Severe @entity2753 and other electrolyte disturbances associated with XXXX .

@entity1 @entity7486 @entity1272 @entity16 @entity1372 @entity933 @entity1371 @entity2753 @entity4687
PURPOSE: The aim of this study is to evaluate @entity1 ' demographics, patterns of presentation and outcomes of admissions with severe @entity2753 and other electrolyte disturbances that are related to @entity7486 . METHODS: @entity1 with severe @entity7486 -related @entity2753 (defined as serum sodium <125 mmol/L) admitted to the Department of General Medicine of a tertiary teaching hospital between 1 July 2006 and 30 June 2009 were evaluated in this study. @entity1 ' characteristics, clinical features of their presentation and other electrolyte disturbances were analyzed retrospectively. RESULTS: Eleven @entity1 were admitted with severe @entity2753 and other electrolyte disturbances associated with @entity7486 use. All @entity1 were female and elderly (age: 81.7    5.8 years). Their mean weight was 59.0    8.8 kg. @entity7486 sustained release (SR) 1.5 mg daily was taken by eight of eleven @entity1 and the others took @entity7486 2.5 mg in combination with @entity4687 . The mean serum @entity1372 concentration on presentation was 110.9    5.9 mmol/L and was associated with findings of @entity1371 in ten @entity1 and @entity1272 in eight @entity1 . All @entity1 presented predominantly with neurological manifestations, @entity933 (six @entity1 ) being the most common. Electrocardiographic changes were common (nine @entity1 ) including prolonged QT interval in six @entity1 . All the @entity1 ' electrolyte abnormalities were corrected without any life-threatening complications. CONCLUSIONS: This study highlights that the use of @entity7486 is associated with severe @entity2753 and other electrolyte disturbances. Therefore clinicians should be aware of severe electrolyte disturbances arising from @entity7486 . New onset of @entity16 such as @entity933 and unsteady gait in the elderly taking @entity7486 should prompt evaluation of their electrolyte profile.
