The neuropathology of @entity11460 of central origin (the XXXX ).

@entity1 @entity4094 @entity9576 @entity191 @entity551 @entity11460
The neuropathological features of the " @entity11460 " have, in the past, been unsettled. The position was recently clarified by Oppenheimer who reviewed the 51 reported @entity1 with @entity11460 in whom neuropathological findings were given. He divided these cases into two groups. Group I included those with lesions of the pigmented nuclei of the brain stem which contained Lewy bodies. These he further subdivided into subgroups IA or IB according to whether or not the @entity1 showed clinical evidence of @entity191 in addition to the common denominator of @entity551 . In group II he placed those @entity1 in whom @entity9576 was found at necropsy. These were the majority. Loss of neurons from the intermediolateral columns of the thoracic spinal cord, thought to be the cause of the postural @entity551 , was present in all cases. To illustrate the new classification the necropsy findings in 3 @entity1 taken from the files of the Royal Perth Hospital are described. One of these showed the lesions of @entity191 with Lewy bodies, and thus conformed to Oppenheimer's type IA. The two other @entity1 showed @entity9576 and thus belonged to @entity4094 . All three showed loss of neurons in the intermediolateral columns of the thoracic spinal cord. We believe that Oppenheimer's classification of progressive @entity551 improves the clinicopathological understanding of the syndrome and is thus useful as well as informative to the practising neurologist.
