ENDOPHTHALMITIS CAUSED BY XXXX : Clinical Features, Antibiotic Susceptibilities, and Treatment Outcomes.

@entity1 @entity2892 @entity796 @entity2890 @entity2177 @entity726 @entity4509 @entity5553 @entity3225 @entity5505
PURPOSE: To report the clinical features, antibiotic susceptibilities, and visual outcomes associated with @entity3225 caused by @entity796 . METHODS: A consecutive case series. Microbiology database records were retrospectively reviewed for all @entity1 with @entity3225 caused by @entity796 from January 1, 2002, to December 31, 2012, at a large university referral center. The corresponding clinical records were then reviewed to evaluate the @entity3225 clinical features and treatment outcomes. RESULTS: In the 12 @entity1 identified, clinical settings included postcataract surgery (n = 4), postpenetrating keratoplasty (n = 3), endogenous source (n = 2), post-pars plana vitrectomy (n = 1), trabeculectomy bleb-associated setting (n = 1), and @entity726 drainage implant-associated setting (n = 1). All @entity1 presented with hypopyon. Presenting visual acuity was hand motions or worse in all cases. All isolates were susceptible to @entity5505 and @entity5553 . When comparing isolates in this study with isolates from a previous study (1987 to 2001), the minimal inhibitory concentration required to inhibit 90% of isolates (MIC 90, in micrograms per milliliter) remained the same for @entity5505 (8), @entity2177 (0.5), @entity2892 (4), @entity2890 (0.5), and @entity4509 (4). Initial treatment strategies were vitreous tap and injection (n = 9) and pars plana vitrectomy with intravitreal antibiotics (n = 3). Final visual acuity was light perception or worse in 11 of the 12 @entity1 (92%). Five @entity1 underwent enucleation (42%). CONCLUSION: All isolates were susceptible to @entity5505 and @entity5553 , and all MIC 90s for isolates in the current period compared with isolates from 1987 to 2001 remained identical. Despite early and appropriate treatment, outcomes were generally poor with a high rate of enucleation.
