: 10.37506/ijfmt.v14i4.12122]The correction will appear in the online version of the paper on the JMIR Publications website on July 14, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."} +{"text": "Nature Communications 10.1038/s41467-022-31529-4, published online 01 July 2022Correction to: Nat. Commun.8, 1\u20136 (2017). The correct form of Ref. 18 is: Nat. Commun.8, 14540 (2017).The original version of this Article contained an error in Ref. 18, which was incorrectly given with the wrong page number as: Nat. Commun.7, 1\u20136 (2016). The correct form of Ref. 22 is: Nat. Commun.7, 10983 (2016).The original version of this Article contained an error in Ref. 22, which was incorrectly given with the wrong page number as: Light Sci. Appl.7, 1\u20136 (2018). The correct form of Ref. 33 is: Light Sci. Appl.7, 74 (2018).The original version of this Article contained an error in Ref. 33, which was incorrectly given with the wrong page number as: Nat. Commun.11, 1\u20137 (2020). The correct form of Ref. 40 is: Nat. Commun.11, 897 (2020).The original version of this Article contained an error in Ref. 40, which was incorrectly given with the wrong page number as: This has been corrected in the PDF version of the Article."} +{"text": "Laparoscopic vs. Open Pancreaticoduodenectomy After Learning Curve: A Systematic Review and Meta-Analysis of Single-Center StudiesBy Feng Q, Xin Z, Qiu J and Xu M (2021). Front. Surg. 8:715083. doi: 10.3389/fsurg.2021.715083The journal and Chief Editors retract the 10 September 2021 article cited above.Following publication, the cited article was found to be substantially similar to a previously published study by Feng et al. in Gland Surgery :1655\u20131668; doi: 10.21037/gs-20-916). Our investigation, conducted in accordance with Frontiers\u2019 policies, concluded that this similarity was unacceptably high, and the Publisher is retracting the article.\u201cThis retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers. The authors have agreed to the retraction.\u201d"} +{"text": "Erratum to: Hack B, Timalsina U, Tefera E, et al. Oral Prescription Opioids as a High-RiskIndicator for Hepatitis C Infection: Another Step Toward HCV Elimination. Journal of PrimaryCare & Community Health. January 2021. doi:10.1177/21501327211034379Incorrect versions of Figures 1 and 2 for this article were uploaded at the time ofpublication. The correct Figures are now published."} +{"text": "Int J Epidemiol 2020; doi: https://doi.org/10.1093/ije/dyaa226First published online: 8 December 2020, In the text of the results, several negative values in confidence intervals were published as positive values, and a hyphen was missing from a range of years indicating 2011 to 2016.These errors have now been corrected."} +{"text": "MYC/BCL2/BCL6 triple hit and TP53 deletion in a case of high-grade B cell lymphoma receiving CAR T cell immunotherapy. J Immunother Cancer 2021;9:e002029. doi:10.1136/jitc-2020-002029Wang J, Shang Z, Wang J, In the original published article, the funding statement was incomplete. The \u201c(No. 8170211 to MX)\u201d lost a number.The correct funding statement is: This work was supported by the National Natural Science Foundation of China (No. 81\u2009770\u2009211 to MX) and the National Natural Science Foundation of China (No.81830008 to JZ)."} +{"text": "CLINICS (Sao Paulo). 2021;76:e2914errhttps://doi.org/10.6061/clinics/2021/e2914, published in 2021.Erratum for: doi: Expression of Amphiregulin in Enchondromas and Central Chondrosarcomas, RESULTS section in the Abstract, remove the following sentences:In the article \u201cEnchondromas or chondrosarcomas? Please clarify. This will help understand the next sentence on enchondromas localized in short bones and long bones.\u201d"} +{"text": "Nymphalidae is the largest group of butterflies with high species richeness. Rhinopalpapolynice , a forest species, was discovered in the mid-stream of the Yuanjiang-Red River Valley of Yunnan Province for the first time, which represents the first record of the genus Rhinopalpa in China.The family R. polynice is the first record of the genus Rhinopalpa from China. The specimen was collected in the mid-stream of the Yuanjiang-Red River Valley of Yunnan Province. The female genitalia are described for the first time.The species Nymphalidae is a cosmopolitan family of Papilionoidea with high species richness, which includes about 6,100 species in 12 subfamilies and 350 genera and Dendrocnide (Urticaceae) in the wild , which i [1779]) . Rhinopa birmana . Rhinopathe wild . Three sthe wild . HoweverR. polynice was collected from Yuanyang County, southeast Yunnan, China, which sits in the mid-stream of the Yuanjiang-Red River Valley and is isolated from the sites in North Vietnam where R. polynice was previously recorded. The female genitalia are described for the first time. The specimen, collected in this study, is the first record of the genus Rhinopalpa in China. Both specimen and dissected genitalia are deposited in the insect collection of Southwest Forestry University (SFU), Kunming, China.In this study, a female Spread specimens were photographed by Canon 5DS with medium grey background and the photos were adjusted using Adobe Photoshop CS .To observe the female genitalia, the abdomen was treated with 1 ml 10% sodium hydroxide solution to digest soft tissue at 70\u2103 for 1 h and then dissected in a water-filled Petri dish under a stereoscope. The genitalia were then transferred to 80% glycerol for 12 h to render them transparent. A solutiion of 2% chlorazol black was used to dye the membranous parts for 10 min in order to obtain better photographic results. Photographs were taken with a Nikon SMZ1500 stereoscope and automatically stacked using Helicon Focus 7.5.8 . After observation and photography, a piece of card was cut, the genitalia were fixed to the card by white emulsion and pinned with the specimen to avoid confusion. The photographs were adjusted and arranged using Adobe Photoshop CS . Terminology of the female genitalia follows E0B18FEA-C7E3-5D41-B44C-DA0C61E125FDType status:Other material. Occurrence: recordedBy: Wen Shi; individualCount: 1; sex: female; lifeStage: adult; disposition: in collection; Taxon: scientificName: Rhinopalpapolynice ; kingdom: Animalia; phylum: Arthropoda; class: Insecta; order: Lepidoptera; family: Nymphalidae; genus: Rhinopalpa; specificEpithet: polynice; taxonRank: species; scientificNameAuthorship: ; vernacularName: The Wizard; taxonomicStatus: accepted; Location: country: China; stateProvince: Yunnan Province; county: Yuanyang County; locality: Shalatuo Village; verbatimElevation: 928m; verbatimCoordinates: 23\u00b06.047'N, 102\u00b034.43'E; Identification: identifiedBy: Huihong Zhang; dateIdentified: 2020; Event: samplingProtocol: sweep net; year: 2020; month: 9; day: 29; habitat: Evergreen broad-leaved forest; Record Level: basisOfRecord: PreservedSpecimenFemale daiyuanae Hu, Zhang & Cotton, 2018, Graphium wenlingae Hu, Cotton & Monastyrskii, 2019 and Losariadoubledayi , all of them being forest species in South Thailand to Malay Peninsula and ssp. birmana in Assam, Myanmar and Indochina (Rhinopalpap.birmana is different from R. p.eudoxia by paler colour on the upperside, plus better-defined hindwing subterminal black spot in space M1 and narrower forewing subterminal band (R. p.birmana. However, R. p.eudoxia, due to insufficient morphological differences. In this study, as we only examined one specimen, it is impossible to further analyse its subspecies status with such limited material. Hence, the subspecies identity of R. polynice in Yunnan still requires future study.In recent years, three cryptic species of butterflies were discovered from Indochina, species . Hence i forests , two subndochina . Rhinopanal band . Monasty"} +{"text": "International Journal of ObesityCorrection to: 10.1038/ijo.2016.206The original version of this article unfortunately contained a mistake in Table"} +{"text": "European Journal of Public Health, 2021, https://doi.org/10.1093/eurpub/ckab182In the originally version of the article, Figure 1 was published:but is now revised as follows:"} +{"text": "Vol 45 (08) 2015 | DOI: 10.1002/eji.201545451The presence of prolines in the flanking region of an immunodominant HIV\u20102 gag epitope influences the quality and quantity of the epitope generatedSabelle Jallow, Aleksandra Leligdowicz, Holger B. Kramer, Clayton Onyango, Matthew Cotten, Cynthia Wright, Hilton C. Whittle, Andrew McMichael, Tao Dong, Benedikt M. Kessler and Sarah L. Rowland\u2010JonesThe copyright line of the above article has been changed since first published on 24 June 2015 from the standard copyright to CC\u2010BY.The correct copyright of this article is:European Journal of Immunology published by Wiley\u2010VCH Verlag GmbH & Co. KGaA, Weinheim.\u00a9 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited."} +{"text": "R. Soc. Open Sci.7, 192151 (Published 5 August 2020) (doi:10.1098/rsos.192151)This correction refers to an error in the numeric values reported in This error has no implications on the results and conclusions drawn in the publication. The paper has now been updated."} +{"text": "There were errors in the extraction of numbers used to calculate the prevalence of limited health literacy, resulting in the incorrect extracted values for Souza, J. G., et al (2014), Kim, S. H. (2009), Chen, G. D., et al (2014), van der Heide, I., et al (2014), Aikens JE, Piette JD. (2009), Mancuso, J. M. (2010) and Wallace, A. S., et al (2010) in The Results section has also been affected by the errors in the extracted values. In the Included Studies subsection of the Results, there are errors in the second paragraph. The corrected paragraph should read: The study with the highest reported prevalence of limited health literacy (76.3%) was conducted to determine the mechanism through with health literacy exerted its influence on health outcomes related to diabetes care. It was a cross-sectional study involving 232 patients with T2DM attending regional hospital in Northern Taiwan. Health literacy was assessed using NVS. The mean age of the participants was 58.02 years (SD 9.49), 44.8% of participants were female, and 38.4% had received primary education or below. [55]The Pooled prevalence of limited HL: A meta-analysis subsection of the Results has also been affected and have been updated as a result. The corrected section should read: The pooled global prevalence of limited health literacy was 32.5% (95% CI: 24.9\u201340.1). Meta-analysis of all included studies yielded high heterogeneity ; which could primarily be explained by the country in which the study was conducted (p<0.001), the health literacy tool used (p = 0.002), participants\u2019 education levels (p<0.001), and the setting where the study was conducted (p<0.001). Most of the included studies (n = 18) were conducted in the USA. Thirteen of these studies measured functional HL specifically, these studies were included in a separate meta-analysis and presented in a forest plot in Figs"} +{"text": "Correction to: BMC Public Health 20, 1150 (2020)https://doi.org/10.1186/s12889-020-09258-4The authors of this study would li1). Reference 19 and 20 is reversed. The following description is correct.https://www.mhlw.go.jp/english/database/db-hw/vs01.html19. Ministry of Health, Labour and Welfare, Vital statistics in Japan 20. von Elm E, Altman DG, Egger M, Pocock SJ, Gtzsche PC. Vandenbroucke JP; STROBE initiative. Strengthening the reporting of observational studies in epidemiology (STROBE)statement: guidelines for reporting observational studies. BMJ. 2007;335:8068.2). In abstract, the descriptions do not match the results in the table 3 and 5. The following description is correct.Results: Numbers of target facilities changed yearly: 1857 in 2011, 2544 in 2013, and 2376 in 2016. The mean number of screening-test participants increased per facility, but the median increased or decreased. The mean number of positive individuals identified decreased. Multivariate analysis results revealed the number of screenings was reduced in Kanto and Chubu/Tokaiareas, although some areas (Hokkaido/Tohoku and Chugoku/Shikoku) and high volume in facility types increased. Regarding the positive rates, some areas exhibited decreases or increases by facility type. The number of western blotting (WB) implementations decreased in 2016, positive rates identified by WB decreased in 2016 andin all areas, and the number of facility types increased. The number of PCR participants increased in 2016 andin Kinki, but a decrease in facility type was observed. Positive rates were decreased in all areas (except Chubu/Tokaiarea) but facility types were increased.3) (P3) Results: the descriptions do not match the results in the table 3 and 5. The following description is correct.By multivariate analysis, some areas (Hokkaido/Tohoku and Chugoku/Shikoku) and facility types showed increased screening coverage although screening coverage in other areas (Kanto and Chubu) decreased. Positive rates were decreased in some areas and positive identification increased by facility type. Numbers of WB performed were decreased in 2016 and the positive identification rate was lower in 2016 and inall areas; however, facility types were increased. The number of PCR participants was markedly increased in 2016 and inKinki;"} +{"text": "Vol .14 (2021) No. 2 pp. 202\u20132302018 JAPAN Critical Limb Ischemia Database (JCLIMB) Annual ReportThe Japanese Society for Vascular Surgery JCLIMB CommitteeIn the above secondary publication article, numerical errors in tables were found after the publication. The erratum of the original Japanese article was published in Japanese Journal of Vascular Surgery Vol. 30 (2021) No. 4. The corrected version of table is given on the next page.Table 4-4p. 221, Incorrect:Correct:"} +{"text": "BMJ 2021;374:n2106, doi:10.1136/bmj.n2106, published 29 September 2021), two research team members were inadvertently missed in the article\u2019s submission. The article and PDF will be updated in due course.In this paper by Gray and colleagues ("} +{"text": "Correction to:Clin Trans Immunol 2019; 8: e1050. doi: https://doi.org/10.1002/cti2.1050. Published online 20 May 2019.The authors inadvertently excluded a funding body in the Acknowledgments section. The corrected version appears below:ACKNOWLEDGMENTSWe acknowledge support from the Cancer Council SA Beat Cancer Project Hospital Research Support Package, a Cancer Council Early Career Research Fellowship, the Health Services Charitable Gifts Board (Adelaide) and The Hospital Research Foundation.The authors apologise for this error."} +{"text": "Vol. 218, No. 4 | 10.1084/jem.20202187 | January 19, 2021The authors regret that the amino acid sequence of one of the T epitopes in The error appears in print and in PDFs downloaded before September 30, 2021."} +{"text": "J Am Heart Assoc. 2021;10:e019605. DOI: 10.1161/JAHA.120.019605), corrections were needed.In the article by Tarp et al, \u201cFitness, Fatness, and Mortality in Men and Women From the UK Biobank: Prospective Cohort Study,\u201d which published on March 13, 2021 and appeared in the March 16, 2021 issue of the Journal \u201d. No change has been made to the data in those rows.The publisher regrets the errors.https://www.ahajournals.org/doi/10.1161/JAHA.120.019605.The footnotes have been added to the current online version of the article, which is available here:"} +{"text": "In the original article published, the references are cited incorrectly in Tables 1, 2 and 3. The correct information is given below:The correct citation number for the study Plato et al. is reference number 39: Plato CC, Norris AH. Osteoarthritis of the hand: longitudinal studies. Am J Epidemiol. 1979;110(6):740\u2013746.The correct citation number for the study Kallman et al. is reference number 37: Kallman DA, et al. The longitudinal course of hand osteoarthritis in a male population. Arthritis Rheum. 1990;33(9):1323\u20131332.The correct citation number for the study Busby et al. is reference number 38: Busby J, et al. A longitudinal study of osteoarthritis of the hand: the effect of age. Ann Hum Biol. 1991;18(5):417\u2013424.The correct citation number for the study Kalichman et al. is reference number 43: Kalichman L, et al. Repeated measurement study of hand osteoarthritis in an apparently healthy Caucasian population. Am J Hum Biol. 2005;17(5):611\u2013621.The correct citation number for the study Kalichman et al. is reference number 44: Kalichman L, et al. Epiphyseal expansion in hand bones: association with age, sex, and hand osteoarthritis. Osteoarthr Cartil. 2008;16(5):560\u2013565.The correct citation number for the study Hoeven et al. is reference number 40: Hoeven TA, et al. Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study. Ann Rheum Dis. 2013;72(5):646\u2013651.The correct citation number for the study Haugen et al. is reference number 41: Haugen IK, et al. The prevalence, incidence, and progression of hand osteoarthritis in relation to body mass index, smoking, and alcohol consumption. J Rheumatol. 2017;44(9):1402\u20131409.The correct citation number for the study Marshall et al. is reference number 42: Marshall M, et al. Metabolic risk factors and the incidence and progression of radiographic hand osteoarthritis: a population-based cohort study. Scand J Rheumatol. 2019;48(1):52\u201363."} +{"text": "The above article from Food Science & Nutrition, published online on 05 June 2020 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the authors, the Editor\u2010in\u2010Chief, Martin Lo, and Wiley Periodicals LLC. The retraction has been agreed due to an error in Formula 2 which invalidates the results of the study.Retraction: Zhang X, Zhang J, Chen T. An ANP\u2010fuzzy evaluation model of food quality safety supervision based on China's data. Food Sci Nutr. 2020;8: 3157\u20133163."} +{"text": "Correction to: BMC Cancer 22, 203 (2022)https://doi.org/10.1186/s12885-022-09299-5Following publication of the original article , an erroDr. Yehoda Martei\u2019s research work is supported by an NIH K01 Award\u2014K01TW011481. Bege Dauda\u2019s research is supported by the Penn Center for Global Genomics and Health Equity (PennGGHE) with funding from Genentech, Inc. and the Penn Medicine Office of Inclusion, Diversity, and Equity.The original article has been"} +{"text": "These corrigenda serve to correct figure errors in the article by Ju et al:, the 40X image for the nontarget control (NTC) condition was a duplicate of the RhoB\u20102 micrograph.In Figure Figure 4 is, as follows:The correct version of Additionally, in Figure https://kmplot.com/) for RhoB using: Affymetrix id 212099_at, median cutoff, JetSet best probe set, and 120\u2009months as follow up threshold.All plots were made from data using the online data portal (The correct version of Figure Neither error alters the results or conclusions of the study. The authors regret any inconvenience this may have caused.Reference:Ju JA, Godet I, DiGiacomo JW, GilkesDM. RhoB is regulated by hypoxia and modulates metastasis inbreast cancer.Cancer Reports. 2020;3:e1164.https://doi.org/10.1002/cnr2.1164"} +{"text": "Correction on:Pregnant women\u2019s knowledge of non-pharmacological techniques for pain relief during childbirthBy Maria A. Heim, Maria Y. MakuchEuropean Journal of Midwifery, Volume 6, Issue February, Pages 1-6Publish date: 7 February 2022https://doi.org/10.18332/ejm/145235DOI: https://doi.org/10.18332/ejm/145235. The pdf file has been replaced.In the original article, in the pdf file of the manuscript, the article DOI number did not correspond to the assigned DOI number. The correct manuscript DOI is"} +{"text": "Journal of Experimental Botany, Advance Access publication: 18 June 2020, doi: doi:10.1093/jxb/eraa285The version of this article that first published contained an error in the unit scale in Fig. 1E. The correct value of 0.025 nm has now been included. The Publisher apologizes for this error."} +{"text": "International Journal of Oral Science 10.1038/s41368-020-00101-5, published online 14 December 2020Correction to: 1 the authors reported the below errors.Following publication of this article,1. Reason for modification: ambiguous descriptionThird section of RESULTS: Effects of autophagy on the degradation of FN1Lines 17\u201320, paragraph 4: The data showed that CQ strongly inhibited autophagic activity and blocked the degradation of FN1 in SCC-25 cells and SCC-15 cells until 18\u2009h.Baf A1 strongly blocked the degradation of FN1 in SCC-15 cells until 18\u2009h.Corrected to: The data showed that CQ strongly inhibited autophagic activity and blocked the degradation of FN1 in SCC-25 cells and DISCUSSION:The first sentence of paragraph 3: Vimentin has been excluded as a marker of metastasis in a variety of cancers, such as breast cancer and non-small cell lung carcinoma.regarded as a marker of metastasis in a variety of cancers, such as breast cancer and non-small cell lung carcinoma.Corrected to: Vimentin has been 2. Reason for modification: Misaligned with the content of FigureSecond section of RESULTS: Autophagic activity in different OSCC cell linesLine 14: .Corrected to: .Third section of RESULTS: Effects of autophagy on the degradation of FN1Line 1, paragraph 4: Fig. 4kCorrected to: Fig. 4aThe last section of RESULTS: Roles of the PB1 and UBA domains of p62 in the degradation of FN1The fourth line from the bottom: .Corrected to: .3. Reason for modification: Mistakes of figure legend serial number sequenceLegend of Fig. 2:c Western blot data. d Migration assay data. e Western blot data.Line 2: c Migration assay data. d Western blot data. e AO staining data. f Western blot data.Corrected to: Legend of Fig. 4:h Quantification of the average fluorescence values of single cells in Fig. 3g.Line 5: h Quantification of the average fluorescence values of single cells in (g).Corrected to: Fig. 5:b, c serial number error, b label content is incorrect.Original Figure 5:Corrected to: Switch the serial numbers b and c. IB: BN1 changed to IB: FN1.Revised Figure 5:"} +{"text": "Correction to: Trop Med Health 49, 48 (2021)https://doi.org/10.1186/s41182-021-00340-0Following publication of the original article , a fundibold typeface.The updated Funding section is given below and the changes have been highlighted in FundingThis study is partially funded by Japan Agency for Medical Research and Development, Grant/Award Numbers: JP19fk0108104h0401, JP20fk0108104h0402.This work is in part funded by Nagasaki University . The original article has been"} +{"text": "The divThe content from Equations (1) and (2) in Section 2 needs to be corrected. The updated information is included below:The cited reference [27] needs to be corrected. The updated information is included below:divIt should be noted that, in Equation (2), we take into account the incompressibility of the nanofluid: The content from Equations (3) and (4) in Section 2 needs to be corrected. The updated information is included below:The References section needs to be corrected. The book title in Ref. [26] was incorrect. The updated information is included below:Fluid Mechanics, 2nd ed.; Pergamon: London, UK, 1987.26. Landau, L.D.; Lifshitz, E.M. The changes do not affect the scientific results or conclusions in the original published paper.The authors would like to apologize for any inconvenience caused to the readers by these changes."} +{"text": "PLoS Computational Biology, volume 3, issue 2: doi:10.1371/journal.pcbi.0030025In The set of four equations in the Materials and Methods section had three extra minus signs, which were incorrect. The following are the correct equations."} +{"text": "PLoS Clinical Trials, volume 1, issue 2: DOI: 10.1371/journal.pctr.0010012In The numbering of the reference citations in Table 2 is incorrect. The correct numbering is shown in the table below."} +{"text": "PLoS Pathogens, volume 2, issue 6: DOI: DOI: 10.1371/journal.ppat.0020066In The PDF version of the above article states that a previous version was published as an Early Online Release on June 23, 2006. This information appeared in error. No previous version of the article has been published."} +{"text": "PLoS Medicine, volume 3, issue 8: doi:10.1371/journal.pmed.0030295In Equation 1 appeared incorrectly. It should read as:The equations in the legend of Table 1 were also incorrect. The full model should be:The null model should be:"} +{"text": "Thousand Oaks (CA): Sage Publications; 2003) was omitted from the list of references; and several of the references were not numbered consecutively. Corrections were made on our Web site on June 15, 2007, and appear online at www.cdc.gov/pcd/issues/2007/apr/06_0076.htm. We regret any confusion or inconvenience this error may have caused.Because of an editing error, the references in the article \"From Heart Health Promotion to Chronic Disease Prevention: Contributions of the Canadian Heart Health Initiative\" were incorrectly presented. References (4) and (14) were omitted from the text of the article; one source (Creswell JW. Research design: qualitative, quantitative, and mixed methods approaches. 2"} +{"text": "PLoS Computational Biology, vol 2, issue 12: doi:10.1371/journal.pcbi.0020156In In the Acknowledgments section of this Perspective, the spelling of the name of Pavel Pevzner was incorrect."