The cadherin-catenin complex in XXXX .

@entity1 @entity5 @entity1711 @entity5962 @entity189 @entity3546 @entity1710 @entity3
Abnormal Wnt signaling and impaired cell-cell adhesion due to abnormal @entity5962 and @entity3546 function have been implicated in many @entity5 , but have not been fully explored in @entity189 . The aim of this study was to analyze @entity3546 cellular location and @entity5962 expression levels in @entity189 . @entity5962 expression levels were also correlated with clinical data and underlying pathology. @entity3546 and @entity5962 expression were examined in 18 @entity189 and 7 non-tumoral inflammatory pharynx tissues using immunohistochemical methods. @entity1 clinical data were collected, and histological evaluation was performed by @entity1710 / @entity1711 staining. @entity3546 was detected in membrane and cytoplasm in all cases of @entity189 , regardless of histological type; in non-tumoral tissues, however, @entity3546 was observed only in the membrane. As for @entity5962 expression levels, strong staining was observed in most non-tumoral tissues, but staining was only moderate in @entity189 tissues. @entity5962 expression was associated with @entity3546 localization, study group, @entity3 , and @entity1 outcomes. Reduced levels of @entity5962 protein observed in nasopharyngeal carinoma may play an important role in invasion and @entity3 . Cytoplasmic @entity3546 in @entity189 may impair cell-cell adhesion, promoting invasive behavior and a @entity3 phenotype.
