Research exemption requested
History of PCV-13 vaccination
History of cochlear implant
Cerebrospinal Fluid (CSF) leak
Congestive Heart Failure (CHF)
Diabetes Mellitus (DM)
Chronic Kidney Disease (CKD)
Human Immunodeficiency Virus (HIV)
Common Variable Immune Deficiency (CVID)
Patients who have received the PPSV23 vaccine in the last 5 years
Women who are pregnant will also be excluded from the study by performing 2 point of care urine pregnancy tests ( prior to vaccinations)

NCT03260790_exc_T1
Observation
Research exemption requested
NCT03260790_exc_T2
Observation
History
NCT03260790_exc_T3
Procedure
PCV-13 vaccination
NCT03260790_exc_T4
Observation
History
NCT03260790_exc_T5
Device
cochlear implant
NCT03260790_exc_T6
Condition
Cerebrospinal Fluid (CSF) leak
NCT03260790_exc_T7
Condition
Congestive Heart Failure (CHF)
NCT03260790_exc_T8
Condition
Diabetes Mellitus (DM)
NCT03260790_exc_T9
Condition
Chronic Kidney Disease (CKD)
NCT03260790_exc_T10
Condition
Human Immunodeficiency Virus (HIV)
NCT03260790_exc_T11
Condition
Common Variable Immune Deficiency (CVID)
NCT03260790_exc_T12
Drug
PPSV23 vaccine
NCT03260790_exc_T13
Temporal
in the last 5 years
NCT03260790_exc_T14
Person
Women
NCT03260790_exc_T15
Condition
pregnant
NCT03260790_exc_T16
Procedure
point of care urine pregnancy tests
NCT03260790_exc_T17
Multiplier
2
NCT03260790_exc_T18
Temporal
prior to vaccinations
NCT03260790_exc_T19
Procedure
vaccinations
NCT03260790_exc_T20
Reference_point
vaccinations