[Correlations of @entity9597 gene polymorphism and serum XXXX levels with @entity565 predictive index].

@entity1 @entity9597 @entity565 @entity70853 @entity9416
OBJECTIVE: To study the correlations of @entity9597 gene polymorphism and serum @entity9416 levels with @entity565 predictive index (API) in @entity1 . METHODS: One hundred and sixty-seven @entity1 with positive API, 187 @entity1 with negative API and 203 healthy @entity1 (control group) were enrolled. PCR and DNA sequencing were used to identify genotypes of the @entity70853 locus in @entity9597 gene. Serum @entity9416 levels were measured using ELISA. RESULTS: There was no significant difference in the genotype frequencies of the @entity70853 locus in @entity9597 gene among the positive API, negative API and control groups. Serum @entity9416 levels in the positive API group were significantly higher than in the negative API and control groups (P<0.01). In the positive API group, the @entity1 aged less than 2 years had significantly lower serum @entity9416 levels than those aged over 2 years (P<0.01). CONCLUSIONS: There is no correlation between the @entity70853 polymorphism in @entity9597 gene and API results. API positivity is correlated with elevated serum @entity9416 levels. An older age (>2 years) may be a risk factor for increased serum @entity9416 levels in @entity1 with positive API.
