Males and females who are at least 18 years of age at time of enrollment. 
Subject understands the investigational nature of the study and provides written, informed consent. 

NCT02322203_inc_T1
Person
Males
NCT02322203_inc_T2
Person
females
NCT02322203_inc_T3
Value
at least 18 years
NCT02322203_inc_T4
Person
age
NCT02322203_inc_T5
Temporal
at time of enrollment
NCT02322203_inc_T6
Reference_point
time of enrollment