} +{"text": "PLoS Medicine, volume 4, issue 4, doi:10.1371/journal.pmed.0040074:In PLoS Medicine article, the article in The Lancet was still in press):The author inadvertently omitted the following citation that addresses the same topic Global burden of childhood hearing impairment and disease control priorities for developing countries. Lancet 369: 1314\u20131317.Lancet paper, as reference [10], in an earlier Correspondence article published in PLoS Medicine: Olusanya BO (2007) \u201cThe Right Stuff\u201d: The Global Burden of Disease. PLoS Med 4(2): e84. doi:10.1371/journal.pmed.0040084The author did, however, cite this"} +{"text": "Correction to:Molecular Psychiatry advance online publication, 8 December 2015; doi:10.1038/mp.2015.178Following publication of this paper, the authors noticed that"} +{"text": "Ianiropsis serricaudis (first record for the Iberian Peninsula and Lusitanian marine province), Paracerceis sculpta (first record for the Alboran Sea ecoregion), Paradella dianae, Paranthura japonica (earliest record for the Iberian Peninsula) and Sphaeroma walkeri. Photographs with morphological details for identification for non-taxonomic experts are provided, their worldwide distribution is updated and patterns of invasion are discussed. We report an expansion in the distribution range of all species, especially at the Strait of Gibraltar and nearby areas. Ianiropsis serricaudis and Paranthura japonica are polyvectic, with shellfish trade and recreational boating being most probable vectors for their introduction and secondary spread. The subsequent finding of the studied species in additional marinas over the years points at recreational boating as a vector and indicates a future spread. We call for attention to reduce lags in the detection and reporting of small-size exotics, which usually remain overlooked or underestimated until the invasion process is at an advanced stage.Effective management of marine bioinvasions starts with prevention, communication among the scientific community and comprehensive updated data on the distribution ranges of exotic species. Despite being a hotspot for introduction due to numerous shipping routes converging at the Strait of Gibraltar, knowledge of marine exotics in the Iberian Peninsula is scarce, especially of abundant but small-sized and taxonomically challenging taxa such as the Order Isopoda. To fill this gap, we conducted several sampling surveys in 44 marinas and provide the first comprehensive study of marine exotic isopods from the Iberian Peninsula, the southern side of the Strait of Gibraltar (northern Africa) and the Balearic Islands. Exotic species included Carcinus maenas and the Chinese mitten crab Eriocheir sinensis , both being aggressive competitors for native species, affecting aquaculture facilities and harvests and causing structural damage to river banks , despite having a much smaller size and being less notorious, also achieved a globally widespread distribution in a relatively short timeframe, as well as causing malfunctioning to pumps and fouling biomass to cages in aquaculture facilities and from the IPTM (Instituto Portu\u00e1rio e dos Transportes Mar\u00edtimos: http://www.atlanticstrategy.eu/en/partners/iptm-instituto-portu%C3%A1rio-e-dos-transportes-mar%C3%ADtimos-ip). Census data for the locality to which each marina belongs was obtained from the National Statistical Systems of Spain (http://www.ine.es), Portugal (http://www.ine.pt) and Morocco (http://www.hcp.ma) . Voucher material of each species was deposited in the Museo Nacional de Ciencias Naturales , Madrid, Spain. The rest of the material was kept in the Laboratorio de Biolog\u00eda Marina, University of Seville, Spain.Examined material was collected during several sampling surveys carried out from 2011 to 2017, in order to study the fouling epifauna in 44 marinas around the Iberian Peninsula, the Southern side of the Strait of Gibraltar (northern Africa) and Baleares. Marina choice was based on its vessel traffic and popularity as tourist locality (see .hcp.ma) . In 2011ibraltar . AdditioIaniropsis serricaudis, Paracerceis sculpta, Paradella dianae, Paranthura japonica and Sphaeroma walkeri had increased the number of exotic species, sometimes by 200% or more record of Paranthura japonica from the Iberian Peninsula. We report an extension in the distribution range for all species along the coasts of the Iberian Peninsula and adjacent waters.Five exotic marine isopods were found on fouling communities associated to marinas: walkeri . From thmore see . We provJaniropsis serricaudisIaniropsis notoensisIaniropsis serricaudisIaniropsis sp. Ianiropsis sp. St3: 2 males (MNCN 20.04/11439), 18 males and 119 females clinging on bryozoan Bugula neritina, floating pontoons, 07/05/2011.Material examined : Ianiropsis is similar to Janira and Carpias: three claws on walking legs, coxae visible in dorsal view and usually can only be definitely identified from the males. Ianiropsis can be distinguished from the other two by bearing an elongated carpus of male pereopod I (Carpias) or not elongated propodus and carpus at all (Janira) (I. serricaudis: (i) antennal peduncle segments 6 and 7 particularly elongated relative to the overall length of the antennae . Our speantennae ; (ii) heantennae , 1C daantennae .Laminaria, in water temperatures from 1.8\u00a0\u00b0C to 24\u00a0\u00b0C , 01/07/2017. St13: Six males, 13 females and 24 juveniles from Corallinaceae algae and green algae, 13/05/2017. St14.1: Four females and one juvenile on B. neritina, one male and one juvenile on Eudendrium sp., and one male and two female on Coralline algae, floating pontoons, 14/05/2017; four males, 12 females and 33 juveniles from fouling community on floating pontoons, 14/05/2017; one male and two females (MNCN 20.04/11443), three males six females and 16 juveniles collected from fouling community on floating structures, 02/07/2017. St14.2 One female and one juvenile from fouling substrates, floating structures, 02/07/2017. St34: One juvenile on A. verticillata, floating pontoons, 27/06/2011. St37: One female and one juvenile on A. verticillata, floating pontoons, 26/06/2011. St43: One female on Eudendrium sp., floating pontoons, 09/2012.Material examined : Paranthura species. These are: eyes well developed composed of less than 17 dark ommatidia; anterolateral angles of cephalon exceeding rostral projection; antenna 1 with 8 distinct articles , among algae (Sargassum) and in mussel beds and oyster reefs , 14 males, 224 females and 192 juveniles on fouling substrates, floating structures , 26/06/2017. St10: one female and four juveniles on fouling substrates, floating structures, 26/06/2017. St12: one female on fouling substrates, floating structures, 01/07/2017. St13: Three juveniles on B. neritina, one female and 10 juveniles on A. verticillata, floating pontoons, 17/05/2011; six juveniles on Coralline algae and green algae, floating pontoons, 13/05/2017. St14.1: One male, nine females, 19 juveniles on B. neritina, one male, 29 females, 23 juveniles on A. verticillata, floating pontoons, 17/05/2011; one female and six juveniles on A. verticillata, 12/2011; one juvenile on A. verticillata, one male and one female on hydrozoan Eudendrium sp., 05/2012; one juvenile on A. verticillata, 06/2012; one juvenile on A. verticillata, 07/2012; one female and 23 juveniles on A. verticillata, 08/2012; 15 females and 39 juveniles on A. verticillata, 09/2012; one female and five juveniles on A. verticillata, 10/2012; two females and nine juveniles on A. verticillata 11/2012; 8 females and 155 juveniles on fouling community, floating pontoons, 14/05/2017. St14.2: One male, six females and six juveniles on fouling substrates, floating structures, 01/07/2017. St16: One juvenile on B. neritina, floating pontoons, 17/05/2011. 18 females and 139 juveniles on fouling substrates, floating pontoons, /06/2017. St17: One male, 18 females and nine juveniles on fouling substrates, floating structures, 01\u221507\u22152017. St18: One juvenile on B. neritina, floating pontoons, 15/05/2011. St19: Two males, 18 females and 26 juveniles on fouling substrates, floating structures, 29/06/2017. St28: three females and seven juveniles on B. neritina, floating pontoons, 29/06/2011. St29: 8 females and 10 juveniles on B. neritina, floating pontoons, 29/06/2011. St30: Two juveniles on A. verticillata, floating pontoons, 28/06/2011. St31: One female and three juveniles on B. neritina, three females and seven juveniles on A. verticillata, floating pontoons, 28/06/2011. St34: five juveniles on B. neritina, six females and 54 juveniles on A. verticillata, floating pontoons, 27/06/2011. St40: Two juveniles on B. neritina, floating pontoons, 29/95/2011. St41: Seven juveniles on B. neritina, floating pontoons, 30/05/2011. St42: Two females and four juveniles on B. neritina, one juvenile on A. verticillata, floating pontoons, 30/05/2011.Material examined : Paracerceis, together with other Cerceis-like genera, can be distinguished by bearing pronounced marginal teeth on exopods of pleopods 1\u20133, especially obvious on pleopod 2 , five females and 36 juveniles collected from Corallinaceae algae and green algae, floating pontoons, 13/05/2017. St14.1: Two juveniles collected from fouling community, floating pontoons, 14/05/2017. St17: One male collected from fouling community of floating structures 01/07/2017. St23: One female collected from fouling substrates, floating structures, 28/06/2017. St22: One female from fouling substrates, floating structures, 28\u221506\u22152017 and one female on Bugula neritina, floating pontoons, 03\u221507\u221511.Material examined : Dynamenella dianae), Paradella can best be identified by males having a distinct dorsally-directed, Y-shaped and posteriorly closed pleotelson foramen; long, tapering and basally fused penial processes, and a long and basally narrow appendix masculina that usually extends beyond the distal margin of the endopod collected from fouling community, floating structures , 02/07/2017.Material examined : Sphaeroma can be distinguished from related genera like Exosphaeroma and Lekanesphaera by bearing a robust maxilliped, particularly the palp, articles II\u2013IV without lobes and a fringe of robust, plumose setae on internal border of endite see in an esand) see . Also inl, 1923) or in ascilities .The first evidence of its occurrence in the Mediterranean Sea took place in 2012, when it was found to be abundant in the Lagoon of Venice . The Lagversus the reported from native regions (up to seven). Moreover, our specimens were considerably large in comparison to those reported from Russia from thefemales) and fromfemales) . Whetherve range .I. serricaudis is probably linked to accidental introduction with shellfish transfers. This is a likely associated vector (see Crassostrea gigas) and the Japanese clam (Ruditapes philippinarum), and export to other countries of Europe (ia (USA) and its ia (USA) , San Quiia (USA) ; Puerto ia (USA) and nortia (USA) . It has ia (USA) ; and at ia (USA) . It was ia (USA) . From thia (USA) , Hong Koia (USA) , Taiwan ia (USA) and Japaia (USA) , to Austia (USA) and nortia (USA) . It is aia (USA) . In the ia (USA) , and decia (USA) and westia (USA) . In the ia (USA) . In the ia (USA) , collectia (USA) , collectParacerceis sculpta , being sP. dianae arrived to the Iberian Peninsula and the Mediterranean Sea from the Indian Ocean, from the Atlantic Ocean, or from both through multiple introductions. It was reported from the Italian coast in 1980 or the Madeira island system itself since the early 1980s . Its native range only includes localities from Japanaese coasts (Crassostrea gigas (Thunberg 1793) from the Senday Bay (Japan) was massively introduced (Crassostrea angulata (Lamarck 1819). Paranthura japonica probably remained unnoticed or misidentified since then (see Ruditapes philippinarum (Adams and Reeve 1850) during the 1970s; and secondary spread to further Mediterranean marinas at least since 2011. P. japonica was found in Barcelona, Benicarl\u00f3 and Mallorca , which are popular destinations for vessels cruising the western Mediterranean in between Barcelona to the West and northwestern Italy to the East . In 2014, two individuals of P. japonica were found within the Strait of Gibraltar\u2019s vicinity, in Chipiona rocky shores (C\u00e1diz) ; and three years later, it was abundant in marinas located in C\u00e1diz Bay. C\u00e1diz is a great hotspot for both international commercial shipping and pleasure craft, as well as a center for aquaculture production, including the Japanese clam Ruditapes philippinarum , and later on to C\u00e1diz marinas (present in 2017). It is to be noticed that P. japonica was not present in the bryozoan B. neritina in Puerto Am\u00e9rica marina in 2011; but it was found associated to the same host in 2017. This fact supports this record as a new arrival of NIS into a particular region, and thus represents a Marine Strategy Framework Directive indicator to establish C\u00e1diz Bay as a hotspot for marine introductions, following It was reported only recently from the Iberian Peninsula, from samples collected from fouling assemblages in marinas of the eastern coast in 2016 . Neverthppinarum . Just asi.e. role as prey-predator in the trophic chain, habitat selection, role in their ecosystem functioning) are of great need in here (see We have reported a distribution range extension for all exotic isopod species present in the studied areas, some of them proving to be polyvectic and well established in marinas. The next step is to evaluate their potential biological, social and economical impact, however, there are gaps of knowledge that hamper this task. Baseline studies delving into the ecology of all these species (here see . AlthougThere is a critical problem that keeps recurring and needs to be reduced: the lags in detection of a new arrival. In many occasions, much time lapse between the initial introduction and the report of it, with a bias for noticing invaders only after they become an abundant nuisance, due to inadequate monitoring or lack of taxonomic expertise see . This haIn order to be ready for decision making and implementation of invasion control, as well as assessment of future arrivals, prevention is the key; and all this starts with building comprehensive data on the presence and distribution range of exotic species, especially on new arrivals see . We cons10.7717/peerj.4408/supp-1Table S1List of introduced isopod species in European waters, updated with the findings of the present study. Name of the species, parasite/free-living status, origin, distribution in European waters, introduction status remarks and likely vectors of introduction are provided. MED, Mediterranean Sea; WMED, Western Mediterranean; CMED, Central Mediterranean; EMED, Eastern Mediterranean; ATL, Atlantic; NOR, North Sea; C, casual; E, established; NE, non-established; nd, no data available. Species with asterisk are those found to be present in the Iberian Peninsula.Click here for additional data file."} +{"text": "Correction to:Translational Psychiatry (2016) 6, e909; doi:10.1038/tp.2016.179; published online 4 October 2016In the online version of this paper, the second chart that appears in the Materials and Methods section, 'Real-time PCR' subsection, is incorrect. The correct chart appears below:The publisher regrets this error."} +{"text": "Correction to:Molecular Psychiatry (2017) 22: 1502-1508; advance online publication, 12 July 2017; doi: 10.1038/mp.2016.97In the first paragraph of the Results section and The corrected figure appears in previous page."} +{"text": "Correction to:Human Genome Variation (2016), 3, doi: 10.1038/hgv.2016.20; advance onlinepublication 7 July 2016After the online publication of this article, the authors noticed an error in the figureand legend of The correct figure should show that leftmost SNP is rs7939918.The correct The authors apologize for any inconvenience caused."} +{"text": "Current collection continues the series of BioMed Central special post-conference issues presenting the highlights from the set of meetings on bioinformatics and systems biology held in Novosibirsk and Moscow, Russia in 2017.http://conf.bionet.nsc.ru/belyaev100/en). This Memorial Conference included special session on medical aspects of the genomics. In 2017, \u201cVavilov Journal of Selection and Breeding\u201d published a series of memoirs publications about Prof. Belyaev (http://vavilov.elpub.ru/jour/issue/view/32/showToc).Year 2017 marks the 100-th anniversary since birth of Professor Dmitry K. Belyaev (1917\u20131985), Full Member of the USSR Academy of Sciences, world-famous visionary in evolution and genetics. In view of this memorable date, the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (ICG SB RAS) held international Belyaev Conference on Genetics and \u201cHigh throughput sequencing in genomics\u201d (NGS-2017) conferences in Novosibirsk (http://conf.nsc.ru/HSG2017/ru/hsg2017_hsg_thesis). Modern technologies in medicine more and more become interconnected with advances in sequencing in fundamental evolutionary studies. Previously published special issues of BMC Evolutionary Biology and BMC Genomics covered the proceedings of BGRS\\SB-2016 conference and SBB-2015 School in Novosibirsk [https://bmcgenomics.biomedcentral.com/articles/supplements/volume-15-supplement-12). The materials on evolutionary biology and genetics were recently published in BMC Evol Biol and BMC Genetics Supplements , correspondingly [Thematic issue of osibirsk as well This issue collected works on sequencing, genotyping, computational analysis and gene network reconstruction in human diseases.Anastasiya Snezhkina et al. describeThe work by Maxim Ivanov and colleagues discusseYu-Feng Huang et al. continueUlyana Boyarskikh and colleagues present Olga Saik et al. showed tGalatenko and colleagues identifiAbeer Fadda et al. discuss ASPM gene. The work represents an additional support for the clinical continuum between Seckel Syndrome and primary microcephaly.Andrey Marakhonov et al. describeBMC Evolutionary Biology , BMC Plant Biology , BMC Genetics \u00a0(published at the end of 2017), BMC Genomics , BMC Structural Biology and BMC Neuroscience . The Proceedings of the conference are available at http://conf.bionet.nsc.ru/belyaev100/enhttp://conf.bionet.nsc.ru/belyaev100/wp-content/uploads/sites/14/2017/01/BELYAEV_conf_2_08_2017.pdf.Follow-on series of related works in the areas of genomics, genetics, and plant biology discussed at \u201cBelyaev conference \u2013 2017\u201d and other related meetings in Novosibirsk are published in the Special Issues of http://conf.bionet.nsc.ru/bgrssb2018/en).The readers are welcome to visit Novosibirsk at the time of next XI-th BGRS\\SB-2018 conference on August 20-28th in 2018 ("} +{"text": "In the Funding section, a grant number from the funder National Science Centre, NCN Poland, UMO is listed incorrectly. The correct grant number is: 2015/17/D/NZ8/00782. The correct Funding statement is: This work was supported by the National Science Centre, NCN Poland, UMO-2016/21/B/NZ8/01542 to EG and 2015/17/D/NZ8/00782. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."} +{"text": "International Journal of Environmental Research and Public Health [http://www.mdpi.com/1660-4601/11/9/9897.The authors wish to update the Acknowledgments Section in their paper published in the c Health , doi:10."} +{"text": "Rahman RA. It should be Abdel Rahman R. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.In the original article, the name of one of the authors was incorrectly spelled in the citation section as Citation: Aristei S, Zwitserlood P and Rahman RA (2012) Picture-induced semantic interference reflects lexical competition during object naming. Front. Psychology3:28. doi: 10.3389/fpsyg.2012.00028This article was submitted to Frontiers in Language Sciences, a specialty of Frontiers in Psychology.Copyright\u00a9 2012 Aristei, Zwitserlood and Rahman.Citation: Aristei S, Zwitserlood P and Abdel Rahman R (2012) Picture-induced semantic interference reflects lexical competition during object naming. Front. Psychology3:28. doi: 10.3389/fpsyg.2012.00028This article was submitted to Frontiers in Language Sciences, a specialty of Frontiers in Psychology.Copyright \u00a9 2012 Aristei, Zwitserlood and Abdel Rahman.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."} +{"text": "In the article titled \u201cPrenatal Diagnosis of Cardiac Diverticulum with Pericardial Effusion in the First Trimester of Pregnancy with Resolution after Early Pericardiocentesis\u201d , there wThe errors in the in-text citations of references in the Discussion should be corrected as follows:The original text: Ultrasonographic findings associated with diverticula include pericardial effusion, cardiomegaly, septal defects and arrhythmia with fetal death before delivery, and hydrops .The corrected text: Ultrasonographic findings associated with diverticula include pericardial effusion, cardiomegaly, septal defects and arrhythmia with fetal death before delivery, and hydrops .The original text: Thus, the observation of pericardial effusion makes it necessary to examine the cardiac function .The corrected text: Thus, the observation of pericardial effusion makes it necessary to examine the cardiac function .The original text: Five of them showed spontaneous resolution (71%) and 2 resulted in intrauterine death (29%): one of them, which occurred on week 26, was associated with trisomy 18 and the other, which occurred on week 29, was associated with treated twin-to-twin transfusion syndrome and death of one of the twins after treatment .The corrected text: Five of them showed spontaneous resolution (71%) and 2 resulted in intrauterine death (29%): one of them, which occurred in week 26, was associated with trisomy 18 and the other, which occurred in week 29, was associated with treated twin-to-twin transfusion syndrome and death of one of the twins after treatment .The original text: The prognosis of this entity is generally good, although the outcome largely depends on the size and location of associated anomalies. Cases of rupture, both pre- and postnatal, arrhythmia, fetal death, heart failure, and coronary insufficiency have been described . In these patients, serial control examinations are necessary to detect possible complications. In general, postnatal progression is good and surgery is not necessary in asymptomatic cases [19].The corrected text: The prognosis of this entity is generally good, although the outcome largely depends on the size and location of associated anomalies. Cases of rupture, both pre- and postnatal, arrhythmia, fetal death, heart failure, and coronary insufficiency have been described . In these patients, serial control examinations are necessary to detect possible complications. In general, postnatal progression is good and surgery is not necessary in asymptomatic cases [18].\u2009 Row 25: Williams et al. (2009) [3] should be Abi-Nader et al. (2009) [2].\u2009 Rows 29, 30, and 31: Abi-Nader et al. (2009) [2] should be Williams et al. (2009) [3].\u2009 Row 32: Williams et al. (2009) [3] should be Paoletti et al. (2012) [20].\u2009 Row 33: Paoletti and Robertson (2012) [20] should be Nam et al. (2010) [21].\u2009 Row 34: Nam et al. (2010) [21] should be Olor\u00f3n et al. (2011) [22].Errors in \u2009 Rows 4 and 11: Cavall\u00e9-Garrido et al.: the reference in the bibliography is [6].\u2009 Row 7: McAuliffe et al. [27] should be Del R\u00edo et al. [18].\u2009 Row 8: Pradhan et al. [28] should be Davidson et al. [15].\u2009 Row 9: McAuliffe et al. [27] should be Koshiishi et al. [17].\u2009 Row 10: Perlitz et al. [30] should be Menahem [31].\u2009 Row 12: Carles et al. [24] should be Johnson et al. [16].\u2009 Row 13: Cesko et al. [25] should be Bernasconi et al. [26].\u2009 Rows 14 and 15: Brachlow et al. [23] should be McAuliffe et al. [27].\u2009 Row 19: Williams et al. [3] should be Abi-Nader et al. [2].\u2009 Row 21: Abi-Nader et al. [2] should be Williams et al. [3].Errors in The corrected tables are shown in Tables"} +{"text": "The sections in QFP include the following: Determining the Client\u2019s Need for Services; Contraceptive Services; Pregnancy Testing and Counseling; Clients Who Want to Become Pregnant; Basic Infertility Services; Preconception Health Services; Sexually Transmitted Disease Services; and Related Preventive Health Services. In addition, the QFP includes an appendix entitled Screening Services for Which Evidence Does Not Support Screening.In April 2014, CDC published \u201cProviding Quality Family Planning Services: Recommendations of CDC and the U.S. Office of Population Affairs\u201d (QFP), which describes the scope of services that should be offered in a family planning visit and how to provide those services , and professional medical associations such as the American College of Obstetricians and Gynecologists and the American Academy of Pediatrics.2), and covered guidelines published during April 2014\u2013December 2015. This report summarizes recommendations from guidelines published during January 2016\u2013April 2017. CDC and the Office of Population Affairs prepared these updates by searching for materials from CDC, USPSTF, and other professional medical organizations that had recommendations referenced in the original QFP. When updated recommendations were identified, they were evaluated for changes in implications for providing family planning care. CDC and the Office of Population Affairs determined that none of the newly published recommendations marked a substantial shift in how family planning care should be provided, and therefore did not seek additional review to consider the implications for the QFP for this update. Technical reviews from clinical experts representing a broad range of family planning providers might be appropriate for future updates.The scope of preventive services related to reproductive health is constantly evolving as new scientific findings are published and clinical recommendations are modified accordingly. Being knowledgeable about the most current recommendations is an important step toward providing the highest quality care to patients. To keep QFP current with the latest recommendations, CDC and the Office of Population Affairs publish occasional updates that summarize newly published clinical recommendations. The first of these updates was published in March 2016 for emergency contraception.Revisions to the recommendations for postpartum women; women who are breastfeeding; women with known dyslipidemias, migraine headaches, superficial venous disease, gestational trophoblastic disease, sexually transmitted diseases (STDs), and human immunodeficiency virus (HIV) infection; and women who are receiving antiretroviral therapy.https://www.cdc.gov/mmwr/volumes/65/rr/rr6503a1_appendix.htmFor all 2016 updated recommendations, see Tables A1 and A2: Source: Curtis KM, Tepper NK, Jatlaoui TC, et al. U.S. medical eligibility criteria for contraceptive use, 2016. MMWR Recomm Rep 2016;65(No. RR-3).The 2016 CDC recommendations update earlier 2013 recommendations that address a select group of common, yet sometimes complex, issues regarding initiation and use of specific contraceptive methods.Recommendations have been updated regarding when to start regular contraception after UPA emergency contraceptive pills:Advise the woman to start or resume hormonal contraception no sooner than 5 days after use of UPA, and provide or prescribe the regular contraceptive method as needed. For methods requiring a visit to a health care provider, such as depo-medroxyprogesterone acetate (DMPA), implants, and intrauterine devices (IUDs), starting the method at the time of UPA use may be considered; the risk that the regular contraceptive method might decrease the effectiveness of UPA must be weighed against the risk of not starting a regular hormonal contraceptive method.The woman needs to abstain from sexual intercourse or use barrier contraception for the next 7 days after starting or resuming regular contraception or until her next menses, whichever comes first.Any nonhormonal contraceptive method can be started immediately after the use of UPA.The woman should be advised to have a pregnancy test if she does not have a withdrawal bleed within 3 weeks.New recommendations have been made regarding medications used to ease IUD insertion:Misoprostol is not recommended for routine use before IUD insertion. Misoprostol might be helpful in select circumstances .Paracervical block with lidocaine might reduce patient pain during IUD insertion.Source: Curtis KM, Jatlaoui TC, Tepper NK, et al. U.S. selected practice recommendations for contraceptive use, 2016. MMWR Recomm Rep 2016;65(No. RR-4).DepressionThe 2016 USPSTF recommendation for adults reaffirms the 2009 recommendation to screen all adults when staff-assisted depression care supports are in place. This replaces the 2009 recommendation regarding selective screening of adults.The 2016 USPSTF recommendation for adolescents aged 12\u201318 years reaffirms the 2009 recommendation to screen for major depressive disorder when systems are in place to ensure accurate diagnosis, effective treatment, and follow-up. The 2016 statement removes the recommendation of specific psychotherapies in recognition of decreased concern over the harms of pharmacotherapy in adolescents as long as they are adequately monitored.Sources:US Preventive Services Task Force. Screening for depression in adults. