Effectiveness of plant-derived XXXX on demineralization on enamel and dentin under artificial cariogenic challenge.

@entity16377 @entity6559 @entity2722 @entity1547 @entity1388 @entity291
@entity1547 is considered a disease of high prevalence and a constant problem in public health. @entity16377 ( @entity6559 ) are substances that have been the target of recent studies aiming to control or treat caries. OBJECTIVE: The aim of this in vitro study was to evaluate the efficacy of a treatment with @entity2722 , under cariogenic challenge, to minimize or even prevent the onset of caries in the enamel and dentin. MATERIAL AND METHODS: Blocks of enamel and dentin (6.0x6.0 mm) were obtained from @entity291 central incisors, polished, and selected by analysis of surface microhardness (SH). The blocks were randomly divided into 3 groups (n=15), according to the following treatments: GC (control), @entity2722 ( @entity2722 ), GF ( @entity1388 - 1,000 ppm). The blocks were subjected to 6 daily pH cycles for 8 days. Within the daily cycling, the specimens were stored in buffered solution. The blocks were then analyzed for perpendicular and surface hardness and polarized light microscopy. RESULTS: The means were subjected to statistical analysis using the ANOVA and Fisher's PLSD tests (p<0.05). For enamel SH, GF showed the highest hardness values. In the dentin, GF was also the one that showed higher hardness values, followed by @entity2722 . Regarding the cross-sectional hardness values, all groups behaved similarly in both the enamel and dentin. The samples that were treated with @entity2722 and @entity1388 (GF) showed statistically higher values than the control. CONCLUSION: Based on the data obtained in this in vitro study, it is suggested that @entity2722 inhibits demineralization of artificial @entity1547 in both the enamel and dentin, but in a different scale in each structure and in a smaller scale when compared to @entity1388 .
