Perioperative interstitial irradiation in the conservative management of early XXXX .

@entity1 @entity0 @entity5 @entity4 @entity189 @entity3201
Conservation of the breast in early @entity0 with limited resection and radiation is proving to be as effective as modified radical mastectomy in survival and in loco-regional control. Management at the University of Kansas Medical Center consists of an interstitial implant at the time of lumpectomy to facilitate perioperative irradiation with @entity3201 -192 to the @entity5 bed. An axillary node dissection is also performed at that time. Two to 3 weeks later external beam irradiation is delivered to the entire breast. One hundred and twenty-three breasts in 120 @entity1 have been treated between June 1982 and June 1986. There were 49 pathological Stage I, 63 Stage II, 8 @entity5 , and 3 @entity189 in situ, consisting of 72 T1, 43 T2, 5 T3, and 3 TIS lesions. @entity1 have been followed for a median of 30 months. One @entity1 had a "true" recurrence in the breast. Another @entity1 developed recurrence in a different quadrant. Ninety percent of the @entity1 had good to excellent cosmetic results, 7% were considered fair, and 3% had poor results. Seven @entity1 developed mild @entity4 , 4 were found to have moderate @entity4 , and 1 had severe @entity4 . Our preliminary results indicate that interstitial irradiation immediately after excision results in excellent local control, with very satisfactory cosmesis and no morbidity due to the simultaneous excision and irradiation.
