Evidence of concomitant infection on exam or gram stain (i.e. herpes, both bacteria and acanthamoeba on gram stain)
Impending or frank perforation at recruitment
Involvement of sclera at presentation
Non-infectious or autoimmune keratitis
History of corneal transplantation or recent intraocular surgery
No light perception in the affected eye
Pinhole visual acuity worse than 20/200 in the unaffected eye
Participants who are decisionally and/or cognitively impaired

NCT02570321_exc_T1
Condition
concomitant infection
NCT02570321_exc_T2
Condition
perforation
NCT02570321_exc_T3
Condition
Involvement of sclera
NCT02570321_exc_T4
Condition
autoimmune keratitis
NCT02570321_exc_T5
Condition
-infectious or atitis
Hi
NCT02570321_exc_T6
Procedure
corneal transplantation
NCT02570321_exc_T7
Procedure
intraocular surgery
NCT02570321_exc_T8
Negation
No
NCT02570321_exc_T9
Condition
light perception
NCT02570321_exc_T10
Measurement
Pinhole visual acuity
NCT02570321_exc_T11
Value
worse than 20/200
NCT02570321_exc_T12
Condition
cognitively impaired