HIV-1 infected males or females 
over 18 years of age 
signed informed consent 
currently receiving a stable antiretroviral regimen comprising of: 
two or more licensed NRTIs 
one licensed NNRTI or boosted protease inhibitor 
no previous protease inhibitor resistance documented on HIV-1 genotypic resistance testing 
failure of current antiretroviral regimen due to: 
toxicity, intolerance or virological failure if receiving an NNRTI containing regimen at screening 
toxicity or intolerance if receiving a boosted-protease inhibitor regimen at screening (with plasma HIV RNA < 400 copies/mL at screening) 
willing to modify antiretroviral therapy, in accordance with the randomisation assignment 
no previous exposure to etravirine 
subjects in good health upon medical history, physical exam, and laboratory testing in the opinion of the investigator 
have no serologic evidence of active HBV infection evidenced by negative hepatitis B surface antigen 
female subjects who are heterosexually active and of childbearing potential (i.e., not surgically sterile or at least two years post menopausal) must practice contraception as follows from screening through completion of the study: 
barrier contraceptives (condom, diaphragm with spermicide) 
IUD or Depo PLUS a barrier contraceptive 
female subjects of childbearing potential must have a negative pregnancy test. 

NCT01118871_inc_T1
Condition
HIV-1 infected
NCT01118871_inc_T2
Person
males
NCT01118871_inc_T3
Person
females
NCT01118871_inc_T4
Value
over 18 years
NCT01118871_inc_T5
Person
age
NCT01118871_inc_T7
Procedure
antiretroviral regimen
NCT01118871_inc_T8
Multiplier
two or more
NCT01118871_inc_T9
Drug
NRTI
NCT01118871_inc_T10
Qualifier
licensed
NCT01118871_inc_T11
Multiplier
one
NCT01118871_inc_T12
Qualifier
licensed
NCT01118871_inc_T13
Drug
NNRTI
NCT01118871_inc_T14
Drug
boosted protease inhibitor
NCT01118871_inc_T15
Scope
NNRTI or boosted protease inhibitor
NCT01118871_inc_T16
Drug
protease inhibitor
NCT01118871_inc_T17
Condition
protease inhibitor resistance
NCT01118871_inc_T18
Procedure
HIV-1 genotypic resistance testing
NCT01118871_inc_T19
Condition
HIV-1
NCT01118871_inc_T20
Condition
HIV-1 genotypic resistance
NCT01118871_inc_T21
Procedure
antiretroviral regimen
NCT01118871_inc_T22
Condition
failure of current antiretroviral regimen
NCT01118871_inc_T23
Temporal
current
NCT01118871_inc_T24
Condition
toxicity
NCT01118871_inc_T25
Condition
intolerance
NCT01118871_inc_T26
Condition
virological failure
NCT01118871_inc_T27
Drug
NNRTI
NCT01118871_inc_T28
Procedure
NNRTI containing regimen
NCT01118871_inc_T29
Temporal
at screening
NCT01118871_inc_T30
Scope
NNRTI containing regimen at screening
NCT01118871_inc_T31
Scope
toxicity, intolerance or virological failure
NCT01118871_inc_T32
Condition
toxicity
NCT01118871_inc_T33
Condition
intolerance
NCT01118871_inc_T34
Procedure
boosted-protease inhibitor regimen
NCT01118871_inc_T35
Drug
protease inhibitor
NCT01118871_inc_T36
Temporal
at screening
NCT01118871_inc_T37
Measurement
plasma HIV RNA
NCT01118871_inc_T38
Value
< 400 copies/mL
NCT01118871_inc_T39
Temporal
at screening
NCT01118871_inc_T40
Scope
boosted-protease inhibitor regimen at screening (with plasma HIV RNA < 400 copies/mL at screening)
NCT01118871_inc_T41
Scope
toxicity or intolerance
NCT01118871_inc_T42
Procedure
antiretroviral therapy
NCT01118871_inc_T43
Observation
willing
NCT01118871_inc_T44
Drug
etravirine
NCT01118871_inc_T45
Negation
no
NCT01118871_inc_T46
Temporal
previous
NCT01118871_inc_T47
Condition
good health
NCT01118871_inc_T48
Observation
medical history
NCT01118871_inc_T49
Procedure
physical exam
NCT01118871_inc_T50
Procedure
laboratory testing
NCT01118871_inc_T51
Scope
medical history, physical exam, and laboratory testing
NCT01118871_inc_T52
Condition
serologic evidence of active HBV infection
NCT01118871_inc_T53
Condition
HBV infection
NCT01118871_inc_T54
Measurement
hepatitis B surface antigen
NCT01118871_inc_T55
Value
negative
NCT01118871_inc_T56
Person
female
NCT01118871_inc_T57
Condition
heterosexually active
NCT01118871_inc_T58
Condition
childbearing potential
NCT01118871_inc_T59
Condition
surgically sterile
NCT01118871_inc_T60
Procedure
surgically
NCT01118871_inc_T61
Negation
not
NCT01118871_inc_T62
Temporal
at least two years
NCT01118871_inc_T63
Condition
post menopausal
NCT01118871_inc_T64
Scope
not surgically sterile or at least two years post menopausal
NCT01118871_inc_T65
Procedure
contraception
NCT01118871_inc_T68
Device
barrier contraceptives
NCT01118871_inc_T69
Device
condom
NCT01118871_inc_T70
Device
diaphragm
NCT01118871_inc_T71
Qualifier
with spermicide
NCT01118871_inc_T72
Scope
condom, diaphragm with spermicide
NCT01118871_inc_T73
Device
IUD
NCT01118871_inc_T74
Device
Depo
NCT01118871_inc_T75
Device
barrier contraceptive
NCT01118871_inc_T76
Measurement
pregnancy test
NCT01118871_inc_T77
Value
negative
NCT01118871_inc_T78
Condition
childbearing potential
NCT01118871_inc_T79
Person
female
NCT01118871_inc_T80
Scope
female subjects of childbearing potential