1. Diagnosis of primary immunodeficiency with established plan to undergo myeloablative or non-myeloablative allogeneic hematopoietic stem cell transplant for treatment thereof or diagnosis of a form of primary immunodeficiency for which hematopoietic stem cell transplantation is not indicated. 
2. Active infection with EBV, CMV, and/or Adenovirus, unable to be successfully controlled with standard therapy. 
3. Steroids less than 0.5 mg/kg/day prednisone 
4. Karnofsky/Lansky score of ≥ 50 
5. ANC greater than 500/µL. 
6. Bilirubin <2x, AST <3x, Serum creatinine <2x upper limit of normal, Hgb >8.0 
7. Pulse oximetry of > 90% on room air 
8. Negative pregnancy test (if female of childbearing potential) 
9. Patient or parent/guardian capable of providing informed consent. 

NCT02510404_inc_T10
Condition
primary immunodeficiency
NCT02510404_inc_T11
Procedure
allogeneic hematopoietic stem cell transplant myeloablative
NCT02510404_inc_T12
Procedure
non-myeloablative allogeneic hematopoietic stem cell transplant
NCT02510404_inc_T13
Condition
primary immunodeficiency
NCT02510404_inc_T14
Procedure
hematopoietic stem cell transplantation
NCT02510404_inc_T15
Negation
not indicated
NCT02510404_inc_T16
Scope
myeloablative or non-myeloablative allogeneic hematopoietic stem cell transplant
NCT02510404_inc_T17
Condition
EBV
NCT02510404_inc_T18
Condition
CMV
NCT02510404_inc_T19
Condition
Adenovirus
NCT02510404_inc_T20
Qualifier
unable to be controlled
NCT02510404_inc_T21
Procedure
standard therapy
NCT02510404_inc_T22
Scope
EBV, CMV, and/or Adenovirus
NCT02510404_inc_T23
Drug
Steroids
NCT02510404_inc_T24
Multiplier
less than 0.5 mg/kg/day
NCT02510404_inc_T25
Drug
prednisone
NCT02510404_inc_T26
Measurement
Karnofsky/Lansky score
NCT02510404_inc_T27
Value
≥ 50
NCT02510404_inc_T28
Measurement
ANC
NCT02510404_inc_T29
Value
greater than 500/µL
NCT02510404_inc_T30
Measurement
Bilirubin
NCT02510404_inc_T31
Value
<2x
NCT02510404_inc_T32
Measurement
AST
NCT02510404_inc_T33
Value
<3x
NCT02510404_inc_T34
Measurement
Serum creatinine
NCT02510404_inc_T35
Value
<2x upper limit of normal
NCT02510404_inc_T36
Measurement
Hgb
NCT02510404_inc_T37
Value
>8.0
NCT02510404_inc_T38
Measurement
Pulse oximetry on room air
NCT02510404_inc_T39
Value
> 90%
NCT02510404_inc_T40
Measurement
pregnancy test
NCT02510404_inc_T41
Value
Negative
NCT02510404_inc_T42
Condition
childbearing potential
NCT02510404_inc_T43
Person
female
NCT02510404_inc_T44
Scope
female of childbearing potential