A randomized clinical trial on the effect of low-level laser therapy on chronic XXXX foot wound healing: a preliminary report.

@entity1 @entity1066 @entity6 @entity4760
BACKGROUND AND OBJECTIVES: Low-level laser therapy (LLLT) has been shown to promote chronic wound healing in conditions of reduced microcirculation. In this preliminary study, we report the results of using LLLT to heal foot @entity1066 in @entity1 with @entity6 . MATERIALS AND METHODS: Twenty-three @entity1 with a @entity6 foot wound for at least 3 months were included in this double-blind randomized clinical trial. @entity1 were randomized to receive placebo treatment (n = 10) or LLLT (n = 13) (685 nm, energy density 10 J/cm(2)) in addition to conventional therapy. @entity1 were followed for 20 weeks. Ulcer size reduction and the number of @entity1 with complete healing were compared between the LLLT and placebo groups. RESULTS: There were no significant differences in baseline characteristics of @entity1 and foot @entity1066 receiving LLLT and placebo treatment. At week 4, the size of @entity1066 decreased significantly in the LLLT group (p = 0.04). After 20 weeks, in the LLLT group, eight @entity1 had complete healing and in the placebo group only three @entity1 experienced complete wound healing. The mean time of complete healing in LLLT @entity1 (11 weeks) was less than that in placebo @entity1 (14 weeks) though the difference was not statistically significant. CONCLUSIONS: The study provides evidence that LLLT can accelerate the healing process of chronic @entity4760 , and it can be presumed that LLLT may shorten the time period needed to achieve complete healing.
