Symptomatic and asymptomatic high-grade unilateral internal carotid artery XXXX : scalp topography of event-related potentials ( @entity3493 ) and psychometric testing.

@entity1 @entity3881 @entity63 @entity73 @entity3493 @entity731 @entity850 @entity543
Unilateral internal carotid artery (ICA) @entity850 may be accompanied by widespread @entity731 of extra- and intracranial vessels leading to subtle @entity73 . We applied multichannel recording of @entity3493 in 28 @entity1 (68.3 +/- 8.1 years; 15 asymptomatic, 13 with a history of @entity63 ( @entity63 )) and compared them with an age- and sex-matched control group. All underwent a visual "odd-ball paradigm" as well as a psychometric test, the Cognitive Performance Test (CPT), testing mainly visual attention and memory. The potentials were derived from 16 electrodes according to the 10/20 system against linked mastoids. The latencies and amplitudes of N250 and @entity3493 were measured and their amplitudes additionally mapped. Furthermore, the early sensory exogenous potentials, @entity3881 , within the @entity3493 potentials as well as conventional pattern reversal visual evoked potentials (PVEPs) were evaluated. (1) Both the early exogenous potentials and the conventional PVEPs showed no significant differences among all groups. (2) There were no significant differences between asymptomatic @entity1 and those with a @entity63 history in all parameters of the @entity3493 complex so that one total @entity1 group was constructed and compared to the controls. (3) @entity1 ' @entity3493 amplitudes showed significant reductions over hemispheres ipsilateral (P < or = 0.014) and contralateral (P < or = 0.044) to the @entity850 . (4) The N250 amplitudes were reduced only in the central leads (P < or = 0.05). (5) The latencies of N250 potentials were significantly prolonged at many electrodes, not only ipsi-(P < or = 0.0007) but also contralateral (P < or = 0.022) to the @entity850 . (6) The @entity1 ' @entity3493 latencies showed significant lengthening only at occipital sites (P < or = 0.05) compared to controls. (7) In all measured parameters, within the @entity1 group, the differences between hemispheres ipsilateral versus contralateral to the ICA stenoses did not reach statistical significance. (8) The CPT values detected slight @entity73 for both @entity1 groups and they correlated significantly with the latencies in many leads. (9) The highest test sensitivity to classify @entity1 versus controls (z score > 2) was reached in @entity3493 maps of @entity63 @entity1 (77%). An altered @entity3493 indicates electrophysiologically, and @entity73 , subclinical @entity73 even in asymptomatic @entity1 with unilateral tight ICA stenoses. Interestingly, no differences between asymptomatic and @entity63 @entity1 with a high-grade @entity543 could be found.
