Is not a habitual wearer of Avaira sphere lenses 
Has a CL prescription outside the range of the available parameters of the study lenses. 
Has a spectacle cylinder ≥1.00D of cylinder in either eye. 
Has a history of not achieving comfortable CL wear (5 days per week; > 8 hours/day) 
Has contact lens best corrected distance vision worse than 20/25 (0.10 logMAR) in either eye. 
Presence of clinically significant (grade 2-4) anterior segment abnormalities 
Presence of ocular or systemic disease or need of medications which might interfere with contact lens wear. 
Slit lamp findings that would contraindicate contact lens wear such as: 
Pathological dry eye or associated findings 
Pterygium, pinguecula, or corneal scars within the visual axis 
Neovascularization > 0.75 mm in from of the limbus 
Giant papillary conjunctivitis (GCP) worse than grade 1 
Anterior uveitis or iritis (past or present) 
Seborrheic eczema, Seborrheic conjunctivitis 
History of corneal ulcers or fungal infections 
Poor personal hygiene 
Has a known history of corneal hypoesthesia (reduced corneal sensitivity) 
Has aphakia, keratoconus or a highly irregular cornea. 
Has Presbyopia or has dependence on spectacles for near work over the contact lenses. 
Has undergone corneal refractive surgery. 
Is participating in any other type of eye related clinical or research study       
    

NCT02406495_exc_T1
Device
Avaira sphere lenses
NCT02406495_exc_T2
Device
CL prescription
NCT02406495_exc_T5
Qualifier
outside the range of the available parameters of the study lenses
NCT02406495_exc_T6
Device
spectacle cylinder
NCT02406495_exc_T7
Value
≥1.00D
NCT02406495_exc_T8
Observation
history
NCT02406495_exc_T9
Condition
comfortable CL wear
NCT02406495_exc_T10
Negation
not
NCT02406495_exc_T11
Temporal
5 days per week
NCT02406495_exc_T12
Temporal
> 8 hours/day
NCT02406495_exc_T13
Measurement
contact lens best corrected distance vision
NCT02406495_exc_T14
Value
worse than 20/25 in either eye
NCT02406495_exc_T15
Value
worse than 0.10 logMAR in either eye
NCT02406495_exc_T16
Scope
worse than 20/25 (0.10 logMAR) in either eye
NCT02406495_exc_T17
Qualifier
clinically significant
NCT02406495_exc_T19
Qualifier
grade 2-4
NCT02406495_exc_T20
Value
2-4
NCT02406495_exc_T21
Condition
anterior segment abnormalities
NCT02406495_exc_T23
Condition
systemic disease
NCT02406495_exc_T24
Condition
ocular disease
NCT02406495_exc_T25
Condition
need of medications
NCT02406495_exc_T29
Qualifier
might interfere with contact lens wear
NCT02406495_exc_T31
Scope
ocular or systemic disease or need of medications
NCT02406495_exc_T32
Procedure
Slit lamp
NCT02406495_exc_T33
Value
findings
NCT02406495_exc_T35
Condition
contraindicate contact lens
NCT02406495_exc_T38
Condition
Pathological dry eye
NCT02406495_exc_T39
Condition
associated findings
NCT02406495_exc_T40
Condition
Pterygium
NCT02406495_exc_T41
Condition
pinguecula
NCT02406495_exc_T42
Condition
corneal scars
NCT02406495_exc_T43
Qualifier
within the visual axis
NCT02406495_exc_T44
Condition
Neovascularization
NCT02406495_exc_T45
Value
> 0.75 mm in from of the limbus
NCT02406495_exc_T46
Condition
Giant papillary conjunctivitis (GCP)
NCT02406495_exc_T47
Qualifier
worse than grade 1
NCT02406495_exc_T48
Condition
Anterior uveitis
NCT02406495_exc_T49
Condition
iritis
NCT02406495_exc_T50
Temporal
past
NCT02406495_exc_T51
Temporal
present
NCT02406495_exc_T52
Scope
past or present
NCT02406495_exc_T53
Scope
Anterior uveitis or iritis
NCT02406495_exc_T54
Condition
Seborrheic eczema
NCT02406495_exc_T55
Condition
Seborrheic conjunctivitis
NCT02406495_exc_T56
Condition
corneal ulcers
NCT02406495_exc_T57
Condition
fungal infections
NCT02406495_exc_T58
Observation
History
NCT02406495_exc_T59
Condition
Poor personal hygiene
NCT02406495_exc_T60
Condition
corneal hypoesthesia
NCT02406495_exc_T61
Condition
reduced corneal sensitivity
NCT02406495_exc_T62
Observation
history
NCT02406495_exc_T63
Condition
aphakia
NCT02406495_exc_T64
Condition
keratoconus
NCT02406495_exc_T65
Condition
highly irregular cornea
NCT02406495_exc_T66
Condition
Presbyopia
NCT02406495_exc_T67
Condition
dependence on spectacles for near work
NCT02406495_exc_T68
Procedure
corneal refractive surgery