Hepatopancreatoduodenectomy for advanced XXXX .

@entity1 @entity5 @entity189 @entity260 @entity1086
OBJECTIVE: To assess the effectiveness of hepatopancreatoduodenectomy (HPD) in @entity1 with advanced @entity1086 directly invading the liver and pancreas, generally considered to be nonresectable. @entity1 AND METHODS: Sixty @entity1 with @entity1086 admitted to our hospital from 1978 to 1992, of whom 55 had Nevin stage V @entity189 and 21 had resectable @entity5 . Of these @entity1 , seven underwent HPD. The remaining 34 @entity1 had nonresectable @entity5 . The outcomes of @entity1 undergoing HPD and those with nonresectable @entity5 were compared and the effect on their quality of life was also analyzed. RESULTS: @entity260 occurred in five of the seven @entity1 after HPD, but there were no operative deaths. The 1- and 2-year survival rates were 57% and 28.6%, respectively, with a median survival time of 12 months. In contrast, the 1- and 2-year survival rates of the 34 @entity1 with nonresectable @entity5 were both 5.8%, and the median survival time was 2 months. The median and mean durations of home stay after HPD were 6 and 10.5 months, respectively. CONCLUSION: Hepatopancreatoduodenectomy has the potential to improve both survival and the quality of life for carefully selected @entity1 with advanced @entity1086 .
