Comparing mortality of @entity242 , XXXX , and @entity420 in the surveillance, epidemiology, and end results database.

@entity1 @entity242 @entity146 @entity5 @entity957 @entity1544 @entity3 @entity420
OBJECTIVE: To evaluate the mortality outcomes of @entity242 in a large cohort compared with @entity1544 . METHODS: @entity1 with primary invasive @entity242 , @entity957 , and @entity420 diagnosed between 1988 and 2010 were identified within the National @entity5 Institute's Surveillance, Epidemiology, and End Results database. Parametric and nonparametric methods were used to compare the demographic and clinical characteristics of @entity1 among the three @entity5 types as well as between @entity242 histologic subtypes. Overall and @entity5 -specific mortality outcomes were examined using Kaplan-Meier and multivariable Cox proportional hazards models. RESULTS: The final cohort consisted of 3,121 @entity1 with @entity957 , 720 @entity1 with @entity420 , and 221 @entity1 with @entity242 . Compared with @entity1 with @entity957 and @entity420 , @entity1 diagnosed with @entity242 tended to be younger, have @entity5 with less regional extension and lymph node positivity, and be treated primarily with surgery without radiation. In unadjusted analysis, 5-year mortality rates border 30% for all three histologies. After adjusting for other prognostic factors including use of radiation and surgery, @entity1 with @entity242 had a 69% greater risk of @entity5 -related mortality compared with @entity1 with @entity957 (hazard ratio 1.69, 95% confidence interval 1.26-2.26). Although @entity242 histology failed to associate with mortality risk, age, @entity5 extension and @entity3 , and surgery were poor prognostic factors. CONCLUSION: Primary @entity242 are @entity146 with different presenting characteristics and increased adjusted risk of mortality compared with squamous cell and @entity420 subtypes. LEVEL OF EVIDENCE: III.
