Success Factors of Laparoscopic Nerve-sparing Radical Hysterectomy for Preserving Bladder Function in @entity1 with XXXX : A Protocol-Based Prospective Cohort Study.

@entity1 @entity1494 @entity5 @entity128 @entity3846 @entity3847
BACKGROUND: Success factors of laparoscopic nerve-sparing radical hysterectomy (LNRH) to preserve @entity1494 are little known despite its widespread use. Thus, we conducted a protocol-based prospective cohort study to evaluate clinicopathologic factors for preserving autonomic nerves and its impact on duration of postoperative catheterization (DPC). METHODS: From 2012 to 2014, 30 @entity1 with stage @entity3846 to IIA2 cervical @entity5 were recruited prospectively to undergo LNRH. All procedures were performed on the left side of the @entity1 by one gynecologic oncologist. Extent of resection and preservation of autonomic nerves were documented in the protocol during LNRH. RESULTS: All @entity1 received laparoscopic type C1 radical hysterectomy, where extent of resection and preservation of autonomic nerves were not different between the right and left sides. Stage @entity3846 disease was associated with the reduced risk of @entity128 ; between the splanchnic nerve and the vesical branch of the pelvic plexus (S-V junction) (adjusted odds ratios, 0.06 and 0.06; 95  % confidence intervals, 0.01-0.92 and 0.01-0.48); the right S-V junction with marginal significance (adjusted odds ratio, 0.18; 95  % confidence interval, 0.03-1.06). Furthermore, bilateral preservation of autonomic nerves decreased DPC significantly when compared with failure or unilateral preservation (median, 6  days vs. 34  days or 57  days; P  <  0.05). CONCLUSIONS: LNRH has a higher likelihood of its success in stage @entity3846 than in stage @entity3847 to IIA disease. Moreover, preservation of bilateral autonomic nerves reduces DPC significantly in comparison with failure or unilateral preservation.
