Lymph Node @entity3 and Prognosis in Left Upper Division Non-Small Cell Lung Cancers: The Impact of Interlobar Lymph Node XXXX .

@entity1 @entity5 @entity1149 @entity477 @entity3121 @entity3
BACKGROUND: Left upper division segmentectomy is one of the major pulmonary procedures; however, it is sometimes difficult to completely dissect interlobar lymph nodes. We attempted to clarify the prognostic importance of hilar and mediastinal nodes, especially of interlobar lymph nodes, in @entity1 with primary @entity1149 ( @entity1149 ) located in the left upper division. METHODS: We retrospectively studied @entity1 with primary @entity1149 undergoing surgical pulmonary resection (at least lobectomy) with radical lymphadenectomy. The representative evaluation of therapeutic value from the lymph node dissection was determined using Sasako's method. This analysis was calculated by multiplying the frequency of @entity3 to the station and the 5-year survival rate of the @entity1 with @entity3 to the station. RESULTS: We enrolled 417 @entity1 (237 @entity1 , 180 @entity1 ). @entity5 were located in the lingular lobe and at the upper division of left upper lobe in 69 and 348 @entity1 , respectively. The pathological nodal statuses were pN0 in 263 @entity1 , @entity3121 in 70 @entity1 , and @entity477 in 84 @entity1 . Lymph nodes #11 and #7 were significantly correlated with differences in node involvement in @entity1 with @entity1149 . Among those with left upper division @entity1149 , the 5-year overall survival in @entity3121 was 31.5% for #10, 39.3% for #11, and 50.4% for #12U. The involvement of node #11 was 1.89-fold higher in the anterior segment than that in the apicoposterior segment. The therapeutic index of estimated benefit from lymph node dissection for #11 was 3.38, #4L was 1.93, and the aortopulmonary window was 4.86 in primary left upper division @entity1149 . CONCLUSIONS: Interlobar node involvement is not rare in left upper division @entity1149 , occurring in >20% cases. Furthermore, dissection of interlobar nodes was found to be beneficial in @entity1 with left upper division @entity1149 .
