[Severity and extent of XXXX and their relationship to left ventricular functional reserve in the chronic disease state].

@entity1 @entity583 @entity66 @entity63 @entity14501 @entity453
Our previous observations showed that left ventricular wall motion abnormality (asynergy) induced by stress was observed in the phase response of radionuclide technique, and the severity and extent of @entity453 ( @entity453 ) assessed by the Pujadas score (PS) correlated well with the maximal phase delay response (delta MPD) but not with the ejection fraction response (delta EF) in @entity1 with @entity453 without old @entity583 ( @entity583 ). This study evaluated the usefulness of EF, MPD and the first-third filling fraction (FF, divided by the volume accrued throughout diastole) at rest and during stress, using ergometer and first-pass radionuclide angiocardiography (RNA), to determine the severity of @entity453 , and to evaluate any @entity66 and diastolic coupling in left ventricular function during stress. Seventy-four @entity1 with significant @entity453 , including 41 with previous @entity583 ( @entity583 group) and 33 without @entity583 (angina group) were the subjects of this study. EF at rest and during stress inversely correlated, and @entity14501 on stress linearly correlated with PS in angina group with PS greater than 10, while no such correlations were found in @entity583 group. A normal EF response (delta EF greater than or equal to 5%) was accompanied by a greater-than-normal response in FF (delta FF) in both groups. A lower EF response was accompanied by a smaller delta FF in angina group, but by a larger delta FF in @entity583 group. The difference was statistically significant (p less than 0.03), without significant differences by age, PS, peak heart rate, systolic blood pressure, and @entity63 on ECG during stress. Resting EF and FF by the RNA method correlated with those by left ventriculography (LVG), respectively. It was suggested that RNA is an accurate method for determining EF and FF, while phase analysis may provide some additional information different from that provided by LVG. We concluded that EF and MPD during stress are as useful as delta MPD with the exception of a few cases in predicting the severity of @entity453 , and that scar tissue within the ventricular wall in @entity583 may play an important role in determining the ventricular diastolic mechanical property during stress.
