The effect of soy food intake on mineral status in premenopausal XXXX .

@entity1 @entity417 @entity4409 @entity219 @entity69 @entity1955 @entity102 @entity8282 @entity6400 @entity68
BACKGROUND: Soy foods have been substituted for meat in recent years because of proposed health benefits. Research indicates, however, that soy protein and phytate in soy products inhibit the absorption of divalent cations. METHODS: Our study was primarily designed to determine the effect of consuming two to three servings per day of soy foods, providing    19   g protein and    36   mg @entity6400 , on @entity68 and @entity219 status in premenopausal @entity1 during a 10-weeks period. As secondary outcomes, we also tested the effect of soy foods on biochemical markers of bone and thyroid hormones. Nonsmoking @entity1 (18-28 years) without @entity102 , @entity417 , pregnancy, or irregular menstrual cycles were randomly assigned to either the soy food (SF, n=31) or @entity4409 ( @entity4409 , n=32) group. Blood and urine samples and 3-day dietary records were collected at baseline and postintervention. RESULTS: At baseline, @entity68 and @entity219 status, bone markers, and thyroid hormones were not different between groups. After intervention, no significant changes were observed in hemoglobin, @entity69 saturation, serum @entity68 , ferritin, or @entity8282 ( @entity8282 ) concentrations. Plasma @entity219 , but not serum alkaline phosphatase, significantly decreased in both groups (-0.8    mol/L). The change in bone-specific alkaline phosphatase was significant between SF (1.5   U/L) and @entity4409 (-0.7   U/L) groups. No significant changes were observed in bone resorption, thyroid-stimulating hormone (TSH), or free @entity1955 after soy food intake. CONCLUSIONS: Incorporating    19   g soy protein from soy foods for 10 weeks had no significant effect on @entity68 or @entity219 status, bone resorption or formation, or thyroid hormone status in premenopausal @entity1 .
