Benign hepatic nodules in XXXX : radiologic-pathologic correlation with emphasis on the central scar.

@entity1 @entity4383 @entity3619 @entity3181 @entity1575 @entity157 @entity99
OBJECTIVE: The purpose of this study was to determine the imaging features of benign hepatic nodules in @entity1 with @entity3181 and to correlate them with pathologic findings, with special attention placed on the presence of a central scar. MATERIALS AND METHODS: Imaging findings of 59 benign hepatic nodules in four @entity1 with chronic @entity3181 were analyzed retrospectively, and radiologic- pathologic correlation was performed in three @entity1 with 50 hepatic nodules who underwent liver transplantation. All @entity1 underwent multiphasic helical CT. In three @entity1 with 29 lesions, MR imaging, including a multiphasic dynamic study, was performed. The CT and MR imaging findings in these @entity1 were compared with those of 103 small @entity157 in 56 other @entity1 (54 of them displayed @entity3619 or @entity1575 associated with @entity99 but none had @entity3181 ). Image analysis was performed by two radiologists with no knowledge of the diagnosis. RESULTS: All @entity1 with @entity3181 exhibited multiple benign nodules up to 3 cm in diameter, and 42 of 59 lesions were hypervascular. Microscopically, 15 of 32 nodules demonstrated a central scar; moreover, some nodules closely resembled @entity4383 . Frequencies of hyperintensity on T1-weighted images (14/29 vs 25/103), hypointensity on T2-weighted images (7/29 vs 1/103), and the presence of a central scar (6/59 vs 1/103) were significantly higher in benign nodules than in @entity157 (p < 0.05; Fisher's exact test). Moreover, for lesions larger than 1 cm, imaging studies revealed a central scar in six of 15 benign lesions. CONCLUSION: Benign hepatic nodules in @entity1 with in @entity3181 are usually small, multiple, and hypervascular. The presence of a central scar is a characteristic feature in those larger than 1 cm in diameter.
