1) age 50-70 
2) stroke within the past 6 to 60 months, 
3) major depressive disorder (PHQ-9 > 10) and diagnosed using the Structured Clinical Interview for Depression (SCID) according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), 
4) residual paresis in the lower extremity (Fugl-Meyer LE motor score <34), 
5) ability to walk without assistance and without an AFO on the treadmill ≥ 30 seconds at speeds ranging from 0.2-0.8 m/s, 
6) no antidepressant medications or clinically able to discontinue medications, 
7) HRSD question #9 regarding suicide <2, 
8) provision of informed consent. In addition, all subjects who meet criteria for the training portion must complete an exercise tolerance test and be cleared for participation by the study cardiologist. 

NCT03056287_inc_T1
Person
age
NCT03056287_inc_T2
Value
50-70
NCT03056287_inc_T3
Condition
stroke
NCT03056287_inc_T4
Temporal
within the past 6 to 60 months
NCT03056287_inc_T5
Condition
major depressive disorder
NCT03056287_inc_T6
Measurement
PHQ-9
NCT03056287_inc_T7
Value
> 10
NCT03056287_inc_T8
Procedure
Structured Clinical Interview for Depression (SCID) according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)
NCT03056287_inc_T9
Condition
residual paresis
NCT03056287_inc_T10
Qualifier
lower extremity
NCT03056287_inc_T11
Measurement
Fugl-Meyer LE motor score
NCT03056287_inc_T12
Value
<34
NCT03056287_inc_T13
Condition
ability to walk without assistance
NCT03056287_inc_T14
Measurement
AFO on the treadmill
NCT03056287_inc_T15
Value
≥ 30 seconds
NCT03056287_inc_T16
Negation
without
NCT03056287_inc_T17
Qualifier
speeds
NCT03056287_inc_T18
Value
from 0.2-0.8 m/s
NCT03056287_inc_T19
Drug
antidepressant
NCT03056287_inc_T20
Negation
no
NCT03056287_inc_T21
Condition
clinically able to discontinue medications
NCT03056287_inc_T24
Measurement
HRSD question #9
NCT03056287_inc_T25
Value
<2