Contrast-enhanced ultrasonographic findings of different histopathologic types of XXXX .

@entity1137 @entity8 @entity1377 @entity0 @entity5 @entity189 @entity513
BACKGROUND: The new application of @entity8 ( @entity8 ) in the diagnosis of breast masses has evolved quickly only in recent years. Nevertheless, mixed results owing to the overlap in characteristics of benign and malignant lesions are simultaneously discovered by most studies, partially attributed to different histopathologic characteristics of @entity0 . PURPOSE: To explore the characteristics of different histopathologic types of @entity0 at real-time gray-scale @entity8 and evaluate its diagnostic value. MATERIAL AND METHODS: One hundred and one histopathologically confirmed malignant lesions were included. We retrospectively reviewed the contrast-enhanced ultrasonographic findings including morphologic features, quantitative parameters, and correlated them with histopathology. True-positive rate was calculated to assess the diagnostic performance of @entity8 . RESULTS: The 101 @entity5 displayed irregular shape (72 [71%]), poorly-defined margin (73 [72%]), penetrating or tortuous surrounding vessels (79 [78%]), heterogeneous enhancement (84 [83%]), including focal perfusion defects (24 [24%]). For each histopathologic type, 87% (58/67) of @entity513 ( @entity513 ) showed heterogeneous enhancement. Of all the 24 perfusion defects, @entity513 account for 88% (21/24). Low average peak intensity (PI) of 4.9 was detected in this type. @entity513 in situ (DCIS) excellently showed the features of irregular shape (82% [14/17]), poorly-defined margin (82% [14/17]), heterogeneous enhancement (94% [16/17]). While 83% (5/6) of @entity189 exhibited regular shape, well-defined margin, homogenous enhancement, and high average PI value of 9.6. @entity1137 showed similar enhancement pattern to that of @entity513 . Intraductal @entity1377 displayed high average PI value of 8.1. The overall true-positive rate for conventional US and @entity8 was 88%, 86%, respectively. DCIS, @entity189 , and @entity1377 achieved an improved true-positive rate (94%, 100% and 100%, respectively). CONCLUSION: The imaging characteristics of @entity8 are variable in different histopathologic types of @entity0 . @entity8 does not appear to be superior to conventional ultrasound as a diagnostic tool overall, however, it is a useful adjunct to conventional ultrasound in diagnosing some special types of @entity0 .
