"I take 0.75 mg at 6.00pm. This totally relieves restless legs syndrome for me. Side effects are mild but include profound sleepiness and mildly heightened libido (true!) which are somewhat self-defeating. Because Requip is a dopamine agonist it works alongside iron as a co-factor. Therefore, I need to minimise iron-depleting lifestyle factors as well as taking Requip. That means that I can only have de-caffeineated coffee and that I can't drink alcohol. "