Tracking down the footprints of bad paternal relationships in XXXX : A diffusion tensor imaging study.

@entity1 @entity4785 @entity130
UNASSIGNED: Preclinical studies indicate that stress early in life can cause long-term alterations in brain development. Studies have shown alterations in the brain functions of @entity1 after experiencing @entity130 . Our aim is to examine whether the integrity of white matter tracts might be affected in @entity4785 ( @entity4785 ) @entity1 . A total of 15 @entity4785 @entity1 and 15 healthy controls were studied, with the groups matched by age and gender. Diffusion-weighted echoplanar brain images were obtained using a 1.5 Tesla magnetic resonance imaging scanner. Regions of interest were manually placed on directional maps based on principal anisotropy. Apparent diffusion coefficient and fractional anisotropy (FA) values of white matter were measured bilaterally in the anterior corona radiata (ACR) and by diffusion tensor imaging in the genu and splenium of the corpus callosum. Significantly lower FA values were observed in the right ACR of @entity4785 @entity1 versus healthy individuals. We also found an association between bad paternal relationships and lower FA in the genu of the corpus callosum in female @entity1 . Alterations in the right ACR suggest that diffusion anisotropy measurement can be used as a quantitative biomarker for @entity4785 . Paternal relationships may also affect the brain's microstructure in @entity1 with @entity4785 .
