XXXX : An Update on Treatment Outcomes and Prognostic Factors from the National Cancer Data Base (NCDB).

@entity1 @entity3243 @entity5
BACKGROUND: @entity3243 is a rare disease. Conflicting results on prognostic factors and extent of surgical resection for @entity1 with @entity3243 have been made based on small sample sizes. A large, robust dataset is needed to help address some of the controversies. METHODS: A retrospective review of @entity1 with @entity3243 in the National Cancer Data Base from 1985 to 2006 was performed. Characteristics of the cohort and type of treatment were evaluated. Prognostic factors were assessed with Cox proportional hazards regression models and 5- and 10-year OS rates were determined. RESULTS: There were 733 evaluable @entity1 with a mean age of 56.1      15.3  years (median 57, range 15-89) and mean @entity5 size of 29.6      18.4  mm (median 25.0  mm, range 10.0-150.0). @entity5 size, age at diagnosis, male sex, positive nodal status, and complete @entity5 resection had hazard ratios for death of 1.02 (1.01-1.02, p  <  0.0001), 1.06 (1.05-1.07, p  <  0.0001), 1.67 (1.24-2.25, p  =  0.0008), 1.25 (0.57-2.76, p  =  0.6), and 0.42 (0.22-0.81, p  =  0.01), respectively, on multivariable analysis. @entity1 who had removal of the @entity3243 with concomitant resection of adjacent organs had HR for death of 0.70 (0.35-1.41, p  =  0.3). The 5- and 10-year OS rates were 82.3 and 66  % respectively. CONCLUSIONS: @entity1 age, @entity5 size, and sex have modest effects on survival in @entity1 with @entity3243 . A staging system with prognostic value for @entity3243 should include at least these pertinent prognostic factors.
