Comparisons of two intranasal corticosteroid preparations in treating XXXX .

@entity1 @entity2023 @entity5254 @entity4184 @entity5023
OBJECTIVES: Intranasal corticosteroid preparations can relieve symptoms of @entity2023 . Different aqueous corticosteroid forms have been developed for intranasal use. The objectives of this study were to compare efficacy and safety between @entity5023 and @entity4184 in the treatment for @entity1 with @entity2023 . METHODS: The study was conducted in a prospective and randomized manner; a total of 24 adult @entity1 were enrolled. All @entity1 received MAST allergen test at entry and again at 2 months after treatments. Fourteen @entity1 received @entity5023 200 microg once daily, and 10 @entity1 received @entity4184 200 microg twice daily. To investigate the efficacy of @entity5023 and @entity4184 , a subjective scoring system was designed to evaluate the symptom improvement of @entity1 . Adverse events were recorded on a diary card then were analyzed. Mann-Whitney U test and Kruskal-Wallis 1-way analysis of variance were used for statistical analysis. RESULTS: Analysis on @entity1 -based symptom scores revealed that both @entity5023 and @entity4184 were equally efficacious in improving the symptoms of nasal blockage, sneezing, nasal itching, and watery @entity5254 . There were no significant side effects reported for both groups during this follow-up period. However, analysis showed that the @entity5023 group demonstrated significantly greater improvement in some MAST allergen tests (Candida, mite, house dust; P < 0.05). CONCLUSION: Clinically, @entity5023 200 microg once daily was efficacious as @entity4184 200 microg twice daily in the relief of @entity2023 . However, @entity5023 can achieve greater immunologic improvement. Both preparations showed no evidence of short-term side effects.
