Local thrombolytic therapy in severe XXXX during puerperium.

@entity1 @entity715 @entity16 @entity50
This study is to explore and evaluate the efficacy and safety of local thrombolytic therapy in superior sagittal sinus in @entity1 with severe @entity50 during puerperium, as well as the efficacy and safety of anti-platelet aggregation treatment for preventing recurrence. Twelve @entity1 during postpartum period with @entity50 were received local thrombolytic therapy by placing a micro-catheter at the distal end of superior sagittal sinus from January 2008 to December 2013. All the @entity1 accepted mechanical @entity715 maceration before local intrasinus thrombolytic therapy, and were treated with low molecular weight heparin in the acute phase. After local thrombolytic therapy, anti-platelet aggregation treatment was performed for 6 months. Follow-up data included lumber puncture, fundus examination and magnetic resonance venography (MRV) once per half year for 6-70 months. At discharge, the intracranial pressure of 12 @entity1 reduced to below 200 mmH2O. DSA or MRV confirmed that superior sagittal sinus of 9 @entity1 were smooth. The cortex venous and deep venous were recovered to normal. Superior sagittal sinus of 3 @entity1 recanalized partly. Cortex venous and deep venous was compensated. The follow-up study indicated that no @entity715 and new @entity16 occurred among all @entity1 . Local thrombolytic treatment is safe and effective in @entity1 with severe @entity50 during puerperium. The collateral circulation compensation is the main recovery factor. And it is also safe and effective for anti-platelet aggregation treatment to prevent recurrence of @entity50 .
