Preoperative renal failure (defined as a serum creatinine > 2.0 mg/dL.)
American Society of Anesthesiologists Physical Status IV or V
Pulmonary disease necessitating home oxygen therapy
Allergy to methadone, hydromorphone, or ketamine
Preoperative recent history of opioid or alcohol abuse
Significant liver disease
Inability to use a PCA device or speak the English language

NCT02827526_exc_T1
Temporal
Preoperative
NCT02827526_exc_T2
Condition
renal failure
NCT02827526_exc_T3
Measurement
serum creatinine
NCT02827526_exc_T4
Value
> 2.0 mg/dL
NCT02827526_exc_T5
Scope
serum creatinine > 2.0 mg/dL
NCT02827526_exc_T6
Measurement
American Society of Anesthesiologists Physical Status
NCT02827526_exc_T7
Value
IV or V
NCT02827526_exc_T8
Condition
Pulmonary disease
NCT02827526_exc_T9
Procedure
home oxygen therapy
NCT02827526_exc_T10
Drug
methadone
NCT02827526_exc_T11
Drug
hydromorphone
NCT02827526_exc_T12
Drug
ketamine
NCT02827526_exc_T13
Temporal
Preoperative
NCT02827526_exc_T14
Temporal
recent
NCT02827526_exc_T15
Observation
history
NCT02827526_exc_T16
Condition
alcohol abuse
NCT02827526_exc_T17
Condition
id or e
Sig
NCT02827526_exc_T18
Scope
opioid or alcohol abuse
NCT02827526_exc_T19
Qualifier
Significant
NCT02827526_exc_T20
Condition
liver disease
NCT02827526_exc_T21
Device
PCA device
NCT02827526_exc_T22
Observation
Inability to use
NCT02827526_exc_T23
Observation
ity to use a the English language