The Italian START-Register on Anticoagulation with Focus on XXXX .

@entity1 @entity64 @entity548 @entity177 @entity955 @entity715
UNASSIGNED: START-Register - Survey on anTicoagulated @entity1 RegisTer - is an independent, inception-cohort, observational, collaborative database aimed at recording prospectively the clinical history of adult patients starting anticoagulant treatment for any reason and using whatever drug. In this article we present the START-Register and give cross section baseline data focusing on @entity955 ( @entity955 ). @entity1 are asked to insert prospectively consecutive @entity1 recorded as electronic file on the web-site of the registry. Required data are: demographic and clinical characteristics of @entity1 , associated risk factors for @entity64 and @entity548 , laboratory routine data, clinical indication for treatment, expected therapeutic range (in cases of treatment with vitamin K antagonists -VKAs). The follow-up is carried out to record: quality of treatment (for @entity1 on VKAs), @entity548 complications, @entity715 events, and the onset of any type of associated disease. To date 5252 @entity1 have been enrolled; 97.6% were on VKAs because direct oral anticoagulants (DOAC) have been available in Italy only recently. The median age was 74 years [interquartile range (IQR) 64-80]; males 53.7%. This analysis is focused on the 3209 (61.1%) @entity955 @entity1 . Mean CHADS2 score was 2.1  1.1, CHADSVASc score was 3.1  1.3;median age was 76 years (IQR 70-81); 168 @entity1 (5.3%) had severe @entity177 [Creatinine clearance (CrCl) <30 ml/min]. Moderate @entity177 (CrCl 30-59 ml/min) was found in 1265 @entity1 (39.5%). The analysis of the START-Register data shows that two-third of @entity1 who started chronic anticoagulant treatment had @entity955 , one-third of them was > 80 years with high prevalence of @entity177 .
