@entity194 and lower regional perfusion of temporo-parietal brain areas are correlated with @entity2414 and increase of EEG upper alpha power in prodromal XXXX .

@entity73 @entity2414 @entity194 @entity195
BACKGROUND: Temporo-parietal cortex thinning is associated with @entity73 ( @entity73 ) due to @entity195 ( @entity195 ). The increase of the EEG upper/low alpha power ratio has been associated with @entity73 due to @entity195 subjects and to the @entity194 of temporo-parietal brain areas. Moreover, subjects with a higher alpha3/alpha2 frequency power ratio showed lower brain perfusion than in the low alpha3/alpha2 group. The two groups have significantly different hippocampal volumes and correlation with the theta frequency activity. METHODS: 74 adult subjects with @entity73 underwent clinical and neuropsychological evaluation, electroencephalogram (EEG) recording, and high resolution 3D magnetic resonance imaging (MRI). 27 of them underwent EEG recording and perfusion single-photon emission computed tomography (SPECT) evaluation. The alpha3/alpha2 power ratio as well as cortical thickness was computed for each subject. The difference in cortical thickness between the groups was estimated. Pearson's r was used to assess the correlation topography between cortical thinning as well as between brain perfusion and @entity2414 . RESULTS: In the higher upper/low alpha group, @entity2414 was more pronounced both in the MRI group and the SPECT @entity73 group. Moreover, it was correlated with greater cortical @entity194 and lower perfusional rate in temporo-parietal cortex. CONCLUSION: High EEG upper/low alpha power ratio was associated with cortical thinning lower perfusion in temporo-parietal. Moreover, @entity194 and lower perfusional rate were both significantly correlated with @entity2414 in @entity73 subjects. The increase of EEG upper/low alpha frequency power ratio could be useful for identifying individuals at risk for progression to @entity195 and may be of value in the clinical context.
