"I was originally prescribed this for Major Depressive Disorder and Generalised Anxiety Disorder. At 20mg it didn't help at all, but once raised to 40mg and combined with an anti-psychotic (to prevent manic episodes) it worked well for 5 - 6 months.



Unfortunately it stopped working completely, quite out of the blue, and neither myself, other half or medical professionals could figure out why. It was a shame as  I had virtually no side-effects on this medication, just some 'bruxing' (teeth grinding) at night, but not to the point where my jaw ached or anything."