[Clinical analysis of large and/or invasive XXXX ].

@entity1 @entity5 @entity977 @entity3 @entity583 @entity652 @entity204
To establish a more reasonable therapeutic guide line for large and/or invasive @entity977 , 257 cases of @entity977 were analyzed. Among 83 cases with slight or moderate suprasellar extension (Wilson's Grade II-A _ B) in the pre-CT era, 57 @entity1 were alive at the time of follow-up (mean follow-up period: 12.7 years). Death of unspecified causes other than @entity5 , @entity583 , etc. were reported in nine @entity1 . Among 60 cases of Grade II-A _ B in the post-CT era, 59 @entity1 were alive (mean follow-up: 3.4 years). Comparing these groups, cases with huge suprasellar extension (Grade C) had much worse prognosis. Only two @entity1 were alive among 14 cases of Group C in the pre-CT era. Seven cases of @entity204 with unspecified causes were reported. In the 13 cases of Group C in the post-CT era, 12 @entity1 were alive but at least four of them were severely handicapped. In 10 cases with @entity3 (Grade IV) in the pre-CT era, only two were alive. In the group of Grade IV in the post-CT era, one @entity1 died and three @entity1 were operated repeatedly. Severe complications of irradiation therapy occurred in seven @entity1 (mean interval: 6.6 years) among 120 cases of irradiated @entity977 in every category. Among six cases with histological malignancy, three were operated repeatedly; among the latter group, two @entity1 died and the third showed intracranial @entity3 . The present data indicate that large and/or invasive @entity977 have a pessimistic prognosis, although @entity652 with mild or moderate simple suprasellar extension have fairly good prognosis.(ABSTRACT TRUNCATED AT 250 WORDS)
