Prognostic factors affecting survival and disease-free survival in lymph node-negative XXXX .

@entity1 @entity440 @entity5 @entity0
BACKGROUND AND OBJECTIVES: The objective of this study was to identify the @entity1 who are at low or high-risk by defining the prognostic factors in node-negative @entity0 . METHODS: Medical records of 384 consecutive @entity0 @entity1 with negative axillary lymph nodes who had been operated on between January 1994 and January 1997 at our hospital were retrospectively reviewed. Several clinical and pathological characteristics of @entity1 were categorized. Univariate analyses of survival and disease-free survival (DFS) were performed by the Kaplan-Meier method and the log-rank test. Independent prognostic and predictive factors affecting survival and DFS were assessed by Cox proportional hazard method. RESULTS: 5-year survival and DFS were 91.4 and 85.7%, respectively. Size, grade, age, and lymphovascular invasion (LVI) were the prognostic factors that independently affected survival and DFS. @entity440 improved survival and DFS. While age younger than 35 was an adverse factor for both survival and DFS, age older than 49 was a detrimental factor for DFS. CONCLUSIONS: @entity1 who have a @entity5 with size greater than 2 cm, with histologic grade 3, with LVI, and @entity1 with age under 35 or older than 49 have poorer prognosis among node-negative @entity0 , and are candidates for adjuvant therapy.
