Subjects with a supine BP >140 mm Hg systolic or >90 mm Hg diastolic or <100 mm Hg systolic or <60 mm Hg diastolic based on the average of the triplicate 
Serum potassium >=5.1 mmol/L or <3.5 mmol/L at screening, confirmed by a single repeat if deemed necessary. 
Estimated GFR <60 mL/min/1.73 m2 using the Cockcroft-Gault formula measurement of the individual parameters following at least 5 minutes of rest at Screening.       
    

NCT01314898_exc_T1
Measurement
supine BP
NCT01314898_exc_T2
Value
>140 mm Hg systolic
NCT01314898_exc_T3
Value
>90 mm Hg diastolic
NCT01314898_exc_T4
Value
<100 mm Hg systolic
NCT01314898_exc_T5
Value
<60 mm Hg diastolic
NCT01314898_exc_T6
Scope
>140 mm Hg systolic or >90 mm Hg diastolic or <100 mm Hg systolic or <60 mm Hg diastolic
NCT01314898_exc_T7
Measurement
Serum potassium
NCT01314898_exc_T8
Value
>=5.1 mmol/L
NCT01314898_exc_T9
Value
<3.5 mmol/L
NCT01314898_exc_T10
Temporal
at screening
NCT01314898_exc_T11
Scope
>=5.1 mmol/L or <3.5 mmol/L
NCT01314898_exc_T12
Measurement
Estimated GFR
NCT01314898_exc_T13
Value
<60 mL/min/1.73 m2
NCT01314898_exc_T14
Observation
Cockcroft-Gault formula