DerAnaesthesist.80470538.ger.abstr-passage-0
abstract
Das angeborene ( unspezifische ) und das erworbene ( spezifische ) Immunsystem sind unter den Defensiv- und Reparatursystemen des Koerpers von zentraler Bedeutung . Schmerz Stress , nekrotisches Gewebe und eindringende Mikroorganismen , haben komplexe Einfluesse auf die Immunantwort des chirurgischen Patienten , die vielfach durch anaesthesiologische Massnahmen - bis weit in die postoperative Phase - moduliert wird . Beispiele hierfuer sind die Transfusion von Blut- oder Blutprodukten , aber auch die perioperative Gabe von Dopamin oder Metoclopramid . Persistierender Schmerz geht im Tierexperiment mit Immuntoleranz , Infektanfaelligkeit und Tumorprogression einher . Anaesthetika beeinflussen dabei ueber eine Daempfung der neurohumoralen Stressantwort , aber auch direkt durch Interaktion mit immunkompetenten Zellen die perioperative Funktion des Immunsystems . Eine adaequate Analgesie verbessert die Immunkompetenz des gestressten Individuums , wobei insbesondere die peridurale und spinale Opioidanwendung guenstige Effekte aufzuweisen scheinen . Einzelne Anaesthetika wie Etomidat , Propofol oder Thiobarbiturate und auch die Opioide koennen darueber hinaus - zum Teil jedoch nur bei protrahierter Exposition oder in supraklinischen Konzentrationen - direkt verschiedene Funktionen immunkompetenter Effektorzellen wie Bakterizidie , Proliferation oder Zytokinantwort beeinflussen . Waehrend klinische Studien auf eine Zunahme der Inzidenz nosokomialer Infektionen bei Barbituratsedierung neurochirurgischer Patienten hinweisen , liegen Befunde zum Einfluss des gewaehlten Anaesthesieverfahrens auf die postoperative Inzidenz infektioeser Komplikationen oder eine Tumorprogression im Rahmen onkologischer Eingriffe derzeit nicht vor .
DerAnaesthesist.80470538.ger.abstr-s2-r1-t1.1-t2.1
co-occurs_with
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s2-r2-t2.1-t1.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s2-r3-t1.1-t2.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s2-r4-t2.1-t4.1
occurs_in
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s2-r5-t2.1-t1.1
co-occurs_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s2-r6-t3.1-t2.1
location_of
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s3-r1-t2.2-t1.1
disrupts
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s3-r2-t1.1-t4.1
produces
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s3-r3-t1.1-t1.2
surrounds
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s3-r4-t1.2-t4.1
produces
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s3-r5-t2.2-t1.2
disrupts
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s3-r6-t4.1-t1.1
disrupts
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s3-r7-t1.1-t2.2
produces
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s3-r8-t4.1-t2.2
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s3-r9-t1.1-t2.2
surrounds
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s3-r10-t1.2-t2.2
produces
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s3-r11-t4.1-t1.2
disrupts
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s3-r12-t2.2-t4.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s3-r13-t1.2-t2.2
surrounds
DerAnaesthesist.80470538.ger.abstr-s3-t1
DerAnaesthesist.80470538.ger.abstr-s4-t2
DerAnaesthesist.80470538.ger.abstr-s4-r1-t4.1-t1.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s4-r2-t1.1-t3.1
evaluation_of
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s4-r3-t4.1-t3.1
result_of
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s4-r4-t3.1-t4.1
result_of
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s4-r5-t3.1-t2.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s4-r6-t4.1-t2.1
occurs_in
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s4-r7-t4.1-t2.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s4-r8-t1.1-t4.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s5-r1-t1.1-t2.1
diagnoses
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s5-r2-t3.1-t4.1
conceptual_part_of
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s5-r3-t3.1-t2.1
location_of
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s5-r4-t1.1-t3.1
disrupts
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s6-r1-t2.1-t1.1
precedes
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s7-r1-t5.1-t4.1
produces
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s7-r2-t3.1-t2.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s7-r3-t4.1-t5.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r4-t3.1-t1.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s7-r5-t2.1-t6.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s7-r6-t5.1-t3.1
produces
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s7-r7-t4.1-t3.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s7-r8-t3.1-t6.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s7-r9-t4.1-t2.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s7-r10-t4.1-t6.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s7-r11-t2.1-t5.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r12-t4.1-t1.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s7-r13-t5.1-t4.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s7-r14-t5.1-t6.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s7-r15-t5.1-t2.1
produces
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s7-r16-t2.1-t5.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r17-t5.1-t3.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s7-r18-t3.1-t5.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r19-t2.1-t3.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s7-r20-t5.1-t2.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s7-r21-t4.1-t5.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r22-t5.1-t1.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s7-r23-t5.1-t6.1
location_of
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s7-r24-t3.1-t5.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s7-r25-t2.1-t1.1
interacts_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-r1-t5.1-t7.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-r2-t2.1-t5.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-r3-t4.1-t5.1
performs
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-r4-t3.1-t7.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-r5-t1.1-t5.1
conceptual_part_of
DerAnaesthesist.80470538.ger.abstr-s8-t1
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-r6-t7.1-t4.1
occurs_in
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-r7-t5.1-t4.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-r8-t5.1-t2.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-r9-t6.1-t5.1
conceptual_part_of
DerAnaesthesist.80470538.ger.abstr-s8-t6
DerAnaesthesist.80470538.ger.abstr-s8-t5
DerAnaesthesist.80470538.ger.abstr-s8-r10-t2.1-t4.1
occurs_in
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t4
DerAnaesthesist.80470538.ger.abstr-s8-r11-t2.1-t7.1
degree_of
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-r12-t7.1-t2.1
degree_of
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-r13-t3.1-t2.1
affects
DerAnaesthesist.80470538.ger.abstr-s8-t3
DerAnaesthesist.80470538.ger.abstr-s8-t2
DerAnaesthesist.80470538.ger.abstr-s8-r14-t7.1-t5.1
associated_with
DerAnaesthesist.80470538.ger.abstr-s8-t7
DerAnaesthesist.80470538.ger.abstr-s8-t5