Positive predictive value of International Classification of Diseases, 10th revision, diagnosis codes for cardiogenic, @entity3485 , and @entity326 in the Danish National XXXX Registry.

@entity1 @entity326 @entity1457 @entity2286 @entity3485 @entity1455
BACKGROUND: Large registries are important data sources in epidemiological studies of @entity1457 , if these registries are valid. Therefore, we examined the positive predictive value ( @entity2286 ) of diagnosis codes for @entity1457 , the procedure codes for inotropic/vasopressor therapy among @entity1 with a diagnosis of @entity1457 , and the combination of a @entity1457 diagnosis and a code for inotropic/vasopressor therapy in the Danish National @entity1 Registry (DNPR). METHODS: We randomly selected 190 inpatients with an International Classification of Diseases, 10th revision (ICD-10) diagnosis of @entity1457 at Aarhus University Hospital from 2005-2012 using the DNPR; 50 @entity1 were diagnosed with @entity1455 , 40 @entity1 with @entity1457 , and 100 @entity1 with @entity326 . We used medical charts as the reference standard and calculated the @entity2286 with 95% confidence intervals (CI) for overall @entity1457 and for each type of @entity1457 separately. We also examined the @entity2286 for inotropic/vasopressor therapy and the @entity2286 for @entity1457 when a concurrent code for inotropic/vasopressor therapy was also registered. RESULTS: The @entity2286 was 86.1% (95% CI: 79.7-91.1) for @entity1457 overall, 93.5% (95% CI: 82.1-98.6) for @entity1455 , 70.6% (95% CI: 52.5-84.9) for @entity1457 , and 69.2% (95% CI: 57.7-79.2) for @entity326 . The @entity2286 of use of inotropes/vasopressors among @entity1457 @entity1 was 88.9% (95% CI: 79.3-95.1). When both a @entity1457 code and a procedure code for inotropic/vasopressor therapy were used, the @entity2286 for @entity1457 overall was 93.1% (95% CI: 84.5-97.7). ICD-10 codes for subtypes of @entity1457 and simultaneously registered use of inotropes/vasopressors provided PPVs of 96.0% (95% CI: 79.6-99.9) for @entity1455 , 69.2% (95% CI: 38.6-90.9) for @entity1457 , and 82.4% (95% CI: 65.5-93.2) for @entity326 . CONCLUSIONS: Overall, we found a moderately high @entity2286 for @entity1457 in the DNPR. The @entity2286 was highest for @entity1455 but lower for @entity3485 and @entity326 . Combination diagnoses of @entity1457 with codes for inotropic/vasopressor therapy further increased the @entity2286 of @entity1457 overall, and for cardiogenic and @entity326 diagnoses.
