@entity12513 in a XXXX with @entity309 .

@entity1 @entity1667 @entity32 @entity12513 @entity1333 @entity310 @entity16 @entity226 @entity786 @entity4932 @entity10 @entity2883 @entity1499 @entity309
@entity1333 of the central nervous system is exceedingly rare in @entity1 with @entity309 ( @entity309 ). The symptoms may be misleading. Most of the reported cases occurred in males with long-standing, nodular, destructive, @entity4932 . Severe constitutional symptoms and prominent extraarticular manifestations of @entity1333 were usually present. We report a case of @entity12513 in a 59-year-old @entity1 with a 20-year history of destructive @entity309 that was well controlled by @entity1499 . @entity10 that was unresponsive to symptomatic treatment developed abruptly, together with gait disorders. Magnetic resonance imaging of the brain showed dot-like areas of high-signal in a periventricular subcortical distribution on both sides. Magnetic resonance angiography visualized a long tight stenosis of the right internal carotid artery and a string-of-beads stenosis of the left internal carotid artery suggesting @entity1333 . Pulse therapy with @entity1667 (1 g/d for 3 days) and @entity786 (1 g) once a month ensured resolution of the @entity16 and laboratory evidence of @entity32 . There was no evidence of a relapse at last follow-up after 5 months. @entity12513 is usually treated with monthly glucocorticoid and @entity786 boluses separated by continuous glucocorticoid therapy. @entity310 antagonists may be effective in @entity1 who fail to respond to conventional treatment. However, other vasculitides such as @entity226 and @entity2883 must be ruled out, as they are refractory to @entity310 antagonist therapy.
