Acute and chronic diseases as part of multimorbidity in acutely hospitalized older XXXX .

@entity1 @entity712 @entity101 @entity6 @entity548 @entity73 @entity102 @entity810 @entity1030 @entity955 @entity2275
BACKGROUND: To describe the prevalence of multimorbidity and to study the association between acute and @entity102 in acutely hospitalized older @entity1 METHODS: Prospective cohort study conducted between 2006 and 2008 in three teaching hospitals in the Netherlands. 639 @entity1 aged 65years and older, hospitalized for >48h were included. Two physicians scored diseases, using ICD-9 codes. Chronic multimorbidity was defined as the presence of >= 2 @entity102 , and acute multimorbidity as >= 1 acute diseases upon pre-existent @entity102 . Logistic regression analyses were conducted to analyse cluster associations between a chronic index disease and the concurrent chronic or acute disease, corrected for age and sex. RESULTS: The mean age of @entity1 was 78years, over 50% had @entity73 . Prevalence of chronic multimorbidity was 69%, and acute multimorbidity was present in 88%. @entity101 (OR 1.16; 95% CI 1.08-1.24), @entity6 (type I or type 2) (OR 1.12; 95% CI 1.04-1.21), @entity712 (OR 1.25; 95% CI 1.14-1.38) and @entity1030 (OR 1.19; 95% CI 1.05-1.34) were associated with @entity810 . @entity101 (OR 1.10; 95% CI 1.04-1.17) and @entity955 (OR 1.17; 95% CI 1.08-1.27) were associated with an adverse drug event. @entity548 was clustered with @entity955 (OR 1.11; 95% CI 1.04-1.19) and @entity2275 (OR 1.16; 95% CI 1.07-1.25). CONCLUSION: Both acute and chronic multimorbidity was frequently present in hospitalized older @entity1 . We identified specific associations between acute and @entity102 . There is a need for strategies addressing multimorbidity during the exacerbation of @entity102 .
