1. Diagnosed with symptomatic sacral perineurial cysts(e.g., lumbosacral or perineal pain, fecal or urinary functions change, sexual function change, lower limb radiation pain, muscle abate, paresthesia, etc)
2. Visual analog scale more than or equal to 4
3. Signed the informed consent
4. Years, range 18-60
5. Self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores < 50
6. No Congenital,Mental and other Nervous system diseases
7. No Serious Cardiac,Pulmonary,Hepatic and Nephritic disease
8. No history of drug allergy
9. No pain(including dysmenorrhea) or drug use (e.g., antipyretics,sleeping pills) within the last month
10. MRI finding of sacral perineurial cysts, but without any clinical symptoms, included in the negative control group
11. MRI finding healthy volunteers don't have sacral perineurial cysts, included in the negative control groupblank control group

NCT02595190_inc_T1
Condition
sacral perineurial cysts(
NCT02595190_inc_T2
Qualifier
symptomatic
NCT02595190_inc_T3
Condition
perineal pain
NCT02595190_inc_T4
Condition
lumbosacral pain
NCT02595190_inc_T5
Condition
urinary functions change
NCT02595190_inc_T6
Condition
functions change, fecal
NCT02595190_inc_T7
Condition
sexual function change
NCT02595190_inc_T8
Condition
lower limb radiation pain
NCT02595190_inc_T9
Condition
muscle abate
NCT02595190_inc_T10
Condition
paresthesia
NCT02595190_inc_T11
Scope
lumbosacral or perineal pain, fecal or urinary functions change, sexual function change, lower limb radiation pain, muscle abate, paresthesia
NCT02595190_inc_T12
Measurement
Visual analog scale
NCT02595190_inc_T13
Value
more than or equal to 4
NCT02595190_inc_T15
Person
Years
NCT02595190_inc_T16
Value
18-60
NCT02595190_inc_T17
Measurement
Self-rating anxiety scale
NCT02595190_inc_T18
Measurement
SAS
NCT02595190_inc_T19
Measurement
self-rating depression scale
NCT02595190_inc_T20
Measurement
SDS
NCT02595190_inc_T21
Value
scores < 50
NCT02595190_inc_T22
Scope
Self-rating anxiety scale (SAS) and self-rating depression scale (SDS
NCT02595190_inc_T23
Condition
Nervous system diseases
NCT02595190_inc_T24
Negation
No
NCT02595190_inc_T25
Condition
nital,Ment ses
7. N
NCT02595190_inc_T26
Condition
l and ses
7.
NCT02595190_inc_T27
Scope
Congenital,Mental and other Nervous system disease
NCT02595190_inc_T28
Condition
Nephritic disease
NCT02595190_inc_T29
Condition
Hepatic
NCT02595190_inc_T30
Condition
Pulmonary
NCT02595190_inc_T31
Condition
Cardiac
NCT02595190_inc_T32
Condition
allergy
NCT02595190_inc_T33
Drug
drug
NCT02595190_inc_T34
Negation
No
NCT02595190_inc_T35
Negation
No
NCT02595190_inc_T36
Negation
No
NCT02595190_inc_T37
Condition
Cardiac,Pulmonary,Hepatic
NCT02595190_inc_T38
Condition
pain
NCT02595190_inc_T39
Temporal
last month
NCT02595190_inc_T40
Condition
dysmenorrhea
NCT02595190_inc_T41
Drug
drug