Blood flow-restricted walking in older @entity1 : does the acute hormonal response associate with XXXX ?

@entity2124 @entity1 @entity1063 @entity2086
UNASSIGNED: Low-load exercise can increase serum hormones such as @entity2124 ( @entity2124 ) concentration in young adults when combined with blood flow restriction (BFR), but it is unclear whether walking with BFR (BFR-walk) can elevate them for older adults. Furthermore, it remained untested whether changes in these purported anabolic hormones contribute to BFR-walk-induced @entity2086 . To examine the relationship between the acute and chronic effects of BFR-walk, seven @entity1 (age: 64      2  years) performed treadmill walking with (BFR-walk) and without BFR (CON-walk) at 45% of heart rate reserve for 20  min in a randomized crossover design. During BFR-walk, subjects wore 5-cm cuffs on the proximal part of the upper legs. Blood samples were taken before (PRE), immediately after (POST-1) and 15  min post (POST-2) exercise. There was a main effect of time for @entity2124 (P<0  01) with levels increasing following exercise. In addition, there was a condition and time main effect for insulin; with insulin increasing to a greater degree with BFR at POST-2. Noradrenaline increased across time for both BFR-walk (P  =  0  012) and CON-walk (P<0  001); but BFR-walk induced greater elevations at POST-1 and POST-2. The change in @entity2124 , insulin and @entity1063 was not significantly correlated with BFR-walk-induced @entity2086 . These preliminary results suggest that the BFR-walk-induced elevation in the purported anabolic hormones may not have a large impact on muscle growth.
