Evaluation of the morphology of XXXX invasion and its volume in early @entity356 .

@entity1 @entity3578 @entity5 @entity75 @entity895 @entity3 @entity356
BACKGROUND: The aim of the present study was to evaluate the clinical importance of the morphology of @entity5 invasion and its volume in early @entity356 . MATERIALS AND METHODS: The subjects were 92 @entity1 with a single lesion of early @entity356 , who underwent gastrectomy with dissection of lymph nodes, and in whom the lesion was histologically-diagnosed as early @entity356 with @entity3 . The volume of lesions (Vsm, S: < 50 mm3, L: > = 50 mm3) was determined by reconstructing @entity75 by the surface rendering method using pathological tissue sections (mean, 3.6 sections/lesion). The relationships between the volume of lesions and lymph node @entity3 and between conventional clinicopathological parameters and lymph node @entity3 were evaluated. RESULTS: Lymph node @entity3 was observed in 18 @entity1 (20%). The depth of @entity3 was 1.7 +/- 1.4 mm (mean +/- S.D.; range, 0.2-7.5 mm). @entity895 (depth of @entity5 invasion < 0.5 mm) was observed in 11 @entity1 (12%), and @entity3578 (depth of @entity5 invasion > = 0.5 mm) in 81 @entity1 (88%). The mean Vsm was 104.1 +/- 215.4 mm3 (0.4-1,730.5 mm3). Fifty-seven @entity1 (62.0%) were in group S, and 35 @entity1 (38.0%) in group L. There was a significant difference between lymph node @entity3 and Vsm (S vs. L) alone (p = 0.006). Logistic regression analysis also demonstrated that Vsm alone was correlated with lymph node @entity3 (p = 0.005; odds ratio, 1.27; 95% confidence interval, 0.074-0.401). CONCLUSION: The volume of @entity75 in early @entity356 is important for evaluating lymph node @entity3 .
