Autonomic response to periodic leg movements during sleep in XXXX .

@entity1 @entity10522 @entity16 @entity2724 @entity591 @entity18206 @entity65 @entity1168 @entity25
STUDY OBJECTIVES: To test the hypothesis of @entity16 in @entity1 with @entity2724 ( @entity2724 ) by assessing the physiologic activations associated with @entity10522 ( @entity10522 ). DESIGN: Sleep and heart rate (HR) were recorded during 1 night of polysomnography. SETTING: Data were collected at the @entity25 Center, Sacre-Coeur Hospital, Montreal, Canada. @entity1 : Data from 14 @entity1 with @entity2724 (6 @entity1 , 8 @entity1 , mean age: 52.5    11.9 years) were compared with data from 14 healthy control subjects matched for age and sex. INTERVENTIONS: NA. MEASUREMENTS AND RESULTS: Analyses included sleep stages, @entity10522 , microarousals, RR intervals converted into beats per minute on segments lasting 25 heartbeats (10 RR intervals before @entity10522 and 15 after), and cardiac-activation amplitudes. A Group-by-Heartbeat interaction was noted for @entity10522 without microarousals; the @entity1 had a @entity591 of lower amplitude and a delayed and lower-amplitude @entity1168 , compared with normal control subjects. Similar significant HR modifications were observed for @entity10522 with microarousals between @entity1 with @entity2724 and control subjects. @entity1 with @entity2724 had a reduced magnitude of cardiac activation associated with @entity10522 with and without microarousals, as compared with control subjects. A negative correlation was noted between cardiac-activation amplitude and age in @entity1 with @entity2724 , but no correlation with @entity10522 index was found in either @entity1 with @entity2724 or control subjects. CONCLUSION: A significant reduction in the amplitude of @entity10522 -related HR responses in both @entity591 and @entity1168 was found in @entity1 with @entity2724 . These findings favor the physiologic relevance of the action of @entity18206 on autonomic function that may be of clinical significance, i.e., increasing the risk of @entity65 .
