Ploidy assessment of benign and malignant XXXX by flow cytometry. A clinicopathologic study.

@entity43 @entity1 @entity2007 @entity146 @entity5
In a prospective study, 112 fresh @entity43 samples were collected from 83 consecutive @entity1 . Cellular DNA content was measured by flow cytometry. All the benign (n = 24) and semimalignant (n = 6) @entity5 were diploid. Of 50 @entity5 , 24 (48%) were diploid and 26 (52%) were @entity2007 . Aneuploidy was more frequent in the advanced stages of the disease, in @entity5 of low degree of differentiation, and in older @entity1 . The @entity1 with @entity5 had smaller @entity5 and more often ascites. The fraction of cells with S-phase DNA content was higher in the @entity5 . No association was seen to the @entity5 type. Ploidy determination is objective and reproducible. Aneuploidy associates to most negative prognostic factors in @entity43 and may reflect the @entity146 . The ploidy status may be taken into consideration in the stratification of @entity1 of comparable risk for treatment studies.
