The XXXX : a survey of the Prognostic Inflammatory and Nutritional Index (PINI) in advanced disease.

@entity1 @entity353 @entity5 @entity3124 @entity130
Other than @entity353 , most traditional methods of nutritional assessment are not acceptable in advanced @entity5 @entity1 because they are inaccurate, too expensive for routine use, or too difficult for a debilitated @entity1 to complete. The prognostic inflammatory and nutritional index (PINI) is a formula devised to evaluate nutritional status and prognosis in @entity3124 @entity1 . It has been suggested that the PINI score can be used to follow most pathological conditions. It has been measured in several settings and has been found to be a reliable indicator of both nutritional status and prognosis in @entity130 , burn, infected, and cardiac @entity1 . In this pilot study, we evaluated the PINI in 50 consecutive @entity1 referred to a palliative care service. Compared to a value in normal, healthy @entity1 of <1, the mean score in this sample was 102 (SD = 142, 95% CI = 62-142). The mean protein values were: alpha-1-acid glycoprotein 1409 mg/l (SD = 556, 95% CI = 1251-1567); C-reactive protein (CRP) 106 mg/l (SD = 89, 95% CI = 81-131); albumin 24 g/l (SD = 7, 95% CI = 23-26); and prealbumin 147 mg/l (SD = 73, 95% CI = 126-168). There was no significant association between the PINI and corticosteroid use, @entity353 over time, age, or sex. These data indicate that the PINI is highly abnormal in our population. The CRP may be the most important value.
