Comparison of endoscopic treatment modalities for XXXX .

@entity1 @entity4906 @entity355 @entity548 @entity5 @entity1372 @entity420 @entity1141
BACKGROUND: There are few data comparing endoscopic treatment outcomes for @entity355 ( @entity355 ). OBJECTIVE: To compare treatment outcomes in @entity355 @entity1 treated with radiofrequency ablation (RFA), RFA after EMR, and porfimer @entity1372 photodynamic therapy (Ps- @entity4906 ). DESIGN: Retrospective, observational study. SETTING: Single tertiary center between 2001 and  2013. @entity1 : A total of 342 @entity355 @entity1 treated with RFA (n  = 119), EMR+RFA (n  = 98), and Ps-PDT (n  = 125). MAIN OUTCOME MEASUREMENTS: Rates of complete remission of intestinal metaplasia (CRIM), @entity355 recurrence, and adverse events. RESULTS: Baseline @entity355 high-grade @entity1141 (HGD) and @entity420 were more common in the Ps-PDT group (89%) compared with the EMR-RFA (70%) and RFA (37%) groups. At a median follow-up of 14.2 months, 173 @entity1 (50.6%) achieved CRIM. CRIM was significantly more common in Ps-PDT @entity1 compared with RFA (P  < .001) and EMR-RFA (P  < .001) @entity1 on multivariable analysis. In @entity1 who achieved CRIM, the rates of subsequent @entity355 recurrence were relatively similar among the 3 groups. Although the rates of @entity548 were similar, strictures were less common in RFA @entity1 (2.4%) compared with EMR-RFA (13.3%, P  = .001) and Ps-PDT (10.4%, P  =.043) @entity1 . CONCLUSION: This study of endoscopic treatment for @entity355 and @entity5 found that complete remission was achieved more often and more rapidly after Ps-PDT with similar disease recurrence rates compared with EMR or RFA. Adverse events were more common after EMR and Ps-PDT. Further studies are required to determine which ablation and resection techniques are ideally suited for each @entity355 @entity1 .
