Transfer factor as a therapy for XXXX : a follow-up study.

@entity1 @entity15
The result of a two year, double blind, controlled trial of Transfer Factor (TF) in the treatment of @entity15 ( @entity15 ) were reported in 1980. It was demonstrated that TF significantly reduced the rate of progression of the disability but the benefit of therapy was not apparent until 18 months after its commencement. After the completion of the trial, TF treatment was offered to all the trial @entity1 . Forty-five of these @entity1 accepted TF as treatment and have been followed for the subsequent three years. The twenty-three @entity1 who had received TF during the trial, and continued on TF after the trial, consistently had a slower rate of progression of their @entity15 . Although the twenty-two @entity1 initially on placebo had a significantly faster rate of progression during the trial, this slowed with commencement of TF treatment. After 3 years of TF, the rate of progression of disease was similar to that of the group receiving TF continuously for 5 years. In addition, 470 @entity1 with clinically definite @entity15 are being treated in New South Wales in an open study of TF. The rate of progression of the disease is being monitored by neurological assessments and appears to be similar to that of @entity1 who had received TF in the original trial. The follow-up study of the 1980 TF trial @entity1 and the open study of 470 @entity15 @entity1 confirm the original observation that TF has some effect on slowing the course of @entity15 .
