history of significant bleeding (i.e. bleeding which required intervention or hospitalization), even in the absence of anticoagulation treatment at the time of the bleeding event, or
a cardioembolic event, which occurred on anticoagulation, or
a high risk profile of the patient, defined as a CHA2DS2-VASc score = 3 and a HAS-BLED score = 2

NCT02426944_inc_T1
Condition
bleeding
NCT02426944_inc_T2
Qualifier
significant
NCT02426944_inc_T3
Condition
bleeding
NCT02426944_inc_T4
Procedure
intervention
NCT02426944_inc_T5
Procedure
hospitalization
NCT02426944_inc_T6
Scope
intervention or hospitalization
NCT02426944_inc_T7
Scope
bleeding which required intervention or hospitalization
NCT02426944_inc_T8
Scope
significant bleeding
NCT02426944_inc_T9
Condition
cardioembolic event
NCT02426944_inc_T10
Drug
anticoagulation
NCT02426944_inc_T11
Temporal
occurred on anticoagulation
NCT02426944_inc_T12
Measurement
CHA2DS2-VASc score
NCT02426944_inc_T13
Value
= 3
NCT02426944_inc_T14
Measurement
HAS-BLED score
NCT02426944_inc_T15
Value
= 2
NCT02426944_inc_T16
Condition
high risk profile
NCT02426944_inc_T17
Scope
CHA2DS2-VASc score = 3 and a HAS-BLED score = 2