With acute diseases, such as acute phase after myocardial infarction (within 3 months), within 3 months after acute heart failure or new cerebral infarction;
In the list of heart transplantation;
Expected survival less than 1 year;
With other hemorrhagic diseases and anticoagulant therapy is not allowed;
Thrombosis in left atrium;
Heart failure, New York Heart Association(NYHA) III/IV or eject fraction(EF)<40%;
Patients with uncontrolled cancer;
Significant hepatic or renal impairment (and/or alanine transaminase(ALT) or Aspartate transaminase(AST) >2 times upper limit of normal, creatinine clearance rate(CCr)<50%);
Previous catheter radiofrequency ablation for AF or cardiac surgery;
Pregnant and lactating women, women who plan to become pregnant, or women of child bearing age not using reliable contraceptive measures.

NCT02637453_exc_T1
Condition
acute diseases
NCT02637453_exc_T2
Temporal
acute phase
NCT02637453_exc_T3
Condition
myocardial infarction
NCT02637453_exc_T4
Temporal
within 3 months
NCT02637453_exc_T5
Temporal
within 3 months
NCT02637453_exc_T6
Condition
acute heart failure
NCT02637453_exc_T7
Condition
cerebral infarction
NCT02637453_exc_T8
Scope
acute heart failure or new cerebral infarction
NCT02637453_exc_T9
Scope
acute phase after myocardial infarction (within 3 months), within 3 months after acute heart failure or new cerebral infarction
NCT02637453_exc_T10
Procedure
heart transplantation
NCT02637453_exc_T11
Mood
In the list
NCT02637453_exc_T12
Observation
Expected survival
NCT02637453_exc_T13
Value
less than 1 year
NCT02637453_exc_T14
Condition
hemorrhagic diseases
NCT02637453_exc_T15
Qualifier
other
NCT02637453_exc_T16
Procedure
anticoagulant therapy
NCT02637453_exc_T17
Condition
not allowed
NCT02637453_exc_T18
Condition
Thrombosis
NCT02637453_exc_T19
Qualifier
left atrium
NCT02637453_exc_T20
Condition
Heart failure
NCT02637453_exc_T21
Measurement
New York Heart Association(NYHA)
NCT02637453_exc_T22
Value
III/IV
NCT02637453_exc_T23
Measurement
eject fraction(EF)
NCT02637453_exc_T24
Value
<40%
NCT02637453_exc_T25
Qualifier
uncontrolled
NCT02637453_exc_T26
Condition
cancer
NCT02637453_exc_T27
Condition
renal impairment
NCT02637453_exc_T28
Condition
 or re ent (and/o
NCT02637453_exc_T29
Qualifier
Significant
NCT02637453_exc_T30
Scope
hepatic or renal impairment
NCT02637453_exc_T31
Measurement
alanine transaminase(ALT)
NCT02637453_exc_T32
Measurement
Aspartate transaminase(AST)
NCT02637453_exc_T33
Value
>2 times upper limit of normal
NCT02637453_exc_T34
Measurement
creatinine clearance rate(CCr)
NCT02637453_exc_T35
Value
<50%
NCT02637453_exc_T36
Scope
alanine transaminase(ALT) or Aspartate transaminase(AST) >2 times upper limit of normal, creatinine clearance rate(CCr)<50%
NCT02637453_exc_T37
Procedure
catheter radiofrequency ablation
NCT02637453_exc_T38
Condition
AF
NCT02637453_exc_T39
Procedure
cardiac surgery