Haematological changes and state of hydration during delirium XXXX and related clinical states.

@entity1 @entity167 @entity14935 @entity716 @entity1068 @entity68
In order to obtain some information about the state of hydration and possible haematological changes in @entity1 with delirium @entity14935 (grade 3) and related clinical states (grade 2) various clinico-chemical variables were measured at the time of admission and repeatedly until clinical recovery from the @entity716 state. In grade 3 @entity1 plasma protein concentration, blood haemoglobin concentration, blood haematocrit and erythrocyte count decreased between admission and recovery probably reflecting a slight haemodilution. The changes were all within the normal range for the variables and there was thus no indication of hypo- or hypervolemia. Delirium @entity14935 @entity1 without concomitant somatic diseases should not be routinely treated with intravenous fluid therapy. In grade 2 @entity1 no statistically significant changes occurred in the above mentioned variables. In the grade 3 @entity1 there was a dramatic (100%) increase in plasma @entity68 concentration between admission and the subsequent morning and this was probably related to the elimination of @entity1068 from the body. In grade 2 @entity1 , where the initial blood @entity167 concentration was lower than in grade 3 @entity1 , no change in plasma @entity68 concentration occurred. A statistically significant increase in reticulocyte count between admission and recovery in both grade 3 and grade 2 @entity1 probably reflected the recovery of haemopoietic tissue from the insult of the preceding @entity1068 intoxication. The same may be true for the prevailing anisocytosis, whereas the trend towards leucocytosis may be due to unspecific stress during the @entity1068 withdrawal reaction. The rapid changes in some of the clinico-chemical variables stress the importance of initiating investigational procedures immediately at the hour of admission.
