Hemoptysis due to fungus ball after XXXX : A series of 21 cases treated with hemostatic radiotherapy.

@entity1 @entity39 @entity2381 @entity358 @entity1030 @entity378
BACKGROUND: In @entity1 who are not amenable to surgical resection (cavernostomy), it is difficult to achieve palliation of hemoptysis from @entity358 . There are only 9 cases with a short follow-up that have reported the use of radiotherapy for hemoptysis in this scenario. METHODS: A retrospective series of 21 @entity1 with chronic @entity39 pulmonary @entity2381 were treated with radiotherapy (20 Gray) from 1990 to 2002. The outcome measures were the period from @entity378 treatment to the onset of hemoptysis, hemoptysis resolution rate, change in Zubrod performance status after 30  days of the completion of radiotherapy, local failure-free survival, and overall survival. RESULTS: The median time between @entity378 treatment and the onset of hemoptysis due to aspergilloma was 9  years. After radiotherapy, general status improved and the hemoptysis resolved in all @entity1 . During the follow-up period, 4 failures occurred, with a 5-year local failure-free survival rate of 82  % and a 5-year overall survival rate of 59  %. Of these failures, 2 @entity1 died due to recurrence of the hemoptysis, and 2 were rescued (using cavernostomy and reirradiation). The presence of @entity1030 ( @entity1030 ) (p   =   0.021) and female gender (p   =   0.032) were negatively associated with overall survival. None of the variables was related to local control. CONCLUSIONS: Based on these long-term data, radiotherapy is a potential option for controlling bleeding due to fungus balls. Female @entity1 and @entity1030 were associated with lower survival.
