Prevalence and predictors of treatment dropout from physical activity interventions in XXXX : a meta-analysis.

@entity1 @entity161 @entity65 @entity146
OBJECTIVE: Physical activity interventions have been shown to improve the health of @entity1 with @entity161 , yet treatment dropout poses an important challenge in this population, and rates vary substantially across studies. We conducted a meta-analysis to investigate the prevalence and predictors of treatment dropout in physical activity interventions in @entity1 with @entity161 . METHOD: We systematically searched major electronic databases from inception until August 2015. Randomized controlled trials of physical activity interventions in @entity1 with @entity161 reporting dropout rates were included. Two independent authors conducted searches and extracted data. Random-effects meta-analysis and meta-regression analyses were conducted. RESULTS: In 19 studies, 594 @entity1 with @entity161 assigned to exercise interventions were investigated (age=37.2 years, 67.5% male, range=37.5%-100%). Trim and fill adjusted treatment dropout rate was 26.7% [95% confidence interval (CI)=19.7%-35.0%], which is more than double than in nonactive control interventions (odds ratio=2.15, 95% CI=1.29-3.58, P=.003). In the multivariate regression, qualification of the professional delivering the intervention (b=-1.06, 95% CI=-1.77 to -0.35, P=.003) moderated treatment dropout rates, while continuous supervision of physical activity approached statistical significance (P=.05). CONCLUSIONS: Qualified professionals (e.g., physical therapists/exercise physiologists) should prescribe supervised physical activity for @entity1 with @entity161 to enhance adherence, improve @entity146 symptoms and reduce the onset and burden of @entity65 .
