Subjects aged 12-65. 
Confirmed idiopathic pulmonary hypertension, connective tissue disease associated pulmonary hypertension, congenital heart disease(with Eisenmenger syndrome) associated pulmonary hypertension. 
Baseline 6-minutes walking distance 150m-550m. 
WHO pulmonary hypertension function II-III with non-responder to calcium channel blockers. 
Documented written informed consent. 

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Person
aged
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Value
12-65
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Condition
idiopathic pulmonary hypertension
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Qualifier
connective tissue disease associated
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Condition
pulmonary hypertension
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Qualifier
congenital heart disease
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Condition
Eisenmenger syndrome
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Condition
pulmonary hypertension
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Measurement
6-minutes walking distance
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Value
150m-550m
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Temporal
Baseline
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Measurement
WHO pulmonary hypertension function
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Value
II-III
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Condition
non-responder to calcium channel blockers
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Drug
calcium channel blockers
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Observation
written informed consent