The diagnosis of XXXX : a challenge for rhinologists.

@entity1 @entity32 @entity50 @entity353 @entity706 @entity39 @entity5 @entity1415 @entity4 @entity784 @entity3191 @entity2490 @entity5254 @entity1892 @entity11766 @entity221 @entity8968
The presenting symptoms of @entity706 are usually similar to those of benign inflammatory diseases. Adequate amount of biopsy tissue is required for a definitive diagnosis because @entity5 coexisting with @entity39 or @entity32 is not uncommon. Therefore, the diagnosis of @entity706 is a challenge for rhinologists. Thirty-two @entity1 diagnosed as having @entity706 from 1990 to 2010 in our hospital were included in this study. The presenting symptoms of these @entity1 included @entity8968 , @entity5254 , bloody discharge/ @entity1415 , post nasal drip, @entity4 , neck mass, orbital symptoms, @entity221 , and body @entity353 . The average period between @entity1 ' awareness of their symptoms and their decision to seek medical help was 8.9 months. When they were referred to our hospital, the first impression of 20 @entity1 (62.5%) was benign or @entity5 , and that of the other 12 @entity1 (37.5%) was @entity2490 or rhinosinusitis. These @entity1 then received image studies and biopsy or surgical intervention. Most @entity1 needed repeated biopsies, endoscopic sinus surgery, turbinectomy, or Caldwell-Luc operation for a definitive diagnosis. Their histopathologic classification included @entity784 (n = 13, 40.6%), @entity3191 (n = 12, 37.5%), and diffuse large B cell lymphoma (n = 7, 21.9%). @entity3191 and @entity784 mostly occurred in the nasal cavity, whereas @entity50 without @entity11766 is common in @entity1892 Our results reveal that @entity1 with sinonasal NHL tend to ignore their symptoms until they become serious, and a definitive diagnosis usually requires repeat and deep biopsy.
