OAT required for reasons not related to AF (i.e., prosthetic valve, PV stenosis, previous pulmonary embolism, presence of spontaneous echo contrast [SEC] at standard echo performed at 3-months follow-up).
Any cardiac surgery within the past 60 days (2 months) or valvular cardiac surgical procedure at any time (i.e., ventriculotomy, atriotomy, and valve repair or replacement and presence of a prosthetic valve)
Previous myocardial infarction (MI) or a percutaneous coronary intervention PCI within the past 3 months
Awaiting cardiac transplantation or other cardiac surgery within the next 365 days (12 months)
Documented left atrial thrombus
Significant pulmonary disease, (e.g., restrictive pulmonary disease, constrictive or COPD) or any other disease or malfunction of the lungs or respiratory system that produces chronic symptoms
Significant medical problem that in the opinion of the investigator would preclude enrollment in this study
Women who are pregnant (as evidenced by pregnancy test if pre-menopausal)
Acute illness or active systemic infection or sepsis
Unstable angina
Contraindication to anticoagulation (i.e., heparin, warfarin or another commercially available anticoagulation medication)
History of blood clotting or bleeding abnormalities
Life expectancy less than 360 days (12 months)
Uncontrolled Heart Failure or NYHA Class III or IV heart failure
Enrollment in a clinical study evaluating another device or drug, within the past 6 months
Unable or unwilling to comply with protocol requirements

NCT01959425_exc_T1
Drug
OAT
NCT01959425_exc_T2
Negation
not
NCT01959425_exc_T3
Qualifier
AF
NCT01959425_exc_T4
Device
prosthetic valve
NCT01959425_exc_T5
Condition
PV stenosis
NCT01959425_exc_T6
Condition
pulmonary embolism
NCT01959425_exc_T7
Measurement
standard echo
NCT01959425_exc_T8
Temporal
3-months follow-up
NCT01959425_exc_T9
Reference_point
follow-up
NCT01959425_exc_T10
Value
spontaneous echo contrast
NCT01959425_exc_T11
Value
SEC
NCT01959425_exc_T12
Scope
prosthetic valve, PV stenosis, previous pulmonary embolism, presence of spontaneous echo contrast [SEC] at standard echo performed at 3-months follow-up
NCT01959425_exc_T13
Procedure
cardiac surgery
NCT01959425_exc_T14
Temporal
within the past 60 days
NCT01959425_exc_T15
Temporal
2 months
NCT01959425_exc_T16
Procedure
valvular cardiac surgical
NCT01959425_exc_T17
Procedure
ventriculotomy
NCT01959425_exc_T18
Procedure
atriotomy
NCT01959425_exc_T19
Procedure
valve repair
NCT01959425_exc_T20
Procedure
alve eplacement
NCT01959425_exc_T21
Device
prosthetic valve)
NCT01959425_exc_T22
Scope
ventriculotomy, atriotomy, and valve repair or replacement and presence of a prosthetic valve
NCT01959425_exc_T23
Condition
myocardial infarction
NCT01959425_exc_T24
Condition
MI
NCT01959425_exc_T25
Procedure
percutaneous coronary intervention
NCT01959425_exc_T26
Procedure
PCI
NCT01959425_exc_T27
Temporal
within the past 3 months
NCT01959425_exc_T28
Scope
myocardial infarction (MI) or a percutaneous coronary intervention PCI
NCT01959425_exc_T29
Procedure
cardiac transplantation
NCT01959425_exc_T30
Mood
Awaiting
NCT01959425_exc_T31
Procedure
cardiac surgery
NCT01959425_exc_T32
Temporal
within the next 365 days
NCT01959425_exc_T33
Temporal
hin th months)
D
NCT01959425_exc_T34
Scope
cardiac transplantation or other cardiac surgery
NCT01959425_exc_T35
Condition
left atrial thrombus
NCT01959425_exc_T36
Condition
pulmonary disease
NCT01959425_exc_T37
Qualifier
Significant
NCT01959425_exc_T38
Condition
restrictive pulmonary disease
NCT01959425_exc_T39
Condition
COPD
NCT01959425_exc_T41
Scope
restrictive pulmonary disease, constrictive or COPD)
NCT01959425_exc_T44
Condition
systemic infection
NCT01959425_exc_T45
Condition
sepsis
NCT01959425_exc_T47
Condition
Unstable angina
NCT01959425_exc_T48
Condition
Contraindication
NCT01959425_exc_T49
Drug
anticoagulation
NCT01959425_exc_T50
Drug
heparin
NCT01959425_exc_T51
Drug
warfarin
NCT01959425_exc_T53
Scope
heparin, warfarin
NCT01959425_exc_T54
Condition
bleeding abnormalities
NCT01959425_exc_T55
Condition
ing or bleedin es
Life expec
NCT01959425_exc_T56
Observation
Life expectancy
NCT01959425_exc_T57
Value
less than 360 days
NCT01959425_exc_T58
Value
0 days (1 ncontroll
NCT01959425_exc_T59
Condition
Heart Failure
NCT01959425_exc_T60
Qualifier
Uncontrolled
NCT01959425_exc_T61
Condition
heart failure
NCT01959425_exc_T62
Qualifier
NYHA Class III
NCT01959425_exc_T63
Qualifier
I or IV he ur
NCT01959425_exc_T64
Scope
NYHA Class III or IV