Radiofrequency ablation versus surgical resection for XXXX within the Milan criteria: A study of 281 Western @entity1 .

@entity1 @entity66 @entity72199 @entity5 @entity157
OBJECTIVES: The aim of this study was to compare survival between radiofrequency ablation (RFA) and surgical resection (SR) in @entity1 with @entity157 ( @entity157 ) within Milan criteria. METHODS: From January 2004 to December 2013 we consecutively and retrospectively included all @entity1 with first occurrence of @entity157 within Milan criteria receiving SR or RFA as first-line treatment. The cumulative overall survival (OS) and @entity66 ( @entity66 ) were compared after inverse probability weighting (including confounding factor). RESULTS: A total of 281 @entity1 (RFA 178, @entity72199 ) were enrolled. In multivariate Cox regression RFA and SR were not independent predictors of survival or recurrence. The respective weighted 5 years OS and @entity66 for @entity1 with propensity scores between 0.1-0.9 in the SR and RFA groups were 54-33% and 60-16.9%, P   =   0.695 and P   =   0.426, respectively. Local @entity5 progression rate did not differ according to treatment (P   =   0.523). Major complication rate was higher in the SR group, P   =   0.001. Hospitalisation duration was lower in the RFA group (mean 2.19 days, range 2-7) than in the SR group (mean 10.2 days, range 3-30), P   <   0.001. CONCLUSION: This large Western study has shown that OS and @entity66 did not differ after RFA (using mainly multipolar devices) and SR, for @entity157 within the Milan criteria in a European population, with a shorter hospitalisation time and a lower complication rate for RFA.
