Biopsy-proven LN Class III/IV±V (ISN/RPS 2003), with biopsy performed within 12 weeks of randomization.
Positive anti-dsDNA.
Active LN with proteinuria (urine protein/creatinine ratio >1.0 or 24-hr urine protein >1.0 g at baseline), with or without hematuria.
Both 'incident' (i.e. new) patients and 'flare' patients can be included.

NCT02630628_inc_T1
Condition
LN
NCT02630628_inc_T2
Qualifier
Class III/IV±V
NCT02630628_inc_T3
Procedure
biopsy
NCT02630628_inc_T4
Temporal
within 12 weeks
NCT02630628_inc_T5
Measurement
anti-dsDNA
NCT02630628_inc_T6
Value
Positive
NCT02630628_inc_T7
Condition
LN
NCT02630628_inc_T8
Condition
proteinuria
NCT02630628_inc_T9
Measurement
urine protein/creatinine ratio
NCT02630628_inc_T10
Value
>1.0
NCT02630628_inc_T11
Measurement
24-hr urine protein
NCT02630628_inc_T12
Value
>1.0 g
NCT02630628_inc_T13
Scope
urine protein/creatinine ratio >1.0 or 24-hr urine protein >1.0 g
NCT02630628_inc_T14
Qualifier
Active
NCT02630628_inc_T15
Condition
hematuria