The lifetime risk of @entity55 in XXXX with @entity4094 at a mean age of 21  years: the role of spinal deformity surgery.

@entity1 @entity4094 @entity6314 @entity55 @entity1635 @entity302 @entity306
BACKGROUND: @entity1 with @entity4094 often have an increased risk of @entity55 and @entity6314 , which may further be compromised by @entity1635 . @entity1635 surgery may improve pulmonary function in otherwise healthy @entity1 , but no study has evaluated its effect on the risk of @entity55 in @entity1 with @entity4094 ( @entity4094 ). METHODS: The @entity1 charts of 42 @entity1 (mean age 14.6  years) who had undergone surgery for severe @entity4094 (mean @entity1635 86  ) were retrospectively reviewed from birth to a mean of 6.1 years (range 2.8-9.5) after @entity1635 surgery. The main outcome was radiographically confirmed @entity55 as a primary cause for hospitalization. We excluded postoperative (3  months) @entity55 from the analyses. RESULTS: The lifetime annual incidence of @entity55 was 8.0/100 before and 13.4/100 after @entity1635 surgery (p  >  0.10). The mean number of hospital days per year due to @entity55 were 0.59 (SD 2.3) before @entity1635 surgery and 2.24 (SD 6.9) after surgery (p  >  0.10). Multivariate analysis demonstrated that lifetime risk factors for @entity55 were @entity302 (RR 15.2, 95  % CI 1.3-176.8, p  =  0.027), @entity306 ( @entity306 ) etiology (RR  =  10.2, 95  % CI 3.2-32.7, p  <  0.001) and major @entity1635 (main curve >70  ; RR  =  11.3, 95  % CI 1.8-70.7, p  =  0.01). CONCLUSIONS: @entity302 , non- @entity306 etiology and major @entity1635 are significant risk factors for @entity55 in @entity1 with @entity4094 . @entity1635 surgery does not decrease the incidence of @entity55 in @entity1 with severe @entity4094 . LEVEL OF EVIDENCE: Retrospective comparative study, Level III.
