HCV, HIV, or HDV coinfection.
HCC or other malignancy within 3 years.
Decompensated liver cirrhosis (CTP score = 7).
Uremia patients under hemodialysis or continuous ambulatory peritoneal dialysis or patients with Ccr < 50 mL/min
Pregnant or breastfeeding women.
Women of child-bearing potential (WOCBP) who are unwilling or unable to use an acceptable method of contraception to avoid pregnancy throughout the study and for up to 4 weeks after the last dose of study drug.

NCT01907230_exc_T1
Condition
HCV coinfection
NCT01907230_exc_T2
Condition
coinfection HIV
NCT01907230_exc_T3
Condition
HDV coinfection
NCT01907230_exc_T4
Condition
HCC
NCT01907230_exc_T5
Condition
malignancy
NCT01907230_exc_T6
Temporal
within 3 years
NCT01907230_exc_T7
Scope
HCC or other malignancy
NCT01907230_exc_T8
Condition
Decompensated liver cirrhosis
NCT01907230_exc_T9
Measurement
CTP score
NCT01907230_exc_T10
Value
= 7
NCT01907230_exc_T11
Condition
Uremia
NCT01907230_exc_T12
Procedure
hemodialysis
NCT01907230_exc_T13
Condition
continuous ambulatory peritoneal dialysis
NCT01907230_exc_T14
Measurement
Ccr
NCT01907230_exc_T15
Value
< 50 mL/min
NCT01907230_exc_T16
Scope
hemodialysis or continuous ambulatory peritoneal dialysis
NCT01907230_exc_T17
Scope
hemodialysis or continuous ambulatory peritoneal dialysis or patients with Ccr < 50 mL/min