Challenges in the treatment of childhood XXXX .

@entity1 @entity765 @entity81 @entity5
Between 1968 and 1985, we treated 20 @entity1 for @entity81 (also called @entity765 and aggressive @entity81 ). The primary sites included head and neck (seven @entity1 ), extremity (seven @entity1 ), and trunk (six @entity1 ). Lesions ranged from 3 to 18 cm in diameter. The @entity5 were smaller than 5 cm in 13 @entity1 , and in seven @entity1 they were larger than 5 cm. A total resection was not feasible in any of the @entity1 with lesions larger than 5 cm. Ten of the 11 @entity1 treated with wide local resection, in whom the margins were clearly negative or close, remained free of disease for six to 16 years. Nine @entity1 required additional treatment with radiotherapy (nine @entity1 ) and chemotherapy (five @entity1 ). Two died of local disease progression. In the remaining seven @entity1 , the disease was controlled. We describe our strategies for managing this disease in a pediatric population.
