Effect of XXXX versus corticotomy on orthodontic tooth movement: an in vivo study.

@entity1 @entity5015 @entity235 @entity3009
BACKGROUND AND AIM: The aim of the present study is to compare the effect of corticotomy versus @entity5015 injection in @entity1 subjects on rate of tooth movement, anchorage loss and their effect on crest bone height and root length. SETTINGS AND DESIGN: Clinical interventional study. Split mouth design was used. MATERIALS AND METHODS: Study was done on 32 regular orthodontic @entity1 . A volume of 100 mcg of @entity5015 was injected on the right side once in 2 weeks and on the left side corticotomy was performed, and @entity235 retraction was started on both sides simultaneously. The rate of space closure and anchorage loss was assessed with casts. The root length and crestal bone height changes were assed with IOPAs. The comparison of rate of tooth movement, anchorage loss, crestal bone height and root length changes between the sides were statistically analyzed using paired t-test. RESULTS: The average rate of space closure on right side was 0.36 mm/week with a standard deviation of 0.05 mm/week and on the left side average rate of space closure was 0.40 mm/week with a standard deviation of 0.04 mm/week. The difference between the rate of closure between the right side and left where found to be statistically significant (P=0.003). The anchorage loss, the crestal bone height changes and root length changes were not statistically significant. CONCLUSION: The rate of tooth movement was significantly more with corticotomies when compared with given dose of @entity3009 injection.
