@entity1337 following appendicectomy--the value of peritoneal XXXX .

@entity1 @entity32 @entity698 @entity1337 @entity1341 @entity158
PURPOSE: Peritoneal @entity32 is an important feature in many @entity1 presenting with @entity698 . The contribution of peritoneal nerve fibres to @entity158 experienced after appendicectomy has received little attention. METHOD: In this prospective double blind randomized study a consecutive series of 60 @entity1 undergoing appendicectomy for suspected @entity698 were enrolled. A dose of 1.5 mg.kg-1 @entity1341 0.5% was used. Group one @entity1 received the entire dose of @entity1341 subcutaneously. Group two @entity1 received half the dose subcutaneously (s.c.) and half the dose to the peritoneum. @entity158 scores were assessed pre-operatively and at 30 min, 12 and 24 hr post-operatively using a visual analogue scale. Time to first @entity1337 and total @entity1337 requirements in the first 24 hr were recorded. RESULTS: The @entity1 receiving the s.c. combined with peritoneal @entity1341 had a lower @entity158 score 30 min post-operatively (32 +/- 2 vs 54 +/- 4; P < 0.0001), a longer time to first @entity1337 (248 +/- 20 vs 164 +/- 17 min; P = 0.002) as well as lower opioid (68 +/- 5 vs 100 +/- 7 mg; P = 0.0002) and non steroidal analgesic requirements (65 +/- 6 vs 96 +/- 6 mg; P = 0.007) in the first 24 hr post-operatively. CONCLUSION: A combination of s.c. and peritoneal infiltration with @entity1341 is superior to skin infiltration alone in the relief of @entity158 post appendicectomy.
