Atypical Parkinsonian Syndromes
Parkinson's disease with hallucinations
Parkinson's disease with impulse Control disorder (ICD)
Parkinson's disease already treated with APOMORPHINE pump or justifying the use of the pump continuously day and night
Another obvious severe disease explaining insomnia
Exclusion for monitoring difficulties (mutation, insufficient motivation, priority associated pathology in care)
Patient unwilling to accept a pump
Patient not accepting polysomnography and multiple sleep latency test
Patient with health problems or a skin disease precluding continuous subcutaneous infusion
Female parturient or nursing
Cardiac dysrhythmia precluding treatment with domperidone or apomorphine (increased QTc = 440 ms in men, QTc = 450 ms in women)
antiemetic neuroleptics
Tetrabenazine
Excessive alcohol consumption
Hypersensitivity to apomorphine or one of the excipients
Respiratory Depression
Hepatic impairment
Intellectual Disability
Dementia

NCT02940912_exc_T1
Qualifier
Atypical
NCT02940912_exc_T2
Condition
Parkinsonian Syndromes
NCT02940912_exc_T3
Condition
Parkinson's disease
NCT02940912_exc_T4
Condition
hallucinations
NCT02940912_exc_T5
Condition
Parkinson's disease
NCT02940912_exc_T6
Condition
impulse Control disorder (ICD)
NCT02940912_exc_T7
Condition
Parkinson's disease
NCT02940912_exc_T8
Drug
APOMORPHINE
NCT02940912_exc_T10
Condition
severe disease
NCT02940912_exc_T11
Condition
insomnia
NCT02940912_exc_T13
Mood
unwilling to accept
NCT02940912_exc_T14
Negation
unwilling
NCT02940912_exc_T15
Device
pump
NCT02940912_exc_T16
Procedure
polysomnography
NCT02940912_exc_T17
Mood
not accepting
NCT02940912_exc_T18
Negation
not
NCT02940912_exc_T19
Procedure
multiple sleep latency test
NCT02940912_exc_T20
Condition
health problems
NCT02940912_exc_T21
Condition
skin disease
NCT02940912_exc_T22
Negation
precluding
NCT02940912_exc_T23
Procedure
continuous subcutaneous infusion
NCT02940912_exc_T24
Scope
health problems or a skin disease
NCT02940912_exc_T25
Person
Female
NCT02940912_exc_T26
Condition
parturient
NCT02940912_exc_T27
Condition
nursing
NCT02940912_exc_T28
Condition
Cardiac dysrhythmia
NCT02940912_exc_T29
Drug
domperidone
NCT02940912_exc_T30
Drug
apomorphine
NCT02940912_exc_T31
Negation
precluding
NCT02940912_exc_T32
Scope
domperidone or apomorphine
NCT02940912_exc_T33
Scope
precluding treatment with domperidone or apomorphine
NCT02940912_exc_T34
Measurement
QTc
NCT02940912_exc_T36
Value
= 440 ms
NCT02940912_exc_T37
Measurement
QTc
NCT02940912_exc_T38
Value
= 450 ms
NCT02940912_exc_T39
Person
women
NCT02940912_exc_T40
Person
men
NCT02940912_exc_T35
Scope
QTc = 440 ms in men, QTc = 450 ms in women
NCT02940912_exc_T41
Drug
antiemetic neuroleptics
NCT02940912_exc_T42
Drug
Tetrabenazine
NCT02940912_exc_T43
Condition
Excessive alcohol consumption
NCT02940912_exc_T44
Condition
Hypersensitivity
NCT02940912_exc_T45
Drug
apomorphine
NCT02940912_exc_T46
Drug
excipients
NCT02940912_exc_T47
Scope
apomorphine or one of the excipients
NCT02940912_exc_T48
Condition
Respiratory Depression
NCT02940912_exc_T49
Condition
Hepatic impairment
NCT02940912_exc_T50
Condition
Intellectual Disability
NCT02940912_exc_T51
Condition
Dementia