Serologic diagnosis of XXXX in experimentally infected pregnant @entity1237 and transplacentally infected kids.

@entity3252 @entity1237 @entity3204
Eight pregnant @entity1237 were inoculated orally with 10 to 1,000 oocysts of @entity3204 at 83 to 102 days of gestation. Serum samples from the @entity1237 and from the kids born to them were analyzed, using the Sabin-Feldman dye test (DT), a commercially available modified agglutination test (MAT), and a latex agglutination test. Six of the does were observed for greater than 1 year; during this time, they delivered twice. All does developed DT and MAT antibody titers of greater than or equal to 1:2,048 within 29 days after inoculation, and the high titers persisted through the 2nd pregnancy; therefore, serologic results alone should not be relied on for the diagnosis of @entity3204 -induced abortion in does. On the other hand, all transplacentally infected kids had DT or MAT antibody titers of 1:2,048 before ingesting colostrum, indicating the usefulness of serologic evaluation of the fetus or stillborn kid in the diagnosis of abortion. Antibody was not found in the sera of noninfected kids born to @entity3204 -infected does. The passively acquired colostral antibody declined by 5 months. Therefore, specific antibody found in adult @entity1237 is probably actively acquired. The commercially available MAT was simple, sensitive, and reliable for the diagnosis of caprine @entity3252 . The latex agglutination test needs further improvement, as titers rarely exceeded 1:256.
