Safety of Proctocolectomy for XXXX Under Elective and Non-Elective Circumstances: Preoperative Corticosteroid Treatment Worsens Outcome.

@entity1 @entity73 @entity31 @entity260 @entity281 @entity6783
BACKGROUND/AIMS: Approximately 20% of @entity1 undergoing surgery for @entity31 will retain their rectum. A single-stage proctocolectomy could be an appropriate procedure in @entity1 who are definitely not candidates for a later restorative procedure, but it is generally not advised in acutely ill @entity1 . The aim was to investigate the safety of one-stage proctocolectomy under elective and non-elective circumstances, with specific reference to identifying possible risk factors for @entity260 . METHODS: A retrospective cohort study, including 54 consecutive @entity1 undergoing proctocolectomy for @entity31 . Out of these, 27 (50%) were admitted non-electively. RESULTS: @entity260 were observed in 30 @entity1 (54%). @entity6783 , wound @entity281 , and @entity73 healing were observed in 10 (18.5%), 8 (14.8%), and 10 (18.5%) of the @entity1 , respectively. There was no difference between elective and non-elective cases. Complications were observed more often in @entity1 receiving high-dose corticosteroids (18/26 vs. 12/28; p = 0.06). Impaired perineal wound healing and reoperations were observed more often in the corticosteroid-treated group (8/26 vs. 2/28; p = 0.04 and 12/26 vs. 1/28; p = 0.0003). CONCLUSIONS: Proctocolectomy is equally safe under elective and non-elective situations, but a preoperative treatment with high-dose corticosteroids is associated with an increased risk of complications and reoperations.    2015 S. Karger AG, Basel.
