Genetic advantageous predisposition of angiotensin converting enzyme id polymorphism in Tunisian XXXX .

@entity2587 @entity1 @entity1289
BACKGROUND: ID polymorphism of the gene coding for the @entity1289 ( @entity1289 ) represents a determining factor in physical and athletic performance in the context of genetic conditioning of sports predisposition. The aim of this study was to show the potential importance of genetic factors in relation to the athletic status in Tunisian @entity2587 . METHODS: The @entity1289 genotypes were established using polymerase chain reaction (PCR) amplification for 282 Tunisian @entity2587 (endurance: N.=149 - power: N.=133), and 211 sedentary volunteers. RESULTS: No significant difference was found in the @entity1289 genotype distribution between @entity2587 (36% DD, 49% ID, 15% II) and controls (CTR) (39% DD, 46% ID, 15% II; P=0.72). In contrast, a high significant difference between endurance and power groups were noted in genotype and alleles (  2=10.32, P=0.0057;   2=4,752, P=0.029, respectively). The elite endurance- @entity2587 (N.=72) possess some inherent genetic advantage predisposing them to superior athletic performances compared to CTR for @entity1289 alleles (  2=3.51, P=0.06). In addition endurance trained @entity2587 were also significantly different from CTR for @entity1289 genotype (  2=6.05, P=0.04). Furthermore, a significant difference have been found between elite power- @entity2587 (N.=59) and CTR for @entity1289 alleles (  2=3.79, P=0.05). CONCLUSIONS: Tunisian @entity2587 exhibit insertion (I) and deletion (D) alleles of the @entity1289 polymorphism associated with a high level of @entity1 endurance and power performance, respectively. This genetic background plays an important role in sporting potential and causes some individuals to be better adapted to specific physical training. This should be considered in athlete development to identify which sporting specialties should be trained for Tunisian talent promotion.
