Prognostic significance of the lymphocyte-to-monocyte ratio in @entity1 with XXXX .

@entity1 @entity32 @entity5 @entity3620 @entity1349 @entity55833 @entity1355
OBJECTIVES: @entity32 plays a key role in the pathogenesis of @entity3620 ( @entity3620 ) as a result of @entity1355 exposure. Several inflammation-based prognostic scores including the lymphocyte-to-monocyte ratio (LMR), Glasgow Prognostic Score (GPS), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) reportedly predict survival in many @entity5 , while the role of LMR in @entity3620 remains unclear. The aim of this study was to evaluate the clinical value of LMR and to compare the prognostic value of these inflammation-based scores in predicting @entity1349 ( @entity1349 ) in @entity3620 . MATERIALS AND METHODS: One hundred and fifty @entity1 with histologically proven @entity3620 were included in this retrospective study. Kaplan-Meier curves and multivariate Cox-regression analyses were calculated for @entity1349 . The area under the receiver operating characteristics curve (AUC) was calculated to compare the discriminatory ability of each scoring system. RESULTS: An elevated LMR was significantly associated with prolonged @entity1349 . @entity1 with @entity55833 .74 had significantly poor survival compared with LMR >= 2.74 (median, 5.0 versus 14.0 months; p=0.000). The LMR consistently had a higher AUC value at 6 months (0.722), 12 months (0.712), and 24 months (0.670), compared with other scores. Multivariate analysis showed that the LMR was independently associated with @entity1349 . CONCLUSIONS: The LMR is an independent prognostic marker for @entity1349 in @entity1 with @entity3620 and is superior to other inflammation-based prognostic scores with respect to prognostic ability.
