XXXX -induced cardiomyopathy: a reversible form of @entity1002 .

@entity1 @entity591 @entity299 @entity943 @entity1002
Eight @entity1 , aged 5 to 57 years, with uncontrolled symptomatic @entity591 for 2.5 to 41 years (mean 15) and significant @entity1002 in the absence of any other apparent underlying @entity299 underwent evaluation. Incessant @entity591 was present for 0.5 to 6.0 years (mean 2.1) in 7 @entity1 . One @entity1 had an ectopic @entity591 and 7 @entity1 had an accessory atrioventricular pathway that participated in reciprocating @entity591 . Six @entity1 underwent surgery; the ectopic focus was ablated in 1 @entity1 and an accessory pathway was divided in 5 @entity1 . One @entity1 underwent open ablation of the His bundle and 1 @entity1 underwent closed-chest ablation of the atrioventricular conduction system. Myocardial biopsy specimens were obtained from 5 @entity1 , none of which yielded a specific diagnosis. Pretreatment radionuclide angiography demonstrated a mean ejection fraction (EF) of 19 +/- 9% (range 10 to 35%). Following @entity591 control a marked improvement in LV function was noted in 6 of 8 @entity1 at rest and in 1 additional @entity1 during exercise. The EF increased to 33 +/- 17% (range 16 to 56%) an average of 8 days after treatment and to 45 +/- 15% (range 22 to 67%) at late follow-up 3.5 +/- 40 months (mean 17) later (p less than 0.005). Seven @entity1 remain asymptomatic 11 to 40 months (mean 22) after the corrective procedure and have resumed normal activities. These findings suggest that chronic uncontrolled @entity591 may result in significant @entity1002 , which is reversible in some cases after control of the @entity943 .
