Case report: severe central nervous system involvement in XXXX .

@entity1 @entity227 @entity455 @entity1910 @entity1333 @entity425 @entity3173 @entity8817 @entity1011
We present 3 @entity1 with @entity8817 ( @entity8817 ) and severe central nervous system (CNS) complications. All @entity1 had at least 4 positive criteria of Bohan and Peter, which confirmed a definite diagnosis of @entity8817 . They were all male, and had a relatively high @entity1011 kinase value at admission (1532-4260 U/l). Besides, progressive proximal @entity425 and @entity1910 , one @entity1 presented with rapid irreversible @entity227 . Ophthalmologic examination showed active @entity1333 . After 2 weeks of treatment with immunosuppressive drugs and being in improved, relatively stable clinical condition, all 3 @entity1 developed generalized @entity3173 . Other causes of the neurological symptoms could be excluded. In all 3 @entity1 , the course of @entity8817 was fatal. The clinical symptoms and further investigations in our @entity1 show CNS involvement in @entity8817 . Although rarely reported, CNS @entity455 can be a serious and life-threatening complication of @entity8817 .
