Children who are uncooperative and difficult to manage, have major systemic diseases, or are on long-term medication will be excluded.       
    

NCT02019160_exc_T1
Condition
uncooperative
NCT02019160_exc_T2
Observation
difficult to manage
NCT02019160_exc_T4
Condition
systemic diseases
NCT02019160_exc_T5
Qualifier
major
NCT02019160_exc_T6
Temporal
long-term
NCT02019160_exc_T7
Drug
medication
NCT02019160_exc_T8
Scope
uncooperative and difficult to manage