Thoracoscopic and laparoscopic lymph node staging in XXXX : do clinicopathological factors affect the outcome?

@entity1 @entity5 @entity957 @entity1600 @entity1442 @entity418 @entity3 @entity420
BACKGROUND: This study was performed to evaluate the pattern of lymphatic @entity3 found by combined thoracoscopic (TS) and laparoscopic (LS) lymph node staging in @entity418 , and ascertain whether clinicopathologic factors may be used to guide the clinical practice of combined TS and LS staging. METHODS: A retrospective study was performed in a series of 76 @entity418 @entity1 who had undergone both TS and LS staging before treatment. The correlation of TS and @entity1600 with clinicopathologic factors was analyzed, including the clinical T stage, clinical N stage, @entity5 location, and histology. RESULTS: Thirty-one @entity1 (40.8%) were found to have lymphatic metastasis by TS and LS staging. Among them, 22 @entity1 had abdominal lymph node @entity3 , 7 @entity1 had mediastinal lymph node @entity3 , and 2 @entity1 had both. @entity1 with @entity1442 stage (T3 to T4) or @entity420 had a higher frequency of abdominal lymphatic @entity3 than @entity1 with early T stage (T1 to T2) (39% vs 16%; p = 0.04) or @entity957 (39% vs 20%; p = 0.079), respectively. @entity1 with clinical abdominal N1 stage had a higher incidence of positive laparoscopic finding than @entity1 with clinical abdominal N0 stage (67% vs 23%; p = 0.001). There was no significant correlation between lymphatic @entity3 and the location of the @entity5 . CONCLUSIONS: Clinicopathologic factors, including the histologic type, the clinical T stage, and abdominal N stage, may affect the outcome of TS and LS lymph node staging in @entity418 @entity1 . This clinicopathologic impact may play a role for the selection of candidates for TS and LS staging, and also allows surgeons to focus their attention on the most likely high-yield biopsy targets.