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016.US Preventive Services Task Force. Screening for depression in children and adolescents. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016.American College of Obstetricians and Gynecologists\u2019 Committee on Health Care for Underserved Women. Committee opinion no. 654: reproductive life planning to reduce unintended pregnancy.Obstet Gynecol2016;127:e66\u20139. 10.1097/AOG.000000000000131426942389CurtisKM, TepperNK, JatlaouiTC, U.S. medical eligibility criteria for contraceptive use, 2016.MMWR Recomm Rep2016;65(No. RR-3):1\u2013103. 10.15585/mmwr.rr6503a127467196CurtisKM, JatlaouiTC, TepperNK, U.S. selected practice recommendations for contraceptive use, 2016.MMWR Recomm Rep2016;65(No. RR-4):1\u201366. 10.15585/mmwr.rr6504a127467319American College of Obstetricians and Gynecologists\u2019 Committee on Obstetric Practice. Committee opinion no. 670: immediate postpartum long-acting reversible contraception.Obstet Gynecol2016;128:e32\u20137. 10.1097/AOG.000000000000158727454734American College of Obstetricians and Gynecologists\u2019 Committee on Gynecologic Practice Long-Acting Reversible Contraceptive Expert Work Group. Committee opinion no. 672: clinical challenges of long-acting reversible contraceptive methods.Obstet Gynecol2016;128:e69\u201377. 10.1097/AOG.000000000000164427548557PfeiferS, ButtsS, FossumG, ; Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society for Reproductive Endocrinology and Infertility. Optimizing natural fertility: a\u00a0committee opinion.Fertil Steril2017;107:52\u20138. 10.1016/j.fertnstert.2016.09.02928228319American College of Obstetricians and Gynecologists\u2019 Committee on Health Care for Underserved Women. Committee opinion no. 654: reproductive life planning to reduce unintended pregnancy.Obstet Gynecol2016;127:e66\u20139. 10.1097/AOG.000000000000131426942389KimDK, RileyLE, HarrimanKH, HunterP, BridgesCB. Advisory Committee on Immunization Practices recommended immunization schedule for adults aged 19 years or older\u2014United States, 2017.MMWR Morb Mortal Wkly Rep2017;66:136\u20138. 10.15585/mmwr.mm6605e228182599RobinsonCL, RomeroJR, KempeA, PellegriniC; Advisory Committee on Immunization Practices (ACIP) Child/Adolescent Immunization Work Group. Advisory Committee on Immunization Practices recommended immunization schedule for children and adolescents aged 18 years or younger\u2014United States, 2017.MMWR Morb Mortal Wkly Rep2017;66:134\u20135. 10.15585/mmwr.mm6605e128182607US Preventive Services Task Force. Folic acid supplementation for the prevention of neural tube defects: preventive medication. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2017. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medicationUS Preventive Services Task Force. Depression in adults: screening. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/depression-in-adults-screening1US Preventive Services Task Force. Depression in children and adolescents: screening. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/depression-in-children-and-adolescents-screening1US Preventive Services Task Force. Syphilis infection in nonpregnant adults and adolescents: screening. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/syphilis-infection-in-nonpregnant-adults-and-adolescentsUS Preventive Services Task Force. Breast cancer: screening. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/breast-cancer-screening1US Preventive Services Task Force. Gynecological conditions: periodic screening with the pelvic examination. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2017. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/gynecological-conditions-screening-with-the-pelvic-examinationUS Preventive Services Task Force. Genital herpes infection: serologic screening. Rockville, MD: US Department of Health and Human Services, Agency for Healthcare Research and Quality; 2016. https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/genital-herpes-screening11. GavinL, MoskoskyS, CarterM, . Providing quality family planning services: recommendations of CDC and the U.S. Office of Population Affairs.MMWR Recomm Rep2014;63(No. RR-04).247596902. GavinL, PazolK. Update: providing quality family planning services\u2014recommendations from CDC and the U.S. Office of Population Affairs, 2015.MMWR Morb Mortal Wkly Rep2016;65:231\u20134. 10.15585/mmwr.mm6509a326963363"} +{"text": "Cellular & Molecular Biology Letters launched with BioMed Central in January, 2016. Previously, its publishers were Walter De Gruyter in 2015, and Springer from 2006\u20132014. Content from 2015 (Volume 20) is available in the archive."} +{"text": "Corrigendum to:https://doi.org/10.1002/ece3.2528Casties I, Seebens H, Briski E (2016) Importance of geographic origin for invasion success: a case study of the North and Baltic Seas versus the Great Lakes\u2010St. Lawrence River region. Ecology and Evolution, 6(22), 8318\u20138329. The authors of the paper Casties et\u00a0al. (2016) want to note that Figure 1 appeared incorrectly. Please find the correct figure below."} +{"text": "Correction to:npj Systems Biology and Applications (2016) 2, 16002; doi:10.1038/npjsba.2016.2; published online 3 March 2016After online publication of this article, the authors noticed an error in the input files used for running the Prize Collecting Steiner Forest algorithm for With publication of this corrigendum, rectified"} +{"text": "De Novo Sequencing and Assembly Analysis of the Pseudostellaria heterophylla Transcriptome. PLoS ONE 11(10): e0164235.The second author\u2019s name is incorrect. The correct name is: Wei Zheng. The correct citation is: Li J, Zheng W, Long D, Ding L, Gong A, Xiao C, et al. (2016) P. heterophylla cultivar \u2018Shitai 1\u2019 was selected and grown in a commercial planting base in Shibing County, Guizhou Province, China.There is an error in the first sentence of the Methods section. The correct sentence is:"} +{"text": "Scientific Reports 10.1038/s41598-017-16850-z, published online 29 November 2017Correction to: The Acknowledgements section in this Article is incomplete.\u201cAdvanced Research Foundation, grant #7/019/2014-2017, supported the laser inscription experiments. Ministry of Education of Science of Russian Federation, grant #14.Z50.31.0009, have funded measurement, math treatment and analysis of the obtained data. The authors are grateful to Dr. R. Drevinskas for discussions of methods for measuring the optical phase.\u201dshould read:\u201cAdvanced Research Foundation, grant #7/019/2014-2017, supported the laser inscription experiments. Ministry of Education of Science of Russian Federation, grant #14.Z50.31.0009, have funded measurement, math treatment and analysis of the obtained data. A part of the study related to the measurements of refractive index change was also supported by the Royal Society (UK) International Exchanges Program (Grant IE150203). The authors are grateful to Dr. R. Drevinskas for helpful discussions.\u201d"} +{"text": "Correction to:Cell Discovery (2016) 2, 16037; doi:10.1038/celldisc.2016.37; Published 18 October 2016x axis and y axis were left out. The corrected In the initial published version of this article, an error was made in"} +{"text": "Scientific Data 3:160115 doi: 10.1038/sdata.2016.115 (2016); Published 20 December 2016; Updated 14 March 2017The original version of this Data Descriptor contained a typographical error in the spelling of the author A. Lamontanara, which was incorrectly given as A. Lamontara. This has now been corrected in the PDF and HTML versions of the Data Descriptor."} +{"text": "Correction to:Cell Death and Disease (2016) 7, e2388; doi:10.1038/cddis.2016.260; published online 29 September 2016Cell Death and Disease in 2016, the authors noted an error contained in Since the publication of this article in The corrected article appears online together with this corrigendum.The authors would like to apologize for any inconvenience caused."} +{"text": "Correction to: Translational Psychiatry (2016) 6, e713; doi:10.1038/tp.2015.209; published online 19 January 2016The authors noticed that an omission was made in the Acknowledgements section. The omitted data appear below.This project was partially funded by a grant from the Pennsylvania Department of Health."} +{"text": "Correction to:Clinical & Translational Immunology (2017) 6, e126; doi:10.1038/cti.2016.87; published online 20 January 2017.The volume number in the PDF of the above paper was published incorrectly. It should be 6 instead of 5. This has now been corrected in the PDF.The publishers wish to apologize for any inconvenience caused."} +{"text": "Dear Editors,Acta Neuropathol Commun. 2017; 5: 13 [We read with interest the publication by Wei et al., Mitochondrial DNA Point Mutations and Relative Copy Number in 1363 Disease and Control Human Brains, 7; 5: 13 . We disaSincerely,David K. Simon, MD PhD"} +{"text": "CDC is assisting ministries of health and working with other organizations to end the ongoing epidemic of Ebola virus disease (Ebola) in West Africa . The updAccording to the latest World Health Organization update on November 14, 2014 , a totalThe 2,705 new Ebola cases reported during October 19\u2013November 8 were more widely distributed geographically among districts in Guinea and Liberia compared with the 2,809 new cases reported during September 28\u2013October 18 .As of November 8, the highest cumulative incidence rates were reported by two prefectures in Guinea (Gu\u00e9ck\u00e9dou and Macenta), four counties in Liberia , and five districts in Sierra Leone . Evidenchttp://www.cdc.gov/vhf/ebola/outbreaks/guinea/index.html. The most up-to-date infection control and clinical guidelines on the 2014 Ebola epidemic in West Africa are available at http://www.cdc.gov/vhf/ebola/hcp/index.html.The latest updates on the 2014 Ebola epidemic in West Africa, including case counts, are available at"} +{"text": "AbstractOphiuroidea stored at the Italian National Antarctic Museum are presented, corresponding to 1595 individuals that belong to 35 species and 17 genera. Specimens were collected in 106 different sampling stations at depths ranging from 21 to 1652 m in the framework of 14 Antarctic expeditions to the Ross Sea, one to the Antarctic Peninsula, and one to the Falkland Islands . Three species, Amphiurajoubini Koehler, 1912, Amphiura (Amphiura) angularis Lyman, 1879, and Ophiuraflexibilis , are reported as new records for the Terra Nova Bay area, whose check-list of species increases from 15 to 18 species. The determination of these three new records was based both on morphological identification and molecular analyses (COI barcoding). Some of the genetically characterised specimens were also documented through photogrammetry and micro-computed tomography and represent the first bulk of 3D models that will be available through the MNA and Sketchfab websites, both for research and educational purposes.The distributional records of Museum collections have always been indispensable resources for biodiversity studies by providing data over a vast time span . The recOphiuroidea collected in the framework of several recent scientific expedition performed in the Southern Ocean and which are now permanently stored and curated at the Italian National Antarctic Museum . The Ross Sea expeditions were the Italian National Antarctic Program (PNRA) expedition \u201cIII\u201d (1987/1988), \u201cV\u201d (1989/1990), \u201cIX\u201d (1993/1994), \u201cX\u201d (1994/1995), \u201cXIII\u201d (1997/1998), \u201cXIV\u201d (1998/1999), \u201cXV\u201d (1999/2000), \u201cXVII\u201d (2001/2002), \u201cXIX\u201d (2003/2004), \u201cXXV\u201d (2009/2010), \u201cXXVII\u201d (2011/2012), \u201cXXVIII\u201d (2012/2013), \u201cXXIX\u201d (2013/2014) and the New Zealand \u201cTAN0802 IPY-CAML Oceans Survey 20/20\u201d voyage (2008). Additional samples collected outside the Ross Sea were obtained from the German ANT-XXIX/3, PS81 expedition (2013) and the US ICEFISH 2004 voyage (2004).In this paper new distributional data is provided for MNA collections, ii) helping researchers in crosschecking morphological data of sequenced species from specific geographic areas (in this case species from the Ross Sea and Terra Nova Bay in particular), and iii) producing materials useful for educational purposes. Virtual collections guarantee rapid and simultaneous access to accurate virtual representations of important museum materials, such as type materials (e.g. MNA 2644 and MNA 7784) and on photogrammetry for larger ones (i.e. MNA 7368). The distributional dataset is the fourth MNA contribution to the Antarctic Biodiversity Portal, which is the thematic Antarctic node for both the Ocean Biogeographic Information System (AntOBIS) and the Global Biodiversity Information Facility (ANTABIF) (http://www.biodiversity.aq). Previous contributions were: In parallel to this data set a series of ophiuroid 3D models have also been developed based on \u2018molecular vouchers\u2019 that are released with the aim of: i) providing the widest accessibility to the als e.g. or, as ials e.g. for smalProject title: Antarctic Ophiuroidea in the collection of the Italian National Antarctic Museum (MNA)Curator and Promoter: Stefano SchiaparelliPersonnel: Matteo Cecchetto, Maria Chiara Alvaro, Claudio Ghiglione, Alice Guzzi, Claudio Mazzoli, Paola Piazza, Stefano SchiaparelliFunding sources: The Ophiuroidea were collected during different Italian, New Zealand, German and American research projects and expeditions to Antarctica funded by: i) the Italian National Antarctic Research Program (PNRA), ii) the Ministry for Primary Industries , iii) the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research and iv) the National Science Foundation grant to H. William Detrich (North Eastern University). The full list of sponsors is listed below:PNRA research projectsItalian :\u2022 2.1.4.6 (Necton e risorse da pesca) \u2022 3.2.1.2.5 (Benthos) and 3.2.1.4 (Oceanografia geologica) \u2022 2d.2 (Ecology and Biogeochemistry of the Southern Ocean) \u2022 2d.2 (Ecology and Biogeochemistry of the Southern Ocean) \u2022 2b.3.1 (Struttura e dinamica delle cenosi marine di Baia Terra Nova) PageBreak\u2022 2b.3.1 (Struttura e dinamica delle cenosi marine di Baia Terra Nova) \u2022 8.5 (L\u2019area marina protetta di Baia Terra Nova: struttura e variazioni a breve e lungo termine) \u2022 4.7 \u2022 8.5 (L\u2019area marina protetta di Baia Terra Nova: struttura e variazioni a breve e lungo termine) \u2022 1.3 \u2022 2002/8.6 \u2022 2006/08.01 \u2022 2010/A1.10 \u2022 2009/A1.09 \u2022 2010/A1.10 Pleuragrammaantarcticum) \u2022 2010/A1.11 \u2022 2013/AZ1.18 (RAISE: Ricerche integrate sulla ecologia dell\u2019Antarctic Silverfish nel MarE di Ross) New Zealand research projects:NIWA)\u2022 IPY-CAML voyage - Census of Antarctic Marine Life programme - funded by the Government of New Zealand and administered by the Ocean Survey 20/20 CAML Advisor Group \u2022 Project 3.1 (M.C. Alvaro PageBreakAmerican research project:http://www.icefish.neu.edu) (M. Vacchi legit)\u2022 ICEFISH 2004 Cruise expedition, the first comprehensive international survey of the fishes of the Sub-Antarctic marine habitat and southeast Falkland Islands . The bathymetric range of sampling stations was from 21 to 1652 m.Design description: Data were assembled by revising Ophiuroidea voucher specimens curated by the Italian National Antarctic Museum collection (MNA), Section of Genoa, Genoa . These samples were collected in the framework of the above reported research expeditions, which had different aims and geographical scopes.Method step description: See sampling description below and flowchart of Figure Study extent description: The Ophiuroidea distributional data here considered originated from 106 different sampling stations ranging between 21 and 1652 metres of depth , of the National Institute of Water and Atmospheric Research (NIWA), of the Alfred Wegener Institute (AWI) and of the USA Antarctic Program. Sampling was performed through the deployment of a variety of sampling gears. Benthic sampling under the Italian PNRA was mainly performed by using a heterogeneous set of dredges (i.e. Charcot dredge and Triangular dredges) and Van Veen grabs of different volumes, plus an unconventional set of gears for sampling benthic fauna such as gillnets, trammel nets, long lines, also comprising a mid-water trawls that opportunistically collected benthic specimens due to accidental contact with the bottom during gear deployment failures. Two samples were collected during the \u201cXVII\u201d and \u201cXXV\u201d PNRA expeditions by SCUBA divers along the rocky cliffs of Tethys Bay. The NIWA expedition \u201cTAN0802 IPY-CAML\u201d (2008) used an epibenthic sled and a rough-bottom trawl (ORH). The German expedition \u201cANT-XXIX/3\u201d (PS81) collected the material through the deployment of an Agassiz trawl while an Otter trawl was used to sample the single specimen collected during the ICEFISH 2004 cruise. After the material has been acquired by the MNA and included in the collections, all the specimens were classified to the lowest possible taxonomical resolution on a morphological base mainly by following PNRA projects 2010/A1.10 \u201cBAMBi\u201d (Barcoding of Antarctic Marine Biodiversity) and PNRA 2013/AZ1.15 \u201cISOBIOTOX\u201d . DNA extraction and sequencing of partial cytochrome c oxidase subunit 1 (CO1) was carried out at the Canadian Centre for DNA Barcoding and sequences were uploaded on the BOLD platform . The primers used for amplification were LCOech1aF1 and HCO2198 (http://iobis.org/data/schema-and-meta-data) and according to the SCAR-MarBIN Data Toolkit (available at http://www.scarmarbin.be/documents/SM-FATv1.zip). The dataset was uploaded into AntOBIS (the Antarctic thematic node of OBIS). Vouchers stored at the Italian National Antarctic Museum (MNA), Section of Genoa, Genoa are preserved, according to the different lots, in 75% ethanol, frozen (-20\u00b0C) or dried obtained by sequencing a total of 167 specimens representative of all the different morphospecies found here. The outcomes of the molecular study will be the subject of another publication and here we release only the COI sequences corresponding to the specimens that have been used to produce 3D models.PageBreakat various steps in order to produce quality data and make consistent cross-references between the database and samples\u2019 labels to manage its collections and link all the data to the physical samples. Geo-referencing on board of the different research vessels was based on the interpolation of GPS satellite receivers and a gyrocompass. Station coordinates and sampling events were recorded during sampling activities based on various GPS systems.During all the phases of sorting, classification, and storage of samples at the Italian National Antarctic Museum, quality control and data cleaning have been undertaken els Fig. . The MNAGeneral taxonomic coverage description: This dataset focused on the Class Ophiuroidea and includes a total of 1595 specimens belonging to 17 genera and 35 different species. In the Southern Ocean, the Class Ophiuroidea numbers 219 species , thus representing one of the most important benthic groups of the Antarctic and sub-Antarctic regions. Amphiurajoubini Koehler, 1912, one specimen of Amphiura (Amphiura) angularis Lyman, 1879, and four specimens of Ophiuraflexibilis . These records have thus to be added to the Terra Nova Bay checklist provided by Chiantore et al. (2006) and increase the check-list of Terra Nova Bay ophiuroid species from 15 to 18. The determination of these new records was also molecularly cross-checked (and confirmed) through COI barcodes. The outcomes of the barcoding effort on Terra Nova Bay ophiuroids and other echinoderm classes will be the subject of a separate contribution.PageBreakKingdom: AnimaliaPhylum: EchinodermataClass: OphiuroideaOrder: EuryalidaFamily: GorgonocephalidaeGenera: Astrotoma, Astrochlamys, GorgonocephalusSpecies: Astrochlamysbruneus; Astrochlamyssol; Astrotomaagassizii; Gorgonocephalus sp.Kingdom: AnimaliaPhylum: EchinodermataClass: OphiuroideaOrder: OphiuridaFamily: Amphiuridae, Ophiacantidae, Ophiolepididae, Ophiuridae, OphiuridaeGenera: Amphiura; Ophiacantha; Ophiocamax; Ophioceres; Ophiocten; Ophiogona; Ophioleuce; Ophiolimna; Ophionotus; Ophioperla; Ophioplinthus; Ophiosparte; Ophiosteira; OphiuraSpecies: Amphiuraalgida; Amphiura (Amphiura) angularis; Amphiurabelgicae; Amphiurajoubini; Amphiura sp.; Ophiacanthaantarctica; Ophiacanthapentactis; Ophiacantha sp.; Ophiacanthavivipara; Ophiocamaxgigas; Ophioceresincipiens; Ophioctendubium; Ophioctenmegaloplax; Ophiogonadoederleini; Ophioleuceregulare; Ophiolimnaantarctica; Ophionotusvictoriae; Ophioperlakoehleri; Ophioplinthusbrevirima; Ophioplinthusgelida; Ophioplinthusmartensi; Ophioplinthus sp.; Ophiospartegigas; Ophiosteiraantarctica; Ophiosteirabullivanti; Ophiosteiraechinulata; Ophiuraambigua; Ophiura (Ophiuroglypha) carinifera; Ophiuracrassa; Ophiuraflexibilis; Ophiura sp.General geographic description: The Ross Sea, the Bransfield Strait in the Antarctic Peninsula and southeast of the Falkland Islands Figure , 4 and 5PNRA III expedition: -74.7125 and -74.79167; 164.03000 and 164.13667PNRA V expedition: -74.68745 and -74.87100; 164.02433 and 164.26083PNRA IX expedition: -74.72000; 164.14000PNRA X expedition: -74.69320 and -74.71688; 164.04272 and 164.14700PNRA XIII expedition: -74.68750; 164.14550PNRA XIV expedition: -74.68762 and -74.89950; 163.93748 and 164.10728PageBreakPNRA XV expedition: -74.71343 and -74.72053; 164.17060 and 164.17783PNRA XVII expedition: -72.20967 and -77.65133; 164.03418 and -166.79183PNRA XIX expedition: -71.28833 and -74.82167; 164.19167 and 170.65333PNRA XXV expedition: -74.69027 and -74.69768; 164.10255 and 164.13108PNRA XXVII expedition: -74.68562 and -74.71337; 164.03502 and 164.14903PNRA XXVIII expedition: -74.68090 and -74.77737; 164.05285 and 164.23640PNRA XXIX expedition: -74.68677 and -74.72283; 164.12278 and 164.24206New Zealand TAN0802 IPY-CAML voyage: -66.93250 and -73.24817; 170.87700 and 178.72367German ANT-XXIX/3 (PS81) expedition: -62.43250 and -63.00883; -56.28767 and -58.68483American ICEFISH 2004 cruise: -52.48498; -54.86978PNRA III expedition (1987/1988): January 15, 1988 - February 2, 1988PNRA V expedition (1989/1990): December 25, 1989 - December 29, 1989PNRA IX expedition (1993/1994): December 17, 1993PNRA X expedition (1994/1995): January 25, 1995 - February 8, 1995PNRA XIII expedition (1997/1998): February 21, 1998PNRA XIV expedition (1998/1999): January 25, 1999 - February 10, 1999PNRA XV expedition (1999/2000): February 10, 2000PNRA XVII expedition (2001/2002): January 4, 2002 - February 10, 2002PNRA XIX expedition (2003/2004): February 4, 2004 - February 21, 2004PNRA XXV expedition (2009/2010): December 10, 2009 - January 11, 2010PNRA XXVII expedition (2011/2012): January 27, 2012 - February 3, 2012PNRA XXVIII expedition (2012/2013): January 9, 2013 - January 31, 2013PNRA XXIX expedition (2013/2014): January 16, 2014 - February 3, 2014New Zealand TAN0802 IPY-CAML voyage (2008): February 19, 2008 - March 14, 2008German ANT-XXIX/3 (PS81) expedition (2013): January 26, 2013 - March 5, 2013American ICEFISH 2004 cruise (2004): June 26, 1905Parent collection identifier: Italian National Antarctic Museum (MNA) Section of Genoa, ItalyCollection name: MNA (Section of Genoa) Invertebrate Collection \u2013 Antarctic and sub-Antarctic OphiuroideaSpecimen preservation method: Part of the material collected during the older expeditions (roughly from 1988 to 2004) was fixed in ethanol or formalin immediately after isolation and kept in tubes or vials for further studies, while the remaining samples PageBreakwere dried out to facilitate morphological identifications. The specimens corresponding to these older expeditions are therefore generally not usable for molecular analyses. Instead, the material collected during recent expeditions (i.e. roughly from 2005 to 2014) was fixed in 75% ethanol or frozen immediately after isolation and kept in the same condition in order to preserve the DNA quality and integrity .ity Fig. . MoleculVirtual collection of vouchers and 3D models: 3D models were obtained from three barcoded specimens of the species Ophiosteiraechinulata (MNA 2644) and 3.95 \u03bcm (sample MNA 2644), respectively. Three-dimensional rendering and animations were performed with CTVox software package (Bruker).44) Fig. , O.antaca MNA 774 Fig. . The firMNA 7368) was produced by using photogrammetry and assembling pictures taken with a Nikon D700 equipped with a Nikon AF-S Micro Nikkor 105 mm (1: 2.8G ED) lens (corresponding to a resolution of 4256 x 2832 and a pixel size of 8.46 x 8.46 \u03bcm) in Agisoft Photoscan Professional 1.3.1. The MNA 3D models based on materials curated at the museum will be available from the MNA web site (www.mna.it) and from the Sketchfab gallery dedicated to cultural heritage and museums (https://sketchfab.com/MNA).The third model . The Darwin Core elements included in the dataset are: occurrence ID , institution code , basis of record , preparations (i.e. the preservation method), catalogue number , individual PageBreakcount, sampling protocol (i.e. sampling gear), event date , event remarks (i.e. expedition), field number (i.e. sampling station), field notes , maximum depth in meters, decimal latitude (DD), decimal longitude (DD) and scientific name.PageBreakObject name: MNA (Section of Genoa) \u2013 Antarctic and sub-Antarctic OphiuroideaCharacter encoding: UTF-8Format name: Darwin Core Archive formatFormat version: 1.0PageBreakDistribution: http://ipt.biodiversity.aq/resource.do?r=mna_antarctic_ophiuroideaLanguage: EnglishMetadata language: EnglishLicense of use: This dataset [MNA (Section of Genoa) \u2013 Antarctic and sub-Antarctic Ophiuroidea] is made available under the Creative Commons Attribution License (CC-BY) 4.0: http://www.creativecommons.org/licenses/by/4.0/legalcodeDate of metadata creation: 2017-05-04Hierarchy level: Dataset"} +{"text": "There is an error in reference 27. The correct reference is: Maru\u0161i\u0107 A, Bo\u0161njak L, Jeron\u010di\u0107 A. A systematic review of research on the meaning, ethics and practices of authorship across scholarly disciplines. PLoS ONE. 2011;6: e23477. doi: 10.1371/journal.pone.0023477There is an error in reference 52. The correct reference is: Ha\u00fcssler C, Sauermann H. Credit where credit is due? The impact of project contributions and social factors on authorship and inventorship. Res Policy. 