Productivity outcomes following endoscopic sinus surgery for XXXX .

@entity1 @entity697 @entity73 @entity228 @entity1412
OBJECTIVES/HYPOTHESIS: We sought to evaluate preoperative and postoperative productivity losses and quality of life (QOL) impairment reported by @entity1 with @entity697 ( @entity697 ) as compared to @entity1 with chronic rhinosinusitis without @entity1412 (CRSsNP). STUDY DESIGN: Prospective, multi-institutional, nested case-control. METHODS: @entity1 with @entity697 (n = 20) and CRSsNP (n = 20) undergoing endoscopic sinus surgery (ESS) were enrolled as part of a prospective cohort study. For comparison, @entity1 diagnosed with @entity697 cases were age/gender-matched to control @entity1 diagnosed with CRSsNP using a 1:1 ratio. RESULTS: @entity697 and CRSsNP @entity1 were followed for    14 months postoperatively. Productivity losses were reported as the number of days missed from normal productive activities out of the previous 90 days. @entity697 @entity1 reported similar baseline productivity losses (12.6    27.1 [standard deviation]) as @entity1 with CRSsNP (11.7    20.9; P = .314). Postoperatively, improvement in productivity losses was similar between @entity697 @entity1 and CRSsNP controls (-6.7    20.0 vs. -9.8    19.1; P = .253). Preoperative and postoperative disease-specific QOL measures (Sino-Nasal Outcomes Test-22 and Rhinosinusitis Disability Index) were similar between the two groups. @entity697 @entity1 reported a significant decrease in days of previous antibiotic (P = .009) and nasal decongestant (P = .004) use following ESS, whereas @entity1 with CRSsNP reported a significant decrease in antibiotic (P = .002) and oral @entity228 use (P = .002). CONCLUSIONS: @entity697 @entity1 report baseline productivity losses and disease-specific @entity73 to levels that parallel those with CRSsNP. @entity1 with @entity697 report improvement in QOL following ESS in all disease-specific QOL measures and in several medication measures. Productivity losses and postoperative improvements are similar between @entity1 with @entity697 and CRSsNP. LEVEL OF EVIDENCE: 3b Laryngoscope, 126:1046-1053, 2016.
