Moderate to severe rheumatoid arthritis
Taking methotrexate without adequate control of symptoms
Have at least one cardiovascular risk factor (eg, current smoker, high blood pressure, high cholesterol levels, diabetes mellitus, history of heart attack, family history of coronary heart disease, extra-articular RA disease)

NCT02092467_inc_T1
Qualifier
Moderate to severe
NCT02092467_inc_T2
Condition
rheumatoid arthritis
NCT02092467_inc_T3
Drug
methotrexate
NCT02092467_inc_T4
Negation
without
NCT02092467_inc_T5
Observation
adequate control of symptoms
NCT02092467_inc_T6
Multiplier
at least one
NCT02092467_inc_T7
Condition
cardiovascular risk factor
NCT02092467_inc_T8
Temporal
current
NCT02092467_inc_T9
Observation
smoker
NCT02092467_inc_T10
Condition
high blood pressure
NCT02092467_inc_T11
Condition
high cholesterol levels
NCT02092467_inc_T12
Condition
diabetes mellitus
NCT02092467_inc_T13
Observation
history
NCT02092467_inc_T14
Condition
heart attack
NCT02092467_inc_T15
Observation
family history
NCT02092467_inc_T16
Condition
coronary heart disease
NCT02092467_inc_T17
Qualifier
extra-articular
NCT02092467_inc_T18
Condition
RA disease
NCT02092467_inc_T19
Scope
current smoker, high blood pressure, high cholesterol levels, diabetes mellitus, history of heart attack, family history of coronary heart disease, extra-articular RA disease