Cognitive reserve and persistent XXXX -A prospective mild @entity131 (mTBI) cohort study.

@entity1 @entity131 @entity73 @entity2414 @entity6413 @entity130
PRIMARY OBJECTIVE: Having three or more persisting (i.e. > 3 months) @entity6413 ( @entity6413 ) affects a significant number of @entity1 after a mild @entity131 (mTBI). A common complaint is @entity73 . However, several meta-analyses have found no evidence of long-term @entity73 in mTBI @entity1 . The study sought to answer two questions: first, is there a difference in cognitive performance between @entity6413 and recovered mTBI @entity1 ? Second, is lower cognitive reserve a risk factor for developing @entity6413 ? RESEARCH DESIGN: Prospective inception cohort study. METHODS AND PROCEDURE: One hundred and twenty-two adult @entity1 were recruited from emergency departments within 24 hours of an mTBI. Three months @entity130 , @entity1 completed the Rivermead Post Concussion Symptoms Questionnaire and a neuropsychological assessment. A healthy control group (n = 35) were recruited. The estimate of cognitive reserve was based upon sub-test Information from Wechsler Adult Intelligence Scale and international classifications of educational level and occupational skill level. MAIN OUTCOME AND RESULTS: mTBI @entity1 showed reduced memory performance. @entity1 with lower cognitive reserve were 4.14-times more likely to suffer from @entity6413 . CONCLUSIONS: mTBI may be linked to @entity2414 . Lower cognitive reserve appears to be a risk factor for @entity6413 and indicates individual vulnerabilities.
