[Physiology of XXXX formation, diurnal fluctuation of intraocular pressure and its significance for @entity726 ].

@entity1 @entity7462 @entity227 @entity726
In the @entity1 eye there is a balance between production of @entity7462 as well as its drainage. The intraocular pressure is held through different mechanisms in a stable balance. The @entity7462 is secreted by the ciliary epithelium lining the ciliary processes. Three physiological processes contribute to the formation and chemical composition of the @entity7462 : diffusion (5 %), ultrafiltration (15 %) and active secretion (80 %). The normal intraocular pressure amounts to 15    3 mmHg, the normal diurnal fluctuation 5 mmHg. @entity7462 leaves the eye by passive bulk flow via two pathways: the trabecular route and the uveoscleral route. In @entity726 @entity1 this balance is disturbed resulting in individual high intraocular pressure or, respectively, high diurnal fluctuations. This leads to loss of @entity227 . As a recommendation for @entity726 @entity1 it is useful to construct diurnal intraocular pressure curves to evaluate the "type of pressure" and to determine the diurnal fluctuations or, respectively, the time of the pressure maxima. With this knowledge, treatment of @entity726 @entity1 can be managed in a more individualised manner and it seems to slow down the progress of the disease better than by merely reducing the intraocular pressure.
