1. Unable to ambulate at least 150 feet prior to stroke, or experienced intermittent claudication while walking; 
2. history of congestive heart failure, unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's; 
3. History of oxygen dependence; 
4. Preexisting neurological disorders, dementia or previous stroke; 
5. History of major head trauma; 
6. Legal blindness or severe visual impairment; 
7. history of psychosis or other Axis I disorder that is primary; 
8. Life expectancy <1 yr.; 
9. Severe arthritis or other problems that limit passive range of motion; 
10. History of DVT or pulmonary embolism within 6 months; 
11. Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions; 
12. Severe hypertension with systolic >200 mmHg and diastolic >110 mmHg at rest; 
13. attempt of suicide in the last 2 years or at suicidal risk assessed by SCID interview; 
14. Previous or current enrollment in a clinical trial to enhance motor recovery; 15) currently exercising ≥ 2 times per week (≥20 minutes); 
16) Presence of non-MR compatible implants, pregnancy or severe claustrophobia.       
    

NCT03056287_exc_T16
Condition
Unable to ambulate at least 150 feet
NCT03056287_exc_T17
Temporal
prior
NCT03056287_exc_T18
Condition
stroke
NCT03056287_exc_T19
Reference_point
stroke
NCT03056287_exc_T20
Condition
intermittent claudication
NCT03056287_exc_T21
Qualifier
while walking
NCT03056287_exc_T22
Observation
history
NCT03056287_exc_T23
Condition
congestive heart failure
NCT03056287_exc_T24
Condition
unstable cardiac arrhythmias
NCT03056287_exc_T25
Condition
hypertrophic cardiomyopathy
NCT03056287_exc_T26
Condition
severe aortic stenosis
NCT03056287_exc_T27
Condition
angina
NCT03056287_exc_T28
Condition
dyspnea at rest
NCT03056287_exc_T29
Condition
dyspnea during ADL's
NCT03056287_exc_T30
Scope
congestive heart failure, unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's
NCT03056287_exc_T31
Condition
oxygen dependence
NCT03056287_exc_T32
Observation
History
NCT03056287_exc_T33
Condition
neurological disorders
NCT03056287_exc_T34
Condition
dementia
NCT03056287_exc_T35
Condition
stroke
NCT03056287_exc_T36
Temporal
previous
NCT03056287_exc_T37
Temporal
Preexisting
NCT03056287_exc_T38
Condition
major head trauma
NCT03056287_exc_T39
Observation
History
NCT03056287_exc_T40
Condition
severe visual impairment
NCT03056287_exc_T41
Condition
Legal blindness
NCT03056287_exc_T42
Condition
psychosis
NCT03056287_exc_T43
Condition
Axis I disorder
NCT03056287_exc_T44
Qualifier
primary
NCT03056287_exc_T45
Observation
history
NCT03056287_exc_T46
Observation
Life expectancy
NCT03056287_exc_T47
Value
<1 yr
NCT03056287_exc_T48
Condition
Severe arthritis
NCT03056287_exc_T49
Condition
problems that limit passive range of motion
NCT03056287_exc_T51
Condition
DVT
NCT03056287_exc_T52
Condition
pulmonary embolism
NCT03056287_exc_T53
Temporal
within 6 months
NCT03056287_exc_T54
Observation
History
NCT03056287_exc_T55
Scope
DVT or pulmonary embolism within 6 months
NCT03056287_exc_T56
Condition
diabetes
NCT03056287_exc_T57
Qualifier
Uncontrolled
NCT03056287_exc_T58
Condition
weight loss
NCT03056287_exc_T59
Condition
diabetic coma
NCT03056287_exc_T60
Condition
insulin reactions
NCT03056287_exc_T61
Multiplier
frequent
NCT03056287_exc_T62
Condition
Severe hypertension
NCT03056287_exc_T63
Measurement
systolic
NCT03056287_exc_T64
Value
>200 mmHg
NCT03056287_exc_T65
Measurement
diastolic
NCT03056287_exc_T66
Value
>110 mmHg
NCT03056287_exc_T67
Condition
attempt of suicide
NCT03056287_exc_T68
Temporal
in the last 2 years
NCT03056287_exc_T69
Condition
at suicidal risk
NCT03056287_exc_T70
Procedure
SCID interview
NCT03056287_exc_T73
Device
non-MR compatible implants
NCT03056287_exc_T74
Condition
pregnancy
NCT03056287_exc_T75
Condition
claustrophobia
NCT03056287_exc_T76
Qualifier
severe