[Early and postponed percutaneous coronary interventions in acute period of XXXX ].

@entity1 @entity3224 @entity1188 @entity583 @entity204
Aim of the study was elaboration of indications to the application of postponed percutaneous coronary interventions (PCI) in acute period of @entity583 ( @entity583 ) in @entity1 without prior thrombolytic therapy. We fulfilled comparative assessment of efficacy of 3 strategies of treatment of 810 @entity1 admitted to the N.V. Sklifosovsky Institute of Urgent @entity3224 from 2003 to 2007: primary PCI carried out within first 12 hours (n=32), postponed PCI in acute period because of initially elevated risk (n=90), conservative treatment without reperfusion therapy (n=688). Elevated risk of @entity204 according to TIMI score was used as the basis for establishment of indications for postponed interventions. Right ventricular involvement and repeat MI were considered as additional predictors. The data obtained indicate that elevated risk of @entity204 allows to detect @entity1 with high rate of persisting occlusions and subtotal stenoses in @entity1188 related artery. Reperfusion therapy appears to be the main component of treatment of such @entity1 . Necessity to perform primary PCI within first 12 hours does not exclude possibility of its later use in acute period of MI. Both strategies allow to substantially lower rates of complications and lethal outcomes. Shortening of terms of application of reperfusion therapy gives an opportunity to prevent most of unfavorable outcomes. Success of postponed interventions in acute period of MI opens opportunities of their active use in @entity1 from other hospitals.
