XXXX is associated with intrauterine growth and @entity281 .

@entity1 @entity66 @entity281 @entity2099 @entity1468 @entity2241
To investigate whether factors in the fetal or neonatal period influence the risk of later development of @entity66 we conducted a population-based register study. The Swedish Medical Birth Register was linked with the Hospital Discharge Register and identified 3392 singleton @entity1 born in the period 1987-97 who developed @entity66 . Perinatal data for these @entity1 were compared with all @entity1 born in these years. Exposure variables: Maternal age, parity and smoking habits in @entity2099 , @entity1468 , pregnancy duration and birthweight, birthweight by gestational week, Apgar score, neonatal @entity281 , @entity2241 group incompatibility, exchange transfusion, phototherapy. Odds ratios and test-based confidence intervals were calculated. Analyses were made with stratification for year of birth and other risk factors. The risk of developing @entity66 decreased with maternal age and was lower in first-born than in second-born @entity1 . Maternal smoking in @entity2099 was a weak risk factor, as was low birthweight. The most evident risk factors were being exposed to @entity281 (OR = 1.52, confidence limits 1.19: 1.95) and being small for gestational age (OR = 1.45, confidence limits 1.20; 1.75). These risk factors were independent of each other. CONCLUSIONS: We have demonstrated that the intrauterine environment, mainly as mirrored by a low birthweight for gestational age and, independently, @entity281 diagnosis, is associated with the risk of developing @entity66 , supporting the idea of a multifactorial aetiology of the disease.
