Sequential fine needle aspiration biopsy in XXXX .

@entity1 @entity32 @entity8 @entity1667 @entity400 @entity631
Cellular immune mechanisms have been shown to play a prominent role in @entity631 . Cellular mediators of @entity32 cause both @entity8 . Understanding the mediation pathways offers the opportunity for therapeutic manipulation. In addition to polymorphonuclear leucocytes, monocytes/macrophages, B-cells and T-cells subsets are being enumerated in normal and diseased renal tissues. The correlation between immunological findings in peripheral blood and infiltrate composition in renal tissue, by using weekly @entity400 ( @entity400 ), for assessing the clinical status and monitoring the immunosuppressive therapy was the aim of this study. When determining the intensity of @entity32 the numerical values of the Total Corrected Increment (T.C.I.) were defined as follows: less than 1.5 no @entity32 ; from 1.5 to 2.0 @entity32 possible; greater than 2.0 @entity32 . The ratio between OKT4 and OKT8 was used as the index: greater than 2.0 immunologic activation; greater than 2.0 no immunologic activation. When the T.C.I. was greater than 1.5 and the OKT4/OKT8 less than 2.0, or the T.C.I. less than 1.5 and the OKT4/OKT8 greater than 2.0 we used only a standard treatment. When both activation indexes were in the normal range we have not treated the @entity1 . When the T.C.I. was greater than 1.5 and the OKT4/OKT8 was greater than 2.0 we treated the @entity1 with standard treatment plus @entity1667 pulses every time the activation indexes monitored by @entity400 , showed an increase. A spontaneous improvement was obtained in untreated @entity1 . The @entity1 treated by standard therapy alone showed a different outcome. All @entity1 treated with standard therapy plus @entity1667 pulses showed a progressive clinical improvement.(ABSTRACT TRUNCATED AT 250 WORDS)
