Lymphatic spread of mesenchymal @entity703 to metastatic parathymic lymph nodes in XXXX .

@entity5 @entity16 @entity982 @entity3 @entity35 @entity703
@entity35 mesenchymal @entity703 cells (NeDe) transplanted under the kidney capsule of F344 @entity35 resulted in @entity3 in the parathymic lymph nodes. @entity5 cells were isolated from these @entity5 -bearing lymph nodes and 106 cells were implanted under the kidney capsule. @entity5 growth after this implantation could be traced within six days. India ink was implanted to prove that there is a connection between the lymphatic vessels of the kidney capsule and the parathymic lymph nodes. The distribution of the radioligand 18FDG in different organs also provided evidence that the parathymic lymph nodes are the primary sites of metastatic @entity5 growth. @entity5 growth was followed after staining sections of biopsies of normal, @entity5 kidneys and parathymic lymph nodes embedded in @entity982 . The progression of @entity5 formation was seen as a frontline between the healthy and @entity5 bearing tissue. This demarcation line was sharp at the beginning of the invasion and at the peripheral regions of the @entity5 , while the central region infiltrated into the healthy kidney tissue. The initial invasion gradually turned to an infiltration resulting in the disruption of the renal tissue, especially at the periphery. Accumulation of lipids and flow of blood to the lymphatic vessels was due to the lack of angiogenesis, leading to an increased pressure of the interstitial fluid. @entity16 ultimately led to the appearance of blood and the growth of @entity5 cells in parathymic lymph nodes. The kidney capsule-parathymic lymph node complex is proposed as a suitable metastatic model for the isolated in vivo examination of @entity5 development and for the analysis of secondary @entity5 .
