Ultraviolet radiation-induced XXXX : age and maximum acceptable dose.

@entity35 @entity5999 @entity231
PURPOSE: To investigate the effect of age on ultraviolet radiation-B (UVR-B)-induced @entity231 and to detect the maximum acceptable dose in @entity35 of different age groups. METHODS: Four age groups of 20 @entity35 each, aged 3, 6, 10, and 18 weeks, were included. Each age group was divided into five UVR-B dose subgroups. The @entity35 were unilaterally exposed to UVR- @entity5999 (max) = 302.6 nm, lambda(0.5) = 4.5 nm). The incident dose on the cornea varied between 0 and 8 kJ/m(2). One week after exposure, the @entity35 were killed, both lenses were extracted, the intensity of forward light-scattering was measured, and photographs were taken. The sensitivity of the lens to UVR-B was estimated as the maximum acceptable dose. RESULTS: The maximum acceptable dose for 3-, 6-, 10-, and 18-week-old @entity35 was estimated to be 1.4, 2.7, 4.3 and 5.2 kJ/m(2), respectively. CONCLUSIONS: Young @entity35 were more sensitive to UVR-B than old ones. Age should be considered when estimating the risk for UVR-B-induced @entity231 .
