Side effects after radiotherapy of age-related XXXX with the Nijmegen technique.

@entity1 @entity8721 @entity2708 @entity2479 @entity4 @entity1781 @entity3193 @entity5861 @entity941 @entity989 @entity1020
BACKGROUND: In a randomized trial concerning radiotherapy for age-related @entity1020 , @entity941 angiograms were taken of controls and @entity1 . In this study the frequency of side effects in eyes receiving radiotherapy with the Nijmegen technique is compared with the findings in the eyes of controls. METHODS: @entity1 receiving treatment were irradiated by two isocentric photon beams in four fractions of 6 Gy that were directed to the macular area at 30 degrees and -30 degrees with regard to the @entity1781 . The most recent @entity941 angiograms of the randomized eyes (32 treated and 31 control eyes) were scored by two independent researchers, using a scoring form with nine features of @entity989 : nonperfusion, macular @entity4 , microaneurysms, @entity5861 , @entity2708 -wool spots, perifoveal @entity8721 , @entity989 , and radiation-associated @entity3193 . The results were graded as: no @entity989 (grade 0), mild @entity989 (grade 1), moderate @entity989 (grade 2), and severe @entity989 (grade 3). RESULTS: In the treated group 6 @entity1 (18.8%) were grade 1, 10 @entity1 (31.2%) were grade 2 and 7 @entity1 (21.9%) were grade 3. In the control group 9 @entity1 (29.0%) were grade 1, 11 @entity1 (35.5%)were grade 2 and 2 @entity1 (6.5%) were grade 3. There were no @entity1 with @entity2479 . CONCLUSION: With the Nijmegen technique a relatively high dose of radiation can be applied to a small retinal area. In only a minority of cases does some evidence of @entity989 occur.