2013;42: 688\u2013703.The second sentence of the fourth paragraph in the Introduction section should have cited reference 52 instead of 27.The correct sentence should read: Researchers may award guest authorship to colleagues in hopes of receiving reciprocal authorship on that colleague\u2019s publications or to increase the likelihood of an article\u2019s publication due to that colleague\u2019s political or reputational influence [52].The fourth sentence of the last paragraph in the Introduction section should have cited references 36, 53 instead of 28, 37. In the same sentence, the references 38,39,40,41,42,43,44,45,46,47,48 should be replaced with the following omitted references:Drenth JPH. Multiple authorship: the contribution of senior authors. JAMA J Am Med Assoc. 1998;280: 219\u2013221.Regalado A. Multiauthor papers on the rise. Science. 1995;268: 25.Modi P, Hassan A, Teng CJ, Chitwood Jr WR. \u201cHow many cardiac surgeons does it take to write a research article?\u201d: seventy years of authorship proliferation and internalization in the cardiothoracic surgical literature. J Thorac Cardiovasc Surg. 2008;136: 4\u20136.Onwude JL, Staines A, Lilford RJ. Multiple author trend worst in medicine. BMJ. 1993;306: 1345.Borry P, Schotsmans P, Dierickx K. Author, contributor or just a signer? a quantitative analysis of authorship trends in the field of bioethics. Bioethics. 2006;20: 213\u2013220.Epstein RJ. Six authors in search of a citation: villains or victims of the Vancouver convention? BMJ. 1993;306: 765\u2013767.https://www.geosociety.org/gsatoday/archive/17/7/pdf/i1052-5173-17-7-44.pdf.Engelder T. The coupling between devaluation of writing in scientific authorship and inflation of citation indices. GSA Today. 2007;17: 44\u201345. Available from: McDonald RJ, Neff KL, Rethlefsen ML, Kallmes DF. Effects of author contribution disclosures and numeric limitations on authorship trends. Mayo Clin Proc. 2010;85: 920\u2013927.Shaban S. Multiple authorship trends in prestigious journals from 1950 to 2005. Saudi Med J. 2007;28: 927\u2013932.http://ip-science.thomsonreuters.com/m/pdfs/klnl/8428096/swmultiauthor.pdf.King C. Multiauthor paper redux: a new peak at new peaks. Science Watch Nov-Dec. 2007; Available from: Cozzarelli NR. Responsible authorship of papers in PNAS. Proc Natl Acad Sci. 2004;101: 10495.The references given in the sixth sentence of the last paragraph in the Introduction section are incorrect. In this sentence, the references 41, 45 should be replaced with the following omitted references:Epstein RJ. Six authors in search of a citation: villains or victims of the Vancouver convention? BMJ. 1993;306: 765\u2013767.McDonald RJ, Neff KL, Rethlefsen ML, Kallmes DF. Effects of author contribution disclosures and numeric limitations on authorship trends. Mayo Clin Proc. 2010;85: 920\u2013927.The tenth sentence of the first paragraph in the Discussion section should have cited reference 27 instead of 52.The correct sentence should read: Our cluster analysis revealed two general groups among middle authors, one characteristic of more senior level researchers and the other more typical of junior level researchers [27].The structure of all affected sentences in the original article remains the same."} +{"text": "Correction to:Molecular Psychiatry advance online publication, 18 October 2016; doi:10.1038/mp.2016.179Following publication of the above article, the authors noticed that an obsolete version of the Supplementary Information (DOCX 18 kb)"} +{"text": "Correction to:Heredity (2016) 118, 52\u201363; doi:10.1038/hdy.2016.99; published online 2 November 2016Updated online 7 December 2016: This article was originally published under NPG's License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly.The corrected article appears in this issue together with this corrigendum. The publisher wishes to apologize for any inconvenience caused."} +{"text": "Retraction: Data in this paper was plagiarized from \u201cClinical application of contrast-enhanced ultrasonography in diagnosis of superficial lymphadenopathy,\u201d in the Journal of Ultrasound in Medicine. 2010; 29:735-40.Footnotes: The online version of the original article can be found under doi.52416-52422. doi: 10.18632/oncotarget.9385Original article: Oncotarget. 2016; 7:"} +{"text": "CDC is assisting ministries of health and working with other organizations to end the ongoing epidemic of Ebola virus disease (Ebola) in West Africa . The updAccording to the latest World Health Organization update on December 10, 2014 , a totalThere were 4,281 new Ebola cases reported during the 4-week period of November 9\u2013December 6, compared with the 2,705 new cases reported during the 3-week period of October 19\u2013November 8 .As of December 6, the highest cumulative incidence rates were reported by two prefectures in Guinea (Gu\u00e9ck\u00e9dou and Macenta), six counties in Liberia , and six districts in Sierra Leone . Evidenchttp://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/index.html. The most up-to-date infection control and clinical guidelines on the 2014 Ebola epidemic in West Africa are available at http://www.cdc.gov/vhf/ebola/hcp/index.html.The latest updates on the 2014 Ebola epidemic in West Africa, including case counts, are available at"} +{"text": "AbstractIotarphiarufobrunnea Lee & Ahn, sp. n. is described from Tasmania. The new species is compared with another species of the genus, Iotarphiaaustralis Cameron. A description, habitus photograph and illustrations of the diagnostic characters are provided. Iotarphia Cameron. After detailed examination of the specimens and comparison with Iotarphiaaustralis Cameron (type species of Iotarphia), we concluded that these specimens represent a new species of the genus.While working on aleocharine beetles collected by the second author from the eastern and southern seashores in Tasmania, Australia, we found specimens very similar to the athetine genus PageBreakIotarphia and its single described species have been recorded only in a \u201cmaritime habitat\u201d from New South Wales and from Tasmania, both in Australia , Coal Point, Bruny Island , collected 25.ix.2014, A.W. Osborn. Paratypes: 4, of which 3 (QVM:2016:12:1052 to 1054) share common collection data with holotype, and 1 (QVM:2014:12:0125) collected from Lighthouse Bay, Bruny Is., collected 24.ix.2014, A.W.Osborn.Queen Victoria Museum and Art Gallery, Launceston, Tasmania (QVMAG).All type specimens have been placed in the PageBreakyellow, elytra reddish brown except for basal darker region; surface slightly glossy, densely pubescent with fine microsculpture. Head. Slightly transverse, approximately 1.1\u20131.2 times as wide as long, widest across eyes, narrower than pronotum; eyes slightly large and prominent, about 1.2 times as long as temples; gular sutures moderately separated, slightly diverged basally. Antennae ; 40:43:46:48:78 (mesotarsus); 48:55:58:54:80 (metatarsus); one empodial seta present, shorter than claw. Abdomen. Subparallel-sided; surface glossy and densely pubescent, with transverse and imbricate microsculpture; male tergite VIII , Tasmania, Australia Fig. .Iotarphiaaustralis, but can be distinguished by the characters provided in Table 43.34211\u00b0S and 147.32178\u00b0E) and (ii) from a sandy substrate in which some small rocks were present within the littoral zone at Lighthouse Bay .This species is similar to Staphylinidae species in the Tasmanian fauna to five: Iotarphiaaustralis (= Psammoporadelittlei Pace), Iotarphiarufobrunnea Lee & Ahn, sp. n., Teropalpuspictipes (Lea), Cafiuspacificus (Erichson), and Remussericeus (Holme).The description of the new species within the present paper brings the total number of coastal"} +{"text": "Correction to:Journal of Human Hypertension (2017) 31, 305\u2013312; doi:10.1038/jhh.2016.78; published online 22 December 2016The text of the licence type for this paper was incorrect on the full text version. The following is the correct text:The publishers wish to apologise for their error."} +{"text": "AbstractOpadometa are difficult to associate with conspecific females, and sex-matching errors may persist in the taxonomic literature. Recommended best practices for definitive sex matching in this genus suggest finding a male in the web of a female, or better yet, mating pairs.Males of Opadometa was observed hanging on a frame line of the web of a female Opadometasarawakensis, a species for which the male was previously undescribed. This occurred during a tropical ecology field course held at the Danau Girang Field Centre in Sabah, Malaysia. A taxonomic description was completed as a course activity.A male Opadometa species. Opadometa Males\u201d, in which they detailed the complexities of associating the rarely collected males of Opadometa with conspecific females. They included photographs of a male Opadometa collected in the vicinity of the red and blue female, but warned that it would be premature to conclude that these are conspecific. Males of Opadometa are rare in collections and notoriously difficult to associate with conspecific females, which are more than twice their length and much heavier. Confirmation of male-female conspecificity, they state, should be accepted, \u201c\u2026only if the males and females are found in the same web, or better still, are seen copulating.\u201d (p. 260).The cover of Koh and Ming\u2019s 2014 field guide to the Spiders of Borneo was graced with a striking but at the time undescribed red and blue Opadometa species based on a female specimen from Sarawak, Malaysia. The male was not described, and Dzulhelime et al. echoed some of the sentiment expressed by Koh and Ming regarding the difficulties of associating male and female Opadometa.Opadometa. The female spider matched Dzulhelmi et al.\u2019s (2015) description of Opadometasarawakensis. A survey of orb web-building spiders near DGFC found no other Opadometa species. The students resolved, along with lecturers and field station scientific staff, to describe the male and provide additional data on the female, as well as data on the ecology and behavior of the species, and submit their results in the form of a manuscript before the end of the course. This is the second contribution to spider taxonomy and natural history to be produced in this way in Sabah, Malaysia, found a mature male at the margin of the web of a red and blue this way .Opadometa are currently cataloged , O.fastigata , O.kuchingensis Dzulhelmi & Suriyanti, 2015, and O.sarawakensis Dzulhelmi & Suriyanti, 2015 were established on the order of 100 years ago and have not been revisited (Four species (plus eight subspecies) of ataloged : O.gratti, 2015 . The typhis name ; Fig. 1.evisited ; their sO.grata have been collected together with females of O.fastigata . Examination of illustrations of the male pedipalp in the legacy taxonomic literature reveals a clue: the Cymbial Basal Process (CBP) of specimens from New Guinea and New Hebrides extend more or less retrolaterally from the cymbium before curving distally ; males from elsewhere have the CBP extend nearly posteriorly before curving Dzulhelmi & Suriyanti, in Type status:Other material. Occurrence: catalogNumber: DGFCW2018022300; recordedBy: Jeremy Miller and Christian Freund; individualCount: 2; sex: 1 male, 1 female; lifeStage: adult; Taxon: scientificName: Opadometasarawakensis Dzulhelmi & Suriyanti, 2015; Location: country: Malaysia; stateProvince: Sabah; locality: Danau Girang Field Centre trails; verbatimElevation: 23 m; decimalLatitude: 5.41619; decimalLongitude: 118.0426; Event: eventDate: 2018-02-23; Record Level: institutionID: Universiti Malaysia Sabah; collectionID: Institute for Tropical Biology and Conservation, Borneensis; institutionCode: UMS; collectionCode: BORN; basisOfRecord: PreservedSpecimenType status:Other material. Occurrence: catalogNumber: DGFCW2018022402; recordedBy: Jeremy Miller, Christian Freund, Liselotte Rambonnet, Lianne Koets, Natasha Zulaikha, and Jozsef Geml; individualCount: 1; sex: female; lifeStage: adult; Taxon: scientificName: Opadometasarawakensis Dzulhelmi & Suriyanti, 2015; Location: country: Malaysia; stateProvince: Sabah; locality: Danau Girang Field Centre trails; verbatimElevation: 23 m; decimalLatitude: 5.40999; decimalLongitude: 118.04204; Event: eventDate: 2018-02-24; Record Level: institutionID: Universiti Malaysia Sabah; collectionID: Institute for Tropical Biology and Conservation, Borneensis; institutionCode: UMS; collectionCode: BORN; basisOfRecord: PreservedSpecimenType status:Other material. Occurrence: catalogNumber: DGFCW2018022611; recordedBy: Jeremy Miller and Christian Freund; individualCount: 1; sex: female; lifeStage: adult; Taxon: scientificName: Opadometasarawakensis Dzulhelmi & Suriyanti, 2015; Location: country: Malaysia; stateProvince: Sabah; locality: Danau Girang Field Centre trails; verbatimElevation: 22 m; decimalLatitude: 5.41623; decimalLongitude: 118.04273; Event: eventDate: 2018-02-26; Record Level: institutionID: Universiti Malaysia Sabah; collectionID: Institute for Tropical Biology and Conservation, Borneensis; institutionCode: UMS; collectionCode: BORN; basisOfRecord: PreservedSpecimenMale: from Sabah, Malaysia (DGFCW2018022300). Prosoma uniform orange. Eight eyes in two rows, with the medians closer together than to the laterals; posterior median eyes oriented slightly toward the front; lateral eyes touching. Sternum dusky orange, darker posteriorly. Chelicerae orange, enlarged, diverging distally, armed in front and basolaterally with strong macrosetae; macrosetae absent from frontal-basal region Fig. a; femur 3Abdomen gray dorsally with silvery patches and an anteriodorsal dark spot, black posteriorly and ventrally with two posteriolateral and one ventral orange spot, with a small anteriolateral black spot and a larger posteriolateral black spot, which joins with the black ventral marking.Palpal trochanter, femur, and tibia very long Fig. c. Cymbiahere). Our observations of females from DGFC largely agree with the description in 44Female: For description and diagnosis of female, see Male (DGFCW2018022300): Total length 2.8; carapace length 1.4, width 0.9; abdomen length 1.4, width 0.9, height 0.9.Female (DGFCW2018022300): Total length 6.2; carapace length 3.6, width 2.4; abdomen length 5.0, width 2.8, height 2.7.Female (DGFCW2018022402): Total length 8.1; carapace length 3.4, width 2.7; abdomen length 7.6, width 4.2, height 4.2.Female (DGFCW2018022611): Total length 5.0; carapace length 3.5, width 2.1; abdomen length 4.4, width 2.6, height 2.6.O.grata; Fig. 1a, b, c, d, g) in which the CBP extends almost retrolaterally from the cymbium before curving distally; distinguished from males illustrated from further West in Southeast Asia (presumably true O.fastigata) by the length of the CBP, which is shorter and more gradually curved in O.sarawakensis of male palp projects initially posteriorly Fig. c, distinsis Fig. c than insis Fig. c, d, whisis Fig. d and O.yes Fig. c, which sis Fig. a, b, d a3.2-3.5; .Opadometasarawakensis is known from lowland dipterocarp forest in Bako National Park, Sarawak and Maliau Basin, Sabah, Malaysia ; no other Opadometa species were encountered. Opadometasarawakensis build open-hub webs with an inflection point so that the top half is more steeply inclined than the bottom half. The specific angles were quite different between the two webs measured have a female/male size ratio of 2.2, meaning the female is more than twice the total length of the male.Sexual size dimorphism in Opadometa, Opadometa they found in proximity to the red and blue Opadometa was conspecific. In light of the new data presented here, it appears that the male photographed in Koh and Ming (p. 260) is in fact O.sarawakensis.Given the troubled history of matching sexes in O.sarawakensis presented here is behavioral and faunistic (only one Opadometa species found in survey of orbweaving spiders). Another possible line of evidence would be DNA barcode sequences (Taxon Expeditions) is involved with field trials of the MinION, a portable DNA sequencer from Oxford Nanopore Technologies while O.fastigata is found further West, this should clear up some of the confusion regarding the distribution, sex matching, and anatomical features found in this genus.More work clearly needs to be done to sort out the distributions of the known"} +{"text": "Scientific Reports 10.1038/s41598-017-02596-1, published online 07 June 2017Correction to: In this Article, the author contributions section is incomplete:\u201cDr. Benito-Le\u00f3n (jbenitol67@gmail.com) collaborated in: (1) the conception, organization and execution of the research project; (2) the statistical analysis design, and; (3) and the writing of the manuscript first draft and the review and critique of the manuscript. Dr. Mato-Abad (virginia.mato@urjc.es) collaborated in: (1) the conception, organization of the research project; (2) the statistical analysis design; and (3) the review and critique of the manuscript. Dr. Louis collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Hern\u00e1ndez-Tamames (juanantonio.hernandez@ctb.upm.es) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. \u00c1lvarez-Linera collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Domingo-Santos (gela_yo@hotmail.com) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Luis Collado (lcollado@med.ucm.es) in: (1) the review and critique of the manuscript. Dr. Romero (juanpa5@hotmail.com) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript.\u201dshould read:\u201cDr. Benito-Le\u00f3n (jbenitol67@gmail.com) collaborated in: (1) the conception, organization and execution of the research project; (2) the statistical analysis design, and; (3) and the writing of the manuscript first draft and the review and critique of the manuscript. Dr. Mato-Abad (virginia.mato@urjc.es) collaborated in: (1) the conception, organization of the research project; (2) the statistical analysis design; and (3) the review and critique of the manuscript. Dr. Louis collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Hern\u00e1ndez-Tamames (juanantonio.hernandez@ctb.upm.es) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. \u00c1lvarez-Linera collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Bermejo-Pareja (fbermejop2013@yahoo.es) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Domingo-Santos (gela_yo@hotmail.com) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript. Dr. Luis Collado (lcollado@med.ucm.es) in: (1) the review and critique of the manuscript. Dr. Romero (juanpa5@hotmail.com) collaborated in: (1) the conception, organization of the research project; and (2) the review and critique of the manuscript.\u201d"} +{"text": "Correction to:Horticulture Research (2016) 3, 16017; doi:10.1038/hortres.2016.17; Published online 04 May 2016Since the publication of this article, the authors have noticed an error in In addition, the author Xiuxin Deng should be removed from the author list.The authors would like to apologize for this error."} +{"text": "Three references that were cited in fifth sentence of the fifth paragraph in the Discussion were omitted from the Reference section. The sentence is: The extensive literature on \u201cbargaining\u201d in economics was also more focused on the case in which players are in a symmetric position, and usually did not investigate proportional bargaining solutions.The references are:RAND Journal of Economics, 17(2), 176\u2013188. http://doi.org/10.2307/2555382Binmore, K., Rubinstein, A., & Wolinsky, A. (1986). The Nash bargaining solution in economic modelling. Rationality and Society, 23, 151\u2013173. Retrieved from http://rss.sagepub.com/content/10/3/275.shortBinmore, K. (1998). The evolution of fairness norms. Philosophy of Science, 67(3), 490\u2013516. http://doi.org/10.1086/392792Alexander, J. M. (2000). Evolutionary Explanations of Distributive Justice. A reference that was cited in the sixth sentence of the fifth paragraph in the Discussion was omitted from the References section. The sentence is: An exception is the work by Kalai (1977) , who shows that individuals will compromise in different bargaining situations so as to keep their proportions of utility gains fixed.Econometrica, 45(7), 1623\u20131630. http://doi.org/10.2307/1913954The reference is: Kalai, E. (1977). Proportional Solutions to Bargaining Situations: Interpersonal Utility Comparisons."} +{"text": "Scientific Data 3:160030 doi:10.1038/sdata.2016.30 (2016); Published 10 May 2016; Updated 31 Jan 2017The original version of this Data Descriptor contained a typographical error in the spelling of the author Douglas B. Rusch, which was incorrectly given as Douglas Rush. This has now been corrected in the PDF and HTML versions of the Data Descriptor."