Presence of systemic diseases;
Presence of local inflammation and/or infection;
Any history of allergic reaction to local anesthetics, gastrointestinal bleeding or ulceration;
Cardiovascular, kidney or hepatic diseases;
Patients who are making use of antidepressants, diuretics or anticoagulants;
Asthma and allergy to aspirin, ibuprofen or any other nonsteroidal antiinflammatory drug;
Regular use of any nonsteroidal antiinflammatory drug,
Pregnancy or breast feeding.

NCT03169127_exc_T1
Condition
systemic diseases
NCT03169127_exc_T2
Condition
local inflammation
NCT03169127_exc_T3
Condition
ocal nfection;
NCT03169127_exc_T4
Observation
history
NCT03169127_exc_T5
Condition
allergic reaction
NCT03169127_exc_T6
Drug
local anesthetics
NCT03169127_exc_T7
Condition
gastrointestinal bleeding
NCT03169127_exc_T8
Condition
strointestinal b ceration;
NCT03169127_exc_T9
Scope
allergic reaction to local anesthetics, gastrointestinal bleeding or ulceration
NCT03169127_exc_T10
Condition
diovascular, k eases;
P
NCT03169127_exc_T11
Condition
ney or eases;
P
NCT03169127_exc_T12
Condition
hepatic diseases
NCT03169127_exc_T13
Drug
antidepressants
NCT03169127_exc_T14
Drug
diuretics
NCT03169127_exc_T15
Drug
anticoagulants
NCT03169127_exc_T16
Condition
Asthma
NCT03169127_exc_T17
Condition
allergy
NCT03169127_exc_T18
Drug
aspirin
NCT03169127_exc_T19
Drug
ibuprofen
NCT03169127_exc_T20
Drug
nonsteroidal antiinflammatory drug
NCT03169127_exc_T21
Qualifier
any other
NCT03169127_exc_T22
Scope
aspirin, ibuprofen or any other nonsteroidal antiinflammatory drug
NCT03169127_exc_T23
Multiplier
Regular use
NCT03169127_exc_T24
Condition
nonsteroidal antiinflammatory drug
NCT03169127_exc_T25
Condition
Pregnancy
NCT03169127_exc_T26
Observation
breast feeding