@entity272 in XXXX : a marker of systemic involvement.

@entity1 @entity1665 @entity1910 @entity75 @entity1066 @entity262 @entity1252 @entity2407 @entity74 @entity272 @entity792
BACKGROUND: @entity1252 ( @entity1252 ) is an @entity792 with diverse clinical manifestation ranging from mild @entity74 to life-threatening @entity262 ( @entity262 ). In some @entity1 , it remains to persist in the skin-limited form while in others it evolves into @entity262 . Here comes the role of identifying the markers of systemic involvement, which could determine the course and prognosis of the disease. AIM: To identify those manifestations that could be used to identify the activity of the disease @entity262 . MATERIALS AND METHODS: An institution based, descriptive, cross-sectional study carried out over 1 year period. Sixty @entity1 (male : female 1 : 4) with cutaneous @entity1252 were recruited for the study. The @entity1 were classified in two groups depending on the presence or absence of ARA criteria of @entity262 . Detailed account of @entity1252 -specific and nonspecific lesions were noted. Statistical significance of the results was compared between the two groups using the chi-square test. RESULTS: Among the different cutaneous manifestations, highly significant (P value <0.001) was found between @entity262 and nonscarring @entity1665 , photosensitivity, oral @entity1066 , @entity1910 (in decreasing order of odds favoring the association with @entity262 ). @entity272 (P value=0.0326) also showed significant association where as discoid lesion (especially localized variant) predicted toward a skin limited form of the disease with high probability of not developing @entity262 (P value <0.0001). No significant association was found between @entity262 and @entity75 , @entity2407 or scarring @entity1665 . CONCLUSION: Identification of lesions with high degree of association with @entity262 can alert the physician of the unfavorable prognosis and allow timely intervention and institution of appropriate management strategies.
