Prognostic parameters in XXXX of the uterus: a clinico-pathologic study.

@entity1 @entity1204 @entity3038 @entity66 @entity5 @entity74 @entity3 @entity6962
BACKGROUND: @entity6962 of the uterus are highly aggressive @entity5 with early lymphatic and hematogenous spread. The most important prognostic factor in @entity6962 is the extent of the @entity5 at the time of diagnosis. The prognostic impact of other factors such as @entity3 , menopausal age, age, parity and adjuvant therapy is still being discussed controversially. MATERIALS AND METHODS: Nineteen @entity1 with histologically proven @entity6962 were included in the analysis. The @entity1 were staged according to a modification of the International Federation of Gynecology and Obstetrics (FIGO) staging system for @entity1204 . For each @entity1 , the histological material was reviewed by an experienced pathologist. @entity6962 was defined histologically as any @entity5 of uterine origin composed of @entity3038 . RESULTS: The median follow-up time was 91 months (25% quartile, 47 months; 75% quartile, 145 months). The median overall survival of the 19 @entity1 was 59 months, resulting in a 5-year overall survival rate of 43%. Three out of the nineteen (16%) @entity1 @entity74 while 6 out of 10 (32%) @entity1 developed @entity66 with a median disease free survival of 16 months (range 8-54). Eleven out of nineteen (58%) @entity1 died of the disease. A univariate model revealed that early @entity5 stage (stage 1) (p<0.023), low @entity3 (p<0.017) and late onset of the menopause (p<0.050) were significantly associated with a lengthened overall survival in @entity1 with @entity6962 . Age (p=0.34), parity (p=0.16) and adjuvant radiotherapy (p=0.45) did not influence overall survival of @entity1 with @entity6962 . CONCLUSION: Early @entity5 stage, low @entity3 and late onset of the menopause are associated with a lengthened overall survival in @entity1 with @entity6962 .
