Validity and reliability of the minimum basic data set in estimating nosocomial XXXX caused by rotavirus.

@entity402 @entity1 @entity697 @entity35096
UNASSIGNED: Introduction: Rotavirus is the principal cause of nosocomial @entity697 (NAGE) under 5 years of age. The objectiveis to evaluate the validity and reliability of the @entity402 ( @entity402 ) in estimating the NAGE caused by rotavirus (NAGER) and to analyze any changes during the three years that the Rotarix   and Rotateq   vaccines were used in Spain.Material and methods: A descriptive, retrospectivestudy was carried out in the University Hospital of @entity35096 (Spain) between 2003-2009 using the @entity402 , positive microbiological results for rotavirus (PMRs), and medical histories.Three methods of estimation were used: 1) An ICD-9-CM code 008.61 in the secondary diagnosis fields (DIAG2) of @entity402 ; 2) method 1 and/or PMRs with a current or recent hospitalization; and 3) the reference method or method 2 contrasted with @entity1 medical histories. The validity of methods 1 and 2 was determined -sensitivity, specificity, predictive values and likelihood ratios (LRs)-, along with their agreement with method 3 (Kappa coefficient). In addition, the incidence rate ratio between the NAGER rate in 2007-2009 (commercialization period of both vaccines) was calculated with respect to 2003-2005 (precommercialization period).Results: Method 1 identified 65 records with a DIAG2 of 008.61. Method 2 found 62 probable cases, and the reference method, 49 true cases. The sensitivity of the @entity402 was 67 %,the positive predictive value was 51 %, and both negative LR (LR-) and reliability were moderate (LR- 0.33, Kappa coefficient 0.58). During 2007-2009, the NARGE decreased by 5 cases per 103 hospitalizations and by 9 per 104 days of hospitalization. Method 2 overestimated both the decline in incidence by 2 per 103 hospitalizations and the decreased risk per day of stay by 10 %. The @entity402 found no differences between the two three-year periods, but, like method 2, showed an excellent level of diagnostic evidence (LR+ 67).Conclusion: The @entity402 taken together with microbiological results, is more exact, safer and more reliable than the @entity402 alone in estimating NAGER; and more useful in ruling out it. Nevertheless, the @entity402 alone may be used to estimate and compare such disease in contexts with different prevalences.
