Usefulness of the Exhaled Breath Temperature Plateau in Asthma XXXX .

@entity1 @entity32 @entity2488 @entity565 @entity842
BACKGROUND: Exhaled breath temperature (EBT) has recently been proposed as a noninvasive marker of @entity32 in @entity1 with @entity565 . However, the usefulness of EBT in everyday clinical practice is not well established. Results to date are contradictory and are mainly derived from small, pediatric populations. A comparison of results is further complicated by the use of different equipment and measurements. OBJECTIVE: We performed a comprehensive study to determine whether EBT is related to @entity565 control, disease severity, @entity2488 . METHODS: Sixty-nine @entity1 on maintenance treatment for @entity565 were included in a cross-sectional study. At the same visit, we measured the EBT plateau (EBTp) using an X-halo Breath Thermometer (Delmedica, Singapore), the fraction of exhaled @entity842 (FeNO), spirometry, and inflammatory cell count in induced sputum, and we administered the Asthma Control Test questionnaire. RESULTS: No significant differences were found between EBTp measurements and the level of @entity565 control, disease severity, @entity2488 , FeNO levels, or inflammatory @entity565 phenotypes. We found a significant difference between EBTp and gender. The EBTp was 34.07  C (SD 0.74) in @entity1 and 34.38  C (0.46) in @entity1 (p = 0.038). We also found a significant correlation between EBTp measurements and the induced sputum eosinophil count (R = -0.348, p = 0.003). CONCLUSIONS: The results of this study do not support the usefulness of the EBTp in @entity565 management in routine clinical practice. Further research using standardized methods is needed to determine the potential use of the EBTp measurement in @entity565 management.    2015 S. Karger AG, Basel.
