"i found this thread after administering monistat OTC (7 day, brand name) for the first dose and experiencing severe burning sensation.  it was pretty awful and lasted almost an hour.  i had been given monistat by prescription (before it was available OTC) many years ago (like 30) and don't remember it burning at all, so i was taken by unpleasant surprise.



i was very concerned about the second dose after reading all the posts here, but, the first did help with the symptoms of the yeast infection; the worst was the constant need to pee and being unable to do so.



so the second night i went ahead and used a second dose and in my case, it was much more tolerable.  same with day 3 (tonight), barely any burn at all.  and i can pee again."