Metrics to assess quality of life after management of XXXX .

@entity1 @entity2 @entity5
Quality of life (QOL) is a key clinical outcome in @entity1 with @entity2 because of the debilitating nature of the disease and its treatments. In recent years, advances have been made in the assessment of QOL via @entity1 -reported outcomes. A brief history of the evolution of QOL measures in oncology clinical trials and practice is given with specific reference to @entity5 . The role that QOL can play as a prognostic factor, especially among @entity2 @entity1 , is delineated. The most commonly seen symptoms among @entity2 @entity1 are listed. This review is intended to provide the clinical researcher with a summary of the alternative measures that are both valid and reasonable to consider when assessing QOL in @entity5 @entity1 . Suggestions for QOL assessment in both a research setting and clinical environment are considered. A review of the most popular QOL assessments in general application to @entity2 and disease-specific measures is provided. An algorithm for selecting appropriate QOL assessments for @entity2 clinical research is provided. The primary conclusion from this work is that scientifically sound investigations into the QOL of @entity5 @entity1 are feasible and encouraged so that the care of these @entity1 can be optimized.
