XXXX with a granuloma-like component occurring in a large colony of @entity35 .

@entity39 @entity5 @entity2 @entity2058 @entity35
@entity5 from a large colony of over 2000 @entity35 were reviewed by a panel of pathologists under the auspices of Universities Associated for Research and Education in Pathology, In the course of this study, a distinct @entity5 in 105 @entity35 was segregated and given the name " @entity2058 ." This report describes the histologic features and anatomic distribution of the @entity5 , along with its incidence by age and sex of the @entity35 . The @entity5 is characterized by a spectrum of histologic patterns, one extreme resembling a sarcomatous process and the other a granulomatous process. The exact morphologic composition varied from animal to animal, as well as in @entity5 from the same animal. The sarcomatous pattern is composed of sheets of uniform cells, occasionally exhibiting phagocytosis. The granulomatous pattern contains epithelioid histiocytes, central areas of @entity5 @entity39 surrounded by palisading cells, and multinucleate giant cells. The liver is the organ most commonly containing @entity2058 , both in animals with @entity5 and in those with involvement of only one organ. Hepatic invasion is typified by expansion of the portal areas and infiltration of the sinusoids by @entity5 cells. The lung is the second most common site. The distribution of @entity2 is bronchiolocentric and angiocentric. Other common sites included the lymph node and spleen, along with large soft tissue @entity5 of the mediastinum and retroperitoneum. Although occasional previous reports apparently have described a similar or identical @entity5 under varying names, no large group of @entity5 of this unique type in @entity35 has been studied and characterized previously.
