Infratentorial Microbleeds: Another Sign of Microangiopathy in XXXX .

@entity1 @entity64 @entity6249 @entity5330 @entity2704 @entity1188 @entity62 @entity1779
BACKGROUND AND PURPOSE: @entity2704 is a risk factor for clinical @entity64 and for subclinical @entity62 and @entity1188 . These subclinical lesions are linked to small-vessel pathology. @entity1779 ( @entity1779 ) are another biomarker of @entity6249 but have not yet been studied in @entity2704 . METHODS: Identification of @entity1779 in 63 migraineurs (25 with aura/35 without aura/3 unknown aura status) and 359 controls (aged, 73-85 years) from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) magnetic resonance imaging study. We assessed the modifying role of @entity2704 in the co-occurrence of @entity1779 , @entity1188 , and white matter hyperintensity-load. RESULTS: Infratentorial microbleeds were more prevalent in @entity5330 @entity1 than controls (14% versus 4%). Prevalence of other @entity1779 , @entity1188 , and @entity62 did not differ between groups. Migraineurs with @entity1779 had more often @entity1188 than controls with @entity1779 (65% versus 43%). In comparison with controls with @entity1188 , migraineurs with @entity1188 had more commonly @entity1779 (55% versus 30%). CONCLUSIONS: @entity2704 , notably without aura, is associated with infratentorial @entity1779 at older age. @entity1779 and @entity1188 co-occur more often in @entity2704 than in controls. This supports the hypothesis of small-vessel involvement in @entity2704 pathophysiology.
