Acid-base balance in XXXX .

@entity1 @entity4388 @entity1792 @entity3157 @entity520 @entity880 @entity360 @entity413 @entity2388
Acid-base balance has been studied in 21 @entity1 with @entity360 . A low plasma @entity3157 concentration was found in nine @entity1 , accompanied in each case by a base deficit of more than 3 mEq/litre, indicating a @entity520 . Three @entity1 had a low blood pH. Hyperlactataemia appeared to be a major cause of the @entity520 . This was not accompanied by a raised blood @entity2388 concentration. The hyperlactataemia could not be accounted for on the basis of hyperventilation, intravenous infusion of @entity413 , or arterial hypoxaemia. Before blood transfusion it was most pronounced in @entity1 who were clinically shocked, suggesting that it may have resulted from poor tissue perfusion and anaerobic glycolysis. Blood transfusion resulted in a rise in lactate concentration in seven @entity1 who were not clinically shocked, and failed to reverse a severe uncompensated @entity520 in a @entity1 who was clinically shocked. These effects of blood transfusion are probably due to the fact that red blood cells in stored bank blood, with added acid- @entity1792 - @entity413 solution, metabolize the @entity413 anaerobically to @entity880 . Monitoring of acid-base balance is recommended in @entity1 with @entity360 who are clinically shocked. A @entity520 can then be corrected with intravenous @entity4388 .
