Overview of XXXX : past, present and future.

@entity1 @entity105 @entity5
In the foregoing articles, the editors of @entity105 have identified the major themes of current @entity105 research and assembled an outstanding group of authors to review these areas. I have been asked to provide a historical overview of past accomplishments and describe how these contributed to the broader efforts to overcome the burden of @entity1 @entity5 . My assignment also included a look into the future. As scientists we formulate hypotheses that attempt to predict the future. Occasionally we are successful. The pioneers of @entity105 research were remarkably successful in predicting the future. Armed with primitive technology relative to today, these scientists studied the biology of @entity105 and conceptualized a framework for @entity5 pathogenesis that virtually everyone working in @entity5 research follows today. The current generation has been charged with filling in the details. In the details lay the future. Together with past accomplishments, these emerging details form a remarkable picture of progress in understanding and application, creating realistic and imminent promise to achieve victory in the fight against @entity5 .
