Results of surgery and irradiation or irradiation alone for XXXX .

@entity1 @entity227 @entity6726 @entity548 @entity66 @entity5 @entity699 @entity977 @entity652 @entity2014 @entity2588
A retrospective analysis was performed on the clinical course of all @entity1 with @entity977 treated at the Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University Medical Center, St. Louis, Missouri. Of 212 @entity1 treated from April 1954 through December 1982, 70 were treated with radiotherapy alone (XRT), 121 began immediate post-operative XRT (2-6 weeks) and 20 received XRT following surgical failure. Several sub-groups of @entity652 were identified and analyzed, including secreting versus non-secreting @entity652 (33.0% secreting) and by clinical syndrome; 27% with @entity2588 / @entity6726 , 18.4% acromegalic, @entity699 in 6.1% and 3.3% with @entity2014 . The median follow-up time from the data of diagnosis for those @entity1 alive at the time of last follow-up was 11.9 years (range 3.0 to 30.0 years). Actuarial overall and disease-free survival was analyzed up to 25 years. The 10-year overall and disease-free survival was 77.8 and 75.3% for those @entity1 treated with XRT alone, 86.4 and 87.2% for those treated with immediate post-operative XRT and 100.0 and 87.5% for those who were irradiated after surgical failure. Complications related directly to XRT occurred in only five @entity1 . One @entity1 had documented central nervous system radionecrosis, two had @entity227 , and @entity5 necrosis with @entity548 occurred in the other two @entity1 . In conclusion, overall survival for all @entity1 did not significantly differ from an age, sex and race matched population. Control of @entity66 was greater for those @entity1 receiving surgery and post-operative XRT than for those receiving XRT only. XRT salvage of surgical failures was possible. Treatment with XRT results in a low complication rate.
