1. Have dementia or delirium (as determined by the palliative care specialist) at study entry. 
2. Are pregnant 
3. Have been taking corticosteroids for longer than 48 hours. 
4. Have pulmonary edema, ascites or pitting edema on clinical examination. 
5. Are unable to walk. 
6. Have a history of serious adverse gastrointestinal events (i.e., bleeding or perforation),history of a coagulopathy or current anti-coagulant use. 
7. Have an ALT/AST>3x upper limit of normal. 
8. Patients on methotrexate. 
9. Patients taking melatonin receptor agonists (such as Rozerem® [ramelteon]).       
    

NCT00625742_exc_T1
Condition
dementia
NCT00625742_exc_T2
Condition
delirium
NCT00625742_exc_T3
Temporal
at study entry
NCT00625742_exc_T4
Scope
dementia or delirium
NCT00625742_exc_T5
Condition
pregnant
NCT00625742_exc_T6
Drug
corticosteroids
NCT00625742_exc_T7
Temporal
longer than 48 hours
NCT00625742_exc_T8
Condition
pulmonary edema
NCT00625742_exc_T9
Condition
ascites
NCT00625742_exc_T10
Condition
pitting edema
NCT00625742_exc_T11
Condition
unable to walk
NCT00625742_exc_T12
Observation
history
NCT00625742_exc_T13
Condition
adverse gastrointestinal events
NCT00625742_exc_T14
Qualifier
serious
NCT00625742_exc_T15
Condition
bleeding
NCT00625742_exc_T16
Condition
perforation
NCT00625742_exc_T17
Scope
bleeding or perforation
NCT00625742_exc_T18
Condition
coagulopathy
NCT00625742_exc_T19
Observation
history
NCT00625742_exc_T20
Drug
anti-coagulant
NCT00625742_exc_T21
Temporal
current
NCT00625742_exc_T22
Measurement
ALT/AST
NCT00625742_exc_T23
Value
>3x upper limit of normal
NCT00625742_exc_T24
Drug
methotrexate
NCT00625742_exc_T25
Drug
melatonin receptor agonists
NCT00625742_exc_T26
Drug
Rozerem
NCT00625742_exc_T27
Drug
ramelteon