Serum procalcitonin predicting mortality in exertional XXXX .

@entity1 @entity1904 @entity281 @entity6167 @entity881
BACKGROUND: The aim of this study was to test if @entity1904 PCT value at the time of admission is a predictor of mortality and/or a diagnostic marker of concomitant infection in exertional @entity6167 . METHODS: 68 @entity1 with exertional @entity6167 admitted to the multidisciplinary intensive care unit were studied. Serum PCT was detected by means of a specific and ultrasensitive immunoluminometric assay within 2 h of admission. The Acute Physiology and Chronic Health Evaluation (APACHE) II score was evaluated within 24 h of admission. RESULTS: There was no significant difference in PCT levels between concomitant infection and @entity281 @entity1 (p=0.712). Elevated PCT level in exertional @entity6167 @entity1 was associated with a more critical pathological state. PCT values in @entity1 with @entity881 ( @entity881 ) were significantly higher than those without @entity881 (p=0.007.). PCT values were also positively correlated with APACHE II scores (r=0.588, p=0.016). PCT values in non-survivors were higher than in survivors at univariate regression analysis (p=0.017). After adjusting for confounders, PCT concentration also remained an independent determinant of mortality (OR 2.98; 95% CI 1.02 to 4.41; p=0.039). Receiver operating characteristic curve for PCT concentration was located above the reference line, which shows an association with mortality. The area under the curve for PCT concentration (0.705; 95% CI 0.547 to 0.862) was statistical significantly (p=0.019). As a predictor of mortality, PCT value was inferior to APACHE II score. CONCLUSIONS: PCT value at the time of admission is an independent predictor of mortality, but maybe not a good indicator of concomitant infection in exertional @entity6167 .
