[Classification of long-term clinical course of ' XXXX ': a 20-year follow-up study at a medical school hospital].

@entity1 @entity162 @entity308 @entity911 @entity716 @entity10963 @entity13521
To study the long-term clinical course and outcomes of @entity716 , 8 @entity1 diagnosed with @entity716 were observed for more than 12 years (mean, 20 years). Retrospective examination was performed, particularly with respect to clinical features at each episode. The overall course of each case was classified as one of the following three types: Type I--"Recurrent @entity911 state" type. @entity1 frequently repeated acute transient @entity911 or dream-like states in a similar way, sometimes and/or for part of the episode accompanied by a floating @entity10963 state. Duration of @entity716 was short, persisting for a few days to about one month. Type II--" @entity13521 similar" type. After a long course of disease, the predominantly early middle-aged @entity1 (30- to 40 years-old) demonstrated fewer original characteristic features of acute @entity911 or dream-like states. Instead, @entity162 or @entity308 episodes tended to predominate. Duration of @entity716 exceeded the duration of type I episodes, to a maximum of about 3 months. Type III--"Appearance of residual state" type. After several episodes characterized by transient @entity911 state during middle age, residual states consisting of a slight @entity308 state, reduced spontaneity and flattening of emotions appear. These states become durable and the periodicity of the disease disappeared. We conclude that the core group of @entity716 @entity1 presents with @entity911 symptoms as a clinical feature of episodes, and with the recurrent @entity911 state type representing the long-term clinical course. "Shift to @entity13521 similar" and "appearance of residual state" types were considered to be derived from the core group, according to the interplay of personality structure and viable dynamics.
