DerAnaesthesist.80470330.ger.abstr-passage-0
abstract
Hydroxyaethylstaerke ( HAES und Dextran ( ) DX ) werden neben ihrer renalen und gastrointestinalen Ausscheidung und ihrem enzymatischen Abbau ( Amylase ; Dextranase ) zu einem kleinen Prozentsatz in den Zellen des retikuloendothelialen Systems ( RES ) der Leber , Lunge , Milz und den Lymphknoten gespeichert . Diese Speicherung ist zeitlich begrenzt , von der verwendeten Loesung und von individuellen Faktoren ( Lysosomen ) abhaengig und klinisch im allgemeinen ohne Relevanz . Wir berichten von einem Patienten mit akutem Lungenversagen ( ARDS ) und Sepsis , bei dem es im Rahmen der Anwendung von HAES mit einem Molekulargewicht ( MG ) von 450000 Dalton ( D und DX ( ) MG 40000 und 70000 D ) zu einer Ueberladung des RES mit diesen nur langsam abbaubaren Substanzen gekommen ist . Durch die Speicherung der Kolloide bedingte Nebenwirkungen im Sinne eines massiven Alveolarzellkatarrhs mit Austamponierung der Alveolen , einer Hypertrophie der von Kupfferschen Sternzellen , eines Auseinanderdraengens der Leberzellbalken und einer osmotischen Nephrose sowie deren moegliche Relation zu respiratorischer- , Leber- und Niereninsuffizienz werden diskutiert und anhand von Literaturstellen aufgearbeitet .
DerAnaesthesist.80470330.ger.abstr-s1-r1-t3.1-t4.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s1-r2-t3.1-t2.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s1-r3-t3.1-t6.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s1-r4-t1.1-t5.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s1-r5-t2.1-t9.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t9
DerAnaesthesist.80470330.ger.abstr-s1-r6-t5.1-t9.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t9
DerAnaesthesist.80470330.ger.abstr-s1-r7-t5.1-t8.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s1-r8-t1.1-t3.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s1-r9-t3.1-t5.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s1-r10-t4.1-t9.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t9
DerAnaesthesist.80470330.ger.abstr-s1-r11-t4.1-t2.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s1-r12-t2.1-t8.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s1-r13-t5.1-t7.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s1-r14-t4.1-t8.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s1-r15-t2.1-t3.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s1-r16-t2.1-t7.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s1-r17-t5.1-t6.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s1-r18-t2.1-t1.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s1-r19-t4.1-t7.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s1-r20-t2.1-t6.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s1-r21-t5.1-t4.1
produces
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s1-r22-t1.1-t9.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t9
DerAnaesthesist.80470330.ger.abstr-s1-r23-t3.1-t1.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s1-r24-t4.1-t6.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s1-r25-t2.1-t5.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s1-r26-t1.1-t4.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s1-r27-t5.1-t3.1
produces
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s1-r28-t3.1-t9.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t9
DerAnaesthesist.80470330.ger.abstr-s1-r29-t4.1-t3.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s1-r30-t1.1-t8.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s1-r31-t1.1-t2.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s1-r32-t4.1-t1.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s1-r33-t4.1-t5.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s1-r34-t5.1-t2.1
produces
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s1-r35-t3.1-t8.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s1-r36-t2.1-t4.1
interacts_with
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s1-r37-t1.1-t7.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s1-r38-t5.1-t1.1
produces
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s1-r39-t3.1-t7.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s1-r40-t1.1-t6.1
disrupts
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s3-r1-t2.1-t3.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s3-r2-t3.1-t1.1
occurs_in
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s3-r3-t3.2-t1.1
occurs_in
DerAnaesthesist.80470330.ger.abstr-s3-t3
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s3-r4-t3.1-t3.2
associated_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s3-t3
DerAnaesthesist.80470330.ger.abstr-s3-r5-t2.1-t3.2
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s3-t3
DerAnaesthesist.80470330.ger.abstr-s3-r6-t3.2-t3.1
associated_with
DerAnaesthesist.80470330.ger.abstr-s3-t3
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r1-t2.1-t7.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r2-t8.1-t3.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r3-t3.1-t5.1
degree_of
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r4-t1.1-t3.1
affects
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r5-t4.1-t8.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s4-r6-t3.1-t7.1
associated_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r7-t2.1-t5.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r8-t3.1-t5.1
associated_with
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r9-t4.1-t7.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r10-t2.1-t4.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-r11-t4.1-t6.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s4-r12-t5.1-t3.1
result_of
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r13-t2.1-t3.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r14-t4.1-t5.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r15-t6.1-t7.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r16-t1.1-t7.1
affects
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r17-t5.1-t3.1
degree_of
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r18-t7.1-t3.1
result_of
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r19-t4.1-t3.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r20-t5.1-t3.1
associated_with
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r21-t1.1-t3.1
causes
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r22-t6.1-t5.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r23-t7.1-t3.1
degree_of
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r24-t4.1-t2.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-t2
DerAnaesthesist.80470330.ger.abstr-s4-r25-t8.1-t7.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r26-t6.1-t4.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-r27-t3.1-t7.1
result_of
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r28-t1.1-t5.1
affects
DerAnaesthesist.80470330.ger.abstr-s4-t1
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r29-t6.1-t3.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t6
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-r30-t3.1-t7.1
degree_of
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-r31-t8.1-t5.1
location_of
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r32-t8.1-t4.1
adjacent_to
DerAnaesthesist.80470330.ger.abstr-s4-t8
DerAnaesthesist.80470330.ger.abstr-s4-t4
DerAnaesthesist.80470330.ger.abstr-s4-r33-t3.1-t5.1
result_of
DerAnaesthesist.80470330.ger.abstr-s4-t3
DerAnaesthesist.80470330.ger.abstr-s4-t5
DerAnaesthesist.80470330.ger.abstr-s4-r34-t7.1-t3.1
associated_with
DerAnaesthesist.80470330.ger.abstr-s4-t7
DerAnaesthesist.80470330.ger.abstr-s4-t3