The impact of race on survival in XXXX : a matched analysis.

@entity1 @entity189
OBJECTIVE: To determine if @entity189 ( @entity189 ) exhibits significant prognostic differences in Chinese versus white @entity1 . METHODS: From the Surveillance, Epidemiology, and End Results database for the time period 1988 to 2000, all cases of @entity189 were extracted and staging variables computed. To each case of @entity189 diagnosed in a Chinese @entity1 , a case of @entity189 in a white @entity1 was randomly matched for age at diagnosis, gender, grade, stage, and treatment modality. Kaplan-Meier survival analysis was then conducted for the matched groups comparing overall survival and disease-specific survival both for the overall matched cohort and stage stratified cohorts. RESULTS: Among 1,520 cases of @entity189 , 338 were identified in Chinese @entity1 with staging information. Of these, 171 were successfully matched to white @entity1 . Average age at presentation was 51.5 years with a 3:1 male predominance. Overall survival was substantially better for Chinese @entity1 (mean survival, 94 months; median survival, 95 months) than for white @entity1 (81 months and 64 months, P =.037). Stratified for stage, overall survival was better for Chinese @entity1 for stage 3 but not stage 4 disease (P =.012 and P =.447, respectively). Disease-specific survival was not substantially different between Chinese @entity1 (mean survival, 116 months) and white @entity1 (mean survival 117 months, P =.99). No differences in disease-specific survival were identified for race when stratified by stage (all P >.05). CONCLUSIONS: Although overall survival is better for Chinese @entity1 with @entity189 compared with white @entity1 , disease-specific survival is similar between these racial groups. These data suggest that the biological behavior of @entity189 is relatively independent of race.
