History or presence of any clinically significant disease or disorder 
Any condition or disease that would render the subject unsuitable for the study, place the subject at undue risk or interfere with the ability of the subject to complete the study in the opinion of the investigator 
History of clinically significant hypersensitivity or allergic drug reactions 
Any suspicion or history of alcohol abuse and/or consumption of other drugs of abuse 
Regular smoker (> 5 cigarettes, > 1 pipeful or > 1 cigar per day) 
Positive for hepatitis B, hepatitis C or HIV infection 
Dietary restrictions that would prohibit the consumption of standardized meals 
Participation in an investigational drug or device study within 90 days prior to screening, as calculated from the follow-up from the previous study       
    

NCT01711801_exc_T1
Qualifier
clinically significant
NCT01711801_exc_T2
Condition
clinically significant disease
NCT01711801_exc_T3
Condition
clinically significant disorder
NCT01711801_exc_T6
Observation
History
NCT01711801_exc_T9
Qualifier
clinically significant
NCT01711801_exc_T11
Condition
hypersensitivity
NCT01711801_exc_T12
Condition
allergic drug reactions
NCT01711801_exc_T13
Condition
alcohol abuse
NCT01711801_exc_T14
Observation
suspicion
NCT01711801_exc_T15
Observation
history
NCT01711801_exc_T16
Scope
suspicion or history
NCT01711801_exc_T17
Condition
consumption of other drugs of abuse
NCT01711801_exc_T18
Scope
alcohol abuse and/or consumption of other drugs of abuse
NCT01711801_exc_T19
Condition
Regular smoker
NCT01711801_exc_T20
Multiplier
> 5
NCT01711801_exc_T21
Observation
cigarettes
NCT01711801_exc_T23
Multiplier
> 1 per day
NCT01711801_exc_T24
Observation
cigar
NCT01711801_exc_T22
Multiplier
> 1
NCT01711801_exc_T25
Observation
pipeful
NCT01711801_exc_T26
Scope
> 5 cigarettes, > 1 pipeful or > 1 cigar per day
NCT01711801_exc_T27
Measurement
hepatitis B
NCT01711801_exc_T28
Value
Positive
NCT01711801_exc_T29
Measurement
hepatitis C
NCT01711801_exc_T30
Condition
HIV infection
NCT01711801_exc_T31
Condition
Dietary restrictions
NCT01711801_exc_T32
Qualifier
would prohibit the consumption of standardized meals