Is adenocarcinoma of the gastric cardia a distinct entity independent of XXXX ?

@entity1 @entity355 @entity5 @entity1600 @entity189 @entity420
@entity189 has been defined diversely. The purpose of this study was to determine whether @entity189 should be categorized as a distinct entity independent of @entity189 . We retrospectively analyzed 65 @entity1 undergoing resection for @entity420 involving the esophagogastric junction (EGJ) with the @entity5 center within 5 cm of the EGJ. @entity420 of the EGJ were classified into Type I, Type II, and Type III according to Siewert's criteria. There was only one @entity420 , and it was associated with @entity355 . No @entity5 had their center between 1 cm and 2 cm proximal to the EGJ. Clinicopathologic features and prognosis were compared among @entity1 with @entity420 ( n = 31), @entity1 with @entity420 ( n = 33), and @entity1 with @entity420 in the upper third of the stomach not invading the EGJ ( n = 153). Siewert's @entity420 was associated with a higher male/female ratio and with higher incidences of well-demarcated appearance and differentiated histology than @entity189 of the upper third of the stomach without esophageal invasion. Lymph nodes along the greater curvature and parapyloric nodes were rarely involved in @entity5 . Within the pT2 category, @entity1 with Siewert's @entity5 showed a higher incidence of @entity1600 and a significantly lower survival rate than did @entity1 with @entity5 of the upper third of the stomach without esophageal invasion. In conclusion, @entity189 , appropriately defined as @entity420 with its epicenter between 1 cm proximal and 2 cm distal to the EGJ, should be categorized as a distinct entity.
