Preoperative Hemoglobin <U+2266>11 g/dl
History of infection or intraarticular fracture of the affective hip
Renal function deficiency (GFR <30 ml/min/1.73m2)
Elevated liver enzyme (aspartate transaminase (AST)/ alanine transaminase(ALT) level are more than twice normal range) , history of liver cirrhosis, impaired liver function(elevated total bilirubin level) and coagulopathy (including long-term use anticoagulant)
History of deep vein thrombosis, ischemic heart disease or stroke
Contraindications of tranexamic acid, floseal, or rivaroxaban
Allergy to tranexamic acid, floseal, rivaroxaban, or the excipients
History of heparin-induced thrombocytopenia (HIT)
Coagulopathy or bleeding tendency caused by organ dysfunction, such as cirrhosis, bone marrow suppression etc.
Patient who have active bleeding disorder, such as intracranial hemorrhage, upper gastrointestinal bleeding, hematuria.
Patients with known allergies to materials of bovine origin.

NCT03623789_exc_T1
Temporal
Preoperative
NCT03623789_exc_T2
Measurement
Hemoglobin
NCT03623789_exc_T3
Value
<U+2266>11 g/dl
NCT03623789_exc_T4
Condition
infection
NCT03623789_exc_T5
Condition
intraarticular fracture
NCT03623789_exc_T6
Qualifier
affective hip
NCT03623789_exc_T7
Scope
infection or intraarticular fracture
NCT03623789_exc_T8
Observation
History
NCT03623789_exc_T9
Condition
Renal function deficiency
NCT03623789_exc_T10
Measurement
GFR
NCT03623789_exc_T11
Value
<30 ml/min/1.73m2
NCT03623789_exc_T12
Scope
GFR <30 ml/min/1.73m2
NCT03623789_exc_T13
Measurement
liver enzyme
NCT03623789_exc_T14
Value
Elevated
NCT03623789_exc_T15
Measurement
aspartate transaminase (AST)/ alanine transaminase(ALT) level
NCT03623789_exc_T16
Value
more than twice normal range
NCT03623789_exc_T17
Observation
history
NCT03623789_exc_T18
Condition
liver cirrhosis
NCT03623789_exc_T19
Condition
impaired liver function
NCT03623789_exc_T20
Value
elevated
NCT03623789_exc_T21
Measurement
total bilirubin level
NCT03623789_exc_T22
Condition
coagulopathy
NCT03623789_exc_T23
Multiplier
long-term use
NCT03623789_exc_T24
Drug
anticoagulant
NCT03623789_exc_T25
Scope
long-term use anticoagulant
NCT03623789_exc_T26
Condition
deep vein thrombosis
NCT03623789_exc_T27
Condition
ischemic heart disease
NCT03623789_exc_T28
Condition
stroke
NCT03623789_exc_T29
Condition
Contraindications
NCT03623789_exc_T30
Drug
tranexamic acid
NCT03623789_exc_T31
Drug
floseal
NCT03623789_exc_T32
Drug
rivaroxaban
NCT03623789_exc_T33
Scope
tranexamic acid, floseal, or rivaroxaban
NCT03623789_exc_T34
Condition
Allergy
NCT03623789_exc_T35
Drug
tranexamic acid
NCT03623789_exc_T36
Drug
floseal
NCT03623789_exc_T37
Drug
rivaroxaban
NCT03623789_exc_T38
Drug
excipients
NCT03623789_exc_T39
Scope
tranexamic acid, floseal, rivaroxaban, or the excipients
NCT03623789_exc_T40
Condition
heparin-induced thrombocytopenia (HIT)
NCT03623789_exc_T41
Observation
History
NCT03623789_exc_T42
Condition
Coagulopathy
NCT03623789_exc_T43
Condition
bleeding tendency
NCT03623789_exc_T44
Condition
organ dysfunction
NCT03623789_exc_T45
Condition
cirrhosis
NCT03623789_exc_T46
Condition
bone marrow suppression
NCT03623789_exc_T47
Scope
cirrhosis, bone marrow suppression
NCT03623789_exc_T48
Scope
Coagulopathy or bleeding tendency
NCT03623789_exc_T49
Qualifier
active
NCT03623789_exc_T50
Condition
bleeding disorder
NCT03623789_exc_T51
Condition
intracranial hemorrhage
NCT03623789_exc_T52
Condition
upper gastrointestinal bleeding
NCT03623789_exc_T53
Condition
hematuria
NCT03623789_exc_T54
Scope
intracranial hemorrhage, upper gastrointestinal bleeding, hematuria
NCT03623789_exc_T55
Condition
allergies
NCT03623789_exc_T56
Drug
materials of bovine origin