Prior endobronchial treatment for emphysema 
Pleural or interstitial disease that precludes surgery. 
Prior lung transplant, LVRS, median sternotomy, bullectomy or lobectomy. 
Clinically significant bronchiectasis 
Pulmonary nodule requiring surgery 
History of recurrent respiratory infections (> 3 hospitalization in the last year) 
Clinically significant (> 4 Tablespoons per day) sputum production 
Fever, elevated white cell count, or other evidence of active infection 
Dysrhythmia that might pose a risk during exercise or training 
Congestive heart failure within 6 mo and LVEF < 45% 
Evidence or history of Cor Pulmonale 
Resting bradycardia (< 50 beats/min), frequent multifocal PVCs, complex ventricular arrhythmia, sustained SVT 
History of exercise-related syncope 
MI within 6 mo and LVEF < 45% 
Evidence of systemic disease or neoplasia expected to compromise survival during 5-yr period 
Any disease or condition that interferes with completion of initial or follow-up assessments 
Patient is currently enrolled in another clinical trial 
Patient is unable to complete 3 minutes of unloaded peddling on cycle ergometer 
Alpha-1-Antitrypsin Deficiency       
    

NCT00730301_exc_T1
Procedure
endobronchial treatment
NCT00730301_exc_T2
Condition
emphysema
NCT00730301_exc_T3
Temporal
Prior
NCT00730301_exc_T4
Condition
Pleural disease
NCT00730301_exc_T5
Condition
interstitial disease
NCT00730301_exc_T6
Procedure
surgery
NCT00730301_exc_T7
Scope
Pleural or interstitial disease
NCT00730301_exc_T8
Negation
precludes
NCT00730301_exc_T9
Qualifier
precludes surgery
NCT00730301_exc_T10
Procedure
lung transplant
NCT00730301_exc_T11
Temporal
Prior
NCT00730301_exc_T12
Procedure
LVRS
NCT00730301_exc_T13
Procedure
median sternotomy
NCT00730301_exc_T14
Procedure
bullectomy
NCT00730301_exc_T15
Procedure
lobectomy
NCT00730301_exc_T16
Scope
lung transplant, LVRS, median sternotomy, bullectomy or lobectomy.
NCT00730301_exc_T17
Condition
bronchiectasis
NCT00730301_exc_T18
Qualifier
Clinically significant
NCT00730301_exc_T19
Procedure
surgery
NCT00730301_exc_T20
Condition
Pulmonary nodule
NCT00730301_exc_T21
Condition
respiratory infections
NCT00730301_exc_T22
Multiplier
recurrent
NCT00730301_exc_T23
Observation
History
NCT00730301_exc_T24
Multiplier
> 3 in the last year
NCT00730301_exc_T25
Procedure
hospitalization
NCT00730301_exc_T26
Scope
> 3 hospitalization in the last year
NCT00730301_exc_T27
Qualifier
Clinically significant
NCT00730301_exc_T28
Multiplier
> 4 Tablespoons per day
NCT00730301_exc_T29
Observation
sputum production
NCT00730301_exc_T30
Condition
Fever
NCT00730301_exc_T31
Measurement
white cell count
NCT00730301_exc_T32
Value
elevated
NCT00730301_exc_T33
Condition
active infection
NCT00730301_exc_T34
Mood
evidence
NCT00730301_exc_T35
Condition
Dysrhythmia
NCT00730301_exc_T36
Condition
pose a risk
NCT00730301_exc_T37
Temporal
during exercise
NCT00730301_exc_T38
Reference_point
exercise
NCT00730301_exc_T39
Temporal
during training
NCT00730301_exc_T40
Reference_point
training
NCT00730301_exc_T41
Scope
during exercise or training
NCT00730301_exc_T42
Condition
Congestive heart failure
NCT00730301_exc_T43
Temporal
within 6 mo
NCT00730301_exc_T44
Measurement
LVEF
NCT00730301_exc_T45
Value
< 45%
NCT00730301_exc_T46
Condition
Cor Pulmonale
NCT00730301_exc_T47
Mood
Evidence
NCT00730301_exc_T48
Observation
history
NCT00730301_exc_T49
Scope
Evidence or history
NCT00730301_exc_T50
Condition
Resting bradycardia
NCT00730301_exc_T51
Value
< 50 beats/min
NCT00730301_exc_T52
Condition
multifocal PVCs
NCT00730301_exc_T53
Multiplier
frequent
NCT00730301_exc_T54
Condition
complex ventricular arrhythmia
NCT00730301_exc_T55
Condition
sustained SVT
NCT00730301_exc_T56
Condition
syncope
NCT00730301_exc_T57
Qualifier
exercise-related
NCT00730301_exc_T58
Observation
History
NCT00730301_exc_T59
Condition
MI
NCT00730301_exc_T60
Temporal
within 6 mo
NCT00730301_exc_T61
Measurement
LVEF
NCT00730301_exc_T62
Value
< 45%
NCT00730301_exc_T67
Condition
Alpha-1-Antitrypsin Deficiency
NCT00730301_exc_T63
Condition
systemic disease
NCT00730301_exc_T68
Condition
neoplasia
NCT00730301_exc_T69
Qualifier
expected to compromise survival
NCT00730301_exc_T70
Scope
systemic disease or neoplasia
NCT00730301_exc_T71
Temporal
during 5-yr period
NCT00730301_exc_T65
Observation
enrolled in another clinical trial
NCT00730301_exc_T66
Observation
unable to complete
NCT00730301_exc_T72
Qualifier
3 minutes of unloaded peddling on cycle ergometer
NCT00730301_exc_T64
Condition
disease
NCT00730301_exc_T73
Condition
condition
NCT00730301_exc_T74
Qualifier
interferes with completion of initial or follow-up assessments
NCT00730301_exc_T75
Scope
disease or condition
NCT00730301_exc_T76
Temporal
currently