} +{"text": "A reference is omitted from the first sentence of the second paragraph under the heading \u201cPpr Localizes to Mitochondria and Its Loss Causes a Progressive Defect in ERGs\u201d in the Results section. The sentence should read:CG14786/Lrpprc2 (ppr) , which is required for the coordination of mitochondrial translation .The causative mutations of the five alleles of this complementation group were mapped to Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res. Dec 16;42(22):13920\u201338. doi: 10.1093/nar/gku1132. Epub 2014 Nov 26.The reference is: Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, et al. (2014)"} +{"text": "Across all these years, the Conference was chaired by Prof. Nikolay A. Kolchanov and Prof. Ralf Hofest\u00e4dt . In 2016, the multi-conference held parallel events and symposia on systems biology and biomedicine (SBioMed-2016) (http://conf.bionet.nsc.ru/ishg2016/en/), cognitive sciences (http://physiol.ru/csgb2016/), and mathematical modeling in biology (MM-HPC-BBB-2016) (http://conf.bionet.nsc.ru/mm-hpc-bbb-2016/en/). Since 2014, the BGRS Program Committee has collaborated with BioMed Central on full-text thematic issues reflecting the main science achievements of the conference series in past years. Recently BioMed Central had published several special issues based on best materials presented at the conference in BMC Genetics [http://bmcgenet.biomedcentral.com/articles/supplements/volume-16-supplement-1), BMC Genomics , BMC Evolutionary Biology , and BMC Systems biology .This special issue continues the series of BioMed Central special post-conference journal issues . All these issues collate the papers presented at BGRS\\SB-2016, 10th International Conference \u201cBioinformatics of Genome Regulation and Structure\\Systems Biology\u201d which took place at August 29 - September 2, 2016 in Novosibirsk, Russia. The BGRS conference series started in 1998 in Novosibirsk Akademgorodok in the tumour suppressor APC gene. It was shown that both putative promoters of APC (1A and 1B) drive transcription in an in vitro reporter experiment, many SNPs are functionally relevant and allele G of rs79896135 may be associated with the predisposition to colorectal cancer [The article by Kudryavtseva et al. highlights molecular mechanism of hexokinases function in tumorigenesis of human colorectal cancer and melanoma. The authors studied the effect of silencing hexokinase genes in colorectal cancer and melanoma cells using short hairpin RNA (shRNA) lentiviral vectors suggesting the HK1 and HK2 genes as the key therapeutic targets for reducing aerobic glycolysis .Two papers by Korbolina et al. and RyazThe paper by Elena Korbolina and colleagues describeThe ISIAH rat strain was developed by selection for high systolic arterial blood pressure (SABP) induced by restraint stress. Earlier studies showed that the ISIAH rats may be considered as a model of the human stress sensitive hypertensive disease with predominant involvement of the neuroendocrine hypothalamic-pituitary-adrenal (HPA) and sympathoadrenal systems in the pathogenesis of the hypertensive state .The studDendrolimus (Lepidoptera: Lasiocampidae), which are among the major pests of coniferous forests worldwide. The study clarifies the taxonomy of the moths of this genus in Eurasia using mitochondrial markers.The paper by A. Kononov et al. highlighFinally, the work by P. Drozdova et al. discussehttp://www.bionet.nsc.ru/files/2016/conference/BGRS2016.pdf.All BGRS\\SB-2016 Proceedings including \u201cBioinformatics and Systems Biology of Plants\u201d section are available at the multi-conference web-site: http://www.worldscientific.com/toc/jbcb/13/01) [http://vavilov.elpub.ru/jour/issue/view/15/showToc) (in Russian).Additionally, special issues on bioinformatics were published at the Journal of Bioinformatics and Computational Biology (http://conf.bionet.nsc.ru/sbb2016/en/) and Open Russian-German workshop on bioinformatics network \u201cSystems computational biology\u201d.As usual, BGRS/SB-2016 was accompanied by a number of satellite events, including already traditional Young Scientists School \u201cSystems Biology and Bioinformatics\u201d (SBB-2016) ("} +{"text": "The publisher apologizes for the error. The correct citation should be as follows: Gradidge PJ, Norris SA, Jaff NG, Crowther NJ (2016) Metabolic and Body Composition Risk Factors Associated with Metabolic Syndrome in a Cohort of Women with a High Prevalence of Cardiometabolic Disease. PLoS ONE 11(9): e0162247. doi:"} +{"text": "In the Author Contributions section, it should be noted that Norma-Rashid Yusoff also contributed to Supervision.The Funding section is incomplete. The complete funding information is: This work was supported by Malaysian Forest Research and Development Board (Grant number: GPP-0609-FA-02) received by CK; Postgraduate Research Fund from University of Malaya (Grant number: PV131/2012A) received by NY; Malaysian Economic Planning Unit and Ministry of Natural Resources and Environment, Malaysia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Trogonoptera brookiana albescens). PLoS ONE 12(12): e0189450. https://doi.org/10.1371/journal.pone.0189450The abbreviation for the third author is incorrect in the citation. The correct citation is: Phon C-K, Kirton LG, Norma-Rashid, Y (2017) Monitoring butterflies using counts of puddling males: A case study of the Rajah Brooke\u2019s Birdwing (10.5176/2251-3353_GEOS14.37.There is an error in the URL link for Reference 9. The correct reference is: Baioumy HM, Nawawi M, Wagner K, Arifin MH. Geological setting and origin of non-volcanic hot springs in West Malaysia. GEOS 2014: Proceedings of the 3rd International Conference on Geological and Earth Sciences; Singapore. 2014. pp. 14\u201318. doi:The publisher apologizes for these errors."} +{"text": "The supporting information tables incorrectly include tracked changes that make them illegible. Please view the correct S1 Tabler-values obtained with Polar Plot analysis in individual rats and in groups of intact, saline and Riluzole treated animals. The values of SEM ranged from 0.64 to 1.99%. Abbreviations: L/Co-left/control, R/SNC-right-muscle with SNC, Sol-soleus, EDL-extensor digitorum longus. Abbreviations for statistical significance vs intact rats: *\u2014p < 0.001.The table contains mean (\u00b1 circular SD) of phase shifts of intralimb (L/Co Sol\u2014L/Co EDL and R/SNC Sol\u2014R/SNC EDL) and interlimb (R/SNC Sol\u2014L/Co Sol and R/SNC EDL\u2014L/Co EDL) coordination and (DOC)Click here for additional data file.S2 TableThe table contains mean (\u00b1SD) of cycle durations established based on the left and right Sol and EDL muscles, on control muscles and muscles with SNC in individual rats and in groups of intact, saline and Riluzole treated animals. The values of SEM ranged from 1.78 to 3.20%. Abbreviations: L/Co-left/control, R/SNC-right/muscle with SNC.(DOC)Click here for additional data file.S3 Tablep for significance of intercepts and correlation coefficients r in individual intact, saline and Riluzole treated animals. The values of p or significance of slopes and correlation coefficients were < 0.001 in all instances. Abbreviations: L/Co-left/control, R/SNC-right/muscle with SNC.The table contains slopes and intercepts of regression with the values of (DOC)Click here for additional data file.S4 Tablep for their significance as well as correlation coefficients r in individual intact, saline and Riluzole treated animals. Abbreviations: L/Co-left/control, R/SNC-right/muscle with SNC.The table contains slopes and intercepts of regression with the values of (DOC)Click here for additional data file.S5 Tablep < 0.011.The table contains mean (\u00b1SD) cycle duration, burst duration and duty factor in individual rats and in groups of intact, saline and Riluzole treated animals. The values of SEM ranged from 0.71 to 1.67%. Abbreviations: L/Co-left/control, R/SNC-right/muscle with SNC. Abbreviations for statistical significance vs intact rats: *\u2014(DOC)Click here for additional data file.S6 Tablep < 0.001.The table contains mean (\u00b1SD) cycle duration, burst duration and duty factor in individual rats and in groups of intact, saline and Riluzole treated animals. The values of SEM ranged from 0.57 to 3.96%. Abbreviations: L/Co-left/control, R/SNC-right/muscle with SNC. Abbreviations for statistical significance vs intact rats: *\u2014(DOC)Click here for additional data file.S7 Tabler with corresponding values of p for significance, for the relationship between the duty factor of burst of EMG activity of right muscle/muscle with SNC and the duty factor of burst of EMG activity of left muscle/control muscle for the Sol and EDL muscles in individual intact rats, saline and Riluzole treated animals. In addition the table contains the values of common correlation coefficients rw with the values of pw obtained with a test for the heterogeneity of correlation coefficients in the respective groups. Abbreviations: DF-duty factor, Sol-soleus, EDL-extensor digitorum longus.The table contains correlation coefficients (DOC)Click here for additional data file.S8 Tabler with the values of p obtained in individual rats and in group of intact rats for the left muscles as well as in individual rats and in groups of saline and Riluzole treated animals for the control muscles. The values of SEM ranged from 1.19 to 3.83%. Abbreviations for statistical significance vs intact rats: *\u2014p < 0.001.The table contains mean (\u00b1SD) of interval durations, predicted durations, slopes and intercepts of regressions as well as correlation coefficients (DOC)Click here for additional data file.S9 Tabler with the values of p obtained in individual rats and in group of intact rats for the right muscles as well as in individual rats and in groups of saline and Riluzole treated animals for muscles with SNC. The values of SEM ranged from 1.19 to 3.83%. Abbreviations for statistical significance vs intact rats: *\u2014p < 0.001.The table contains mean (\u00b1SD) of interval durations, predicted durations, slopes and intercepts of regressions as well as correlation coefficients (DOC)Click here for additional data file."} +{"text": "Owing to errors made by SAGE, the following article contains errors.Christoph Witzel (September-October 2016). An Easy Way to Show Memory Color Effects.10.1177/2041669516663751).i-Perception, 7(5), 1\u201311. (DOI: SAGE apologises to the author and to the readers. The following corrections apply:These corrections will be included in all subsequent versions of the article online."} +{"text": "Scientific Data 4:170179 doi: 10.1038/sdata.2017.179 (2017); Published 19 December 2017; Updated: 23 January 2018.In both the HTML and PDF versions of this Data Descriptor, the author name Jason Flannick was incorrectly listed as Flannick Jason."} +{"text": "Abstractspecies distribution modelling (SDM) and for model testing in a poorly documented marine region.The present dataset provides a case study for Echinodermata: Echinoidea) distribution. Echinoids were collected during oceanographic campaigns led around the Kerguelen Plateau since 1872. In addition to the identification of collection specimens from historical cruises, original data from the recent campaigns POKER II (2010) and PROTEKER 2 to 4 (2013-2015) are also provided. In total, five families, ten genera, and 12 echinoid species are recorded in the region of the Kerguelen Plateau.The dataset includes spatially-explicit data for echinoid .Future projections are provided for several parameters: they were modified from the Bio-ORACLE database . They arPageBreak Project title: Temporal, spatial, and sampling heterogeneities in species distribution modelling. A case study for the data-poor area of the Kerguelen Plateau.Personnel: Charl\u00e8ne Guillaumot, Alexis Martin, Salom\u00e9 Fabri-Ruiz, Marc El\u00e9aume, Thomas Sauc\u00e8deFunding: This study is part of a project funded by CNRS laboratory UMR6282 Biogeosciences and by the vERSO program . This is contribution no.14 to the vERSO project (www.versoproject.be), funded by the Belgian Science Policy Office . This is a contribution to the POKER program and the (Institut polaire fran\u00e7ais Paul-Emile Victor)IPEV program 1044 PROTEKER.6 km2 CCAMLR and by the (French Southern and Antarctic Lands)TAAF in the French (Exclusive Economic Zone)EEZ with scientific support from the Mus\u00e9um national d\u2019Histoire naturelle of Paris since 1978 Marine Protected Area: one of the world\u2019s largest MPA with an area of 65,000 km2 led in nearshore areas of the Kerguelen Islands. The spatial extent of the dataset was based on the bathymetric range of echinoids for species distribution modelling to be performed with limited extrapolations.In addition to the study of collection specimens sampled during historical cruises and identified at species level, the present work also provides original data collected during the recent oceanographic campaign POKER II (2010) and during three field summer campaigns of the Our project aimed at improving the robustness of existing modelling approaches in the case of areas for which only poor and heterogeneous biodiversity data are available, a situation prevailing in the region of the Kerguelen Plateau, and generally in the Southern Ocean .Data compilation from various sources implies temporal heterogeneities that may constitute a critical point when building species distribution models . SpatialOccurrence data were compiled from many oceanographic campaigns led over a long time-period starting with the Challenger Expedition in 1872 and ending with the recent PROTEKER campaigns that took place between 2013 and 2015 Table a. SpecimPageBreakPageBreakOccurrences are presence-only data for which different sampling tools, protocols, and strategies were used. Moreover, the study area was unevenly investigated, sampling effort being stronger in the northern than in the southern part of the Plateau Figure . AccordiThe environmental descriptors provided in the dataset were compiled from different sources and raw depth values measured in the field and mean winter (July to September) surface and seafloor temperatures and salinities) are available for the following six decades: 1955 to 1964, 1965 to 1974, 1975 to 1984, 1985 to 1994, 1995 to 2004, and 2005 to 2014.th IPCC report (2007). The modelled data correspond to the extrapolated means for two decades: 2087-2096 (here referred to as 2100) and 2187-2196 (here referred to as 2200) .All the environmental descriptors and metadata sources are detailed in the data catalog Table and dataSpecimens sampled during POKER II and PROTEKER 2, 3 and 4 campaigns were all identified by T. Sauc\u00e8de at the species level. Identifications and taxonomic accuracies are based on The final compiled dataset was checked for consistency using the WoRMS database in orderEnvironmental data relies on different sources as reported in Table Echinoidea (Echinodermata) occurring on the Kerguelen Plateau.The present dataset focuses on all species of the class PageBreakPageBreakPageBreakPageBreakEchinoids are common species of benthic communities in the Southern Ocean and on the Kerguelen Plateau . They arCtenocidarisnutrix is considered a Vulnerable Marine Ecosystems (VME) indicator species by (Commission for the Conservation of Antarctic Marine Living Resources)CCAMLR and is widely distributed on the Kerguelen Plateau.Echinoid studies take part in conservation issues. Echinoidea includes five families, ten genera, and 12 species. Species distribution is shown in Figure On the Kerguelen Plateau, the Class Phylum: EchinodermataClass: EchinoideaOrder: Camarodonta, Cidaroida, Holasteroida, SpatangoidaFamily: Ctenocidarinae, Echinidae, Plexechinidae, Pourtalesiidae, SchizasteridaeGenus: Abatus, Aporocidaris, Brisaster, Ctenocidaris, Dermechinus, Plexechinus, Pourtalesia, Rhynchocidaris, Sterechinus, TripylusSpecies: Abatuscordatus, Aporocidarismilleri, Brisasterantarcticus, Ctenocidarisnutrix, Dermechinushorridus, Plexechinussulcatus, Pourtalesiahispida, Pourtalesiadebilis, Rhynchocidaristriplopora, Sterechinusdiadema, Sterechinusneumayeri, TripylusabatoidesGeneral spatial coverage: the Kerguelen Plateau, Southern OceanCoordinates: -46\u00b0S and -56\u00b0S; +63\u00b0E and +81\u00b0ETemporal coverage: 1872\u20132015Echinoid occurrences available on the Kerguelen Plateau. Data from 1872 to 2015 collected with different sampling strategies and objectives, during different campaigns.Object name: Echinoids_Kerguelen_Plateau_1872_2015PageBreakCharacter encoding: x-MacRomanFormat name: Darwin Core Archive FormatFormat version: 3.0Distribution: http://ipt.biodiversity.aq/resource.do?r=echinoids_kerguelen_plateau_18- 72_2015Publication date of data: 12/07/2016Language: EnglishMetadata language: EnglishDate of metadata creation: 12/07/2016Hierarchy level: DatasetPageBreakand seafloor temperature, salinity and their respective amplitude data are available on the time coverage 1955-2012 and over six decades: 1955 to 1964, 1965 to 1974, 1975 to 1984, 1985 to 1994 and 1995 to 2004, and 2005 to 2012.Environmental variables in the region of the Kerguelen Plateau compiled from different sources and provided in the ascii raster format . Mean suth report).Future projections are provided for several parameters: they were modified after the Bio-ORACLE database . They arObject name: Environmental_Kerguelen_Plateau_1955_2012Format name: RasterFormat version: 1.0Distribution: https://data.aad.gov.au/metadata/records/Environmental_Kerguelen_Plateau_1955_2012doi: 10.4225/15/578ED5A08050FPublication date of data: 16/07/2016Language: EnglishMetadata language: EnglishDate of metadata creation: 16/07/2016Hierarchy level: Dataset"} +{"text": "The name and citation appear correctly in the PDF version.The fifth author\u2019s name is spelled incorrectly in the online version. The correct name is J. Frank Wharam. The correct citation is: Lopez Bernal JA, Lu CY, Gasparrini A, Cummins S, Wharam JF, Soumerai SB (2017) Association between the 2012 Health and Social Care Act and specialist visits and hospitalisations in England: A controlled interrupted time series analysis. PLoS Med 14(11): e1002427."} +{"text": "There are multiple errors in the manuscript.There is an error in reference 65. The correct reference is: \u201cSpeir M, Lawlor KE, Glaser SP, Abraham G, Chow S, Vogrin A, et al. Nat Microbiol. 2016 Feb 24;1:15034. doi: 10.1038/nmicrobiol.2015.34.\u201dThe following information is missing from the Funding section: \u201cResearch reported in this publication was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number P20GM103652.\u201d"} +{"text": "Correction to:European Journal of Clinical Nutrition (2017); 71 (1); 51-55; doi: 10.1038/ejcn.2016.166; published online 14th September 2016Since the publication of the article, the authors have noticed an error in The authors apologise for any inconvenience caused by this error."} +{"text": "Nature Communications7: Article number: 13045; DOI: 10.1038/ncomms13045 (2016); Published: 10102016; Updated: 06142017This Article contains an error in Fig. 8a, for which we apologize. In Fig. 8a, the control 3 image for p-ERK staining was inadvertently duplicated from the control 1 image of p-ERK staining. The correct version of this figure appears below as"} +{"text": "In the Funding section, the grant number from EPSRC MOTION is listed incorrectly. The correct grant number is: EP/N03211X/2.There is an error in affiliation 4 for author Thrishantha Nanayakkara. Affiliation 4 should be: Dyson School of Design Engineering, Imperial College London, South Kensington Campus, London, United Kingdom."} +{"text": "CDC is assisting ministries of health and working with other organizations to control and end the ongoing outbreak of Ebola virus disease (Ebola) in West Africa . The updAccording to the latest World Health Organization update as of October 22, 2014 . The higThe geographic distribution of the number of Ebola cases reported during September 28\u2013October 18 changed from the distribution of cases reported during August 31\u2013September 23 .The map of the cumulative incidence of Ebola, as of October 18, indicates that the highest incidence rate was reported by two districts in Guinea (Gu\u00e9ck\u00e9dou and Macenta), five districts in Liberia , and four districts in Sierra Leone .http://www.cdc.gov/vhf/ebola/outbreaks/guinea/index.html. The most up-to-date clinical guidelines on the 2014 Ebola outbreak in West Africa are available at http://www.cdc.gov/vhf/ebola/hcp/index.html.The latest updates on the 2014 Ebola outbreak in West Africa, including case counts, are available at"} +{"text": "The publisher apologizes for the error.The fourth author\u2019s name is spelled incorrectly. The correct name is: Leila Sissani. The sixth author\u2019s name is spelled incorrectly. The correct name is: Saverio Stranges. The correct citation is: Sauvageot N, Leite S, Alkerwi A, Sissani L, Zannad F, Stranges S, et al. (2016) Association of Empirically Derived Dietary Patterns with Cardiovascular Risk Factors: A Comparison of PCA and RRR Methods. PLoS ONE 11(8): e0161298. doi:"} +{"text": "Correction to: British Journal of Cancer (2009) 101, 916\u2013923; doi:10.1038/sj.bjc.6605262After publication of the above paper in Volume 101, Number 6, the authors realised that they had intended to include an Acknowledgements paragraph in the article. The paragraph should read as follows:"} +{"text": "After the publication of this work , we becaIn the method section, see following paragraph: \"In the present study all assessments of hip abduction, hip external rotation, popliteal angle, knee extension and dorsiflexion of the foot with knee flexion from the start 1994 until 1 January 2007 were included (Table 2).\"In Table 2. Goniometer positioning and standardization procedure for all five joint angles, Extremity position Foot dorsiflexion. Supine. Knee in flexion.The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1741-7015/8/49/prepub"} +{"text": "Correction to: British Journal of Cancer (2002) 87, 630\u2013634. doi:10.1038/sj.bjc.6600511 Unfortunately due to a typesetting error, Figure 2The correct version is reprinted below:The publisher would like to apologise for any inconvenience this may have caused."} +{"text": "Correction to: British Journal of Cancer (2009) 100, 1926\u20131936; doi:10.1038/sj.bjc.6605072In reference to"} +{"text": "A focal H5N1 outbreak in poultry was reported from Manipur, a north-eastern state, of India, in 2007. The aim of this study was to genetically characterize the Manipur isolate to understand the relationship with other H5N1 isolates and to trace the possible source of introduction of the virus into the country.Characterization of the complete genome revealed that the virus belonged to clade 2.2. It was distinctly different from viruses of the three EMA sublineages of clade 2.2 but related to isolates from wild migratory waterfowl from Russia, China and Mongolia. The HA gene, had the cleavage site GERRRRKR, earlier reported in whooper swan isolates from Mongolia in 2005. A stop codon at position 29 in the PB1-F2 protein could have implications on the replication efficiency. The acquisition of polymorphisms as seen in recent isolates of 2005\u201307 from distinct geographical regions suggests the possibility of transportation of H5N1 viruses through migratory birds.Considering that all eight genes of the earlier Indian isolates belonged to the EMA3 sublineage and similar strains have not been reported from neighbouring countries of the subcontinent, it appears that the virus may have been introduced independently. Highly pathogenic avian influenza (HPAI) A \u2013 H5N1 viruses have now appeared in about 60 countries causing devastating outbreaks in poultry with continued capacity to impact humans . The HonThe first outbreak of the H5N1 virus in India was reported from Maharashtra in January 2006 . Seven eThe aim of this study was to genetically characterize the Manipur isolate of 2007 to understand the relationship with other H5N1 isolates and to trace the possible source of introduction of the virus into the country.The state of Manipur (latitude 23\u00b083'N \u2013 25\u00b068'N and longitude 93\u00b003'E \u2013 94\u00b078'E) is known for some animal sanctuaries that are home to many exotic flora and fauna Figure . A largeSix clinical samples from different organs of a sick bird were received from Manipur. Specimens were processed for virus isolation in specific-pathogen-free (SPF) embryonated chicken eggs and Madin Darby Canine Kidney (MDCK) cell lines as described earlier . InoculaHemagglutination (HA) and Hemagglutination inhibition (HAI) tests were performed as described by Kendal et al. . Horse RRNA was extracted using QIAamp Viral RNA Minikit following manufacturers instruction. One-Step reverse transcription-PCR (RT-PCR) was performed using the QIAGEN one-step RT-PCR kit and WHO recommended diagnostic primer sets specific for influenza A HA (H5) and NA (N1) genes . RNA isoRNA isolated from the specimens was reverse transcribed as mentioned earlier . cDNA waFor phylogenetic analysis, representative sequences of the H5N1 viruses belonging to the Z genotype were selected from the GenBank based on sequence identity and geographical representation. In this process of selection, the sequences whose whole genome was available were preferred. Phylogenetic analysis was performed using the Bayesian approach for tree construction as implemented in Mr Bayes 3.2 . The GTRFJ719831\u2013FJ719838. The percent nucleotide identity (PNI) and percent amino acid identity (PAI) values were calculated as pairwise p-distances, for a dataset of about 80 representative sequences in each gene. For clarity, limited representative sequences are shown in the phylogenetic trees virus in HA and HAI.Samples tested in one step RT-PCR showed amplification of influenza A, H5 and N1 gene specific bands. A 219 base pair band appeared showing presence of H5 and 668 base pair for the presence of N1. Real Time RT-PCR analysis showed the presence of Avian influenza (H5N1) in all the specimens (Data not shown).Phylogenetic analysis of 41 whole genomes, all the eight gene segments concatenated, showed that the Manipur isolate was unique in the clade 2.2, as it did not cluster with the majority of the isolates in the EMA sublineages 1 to 3 with the A/Gf/Shantou/1341/06 isolate, followed by the A/Dk/Novosibirsk/56/05 and the A/Ck/Omsk/14/05 isolates with 98.99 PNI and 9 amino acid differences in all the three cases. It showed closest amino acid identity of 98.95 (8 differences) with several isolates including A/Ck/Egypt/22531/06, A/Sw/Slovenia/760/06, A/Ck/Gaza/714/06, A/Pg/Denmark/6632/06, A/Tk/Turkey/1/05 and A/Co/Croatia/1/05. In case of the PB1 gene, the Manipur isolate was closest in PNI (98.95) to the A/Ck/Kurgan/3/05 isolate with also the highest amino acid identity . The PA gene of the Manipur isolate had closest PNI (98.83) with the A/BHGs/Qinghai/59/05 isolate, followed by Azerbaijan/002115/06 with 7 amino acid differences. The closest PAI (99.16) with 6 amino acid differences was with the A/Ck/India/NIV33487/06 isolate (PNI 98.65). The Novosibirsk/05, Liaoning/05 and Mongolia/06 and Iran/06 showed PAI of 98.89 (7 aa differences) but higher PNI (98.7).The NP gene showed closest PNI with the A/Gs/Hungary/3413/07 isolate (98.9) and 1 amino acid difference. The closest PAI (99.79) also amounting to a single amino acid difference was with several isolates including the A/Tk/England/250/07, A/Gs/Qinghai/F/06, A/Md/Bavaria/1/06, A/Turkey/15/06, A/Krasnoozerskoe/627/05, A/Omsk/14/05, A/Dk/Novosibirsk/02/05, A/Ck/Kurgan/3/05, and A/Ws/Mongolia/3/05. The M gene shared the highest PNI (98.81) with the A/Dk/Novosibirsk/56/05 isolate. The NS gene had highest PNI with A/Dk/Novosibirsk/05 and A/Suzdalka/10/05 (98.96) followed by the A/BHGs/Qinghai/F/06 isolate (98.9). Again, in all these genes the Manipur isolate was distinct from the others and also did not cluster with any of the EMA sublineages.AB233320\u2013AB233322). Subsequently, the same pattern was noted in several isolates of 2007 from Egypt and Nigeria (EU148396). Another non synonymous mutation, S155N, at the N154 glycosylation site, observed in the Manipur isolate was also noted in the 2005 isolates of Novosibirsk, Qinghai, Tambov, Crimea, Omsk, Suzdalka, and Liaoning and majority of the EMA1 isolates. D54N in the Manipur isolate was shared with the A/Ck/Egypt/1079NAMRU3/07 isolate and the A/Ws/Mongolia/4/05 isolate. One unique mutation L297F in the Manipur isolate was not noted in any of the clade 2.2 isolates but was observed in A/Dk/HongKong/ww381/2000. T513A mutation was shared with A/Ck/Krasnador/199/06. Among synonymous nucleotide substitutions in the Manipur isolate, G42A, G705A, T861C, 983G, A1632G were shared with the Egypt/07 and/or Nigeria/07 isolates; T78C with A/Tk/SaudiArabia/67326/07; T573C with A/Gf/Shantou/1341/06, A/Pm/Liaoning/7/05 and A/Tk/CzechRep/10309-3/07; C1335T with A/Dk/Novosibirsk/56/05 and A/Ck/Sudan/21159/06.In the HA gene, among amino acid mutations, the Manipur isolate had a substitution K328R . This corresponds to the novel HA cleavage site, GERRRRKR that was originally found in three whooper swan isolates of Mongolia in 2005 viruses isolated in Europe, the Middle-Eastern region and Africa beyond 2005 . A minorThe molecular characterization of the viral proteins of the Manipur isolate was carried out for pathogenicity markers and sensitivity to antivirals. The HA of the Manipur isolate had the novel cleavage site (GERRRRKR) that was first reported in three whooper swan isolates in Mongolia, 2005 and also in the recent Nigeria/07 and Egypt/07 isolates. Though variations in the cleavage site such as RERRRKKR, RERRKKR and RERRRR have been linked to human H5N1 cases , no suchThe phylogenetic characterization of the Manipur isolate demonstrated that the virus isolated in 2007 in India was distinctly different from the viruses of the three EMA sublineages. Considering that all the eight genes of the 2006 isolates of India belonged to the EMA3 sublineage, with several mutations observed between the two strains, the possibility of local evolution can be excluded. Genetic analysis of the Manipur 2007 isolate clearly indicates a second introduction of the H5N1 virus in India. Among the other isolates that have been placed outside the EMA groups, the Manipur isolate was distinct and unique. It was related to viruses isolated from wild migratory waterfowl from Russia , China and Mongolia. A recent report stated tOverall, our findings suggest that the Manipur 2007 virus isolate is a unique variant and not related to the 2006 Indian isolate. The introduction of such a virus, either directly or indirectly, into India calls for improved surveillance in the country and subcontinent. The appearance of such variants is also serious concern for the emergence of even more highly pathogenic strains and a pandemic threat.BHGs: Bar headed goose; Ck: Chicken; Co: Cygnus olor; Dk: Duck; Gf: Guinea fowl; Gs: Goose; Md: Mallard; Pg: Peregrine; PgFc: Peregrine falcon; Pm: Piedmagpie; Sw: swan; Tk: Turkey; Ws: Whooper swan.The authors declare that they have no competing interests.ACM, AKC and SDP conceived and designed the experiments. AKC, SDP, BP, SR, SK and SSK performed the experiments, SSC, SMJ and AKC planned and performed the bioinformatics studies, SSC, AKC, SMJ and ACM analyzed the data, SSC, AKC and ACM wrote the paper. All authors read and approved the final manuscript."