Patients with head trauma or Neurosurgical intervention
Patients <65 years of age
Patients with an expected life expectancy <48 hours
Blind patients
Patients with a seizure history
Patients with uncontrolled hypertension
Patients with a supratheraputic (>3.0) INR
Patients on strong CYP1A2 inhibitors: ciprofloxacin, fluvoxamine, methoxsalen, ofloxacin, primaquine
Patients who do not speak English or Spanish

NCT03013790_exc_T1
Condition
head trauma
NCT03013790_exc_T2
Procedure
Neurosurgical intervention
NCT03013790_exc_T3
Value
<65 years
NCT03013790_exc_T4
Person
age
NCT03013790_exc_T5
Observation
expected life expectancy
NCT03013790_exc_T6
Value
<48 hours
NCT03013790_exc_T7
Condition
Blind
NCT03013790_exc_T8
Condition
seizure
NCT03013790_exc_T9
Observation
history
NCT03013790_exc_T10
Condition
uncontrolled hypertension
NCT03013790_exc_T11
Value
supratheraputic
NCT03013790_exc_T12
Value
>3.0
NCT03013790_exc_T13
Measurement
INR
NCT03013790_exc_T14
Drug
ciprofloxacin
NCT03013790_exc_T15
Drug
fluvoxamine
NCT03013790_exc_T16
Drug
methoxsalen
NCT03013790_exc_T17
Drug
ofloxacin
NCT03013790_exc_T18
Drug
primaquine
NCT03013790_exc_T19
Drug
strong CYP1A2 inhibitors
NCT03013790_exc_T20
Scope
ciprofloxacin, fluvoxamine, methoxsalen, ofloxacin, primaquine
NCT03013790_exc_T21
Negation
not
NCT03013790_exc_T22
Observation
speak English
NCT03013790_exc_T23
Observation
glish
NCT03013790_exc_T24
Scope
speak English or Spanish