Comparison between cell kinetical and immunohistochemical studies on XXXX and atypia/dysplasia of urinary bladder mucosa.

@entity865 @entity189 @entity2735 @entity787
Results of cell kinetic analyses on transurethrally obtained material from urinary bladder are compared with parallel immunohistochemical tests on @entity787 ( @entity787 ) and tissue polypeptide antigen ( @entity865 ), performed on the same material. Labelling index increases from 1.4% in slight to 20% in marked urothelial atypia. @entity787 reaction in slight atypia is slight or moderate, slight, moderate or distinct in atypia, and moderate to distinct in @entity2735 . @entity865 always shows moderate to distinct reactions. Cell kinetically, @entity189 yield similar gradations. They were positive for @entity787 in 70% and for @entity865 in 100%. In @entity189 , negative and slightly positive reactions predominate, poorly differentiated lesions yield predominantly distinct reactions. In all grades, @entity865 ranges from slight to distinctly positive. As in cell kinetic analyses, there is a relationship between differentiation grade and stage for @entity787 expression. This does not apply for @entity865 . The results permit us to draw conclusions on the different biological and histogenetical behavior of @entity189 . There are undoubtedly differences in the behavior of papillary-exophytical and solid @entity189 in terms of both cell kinetics and immunohistochemistry.
