Adjuvant radiotherapy in XXXX .

@entity1 @entity5 @entity2675
PURPOSE: To determine retrospectively the outcome of postoperative radiation therapy in @entity2675 . Local/distant control was assessed with attention to age, stage, lymph node involvement, histopathological differentiation and hormone receptor status. MATERIALS AND METHODS: Thirty-one male @entity1 were irradiated postoperatively at the chest wall (mean dose 50 Gy) and 16 @entity1 received radiation to regional lymph nodes. @entity5 distribution by stage was: stage 0 (9.7%), stage I (22.6%), stage II (32.2%) and stage III (35.5%). Nine @entity1 were subjected to additional hormone therapy and three @entity1 to chemotherapy. RESULTS: Local control was achieved in 30/31 (96.8%) @entity1 . Kaplan-Meier estimates of overall survival (OS), disease specific (DSS) and disease free survival (DFS) at 5 years were 77% (95% confidence interval (CI), 0.61-0.93), 84% (CI, 0.69-0.98) and 73% (CI, 0.57-0.91), respectively. Five-year DFS for stage 0 + I, II and III was 100, 56.3 and 67.3%, respectively. Favourable results were observed in @entity1 with negative axillary nodes with 5-year OS/DFS of 90.9% (CI, 0.74-1.0). For lymph node positive @entity1 DFS was 71% (CI, 0.4-1.0). @entity1 who presented lymph node metastases with extracapsular extension the 5-year OS was 80% (CI, 0.45-1.00), but the DFS was 0%. Stage of disease, lymph node involvement and histological differentiation were found to have statistically significant influence on DFS, but not on OS. CONCLUSION: Application of postoperative radiotherapy approved in females resulted in one local relapse in our study population. Other treatment modalities (hormone therapy/chemotherapy) should continue to be considered a necessary treatment option for appropriately selected @entity1 .
