XXXX and @entity31 : does it change the therapeutic approach?

@entity1 @entity5 @entity254 @entity31 @entity14 @entity694 @entity1141
OBJECTIVE: The aim of this study was to examine the incidence of coexisting @entity14 in @entity31 in a population of @entity1 undergoing ileal pouch anal @entity254 . The frequency of @entity5 in this population, surgical intervention, general outcomes and @entity5 recurrence are described. METHODS: Data on 1850 @entity1 undergoing restorative proctocolectomy from 1983 to 2001 were reviewed. Information was gathered from data in the department's pelvic pouch database, as well as pathology and surgical reports. Follow-up questionnaires routinely sent to @entity1 as part of the database were included in the analysis to determine current functional status. Mean follow-up period was 7.5 years after surgery. RESULTS: Seventy @entity1 had coexisting @entity14 at time of IPAA. 7 (10%) of @entity5 were incidental. Pre-operative duration of disease was 18.6 years. Twenty-six of the @entity5 were @entity5 . The most common form of @entity254 in the @entity5 was mucosectomy, especially in pre-operatively known @entity5 or low lying @entity1141 . Preferred surgical technique for @entity5 in mucosal @entity31 ( @entity31 ) included high ligation of mesenteric vessels with radical colectomy and taped occlusion of the rectum with irrigation of the rectal stump with Turnbull solution prior to mucosectomy. @entity1 with Stage 3 @entity5 received postoperative chemotherapy. Post-operative radiation therapy was not commonly recommended. Five of 70 @entity1 were deceased from metastatic @entity694 ; 55 @entity1 were confirmed alive with good to excellent pouch function with a follow-up range of 1-17 years. CONCLUSION: Restorative proctocolectomy with ileal pouch anal @entity254 is a successful surgical approach for @entity1 with coexisting @entity14 in @entity31 . When the appropriate surgical technique is used in @entity1 with @entity694 , along with adjuvant chemotherapy when appropriate, prognosis and function is very good.
