Normal weight @entity28 : relationship with lipids, glycaemic status, liver enzymes and XXXX .

@entity1 @entity32 @entity5428 @entity28 @entity167 @entity1254 @entity492 @entity493
BACKGROUND AND AIMS: Normal weight @entity28 (NWO) is defined as an excessive body fat associated with a normal body mass index (BMI) and has been associated with early @entity32 , but its relationship with cardiovascular risk factors await investigation. METHODS AND RESULTS: Cross-sectional study including 3213 @entity1 and 2912 @entity1 aged 35-75 years to assess the clinical characteristics of NWO in Lausanne, Switzerland. Body fat was assessed by bioimpedance. NWO was defined as a BMI<25 kg/m(2) and a % body fat >= 66(th) gender-specific percentiles. The prevalence of NWO was 5.4% in @entity1 and less than 3% in @entity1 , so the analysis was restricted to @entity1 . NWO @entity1 had a higher % of body fat than overweight @entity1 . After adjusting for age, smoking, educational level, physical activity and @entity167 consumption, NWO @entity1 had higher blood pressure and lipid levels and a higher prevalence of dyslipidaemia (odds-ratio=1.90 [1.34-2.68]) and fasting hyperglycaemia (odds-ratio=1.63 [1.10-2.42]) than lean @entity1 , whereas no differences were found between NWO and overweight @entity1 . Conversely, no differences were found between NWO and lean @entity1 regarding levels of CRP, @entity1254 and liver markers ( @entity493 aminotransferase, @entity492 aminotransferase and @entity5428 transferase). Using other definitions of NWO led to similar conclusions, albeit some differences were no longer significant. CONCLUSION: NWO is almost nonexistent in @entity1 . @entity1 with NWO present with higher cardiovascular risk factors than lean @entity1 , while no differences were found for liver or inflammatory markers. Specific screening of NWO might be necessary in order to implement cardiovascular prevention.
