DerChirurg.70680116.ger.abstr-passage-0
abstract
Zusammenfassung . Das Insulinom ist ein seltener Tumor und betrifft 90 % der endokrinen Pankreastumoren . Grundlage des Hyperinsulinismus ist typischerweise ein solitaerer Tumor , in jeweils 10 % multiple Tumoren ( z . B. multiple endokrine Neoplasie Typ I ) und malignes Insulinom sowie selten die Nesidioblastose oder Inselzelladenomatose . Wegweisend ist die klinische Symptomatik mit Neuroglucopenie , beweisend die inadaequat hohe Insulin- und C-Peptidsekretion bei Hypoglykaemie im Hungertest . Praeoperative Lokalisationsdiagnostik beim Ersteingriff ist obsolet . Standardoperation ist die Enucleation des Tumors oder in Abhaengigkeit von Groesse und Lage die Resektion . Problematisch ist die Behandlung von multiplen Tumoren und Inselzellhyperplasie , die mit einer hohen Rezidivrate belastet sind . Subtotale Resektion plus Enucleation scheinen selektiver Tumorentfernung ueberlegen . Beim malignen Insulinom , meist mit Lebermetastasen , stehen aggressive chirurgische Therapie mit Leberresektion und Debulking , Chemoembolisation und systemische Chemotherapie zur Wahl .
DerChirurg.70680116.ger.abstr-s3-r1-t2.1-t1.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s3-r2-t1.1-t3.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s3-r3-t1.1-t2.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s3-r4-t3.1-t1.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s4-r1-t2.1-t3.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s4-r2-t1.1-t3.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s4-r3-t3.1-t2.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s4-r4-t3.1-t1.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s5-r1-t1.1-t2.1
affects
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s5-r2-t1.1-t2.1
diagnoses
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s5-r3-t2.1-t1.1
produces
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s5-r4-t2.1-t3.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s5-r5-t3.1-t2.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s5-r6-t3.1-t1.1
produces
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s5-r7-t1.1-t3.1
affects
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s5-r8-t2.1-t3.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s5-r9-t1.1-t3.1
diagnoses
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s5-r10-t1.1-t3.1
treats
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s5-r11-t3.1-t2.1
degree_of
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s8-r1-t3.1-t2.1
result_of
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s8-r2-t2.1-t3.1
result_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s8-r3-t2.1-t1.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s8-r4-t1.1-t2.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-r1-t3.2-t1.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-r2-t4.2-t3.2
location_of
DerChirurg.70680116.ger.abstr-s10-t4
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r3-t2.1-t1.1
location_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-r4-t2.1-t6.1
location_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t6
DerChirurg.70680116.ger.abstr-s10-r5-t3.1-t6.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-t6
DerChirurg.70680116.ger.abstr-s10-r6-t4.2-t3.1
location_of
DerChirurg.70680116.ger.abstr-s10-t4
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r8-t2.1-t3.2
location_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r9-t6.1-t3.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t6
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r10-t1.1-t6.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t6
DerChirurg.70680116.ger.abstr-s10-r11-t6.1-t1.1
associated_with
DerChirurg.70680116.ger.abstr-s10-t6
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-r12-t4.2-t1.1
location_of
DerChirurg.70680116.ger.abstr-s10-t4
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-r13-t1.1-t3.2
associated_with
DerChirurg.70680116.ger.abstr-s10-t1
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r14-t2.1-t3.1
location_of
DerChirurg.70680116.ger.abstr-s10-t2
DerChirurg.70680116.ger.abstr-s10-t3
DerChirurg.70680116.ger.abstr-s10-r15-t4.2-t6.1
location_of
DerChirurg.70680116.ger.abstr-s10-t4
DerChirurg.70680116.ger.abstr-s10-t6