A Graded Evaluation of Outcomes Following Pancreaticoduodenectomy with Major Vascular Resection in XXXX .

@entity1 @entity788 @entity4988 @entity5 @entity797
UNASSIGNED: Previous studies examining short- and long-term outcomes of pancreaticoduodenectomy with vascular resection for @entity788 have not graded perioperative complication severity. These studies may provide incomplete assessments of the efficacy of vascular resection. In the current study, we evaluated 36 @entity1 who had pancreaticoduodenectomy with major vascular resection. These were matched 1:3 by @entity5 stage and age to @entity1 who had pancreaticoduodenectomy without vascular resection. Charts were reviewed to identify all complications and 90-day readmissions. Complications were graded as either severe or minor adverse postoperative outcomes, taking into account the total length of stay. There were no statistical differences in @entity1 demographics, comorbidities, or symptoms between the groups. @entity1 who had vascular resection had significantly increased rates of severe adverse postoperative outcomes, readmissions, lengths of hospital stay, as well as higher hospital costs. @entity4988 and major vascular resection were independent predictors of severe adverse postoperative outcomes. On multivariate @entity797 -regression survival analysis, @entity1 who had vascular resection had decreased recurrence-free (12 vs. 17  months) and overall (17 vs. 29  months) survival. Major vascular resection was a predictor of mortality, may be an independent prognostic factor for survival, and may warrant incorporation into future staging systems.
