Received any vaccine within a month prior to study vaccine
Positive serum antibody against Hep B surface antigen and/or core Hep B core antigen
HIV positive
For HCV-negative, healthy volunteers: History of HCV infection or positive HCV antibody test
Participation in another clinical study of an investigational product currently or within the past 90 days, or expected participation during this study
In the opinion of the investigator, the volunteer is unlikely to comply with the study protocol
Any clinically significant abnormality or medical history or physical examination including history of immunodeficiency or autoimmune disease (in addition to HCV infection, for HCV group)
Currently taking systemic steroids or other immunomodulatory medications including anticancer medications and antiviral medications
Any clinically significant acute or chronic medical condition requiring care by a primary care provider (e.g., diabetes, coronary artery disease, rheumatologic illness, malignancy, substance abuse) that, in the opinion of the investigator, would preclude participation
Unable to continue participation for 156 weeks
History of previous Hepatitis B vaccination(s)
Male or female < 18 and > 62 years of age
Is pregnant or lactating
History of Hepatitis B infection
Clinical, laboratory, or biopsy evidence of cirrhosis

NCT02429583_exc_T1
Procedure
vaccine
NCT02429583_exc_T2
Temporal
within a month prior to study vaccine
NCT02429583_exc_T3
Reference_point
study vaccine
NCT02429583_exc_T4
Measurement
serum antibody
NCT02429583_exc_T5
Qualifier
Hep B surface antige
NCT02429583_exc_T6
Qualifier
core Hep B core antigen
NCT02429583_exc_T7
Scope
Hep B surface antigen and/or core Hep B core antigen
NCT02429583_exc_T8
Value
Positive
NCT02429583_exc_T9
Measurement
HIV
NCT02429583_exc_T10
Value
positive
NCT02429583_exc_T11
Measurement
HCV
NCT02429583_exc_T12
Value
negative
NCT02429583_exc_T13
Observation
History of HCV infection
NCT02429583_exc_T16
Condition
immunodeficiency
NCT02429583_exc_T17
Condition
autoimmune disease
NCT02429583_exc_T18
Negation
in addition to
NCT02429583_exc_T19
Condition
HCV infection
NCT02429583_exc_T20
Drug
systemic steroids
NCT02429583_exc_T21
Procedure
immunomodulatory medications
NCT02429583_exc_T22
Procedure
anticancer medications
NCT02429583_exc_T23
Procedure
antiviral medications
NCT02429583_exc_T24
Scope
anticancer medications and antiviral medications
NCT02429583_exc_T25
Condition
diabetes
NCT02429583_exc_T26
Condition
coronary artery disease
NCT02429583_exc_T27
Condition
rheumatologic illness
NCT02429583_exc_T28
Condition
malignancy
NCT02429583_exc_T29
Condition
substance abuse
NCT02429583_exc_T31
Procedure
Hepatitis B vaccination
NCT02429583_exc_T32
Person
Male
NCT02429583_exc_T33
Person
female
NCT02429583_exc_T34
Value
< 18 and > 62 years
NCT02429583_exc_T35
Person
age
NCT02429583_exc_T37
Condition
Hepatitis B infection
NCT02429583_exc_T38
Condition
cirrhosis