Preoperative renal failure requiring dialysis
Poorly controlled pulmonary disease (severe asthma or COPD) -Contraindication to regional anesthesia (recent anticoagulant use)
Sleep apnea or morbid obesity with possible sleep apnea
Allergy to methadone
Significant preoperative pain requiring treatment with high doses of opioids (more than 6-8 Norco tablets or equivalence per day) or recent history of opioid abuse

NCT03084588_exc_T1
Temporal
Preoperative
NCT03084588_exc_T2
Condition
renal failure
NCT03084588_exc_T3
Mood
requiring
NCT03084588_exc_T4
Procedure
dialysis
NCT03084588_exc_T5
Qualifier
Poorly controlled
NCT03084588_exc_T6
Condition
pulmonary disease
NCT03084588_exc_T7
Qualifier
severe
NCT03084588_exc_T8
Condition
asthma
NCT03084588_exc_T9
Condition
COPD
NCT03084588_exc_T10
Scope
asthma or COPD
NCT03084588_exc_T11
Scope
severe asthma or COPD
NCT03084588_exc_T12
Condition
Contraindication
NCT03084588_exc_T13
Procedure
regional anesthesia
NCT03084588_exc_T14
Temporal
recent
NCT03084588_exc_T15
Drug
anticoagulant
NCT03084588_exc_T16
Scope
Contraindication to regional anesthesia
NCT03084588_exc_T17
Scope
recent anticoagulant
NCT03084588_exc_T18
Condition
Sleep apnea
NCT03084588_exc_T19
Condition
morbid obesity
NCT03084588_exc_T20
Mood
possible
NCT03084588_exc_T21
Condition
sleep apnea
NCT03084588_exc_T22
Condition
Allergy
NCT03084588_exc_T23
Drug
methadone
NCT03084588_exc_T24
Condition
preoperative pain
NCT03084588_exc_T25
Qualifier
Significant
NCT03084588_exc_T26
Mood
requiring
NCT03084588_exc_T27
Multiplier
high doses
NCT03084588_exc_T28
Drug
opioids
NCT03084588_exc_T29
Multiplier
 than 6-8 No day) or
NCT03084588_exc_T30
Drug
Norco tablets
NCT03084588_exc_T31
Drug
equivalence
NCT03084588_exc_T32
Temporal
recent
NCT03084588_exc_T33
Observation
history
NCT03084588_exc_T34
Condition
opioid abuse
NCT03084588_exc_T35
Scope
more than 6-8 Norco tablets or equivalence per day