Paediatric subjects aged =28 days (= 1 month) to <18 years, requiring non-emergent open hepatic, abdominal, retroperitoneal, pelvic or thoracic (non-cardiac) surgical procedures. i) The first 36 subjects to be enrolled will be subjects aged =1 years to <18 years. ii) The next 4 subjects to be enrolled will be subjects aged =28 days to <1 year.
The subject's parent/legal guardian must be willing to give permission for the subject to participate in the trial, and provide written informed consent for the subject. In addition, assent must be obtained from paediatric subjects who possess the intellectual and emotional ability to comprehend the concepts involved in the trial. If the paediatric subject is not able to provide assent (due to age, maturity and/or inability to intellectually and/or emotionally comprehend the trial), the parent/legal guardian's written Informed Consent for the subject will be acceptable for the subject to be included in the study.
Presence of an appropriate mild or moderate bleeding soft tissue or hepatic parenchyma Target Bleeding Site (TBS) identified intra-operatively by the surgeon;
Ability to firmly press trial treatment at TBS until 4 minutes after randomisation

NCT02227992_inc_T1
Person
aged
NCT02227992_inc_T2
Value
=28 days (= 1 month) to <18 years
NCT02227992_inc_T3
Procedure
surgical procedures
NCT02227992_inc_T4
Qualifier
thoracic
NCT02227992_inc_T5
Qualifier
pelvic
NCT02227992_inc_T6
Qualifier
retroperitoneal
NCT02227992_inc_T7
Qualifier
abdominal
NCT02227992_inc_T8
Qualifier
hepatic
NCT02227992_inc_T9
Qualifier
open
NCT02227992_inc_T10
Qualifier
non-emergent
NCT02227992_inc_T11
Qualifier
non-cardiac
NCT02227992_inc_T12
Scope
hepatic, abdominal, retroperitoneal, pelvic or thoracic (non-cardiac)