Hemodynamically unstable in need of acute treatment 
Most recent hCG > 5000 mIU/mL 
Patient obtaining care in relation to a recently completed pregnancy (delivery, spontaneous or elective abortion) 
Diagnosis of gestational trophoblastic disease 
Subject unwilling or unable to comply with study procedures 
Known hypersensitivity to MTX 
Presence of clinical contraindications for treatment with MTX 
Prior medical or surgical management of this gestation 
Subject unwilling to accept a blood transfusion       
    

NCT02152696_exc_T1
Condition
Hemodynamically unstable
NCT02152696_exc_T2
Measurement
hCG
NCT02152696_exc_T3
Temporal
Most recent
NCT02152696_exc_T4
Value
> 5000 mIU/mL
NCT02152696_exc_T6
Condition
gestational trophoblastic disease
NCT02152696_exc_T8
Condition
hypersensitivity to MTX
NCT02152696_exc_T9
Drug
MTX
NCT02152696_exc_T11
Procedure
medical management
NCT02152696_exc_T12
Procedure
surgical management
NCT02152696_exc_T13
Condition
gestation