Near-infrared spectroscopy analysis of @entity75 in XXXX .

@entity1 @entity558 @entity75 @entity9555 @entity161
BACKGROUND: Previous studies have shown that near-infrared spectroscopy (NIRS) has high temporal resolution, requires little restraint, and is suitable for examining the effect of psychological tasks on brain circulation. In the present study, frontal function in @entity161 @entity1 was analyzed by NIRS during random number generation (RNG), ruler-catching (RC), and sequential finger-to-thumb (SFT) tasks. METHODS: Two sets of NIRS probes were attached to the foreheads of 13 @entity161 @entity1 and 10 control subjects approximately at Fp1-F7 and Fp2-F8. Near-infrared spectroscopy was conducted at a sampling rate of 1 Hz, with the pathlength being determined by time-resolved spectroscopy with differential pathlength factor measurements. The absolute changes in oxygenated (oxy-Hb) and deoxygenated (deoxy-Hb) hemoglobin concentrations in response to each task were measured, and total hemoglobin (total-Hb) concentration was calculated as the sum of the two. RESULTS: During RNG task, total- and oxy-Hb concentrations increased, and deoxy-Hb decreased, but the responses were significantly smaller in @entity161 @entity1 . During RC task, oxy-Hb in @entity161 @entity1 tended to decrease, in contrast to the mostly increasing response in control subjects. No group difference was observed during SFT task. CONCLUSIONS: Task-dependent profile of functional abnormalities was observed in @entity9555 . These results support the usefulness of NIRS data in @entity75 and evaluating @entity558 in @entity161 @entity1 .
