Modern management of XXXX .

@entity2720 @entity1 @entity309 @entity158
The management of @entity309 can be challenging even to the most experienced and astute physician. The rheumatoid inflammatory process can be profound, ravaging, and unremitting, and the illness is notorious for its protean manifestations and capricious course. Moreover, the response to therapy is unpredictable, although it can be quite successful in many cases. Nevertheless, the intense @entity158 , profound disability, progressive destructive @entity2720 , and negative psychological milieu that haunt @entity1 demand that something be done therapeutically. @entity309 responds best to a symphony of therapeutic modalities including drugs, rehabilitation, joint surgery, and attention to psychosocial issues. The foundation of any successful therapeutic venture is an educational program designed, however simply, to imbue the @entity1 and family with an understanding of the disease and its course and treatment, and with realistic expectations. Drug therapy is often polypharmaceutical, employing analgesics, nonsteroidal anti-inflammatory agents, both local and systemic corticosteroids, and remission-inducing drugs. Pacing of lifestyle, physical and/or occupational therapy, vocational guidance, psychological and sexual counseling, and social intervention are as much a part of modern management in @entity309 as are drugs. The extra-articular (systemic) manifestations are addressed in a variety of ways depending upon the type and severity of involvement. Although most @entity1 can be treated by their primary care physician, some may require the expertise provided by a specialist. Finally, despite the lack of a cure for @entity309 , most @entity1 respond well to treatment and return to their desired activities of daily living.
