Detection of @entity5 -specific antigens in XXXX .

@entity2008 @entity1861 @entity981 @entity5 @entity12297 @entity1860
In @entity1860 ( @entity1860 ) and @entity981 ( @entity981 ) the @entity12297 chromosome (22q-) is the most frequent @entity2008 encountered. At the molecular level the @entity1861 gene from chr. 9 is translocated to the bcr gene on chr. 22. As a result, a chimeric @entity1861 gene is generated, which encodes chimeric proteins. Since these proteins are only expressed in @entity12297 positive cells, they are per definition @entity5 -specific. In this report we describe the reactivity of polyvalent antisera raised against synthetic peptides corresponding to the @entity5 -specific @entity1861 junctions. Native chimeric proteins were specifically recognized by these junction-specific antisera. Therefore we conclude that the @entity1861 junctions are antigenically exposed on the chimeric proteins. We discuss the relevance of these antisera for @entity1860 and @entity981 diagnosis.
