Known hypersensitivity to paracetamol or mannitol (excipient with known effect)
Severe hepatocellular insufficiency (ASAT or ALAT > 5N, or bilirubin > 2N)
Pharmacological intervention (administration of corticosteroids, NSAIDs or paracetamol) or physical intervention (external cooling technique) that may influence temperature in the last 6 hours.
Pregnant or breastfeeding women
Previous participation in this study

NCT03648021_exc_T1
Condition
hypersensitivity
NCT03648021_exc_T2
Drug
paracetamol
NCT03648021_exc_T3
Drug
mannitol
NCT03648021_exc_T5
Scope
paracetamol or mannitol
NCT03648021_exc_T6
Condition
hepatocellular insufficiency
NCT03648021_exc_T7
Measurement
ASAT
NCT03648021_exc_T8
Measurement
ALAT
NCT03648021_exc_T9
Value
> 5N
NCT03648021_exc_T11
Measurement
bilirubin
NCT03648021_exc_T12
Value
> 2N
NCT03648021_exc_T10
Scope
ASAT or ALAT > 5N, or bilirubin > 2N
NCT03648021_exc_T13
Procedure
Pharmacological intervention
NCT03648021_exc_T14
Drug
Pharmacological
NCT03648021_exc_T15
Drug
corticosteroids
NCT03648021_exc_T16
Drug
NSAIDs
NCT03648021_exc_T17
Drug
paracetamol
NCT03648021_exc_T18
Scope
corticosteroids, NSAIDs or paracetamol
NCT03648021_exc_T19
Procedure
physical intervention
NCT03648021_exc_T20
Procedure
external cooling technique
NCT03648021_exc_T21
Qualifier
that may influence temperature
NCT03648021_exc_T22
Temporal
in the last 6 hours
NCT03648021_exc_T23
Scope
Pharmacological intervention (administration of corticosteroids, NSAIDs or paracetamol) or physical intervention (external cooling technique)
NCT03648021_exc_T24
Measurement
temperature
NCT03648021_exc_T25
Condition
Pregnant
NCT03648021_exc_T26
Observation
breastfeeding
NCT03648021_exc_T27
Person
women