Efficacy and implications of a 48-h cutoff for video capsule endoscopy application in overt obscure XXXX .

@entity1 @entity360
BACKGROUND AND STUDY AIMS: Early video capsule endoscopy (VCE) may provide a high diagnostic yield and improve clinical outcomes in @entity1 with overt obscure @entity360 (OGIB); however, there is no practical recommendation for the ideal timing of VCE application in overt OGIB. Therefore, this study investigated the diagnostic yield and efficacy of VCE to assess overt OGIB with respect to the timing of application. @entity1 AND METHODS: We retrospectively enrolled @entity1 who had undergone VCE for overt OGIB between April 2004 and February 2014at a tertiary referral academic center. We included hemodynamically stable @entity1 who underwent VCE for overt OGIB after negative bidirectional endoscopy. We analyzed the diagnostic yield of VCE, therapeutic intervention rate, and length of hospital stay. RESULTS: A total of 94 @entity1 underwent VCE to assess overt OGIB. The diagnostic yields in the groups that underwent VCE <48h and >48h from the last overt OGIB were 66.7% and 40.6%, respectively (P=0.019). Therapeutic intervention was performed in 26.7% and 9.4% of @entity1 in the <48-h and >48-h groups, respectively (P=0.028). The mean lengths of hospital stay in the <48-h and >48-h groups were 5 days (95% confidence interval [CI], 4.8-7.7) and 7 days (95%CI, 6.9-10.1), respectively (P=0.039). CONCLUSIONS: Performing VCE within 2 days from the last overt OGIB results in a higher diagnostic yield, higher therapeutic intervention rate, and shorter hospital stay. Therefore, VCE application with a 48-h cutoff could improve the outcome of @entity1 with overt OGIB.
