Endoscopic mucosal resection for advanced non-polypoid XXXX and early stage carcinoma.

@entity1 @entity548 @entity5 @entity14 @entity652 @entity420 @entity2513
PURPOSE: Endoscopic mucosal resection (EMR) techniques were evaluated in the treatment of flat and sessile @entity14 . @entity1 AND METHODS: Fifty-seven @entity1 (32 female, 25 male) with non-polypoid colorectal lesions (n = 71, size >or= 10 mm) were included in the study. @entity5 location, shape, size, and depth (in @entity5 ) were determined by endoscopy and endoscopic ultrasound. EMR was performed using snare resection, endoscopic aspiration mucosectomy, or EMR using a cap-fitted endoscope. RESULTS: Lesion size ranged from 10 to 50 mm. Complete resection was achieved in 59 of 61 benign and 6 of 8 @entity5 . Thirty-five @entity5 were excised in one segment and 34 @entity5 in piecemeal technique. Pathological examination of @entity5 treated by EMR showed @entity652 in 61 and @entity5 in 8 cases. Because of the non-lifting sign, 2 of 71 @entity5 were not treated endoscopically and referred to surgical resection revealing a T2 @entity420 in both cases. Resection was incomplete in 2 of 61 @entity652 with histological positive resection margin. Complications occurred in 2 @entity1 , with 1 @entity548 treated endoscopically and 1 perforation treated by surgery. Local recurrence was observed in 2 of 59 completely resected @entity652 and in none of 6 @entity5 during a mean follow-up of 18 months (range 6 to 30 months). CONCLUSION: Advanced non-polypoid @entity2513 and @entity5 can be safely and effectively resected by endoscopic mucosal resection.
