[Childhood-onset systemic polyarteritis nodosa and XXXX : an overlap syndrome?]

@entity1 @entity1158 @entity1667 @entity64 @entity644 @entity101 @entity500 @entity1910 @entity229 @entity4 @entity1252 @entity786 @entity6383 @entity11657 @entity618 @entity850 @entity631 @entity792 @entity385
UNASSIGNED: We described herein a @entity1 who presented an overlap syndrome of @entity11657 ( @entity11657 ) and childhood-onset @entity1252 (c- @entity1252 ). A 9-year-old @entity1 presented tender subcutaneous nodules on feet, arterial @entity101 , @entity1158 and dysarthric speech. She was hospitalized due to @entity64 and left foot drop. Brain computer tomography showed @entity385 . Magnetic resonance angiography revealed @entity850 in the middle cerebral and internal carotid arteries. Electroneuromyography identified a mononeuropathy of left posterior tibial nerve and she fulfilled the @entity11657 validated criteria. She was treated with intravenous @entity1667 pulse therapy followed by @entity229 , that was progressively tapered, six months of intravenous @entity786 and after that she received @entity500 for 19 months. At the age of 14 years and 9 months, she presented @entity1910 , photosensitivity, @entity4 in lower limbs and arterial @entity101 . The @entity644 was 1.7g/day. Antinuclear antibodies (ANA) were 1/1280 (homogeneous nuclear pattern) and anti-dsDNA antibodies were positive. Renal biopsy showed focal proliferative and @entity631 . Therefore, she fulfilled the American College of Rheumatology classification criteria for @entity1252 and she was treated with @entity229 , @entity6383 and @entity618 . In conclusion, we described herein a possible overlap syndrome of two @entity792 , where @entity11657 occurred five years before the c- @entity1252 diagnosis.
