XXXX : a controversial lesion.

@entity1 @entity2803 @entity8 @entity1986
Seven autopsies performed on immunosuppressed bone marrow transplant recipients who died with documented herpes virus infection were reviewed. The kidneys were studied by light and electron microscopy and revealed no pathological findings, specifically no @entity8 or tubular @entity1986 . Seven renal biopsies performed on kidney transplant recipients in whom a diagnosis of @entity8 was entertained were also studied. These @entity1 exhibited clinical parameters suggestive of @entity2803 . Three @entity1 had subsequent nephrectomies and two showed severe acute vascular rejection. The one kidney without demonstrable acute vascular rejection was negative for cytomegalovirus on culture. Three additional @entity1 improved or stabilized their renal function under therapy for rejection. Light, electron microscopic and immunofluorescent studies, although confirmatory of endothelial cell damage, did not substantiate active @entity8 in these @entity1 . An additional group of fifteen @entity1 with disseminated @entity2803 revealed no evidence of @entity8 . Finally, two kidney transplant recipients with proven @entity2803 (one with associated tubular @entity1986 ) also showed no glomerular alterations. It is the author's opinion that the entity that has been considered as @entity8 probably represents rejection, either a peculiar anti-endothelial type of rejection or a protracted, early, or partially resolved acute vascular rejection without residual or identifiable acute vascular rejection changes in the tissue sampled.
