Relation of small artery compliance and lipoprotein (a) in XXXX with @entity731 .

@entity1 @entity407 @entity6 @entity409 @entity3452 @entity731
BACKGROUND: Lipoprotein (a) is suggested to cause @entity409 , alteration of elastic arterial properties, and decreased arterial compliance. We investigated the relation of arterial compliance and lipoprotein (a) serum [ @entity3452 ] levels in @entity1 with @entity731 . METHODS: Prospective study included 118 consecutive @entity1 with @entity731 . Noninvasive computerized pulse wave analysis was used to measure large and small artery elasticity indices in a nondiseased vessel area. Compliance parameters were correlated to @entity3452 levels. Stratified and multivariate analyses were performed to adjust for confounding factors. RESULTS: Small artery elasticity index was inversely correlated with @entity3452 serum levels (r = -0.64, P <.001). The association between @entity3452 and small artery elasticity index remained significant adjusting for age, sex, @entity6 , smoking, @entity407 , and lipid-lowering medication (r = -0.37, P <.0001). @entity3452 accounted for approximately 60% of the variation of small artery compliance in nondiabetic @entity1 (n = 80) (r = -0.76, P <.0001), in @entity6 @entity1 (n = 38) no significant correlation between @entity3452 and small artery compliance was observed (r = -0.27, P =.09). No correlation was found between large artery elasticity index and @entity3452 . CONCLUSIONS: Small artery compliance was negatively correlated to @entity3452 in nondiabetic @entity1 with @entity731 . Increased @entity3452 serum levels might cause @entity409 measurable by decreased small artery elasticity index in these @entity1 . Elastic properties of @entity6 vessels were not directly related to @entity3452 serum levels.
