Soft-tissue @entity242 of the XXXX : surgical treatment and outcome.

@entity1 @entity242 @entity2045 @entity5 @entity3
The objective of this retrospective follow-up study was to evaluate the outcome of @entity1 with soft-tissue @entity242 treated by the authors' protocol, which consists of a selective combination of conservative surgery and radiotherapy. @entity1 who relapsed were especially evaluated to improve treatment results. The authors examined 80 @entity1 with local soft-tissue @entity242 in the @entity2045 referred to their multidisciplinary group. Fifteen @entity1 were referred for first or subsequent local recurrence, and 65 @entity1 were treated for @entity5 . The goal of treatment was local control and preservation of a functional limb. Wide excision was attempted. If the margin was less than 2.5 cm, postoperative radiotherapy was administered. Eighty-five percent of the @entity1 were treated by limb salvage. Thirty @entity1 needed reconstructive procedures such as pedicled (20 @entity1 ) or free flaps (10 @entity1 ). No free flaps were lost. The 5-year disease-specific overall survival rate was 75 percent, the local recurrence-free survival rate was 79 percent, and the metastasis-free survival rate was 68 percent. In univariate analysis, prognostic factors for local recurrence were extracompartmental site; for development of @entity3 , large size and extracompartmental site; and for decreased disease-specific overall survival, large size and extracompartmental site. Intramuscular, cutaneous, and @entity5 had a 5-year local control rate of 100 percent, and extracompartmental @entity5 had a local control rate of 69 percent. Extracompartmental @entity5 clearly have the worst prognosis and should be the main target for improving treatment strategies. After exclusion of @entity1 with inadequate treatment according to the authors' protocol, the local control rate at 5 years was 90 percent. Strict adherence to treatment protocol should be practiced.
