XXXX : report of seven cases.

@entity1 @entity3852 @entity5 @entity1489 @entity3 @entity34
@entity3852 ( @entity3852 ) is an infrequent, highly malignant, primary @entity1489 derived from neuroendocrine cells. Most MCCs occur in elderly individuals, on sun-exposed areas of the body, with the head and neck being the most common sites. We present 7 @entity1 (2 male and 5 female, age 45-80 years) suffering from @entity3852 and treated between 1993 and 2000. All @entity5 were located on the head and neck and varied from 0.9 to 2.3 cm in size. Five of the @entity1 had @entity34 , 1 @entity1 had stage Ia disease and 1 @entity1 had @entity5 . Six of the @entity1 had positive regional lymph nodes. All @entity1 had local excision of the @entity5 . Six of them also had lymph node dissection and in 5 of them a superficial parotidectomy was performed. Five @entity1 received adjuvant radiotherapy and 3 of them also received chemotherapy. Local and cervical lymph node recurrence was observed in only 1 @entity1 . @entity3 occurred in 5 @entity1 . One @entity1 died within 10 days for other reasons. The @entity1 with the @entity5 had a survival of 7 months. The other 5 @entity1 had survivals varying from 15 to 54 months. @entity3852 is a @entity1489 with very poor prognosis and high recurrence and metastatic rates. Its treatment is still under discussion. Radical excision of the @entity5 is the main method of treatment. Selective lymph node dissection is suggested. Superficial parotidectomy seems necessary, especially if the @entity5 is on the auricle. Adjuvant radio- and chemotherapy may extend survival in case of @entity5 .
