@entity7742 polymorphism of the XXXX gene and @entity101 in Chinese.

@entity1 @entity7742 @entity101 @entity2178 @entity1853 @entity1889
OBJECTIVES: To compare the distributions of the genotypes and alleles of the @entity7742 polymorphism of the @entity2178 gene for @entity101 @entity1 and normotensive controls. DESIGN: A study of association of genetic polymorphisms. SETTING: An outpatient clinic run by a university department handling referrals from primary care. @entity1 : Two hundred and four subjects, 103 normal controls and 101 @entity1 with newly diagnosed or documented @entity101 . METHOD: Genomic DNA was extracted from peripheral blood leucocytes, amplified by polymerase chain reaction and digested with the restriction enzyme Tth 111 I. @entity1853 (M) and @entity1889 (T) alleles were identified after electrophoresis. MAIN OUTCOME MEASURES: Prevalences of @entity2178 genotypes and alleles for @entity101 @entity1 and controls. RESULTS: MM, TM and TT genotypes occurred in 3, 24 and 73% of controls and 1, 22 and 77% of @entity101 @entity1 , respectively. The prevalences of the M and T alleles were 0.15 and 0.85 among controls and 0.12 and 0.88 among @entity101 @entity1 . The prevalences of the @entity2178 genotypes and alleles for controls and @entity101 @entity1 did not differ significantly. CONCLUSIONS: Our findings differed from previous reports and suggested that this polymorphism is not associated with @entity101 in this population.
