18 years of age or older 
Histologically confirmed diagnosis of melanoma, breast cancer or gynecologic cancer at MSKCC 
Have one of the following disease histories: 
Newly-diagnosed or recurrent (local, regional, metastatic) malignant melanoma or breast cancer patients in whom SLN mapping is indicated 
Residual clinically or radiographically evident tumor, including primary cutaneous and mucosal melanomas 
Prior radiation therapy, chemotherapy, or surgery in patients requiring flap reconstruction in the head and neck region. 
Newly diagnosed patients with previous excisional biopsy. OR 
Newly-diagnosed gynecologic cancer patients in whom SLN mapping and surgical excision is indicated OR 
Normal baseline cardiac function based upon pre-operative evaluation 
At the discretion of the operating surgeon, ANC>1000/mcl and platelets>100,000/mcl. 
At the discretion of the operating surgeon, Bilirubin level of < 2.0 mg/dl in the absence of a history of Gilbert's disease (or pattern consistent with Gilbert's). 
For melanoma patients, If patients have a history of malignancy other than melanoma, and other skin cancers in the past five years, their inclusion is up to the discretion of the physician. 
All patients of childbearing and child-creating age must be using an acceptable form of birth control 
Women who are pre-menopausal must have a negative serum pregnancy test 

NCT02106598_inc_T1
Person
age
NCT02106598_inc_T2
Value
18 years or older
NCT02106598_inc_T3
Condition
melanoma
NCT02106598_inc_T4
Procedure
Histologically
NCT02106598_inc_T5
Value
confirmed
NCT02106598_inc_T6
Condition
breast cancer
NCT02106598_inc_T7
Condition
gynecologic cancer
NCT02106598_inc_T8
Visit
MSKCC
NCT02106598_inc_T10
Condition
malignant melanoma
NCT02106598_inc_T11
Condition
breast cancer
NCT02106598_inc_T12
Qualifier
local
NCT02106598_inc_T13
Qualifier
regional
NCT02106598_inc_T14
Qualifier
metastatic
NCT02106598_inc_T15
Scope
local, regional, metastatic
NCT02106598_inc_T16
Temporal
Newly-diagnosed
NCT02106598_inc_T17
Multiplier
recurrent
NCT02106598_inc_T18
Scope
malignant melanoma or breast cancer
NCT02106598_inc_T19
Scope
Newly-diagnosed or recurrent
NCT02106598_inc_T20
Condition
tumor
NCT02106598_inc_T21
Procedure
radiographically
NCT02106598_inc_T22
Qualifier
Residual
NCT02106598_inc_T23
Value
evident
NCT02106598_inc_T24
Procedure
clinically
NCT02106598_inc_T25
Scope
Residual clinically or radiographically evident
NCT02106598_inc_T26
Condition
primary cutaneous
NCT02106598_inc_T27
Condition
mucosal melanomas
NCT02106598_inc_T28
Scope
primary cutaneous and mucosal melanomas
NCT02106598_inc_T29
Procedure
radiation therapy
NCT02106598_inc_T30
Procedure
chemotherapy
NCT02106598_inc_T31
Procedure
surgery
NCT02106598_inc_T32
Procedure
flap reconstruction
NCT02106598_inc_T33
Condition
requiring flap reconstruction
NCT02106598_inc_T34
Qualifier
head and neck region
NCT02106598_inc_T35
Temporal
Prior
NCT02106598_inc_T36
Procedure
excisional biopsy
NCT02106598_inc_T37
Temporal
previous
NCT02106598_inc_T38
Condition
gynecologic cancer
NCT02106598_inc_T39
Procedure
SLN mapping
NCT02106598_inc_T40
Procedure
surgical excision
NCT02106598_inc_T41
Condition
surgical excision is indicated
NCT02106598_inc_T42
Condition
SLN mapping is indicated
NCT02106598_inc_T43
Measurement
cardiac function
NCT02106598_inc_T44
Value
Normal
NCT02106598_inc_T45
Measurement
baseline
NCT02106598_inc_T46
Procedure
pre-operative evaluation
NCT02106598_inc_T47
Temporal
pre-operative
NCT02106598_inc_T49
Measurement
ANC
NCT02106598_inc_T50
Value
>1000/mcl
NCT02106598_inc_T51
Measurement
platelets
NCT02106598_inc_T52
Value
>100,000/mcl
NCT02106598_inc_T54
Measurement
Bilirubin level
NCT02106598_inc_T55
Value
< 2.0 mg/dl
NCT02106598_inc_T56
Condition
Gilbert's disease
NCT02106598_inc_T57
Negation
in the absence of
NCT02106598_inc_T58
Observation
history
NCT02106598_inc_T59
Condition
melanoma
NCT02106598_inc_T60
Condition
malignancy
NCT02106598_inc_T61
Condition
melanoma
NCT02106598_inc_T62
Negation
other than
NCT02106598_inc_T63
Condition
skin cancers
NCT02106598_inc_T64
Temporal
in the past five years
NCT02106598_inc_T67
Observation
history
NCT02106598_inc_T69
Person
Women
NCT02106598_inc_T70
Condition
pre-menopausal
NCT02106598_inc_T71
Scope
Women who are pre-menopausal
NCT02106598_inc_T72
Measurement
serum pregnancy test
NCT02106598_inc_T73
Value
negative