} +{"text": "Correction to: British Journal of Cancer (2006) 94, 1079\u20131085. doi:10.1038/sj.bjc.6603031Owing to an author error, the data presented in"} +{"text": "This report documents the additions and revisions to the nomenclature of HLA specificities following the principles established in previous reports methodology, where both alleles of a heterozygous individual are sequenced together, is insufficient evidence for assignment of an official designation.Sequence derived solely from the primers used to amplify an allele must not be included in the submitted sequence.Where possible, a novel sequence should be confirmed by typing of genomic DNA using a method such as PCR-SSOP or PCR-SSP. Where a new sequence contains either a novel mutation or a previously unseen combination of nucleotides (sequence motif), this must be confirmed by a DNA typing technique. This may require the use of newly designed probes or primers to cover the new mutation; these reagents should also be described.An accession number in a databank should have been obtained. Sequences may be submitted to the databases online at the following addresses:www.ebi.ac.uk/Submissions/index.htmlEMBL: www.ncbi.nlm.nih.gov/Genbank/submit.htmlGenBank: www.ddbj.nig.ac.jp/sub-e.htmlDDBJ: Full-length sequences are preferable though not essential; the minimum requirements are complete exons 2 and 3 for an HLA class I sequence and complete exon 2 for an HLA class II sequence.Where a novel sequence differs only within an intron or other non-coding part of the gene, a full-length sequence must be obtained, which covers all coding and non-coding regions. In the absence of a full-length genomic sequence from the most closely related allele that is identical in its exon sequence, it may be required that this also be sequenced and submitted before a name can be assigned to the novel sequence.Where possible, a paper in which the new sequence is described should be submitted for publication. Copies of draft publications can be submitted to the database by email or FAX.Sequences derived solely from tumour material will not be considered for nomenclature.HLA-A, -B and -DRB1 genes should be submitted for the material in which a novel allele has been defined. In addition the sample should have been characterised for the second allele at the locus of interest in a heterozygous individual.The complete HLA type for the DNA or other material, preferably cell lines, should, wherever possible, be made available in a publicly accessible repository or alternatively, at least in the originating laboratory. The WHO Nomenclature Committee will maintain documentation on this material.www.ebi.ac.uk/imgt/hla/subs/submit.html. Researchers are expected to complete a questionnaire relating to the sequence and provide a comparison of their new sequence with known related alleles. If the sequence cannot be submitted using the online web tools, researchers should contact hla@alleles.org directly for details of alternative submission methods.Submission of a sequence to the WHO Nomenclature Committee should be performed using the online submission tool available at Although at present it is only a recommendation that full-length sequences of the coding region of novel alleles be submitted it was widely felt that in the future this should become a requirement for submission. Such requirement would remove many of the currently encountered ambiguities in the assignment of names to alleles for which partial sequences have been submitted and should not be burdensome as sequencing techniques have improved substantially since the submission conditions were first devised. In cases where novel mutations or polymorphisms are detected in non-coding regions of the gene, it will be a requirement that full-length sequences be submitted of both the novel allele and its most closely related allele.It should be noted with some caution that cells from which only partial sequences have been obtained may later be shown to have different or novel alleles when further sequencing is performed. This is of particular importance in cases where partial sequences of what appears to be the same allele have been obtained from several different cells. In such cases, all cells studied have been listed in this report.Current practice is that official designations will be promptly assigned to newly described alleles in periods between Nomenclature Committee meetings, provided that the submitted data and its accompanying description meet the criteria outlined above. A list of the newly reported alleles is published each month in nomenclature updates in the journals Tissue Antigens, Human Immunology and the International Journal of Immunogenetics. The listing of references to new sequences does not imply priority of publication. The use of numbers or names for alleles, genes or specificities which pre-empt assignment of official designations by the Nomenclature Committee is strongly discouraged.The list of those genes in the HLA region considered by the WHO Nomenclature Committee is given in b. New Allele SequencesHLA-A, 913 HLA-B, 446 HLA-C, four HLA-E, 19 HLA-F, 31 HLA-G, 12 HLA-H, nine HLA-J, six HLA-K, five HLA-L, four HLA-P and three HLA-V alleles were named, making a total of 3249 class I alleles with official names. For HLA class II, 368 HLA-DRB1, 12 HLA-DRB3, one HLA-DRB4, one HLA-DRB5, seven HLA-DQA1, 45 HLA-DQB1, six HLA-DPA1, 22 HLA-DPB1, one HLA-DMB and four HLA-DOA alleles were named, making a total of 1198 class II alleles with official names. Eleven MICA alleles were named bringing their total to 68 and 12 MICB alleles bringing their total to 30 alleles, see st December 2009 is given in A total of 2558 HLA alleles have been named since the last report A*30:14L was named. The allele has a mutation in codon 164 encoding a cysteine residue contributing to a structurally critical disulphide bond in the \u03b12 domain of the HLA molecule. Expression studies performed on cells with this allele showed its protein to have a much-reduced expression compared to normal, and the allele name was thus given the suffix \u2018L\u2019 to indicate this low expression. Since then several other alleles have been reported that have also lost one of the two cysteine residues (position 101 and 164) that form the \u03b12 domain disulphide bond. It has not, however, been possible to ascertain the expression status of these alleles, due to a lack of viable material. The Nomenclature Committee considered the naming of these alleles during the 14th HLA and Immunogenetics Workshop. As a result of these discussions, it was decided to introduce an additional suffix, Q, to indicate a \u2018Questionable\u2019 expression level. The first seven alleles to receive this suffix have been named and are included in this report, A*23:19Q, A*32:11Q, B*13:08Q, B*35:65Q, B*39:38Q, C*02:25Q and C*03:22Q. It is anticipated that when further examples of these alleles are described, their expression status will be determined and the suffix changed accordingly.In February 2005 the allele HLA-DRB1*03, *11, *13, *14 and *08 family of alleles, for which the description of new alleles has revealed a continuum of allelic diversity rather than five discrete sub-families. It should be stressed that, although a goal is to indicate the serological grouping into which an allele will fall, this is not always possible. Most importantly the allele name should be seen as no more than a unique designation.As the database of HLA allele sequences has expanded, it has become increasingly difficult to maintain consistent linkage between allele names assigned on the basis of nucleotide sequences and the serological profiles of the encoded proteins. These difficulties are in part technological and in part due to the inherent biological properties of the HLA system. In the first category there is the increasing emphasis on DNA technology and consequent lack of a serological description for many newly discovered HLA alleles. In the second category is the finding that a newly defined antigen does not comfortably fit within any known serological grouping. This is especially true of the th International HLA and Immunogenetics Workshop in 2005 having been clearly identified as a novel antigen in a number of UCLA cell exchanges.Where this information is known, lists of the serological specificities or antigens associated with the alleles, is given in The convention of using a four-digit code to distinguish HLA alleles that differ in the proteins they encode was introduced in the 1987 Nomenclature Report The first two digits describe the allele family, which often corresponds to the serological antigen carried by the allotype. The third and fourth digits are assigned in the order in which the sequences have been determined. Alleles whose numbers differ in the first four digits must differ by one or more nucleotide substitutions that change the amino-acid sequence of the encoded protein. Alleles that differ only by synonymous nucleotide substitutions within the coding sequence are distinguished by the use of the fifth and sixth digits. Alleles that only differ by sequence polymorphisms in introns or in the 5\u2032 and 3\u2032 untranslated regions that flank the exons and introns are distinguished by the use of the seventh and eight digits.A*02 and B*15 allele families having more than 100 alleles A*92 and B*95 respectively. For HLA-DPB1 alleles, it was decided to assign new alleles within the existing system, hence once DPB1*9901 had been assigned, the next allele would be assigned DPB1*0102, followed by DPB1*0203, DPB1*0302 etc.In 2002 we faced the issue of the When these conventions were adopted it was anticipated that the nomenclature system would accommodate all the HLA alleles likely to be sequenced. Unfortunately this is not the case, as the number of alleles for certain genes is fast approaching the maximum possible with the current naming convention.With the ever increasing number of HLA alleles described it has been decided to introduce colons (:) into the allele names to act as delimiters of the separate fields. To facilitate the transition from the old to the new nomenclature, a single leading zero must be added to all fields containing the values 1 to 9 but beyond that no leading zeros are allowed. This will help to lessen any confusion in the conversion to the new style of nomenclature.HenceA*01010101 becomes A*01:01:01:01A*02010102L becomes A*02:01:01:02LA*260101 becomes A*26:01:01A*3301 becomes A*33:01B*0808N becomes B*08:08NDRB1*01010101 becomes DRB1*01:01:01:01A*02 and B*15 groups it will be possible to encode these in a single series. Thus the A*92 and B*95 alleles have now been renamed in to the A*02 and B*15 allele series. For example:For allele families that have more than 100 alleles such as the A*9201 becomes A*02:101A*9202 becomes A*02:102A*9203 becomes A*02:103 etcB*9501 becomes B*15:101B*9502 becomes B*15:102B*9503 becomes B*15:103 etcA*02:100 and B*15:100 will not be assigned. In cases of other allele families where the number of alleles reaches 100 these will be numbered sequentially, for example A*24:99 will be followed by A*24:100.The names DPB1 allele names that have been previously assigned names within the existing system have also be renamed, for example:The DPB1*0102 becomes DPB1*100:01DPB1*0203 becomes DPB1*101:01DPB1*0302 becomes DPB1*102:01DPB1*0403 becomes DPB1*103:01DPB1*0502 becomes DPB1*104:01 etcHLA-C allele names, but will be retained in the HLA-C antigen names, to avoid confusion with the factors of the complement system and epitopes on the HLA-C molecule often termed C1 and C2 that act as ligands for the Killer-cell Immunoglobulin-like Receptors.The \u2018w\u2019 will be removed from the Cw*0103 becomes C*01:03Cw*020201 becomes C*02:02:01Cw*07020101 becomes C*07:02:01:01 etcwww.ebi.ac.uk/imgt/hla) , 28 and The level of resolution achieved by many of the HLA typing technologies employed today does not always allow for a single HLA allele to be unambiguously assigned. Often it is only possible to resolve the presence of a number of closely related alleles. This is referred to as an ambiguous \u2018string\u2019 of alleles. In addition, typing strategies are frequently aimed at resolving alleles that encode differences within the peptide binding domains, but fail to exclude those that differ elsewhere. For some purposes it is helpful to provide codes that aid the reporting of certain ambiguous alleles \u2018strings\u2019. The decision was taken to introduce codes to allow for the easy reporting of:a. HLA alleles that encode for identical peptide binding domainsHLA alleles having nucleotide sequences that encode the same protein sequence for the peptide binding domains will be designated by an upper case \u2018P\u2019 which follows the allele designation of the lowest numbered allele in the group.For example the string of allele names below share the same \u03b11 and \u03b12 domain protein sequence encoded by exons 2 and 3.A*02:01:01:01/A*02:01:01:02L/A*02:01:01:03/A*02:01:02/A*02:01:03/A*02:01:04/A*02:01:05/A*02:01:06/A*02:01:07/A*02:01:08/A*02:01:09/A*02:01:10/A*02:01:11/ A*02:01:12/A*02:01:13/A*02:01:14/A*02:01:15/A*02:01:17/A*02:01:18/A*02:01:19/A*02:01:21/A*02:01:22/A*02:01:23/A*02:01:24/A*02:01:25/A*02:01:26/A*02:01:27/ A*02:01:28/A*02:01:29/A*02:01:30/A*02:01:31/A*02:01:32/A*02:01:33/A*02:01:34/A*02:01:35/A*02:01:36/A*02:01:37/A*02:01:38/A*02:01:39/A*02:01:40/A*02:01:41/ A*02:01:42/A*02:09/A*02:66/A*02:75/A*02:89/A*02:97:01/ A*02:97:02/A*02:132/A*02:134/A*02:140A*02:01PThis string can be reduced to b. HLA alleles that share identical nucleotide sequences for the exons encoding the peptide binding domainsHLA alleles that have identical nucleotide sequences for the exons encoding the peptide binding domains will be designated by an upper case \u2018G\u2019 which follows the allele designation of the lowest numbered allele in the group.For example the string shown below consists of alleles that have identical nucleotide sequences in exons 2 and 3.A*02:01:01:01/A*02:01:01:02L/A*02:01:01:03/A*02:01:08/A*02:01:11/A*02:01:14/A*02:01:15/A*02:01:21/A*02:09/A*02:43N/A*02:66/A*02:75/A*02:83N/A*02:89/A*02:97:01/A*02:97:02/A*02:132/A*02:134/A*02:140A*02:01:01GThis string can be reduced to www.ebi.ac.uk/imgt/hla) (These reporting codes will be implemented in April 2010 and will be made available through the IMGT/HLA Database (mgt/hla) , 28 and HLA-A gene, for example A*03:01 and the expressed protein product of the same gene A*03:01.Discussions took place on the use of nomenclature for defining HLA allele sequences at the gene and protein level. The committee recommended the use of standard genetic nomenclature where gene symbols are in uppercase and italicised and protein symbols are the same as the gene symbols but are not italicised. Using this approach it is possible to discriminate between an allele of the Additionally it was recommended that when reporting an ambiguous string of HLA alleles, a forward slash (/) should be used as the separator to indicate \u2018or\u2019. When reporting genotypes it was recommended to use a comma to indicate \u2018and\u2019. Hence an HLA type may be reported as:A*02:01/02:09, 03:01; B*07:02, 15:02/15:73; C*03:03, 07:02www.ebi.ac.uk/imgt/hla.The IMGT/HLA Sequence Database continues to act as the official repository for HLA sequences named by the WHO Nomenclature Committee for Factors of the HLA System , 28. TheThe IMGT/HLA Database is currently supported by the following organisations: Histogenetics, Abbott, Biotest, Invitrogen, One Lambda, Olerup SSP, Gen-Probe, The Anthony Nolan Trust (ANT), The American Society for Histocompatibility and Immunogenetics (ASHI), The European Federation for Immunogenetics (EFI), Innogenetics, BAG Healthcare, Be the Match Foundation and the National Marrow Donor Program."} +{"text": "The first author's name appears incorrectly. It should read: Boris V. Schmid. The correct citation should read: Schmid BV, Ke\u015fmir C, de Boer RJ (2008) The Specificity and Polymorphism of the MHC Class I Prevents the Global Adaptation of HIV-1 to the Monomorphic Proteasome and TAP. PLoS ONE 3(10): e3525. doi:10.1371/journal.pone.0003525"} +{"text": "British Journal of Cancer (2002) 87, 689\u2013689. doi:10.1038/sj.bjc.6600504www.bjcancer.comCancer Research UK\u00a9 2002 Correction to:British Journal of Cancer (2002) 86, 1270. doi:10.1038/sj/bjc/6600232 The authors would like to thank InSight Ltd., Rehovot, Israel for providing them with the anti-heparanase antibody and heparanase cDNA used in the study.The mentioned reagents are proprietary of InSight."} +{"text": "There was an error in the title of the article. The correct title should read: Functional and Molecular Effects of Arginine Butyrate and Prednisone on Muscle and Heart in the Dystrophin Deficient mdx mice. The correct citation is: Guerron AD, Rawat R, Sali A, Spurney CF, Pistilli E, et al. (2010) Functional and Molecular Effects of Arginine Butyrate and Prednisone on Muscle and Heart in the Dystrophin Deficient mdx mice. PLoS ONE 5(6): e11220. doi:10.1371/journal.pone.0011220"} +{"text": "Ma'i Suka: Individual, Familial, Cultural, and Environmental Stress Among Patients With Type 2 Diabetes Mellitus and Their Caregivers in American Samoa,\" which appeared in the July 2008 issue, was amended to include a footnote that was missing in the original publication. The footnote indicates that the column headed \"Total Participants\" includes 3 caregivers with diabetes. The changes were made June 25, 2008, and appear online at www.cdc.gov/pcd/issues/2008/jul/07_0101.htm.Table 2 in the article \"Living With"} +{"text": "Correction to:British Journal of Cancer (2004) 91, 1000. doi:10.1038/sj.bjc.6602070Due to an error, the ISBN number of the book reviewed above was given incorrectly. The correct number is shown below:ISBN \u2013 1588292282."} +{"text": "Correction to: British Journal of Cancer (2010) 103, 209-216; doi:10.1038/sj.bjc.6605747Owing to an error during final correction of this paper, Figure 3 was incorrectly reproduced. The correct"} +{"text": "Correction to:British Journal of Cancer (2003) 88, 502\u2013509. doi:10.1038/sj.bjc.6600797Unfortunately because of a typesetting error, Tables 1The publisher would like to apologise for any inconvenience this may have caused."} +{"text": "Correction to:British Journal of Cancer (2007) 96, 1293\u20131301. doi:10.1038/6603696In the abstract of the above paper, a peptide with correct sequence (TLMKKDKYTL) is mentioned. This sequence should also appear in The corrected"} +{"text": "Correction to: British Journal of Cancer (2008) 98, 1586\u20131592. doi: 10.1038/sj.bjc.6604303During the correction process for this article, incorrect versions of the graphs contained in The corrected"} +{"text": "Correction to:British Journal of Cancer (2009) 101, 441\u2013451; doi:10.1038/sj.bjc.6605186Owing to an error during the final correction of this paper, panels E and F in The correct panels 4E and 4F are reproduced below:"} +{"text": "Acta Cryst. (2009), E65, o2008.Corrigendum to Acta Cryst. (2009), E65, o2008] is corrected and the acknowledgements are updated.The list of authors in the paper by Zhi, Long, Chen & Ren ["} +{"text": "Correction to: British Journal of Cancer (2006) 95, 363\u2013365. doi:10.1038/sj.bjc.6603250Owing to an author error, there was a mistake in the presentation of results in"} +{"text": "Correction to:British Journal of Cancer (2003) 88, 613\u2013623; doi:10.1038/sj.bjc.66000681 The enzyme was prepared by the overexpression of biosynthetic arginine decarboxylase , who kindly provided the enzyme for CDN Wheatley"} +{"text": "Correction to:British Journal of Cancer (2010) 102, 232\u2013233. doi: 10.1038/sj.bjc.6605446Upon publication of this Letter to the Editor, it was noted that the affiliation for Dr Mark Nuijten had been presented incorrectly. The correct affiliation for Dr Nuijten is \u2018Ars Accessus Medica in Amsterdam, Dorpsstraat 75 1546 LG, The Netherlands\u2019."} +{"text": "El Mouzan et al. Prevalence of malnutrition in Saudi children: a community-based study. Ann Saudi Med 2010;30(5):381-385. PMID: 20697172. Some data in some of the tables (and the corresponding data in the text) are corrected as indicated. Changes are highlighted."} +{"text": "Correction to: British Journal of Cancer (2008) 99,, 1185\u20131190, doi: 10.1038/sj.bjc.6604657The surname of Driss Ait Ouakrim was published incorrectly when this paper appeared in volume 99, issue 7. The author's name is given correctly, above."} +{"text": "Correction to:British Journal of Cancer 2003; 89 (S1), S9\u2013S11 doi:10.1038/sj.bjc.6601078 Unfortunately, due to an error, the tables were omitted from the above article.All the three tables (The publisher would like to apologise for any inconvenience this error may have caused."} +{"text": "Correction for:10.1371/journal.pbio.0060265Welch DW, Rechisky EL, Melnychuk MC, Porter AD, Walters CJ, et al. (2008) Survival of migrating salmon smolts in large rivers with and without dams. PLoS Biol 6(10): e265 doi:In the legend below Table 1, the reference given at the end of the second sentence is incorrect. The sentence should read:\u201cAnnual survival (S) to the lowest listening line in the Fraser River, whole-river survival in the Columbia River (2006), and associated detection efficiencies (p) were calculated using the CJS model and program MARK [28]\u201d"} +{"text": "PLoS Pathog 3(4): e43. doi: PLoS Pathogens, volume 3, issue 4:In The funding statement for the above paper was incomplete. The full funding statement follows.Funding. This work was supported by grants from the National Institutes of Health . JDB is supported by K01 AI 066917 ."} +{"text": "Correction to: British Journal of Cancer (2006) 95, 87\u201390. doi:10.1038/sj.bjc.6603175P-values. The final sentence of the Results section should read:Owing to an author error, the final paragraph within the results section of this paper quoted erroneous P-values for trend: 0.199 and 0.043, for males and females, respectively).\u2019\u2018Rates were somewhat higher in deprived areas, but this trend is only significant for females ("} +{"text": "Correction to: British Journal of Cancer (2006) 96, 336\u2013340. doi:10.1038/6603492British Journal of Cancer website (http://www.nature.com/bjc).Owing to a publishing error, part of the intended"} +{"text": "Correction to: British Journal of Cancer (2009) 101, 1909\u20131918; doi:10.1038/sj.bjc.6605405Upon publication of this paper in the last issue, an error was spotted in the clinical data in"} +{"text": "Correction to Lindsay H, Yap VB, Ying H, Huttley GA: Pitfalls of the most commonly used models of context dependent substitution. Biology Direct 2008, 3:52 The published version of this article includesScripts used in the study. Archive of stand-alone web site presenting the central scripts used in this study.Click here for file"} +{"text": "Correction to:British Journal of Cancer (2003) 89, 1285\u20131289. doi:10.1038/sj.bjc.6601208A couple of errors have been noted in Table 2The Publisher would like to apologise for any inconvenience this may have caused."