Surgical resection for mucosal XXXX in the era of endoscopic submucosal dissection.

@entity1 @entity308 @entity1697 @entity5 @entity1066 @entity1600 @entity7453 @entity356
BACKGROUND/AIM: Endoscopic submucosal dissection (ESD) has been widely performed. The spread of ESD might decrease the rate of gastrectomy for mucosal @entity356 . However, the rate of @entity1 with @entity1600 ( @entity1600 ) might increase, because @entity1 with mucosal @entity356 who had no or a lower risk of @entity1600 underwent ESD instead of gastrectomy. The purpose of the present study was to determine the incidence of @entity1600 and analyze the relationships between @entity1600 and clinicopathological findings of mucosal @entity356 that are included among the extra indications for ESD. METHODOLOGY: Three-hundred sixty @entity1 with pathologically diagnosed as mucosal @entity356 who underwent gastrectomy between September 2002 and April 2009 were analyzed. RESULTS: Of 360 @entity1 with pathologically diagnosed mucosal @entity356 , 34 had initially undergone ESD. Before initial treatment, 202 @entity1 (56.1%) were diagnosed as having @entity1697 , and lymph node involvement was observed in 23 @entity1 (6.4%). Female sex, @entity1066 , and @entity7453 had a significant association with @entity1600 by univariate analysis. All 23 @entity1 with @entity1600 had a macroscopically @entity308 . When the possible indicators of @entity1600 were entered into the multivariate logistic regression analysis, female sex and @entity7453 were significantly correlated with @entity1600 . CONCLUSION: In cases in which the @entity5 is macroscopically depressed and the histological diagnosis from ESD reveals @entity7453 , standard D2 or D1+beta lymphadenectomy should be performed because of the high incidence of @entity1600 .
