History of active rheumatic diseases
History of previous musculoskeletal injury of the same knee for excluding patients with secondary knee osteoarthritis
History of previous surgery on the same knee
History of adverse effects from medications to be used in this study
Contraindication to spinal anesthesia
History of psychiatric disorders or cognitive impairment
Contraindication to corticosteroid agents
Poorly controlled diabetes mellitus (HbA1C > 7.5)
Poorly controlled hypertension
History of ischemic heart disease or peripheral arterial disease or cerebrovascular disease
Hepatic insufficiency (Child-Pugh score > 5)
Renal insufficiency (Creatinine clearance < 30 mL/min)
History of cataracts or glaucoma or ocular hypertension
History of steroid or immunosuppressive drug use within 6 months of surgery

NCT02760459_exc_T1
Condition
rheumatic diseases
NCT02760459_exc_T2
Qualifier
active
NCT02760459_exc_T3
Condition
musculoskeletal injury
NCT02760459_exc_T4
Qualifier
knee
NCT02760459_exc_T5
Condition
secondary knee osteoarthritis
NCT02760459_exc_T6
Procedure
surgery
NCT02760459_exc_T7
Qualifier
knee
NCT02760459_exc_T9
Condition
Contraindication
NCT02760459_exc_T10
Procedure
spinal anesthesia
NCT02760459_exc_T11
Condition
psychiatric disorders
NCT02760459_exc_T12
Condition
cognitive impairment
NCT02760459_exc_T13
Condition
Contraindication
NCT02760459_exc_T14
Drug
corticosteroid
NCT02760459_exc_T15
Condition
diabetes mellitus
NCT02760459_exc_T16
Qualifier
Poorly controlled
NCT02760459_exc_T17
Measurement
HbA1C
NCT02760459_exc_T18
Value
> 7.5
NCT02760459_exc_T19
Qualifier
Poorly controlled
NCT02760459_exc_T20
Condition
hypertension
NCT02760459_exc_T21
Condition
ischemic heart disease
NCT02760459_exc_T22
Condition
peripheral arterial disease
NCT02760459_exc_T23
Condition
cerebrovascular disease
NCT02760459_exc_T24
Condition
Hepatic insufficiency
NCT02760459_exc_T25
Measurement
Child-Pugh score
NCT02760459_exc_T26
Value
> 5
NCT02760459_exc_T27
Condition
Renal insufficiency
NCT02760459_exc_T28
Measurement
Creatinine clearance
NCT02760459_exc_T29
Value
< 30 mL/min
NCT02760459_exc_T30
Condition
cataracts
NCT02760459_exc_T31
Condition
glaucoma
NCT02760459_exc_T32
Condition
ocular hypertension
NCT02760459_exc_T33
Drug
steroid
NCT02760459_exc_T34
Drug
immunosuppressive drug
NCT02760459_exc_T35
Temporal
within 6 months of surgery
NCT02760459_exc_T36
Reference_point
surgery
NCT02760459_exc_T37
Scope
steroid or immunosuppressive drug