Infraslow EEG changes in infantile XXXX .

@entity1 @entity410 @entity739 @entity2473 @entity302 @entity6191
PURPOSE: @entity739 ( @entity739 ) are a devastating @entity302 of infancy. Analysis of infraslow EEG activity (ISA) has shown potential in the presurgical evaluation of @entity1 with @entity302 and in differentiating between focal and @entity6191 . Infraslow EEG activity analysis may provide insights into the pathophysiology of some @entity302 , such as @entity739 . To our knowledge, there are no published reports describing ISA in @entity1 with @entity739 . The purpose of this study was to describe ictal patterns of ISA in @entity1 with @entity739 and to correlate with clinical data. METHODS: EEG recordings of all cases of @entity739 in the past 10 years at the Alberta @entity1 's Hospital were reviewed. Inclusion criteria were a technically adequate video EEG recording that captured at least one @entity2473 . For each @entity1 , the first 10 confirmed @entity2473 were examined. Spasms were evaluated for changes in ISA, which were either generalized, lateralized, or absent ISA (g-ISA, l-ISA, or n-ISA, respectively). Results were correlated with treatments, clinical course, and information pertinent to likely etiology of the @entity739 . RESULTS: A total of 77% of @entity2473 were associated with ISA; 57% with g-ISA, 20% l-ISA, and 21% n-ISA. All @entity1 with exclusively g-ISA showed at least a partial response to initial therapy, while this was the case in 66.7% of those with at least some l-ISA and 50% of those with exclusively n-ISA. Other @entity410 types occurred in 60% of @entity1 with exclusively g-ISA versus 83% with some l-ISA and all @entity1 with exclusively n-ISA. CONCLUSIONS: Ictal ISA was observed in the majority of @entity739 . Trends were observed suggesting that the presence of exclusive g-ISA changes may be a positive prognostic factor in @entity739 .
