With severe systemic alteration;
In the use of antibiotics and anti-inflammatories in the last three months;
With periodontium with periodontal parameters different from those established in the inclusion criteria.
Individuals with clinical signs of parafunctional habits;
Smoking;
Individuals who have performed other restorations in the last 12 months;
Pregnant women and infants;
Periodontal sites that presented bleeding during crevicular fluid collection or sites that prevent proper collection of clinical parameters.

NCT03637946_exc_T1
Condition
systemic alteration
NCT03637946_exc_T2
Qualifier
severe
NCT03637946_exc_T3
Drug
antibiotics
NCT03637946_exc_T4
Drug
anti-inflammatories
NCT03637946_exc_T5
Temporal
in the last three months
NCT03637946_exc_T6
Scope
antibiotics and anti-inflammatories
NCT03637946_exc_T8
Condition
clinical signs of parafunctional habits
NCT03637946_exc_T9
Observation
Smoking
NCT03637946_exc_T10
Procedure
other restorations
NCT03637946_exc_T11
Temporal
in the last 12 months
NCT03637946_exc_T12
Condition
Pregnant
NCT03637946_exc_T13
Person
women
NCT03637946_exc_T14
Person
infants
NCT03637946_exc_T15
Scope
Pregnant women