Previous randomization in this study
Treatment with IV antibiotics in the 6 weeks prior to Visit 1
Admission to the intensive care unit for current pulmonary exacerbation in the two weeks prior to Visit 2, unless admission was due to a desensitization protocol
Pneumothorax in the two weeks prior to Visit 2
Primary diagnosis for current hospitalization is unrelated to worsening lower respiratory symptoms (e.g., pulmonary clean out, distal intestinal obstruction syndrome (DIOS), sinusitis)
Massive hemoptysis defined as > 250 cc in a 24 hour period or 100 cc/day over 4 consecutive days occurring in the two weeks prior to Visit 2
Current pulmonary exacerbation thought to be due to allergic bronchopulmonary aspergillosis (ABPA)
At Visit 1, receiving ongoing treatment with a duration of more than 2 weeks with prednisone equivalent to >10mg/day
History of solid organ transplantation
Receiving antimicrobial therapy to treat non-tuberculous mycobacterium (e.g., M. abscessus, M. avium complex) in the two weeks prior to Visit 2

NCT02781610_exc_T2
Drug
IV antibiotics
NCT02781610_exc_T3
Temporal
in the 6 weeks prior to Visit 1
NCT02781610_exc_T4
Reference_point
Visit 1
NCT02781610_exc_T5
Observation
Admission to the intensive care unit
NCT02781610_exc_T6
Visit
intensive care unit
NCT02781610_exc_T7
Condition
pulmonary exacerbation
NCT02781610_exc_T8
Temporal
in the two weeks prior to Visit 2
NCT02781610_exc_T9
Reference_point
Visit 2
NCT02781610_exc_T11
Procedure
desensitization protocol
NCT02781610_exc_T10
Negation
unless
NCT02781610_exc_T12
Condition
Pneumothorax
NCT02781610_exc_T13
Temporal
in the two weeks prior to Visit 2
NCT02781610_exc_T14
Reference_point
Visit 2
NCT02781610_exc_T15
Condition
Primary diagnosis
NCT02781610_exc_T16
Observation
current hospitalization
NCT02781610_exc_T17
Negation
unrelated
NCT02781610_exc_T18
Condition
lower respiratory symptoms
NCT02781610_exc_T19
Qualifier
worsening
NCT02781610_exc_T20
Condition
pulmonary clean out
NCT02781610_exc_T21
Condition
distal intestinal obstruction syndrome
NCT02781610_exc_T22
Condition
DIOS
NCT02781610_exc_T23
Condition
sinusitis
NCT02781610_exc_T24
Scope
(e.g., pulmonary clean out, distal intestinal obstruction syndrome (DIOS), sinusitis)
NCT02781610_exc_T25
Condition
hemoptysis
NCT02781610_exc_T26
Qualifier
Massive
NCT02781610_exc_T27
Multiplier
> 250 cc
NCT02781610_exc_T28
Temporal
in a 24 hour period
NCT02781610_exc_T29
Multiplier
100 cc/day
NCT02781610_exc_T30
Temporal
over 4 consecutive days
NCT02781610_exc_T31
Temporal
in the two weeks prior to Visit 2
NCT02781610_exc_T32
Reference_point
Visit 2
NCT02781610_exc_T33
Scope
> 250 cc in a 24 hour period or 100 cc/day over 4 consecutive days
NCT02781610_exc_T34
Condition
pulmonary exacerbation
NCT02781610_exc_T35
Condition
allergic bronchopulmonary aspergillosis
NCT02781610_exc_T36
Condition
ABPA
NCT02781610_exc_T38
Temporal
t 1, recei an 2 weeks with p
NCT02781610_exc_T37
Drug
prednisone
NCT02781610_exc_T39
Multiplier
>10mg/day
NCT02781610_exc_T40
Reference_point
Visit 1
NCT02781610_exc_T41
Condition
solid organ transplantation
NCT02781610_exc_T42
Drug
antimicrobial therapy
NCT02781610_exc_T43
Qualifier
non-tuberculous mycobacterium
NCT02781610_exc_T44
Qualifier
M. abscessus
NCT02781610_exc_T45
Qualifier
M. avium complex
NCT02781610_exc_T46
Temporal
in the two weeks prior to Visit 2
NCT02781610_exc_T47
Reference_point
Visit 2