Predictors of @entity24103 in @entity1 who have sex with XXXX with benign cytology.

@entity1 @entity75 @entity3538 @entity24103 @entity6349 @entity1141
PURPOSE: Anal cytology is used to screen @entity1 for @entity24103 . Anal pap smears are collected without direct visualization of the canal, whereas cervical cytology is obtained with direct visualization. Current screening guidelines dictate that @entity1 with abnormal cytology are to be evaluated with high-resolution anoscopy, and @entity1 with benign anal cytology forgo high-resolution anoscopy. We routinely perform standard anoscopy after cytology collection. We endeavored to determine whether our standard procedure would reveal findings supporting high-resolution anoscopy even with benign cytology. METHODS: We performed a retrospective chart review of all anal cytology results from January 2008 to March 2009, identifying the @entity1 with benign results who had undergone high-resolution anoscopy. Records were analyzed to determine the indication for high-resolution anoscopy and biopsy results. RESULTS: We identified 2084 @entity1 with anal cytology results, including 613 (29%) @entity1 who had benign results and 169 (28%) @entity1 who had undergone high-resolution anoscopy. The main reasons for high-resolution anoscopy were high risk of recurrent @entity1141 based on prior high-grade squamous @entity75 with cytology done concurrently in 77 (46%), and abnormal anoscopy findings thought to be indicative of @entity1141 (plaque or nodule suspicious of @entity1141 , @entity3538 , @entity6349 appearing fissure) in 92 (54%). Of subjects with abnormal anoscopy findings indicative of @entity1141 , 25 (27%) had high-grade and 39 (42%) had low-grade @entity1141 . Of those undergoing cytology and high-resolution anoscopy simultaneously, 14 (18%) had high-grade and 12 (16%) had low-grade @entity1141 . In total, 90 (53%) of those with benign cytology who had high-resolution anoscopy had abnormal pathology, and 39 (23%) had high-grade @entity1141 . CONCLUSIONS: @entity1 having sex with @entity1 can have significant @entity1141 with benign cytology. Standard anoscopy identifies findings indicative of @entity1141 that, if present, should lead to high-resolution anoscopy even with benign cytology. Standard anoscopy should become an integral part of @entity24103 screening. Prior recent history of high-grade @entity1141 should lead to high-resolution anoscopy even with benign cytology.
