Saturday night fever: a common-source outbreak of XXXX among adults in Hawaii.

@entity1 @entity2462 @entity3082
During the summer of 1977, an @entity3082 of @entity2462 occurred among adults in Hawaii. The highest attack rate was in @entity1 20-24 years old (226/100,000), with almost total sparing of young schoolchildren. A case-control investigation implicated a specific discotheque as a common place of exposure for @entity1 with onset of disease during the @entity3082 peak (chi 2 = 12.9,p less than 0.001). A piano player/singer at the discotheque was the apparent source of the virus transmission. The large number of cases linked to this musician suggests that airborne transmission occurred while he was singing rather than by direct @entity1 -to- @entity1 contact. @entity2462 vaccine was given to 6523 @entity1 in public clinics held during the @entity3082 . Despite screening for pregnancy and birth control usage, 23 @entity1 (3.5/1000) became pregnant within three months after receiving the vaccine. Eleven of 12 @entity1 who reportedly contracted natural @entity2462 while pregnant elected to terminate their pregnancies; the 12th had a normal appearing @entity1 . The susceptibility rate for all adults tested for @entity2462 hemagglutination inhibition antibody was 36.9%, a rate similar to the found in earlier surveys in Hawaii. The occurrence of this @entity3082 confirms the changing epidemiology of @entity2462 with respect to age distribution and supports the view that vaccination of young @entity1 may not be sufficient to protect adult @entity1 from exposure to @entity2462 , especially in areas where a high proportion of adults remain susceptible.
