Any active respiratory, cardiovascular or other disease requiring regular treatment or being otherwise relevant for tolerance of hypoxia or altitude exposure.
Any condition that may interfere with protocol compliance including current heavy smoking (>20 cigarettes per day or >20 pack-years with active smoking during the last 10 years), regular use of alcohol.
Allergy to acetazolamide and other sulfonamides.

NCT03537924_exc_T1
Qualifier
other
NCT03537924_exc_T2
Condition
disease
NCT03537924_exc_T3
Condition
cardiovascular disease
NCT03537924_exc_T4
Condition
respiratory disease
NCT03537924_exc_T5
Qualifier
active
NCT03537924_exc_T6
Mood
requiring
NCT03537924_exc_T7
Procedure
treatment
NCT03537924_exc_T8
Mood
relevant being
NCT03537924_exc_T9
Condition
tolerance
NCT03537924_exc_T10
Condition
hypoxia
NCT03537924_exc_T11
Condition
altitude exposure
NCT03537924_exc_T12
Scope
hypoxia or altitude exposure
NCT03537924_exc_T13
Scope
respiratory, cardiovascular or other disease
NCT03537924_exc_T14
Condition
heavy smoking
NCT03537924_exc_T15
Measurement
cigarettes per day
NCT03537924_exc_T16
Measurement
pack-years
NCT03537924_exc_T17
Condition
active smoking
NCT03537924_exc_T18
Temporal
during the last 10 years
NCT03537924_exc_T19
Value
>20
NCT03537924_exc_T20
Value
>20
NCT03537924_exc_T21
Scope
>20 cigarettes per day or >20 pack-years with active smoking during the last 10 years
NCT03537924_exc_T22
Condition
regular use of alcohol
NCT03537924_exc_T23
Condition
Allergy
NCT03537924_exc_T24
Drug
acetazolamide
NCT03537924_exc_T25
Drug
sulfonamides
NCT03537924_exc_T26
Qualifier
other
NCT03537924_exc_T27
Scope
acetazolamide and other sulfonamides