Health status predicts long-term outcome in outpatients with XXXX .

@entity1 @entity1187 @entity301 @entity951 @entity453
BACKGROUND: Although @entity1 -reported health status measures have been used as end points in clinical trials, they are rarely used in other settings. Demonstrating that they independently predict mortality and hospitalizations among outpatients with @entity301 could emphasize their clinical value. METHODS AND RESULTS: This study evaluated the prognostic utility of the Seattle Angina Questionnaire (SAQ), a disease-specific health status measure for @entity1 with @entity453 . @entity1 were enrolled in a prospective cohort study from 6 Veterans Affairs General Internal Medicine Clinics. All @entity1 reporting @entity453 who completed a SAQ and had 1 year of follow-up were analyzed (n=5558). SAQ predictor variables were the physical limitation, @entity951 stability, @entity951 frequency, and quality-of-life scores. The primary outcome was 1-year all-cause mortality, and a secondary outcome was hospitalization for @entity1187 ( @entity1187 ). Lower SAQ scores were associated with increased risks of mortality and @entity1187 admissions. Prognostic models controlling for demographic and clinical characteristics demonstrated significant independent mortality risk with lower SAQ physical limitation scores; odds ratios for mild, moderate, and severe limitation were 1.5, 2.0, and 4.0 versus minimal limitation (P<0.001). Odds ratios for mild, moderate, and severe @entity951 frequency were 0.8, 1.2, and 1.6 (P=0.078). The odds ratios for @entity1187 admission among those with mild, moderate, and severe @entity951 frequency were 1.4, 2.0, and 2.2, respectively (P=0.016). CONCLUSIONS: SAQ scores are independently associated with 1-year mortality and @entity1187 among outpatients with @entity301 and may serve a valuable role in the risk stratification of such @entity1 .
