Effect of XXXX on QTc intervals after acute myocardial infarction.

@entity1 @entity1406 @entity1188 @entity1162 @entity943
The effect of @entity1406 on corrected QT interval (QTc) was studied retrospectively in 111 survivors of AMI below 70 years of age. Prior to discharge the @entity1 were stratified by age, @entity1188 size and @entity943 and randomized. @entity1406 , 100 mg b.i.d., or placebo were given double-blindly to 59 and 52 @entity1 , respectively. QTc intervals were measured four times prior to randomization and three times during the follow-up year. The highest QTc mean was registered on the second day in the CCU. QTc intervals subsequently decreased significantly in both groups between discharge and the three-month control (p < 0.001). @entity1 on @entity1406 had significantly shorter QTc intervals during the follow-up year than those on placebo (0.394 +/- 0.028 vs. 0.406 +/- 0.034 sec, p < 0.001). The QTc-shortening effect of beta-receptor blockade was most marked in @entity1 with @entity1162 at discharge. @entity1 who died suddenly had @entity1162 prior to discharge. In this group the proposed beneficial effect of beta-receptor blockade on QTc interval cannot be evaluated as most of these @entity1 had died before the first control.
