Healthy male and/or female subjects between the ages of 18 and 55 years, and a body mass index (BMI) of ≥ 18 and ≤ 33 kg/m2 with body weight ≥ 50 and ≤ 90 kg at screening. 
Females must have been surgically sterilized (hysterectomy, bilateral oophorectomy, or bilateral salpingo-oophorectomy; proper documentation required) at least 6 months before screening, or be postmenopausal (defined as 24 consecutive months without menses before screening, with a follicle-stimulating hormone [FSH] level of > 40 IU/L at screening). 

NCT02934269_inc_T1
Person
male
NCT02934269_inc_T2
Condition
Healthy
NCT02934269_inc_T3
Person
female
NCT02934269_inc_T4
Person
ages
NCT02934269_inc_T5
Value
between 18 and 55 years
NCT02934269_inc_T6
Measurement
body mass index (BMI)
NCT02934269_inc_T7
Value
≥ 18 and ≤ 33 kg/m2
NCT02934269_inc_T8
Measurement
body weight
NCT02934269_inc_T9
Value
≥ 50 and ≤ 90 kg
NCT02934269_inc_T10
Temporal
at screening
NCT02934269_inc_T11
Reference_point
screening
NCT02934269_inc_T12
Scope
body mass index (BMI) of ≥ 18 and ≤ 33 kg/m2 with body weight ≥ 50 and ≤ 90 kg
NCT02934269_inc_T13
Person
Females
NCT02934269_inc_T14
Condition
surgically sterilized
NCT02934269_inc_T15
Procedure
hysterectomy
NCT02934269_inc_T16
Procedure
bilateral oophorectomy
NCT02934269_inc_T17
Procedure
bilateral salpingo-oophorectomy
NCT02934269_inc_T18
Temporal
at least 6 months before
NCT02934269_inc_T19
Reference_point
screening
NCT02934269_inc_T20
Scope
hysterectomy, bilateral oophorectomy, or bilateral salpingo-oophorectomy
NCT02934269_inc_T21
Condition
postmenopausal
NCT02934269_inc_T22
Temporal
24 consecutive months
NCT02934269_inc_T23
Condition
menses
NCT02934269_inc_T24
Negation
without
NCT02934269_inc_T25
Temporal
before screening
NCT02934269_inc_T26
Reference_point
screening
NCT02934269_inc_T27
Measurement
follicle-stimulating hormone [FSH]
NCT02934269_inc_T28
Value
> 40 IU/L
NCT02934269_inc_T29
Temporal
at screening
NCT02934269_inc_T30
Reference_point
screening
NCT02934269_inc_T31
Scope
24 consecutive months without menses before screening, with a follicle-stimulating hormone [FSH] level of > 40 IU/L at screening
NCT02934269_inc_T32
Scope
surgically sterilized (hysterectomy, bilateral oophorectomy, or bilateral salpingo-oophorectomy; proper documentation required) at least 6 months before screening, or be postmenopausal (defined as 24 consecutive months without menses before screening, with a follicle-stimulating hormone [FSH] level of > 40 IU/L at screening)