Radiofrequency ablation of invasive XXXX followed by delayed surgical excision.

@entity1 @entity0 @entity41 @entity39 @entity5 @entity10585 @entity189
BACKGROUND: Radiofrequency ablation (RFA) is gaining acceptance as a treatment modality for several @entity5 types. However, its use in @entity1 with @entity0 remains investigational. The current study was undertaken to determine the feasibility of treating small @entity0 with RFA and to evaluate the postablation magnetic resonance imaging scans (MRI) and histologic findings. METHODS: @entity1 with core-needle biopsy-proven @entity189 (< 2 cm in greatest dimension) underwent ultrasound-guided RFA under local anesthesia. Surgical excision was undertaken 1-3 weeks later. All @entity1 had breast MRI scans performed before ablation and repeated within 24 hours of surgery. RESULTS: Ten @entity1 completed the treatment and experienced minimal or no discomfort. The mean @entity5 size was 1.2 cm (range, 0.8-1.6 cm). The mean time required for ablation was 13.8 minutes (range, 7-21 minutes). There were no treatment-related complications other than minimal breast ecchymosis. A pre-RFA MRI scan showed enhancing @entity5 in 9 of 10 (90%) @entity1 . A post-RFA MRI scan revealed no residual lesion enhancement in 8 of these 9 @entity1 (89%), and the zone of ablation was demonstrated in all @entity1 . One @entity1 had residual enhancement anteriorly consistent with @entity41 , which was confirmed histologically. Evaluation of the remaining ablated lesions revealed a spectrum of changes ranging from no @entity41 to @entity39 with recognizable malignant cells. Immunostains for @entity10585 /18 were negative in these recognizable malignant cells. CONCLUSIONS: RFA of small @entity0 can be performed under local anesthesia in an office-based setting. A postablation MRI scan appears to predict histologic findings, although @entity5 viability needs to be assessed in a long-term study.
