Primary XXXX of the parotid gland.

@entity1 @entity1893 @entity792 @entity706
OBJECTIVES: To document the clinicopathologic features of primary @entity706 of the parotid gland based on analysis of our cases and to compare the results with similar studies in the literature. DESIGN: Retrospective, nonrandomized case study. SETTING: Academic, tertiary medical center. @entity1 : Forty-one consecutive cases of @entity706 of the parotid gland were identified among 820 @entity1 who had undergone parotid surgery during the course of 22 years. Thirty-three (80%) of these were @entity706 and were included in the study. Eight (20%) occurred in @entity1 with a history of @entity706 and were therefore excluded. INTERVENTION: Diagnosis was established by open parotid biopsy in 8 @entity1 , superficial lobectomy in 23, and total parotidectomy in 2. After diagnosis, @entity706 were staged and treated with local irradiation and/or chemotherapy. RESULTS: Fifteen @entity1 and 18 @entity1 aged 26 to 100 years (mean, 66 years) had an enlarging painless mass on initial examination. Seven (21%) had an underlying @entity792 and 20 (61%) had Ann Arbor stage 1 disease at diagnosis. Of 25 @entity1 available for a minimum 2-year follow-up, 16 (64%) were alive with or without disease. Histological grade was the only prognostic feature associated with outcome (P<.01). CONCLUSIONS: Our study, when viewed collectively with those in the literature, indicates that @entity706 of the parotid gland are uncommon and often not suspected clinically. The disease affects both sexes equally and is unusual before the age of 50 years. Most are B-cell, @entity1893 , and about 80% of @entity1 have Ann Arbor stage I or II disease at diagnosis.
