[Asymptomatic XXXX - 3 cases (author's transl)].

@entity1 @entity322 @entity101 @entity6 @entity9326 @entity1269 @entity1653 @entity1188 @entity1576 @entity4794 @entity2414 @entity15
@entity15 ( @entity15 ) cases found at autopsy in @entity1 who had died from other diseases and in whom no sign or symptom could be related to @entity15 are called "asymptomatic". Three cases are reported. The first @entity1 was a 62 year old @entity1 who presented with a slowly progressive disturbance of gait, @entity322 and deterioration of intellectual function. A @entity1653 was surgically removed. The @entity1 died 3 years later with an acute @entity1576 . Examination of the brain disclosed evidence of the operation and numerous old plaques disseminated through the cerebral hemispheres (centrum semi-ovale, periventricular regions, internal thalamus and junction between cortex and white matter) and in the brain stem. The second case, a 77 year old @entity1 with @entity6 and @entity101 , presented with @entity2414 of acute onset. She died one year later. Examination of the brain showed @entity1188 involving the territories of both posterior cerebral arteries and the left middle cerebral artery. Numerous old plaques were seen in the periventricular regions, in the corpus callosum and in the left middle cerebellar peduncle. The third case, a 60 year old @entity1 with @entity4794 , presented with @entity9326 and transient @entity1269 . She died 5 years later. Brain examination showed @entity1188 involving both middle cerebral artery territories. There was also many old plaques in the periventricular areas, thalamus, internal capsule, centrum semi-ovale, brain stem and right nucleus dentatus. In the 3 cases, the optic tracts were normal. The spinal cord, examined only in the first case, was also normal. The asymptomatic character of these @entity15 cases can be explained first by the location of the plaques and the lack of spinal cord and optic tract involvement. It could also be due to the small size of the plaques and to axonal preservation. Such features are rare since our 3 observations have been selected from a pathological collection of 125 @entity15 cases and 9,300 general neuropathological records. Six other cases have been previously reported by other authors.
