@entity3528 of morbid XXXX regresses during weight reduction.

@entity1 @entity353 @entity28 @entity3528 @entity3157 @entity1391 @entity460 @entity141 @entity1718 @entity2742 @entity461
In order to test the relation between @entity28 and the @entity3528 found in markedly overweight subjects, 24 morbidly @entity28 @entity1 were studied before and after a @entity353 of 35.9 kg obtained by a nutritionally adequate, intermittent very-low-calorie diet. Overweight was reduced from 98 +/- 34% to 44 +/- 19%. Serum total @entity460 did not change, but serum ionized @entity460 ( @entity141 ) increased from 1.22 +/- 0.04 mmol/L to 1.25 +/- 0.04 mmol/L (P less than .001). A corresponding fall was observed in serum parathyroid hormone (s- @entity461 ), which decreased from 47.2 +/- 21.7 pmol/L to 35.2 +/- 19.4 pmol/L (P = .01). The change of s- @entity461 was positively associated with the reduction of body weight (r = .50, P less than .05) and with the reduction of overweight (r = .55, P less than .01). Regarding @entity460 binding substances, serum albumin remained low. The initially lowered serum @entity1391 and @entity3157 both rose (P less than .001). Plasma lactate and plasma free @entity1718 (FFAs) decreased (P less than .001). The study supports our hypothesis that the change profile of @entity460 complexing anions in @entity28 interferes with the tubular reabsorption of @entity460 , which in turn lowers serum @entity141 , thus promoting @entity2742 . Along with @entity353 , concentrations of @entity460 complexing anions returns towards normal values and the @entity3528 regresses.