} +{"text": "Environ Health Perspect 118:20\u201332 (2010)], Orton et al. (2006) was cited on page 26 but was not included in the reference list. The reference is as follows:In the review by Rohr and McCoy [Rana pipiens. Environ Toxicol Chem 25:65\u201371.Orton F, Carr JA, Handy RD. 2006. Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog"} +{"text": "Correction to: British Journal of Cancer (2008) 97, 857\u2013861, doi:10.1038/sj.bjc.6603942The authors of the above paper, first published in October 2007, would like to add the following acknowledgement to their paper:We thank Programme Hospitalier de Recherche Clinique (PHRC)."} +{"text": "Correction to:British Journal of Cancer (2006) 94, 1853\u20131863. doi:10.1038/6603190Owing to a publishing error,"} +{"text": "Correction to: British Journal of Cancer (2010) 103: 668\u2013675; doi:10.1038/sj.bjc.6605736Upon publication of the above paper in Volume 103, Issue 5, the authors noticed an error in The correct"} +{"text": "Correction to:British Journal of Cancer (2004) 90, 1756\u20131759. doi:10.1038/sj.bjc.6601763Due to an error, On page 1756 of this article, the second sentence in the Results section should read as follows:The incidence of hysterectomies with cervix removed increased from 2500 in 1991 to 2017 per million women in 1999."} +{"text": "Correction to: British Journal of Cancer (2007) 97, 73\u201384. doi: 10.1038/sj.bjc.6603835The authors of the above paper would like to add two author names to the list originally published in Volume 97, Number 1; the full author list is given above, including E Taoufik and E Probert."} +{"text": "Correction to: British Journal of Cancer (2006) 95, 1314\u20131320. doi: 10.1038/6603457Owing to an error on the author's part, the last named author (JY Shin) was omitted from the author listing when the paper was originally published. The full, correct author listing is now shown above."} +{"text": "Environ Health Perspect 118:A422\u2013A423 (2010)], one reference cited in the text was inadvertently omitted from the reference list. The reference for Grulich et al. (2007) is as follows:In the editorial by Fontham and Trapido [Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. 2007. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 370(9581):59\u201367.EHP apologizes for the error."} +{"text": "Acta Cryst. (2010), E66, o217.Corrigendum to Acta Cryst. (2010), E66, o217] is corrected.The absolute configuration in the title of the paper by Wang, Zhang, Xu & Zhang [ The absolute configuration was established by anomalous-dispersion effects in diffraction measurements on the crystal. The revised scheme is shown below. In the paper by Wang"} +{"text": "Correction to: British Journal of Cancer (2006) 94, 1326\u20131332. doi:10.1038/6603101Owing to an author error, the incorrect"} +{"text": "Correction to: British Journal of Cancer (2009) 101, 395\u2013402; doi:10.1038/sj.bjc.6605155Upon publication of this paper in Volume 101, the authors noticed an error in the legend of"} +{"text": "There are errors in the Funding section. The correct funding information is as follows: This research was supported by the World Health Organization through a grant received from the Japan International Cooperation Agency (JICA). The World Health Organization was actively involved in study design, data collection and analysis, decision to publish, and preparation of the manuscript. JICA had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.http://www.who.int/gho/en/.]There is an error in reference 1. The correct reference is: World Health Organization. Global health observatory data repository 2015: WHO; 2015 There is an error in reference 7. The correct reference is: World Health Organization. Maternal mortality 2014; Fact sheet No. 348: WHO; 2014 There is an error in reference 12. The correct reference is: World Health Organization. Practical guide for the design, use and promotion of home-based records in immunization programmes: WHO; 2015 There is an error in reference 17. The correct reference is: Magwood O, Kpade V, Thavorn K, Oliver S, Mayhew AD, Pottie K. Effectiveness and cost-effectiveness of home-based records on maternal, newborn and child health outcomes: a protocol for a WHO systematic review and meta-analysis. Ottawa: Cochrane Equity Methods; 2017 [Available from: http://www.who.int/reproductivehealth/publications/maternal_perinatal_health/anc-positive-pregnancy-experience/en/.]There is an error in reference 18. The correct reference is: World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience: WHO; 2016 [Available from: http://www.who.int/topics/infant_newborn/en/.]There is an error in reference 19. The correct reference is: World Health Organization. Infant, Newborn: WHO; 2017 [Available from: There is an error in reference 21. The correct reference is: Cochrane Effective Practice and Organisation of Care (EPOC). What study designs should be included in an EPOC review? EPOC resources for review authors 2017 [Available from: epoc.cochrane.org/epoc-resources-review-authors.]There is an error in reference 24. The correct reference is: The Cochrane Collaboration. Review Manager (RevMan) version 5.3. 5.3 ed: The Cochrane Collaboration; 2014.There is an error in reference 35. The correct reference is: John Snow Inc. (JSI). Home-Based Record Redesigns That Worked: Lessons from Madagascar & Ethiopia. USA: JSI; 2016.There is an error in reference 36. The correct reference is: Japan International Cooperation Agency (JICA). Study on the use of the Maternal and Child Health Handbook in the Maternal and Child Health Project\u2013Knowledge, Lessons and Challenges. Japan: JICA; 2012."} +{"text": "Randomised controlled pilot feasibility trial of an early intervention programme for young infants with neurodevelopmental impairment in Uganda: a study protocol. BMJ Open 2019;9:e032705. doi: 10.1136/bmjopen-2019-032705.Nampijja M, Webb E, Nanyunja C, This article was previously published with an error.The first author of reference 2 was omitted. The correct reference is:et al. Global Research on Developmental Disabilities Collaborators. Developmental disabilities among children younger than 5 years in 195 countries and territories, 1990\u20132016: a systematic analysis for the global burden of disease study 2016. Lancet Glob Health 2018;6:e1100\u201321.Olusanya BO, Davis AC, Wertlieb D,"} +{"text": "International Journal of Oral Science (2015) 7, 205\u2013212; 10.1038/ijos.2015.29; published 18 September 2015Correction to: In the original version of this Article, Fig."} +{"text": "Correction to: British Journal of Cancer (2016) 94, 1765-1769; 10.1038/sj.bjc.6603170; published online 23 May 2006.Since the publication of this paper, the authors have reported that there is an error in the chemical structure for imatinib presented in Fig."} +{"text": "Correction to: BMC Systems Biology 2018, 12(Suppl 8):128https://10.1186/s12918-018-0651-1It was highlighted that the original article containeFig. 6 legendP-value <\u20090.05 and supporting reads number\u2009>\u2009=2) contains two domains: Biological Process and Cellular Component.GO enrichment analysis of the mRNA in the co-expression network. The GO analysis . Z.Z was partially supported by National Institutes of Health grants (R21CA196508 and R01LM012806). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.Fig. 6 legendcircRNA-mRNA co-expression network. Red box represents mRNA; blue triangle represents miRNA, and green circle represents circRNA.FundingPublication of this article was funded by the National Natural Science Foundation of China (No.81270700 and No. 61571223). Z.Z was partially supported by National Institutes of Health grants (R21CA196508 and R01LM012806). The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."} +{"text": "Wind coming from the West, compared to wind coming from other directions, was the most favourable for performance of all groups of finishers. Increasing precipitations worsened performances of top 100 and top 10 finishers . Wind speed, when increasing by 1 km/h, was related to worsened performance for all finishers , but not for top 100 group, where performances were 00:00:09 h:min:sec faster, p < 0.001. Pressure and WBGT were examined in uni-variable models: overall, performances worsened as pressure and WBGT increased. Our findings contributed to the knowledge about the effect of weather conditions on performance level in male marathon runners.This study investigated the effects of weather conditions on male performance during the Boston Marathon from 1897 to 2018. A total of 383,982 observations from 244,642 different finishers were analysed using Generalized Additive Mixed Models. All runners, annual top 100 finishers and annual top ten finishers were considered. Weather conditions, on race day, were: average air temperature (\u00b0C), precipitations (mm), wet-bulb globe temperature (WBGT) (\u00b0C), wind speed (km/h), wind direction and pressure (hPa). These effects were examined in multi-variable models with spline smooth terms in function of calendar year. Temperature, when increasing by 1 \u00b0C, was related to worsened performance for all groups (i.e., by 00:01:53 h:min:sec for all finishers, Environmental conditions seem to have an important effect on marathon running performance. Temperature, humidity and wind could influence the thermoregulatory anticipation to the increased heat gained during a marathon race . An ambiThe Boston Marathon has the longest tradition in marathon running since its start in 1897 and several studies have investigated the influence of environmental conditions on race performance ,13,14,15Therefore, the aim of the present study was to examine the effect of weather conditions on race time of male runners in the Boston Marathon from 1897 to 2018. This marathon race provided a unique model to conduct research on the effect of weather conditions considering their variability among calendar years. We hypothesized to find difference regarding existing literature when investigating the whole period of time and including all male annual finishers as well as the annual top 10 and the annual top 100 male finishers.All procedures used in the study were approved by the Institutional Review Board of Kanton St. Gallen, Switzerland, with a waiver of the requirement for informed consent of the participants given the fact that the study involved the analysis of publicly available data (01/06/2010).www.baa.org/races/boston-marathon/boston-marathon-history.aspx). To compete in this race, athletes must meet time standards which correspond to age and sex . Data, collected annually from 1897 to 2018 for men were obtained from the official race website (www.baa.org/races/boston-marathon.aspx). Available information from the race records were name and surname of the runners, sex and runners\u2019 nationality, year of competition, and race times.The Boston Marathon is the world\u2019s oldest annual marathon, where the course is a point-to-point race with its start in Hopkinton and finishing on Boylston Street in Boston, MA. (We cleaned the dataset removing runners with missing or questionable (unreliable) information on race time. Unfortunately, we did not have the complete list of all runners belonging to push rim wheelchair division, started on 1975 for men. We excluded this category eliminating runners with race time shorter than the annual top record. To identify observations from a single runner, we defined an id variable with name, surname, nationality and period of competition, supposing that a single runner could participate at most for 25 years.Temperature, and speed and direction of wind, seemed to have an influence on race time in the Boston Marathon ,13,14,22www.wunderground.com/history/airport/KBOS/2013/1/15/MonthlyHistory.html for 1930 to 2018 and from https://w2.weather.gov/climate/local_data.php?wfo=box for 1897 to 1929. WBGT was calculated with https://www.kwangu.com/work/psychrometric.htm using the dry bulb temperature and relative humidity obtained from www.wunderground.com and an altitude of 43 m above sea level.Weather data were obtained from two different websites for this period from 1897 to 2018 from Descriptive statistics were presented as means \u00b1 standard deviations for continuous variables and as number N (%) for categorical variables. Performance, or race time, was recorded in the format \u201chours:minutes:seconds\u201d. Different analyses were performed for the following groups of finishers: all runners, annual top 100 and annual ten finishers. Average performances, by sex and weather conditions, were reported for the following groups: temperature of 0\u20137, 8\u201315, 16\u201323, 24\u201330 \u00b0C, precipitations equal 0 or >0 mm, WBGT of 0\u20136, 7\u201310, 11\u201315, 16\u201320 \u00b0C, wind speed of 0\u201315, 16\u201317, 18\u201338 km/h, and pressure < 1015 or \u22651015 hPa. Wind direction was defined as: East , West , North , South . T-tests or ANOVA tests, with post-hoc Dunn\u2019s test for pairwise multi-comparison of means, where appropriate, were performed, but p-values were not shown in tables.p < 0.05.Data visualization was used to identify the uni-variable relationship between performance and each weather variable. Moreover, association between weather conditions was preliminary investigated through the correlation matrix, which showed the pairwise correlation among all the variables. As a result, the effects of calendar year on race time, together with the effects of weather conditions, were examined through multi-variable statistical models. Results were presented as estimates (standard errors). The acceptable type I error was set at Race Time (Y) ~ [Fixed effects (X) = Weather Conditions + S+ [Random effects of intercept = Runners]where S denoted a spline, changing with calendar year and with k basis dimension. K was set equal to nine. Observations before 1944 were discarded because of incomplete information about weather conditions. As a first analysis, all weather variables: temperature, WBGT, precipitations, wind direction, wind speed, and pressure were included into the multi-variable model. Subsequently, WBGT and pressure were discarded, in all groups of finishers, due to multi-collinearity, assessed by computing the variance inflation factor (or VIF) score. All predictors with VIF not greater than 10 were retained in the model. According to this criterion, in all finishers group, precipitations variable was also dropped. Instead, in top ten finishers the wind speed variable was discarded. Partial effects, which are the isolated effects of one particular predictor or interaction, were shown graphically. Moreover, the effects of pressure and WBGT on performance, discarded in the multi-variable model, where also assessed, more rigorously, through uni-variable linear mixed models, which corrected for repeated measurements.Different models were performed, one for each group of finishers. Calendar year was considered as a discrete value of a continuous variable. Temperature, precipitation, WBGT, wind speed and pressure were considered as continuous variables. Spline regression models were used, with a spline smooth term in function of calendar year and a linear term in function of the other effects. Preliminary data visualization and previous research ,23 justihttps://www.R-project.org/). In particular, we used the following R packages: PMCMR for Pairwise post-hoc Test for Multiple Comparisons of Means; ggplot2 for preliminary data visualization; GGally for plotting the correlation matrix and the association between explanatory variables; gamm4 for multi-variable mixed models with random effects on intercept; mgcv for statistical models visualization; lmer for linear mixed models.All statistical analyses were carried out using statistical package R, R Core Team (2016). R: A language and environment for statistical computing. . In Between 1897 and 2018, a total of 383,982 observations from 244,642 different finishers were recorded in the race results. In Before carrying out multi-variable analysis, association between weather variables was examined and reported in After that, the effects of each weather variable, on performance of all groups of finishers, were shown in p < 0.001 in all finishers; 00:00:37 (00:00:02) h:min:sec, p < 0.001 in top 100 finishers and 00:00:38 (00:00:03) h:min:sec, p < 0.001 in top 10 finishers. When wind speed increased by 1 km/h, performances of all finishers worsened but performances of top 100 group improved. In fact, the wind speed estimates was positive in all finishers: 00:00:19 (00:00:01) h:min:sec, p < 0.001 and negative in top 100 group: \u221200:00:09 (00:00:01) h:min:sec, p < 0.001. When precipitations increased by 1 mm, performances significantly worsened: by 00:00:04 (00:00:01) h:min:sec, p < 0.001 in top 100 group and by 00:00:05 (00:00:01) h:min:sec, p < 0.001 in top 10 group. Performances with wind coming from the West, were significantly better compared to the other wind directions (p < 0.001). In fact, estimates were positive, which meant worse performance compared to the West, the reference wind direction category. The wind direction had the greatest effects, in terms of estimates, in all finishers, compared to the other groups of finishers, when the wind came from the East and from the South. In fact, when the wind direction was the East, performances, compared to performances when wind direction was the West, were slower by: 00:11:18 (00:00:11) h:min:sec, p < 0.001, in all finishers, against 00:03:09 (00:00:27) h:min:sec, p < 0.001, in top 100 group and 00:03:54 (00:00:38) h:min:sec, p < 0.001 in top 10 group. Analogously, when the wind direction was the South, performances, compared to performances when wind direction was the West, were slower by 00:09:41 (00:00:10) h:min:sec, p < 0.001 in all finishers, against 00:01:13 (00:00:33) h:min:sec, p < 0.05 in top 10 group. In top 100 group, the difference between performances, when wind direction was the South and performances when wind direction was the West, was not significant. When the wind direction was the North compared to the West, the greatest difference was observed in all finishers: 00:05:30 (00:00:11) h:min:sec, p < 0.001 against 00:01:51 (00:00:38) h:min:sec, p < 0.001 in top 10 group and 00:01:30 (00:00:25) h:min:sec, p < 0.001 in top 100 group.In p < 0.001 in all finishers, 00:00:09 (00:00:01) h:min:sec, p < 0.001 in top 100 groups and 00:00:04 (00:00:02) h:min:sec, p < 0.05 in top ten group. Instead, when WBGT increased by 1 \u00b0C, performances of all groups of finishers were significantly slower: by 00:01:55 (00:00:01), p < 0.001 in all finishers, by 00:00:22 (00:00:03) h:min:sec, p < 0.001 in top 100 group and by 00:00:26 (00:00:06) h:min:sec, p < 0.001 in top 10 group.Since the uni-variable relationships, plotted in p < 0.001 in all groups. The greatest smoothing terms, in absolute value, were observed in all finishers where the trend was overall increasing, even if in some years was decreasing. This meant that performances had overall worsened over time. In top 100 and top 10 groups, instead, the temporal trend of performance was overall decreasing, even if not monotonically, meaning that performance had overall improved over time.Performances changed significantly over calendar year. In fact, in To visualize the most important results of p < 0.001) worsened performance by 00:01:53 h:min:sec for all finishers, 00:00:37 h:min:sec for annual top 100 finishers and 00:00:38 h:min:sec for annual top 10 finishers; (ii) wind coming from the West, compared to wind from other directions, was the most favourable for performance of all groups of finishers. In particular, for all finishers, performances when wind came from the West were: 00:09:41 h:min:sec faster (p < 0.001), compared to performances when wind came from the South, 00:11:18 h:min:sec faster (p < 0.001), compared to performances when wind came from the East and 00:05:30 h:min:sec faster (p < 0.001), compared to performances when wind came from the North; (iii) precipitations, when increasing by 1 mm, worsened performances of top 100 and of top 10 groups by 00:00:04 h:min:sec and 00:00:05 h:min:sec (p < 0.001), respectively; (iv) wind speed, when increasing, also worsened performances for all finishers , but not for top 100 group, where performances were 00:00:09 h:min:sec faster, p < 0.001; (v) pressure, when increasing, had a negative effect on performance in all group of finishers; (vi) WBGT when increasing, had a negative effect on performance of all groups of finishers.The main findings of the present study were that: (i) average temperature, when increasing by 1 \u00b0C, significantly (The direct relationship of race times with temperature, i.e., the hotter the temperature, the slower the race time, was in agreement with previous observations in marathon races ,12. For The findings of the present study were limited by the specific characteristics of the race in terms of participation and weatIn summary, race times in the Boston Marathon are influenced by temperature, pressure, precipitations, WBGT, wind coming from the West and wind speed. The magnitude and the direction of the influence of the abovementioned weather conditions on race time varied by performance level. Our findings improved the knowledge about the association between weather conditions and their relationship with performance level in male marathon runners. Considering the popularity of the particular marathon and of marathon races in general , the res"} +{"text": "Elizabethkingia Acquisition and Clinical Characteristics of Patients, South Korea . The corrected figure is shown, and the article has been corrected online (https://wwwnc.cdc.gov/eid/article/25/1/17-1985_article).Two locations in Figure 1 were shown incorrectly in Risk Factors for"} +{"text": "Bioinformatics (2019) doi: 10.1093/bioinformatics/bty873, 35, 1783\u20131785.In the original article, there was an error in the formatting of Table 1.This has been corrected and the corrected table appears below."} +{"text": "Correction to:Cell Death and Disease (2016) 7, e2419; 10.1038/cddis.2016.268, Published online 13 October 2016.Since the publication of the article, the authors became aware that Fig.\u00a0The authors apologise for any inconvenience caused."} +{"text": "There is an error in the reference for the source of the mathematical model used in this manuscript. The authors cited Chow&Hall 2008 instead of Hall et al. 2011. Both articles have Hall in their authorship. While Chow&Hall (2008) explains the model conceptualization and the model behavior with non-real simulations, Hall et al. (2011) explains the model implementation to the adult population with real data. The correct citation for reference #27 should read:27. Hall KD, Sacks G, Chandramohan D, Chow CC, Wang YC, Gortmaker SL, et al. Quantification of the effect of energy imbalance on bodyweight. Lancet. 2011;378: 826\u2013837. doi:10.1016/S0140-6736(11)60812-XThe reference is made several times throughout the paper, and therefore the following should be corrected:http://ensanut.insp.mx/). The final dataset after running the Hall and colleagues\u2019 model is available at the open science framework, available at https://osf.io/vfcm8/ (DOI: 10.17605/OSF.IO/VFCM8). The mathematical model used to estimate the impact on body weight is freely available within an R package version 1.0.0 named \u2018bw\u2019 in https://cran.r-project.org/web/packages/bw/index.html.The Data Availability Statement should read: Baseline added sugar consumption from SSBs and weight were obtained from the 2012 Mexico National Health and Nutrition Survey .\u201dThe first three sentences of the third paragraph in the Discussion section should read: Body weight modeling is a complex task, as many components and interrelationships need to be considered. In this paper, we used the model proposed by Hall and colleagues, which has been widely used to estimate the impact of nutritional policies, including the potential impact of sugar reformulation in SSBs [41]. Hall and colleagues\u2019 model is a physiological model that has been validated against experimental data and can be implemented using individual-level or aggregated data; however, other models to estimate weight change are available.\u201d"} +{"text": "This article has been corrected: The authors requested to replace Figure 3 and Figure 6. The mistakes of these figures are described below:Figure 3: the Westernblot of SDHB in Figure3B of MCF-7 flipped horizontally.Figure 6: the Westernblot of Cytc in Figure6B of MDA-231 was identical to Uqcrfs1 due to the layout mistakes.These corrections do not change any of the conclusions of the publication. The corrected Figure 3 and Figure 6 are provided below.https://doi.org/10.18632/aging.102442.Original article: Aging. 2019; 11:10203\u201310219."