XXXX insertion/deletion gene polymorphism in general population of west Azarbaijan, Iran.

@entity1 @entity1289
INTRODUCTION: @entity1289 ( @entity1289 ) gene polymorphisms have been studied in different ethnic populations. We assessed the @entity1289 gene insertion/deletion alleles frequencies and genotype distributions in a group of individuals from among the general population of west Azarbaijan, Iran, in order to determine the prevalence of deletion/deletion (D/D), deletion/insertion (D/I) and insertion/insertion (I/I) genotypes. MATERIALS AND METHODS: In a cross-sectional study, 167 healthy individuals were enrolled in a randomized fashion. They were selected from the general population of west Azerbaijan, Iran. Polymerase chain reaction was carried out to determine the @entity1289 D/D, D/I and I/I genotypes. RESULTS: The @entity1289 alleles were D and I in 59.7% and 40.3% of the @entity1 , 59.3% and 40.7% of the @entity1 and 59.6% and 40.4% of all of the @entity1 , respectively. The D/D, D/I, and I/I genotypes were observed in 22 (40.7%), 20 (37%), and 12 (22.2%) @entity1 , 41 (36.3%), 53 (46.9%), and 19 (16.8%) @entity1 , and 63 (37.7%), 73 (43.7%), and 31 (18.6%) @entity1 , respectively. Statistical analysis showed that differences in @entity1289 D and I alleles and genotype frequencies were not significant between the @entity1 and the @entity1 . CONCLUSIONS: In this study on the general population of west Azarbaijan, the frequencies of the @entity1289 D and I alleles were 59.6% and 40.4%. The @entity1289 D/D, D/I and I/I genotypes were seen in 37.7%, 43.7%, and 18.6% of the studied population, respectively.
