Re-transplant;
Patients with any panel reactive antibody (PRA) equal to or above 50%, class I or class II;
Acute rejection episode in the last 30 days, or episode > 2A in the Banff criteria;
GFR (MDRD) < 40 ml/min;
Proteinuria > 0,5 g/l;
Hemoglobin < 10 g/l and/or leucocytes < 4000 cels/mm3 and/or platelets < 150.000 cels/mm3;
Triglycerides > 500 mg/dl with or without use of fibrate;
Cholesterol total > 300 mg/dl with or without use of statin;
Hepatic abnormalities;
Significant periphery edema;
Pulmonary abnormalities or breast x-ray abnormalities;
Hyper sensibility to sirolimus formula;

NCT02671318_exc_T1
Procedure
Re-transplant
NCT02671318_exc_T2
Measurement
panel reactive antibody
NCT02671318_exc_T3
Measurement
PRA
NCT02671318_exc_T4
Value
equal to or above 50%
NCT02671318_exc_T5
Value
class I
NCT02671318_exc_T6
Value
class II
NCT02671318_exc_T7
Scope
equal to or above 50%, class I or class II
NCT02671318_exc_T8
Condition
Acute rejection episode
NCT02671318_exc_T9
Temporal
last 30 days
NCT02671318_exc_T10
Measurement
Banff criteria
NCT02671318_exc_T11
Value
> 2A
NCT02671318_exc_T12
Measurement
GFR
NCT02671318_exc_T14
Value
< 40 ml/min
NCT02671318_exc_T13
Condition
Proteinuria
NCT02671318_exc_T15
Multiplier
> 0,5 g/l
NCT02671318_exc_T16
Measurement
Hemoglobin
NCT02671318_exc_T17
Value
< 10 g/l
NCT02671318_exc_T18
Measurement
leucocytes
NCT02671318_exc_T19
Value
< 4000 cels/mm3
NCT02671318_exc_T20
Measurement
platelets
NCT02671318_exc_T21
Value
< 150.000 cels/mm3
NCT02671318_exc_T22
Measurement
Triglycerides
NCT02671318_exc_T23
Value
> 500 mg/dl
NCT02671318_exc_T24
Drug
fibrate
NCT02671318_exc_T25
Measurement
Cholesterol total
NCT02671318_exc_T26
Value
> 300 mg/dl
NCT02671318_exc_T27
Drug
statin
NCT02671318_exc_T28
Condition
Hepatic abnormalities
NCT02671318_exc_T29
Condition
periphery edema
NCT02671318_exc_T30
Qualifier
Significant
NCT02671318_exc_T31
Condition
Pulmonary abnormalities
NCT02671318_exc_T32
Procedure
breast x-ray
NCT02671318_exc_T33
Value
abnormalities
NCT02671318_exc_T34
Condition
Hyper sensibility
NCT02671318_exc_T35
Drug
sirolimus