SPECT brain perfusion abnormalities in mild or moderate XXXX .

@entity1 @entity131 @entity2414 @entity909 @entity1296 @entity10 @entity25 @entity130
The purpose of this atlas is to present a review of the literature showing the advantages of SPECT brain perfusion imaging (BPI) in mild or moderate @entity131 ( @entity131 ) over other morphologic imaging modalities such as x-ray CT or MRI. The authors also present the technical recommendations for SPECT brain perfusion currently practiced at their center. For the radiopharmaceutical of choice, a comparison between early and delayed images using Tc-99m HMPAO and Tc-99m ECD showed that Tc-99m HMPAO is more stable in the brain with no washout over time. Therefore, the authors feel that Tc-99m HMPAO is preferable to Tc-99m ECD. Recommendations regarding standardizing intravenous injection, the acquisition, processing parameters, and interpretation of scans using a ten grade color scale, and use of the cerebellum as the reference organ are presented. SPECT images of 228 @entity1 (age range, 11 to 88; mean, 40.8 years) with mild or moderate @entity131 and no significant medical history that interfered with the results of the SPECT BP were reviewed. The etiology of the @entity130 was in the following order of frequency: motor vehicle accidents (45%) followed by blow to the head (36%) and a fall (19%). Frequency of the symptoms was @entity10 (60.9%), @entity2414 (27.6%), @entity1296 (26.7%), and @entity25 (8.7%). Comparison between @entity1 imaged early (<3 months) versus those imaged delayed (>3 months) from the time of the accident, showed that early imaging detected more lesions (4.2 abnormal lesions per study compared to 2.7 in those imaged more than 3 months after the accident). Of 41 @entity1 who had mild @entity130 without @entity909 and had normal CT, 28 studies were abnormal. Focal areas of hypoperfusion were seen in 77% (176 @entity1 , 612 lesions) of the group of 228 @entity1 . The sites of abnormalities were in the following order: basal ganglia and thalami, 55.2%, frontal lobes, 23.8%, temporal lobes, 13%, parietal, 3.7%, insular and occipital lobes together, 4.6%.
