Patients are able to provide signed and dated written informed consent prior to any study specific procedures.
Women are post-menopausal (defined as at least 1 year post cessation of menses) and aged = 45 and = 70 years. Males are aged = 40 years and = 70 years. Patients should have suitable veins for cannulation or repeated venipuncture.
Patients are diagnosed with T2DM for at least the last 6 months.
Patients are on no other anti-diabetic drug treatment, or on stable maximum 3000 mg daily dose metformin treatment and/or on stable dose of a DPPIV inhibitor treatment for at least the last 3 months5. HbA1c levels =6.0% (=42 mmol/mol) and =9.0% (75 mmol/mol).
Have a body mass index (BMI) = 35 kg/m2.

NCT03338855_inc_T2
Person
Women
NCT03338855_inc_T3
Condition
post-menopausal
NCT03338855_inc_T4
Condition
T2DM
NCT03338855_inc_T5
Temporal
as at least 1 year post cessation of menses
NCT03338855_inc_T6
Reference_point
cessation of menses
NCT03338855_inc_T7
Person
aged
NCT03338855_inc_T8
Value
= 45 and = 70 years
NCT03338855_inc_T9
Person
Males
NCT03338855_inc_T10
Person
aged
NCT03338855_inc_T11
Value
= 40 years and = 70 years
NCT03338855_inc_T13
Scope
post-menopausal (defined as at least 1 year post cessation of menses) and aged = 45 and = 70 years
NCT03338855_inc_T14
Scope
aged = 40 years and = 70 years
NCT03338855_inc_T15
Temporal
for at least the last 6 months
NCT03338855_inc_T16
Procedure
anti-diabetic drug treatment
NCT03338855_inc_T17
Negation
no
NCT03338855_inc_T18
Qualifier
other
NCT03338855_inc_T19
Qualifier
stable
NCT03338855_inc_T20
Multiplier
maximum 3000 mg daily dose
NCT03338855_inc_T21
Drug
metformin
NCT03338855_inc_T22
Qualifier
stable dose
NCT03338855_inc_T23
Drug
DPPIV inhibitor
NCT03338855_inc_T24
Temporal
for at least the last 3 months
NCT03338855_inc_T25
Measurement
HbA1c levels
NCT03338855_inc_T26
Value
=6.0%
NCT03338855_inc_T27
Value
=42 mmol/mol
NCT03338855_inc_T28
Value
=9.0%
NCT03338855_inc_T29
Value
75 mmol/mol
NCT03338855_inc_T30
Scope
=6.0% (=42 mmol/mol) and =9.0% (75 mmol/mol)
NCT03338855_inc_T31
Measurement
body mass index (BMI)
NCT03338855_inc_T32
Value
= 35 kg/m2