Clinical, polysomnographic, and CPAP titration features of XXXX : Mixed versus purely obstructive type.

@entity1 @entity387 @entity28 @entity27 @entity25 @entity386
PURPOSE: To determine whether @entity27 ( @entity27 ) @entity1 with @entity387 ( @entity387 ) have different clinical, polysomnographic, and continuous positive airway pressure (CPAP) titration findings compared to @entity27 @entity1 without @entity387 . METHODS: We retrospectively reviewed the records of @entity27 @entity1 who had undergone CPAP titration and categorized them into pure-OSA and mixed-OSA groups. Demographic features, @entity25 , and @entity386 severity were compared between the two groups using univariate and multivariate analyses. CPAP titration findings were also compared between the two groups. RESULTS: One hundred and ninety-five subjects (n=126 pure-OSA; n=69 mixed-OSA) were included in the analysis. Compared to the pure-OSA group, the mixed-OSA group had a higher percentage of males (p=0.003) and a higher body mass index (p=0.044), Epworth Sleepiness Scale score (p=0.028), and @entity27 index (AHI) (p<0.001). In logistic regression analysis, older age, male sex, and higher body mass index were independently associated with mixed-OSA before PSG study. When using AHI as a covariable, the higher AHI with older age, male sex, and @entity25 was independently related to mixed-OSA. The mixed-OSA group had a higher percentage of @entity1 with @entity387 , a lower percentage of @entity1 with optimal titration, and a higher titrated pressure than the pure-OSA group. CONCLUSIONS: Severe OSA, older age, male sex, @entity28 , and @entity25 were related to mixed-OSA. @entity387 , less optimal titration, and a higher titrated CPAP were also associated with @entity387 in @entity27 @entity1 .
