The effects of corneal parameters on the assessment of XXXX in the elderly eye.

@entity1 @entity267 @entity231 @entity168 @entity1358
BACKGROUND: The possible impact of corneal thickness, curvature, and size on the measurement of @entity1358 ( @entity1358 ) has largely been ignored in the normal eye. The aim of this study was to investigate the possible impact of the main corneal parameters on the analysis of @entity1358 values at the central, superior, and temporal parts of the corneal surface. METHODS: All 75 @entity1 (52 females, 23 males) were assessed as part of a pre- @entity231 surgery investigation. The mean age was 75.7 ( @entity168 10.9) years. Confocal microscopy was used to measure @entity1358 and the percentage of six sided cells at the central, superior, and temporal parts of the @entity267 . The Orbscan II topography system was used to measure corneal thickness, topography, and horizontal corneal diameter. RESULTS: The mean central @entity1358 measured was 2488 ( @entity168 301) cells/mm(2), compared with 2525 ( @entity168 505) cells/mm(2) in the temporal @entity267 and 2639 ( @entity168 398) cells/mm(2) in the superior @entity267 . The regional differences in @entity1358 were not significant (p>0.14). The central @entity1358 was significantly correlated to the central (mean 0.593 ( @entity168 0.039) mm, p = 0.021) as well as the temporal (0.628 ( @entity168 0.039) mm, p<0.001) and the superior corneal thickness ( @entity168 0.644 ( @entity168 0.048) mm, p = 0.018). The mean corneal curvature at the centre (7.7 ( @entity168 0.34) mm, p = 0.002) as well as 3 and 5 mm from the apex was significantly related to @entity1358 (p = 0.008 and p = 0.009, respectively). CONCLUSIONS: The study suggests that in an older population, lower @entity1358 values would be expected in thinner and/or steeper corneas.
