Augmenting XXXX after cesarean delivery: use of an adjuvant biologic graft placement in an ovine model.

@entity32 @entity742 @entity2318 @entity1870 @entity446
We sought to reduce long-term complications after cesarean delivery by improving @entity446 . Eight @entity742 (three with twins) underwent cesarean delivery. Hysterotomy sites were repaired in equal parts by suture alone or suture with a juxtaposed graft (Cook Medical, Bloomington, IN). At 90 days postsurgery, scar characteristics and tensile strength testing were assessed. The mean hysterotomy closure time was on average 1 minute, 14 seconds longer for those undergoing graft placement ( P=0.36). The mean scar thickness was 3.0        0.4 mm for controls versus 3.8        1.2 mm for the intervention group ( P=0.047). Tensile strength testing did not demonstrate a significant difference between groups. Histological examination of the @entity2318 showed no significant differences in inflammatory reaction or endometrial inclusions; however, neoangiogenesis was significantly enhanced. Myometrial repair incorporating a graft increased scar thickness and neoangiogenesis. This methodology did not incite @entity1870 or enhance @entity32 within the scar.
