GCS less than 15
Preoperative Heart Rate less than 50 beat/min
No Beta-Blockers
Pregnant patients
Take any Alpha-Methyldopa, Clonodine, Other Alpha-2 Adrenergic Agonist
Hemodynamic unstable
Systolic BP more than 160mmHg
CAD
Renal insuffuciency
Allergy in dexmedethomidine and opioid
BMI more than 30
Denied consent

NCT03132259_exc_T1
Measurement
GCS
NCT03132259_exc_T2
Value
less than 15
NCT03132259_exc_T3
Measurement
Preoperative Heart Rate
NCT03132259_exc_T4
Value
less than 50 beat/min
NCT03132259_exc_T5
Negation
No
NCT03132259_exc_T6
Drug
Beta-Blockers
NCT03132259_exc_T7
Condition
Pregnant
NCT03132259_exc_T8
Drug
Alpha-Methyldopa
NCT03132259_exc_T9
Drug
Clonodine
NCT03132259_exc_T10
Qualifier
Other
NCT03132259_exc_T11
Drug
Alpha-2 Adrenergic Agonist
NCT03132259_exc_T12
Condition
Hemodynamic unstable
NCT03132259_exc_T13
Measurement
Systolic BP
NCT03132259_exc_T14
Value
more than 160mmHg
NCT03132259_exc_T15
Condition
CAD
NCT03132259_exc_T16
Condition
Renal insuffuciency
NCT03132259_exc_T17
Condition
Allergy
NCT03132259_exc_T18
Drug
dexmedethomidine
NCT03132259_exc_T19
Drug
opioid
NCT03132259_exc_T20
Scope
dexmedethomidine and opioid
NCT03132259_exc_T21
Measurement
BMI
NCT03132259_exc_T22
Value
more than 30