Hysteroscopic local anesthetic intrauterine XXXX in office endometrial ablation: a randomized controlled trial.

@entity1 @entity548 @entity10541 @entity1341 @entity158 @entity282 @entity616
OBJECTIVE: To evaluate the efficacy of a hysteroscopic local anesthetic intrauterine @entity616 (ICOB) on @entity158 experienced during office endometrial ablation (EA) in addition to a traditional direct local anesthetic cervical block (DCB). DESIGN: Prospective, randomized, double-blind, placebo-controlled trial. SETTING: University teaching hospital. @entity1 (S): @entity1 with heavy @entity548 scheduled for an office endometrial ablation. INTERVENTION(S): Before office EA, DCB plus hysteroscopic ICOB just medial to each tubal ostium using local anesthetic mixture made up of 1  mL 3% @entity10541 plus 1  mL 0.5% @entity1341 versus control group receiving DBC plus ICOB with 2  mL of placebo (saline). MAIN OUTCOME MEASURE(S): Primary outcome: @entity158 reported during procedure via visual analogue scale (VAS) from 0 to 10; secondary outcomes: @entity282 , rescue analgesic requirement, and duration of hospital stay. RESULT(S): Most characteristics were similar across groups. The mean VAS score during the procedure was statistically significantly lower by 1.44 (95% confidence interval, -2.65 to -0.21) in the active group compared with the placebo group. There were no statistically significant differences between the two groups in the postprocedural mean VAS scores, rescue analgesic requirement, or duration of hospital stay. CONCLUSION(S): Used in addition to DCB, ICOB reduces the @entity158 experienced during office EA compared with DCB alone. CLINICAL TRIAL REGISTRATION NUMBER: NCT01808898.
