Male or female =18 years of age at Visit 1
Documentation of a CF diagnosis
Enrolled in the Cystic Fibrosis Foundation National Patient Registry (CFFNPR) prior to Visit 1 (US sites only)
At the time of Visit 1, there is a plan to initiate IV antibiotics for a pulmonary exacerbation
Performed spirometry at Visit 1 and Visit 2 and willing to perform spirometry at Visit 3
Completed the CRISS questionnaire at Visit 1 and Visit 2 and willing to complete the Cystic Fibrosis Respiratory Symptoms Diary (CFRSD) questionnaire at Visit 3
Willing to adhere to a specific treatment duration determined by initial response to treatment and subsequent randomization
Willing to return for follow up Visit 3
Written informed consent obtained from the subject or subject's legal representative

NCT02781610_inc_T1
Person
Male
NCT02781610_inc_T2
Person
female
NCT02781610_inc_T3
Person
age
NCT02781610_inc_T4
Value
=18 years
NCT02781610_inc_T5
Temporal
at Visit 1
NCT02781610_inc_T6
Reference_point
Visit 1
NCT02781610_inc_T7
Condition
CF
NCT02781610_inc_T10
Drug
IV antibiotics
NCT02781610_inc_T11
Condition
pulmonary exacerbation
NCT02781610_inc_T12
Temporal
At the time of Visit 1
NCT02781610_inc_T13
Reference_point
Visit 1
NCT02781610_inc_T14
Procedure
spirometry
NCT02781610_inc_T15
Temporal
at Visit 1
NCT02781610_inc_T16
Temporal
is t 2 and
NCT02781610_inc_T17
Temporal
at Visit 3
NCT02781610_inc_T18
Scope
at Visit 1 and Visit 2
NCT02781610_inc_T8
Mood
willing to perform
NCT02781610_inc_T9
Procedure
spirometry
NCT02781610_inc_T23
Reference_point
Visit 1
NCT02781610_inc_T24
Reference_point
Visit 2
NCT02781610_inc_T25
Reference_point
Visit 3
NCT02781610_inc_T19
Procedure
CRISS questionnaire
NCT02781610_inc_T26
Temporal
at Visit 1
NCT02781610_inc_T27
Temporal
si  2 an
NCT02781610_inc_T28
Reference_point
Visit 1
NCT02781610_inc_T29
Reference_point
Visit 2
NCT02781610_inc_T30
Scope
at Visit 1 and Visit 2
NCT02781610_inc_T31
Mood
willing to complete
NCT02781610_inc_T32
Procedure
Cystic Fibrosis Respiratory Symptoms Diary (CFRSD) questionnaire
NCT02781610_inc_T33
Temporal
at Visit 3
NCT02781610_inc_T34
Reference_point
Visit 3
NCT02781610_inc_T35
Observation
Enrolled in the Cystic Fibrosis Foundation National Patient Registry (CFFNPR)
NCT02781610_inc_T36
Temporal
prior to Visit 1
NCT02781610_inc_T37
Reference_point
Visit 1
NCT02781610_inc_T38
Visit
US sites
NCT02781610_inc_T20
Mood
Willing to
NCT02781610_inc_T21
Mood
Willing to
NCT02781610_inc_T41
Procedure
follow up Visit 3
NCT02781610_inc_T22
Observation
Written informed consent
NCT02781610_inc_T40
Qualifier
from the subject
NCT02781610_inc_T42
Qualifier
 subjec s legal representative
NCT02781610_inc_T43
Scope
from the subject or subject's legal representative