Differences in glomerular leukocyte infiltration between @entity8 and XXXX .

@entity1 @entity8 @entity469 @entity5824 @entity3630 @entity1453 @entity1454 @entity9536 @entity2071 @entity631
BACKGROUND: An important aspect in glomerular nephritic processes is the enhanced influx of leukocytes into the glomerulus. METHODS: To investigate the mechanisms of intraglomerular leukocyte infiltration in @entity8 ( @entity8 ) and @entity3630 ( @entity3630 ), we immunohistochemically examined the intraglomerular expression of @entity1453 ( @entity1453 , @entity1453 / @entity1454 ), @entity9536 , @entity9536 / @entity1454 ) and @entity2071 ( @entity2071 , @entity2071 ) together with glomerular deposition of C3c and fibrinogen. RESULTS: In @entity8 (n=42), @entity1453 + cells were distributed mainly in glomeruli with intense expression of @entity2071 , and there was a positive correlation (P<0.001) between the number of @entity1453 + cells and the degree of @entity2071 expression. @entity9536 + cells had no correlation with glomerular C3c deposition, but had a significant correlation with fibrinogen deposition (P<0.05). The number of @entity1453 + cells was significantly greater than of @entity9536 + cells (P<0.05). The number of @entity1453 + cells was strongly correlated with that of @entity469 + cells (P<0.00001). In @entity3630 (n= 43), on the contrary, @entity9536 + cells correlated only with C3c deposition (P<0.001), and they were observed mainly in peripheral loops of glomerular capillaries where C3c was deposited with a similar distribution. However, there was no relationship between @entity1453 + cells and @entity2071 expression. The number of @entity9536 + cells was greater than that of @entity1453 + cells (P<0.0001), and most @entity9536 + cells were identical to @entity5824 + cells. CONCLUSION: These results indicate the possibility that different mechanisms may cause glomerular leukocyte infiltration in various forms of @entity1 @entity631 . The @entity1453 / @entity2071 pathway may play an important role in glomerular leukocyte infiltration in @entity8 , while the @entity9536 /complement pathway may be important in @entity3630 . The former may promote mainly the infiltration of @entity469 + cells, and the latter may promote that of @entity5824 + cells. In addition, @entity9536 + cells may act as fibrinogen and complement receptors in @entity8 and @entity3630 , respectively.
