Uterine expression of @entity30506 family during the course of pregnancy in XXXX .

@entity1707 @entity227 @entity71636 @entity73089 @entity36931 @entity73090 @entity46280 @entity141 @entity30506
To stably maintain pregnancy, several genes are expressed in the uterus. In particular, the endometrial expression of genes encoding growth factors appears to play a key role in maternal-foetal communication. The previous studies characterized the endometrial expression kinetics of the genes encoding @entity30506 ( @entity30506 ), its receptor ( @entity46280 ), @entity73089 ( @entity73089 ), @entity71636 ( @entity71636 ), @entity73090 and @entity36931 (CaBP-9k) in @entity1707 during implantation. Here, we further characterized the expression patterns of these molecules during the entire porcine pregnancy. Porcine uteri were collected at @entity227 ( @entity227 ) 12, 15, 30, 60, 90 and 110 and subjected to RT-PCR. @entity30506 and @entity46280 showed similar expression patterns, being highly expressed around implantation and then disappearing. @entity73089 and @entity71636 expression levels rose steadily until they peaked at PD30, after which they gradually decreased to PD12 levels. This @entity71636 mRNA expression pattern was confirmed by real-time PCR and similar @entity71636 protein expression patterns were observed. Immunohistochemical analysis of PD60 uteri revealed @entity71636 in the glandular and luminal epithelial cells. @entity73090 was steadily expressed throughout the entire pregnancy, while CaBP-9k was expressed strongly on PD12, and then declined sharply on PD15 before recovering slightly for the remainder of the pregnancy. Thus, the @entity30506 family may play a key role during implantation in @entity1707 . In addition, CaBP-9k may help to maintain uterine quiescence during pregnancy by sequestering cytoplasmic @entity141 .
