Low density lipoprotein cholesterol control status among Canadians at risk for XXXX : findings from the Canadian Primary Care Sentinel Surveillance Network Database.

@entity1 @entity64 @entity101 @entity3657 @entity6 @entity28 @entity741 @entity65
BACKGROUND: To determine the prevalence of uncontrolled LDL-C in @entity1 with high @entity65 ( @entity65 ) risks across Canada and to examine its related factors. METHODS: Non-pregnant adults >20  years-old, who had a lipid test completed between January 1, 2009 and December 31, 2011 and were included in the Canadian Primary Care Surveillance Network (CPCSSN) database were studied. The Framingham-Risk-Score was calculated to determine the risk levels. A serum LDL-C level of >2.0  mmol/L was considered as being poorly controlled. @entity1 with a previous record of a @entity64 , @entity3657 , or an @entity741 were regarded as those under secondary prevention. Logistic regression modeling was performed to examine the factors associated with the LDL-C control. RESULTS: A total of 6,405 high-risk @entity1 were included in the study and, of this population, 68  % had a suboptimal LDL-C, which was significantly associated with the female gender (OR: 3.26; 95  % CI: 2.63-4.05, p   <   0.0001) and no medication therapy (OR: 6.31, 95  % CI: 5.21-7.65, p   <   0.0001). Those with comorbidities of @entity6 , @entity101 , @entity28 , and smokers had a better LDL-C control. Rural residents (OR: 0.64, 95  % CI: 0.52-0.78, p   <   0.0001), and those under secondary prevention (OR: 0.42; 95  % CI: 0.35-0.51, p   <   0.0001), were also more likely to have a better LDL-C control. CONCLUSION: A high proportion of high-cardiac risk @entity1 in Canadian primary care settings have suboptimal LDL-C control. A lack of medication therapy appears to be the major contributing factor to this situation.
