Effects of XXXX on sweat gland function during heat acclimatization.

@entity2847 @entity1369 @entity26 @entity1372 @entity4090
This study examined the involvement of the hormones @entity1369 and @entity4090 in sweat gland function during heat acclimatization. Two groups of male subjects (n = 8) were tested - one receiving a placebo (control), the other receiving @entity2847 . Both groups performed cycle ergometer exercise at 50% of maximal @entity26 uptake over 10 consecutive days in an environmental chamber maintained at 39 degrees C and 30% relative humidity. Duration of exercise was 90 min on days 2-4 and 6-9, and 45 min on test days 1, 5 and 10. Electrolyte concentrations were determined by total body washdown. @entity4090 increased (p less than 0.001) during exercise on day 1 in the control group but not on days 5 and 10. In contrast, @entity4090 was suppressed by @entity2847 and did not rise in response to exercise or heat exposure. Plasma @entity1369 increased during exercise in both groups, showing no differences between groups. The @entity1372 concentration in sweat decreased significantly (p less than 0.05) in the control group from day 1 to 10 but was unchanged in the treatment group. These data suggest that acclimatization-related changes in sweat gland function may be attenuated by increases in central dopaminergic activity and implicate @entity4090 in control of sweat gland function.
