Extracapsular invasion of sentinel lymph nodes is not associated with disease recurrence in XXXX .

@entity1 @entity0 @entity4298
Abstract The purpose of this study was to evaluate the presence of extracapsular invasion (ECI) in positive sentinel lymph nodes (SLNs) as a predictor of disease recurrence in @entity0 . @entity4298 biopsy was performed on 318 breasts of 316 @entity0 @entity1 , of which 50 (15.7%) had positive SLNs. Six (12.0%) of these 50 cases had disease recurrence. The clinicopathologic features of these cases were reviewed. The ECI at SLNs was not significantly associated with disease recurrence. The recurrence-free interval by Kaplan-Meier curves did not differ significantly among @entity1 with and without ECI at SLNs. On the other hand, metastasis at non-SLNs was observed in 12 cases (24.0%) among the 50 cases with positive SLNs, and in the non- @entity4298 metastasis group there were 7 @entity1 with ECI at non-SLNs. Three of 7 cases with ECI at non-SLNs had disease recurrence and none of those 5 without ECI at non-SLNs had disease recurrence. Our current study suggests that the presence of ECI at metastatic SLNs is not associated with recurrent disease in @entity0 . Our results also imply that @entity1 with ECI at positive non-SLNs have a high risk of disease recurrence.
