Restorative proctocolectomy for XXXX IN 1985-2009.

@entity1 @entity5 @entity5042 @entity254 @entity31 @entity1960 @entity1141
BACKGROUND AND AIMS: Restorative proctocolectomy is the most common operation in @entity1 with @entity31 . The aim was to evaluate long-term changes in our operative treatment and early and late complications related to restorative proctocolectomy. MATERIAL AND METHODS: The study comprised 352 (149 females) @entity1 over 18   years of age with @entity31 who underwent restorative proctocolectomy in 1985-2009 median follow-up time of 5   years. RESULTS: The indication for surgery was active @entity1960 in 168 (47.7%), @entity1960 in 159 (45.2%), and @entity5 or @entity1141 in 25 (7.1%) @entity1 . Ileal pouch-anal @entity254 was performed using hand-sewn @entity254 with mucosectomy in 283 @entity1 and stapled @entity254 in 69. A shift from hand-sewn to stapler ileal pouch-anal @entity254 took place in 2005. Covering ileostomy was carried out in 133 (37.8%) @entity1 . There were 82 (23.3%) J-pouch-related complications. The operative mortality was 0.3%. There were significantly fewer leakages and early re-operations when covering ileostomy was used than when it was omitted: 6.0% versus 16.4% (p   =   0.004), 4.5% versus 11.9% (p   =   0.02), respectively. There were more strictures in hand-sewn than in stapled ileal pouch-anal anastomoses (17.6% vs. 0%, p   =   0.001). @entity5042 occurred at least once in 134 (38.1%) @entity1 . CONCLUSION: The ileal pouch-anal @entity254 technique used in restorative proctocolectomy had changed over the past years from hand-sewn to stapled @entity254 . Covering ileostomy seemed to protect against major complications. @entity5042 was the most common late complication.
