Evaluation of the value of the first and third trimester maternal mean platelet volume ( XXXX ) for prediction of @entity1468 .

@entity1 @entity6688 @entity1468
INTRODUCTION: @entity1468 is one of the most serious complications of pregnancy and one of the major causes of maternal mortality. Thus its prediction is a matter for serious concern. OBJECTIVE: The purpose of the present study is to determine the value of mean platelet volume ( @entity6688 ) measurement in the first and third trimesters of pregnancy for the prediction of @entity1468 . METHOD: A prospective nested case-control study was performed on pregnant @entity1 who were at 9-12weeks of pregnancy. In the first trimester and again in 26-28weeks, @entity6688 was calculated. All eligible @entity1 were then monitored to delivery and the @entity6688 of @entity1 who were pre-eclamptic was compared with the @entity6688 of normotensive @entity1 . RESULTS: Pre-eclamptic @entity1 were compared with 269 normotensive @entity1 . @entity6688 at the first trimester of pre-eclamptic @entity1 was significantly higher than normotensive @entity1 (10.2  1.06fl VS 9.68  1.09fl, P=0.008). Also, @entity6688 at the third trimester of pregnancy of pre-eclamptic @entity1 was more than normotensives (10.16  1.23fl VS 9.62  1.12fl, P=0.009). Area under the curve in receiver operating characteristics (ROC) curve was calculated as 0.64 for the predictive value of @entity6688 at the first and third trimesters of pregnancy, which showed a low value of this test for predicting of @entity1468 . CONCLUSION: @entity6688 at the first and third trimesters of pregnancy are higher in @entity1 who eventually would be pre-eclamptic, but has low predictive value and is not a good predictor of @entity1468 .
