previous brain surgery;
cognitive impairment (< 120 points on the Mattis Dementia Rating Scale)
moderate-to-severe depression (> 25 points on the Beck Depression Inventory)
marked brain atrophy as detected by magnetic resonance imaging
other medical or psychiatric coexisting disorders that could increase the surgical risk or interfere with completion of the trial

NCT01497639_exc_T1
Temporal
previous
NCT01497639_exc_T2
Procedure
brain surgery
NCT01497639_exc_T3
Condition
cognitive impairment
NCT01497639_exc_T4
Value
< 120 points
NCT01497639_exc_T5
Measurement
Mattis Dementia Rating Scale
NCT01497639_exc_T6
Qualifier
moderate-to-severe
NCT01497639_exc_T7
Condition
depression
NCT01497639_exc_T8
Value
> 25 points
NCT01497639_exc_T9
Measurement
Beck Depression Inventory
NCT01497639_exc_T10
Condition
brain atrophy
NCT01497639_exc_T11
Procedure
magnetic resonance imaging