@entity71791 decrease induced by a @entity258 enhances @entity729 in uremic XXXX with @entity2265 .

@entity1 @entity32 @entity35 @entity39 @entity5 @entity78 @entity4613 @entity740 @entity5536 @entity2629 @entity2265 @entity3147 @entity71791 @entity729 @entity1011 @entity460 @entity258
UNASSIGNED: Although dietary @entity4613 restriction is important for treating @entity2265 in @entity1 with @entity740 , it remains unclear whether a @entity258 ( @entity258 ), which includes low @entity4613 , has beneficial effects on @entity3147 , @entity32 , and @entity729 . The effects of @entity258 on @entity32 , @entity3147 , and @entity729 were therefore assessed in @entity35 . @entity35 were fed a normal diet or diets containing 0.3% @entity5536 and low/normal protein and low/high @entity4613 . After 6 weeks, serum and urinary biochemical parameters, systemic @entity32 , and @entity729 were examined. The protective effect of @entity71791 and albumin were assessed in cultured vascular smooth muscle cells. @entity35 fed the diet containing 0.3% @entity5536 developed severe @entity2629 . @entity258 in @entity35 fed high @entity4613 induced @entity3147 (decreases in body weight, food intake, serum albumin and @entity71791 levels, and urinary @entity1011 excretion) and systemic @entity32 (increases in serum @entity5 @entity39 factor-a and urinary oxidative stress marker). @entity258 decreased serum @entity71791 level and @entity71791 synthesis in the liver and increased serum @entity78 precipitates. High @entity4613 diet increased aortic @entity460 content, which was enhanced by @entity258 . Reduced fetal calf serum in the medium of cultured vascular smooth muscle cells enhanced @entity4613 -induced formation of @entity78 precipitates in the media and calcification of vascular smooth muscle cells, both of which were prevented by @entity71791 administration. Our results suggest that @entity4613 restriction by restricting dietary protein promotes @entity729 by lowering systemic @entity71791 level and increasing serum @entity78 precipitates and induces @entity32 and @entity3147 in uremic @entity35 fed a high @entity4613 diet.
