Occurrence of bacteremia during and after XXXX .

@entity1 @entity295 @entity548 @entity326 @entity177 @entity1200 @entity35 @entity413
In recent research, @entity548 and @entity326 have been studied as two separate entities. We have developed a treated model of @entity548 in which unrestrained and unanesthetized @entity35 are bled to a mean arterial pressure of 30 torr until 80% of the maximum shed volume must be returned. @entity35 are maintained preshock and treated post shock with a 20% @entity413 -electrolyte solution. Survival of these animals is 62% at 24 hours post shock and all animals are dead at 72 hours post shock. Blood cultures obtained during shock become positive at 2 hours into the shock period and are significant compared to controls at 3 to 5 hours of shock (p less than 0.0001). Blood cultures obtained after the period of shock are significantly positive at 24 and 48 hours post shock (p less than 0.05) compared to controls. Intrashock cultures are monomicrobial; the majority of post-shock cultures are polymicrobial. All cultured organisms are normal @entity35 enteric flora. Histologic changes of @entity177 are also demonstrated post shock. We suggest that bacterial invasion, possibly from the gut, plays a role in the @entity295 seen in @entity1 following severe @entity548 . @entity295 may precede rather than follow the @entity1200 which accompanies shock.