} +{"text": "Increasing wind speed was also related to worsened performances in all finishers and near elite groups. Kenyans and Ethiopians were the fastest nationalities. The sex differences were the largest in near elite groups. Our findings contributed to the knowledge of the performance in Boston Marathon across calendar years, considering as main effects weather conditions, country of origin and sex.This study examined the relationship of weather conditions, together with sex and country of origin, with running performance in the Boston Marathon from 1972 to 2018. A total of 580,990 observations from 382,209 different finishers were analyzed using Generalized Additive Mixed Models. Different groups and subgroups were considered such as all runners, near elite 101:200 finishers, near elite 21:100, annual top ten finishers and annual winners. Weather conditions, over the hours of the event, were average air temperature (\u00b0C), total precipitations (mm), wet-bulb globe temperature (WBGT) (\u00b0C), wind speed (km/h), wind direction and barometric pressure (hPa). These effects were examined in a multi-variable model, together with: sex, country of origin, calendar year, an interaction term country:sex and a spline smooth term in function of calendar year and sex. The average temperature, when increasing by 1\u00b0C, was related to worsened performance . Also, the pressure and wet-bulb globe temperature, when increasing, were related to worsened performances. Tail wind improved performances of all groups. Increasing precipitation was significantly ( To date, the influence of different environmental conditions such as ambient air temperature wind, precipitations, barometric pressure, humidity, dew point, cloud cover, solar irradiation and atmospheric pollutants have been investigated in marathon running performance \u20137. It isThe Boston Marathon has the longest tradition in marathon running (it started in 1897 and the first woman participated in 1972) and several studies investigated the influence of environmental conditions on race performance ,11. Howei.e. head wind, side wind, tail wind) and barometric pressure (hPa). These effects were analyzed together with sex, country of origin and calendar year. Based upon previous research, we hypothesized that increasing air temperature impaired running performance in both elite and sub-elite runners.The aim of the present study was to investigate the role of weather conditions, together with sex and country, on female and male performance in the Boston Marathon from 1972 to 2018 since in 1972 the first women officially participated in a marathon. We considered the effects, over the hours of the event, of average air temperature (\u00b0C), total precipitations (mm), wet-bulb globe temperature (WBGT) (\u00b0C), wind speed (km/h), wind direction . To compete in this race, athletes must meet time standards which correspond to age and sex . Data are freely available from the Boston Athletic Association website (www.baa.org) and Marathon Guide website (www.marathonguide.com). Data involved in this study are race results from 1972 to 2018 for women and men. Available information from the race records were name and surname of the runners, sex and runners\u2019 nationality, year of competition, and race times. We cleaned the dataset correcting for double coding of the same level of categories as reported earlier [www.wunderground.com/history/daily/us/ma/boston/KBOS and all units were converted to the metric system. All weather data was stored in www.kwangu.com/work/psychrometric.htm using the dry bulb temperature and relative humidity obtained from www.wunderground.com/ and an altitude of 43 m above sea level. The total precipitation (mm) was the sum over the duration of the race of the hourly amount of precipitations. The wind direction was the most frequent determination over the hourly observations which were classified as: head wind , side wind and tail wind [www.baa.org/races/boston-marathon/course-map).The Boston Marathon is the world\u2019s oldest annual marathon due to ti.e. or race time) was recorded in the format \u201chours:minutes:seconds\u201d. Average performances, by sex and weather conditions, were reported for the following groups: temperature of 0\u20137 \u00b0C, 8\u201315 \u00b0C and 16\u201324 \u00b0C; wind direction head, side or tail; total precipitations equal 0 and >0 mm; WBGT of 0\u20136 \u00b0C, 7\u201310 \u00b0C, 11\u201315 \u00b0C and 16\u201320 \u00b0C; wind speed of 9\u201317 km/h, 18\u201324 km/h and 25\u201339 km/h; pressure <1015 hPa and \u22651015 hPa. The effects of calendar year on race time, together with the effects of sex, country of origin and weather conditions, were examined through multi-variable statistical models. Results were presented as estimates (standard errors). Different analyses and regression models were performed for the following subgroups: all runners, annual top 101:200, annual top 21:100, annual top ten finishers and annual winners. The calendar year of the race was considered as a discrete value of a continuous variable. The country groups included the 8 most prevalent geographical areas in terms of participation . For annual top finishers (winners) country groups were only 4: Kenya-Ethiopia, Europe, USA and other countries. Weather characteristics such as: temperature, precipitations, WBGT, wind speed and pressure were considered as continuous variables. Wind direction as a categorical variable. The acceptable type I error was set at p<0.05. Preliminary data visualization and previous research [https://www.R-project.org/. In particular, we used the following R packages: ggplot2 for preliminary data visualization; gamm4 for multivariable mixed models with random effects on intercept; mgcv for statistical models visualization. The R script, used to manage data and to run the analyses, was provided in Descriptive statistics were presented as means \u00b1 standard deviations for continuous variables and as number N (%) for categorical variables. Performance . Instead, women performed better when there was head wind in most cases. Performances were also better, most frequently, with absence of precipitations for women and for men, on the contrary, with presence of precipitations. When considering wet-bulb globe temperature, when the level was 0\u20136 \u00b0C, both men and women performed better in all cases except all male finishers. In most cases, when wind speed was 18\u201324 km/h, men and women performed better. Both sexes performed better, in most cases for women and in all cases for men, when pressure <1015 hPa. In In In p<0.001 and a smaller effect for annual winners 00:00:20 (00:00:05) h:min:sec, p<0.001. For the annual top ten, a temperature variation effect on performance was not significant. As pressure increased by one hPa, performances significantly worsened with a greater effect for all finishers: 00:00:06 (00:00:00) h:min:sec, p<0.001 and a smaller effect for the annual top 101:200 finishers: 00:00:03 (00:00:00) h:min:sec, p<0.001. For the annual winners, an effect of pressure variation on performance was not significant. As wind speed increased by 1 km/h, performances significantly worsened with a greater effect for all finishers: 00:00:13 (00:00:00) h:min:sec, p<0.001 and a smaller effect for the annual top 21:100: 00:00:06 (00:00:01) h:min:sec, p<0.001. For the elite groups the effect of wind speed variation on performance was not significant. As precipitations increased by 1 mm, performances significantly worsened, with a greater effect for all finishers: 00:00:44 (00:00:01) h:min:sec, p<0.001 and equal effect for the other groups: estimate 00:00:10 h:min:sec. For the annual winners, a precipitations effect was not significant. A wet-bulb globe temperature effect was significant in all groups except winners. Analogously to the other weather effects, as wet-bulb globe temperature increased by 1 \u00b0C, performances worsened with a greater effect for near elite groups: 00:00:31 (00:00:03) h:min:sec, p<0.001 in top 21:100 group and a smaller effect for all finishers: 00:00:10 (00:00:02) h:min:sec, p<0.001. Performances of all groups were significantly slower with head and side wind compared to tail wind. The effects were greater for all finishers: compared to tail wind, head wind slowed down performance by 00:11:51 (00:00:10) h:min:sec, p<0.001 and side wind by 00:08:04 (00:00:09) h:min:sec, p<0.001. For the near elite finishers, in particular the top 101:200, the effects of wind direction were smaller: head wind slowed down performance by 00:03:06 (00:00:09) h:min:sec, p<0.001 and side wind by 00:01:37 (00:00:08) h:min:sec, p<0.001.As temperature, WBGT, pressure, precipitations or wind speed increased, performances significantly worsened in most cases. In fact, when average temperature increased by 1 \u00b0C, performances were slower with a greater effect for all finishers: 00:01:47 (00:00:01) h:min:sec, p<0.001, which was the comparison between Kenya\u2014Ethiopia and Central-South America, to a maximum of 01:45:14 (00:04:44) h:min:sec, p<0.001, which was the comparison between Kenya-Ethiopia and Asia. In the top ten group, the significant differences ranged from a minimum of 00:02:20 (00:01:04) h:min:sec, p<0.01, which was the comparison between Kenya\u2014Ethiopia and Asia, to a maximum of 00:03:00 (00:00:45) h:min:sec, p<0.001, which was the comparison between Kenya-Ethiopia and USA. The interaction terms country:sex represented the sex differences for each country group. For instance, the term Africa:M estimated how much greater the effect of being men on race time was for a runner from Africa, compared to a runner from Kenya-Ethiopia. From p<0.001. Men were significantly faster than women in all groups, with a greater effect in the near elite groups, in particular the top 101:200 finishers: 00:41:51 (00:00:11) h:min:sec, p<0.001 and a smaller effect in annual winners: 00:17:25 (00:01:24) h:min:sec, p<0.001. In all finishers group, being men was a significant factor when interacted with country. Moreover, performances changed significantly over calendar year for both sexes in all groups except men winners, where variations were small. The greater smoothing terms were observed in top 101:200 group. In all finishers the trend was overall increasing, after decreasing in the first ten years. In Athletes from Kenya and Ethiopia were significantly the fastest compared to every country group. The differences varied between sexes and between groups of finishers. The greater effects were observed for all finishers and the smaller effects for annual top 10 finishers. For women in all finishers group, the differences ranged from a minimum of 01:22:04 (00:04:45) h:min:sec, i) an increase of average temperature by 1 \u00b0C was related to worsened performance with greater effect for all finishers, (ii) increasing barometric pressure was related to worsened performances, (iii) wet-bulb globe temperature, analogously, when increasing was related to worsened performances, (iv) tail wind was related to improved performances of all groups, (v) precipitations, when increasing, were related to worsened performances, (vi) increasing wind speed was also related to worsened performances for all finishers and near elite groups.The aim of the present study was to investigate the role of weather conditions, together with sex and country, on performance in the Boston Marathon from 1972 to 2018. Different groups and subgroups of performance level were considered such as all runners, near elite 101:200 finishers, near elite 21:100, annual top ten finishers and annual winners. The main findings were . It was well-known that there was a progressive slowing of marathon performance as the ambient temperature increased from 5 \u00b0C to 25 \u00b0C [A first important finding was that increasing temperature was related to impaired performance in almost all groups of runners (to 25 \u00b0C . For thito 25 \u00b0C . In conthttps://sciencing.com/temperature-affect-barometric-pressure-5013070.html).A second important finding was that increasing barometric pressure worsened running performance. Most likely the increased barometric pressure is linked to an increased ambient temperature which is known to impair marathon running performance. Warm air causes air pressure to rise and American marathon races from 2001 to 2010 through with 1,791,972 participants\u2019 performances were analyzed, atmospheric pressure at sea level showed no effect on running performance [However, when the results of six European (www.weather.gov/tsa/wbgt). Little is known for the effect of wet-bulb globe temperature on marathon running performance. Ely et al. [i.e. Boston, New York, Twin Cities, Grandma\u2019s, Richmond, Hartford, and Vancouver Marathons) for a different range of years (i.e. 6 to 36 years) and different quartiles based on wet-bulb globe temperature and female and male finishers of different performance levels were analysed. The most likely explanation for the different findings is the fact that we analyzed a point-to-point race where wind might have a different effect on wet-bulb globe temperature compared to race held in one or several laps. Based on these disparate findings, future studies need to investigate more deeply the relationships between wet-bulb globe temperature and marathon running performance in other marathon races held in one or more laps.A third important finding was that an increase in wet-bulb globe temperature was related to a worsened performance in all groups except annual winners.Wet-bulb globe temperature is nowadays the most widely used index of heat stress in direcy et al. reportedi.e. wind from W, WNW, and WSW) improved race performance of all groups and increasing wind speed was also related to worsened performances for all finishers and near elite groups. Boston is a \u2018point-to-point\u2019 marathon from west to east (www.baa.org/races/boston-marathon/course-map). When the runners have a tailwind, they get a \u2018push\u2019 for 42 km. It is well-known for this race that headwinds on the day of the race slow winning times [A further important finding was that tail wind to 00:41:51 h:min:sec (top 101:200 finishers). Differences between countries and sexes in all finishers, compared to the other selection groups, were relatively smaller. For instance, the interaction term USA:M reduced the comparison Kenya-Ethiopia and USA, for men, by 00:11:59 h:min:sec. This term was almost twice the respective term in annual winners group (00:06:07 h:min:sec). But in all finishers, the performance difference Kenya-Ethiopia and USA was of 01:36:43 h:min:sec, compared to 00:06:30 h:min:sec in the winners group. Therefore, the effect in the winners was greater.e.g. topography, temperature) and participation . Thus, they should be generalized with caution to other marathon races. Future studies would be needed to confirm these findings in other large city marathons. Moreover, no information about age was available and repeated measurements within runners could not be exactly identified, although it could be reasonably supposed that two observations belonged to the same runner if they had in common both name, surname, sex, country and participation, once a year, in the same period of time.The findings of the present study were limited by the specific characteristics of this race in terms of environmental conditions and the qualifying standards could favour one sex and/or age group over the other. It was generally regarded that it was easier for women to qualify for Boston Marathon than men, which might influence the results. Although qualification criteria exist, about 10,000 runners participated annually on sponsor loyalties. Most likely, the number of this latter group of runners has increased most over the year, whilst qualifiers were stable over the years. It could be expected that the qualified age-groupers would perform better than their free-entry counterparts; however, with this information not available this speculative hypothesis could not be tested critically.It should be also mentioned that Boston Marathon was the only large city marathon in the World with \u2018qualifying times\u2019 Click here for additional data file.S1 File(R)Click here for additional data file.S1 Table(DOCX)Click here for additional data file.S1 FigPoints were observed average of time race. Lines were fitted curves.(TIF)Click here for additional data file."} +{"text": "Correction to: Journal for ImmunoTherapy of Cancer (2019) 7:15https://doi.org/10.1186/s40425-018-0472-1Following publication of the original article , the autThe correct files Additional file 2:Code and data for the validation dataset analyses. The R code and data used in the colorectal and endometrial/neuroendocrine validation analyses are included in this zip file. Code executes in the directory in which it is placed. (ZIP 456\u2009kb)"} +{"text": "AbstractRuehssiawoodburyana (Apocynaceae) was recently discovered at a single location on Norman Island in the British Virgin Islands. Despite an increase in the extent of occurrence and area of occupancy, this species meta-population is very limited with a total of 37 individuals known in the wild. The largest subpopulation, on Mona Island, has only 26 individuals. The species suitable habitat is experiencing a continuing decline due to urban development, grazing by feral ungulates and human-induced forest fires. Conservation action is urgently needed and should be directed towards establishing genetically representative ex situ collections, such as seed for long term storage and live material for propagation. This species is evaluated as Critically Endangered (CR), based on Criteria C2a(i)+D, according to the IUCN Red List Categories and Criteria (version 3.1) and guidelines (Thought to be endemic to the Commonwealth of Puerto Rico, idelines .Ruehssiawoodburyana on Norman Island, in the British Virgin Islands and discuss the species conservation status. Marsdeniawoodburyana is transferred to the genus Ruehssia to reflect the resurrection of that genus for species of Marsdenia native to the New World.Extensive and regular surveys to the region enable the discovery of new plant records for different countries and islands. In this paper, we record a new island record for In this paper, we present a species conservation profile for an endemic species to the British Virgin Islands and to the Commonwealth of Puerto Rico.RuehssiawoodburyanaScientific name: Species authority: (Acev.-Rodr) GoyderMarsdeniawoodburyana Acev.-Rodr., 1999 \u2013 Synonyms: PlantaeKingdom: TracheophytaPhylum: MagnoliopsidaClass: GentianalesOrder: ApocynaceaeFamily: Marsdenia R.Br. (Apocynaceae: Asclepiadoideae) occur in a single clade, according to a recent study using two plastid and two nuclear gene regions and it is planned to transfer species from other parts of the Americas in subsequent papers.In order to expedite the range extension of M.woodburyana Acev.-Rodr. to the British Virgin Islands and to permit timely publication of its conservation status, we here propose the formal transfer of this species from Marsdenia to Ruehssia.Ruehssiawoodburyana (Acev.-Rodr.) Goyder, comb. nov.BASIONYM: Marsdeniawoodburyana Acev.-Rodr., 1999 \u2013 Taxonomic notes: All the native New World species of the broadly delimited pan-tropical genus regions . The genRegion for assessment: GlobalReviewers: Clubbe, C.; Urbaniak, J.Editor: Barrios, S.; Hamilton, M.A.Reviewers: Clubbe, C.; Urbaniak, J.Editor: Barrios, S.; Hamilton, M.A.Biogeographic realm: NeotropicalCountries: Virgin Islands, BritishPuerto RicoMap of records (image): Map of records (Google Earth): Basis of EOO and AOO: ObservedBasis (narrative): Observed occurrences.Min Elevation/Depth (m): 10Max Elevation/Depth (m): 150Ruehssiawoodburyana is a rare plant species restricted to the Commonwealth of Puerto Rico and the British Virgin Islands (BVI). This species was originally described occurring exclusively at Ca\u00f1a Gorda within the Gu\u00e1nica State Forest in Gu\u00e1nica municipality on the island of Puerto Rico (R.woodburyana (O. Monsegur pers. comm. 2017). This species extent of occurrence (EOO) was estimated to be 5,649 km2 and the area of occupancy to be 32 km2 based on a 2\u00d72 km cell size : 5649Trend: IncreaseCauses ceased?: UnknownCauses understood?: UnknownCauses reversible?: UnknownExtreme fluctuations?: NoTrend: IncreaseCauses ceased?: UnknownCauses understood?: UnknownCauses reversible?: UnknownExtreme fluctuations?: NoAOO (km2): 32Number of locations: 7-8Justification for number of locations: The number of locations was calculated to be seven to eight, considering threats posed by human disturbance and human-induced fires at the different sites where the species has been recorded.Trend: UnknownExtreme fluctuations?: NoNumber of individuals: 37Trend: UnknownCauses ceased?: UnknownCauses understood?: UnknownCauses reversible?: UnknownExtreme fluctuations?: UnknownPopulation Information (Narrative): Originally described from Gu\u00e1nica State Forest as extremely rare, Abundance largest subpopulation: 26Number of subpopulations: 4Trend: UnknownExtreme fluctuations?: NoSevere fragmentation?: NoSystem: TerrestrialHabitat specialist: UnknownHabitat (narrative): A woody vine which can grow to eight metres long in tropical dry forest Figs . This spTrend in extent, area or quality?: Decline (observed)Habitat importance: Major ImportanceHabitats: 1.5. Forest - Subtropical/Tropical DryHabitat importance: Major ImportanceHabitats: 1.5. Forest - Subtropical/Tropical DryGeneration length (yr): 0Dependency of single sp?: NoEcology and traits (narrative): The generation length of this vine is unknown. More field observations are required.Justification for threats: This species is subjected to a variety of threats. Most locations are threatened by human disturbance which is causing habitat degradation and fragmentation, particularly through urban development and fire. In Puerto Rico, human-induced fires are frequent in Gu\u00e1nica State Forest along road PR 333 near Ca\u00f1a Gorda, the type locality. These seriously affect the quality of this species suitable habitat and may preclude the species natural recruitment. The habitat on Norman Island in the BVI was degraded by feral animals in the past, but these have now been removed, promoting the recovery of native vegetation. Despite the presence of feral goats and pigs on Mona Island, these animals are not thought to be impacting the species as feral mammal populations are managed through sports hunting. However, it is noted that no recruitment has been observed at this location in the recent years (J. Sustache pers. comm. 2018). At Laguna Cartagena and Cabo Rojo National Wildlife Refuges, there is no direct evidence of impact due to human-induced fires or feral animals, despite the presence of these threats. Within the municipality of Pe\u00f1uelas, this species suitable habitat is threatened by the expansion of industrial landfills, service roads and utility lines (O. Monsegur pers. comm. 2018). Climate change might already be impacting this species through more severe droughts and stronger tropical storms.Threat type: OngoingThreats: 1.3. Residential & commercial development - Tourism & recreation areas4.1. Transportation & service corridors - Roads & railroads4.2. Transportation & service corridors - Utility & service lines7.1. Natural system modifications - Fire & fire suppression11.2. Climate change & severe weather - DroughtsThreat type: OngoingThreats: 1.3. Residential & commercial development - Tourism & recreation areas4.1. Transportation & service corridors - Roads & railroads4.2. Transportation & service corridors - Utility & service lines7.1. Natural system modifications - Fire & fire suppression11.2. Climate change & severe weather - Droughtsex situ collections for this species despite attempts in recent years to collect seed from southern municipalities on the island of Puerto Rico (J. Sustache pers. comm. 2018).Justification for conservation actions: This species is found within protected areas across its natural range. In the Commonwealth of Puerto Rico, the species is recorded as occurring within the Gu\u00e1nica State Forest, Laguna Cartagena National Wildlife Refuge, Cabo Rojo National Wildlife Refuge and Mona Island Nature Reserve. It is also thought to occur within the Culebra National Wildlife Reserve, but further surveys are needed. Norman Island in the BVI is not a protected area, as it is privately owned. This species is listed as a Critical Element by the Department of Natural and Environmental Resources . MonseguConservation action type: NeededConservation actions: 1.2. Land/water protection - Resource & habitat protection3.4. Species management - Ex-situ conservation4.3. Education & awareness - Awareness & communicationsConservation action type: NeededConservation actions: 1.2. Land/water protection - Resource & habitat protection3.4. Species management - Ex-situ conservation4.3. Education & awareness - Awareness & communicationsJustification for use and trade: There are no known uses for this species.Justification for ecosystem services : Insufficient Information availableUse type: InternationalEcosystem service type: Less importantResearch needed: 1.2. Research - Population size, distribution & trends1.3. Research - Life history & ecology3.4. Monitoring - Habitat trendsex situ conservation collections. Further surveys are needed to look for potential undetected individuals and subpopulations within the species range, particularly in the US and British Virgin Islands. The areas and habitats, where this species occurs, should be closely managed and monitored.Justification for research needed: Conservation action and research should be directed to develop a better understanding of this species' ecology and population trends and develop Use type: InternationalEcosystem service type: Less importantResearch needed: 1.2. Research - Population size, distribution & trends1.3. Research - Life history & ecology3.4. Monitoring - Habitat trendsex situ conservation collections. Further surveys are needed to look for potential undetected individuals and subpopulations within the species range, particularly in the US and British Virgin Islands. The areas and habitats, where this species occurs, should be closely managed and monitored.Justification for research needed: Conservation action and research should be directed to develop a better understanding of this species' ecology and population trends and develop 6355BA10-D648-52AF-8F97-9E52B988512B10.3897/BDJ.7.e47110.suppl1Supplementary material 1Ruehssiawoodburyana known recordsGoogle Earth map showing Data type: occurencesFile: oo_307399.kmlhttps://binary.pensoft.net/file/307399Barrios, S.; Hamilton, H.; Monsegur, O.; Sustache, J."} +{"text": "Medical Law Review, 2019, doi:10.1093/medlaw/fwz009In the original version of this article, the following funding acknowledgement was mistakenly omitted:http://www.i-sense.org.uk>).James Wilson's research was supported by the i\u2010sense EPSRC IRC in Early Warning Sensing Systems for Infectious Diseases (Grant reference number EP/K031953/1,