The hypocholesterolemic and antioxidative effect of dietary @entity12873 and @entity33359 supplementation on high- @entity165 fed XXXX .

@entity12873 @entity57862 @entity33359 @entity5872 @entity224 @entity165
The current study investigated the effect of natural @entity12873 extracted from fenugreek seeds, in comparison with the pure standard @entity12873 , plus @entity33359 ( @entity57862 ) supplementation on high- @entity165 fed @entity5872 . Quails were randomly divided into four groups. Group one (n = 25) fed experimental diet only (control; contained basal diet supplemented with 1% @entity165 ), group 2 (n = 20) fed experimental diet supplemented with @entity57862 only (400 microg kg(-1) of body weight), groups 3 and 4 (n = 30 per group) were fed experimental diet supplemented with either 0.5% (w/w) of extracted @entity12873 plus @entity57862 or pure standard @entity12873 (0.5%) plus @entity57862 respectively, for 12 days. Blood samples were collected at days 0 and 12 for measuring levels of lipid profile. The work was carried out at Applied Science University and Amman University, Amman, Jordan during the period from October 2009 through October 2010. The mean levels of total @entity165 (TC) in control quails at d12 was significantly (p < 0.01) increased compare to those at d0. Supplementation of diet with @entity57862 alone or @entity57862 with @entity12873 either extracted or pure standard for 12 days showed a significant (p < 0.01) decrease in TC and low density lipoprotein @entity165 (LDL-C) levels as compared to those in the control quails. While, high density lipoprotein @entity165 (HDL-C) increased significantly (p < 0.01) in quails supplemented with @entity12873 and @entity57862 . At d12, the mean @entity224 Dismutase (SOD) activities in erythrocytes of quails in all supplemented groups was significantly (p < 0.01) increased as compared to those in control group and was more pronounced in erythrocytes of quails supplemented with pure standard @entity12873 plus @entity57862 . These results indicated that the combined @entity12873 and @entity57862 supplementation to high- @entity165 fed quails might induce a protective effect by both regulating lipid and antioxidative damage.
