Relation of the functional and structural fundus changes after submacular surgery for neovascular age-related XXXX .

@entity1 @entity227 @entity1940 @entity941 @entity1020 @entity1019
AIMS: This study was carried out to investigate the precise pattern of @entity227 associated with subfoveal @entity1940 and the mechanism by which vision is stabilised or improved after submacular surgery. METHODS: Preoperative and postoperative quantitative microperimetry using the scanning laser ophthalmoscope was performed on six eyes of five @entity1 with age-related @entity1020 who underwent subfoveal @entity1940 . The relation of the microperimetry findings to the preoperative and postoperative @entity941 angiographic features was also assessed. RESULTS: Four of the six eyes had visual improvement by the 6 month postoperative visit; the other two had stabilisation of vision at the preoperative level. Despite these beneficial visual effects, none of the @entity1 fixated within the bed of the excised @entity1940 . Subfoveal choroidal membrane excision was associated with a 36% average increase in the @entity1019 at the 1 month postoperative visit, compared with the preoperative size. The postoperative @entity1019 appeared to remain stable or decreased slightly in size between the 6 month and 1 year postoperative visits. @entity227 was associated with the development of a more stable preferred eccentric fixation locus, of which the distance from the centre of the foveal avascular zone was related to @entity227 . Most of the eccentric fixation loci were inferotemporal to the bed of the excised @entity1940 . The surgical retinotomy site was associated with persistent postoperative relative @entity1019 in five of the six cases, but resolved in one @entity1 after 1 year. CONCLUSION: These findings indicate that quantitative scanning laser ophthalmoscope microperimetry may aid in the surgical planning of subfoveal @entity1940 .
