Patients with systolic blood pressure <100 mmHg or basal heart rate <60/min
Portal vein thrombosis
Uncontrolled ascites or hepatic encephalopathy
Severe coagulation disorder: prothrombin time <40% (or INR >1.7) or platelet count <30,000/mm3
Medium or large sized gastric or duodenal varices
Coexisting malignancy
Severe cardiovascular disorder, renal failure, peritonitis, sepsis
Severe erosive esophagitis, severe esophageal stricture, active gastric or duodenal ulcer
Contraindication to beta-blocker
Pregnancy
Refusal to give consent to participate in the trial

NCT00965900_exc_T1
Measurement
systolic blood pressure
NCT00965900_exc_T2
Value
<100 mmHg
NCT00965900_exc_T3
Measurement
heart rate
NCT00965900_exc_T4
Qualifier
basal
NCT00965900_exc_T5
Value
<60/min
NCT00965900_exc_T6
Condition
Portal vein thrombosis
NCT00965900_exc_T7
Condition
ascites
NCT00965900_exc_T8
Condition
hepatic encephalopathy
NCT00965900_exc_T9
Qualifier
Uncontrolled
NCT00965900_exc_T10
Condition
coagulation disorder
NCT00965900_exc_T11
Qualifier
Severe
NCT00965900_exc_T12
Measurement
prothrombin time
NCT00965900_exc_T13
Value
<40%
NCT00965900_exc_T14
Measurement
INR
NCT00965900_exc_T15
Value
>1.7
NCT00965900_exc_T16
Measurement
platelet count
NCT00965900_exc_T17
Value
<30,000/mm3
NCT00965900_exc_T18
Scope
prothrombin time <40% (or INR >1.7) or platelet count <30,000/mm3
NCT00965900_exc_T19
Condition
duodenal varices
NCT00965900_exc_T20
Condition
ric or C
NCT00965900_exc_T21
Qualifier
large
NCT00965900_exc_T22
Qualifier
Medium
NCT00965900_exc_T23
Scope
gastric or duodenal varices
NCT00965900_exc_T24
Scope
Medium or large
NCT00965900_exc_T25
Condition
malignancy
NCT00965900_exc_T26
Qualifier
Coexisting
NCT00965900_exc_T27
Condition
cardiovascular disorder
NCT00965900_exc_T28
Qualifier
Severe
NCT00965900_exc_T29
Condition
renal failure
NCT00965900_exc_T30
Condition
peritonitis
NCT00965900_exc_T31
Condition
sepsis
NCT00965900_exc_T32
Condition
erosive esophagitis
NCT00965900_exc_T33
Condition
esophageal stricture
NCT00965900_exc_T34
Condition
duodenal ulcer
NCT00965900_exc_T35
Condition
 or du ontra
NCT00965900_exc_T36
Qualifier
active
NCT00965900_exc_T37
Qualifier
severe
NCT00965900_exc_T38
Qualifier
Severe
NCT00965900_exc_T39
Scope
gastric or duodenal ulcer
NCT00965900_exc_T40
Condition
Contraindication
NCT00965900_exc_T41
Drug
beta-blocker
NCT00965900_exc_T42
Condition
Pregnancy