Pathogenesis of @entity1902 caused by XXXX in cultured marine fish.

@entity11784 @entity25594 @entity6941 @entity39 @entity37765 @entity1902 @entity563 @entity6953
Serious mortality among the cultured grouper @entity6941 , characterized by a swollen intestine containing yellow fluid ( @entity1902 ), occurred in 1993 in Taiwan. A bacterium isolated from the intestinal fluid and head kidney of moribund groupers was identified as @entity11784 . Since then, the same Vibrio species has also been isolated from moribund black sea bream Acanthopagrus schlegeli, @entity37765 sea bream A. latus, Japanese sea bass @entity6953 , and @entity25594 @entity25594 suffering from the same syndrome. Each isolate was virulent to the respective fish. Recently, a similar syndrome, flounder @entity39 , also caused by @entity11784 in summer flounder Paralichthys dentatus, was reported in Rhode Island. The extracellular products (ECPs) of @entity11784 strains EmI82KL (from grouper), Rd (from @entity25594 ), and SfUSA (from summer flounder, U.S.A.) were virulent to the grouper or @entity25594 . A 33-kDa @entity563 protease partially purified from the ECP of strain EmI82KL was lethal to the fish. All the moribund or killed fish exhibited @entity1902 except those killed within 12 hours. This report is the first to show that intraperitoneal injection of the ECP or protease in the fish is virulent and can reproduce @entity1902 . The @entity563 protease was suggested as a major toxin in the grouper or @entity25594 secreted by @entity11784 .
