The effects of anterior cruciate ligament lesion on the articular cartilage of growing XXXX .

@entity1 @entity75 @entity1237 @entity130
Treatment of anterior cruciate ligament (ACL) injury in skeletally immature @entity1 is controversial. The growth plate could be damaged if treated with the reconstruction techniques used to treat instability in adults. For this reason, many authors postpone surgical treatment until skeletal maturity, but the acceptable length of time that treatment can be postponed without causing irreversible damage to the articular cartilage in @entity1 with @entity130 is unknown. Until now, no studies have described the pathological findings and the evolution of the lesions of the articular cartilage during the growing period. For this reason, an experimental study on 16 6-month-old, skeletally immature @entity1237 was performed. A complete @entity75 was achieved by removing the ligament. Two animals per group were sacrificed at intervals of 1, 3, 6, and 9 months postoperatively, and macroscopic and microscopic evaluations were performed. The presence of @entity130 and articular cartilage lesions with progressive aspects were histologically underlined. The hystological observations showed that the complete @entity75 causes irreversible articular cartilage alterations in growing @entity1237 3 months after injury. These experimental data suggest that ACL reconstruction in growing @entity1 with @entity130 and instability should be indicated without waiting until skeletal maturity.
