XXXX in adults with single ventricle physiology after cavopulmonary palliation.

@entity1 @entity26 @entity358 @entity299 @entity1211
OBJECTIVES: To assess the frequency, anatomic characteristics, and associations of @entity358 in adult @entity1 undergoing cardiac catheterization after a Fontan operation. Additionally, the embryologic basis for the presence of venous collaterals is reviewed. METHODS: Cardiac catheterization data was reviewed for 66 adults with single ventricle physiology and a Fontan palliation. RESULTS: There were a total of 66 @entity1 that underwent catheterization between 2004 and 2014 at the Ahmanson/UCLA Adult @entity299 Center. There were 24 males and 42 females. @entity1211 were present in 38 @entity1 (58%), most commonly originating from the right brachiocephalic vein (35%), azygous vein (20%) and superior vena cava (13%). Trans-catheter interventional closure was performed in 27/38 (71%) of @entity1 with venous collaterals. At baseline these @entity1 had lower @entity26 saturation when compared to those not requiring intervention, 85.6%  6.1% vs 89.9%  5.4%, p<0.05. At 6months, the ambulatory systemic saturation improved from 85.6%  6.1% to 91.8%  6.4%, p<0.05. At two years follow-up, the ambulatory systemic saturation had decreased to 90.5%  4.1% (p<0.05). CONCLUSION: In adults with single ventricle physiology and prior Fontan surgery, systemic venous collaterals are common and can be percutaneously occluded at minimal risk with resultant improvement in systemic @entity26 saturation on long term follow up. When evaluated from a developmental standpoint, 85% of collaterals are above the diaphragm and could be secondary to recanalization of the collateral veins, an embryological connection between systemic and pulmonary veins.
