Carcinoembryonic-like substance in breast fluid discharge in benign and malignant breast disease and in milk of lactating XXXX .

@entity1 @entity5 @entity0 @entity787
In a search for a simple noninvasive test for early detection of @entity0 , radioimmunoassay was used to determine carcinoembryonic ( @entity787 ) levels in the serum and breast fluid of 26 @entity1 presenting with spontaneous breast discharge, and in the serum and milk of 34 postpartum lactating @entity1 . In 54 milk samples from 34 healthy nursing mothers, the mean @entity787 level was 62.6 +/- 49.2 ng/ml (mean +/- SD) (range 5 to 252 ng/ml). The highest levels were found during the first days after delivery. Serum @entity787 levels measured in 18 of the 34 mothers were negative in 12 cases and normal (10 +/- 5.3 ng/ml) in six. No correlation was found between @entity787 levels in milk and those in serum. In the @entity1 with spontaneous breast fluid discharge, @entity787 levels in the breast fluid measured less than 300 ng/ml in 10 cases, 300 to 1,000 ng/ml in 9 cases and greater than 1,000 ng/ml in 7 cases. None of the 19 @entity1 with @entity787 values below 1,000 ng/ml had a @entity5 . Four of the seven @entity1 with the highest @entity787 levels were found to have @entity0 . Serum @entity787 levels were within the normal range in both the malignant and nonmalignant cases. We conclude that @entity787 levels are markedly elevated in breast fluid discharges in nonlactating @entity1 , and that the highest levels may be associated with @entity5 .
