Preliminary pharmacological characterization of the XXXX isolated bronchial artery strip: a new preparation.

@entity1169 @entity54881 @entity3858 @entity1421 @entity3045 @entity6310 @entity8765 @entity3044 @entity5015 @entity2647 @entity750 @entity112 @entity1286 @entity3774 @entity3897 @entity34776 @entity291 @entity5402
1 This paper describes a preliminary pharmacological study of the isolated helical strip of @entity291 bronchial artery under isotonic conditions in Krebs-Henseleit solution. 2 The tissue contracted to @entity112 and @entity750 ( @entity750 ), actions which were selectively antagonized by @entity8765 and @entity3858 respectively. @entity112 was not inhibited by @entity54881 and @entity750 was not affected by @entity1286 . 3 Slow reacting substance of anaphylaxis (SRS-A), @entity3774 (PGF2 alpha) and @entity1421 were spasmogenic, whereas @entity5015 caused relaxation. No potential antagonists of these agents were tested. 4 @entity5402 , at all concentrations, caused contractions of the bronchial artery which were completely, irreversibly blocked by @entity3897 . 5 The spasmogenic action of @entity2647 was selectively blocked by @entity34776 . Vessel strips which were partially contracted to @entity112 , relaxed to @entity3044 and @entity3045 . The action of @entity3044 was inhibited similarly by either @entity1169 or @entity6310 . The evidence therefore suggests the presence of functional alpha, beta 1 and beta 2-adrenoceptors.
