More than three doses of any opioid within one week of surgery
Pregnancy
Prisoners
Unable to provide consent
Emergency surgery
Chronic kidney disease stage 5 (GFR < 15 ml/min)
Severe hepatic impairment
Recent myocardial infarction (within the last 3 months)

NCT02789111_exc_T1
Multiplier
More than three doses
NCT02789111_exc_T2
Drug
opioid
NCT02789111_exc_T3
Temporal
within one week of surgery
NCT02789111_exc_T4
Reference_point
surgery
NCT02789111_exc_T5
Condition
Pregnancy
NCT02789111_exc_T6
Person
Prisoners
NCT02789111_exc_T8
Procedure
Emergency surgery
NCT02789111_exc_T9
Condition
Chronic kidney disease
NCT02789111_exc_T10
Qualifier
stage 5
NCT02789111_exc_T11
Measurement
GFR
NCT02789111_exc_T12
Value
< 15 ml/min)
NCT02789111_exc_T13
Condition
hepatic impairment
NCT02789111_exc_T14
Qualifier
Severe
NCT02789111_exc_T15
Condition
myocardial infarction
NCT02789111_exc_T16
Temporal
the last 3 months