Localized malignant @entity2615 of the epithelial type occurring as a primary XXXX : a case report with review of the literature.

@entity1326 @entity5 @entity2269 @entity2615 @entity1325 @entity876 @entity3558 @entity2280 @entity99
We report a localized malignant @entity2615 of the epithelial type, occurring as a primary @entity99 in a 64-year-old male. He was found to have a mass located in the right lobe of the liver. Surgery was carried out with resection of the mass from the right hepatic lobe, with partial resection of the diaphragm. Grossly, an ill-defined @entity5 was present in the @entity99 . Histologically, the @entity5 displayed a predominant tubular pattern of growth with a @entity2269 . The tubules were lined by a single layer of cuboidal or flattened cells with pleomorphic vesicular nuclei. A hyaluronidase-digestible, @entity3558 -like substance was demonstrated in the lumen and @entity5 cytoplasm. The @entity5 cells were immunohistochemically positive for calretinin, HBME-1, cytokeratin, i.e. @entity1325 / @entity1326 and CAM 5.2, but negative for carcinoembryonic antigen, @entity2280 and Leu M1. Moreover, the @entity5 cells showed nuclear accumulation of the @entity876 oncopotein and reacted frequently with Ki-67 antibody. These findings support the concept that malignant @entity2615 of the epithelial type may occur at extrapleural sites. To the best of our knowledge, this is the first reported case of localized malignant primary @entity2615 arising in the liver.
