XXXX and repeated bout effect following blood flow restricted exercise.

@entity1 @entity121 @entity450
PURPOSE: @entity450 ( @entity450 ) is suggested to be effective in rehabilitation training, but more knowledge is required about its potential muscle damaging effects. Therefore, we investigated muscle-damaging effects of @entity450 performed to failure and possible protective effects of previous bouts of @entity450 or maximal eccentric exercise (ECC). METHODS: Seventeen healthy young @entity1 were allocated into two groups completing two exercise bouts separated by 14  days. One group performed @entity450 in both exercise bouts (BB). The other group performed ECC in the first and @entity450 in the second bout. @entity450 was performed to failure. Indicators of @entity121 were evaluated before and after exercise. RESULTS: The first bout in the BB group led to decrements in maximum isometric torque, and increases in muscle soreness, muscle water retention, and serum muscle protein concentrations after exercise. These changes were comparable in magnitude and time course to what was observed after first bout ECC. An attenuated response was observed in the repeated exercise bout in both groups. CONCLUSION: We conclude that unaccustomed single-bout @entity450 performed to failure induces significant @entity121 . Additionally, both ECC and @entity450 can precondition against @entity121 induced by a subsequent bout of @entity450 .
