Mortality among XXXX herbicide manufacturing workers.

@entity1 @entity21750 @entity1893 @entity5 @entity2 @entity12472 @entity35
@entity12472 produces mammary gland @entity5 in one strain of @entity35 and has been classified as an endocrine modulator. Epidemiologic studies have reported associations between agricultural use of @entity12472 and several forms of @entity5 . This study evaluated mortality patterns among workers at a plant that made @entity12472 and other @entity21750 herbicides. The study covered the time period 1970-1997 and included 2213 @entity1 employed for at least 6 mo in operations related to the manufacture or formulation of @entity12472 and other @entity21750 herbicides at a plant in Louisiana (LA). Vital status was determined for all but six subjects. Standardized mortality ratios (SMRs) with 95% confidence intervals (CIs) compared employees' mortality rates with those of the LA industrial corridor general population. Subjects had a total of 32,473 @entity1 -years of observation and a median of 15.8 yr since hire. There were 84 observed/118 expected deaths from all causes combined (SMR = 72, CI = 57-89) and 22/21 total @entity5 deaths (SMR = 106, CI = 66-160). Subjects had 4/1.1 deaths from @entity1893 (SMR = 372, CI = 101-952); this increase was not concentrated in the subgroup with long duration of employment and many years since hire. There were 6/4.8 (SMR = 124, CI = 46-271) digestive @entity5 and 7/6.3 (SMR = 112, CI = 45-230) @entity2 deaths. Data on other forms of @entity5 were sparse. This study was limited by its small size, by the relatively young age and short follow-up of its subjects, and by the lack of exposure data. It did not provide evidence that employment in @entity21750 herbicide manufacturing and formulating operations was associated causally with overall or cause-specific mortality.
