@entity66 in @entity2835 . Association with @entity5705 inhibition as well as altered XXXX esterification.

@entity1 @entity2835 @entity66 @entity5705 @entity9478 @entity755 @entity1442 @entity1675 @entity9477 @entity165
The nature and etiology of plasma @entity66 in @entity1 with varying stages of @entity2835 ( @entity2835 ) were assessed. Two distinct lipoprotein patterns were observed. In @entity1 with early and intermediate histologic stages of @entity2835 , mild elevations of very low density lipoproteins and low density lipoproteins (LDLs), and marked increases in high density lipoproteins (HDLs) were often noted (group 1). In contrast, @entity1 with @entity1442 had marked elevations in LDLs with the presence of lipoprotein-X, and a significant decrease in HDLs (group 2). The lipoprotein pattern in group 1 was characterized by a normal ratio of free @entity165 to total @entity165 , whereas in group 2, this ratio was elevated. In plasma from group 1 @entity1 only spherical micelles were observed on electron microscopy, whereas in plasma from group 2 @entity1 bilayered disks could be seen in LDLs and HDLs. The increase in HDLs observed in group 1 subjects was associated with elevations in @entity9477 , whereas in group 2 subjects only very low amounts of @entity9478 were observed on analytic ultracentrifugation. Mean plasma @entity755 and C-II concentrations were increased in both groups; but @entity1675 and AII values were divergent, with group 1 subjects having elevated values,and group 2 subjects having decreases values. Mean postheparin @entity5705 activity was decreased in both groups of @entity1 with @entity2835 due to the presence of an inhibitor in @entity2835 plasma, while altered @entity165 esterification was only observed in group 2. These data indicate that @entity5705 inhibition may play an important role in the pathogenesis of the @entity66 seen in early and intermediate @entity2835 , and these abnormalities are then further modified by altered @entity165 esterification in @entity1442 .
