Smoker or former smoker.
Presence of dental prostheses.
Presence of orthodontic devices.
Antibiotic treatment or routine use of oral antiseptics in the previous 3 months.
Presence of any systemic disease that could alter the production or composition of saliva.

NCT03146390_exc_T1
Condition
Smoker
NCT03146390_exc_T2
Condition
former smoker
NCT03146390_exc_T3
Device
dental prostheses
NCT03146390_exc_T4
Device
orthodontic devices
NCT03146390_exc_T5
Drug
Antibiotic
NCT03146390_exc_T6
Multiplier
routine use
NCT03146390_exc_T7
Drug
oral antiseptics
NCT03146390_exc_T8
Temporal
in the previous 3 months
NCT03146390_exc_T9
Condition
systemic disease
NCT03146390_exc_T10
Qualifier
could alter the production or composition of saliva