[Importance of measuring exposure to the principal indoor allergens in XXXX ].

@entity1 @entity32 @entity565 @entity2774 @entity56 @entity209 @entity6587
Domestic allergens, such as mite and cat allergens, are a leading cause of @entity56 . Allergen exposure is a risk factor for sensitization. Allergens also play a major role in the development of @entity32 and non specific @entity6587 as well as in the apparition and modulation of symptomatic @entity565 . The development of new means of detecting allergens (i.e. immunochemical assays including monoclonal antibodies, quantitative and semiquantitative @entity2774 measurements for mite allergens) has made possible to identify allergens sources and reservoirs. The form in which domestic allergens become airborne is important. The group I and II allergens from mites, the major cockroach allergens are carried on large particles (mean size > 10 microns diameter); in contrast, the major cat allergens are airborne on small particles (40% < 5 microns). @entity2774 , a @entity209 , is used as a marker for mite feces and is correlated with the presence of major allergens from mites. A colorimetric method (Acarex-TestR) provides a simple and inexpensive method of assaying indoor mite allergen exposure for both doctor and @entity1 alike. By using Acarex-TestR it is possible to evaluate the mite allergen exposure for a population in a particular country. The detection of allergens sources and reservoirs, the quantification of domestic allergens has enabled the evaluation of the effect of a reduction in allergen exposure to be better assessed. Recognition of the risks, environmental control and reduction in allergen loads, should be among the objectives of @entity565 management.
