Clinical Utility of an Automated Pupillometer in XXXX with Acute @entity75 .

@entity1 @entity1545 @entity428 @entity75 @entity4358 @entity772 @entity2300
OBJECTIVE: The purpose of this study was to evaluate the clinical utility and validity of using a pupillometer to assess @entity1 with acute @entity75 . METHODS: Pupillary examinations using an automated pupillometer (NeurOptics  NPi   -100 Pupillometer) were performed every 4 hours and were simultaneously assessed using the Glasgow @entity772 Scale (GCS) and for @entity428 ( @entity428 ), from admission to discharge or expire in neuro-intensive care unit (NICU). @entity2300 were also recorded for comparison. By comparing these data, we evaluated the validity of using automated pupillometers to predict clinical outcomes. RESULTS: The mean values of the Neurologic Pupillary index (NPi) were different in the groups examined manually. The GCS correlated well with NPi values, especially in severe @entity1545 @entity1 (GCS below 9). However, the NPi values were weakly correlated with @entity428 ( @entity428 ) when the @entity428 was lower than 30 cm @entity4358 . The NPi value was not affected by age or intensity of illumination. In @entity1 with a "poor" prognosis who had a Glasgow Outcome Scale (GOS) of 1 or 2, the mean initial NPi score was 0.88  1.68, whereas the value was 3.89  0.97 in @entity1 with a "favorable" prognosis who had a GOS greater than 2 (p<0.001). For predicting clinical outcomes, the initial NPi value of 3.4 had the highest sensitivity and specificity. CONCLUSION: An automated pupillometer can serve as a simple and useful tool for the accurate measurement of pupillary reactivity in @entity1 with acute @entity75 .
