An average defecation frequency (DF) of <3 per week based on a 3-week defecation diary (patient-reported)
Meet at least one other criterion of the Rome-IV criteria for idiopathic constipation based on the 3-week defecation diary (1)
Refractory to conservative treatment
Age: 14-80 years
Straining during =25% of defecations
Lumpy or hard stools in =25% of defecations
Sensation of incomplete evacuation for =25% of defecations
Sensation of anorectal obstruction/blockage for =25% of defecations
Manual manoeuvres to facilitate =25% of defecations

NCT02961582_inc_T1
Measurement
average defecation frequency
NCT02961582_inc_T2
Measurement
DF
NCT02961582_inc_T3
Value
<3 per week
NCT02961582_inc_T4
Procedure
3-week defecation diary
NCT02961582_inc_T7
Multiplier
at least one
NCT02961582_inc_T8
Measurement
Rome-IV criteria for idiopathic constipation
NCT02961582_inc_T9
Condition
idiopathic constipation
NCT02961582_inc_T10
Procedure
3-week defecation diary
NCT02961582_inc_T13
Qualifier
other
NCT02961582_inc_T14
Procedure
conservative treatment
NCT02961582_inc_T15
Qualifier
Refractory
NCT02961582_inc_T16
Person
Age
NCT02961582_inc_T17
Value
14-80 years
NCT02961582_inc_T18
Condition
Straining
NCT02961582_inc_T21
Multiplier
=25%
NCT02961582_inc_T22
Condition
defecations
NCT02961582_inc_T23
Observation
hard stools
NCT02961582_inc_T24
Observation
 or  s in =
NCT02961582_inc_T25
Condition
defecations
NCT02961582_inc_T26
Multiplier
=25%
NCT02961582_inc_T29
Condition
Sensation of incomplete evacuation
NCT02961582_inc_T30
Multiplier
=25%
NCT02961582_inc_T31
Condition
defecations
NCT02961582_inc_T27
Condition
defecations
NCT02961582_inc_T28
Multiplier
=25%
NCT02961582_inc_T32
Condition
Sensation of anorectal obstruction
NCT02961582_inc_T33
Condition
on of anorectal obstru e for =2
NCT02961582_inc_T35
Condition
defecations
NCT02961582_inc_T36
Multiplier
=25%
NCT02961582_inc_T37
Procedure
Manual manoeuvres
NCT02961582_inc_T11
Condition
criterion
NCT02961582_inc_T12
Scope
Sensation of anorectal obstruction/blockage
NCT02961582_inc_T34
Scope
Lumpy or hard stools
NCT02961582_inc_T5
Qualifier
patient-reported