18-80 year, male or female.
Chronic Heart failure subjects with medical history of cardiac disease or other related cardiovascular disease.
Left ventricular ejection fraction (LVEF) less than or equal to (=<) 40 percent (%).
New York Heart Association (NYHA) class of II - IV
NYHA II : Slight limitation of physical activity. Comfortable at rest, but ordinary physical activity results in undue breathlessness, fatigue or palpitation.
NYHA III:Marked limitation of physical activity. Comfortable at rest, but less than ordinary activity causes undue breathlessness, fatigue or palpitation.
NYHA IV:Unable to carry on any physical activity without discomfort. Symptoms at rest can be present. If any physical activity is undertaken, discomfort increased.
Signed Informed Consent Form (ICF).

NCT03026088_inc_T1
Person
year
NCT03026088_inc_T2
Value
18-80
NCT03026088_inc_T3
Person
male
NCT03026088_inc_T4
Person
female
NCT03026088_inc_T5
Condition
Chronic Heart failure
NCT03026088_inc_T6
Condition
cardiac disease
NCT03026088_inc_T7
Condition
cardiovascular disease
NCT03026088_inc_T8
Qualifier
related
NCT03026088_inc_T9
Scope
cardiac disease or other related cardiovascular disease
NCT03026088_inc_T10
Measurement
Left ventricular ejection fraction
NCT03026088_inc_T11
Measurement
LVEF
NCT03026088_inc_T12
Value
ss than or equal to (  percent 
NCT03026088_inc_T13
Value
) .
NCT03026088_inc_T14
Measurement
 York Heart Association ( ss of
NCT03026088_inc_T15
Value
II - IV
NCT03026088_inc_T16
Measurement
NYHA