[Protein loss in XXXX @entity1 during continuous veno-venous hemofiltration].

@entity1 @entity1597 @entity788 @entity295 @entity3124 @entity810 @entity393
OBJECTIVE: To evaluate @entity393 in @entity3124 @entity1 with @entity810 during continuous veno-venous hemofiltration (CVVH) and analysis the major factor impacting protein clearance. METHODS: A analysis was carried out in eighteen (twelve male and six female) @entity295 or severe acute @entity788 @entity1 with @entity810 from September 2008 to September 2009. The average age was 45 years (39 - 62 years). CVVH was conducted for 24 h in all @entity1 . Effluent volume, blood speed, ultrafiltration rate and transmembrane pressure ( @entity1597 ) were 4000 ml/h, (277    89) ml/h, (179    4) ml/min and (173    48) mm Hg (1 mm Hg = 0.133 kPa) respectively. Blood samples were collected before and after filtration in order to detect protein concentration. Ultrafiltrate was obtained hourly to measure protein concentration and calculate @entity393 during session. RESULTS: Mean protein concentration was (231    67) mg/L and @entity393 was (22    6) g/d in ultrafiltrate samples. The difference in serum protein level during hemofiltration was not significant [(56    6) g/L vs. (55    10) g/L, P > 0.05], while there was a weak, but statistically significant correlation between the ultrafiltrate protein concentration and the corresponding value for serum protein (r = 0.481, P < 0.05). However, there was a strong and statistically significant correlation between the ultrafiltrate protein concentration and the @entity1597 (r = 0.564, P < 0.01). Stepwise multiple regression analysis showed that @entity1597 and serum protein concentration played a pivotal role in ultrafiltrate @entity393 . CONCLUSIONS: In addition to renal replacement therapy, serum protein would be cleared through hemofilter during CVVH. @entity1597 and serum protein concentration are the main factors that affect @entity393 in ultrafiltrate. As a result, it is necessary to take account of the @entity393 in ultrafiltrate when setting nutritional schedule.
