Anticoagulant prophylaxis markedly reduces @entity1031 in XXXX .

@entity1 @entity49 @entity699 @entity1031 @entity4461 @entity701 @entity2880 @entity1229
@entity49 state and an increased incidence of @entity1031 are reported in @entity699 . The @entity49 state is related to an increase in plasma clotting factors, especially Factor VIII and @entity2880 factor complex, and to an impairment of fibrinolytic capacity. Retrospective analysis of postoperative @entity1031 in a large group of @entity1 with @entity699 , including 75 @entity1 (group 1) evaluated in the period from 1972-1981 not receiving anticoagulants, and 232 @entity1 (group 2), evaluated in the period from 1982-2000. @entity1 of group 1 underwent routine hemostatic function, i.e. prothrombin time and activated partial thromboplastine time. @entity1 of group 2 underwent a thorough investigation as to hemostatic parameters and received prophylactic treatment with heparin and/or @entity1229 . @entity1 with @entity699 showed @entity4461 . A significant correlation between activated partial thromboplastine time and urinary free @entity701 was observed. During follow-up, 15 @entity1 (20%; mean follow-up, 9.4 +/- 6.4 yr) of group 1 and 14 (6.0%; mean follow-up, 6.6 +/- 4.2 yr) of group 2 showed @entity1031 . Of these @entity1 , eight of group 1 and one of group 2 died. Survival analysis demonstrated a significantly higher morbidity and mortality due to @entity1031 in group 1, not receiving anticoagulant prevention, than in group 2, treated with anticoagulants in the perioperative period until cure of the disease and normalization of clotting parameters. @entity699 is associated with a @entity49 state. An adequate anticoagulant prophylaxis can reverse this prothrombotic state and avoid postoperative @entity1031 .
