Clinically significant cardiac disease (New York Heart Association Class III/IV),or severe debilitating puhnonary disease. 
Uncontrolled serious active infection. 
Anticipated survival of less than 3 months. 
Active CNS or epiduraltumor 
Inability or unwillingness to comply with the treatment protocol, follow-up, or research tests.       
    

NCT00586898_exc_T1
Condition
cardiac disease
NCT00586898_exc_T2
Measurement
New York Heart Association
NCT00586898_exc_T3
Value
Class III/IV
NCT00586898_exc_T4
Qualifier
significant
NCT00586898_exc_T5
Condition
debilitating puhnonary disease
NCT00586898_exc_T6
Qualifier
severe
NCT00586898_exc_T7
Condition
infection
NCT00586898_exc_T8
Qualifier
Uncontrolled serious
NCT00586898_exc_T9
Observation
Anticipated survival
NCT00586898_exc_T10
Value
less than 3 months
NCT00586898_exc_T11
Condition
CNS tumor
NCT00586898_exc_T12
Condition
epiduraltumor
NCT00586898_exc_T13
Condition
Inability
NCT00586898_exc_T14
Observation
unwillingness
NCT00586898_exc_T16
Procedure
follow-up
NCT00586898_exc_T18
Scope
comply with the treatment protocol, follow-up, or research tests
NCT00586898_exc_T19
Scope
Inability or unwillingness