Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of XXXX .

@entity1 @entity0 @entity5 @entity513 @entity3201
BACKGROUND: Accelerated partial breast irradiation (APBI) may be used to deliver radiation to the @entity5 bed post-lumpectomy in eligible @entity1 with @entity0 . @entity1 and @entity5 characteristics as well as the lumpectomy technique can influence @entity1 eligibility for APBI. This report describes a lumpectomy procedure and examines @entity1 , @entity5 , and surgical characteristics from a prospective, multicenter study of electronic brachytherapy. METHODS: The study enrolled 65 @entity1 of age 45-84 years with @entity513 or @entity513 in situ, and 44 @entity1 , who met the inclusion and exclusion criteria, were treated with APBI using the Axxent   electronic brachytherapy system following lumpectomy. The prescription dose was 34 Gy in 10 fractions over 5 days. RESULTS: The lumpectomy technique as described herein varied by site and @entity1 characteristics. The balloon applicator was implanted by the surgeon (91%) or a radiation oncologist (9%) during or up to 61 days post-lumpectomy (mean 22 days). A lateral approach was most commonly used (59%) for insertion of the applicator followed by an incision site approach in 27% of cases, a medial approach in 5%, and an inferior approach in 7%. A trocar was used during applicator insertion in 27% of cases. Local anesthetic, sedation, both or neither were administered in 45%, 2%, 41% and 11% of cases, respectively, during applicator placement. The prescription dose was delivered in 42 of 44 treated @entity1 . CONCLUSIONS: Early stage @entity0 can be treated with breast conserving surgery and APBI using electronic brachytherapy. Treatment was well tolerated, and these early outcomes were similar to the early outcomes with @entity3201 -based balloon brachytherapy.
