Columbia-Suicide Severity Rating Scale (C-SSRS) for suicidal ideation and behavior in past year.
Hypersensitivity to morphine, naltrexone.
A life expectancy (assessed by investigator) of less than 6 months or is no longer capable of taking medication orally.
Undergone surgery within 3 days prior to the first day of dosing.

NCT02101554_exc_T1
Measurement
Columbia-Suicide Severity Rating Scale
NCT02101554_exc_T2
Measurement
C-SSRS
NCT02101554_exc_T3
Condition
suicidal ideation
NCT02101554_exc_T4
Condition
suicidal behavior
NCT02101554_exc_T5
Temporal
in past year
NCT02101554_exc_T6
Scope
suicidal ideation and behavior
NCT02101554_exc_T7
Condition
Hypersensitivity
NCT02101554_exc_T8
Drug
morphine
NCT02101554_exc_T9
Drug
naltrexone
NCT02101554_exc_T10
Scope
morphine, naltrexone
NCT02101554_exc_T11
Observation
life expectancy
NCT02101554_exc_T12
Value
less than 6 months
NCT02101554_exc_T14
Procedure
surgery
NCT02101554_exc_T15
Temporal
within 3 days prior to the first day of dosing
NCT02101554_exc_T16
Reference_point
first day of dosing