Must be an outpatient with a primary DSM-IV Obsessive-Compulsive Disorder. Patients must have a score of greater than 20 on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS; Goodman et al., 1989b).
Diagnosis of comorbid DSM-IV major depressive episode will be allowed in the study provided that the diagnosis is secondary to OCD, they have a baseline Montgomery Depression Rating Scale (MADRS) score of less than or equal to 19, and the onset of OCD predates the onset of the current episode of depression by five or more years.
The ability to comprehend and comply with protocol requirements.
Written consent must be provided prior to study entry.
All women of childbearing potential (WOCBP) must be practicing a medically acceptable method of birth control
All female subjects of childbearing potential (WOCBP), including those who are practicing a medically acceptable method of birth control, must have a negative serum pregnancy test within 72 hours prior to the start of study medication.

NCT00994786_inc_T1
Condition
Obsessive-Compulsive Disorder
NCT00994786_inc_T2
Qualifier
primary
NCT00994786_inc_T3
Qualifier
DSM-IV
NCT00994786_inc_T4
Scope
primary DSM-IV
NCT00994786_inc_T5
Visit
outpatient
NCT00994786_inc_T6
Measurement
Yale-Brown Obsessive Compulsive Scale
NCT00994786_inc_T7
Value
score of greater than 20
NCT00994786_inc_T8
Measurement
Y-BOCS
NCT00994786_inc_T9
Condition
major depressive episode
NCT00994786_inc_T10
Qualifier
DSM-IV
NCT00994786_inc_T11
Qualifier
comorbid
NCT00994786_inc_T12
Scope
comorbid DSM-IV
NCT00994786_inc_T13
Condition
OCD
NCT00994786_inc_T14
Measurement
Montgomery Depression Rating Scale
NCT00994786_inc_T15
Qualifier
baseline
NCT00994786_inc_T16
Measurement
MADRS
NCT00994786_inc_T17
Value
score of less than or equal to 19
NCT00994786_inc_T18
Condition
onset of OCD
NCT00994786_inc_T19
Temporal
predates the onset of the current episode of depression by five or more years
NCT00994786_inc_T20
Reference_point
onset of the current episode of depression
NCT00994786_inc_T23
Person
women
NCT00994786_inc_T25
Condition
childbearing potential
NCT00994786_inc_T26
Condition
WOCBP
NCT00994786_inc_T27
Scope
women of childbearing potential
NCT00994786_inc_T28
Qualifier
medically acceptable
NCT00994786_inc_T29
Procedure
birth control