Nodal marginal zone XXXX resembling @entity6872 arising from a plasma cell variant of localized @entity12692 : a case report.

@entity1 @entity6872 @entity5 @entity12692 @entity3202 @entity1892 @entity1073
Nodal marginal zone @entity1892 (NMZBL) occasionally represents prominent plasma cell differentiation. Recently, primary lymph node @entity6872 has been suggested to represent an extremely plasmacytic differentiation of NMZBL. We here report a case of NMZBL showing histological features resembling @entity6872 arising from a plasma cell variant of localized @entity12692 (PCLCD). The @entity1 was a 69-year-old Japanese female with a 20-year history of a right inguinal mass. Histologically, a prominent proliferation of plasma cells occupied the interfollicular area of the central portion of the lymph node, whereas @entity1073 ( @entity1073 ) cells were the main cellular component in the peripheral portion of the lymph node. Although most of the plasma cells were mature 'Marshalko-type', occasional atypical forms with enlarged nuclei were also present. The majority of the lymphoid follicles had @entity3202 or regressive germinal centers. A few lymphoid follicles were colonized by @entity1073 cells. Immunohistochemistry study revealed that both plasma cells and some @entity1073 cells had a monotypic intracytoplasmic lambda light chain. When monoclonal plasma cell infiltration is observed in PCLCD, the light chains are mostly restricted to the lambda chain. This case suggests that some plasma cell-containing @entity5 arising from PCLCD may represent a variant of NMZBL.
