1. Patient age ≥ 12 years 
2. Presence of P. knowlesi malaria, confirmed by positive blood smear with asexual forms of P. knowlesi. 
3. Temperature >38C on admission or fever during the preceding 48 hours 
4. Enrolled within 18 hours of commencing antimalarial treatment 
5. Written informed consent from patient or attending relative able to and willing to give informed consent. Consent form and information sheets will be translated into Malay and copies provided to the patient. 

NCT03056391_inc_T6
Person
age
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Value
≥ 12 years
NCT03056391_inc_T8
Condition
P. knowlesi malaria
NCT03056391_inc_T9
Measurement
blood smear
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Value
positive
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Qualifier
with asexual forms of P. knowlesi
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Measurement
Temperature
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Value
>38C
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Temporal
within 18 hours
NCT03056391_inc_T15
Observation
Enrolled
NCT03056391_inc_T16
Reference_point
commencing antimalarial treatment
NCT03056391_inc_T17
Procedure
antimalarial treatment