Impaired postoperative outcome in chronic @entity167 abusers after curative resection for XXXX .

@entity1 @entity295 @entity167 @entity1887 @entity2 @entity1068
OBJECTIVE: It has been demonstrated that chronic @entity167 misusers, who drink at least 60 g of @entity1068 per day, are suffering increased postoperative morbidity after various non-pulmonary surgical procedures. The aim of this study was to evaluate the association between @entity167 consumption and postoperative morbidity and mortality after potential curative resection for @entity2 . METHODS: The records of all @entity1 who underwent curative resection for @entity2 in a single University Centre in Cardiothoracic surgery during 1997 and 1998 were retrospectively reviewed. One hundred and seven @entity1 , 42 @entity1 and 65 @entity1 , median age of 64 (33-79) years, were included and subdivided with regard to @entity167 consumption. There were 26 pneumonectomies, 68 lobectomies and 13 lesser resections. Clinical complications occurring within 30 days after surgery and requiring therapy, were registered and subdivided into major, potentially lethal complications, and minor complications. Mortality within 30 days after surgery was also registered. RESULTS: @entity1 drinking at least 5 drinks per day had increased postoperative mortality, 3/13 versus 2/94 (odds ratio (95% confidence limits): 13.80 (2.06-92.68); P=0.007). The rate of major, live threatening complications including @entity295 and @entity1887 was significantly increased among @entity1 drinking at least 5 drinks per day 6/13 versus 19/94 (odds ratio (95% confidence limits): 3.38 (1.02-11.25); P=0.047) in univariate analysis. However, in multivariate analysis this association was not significant. CONCLUSION: Postoperative mortality after curative resection for @entity2 was significantly increased among @entity1 drinking at least 5 drinks of @entity167 per day.
