Clinical characteristics of potential kidney donors with asymptomatic XXXX .

@entity1 @entity8 @entity101 @entity28 @entity19372 @entity2741 @entity740 @entity5886 @entity1290 @entity5052 @entity209
BACKGROUND: @entity1 with symptomatic @entity1290 are characterized by older age, male gender, white race, @entity101 , @entity28 , @entity209 and @entity740 . Whether these characteristics differ in @entity1 with asymptomatic @entity1290 is unknown. METHODS: All potential kidney donors who underwent protocol computed tomography angiograms/urograms (2000-08) at the Mayo Clinic were identified. @entity8 , including @entity1290 , were assessed radiographically. Comorbidities, including past symptomatic @entity1290 , were abstracted from the medical record. Characteristics of @entity1 with and without radiographic stones were compared. Stone burden among @entity1 with and without past symptomatic stones was compared. RESULTS: Among 1957 potential kidney donors, 3% had past symptomatic stones and 11% had radiographic stones (10% had only asymptomatic radiographic stones). Asymptomatic stone formers were more likely to be of white race, have low urine volumes and have radiographic findings of renal parenchymal thinning, focal @entity8 , @entity19372 and @entity8 . Asymptomatic stone formers were not characterized by older age, male gender, @entity101 , @entity28 , @entity209 , @entity8 , @entity5052 , @entity2741 or @entity5886 . Among @entity1 with radiographic stones, those with past symptomatic stones had a slightly higher number of stones (mean 2.7 versus 2.4; P = 0.04), but a much greater diameter for the largest stone (mean 4.8 versus 1.6 mm; P < 0.001). CONCLUSIONS: Asymptomatic kidney stone formers have different demographic characteristics and many lack the comorbidities that have been described in @entity1 with symptomatic @entity1290 . These findings suggest that different pathophysiologic mechanisms could be involved in asymptomatic stone formation versus symptomatic stone passage.
