Pattern of XXXX in Nepal: A single-center experience.

@entity1 @entity8 @entity697 @entity1987 @entity628 @entity1988 @entity3630 @entity1985 @entity631 @entity454
UNASSIGNED: @entity631 ( @entity631 ) is the most common cause of @entity454 in Nepal. The aim of the present study is to determine the clinical presentation and histological pattern of @entity631 with and without immunofluorescence (IF). It is a retrospective analysis of all @entity631 @entity1 with kidney biopsy at the Bir Hospital from January 2000 to April 2009. The clinical presentation, blood pressure, urine analysis, 24-h urinary protein, biochemistry, hemoglobin, antinuclear antibody, anti-ds DNA, light microscopy (LM) and IF findings of kidney biopsies were computed from hospital records. SPSS package was used for analysis. A total of 398 @entity1 [LM 204 (51%) and LM plus IF 194 (49%] were analyzed. The mean age of the study @entity1 was 28    13.6 years (range 7-74); males comprised 52.8% and females 47.2% of the @entity1 ; 51% were between 16 and 30 years of age. The common clinical presentations included @entity1985 ( @entity1985 ), seen in 69% of the @entity1 , followed by @entity697 , seen in 14.4% of the @entity1 . Kidney biopsy without IF showed mesangial proliferative @entity631 (MesPGN) in 21.1%, @entity631 ( @entity3630 ) in 18.6%, @entity8 ( @entity8 ) in 14.2%, @entity1987 ( @entity1987 ) in 12.3% and @entity628 ( @entity628 ) in 9.8% of the cases. With IF, @entity1987 was seen in 23.2%, @entity628 in 18%, @entity8 in 11.9%, @entity8 in 9.8%, MesPGN in 8.2%, @entity3630 in 4.1% and crescentic @entity631 in 3.1% of the cases. @entity1988 in the cases @entity631 was most common in young adults, with the majority presenting with @entity1985 . @entity1987 and @entity628 were the most common glomerular lesions; over-diagnosis of MesPGN and @entity3630 by LM could be due to exclusion of @entity8 .
