Bone mineral density in premenopausal XXXX with @entity1252 .

@entity1 @entity170 @entity228 @entity1252 @entity79 @entity460 @entity288
OBJECTIVE: To study @entity79 ( @entity79 ) in premenopausal @entity1 with @entity1252 ( @entity1252 ) and to evaluate the influence of disease activity and use of corticosteroids. METHODS: A cross-sectional study on @entity79 of 118 premenopausal @entity1 with @entity1252 . @entity1 were divided into 2 groups, 74 who had been treated with @entity288 and 44 who had not. @entity79 at lumbar spine, femoral neck, and trochanter was measured. RESULTS: @entity79 in @entity1 without and with @entity228 treatment was 1.13 +/- 0.13 vs 1.05 +/- 0.14 g/cm2 (p = 0.005) at lumbar spine, 0.92 +/- 0.12 vs 0.86 +/- 0.12 g/cm2 (p = 0.005) at femoral neck, and 0.78 +/- 0.13 vs 0.72 +/- 0.12 g/cm2 (p = 0.014) at trochanter, respectively. Stepwise multilinear regression analysis showed that corticosteroid exposure was independently associated with decreased @entity79 in the corticosteroid treated @entity1 (r2 = 7% for lumbar and 6.6% for trochanter model). No significant difference in @entity79 in corticosteroid treated @entity1 appeared when they were subgrouped according to whether they were taking @entity460 supplements. Prevalence of @entity170 at lumbar spine in corticosteroid treated @entity1 was 1.4%, and was lower than reported for age and sex matched Caucasians. CONCLUSION: @entity79 measurements were significantly lower in premenopausal @entity1252 @entity1 who had had corticosteroid treatment than those who had not. There was a negative correlation between @entity79 and corticosteroid therapy, but not disease activity. Prevalence of @entity170 , based on lumbar spine @entity79 , was lower than that reported in Caucasians.
