Clinically significant abnormalities of glucose metabolism 
Spinal cord compression or brain metastases unless asymptomatic, treated and stable (not requiring steroids) 
Evidence of severe or uncontrolled systemic diseases, including active bleeding diatheses or active infections including hepatitis B, C and Human Immunodeficiency Virus (HIV) 
Evidence of clinically significant cardiac abnormalities, uncontrolled hypotension, left ventricular ejection fraction below the lower limit of normal for the site or experience of significant cardiac interventional procedures 
A bad reaction to AZD5363 or any drugs similar to it in structure or class       
    

NCT01895946_exc_T1
Qualifier
Clinically significant
NCT01895946_exc_T2
Condition
abnormalities of glucose metabolism
NCT01895946_exc_T3
Condition
Spinal cord compression
NCT01895946_exc_T4
Condition
brain metastases
NCT01895946_exc_T5
Condition
asymptomatic
NCT01895946_exc_T6
Negation
unless
NCT01895946_exc_T7
Qualifier
treated
NCT01895946_exc_T8
Qualifier
stable
NCT01895946_exc_T9
Scope
asymptomatic, treated and stable (not requiring steroids)
NCT01895946_exc_T10
Drug
steroids
NCT01895946_exc_T11
Negation
not
NCT01895946_exc_T12
Scope
Spinal cord compression or brain metastases
NCT01895946_exc_T13
Qualifier
uncontrolled
NCT01895946_exc_T14
Condition
systemic diseases
NCT01895946_exc_T15
Qualifier
severe
NCT01895946_exc_T16
Scope
severe or uncontrolled
NCT01895946_exc_T17
Condition
active bleeding diatheses
NCT01895946_exc_T18
Condition
active infections
NCT01895946_exc_T19
Condition
hepatitis B
NCT01895946_exc_T20
Condition
Human Immunodeficiency Virus (HIV)
NCT01895946_exc_T21
Condition
hepatitis C
NCT01895946_exc_T22
Scope
hepatitis B, C and Human Immunodeficiency Virus (HIV)
NCT01895946_exc_T23
Scope
active bleeding diatheses or active infections including hepatitis B, C and Human Immunodeficiency Virus (HIV)
NCT01895946_exc_T24
Qualifier
clinically significant
NCT01895946_exc_T26
Condition
cardiac abnormalities
NCT01895946_exc_T27
Condition
uncontrolled hypotension
NCT01895946_exc_T28
Measurement
left ventricular ejection fraction
NCT01895946_exc_T29
Value
below the lower limit of normal
NCT01895946_exc_T30
Procedure
cardiac interventional procedures
NCT01895946_exc_T31
Qualifier
significant
NCT01895946_exc_T33
Condition
bad reaction to AZD5363
NCT01895946_exc_T34
Drug
AZD5363