Intensive Multidisciplinary Treatment of XXXX : A Prospective Evaluation.

@entity1 @entity308 @entity146 @entity148 @entity2531
UNASSIGNED: @entity2531 ( @entity2531 ) is resistant to treatment. In a prospective observational study, we evaluated an intensive multidisciplinary treatment focusing on body-related mentalization and acceptance. @entity1 included in the study were 183 (146 @entity1 , 37 @entity1 ) of 311 eligible @entity1 with chronic severe @entity2531 , referred consecutively to a specialized tertiary care center between 2002 and 2009. Primary outcome measures were somatic symptoms (SCL-90) and health-related quality of life (EuroQol 5-Dimensional [EQ-5D]). These measures were assessed four times before treatment (on intake, twice during an observation period, at start of treatment) and four times after treatment (during follow-up for 2 years). Multilevel analysis was used to separate effects of time (maturation) and treatment. Results revealed significant improvements in SCL-90 somatic symptoms (d = 0.51), EQ-5D index (d = 0.27), and EQ visual analogue scale (d = 0.56). Significant reductions were also observed in SCL-90 @entity148 , @entity308 , and overall psychopathology as well as in medical consumption associated with @entity146 (Trimbos/iMTA Questionnaire for Costs Associated With @entity146 ). Large interindividual differences were found in treatment outcome. The long-term improvement seen in many @entity1 suggests that intensive multidisciplinary tertiary care treatment is a useful approach to chronic severe @entity2531 .
