Survival after first recurrence in XXXX .

@entity1 @entity0
The aim of the present study was to evaluate the significance of primary stage, histopathological grade, disease-free survival and site of first relapse on survival after first recurrence. The study included 1621 female @entity0 @entity1 admitted between 1970 and 1975. The @entity1 material was analysed by unifactorial life table methods and the multifactorial Cox regression analysis. The primary stage and histopathological grade maintained a significant prognostic value also after relapse. Survival after first recurrence was dependent on the disease-free interval and site of first relapse, too. If the disease-free survival was over 5 years, 44% of the @entity1 were still alive after 7 years from recurrence. Of the @entity1 with a disease-free survival shorter than 2 years, only 10% were alive after 7 years from recurrence. Survival was significantly better after locoregional relapse than after distant relapse, but the difference levelled off within 7 years. The prognosis of axillary relapse was best and that of liver and brain metastases poorest. Regression analysis confirmed the importance of primary stage, site of recurrence and histopathological grade as prognostic variables for survival after first recurrence.
