Hemochromatosis, iron overload, defined as TSAT > 45%
Known hypersensitivity to Ferinject®.
Known active infection, CRP>20 mg/L, clinically significant bleeding, active malignancy.
Chronic liver disease and/or screening alanine transaminase (ALT) or aspartate transaminase (AST) above three times the upper limit of the normal range.
Immunosuppressive therapy or renal dialysis (current or planned within the next 6 months).
History of erythropoietin, i. v. or oral iron therapy, and blood transfusion in previous 12 weeks and/or such therapy planned within the next 6 months.
Unstable angina pectoris as judged by the investigator, clinically significant uncorrected valvular disease or left ventricular outflow obstruction, obstructive cardiomyopathy, poorly controlled fast atrial fibrillation or flutter, poorly controlled symptomatic brady- or tachyarrhythmias.
Acute myocardial infarction or acute coronary syndrome, transient ischemic attack or stroke within the last 3 months.
Coronary-artery bypass graft, percutaneous intervention (e.g. cardiac, cerebrovascular, aortic; diagnostic catheters are allowed) or major surgery, including thoracic and cardiac surgery, within the last 3 months.
Participation in a CHF training program.
Known HIV/AIDS.
Inability to fully comprehend and/or perform study procedures in the investigator's opinion.
Vitamin B12 and/or serum folate deficiency according to the laboratory (re-screening is possible after substitution therapy).
Pregnancy or lactation.
Participation in another clinical trial within previous 30 days and/or anticipated participation in another trial during this study.
Anticoagulation

NCT01978028_exc_T1
Condition
Hemochromatosis
NCT01978028_exc_T2
Condition
iron overload
NCT01978028_exc_T3
Measurement
TSAT
NCT01978028_exc_T4
Value
> 45%
NCT01978028_exc_T5
Condition
hypersensitivity
NCT01978028_exc_T6
Drug
Ferinject®
NCT01978028_exc_T7
Measurement
CRP
NCT01978028_exc_T8
Value
>20 mg/L
NCT01978028_exc_T9
Condition
active infection
NCT01978028_exc_T10
Qualifier
clinically significant
NCT01978028_exc_T11
Condition
bleeding
NCT01978028_exc_T12
Qualifier
active
NCT01978028_exc_T13
Condition
malignancy
NCT01978028_exc_T14
Condition
Chronic liver disease
NCT01978028_exc_T15
Measurement
alanine transaminase (ALT)
NCT01978028_exc_T16
Measurement
aspartate transaminase (AST)
NCT01978028_exc_T17
Value
above three times the upper limit of the normal range
NCT01978028_exc_T18
Scope
alanine transaminase (ALT) or aspartate transaminase (AST)
NCT01978028_exc_T19
Procedure
Immunosuppressive therapy
NCT01978028_exc_T20
Condition
renal dialysis
NCT01978028_exc_T21
Mood
current
NCT01978028_exc_T22
Mood
planned
NCT01978028_exc_T23
Temporal
within the next 6 months
NCT01978028_exc_T24
Reference_point
the next 6 months
NCT01978028_exc_T25
Scope
current or planned
NCT01978028_exc_T26
Scope
Immunosuppressive therapy or renal dialysis
NCT01978028_exc_T27
Drug
erythropoietin
NCT01978028_exc_T28
Procedure
oral iron therapy
NCT01978028_exc_T29
Procedure
blood transfusion
NCT01978028_exc_T30
Temporal
in previous 12 weeks
NCT01978028_exc_T31
Mood
planned
NCT01978028_exc_T32
Temporal
within the next 6 months
NCT01978028_exc_T33
Reference_point
the next 6 months
NCT01978028_exc_T34
Procedure
 or  therapy, and
NCT01978028_exc_T35
Scope
erythropoietin, i. v. or oral iron therapy, and blood transfusion
NCT01978028_exc_T36
Scope
in previous 12 weeks and/or such therapy planned within the next 6 months
NCT01978028_exc_T37
Condition
Unstable angina pectoris
NCT01978028_exc_T38
Qualifier
clinically significant
NCT01978028_exc_T39
Condition
valvular disease
NCT01978028_exc_T40
Condition
left ventricular outflow obstruction
NCT01978028_exc_T41
Condition
obstructive cardiomyopathy
NCT01978028_exc_T42
Qualifier
poorly controlled
NCT01978028_exc_T43
Condition
fast atrial fibrillation
NCT01978028_exc_T44
Condition
trial fibri r, poor
NCT01978028_exc_T45
Qualifier
poorly controlled
NCT01978028_exc_T46
Qualifier
symptomatic
NCT01978028_exc_T47
Condition
tachyarrhythmias
NCT01978028_exc_T48
Condition
brady-
NCT01978028_exc_T49
Scope
brady- or tachyarrhythmias
NCT01978028_exc_T50
Scope
fast atrial fibrillation or flutter
NCT01978028_exc_T51
Condition
Acute myocardial infarction
NCT01978028_exc_T52
Condition
acute coronary syndrome
NCT01978028_exc_T53
Condition
transient ischemic attack
NCT01978028_exc_T54
Condition
stroke
NCT01978028_exc_T55
Temporal
within the last 3 months
NCT01978028_exc_T56
Reference_point
the last 3 months
NCT01978028_exc_T57
Scope
Acute myocardial infarction or acute coronary syndrome, transient ischemic attack or stroke
NCT01978028_exc_T58
Procedure
Coronary-artery bypass graft
NCT01978028_exc_T59
Procedure
percutaneous intervention
NCT01978028_exc_T60
Procedure
major surgery
NCT01978028_exc_T61
Procedure
cardiac surgery
NCT01978028_exc_T62
Procedure
 and ca  withi
NCT01978028_exc_T63
Temporal
within the last 3 months
NCT01978028_exc_T64
Reference_point
the last 3 months
NCT01978028_exc_T65
Scope
thoracic and cardiac surgery
NCT01978028_exc_T67
Condition
Known HIV
NCT01978028_exc_T68
Condition
AIDS
NCT01978028_exc_T70
Condition
and/or seru ccording t
NCT01978028_exc_T71
Condition
serum folate deficiency
NCT01978028_exc_T72
Condition
lactation
NCT01978028_exc_T73
Condition
Pregnancy
NCT01978028_exc_T74
Procedure
Anticoagulation