Outcomes and Prognostic Factors After Emergent Carotid Artery Stenting for Hyperacute XXXX Within 6 Hours of Symptom Onset.

@entity1 @entity64 @entity2806 @entity2998 @entity432
BACKGROUND:: The optimal treatment for hyperacute @entity64 attributable to cervical internal carotid artery (C-ICA) occlusion remains controversial. OBJECTIVE:: This study sought to evaluate clinical outcomes and prognostic factors after @entity2998 ( @entity2998 ) in @entity1 with hyperacute @entity64 within 6 hours of onset. METHODS:: Forty-seven @entity1 with hyperacute @entity64 attributable to @entity432 underwent emergent @entity2998 . Forty-two @entity1 (89.4%) had @entity432 ( @entity432 ). When @entity1 showed remnant M1 or proximal M2 occlusions after @entity2998 , intracranial recanalization therapy was performed by using pharmacologic thrombolysis and mechanical thrombectomy with a Solitaire stent. Clinical and radiologic data were compared between @entity1 with favorable (modified Rankin scale, 0-2) and unfavorable outcomes. Binary logistic regression analysis was used to find independent prognostic factors. RESULTS:: Emergent @entity2998 was successful in all but 1 @entity1 . Seven (16.7%) of 42 @entity1 with @entity432 did not need further treatment, because thrombolysis in @entity2806 >= 2b was achieved immediately after @entity2998 . Of the 35 @entity1 who underwent intracranial recanalization therapy for remnant @entity432 , thrombolysis in @entity2806 >= 2b was achieved in 71.4% (25 of 35). Twenty-six @entity1 (55.3%) had favorable outcomes, and mortality was 6.4% at 3 months. Time from symptom onset to carotid recanalization was inversely and independently associated with a favorable outcome for all @entity1 and for those with @entity432 (P < .05). CONCLUSION:: In our @entity1 group, emergent @entity2998 for hyperacute @entity64 caused by @entity432 seemed to be effective and safe. Time to carotid recanalization was inversely and independently associated with a favorable outcome. ABBREVIATIONS:: ACST, acute carotid stent thrombosisCAS, carotid artery stentingCI, confidence intervalC-ICA, cervical internal carotid arteryCR, carotid recanalizationICH, intracranial hemorrhageIR, intracranial recanalizationIV, intravenousMCA, middle cerebral arterymRS, modified Rankin scaleNIHSS, National Institutes of Health @entity64 ScalertPA, recombinant tissue plasminogen activatorTICI, thrombolysis in cerebral ischemiaTIO, @entity432 .
