Presence of organic pathology identified by upper endoscopy or other investigations
Presence of sliding hiatus hernia as defined by flap valve grade IV disruption of morphology at gastro-esophageal junction
Concurrent medications that affect gastrointestinal motility
Presence of acid reflux or heartburn symptoms of more than twice a month
History of gastric surgery
H. pylori infection
Use of PPI or NSAID in the past 4 weeks
Pregnancy
Known hypersensitivity to PPI

NCT01349413_exc_T1
Procedure
upper endoscopy
NCT01349413_exc_T2
Condition
organic pathology
NCT01349413_exc_T3
Procedure
investigations
NCT01349413_exc_T4
Scope
upper endoscopy or other investigations
NCT01349413_exc_T5
Condition
hiatus hernia
NCT01349413_exc_T6
Qualifier
sliding
NCT01349413_exc_T7
Measurement
lap valve isruption of morphology
NCT01349413_exc_T8
Value
grade IV
NCT01349413_exc_T9
Qualifier
at gastro-esophageal junction
NCT01349413_exc_T10
Drug
medications
NCT01349413_exc_T11
Condition
gastrointestinal motility
NCT01349413_exc_T12
Condition
acid reflux
NCT01349413_exc_T13
Condition
heartburn symptoms
NCT01349413_exc_T14
Temporal
more than twice a month
NCT01349413_exc_T15
Scope
acid reflux or heartburn symptoms
NCT01349413_exc_T16
Procedure
gastric surgery
NCT01349413_exc_T17
Condition
H. pylori infection
NCT01349413_exc_T18
Drug
PPI
NCT01349413_exc_T19
Drug
NSAID
NCT01349413_exc_T20
Temporal
in the past 4 weeks
NCT01349413_exc_T21
Scope
PPI or NSAID
NCT01349413_exc_T22
Condition
Pregnancy
NCT01349413_exc_T23
Condition
hypersensitivity
NCT01349413_exc_T24
Drug
PPI