Correlation between silent cerebral XXXX and left ventricular mass and geometry in essential @entity101 .

@entity1 @entity101 @entity75 @entity1184 @entity22286 @entity4346 @entity62 @entity121
BACKGROUND: It has been proposed that @entity4346 ( @entity4346 ) is related to a worse degree of target organ damage in @entity101 with this feature than in those without. Moreover, the presence of cerebral @entity62 ( @entity62 ) is considered to be an early marker of @entity75 in essential @entity101 . The aim of this study was to assess the association between the presence of silent @entity62 and left ventricular mass and geometry in middle-aged individuals with @entity101 that had never been treated. METHODS: A total of 62 @entity1 (39 @entity1 , 23 @entity1 , aged 50 to 60 years, mean age 54.4 +/- 3.2 years) with never-treated essential @entity101 and without clinical evidence of target organ damage were studied. All @entity1 underwent brain magnetic resonance imaging and were classified into two groups according to the presence or absence of @entity62 . Echocardiography measuring @entity121 ( @entity121 ), @entity22286 ( @entity22286 ) and left ventricular end-diastolic diameter (LVEDD) was also performed. Left ventricular mass index (LVMI) was calculated using the Penn convention criteria, and @entity121 ( @entity121 ) was estimated by the standard formula: 2 x @entity121 /LVEDD. RESULTS: @entity101 @entity1 with @entity62 exhibited significantly higher @entity121 , @entity22286 , LVMI, and @entity121 when compared with @entity101 @entity1 without @entity62 . In addition, 23 of 26 @entity101 @entity1 with @entity62 showed echocardiographic criteria for @entity4346 that was significantly higher than that observed in @entity101 @entity1 without @entity62 (21 of 36; P = .01). @entity1184 ( @entity4346 and @entity121 > or = 0.45) was present in 14 @entity101 @entity1 with @entity62 and in only four @entity1 without @entity62 (P = .002). CONCLUSION: There is a close association between cerebral @entity62 and concentric @entity4346 in asymptomatic middle-aged @entity101 @entity1 , independent of blood pressure values.
