Deep anterior lamellar keratoplasty of XXXX eyes using the big-bubble technique.

@entity235 @entity4 @entity267 @entity195
This study was conducted to establish the feasibility of corneal transplantation using the big-bubble technique (BBT) to perform deep anterior lamellar keratoplasty (DALK) in three @entity235 . After the @entity267 was trephined 750   m, 4 mL of air was injected, and the blanched stroma was removed to expose @entity195 ( @entity195 ). The donor corneal button, which was gently stripped off the @entity195 , was sutured onto the bare @entity195 of the recipient @entity267 . The @entity235 received topical antibiotics every 6 h for 7 days and 2% cyclosporine ointment every 12 h for 1 month. The eyes were examined post-operatively at 7, 14, 21, 28 and 150 days. The central portion of the transplanted @entity267 stayed transparent while corneal haze developed around the transplanted margin. Menace response was normal even though the transplanted @entity267 was @entity4 until 3 weeks after surgery. A marginal haze was rarely observed between the donor and recipient corneas at 150 days after the operation. A spotted haze developed in the central part of the deep stroma near the @entity195 . Upon histopathological examination, the stroma and epithelium of the donor @entity267 had normal structures. Corneal transplantation using DALK with BBT can be performed in @entity235 preserving the healthy endothelium.
