Influence of moderate drinking on XXXX and @entity1735 metabolism.

@entity1 @entity2642 @entity2353 @entity10043 @entity1735 @entity375 @entity1068 @entity413 @entity414
BACKGROUND: We examined the influences of a moderate intake level of three types of alcoholic beverages--beer, whisky, and Shochu (Japanese distilled liquor)--on @entity10043 and @entity1735 metabolism and excretion in healthy male volunteers, concerning (1) the extent of contribution of @entity10043 bodies contained in beer to @entity414 metabolism and (2) a comparison between two types of distilled spirits with (whisky) and without (Shochu) aging in oak wood barrel storage. METHODS: Three sets of studies were conducted in which 10 to 13 healthy adult @entity1 were instructed to drink three types of alcoholic beverages at a slightly higher level (0.8 ml of @entity1068 equivalent/kg body weight) than moderate drinking (approximately 30.4 ml or less for @entity1 ). A low @entity10043 beer was test-manufactured by treating nucleosides that were contained in wort and remained in beer with @entity10043 @entity2353 phosphorylase derived from Ochrobacterium anthropi, thereby converting them into corresponding @entity10043 bases that were easily assimilated by beer @entity375 . RESULTS: Although beer intake enhanced the level of serum @entity414 by 13.6%, blood @entity413 by 26.7%, and insulin level by 5.1-fold, drinking a moderate level of distilled liquor (whisky, Shochu) did not increase the serum @entity414 level or the other two parameters. The serum @entity414 level observed after drinking beer with a @entity10043 body concentration reduced by 28% (68% in @entity2642 and @entity10043 bases) was almost identical to the level observed after drinking regular beer. Whisky has been found to have a property that decreases the serum @entity414 level. Excretion of @entity414 from blood is increased by 27% after drinking whisky. CONCLUSIONS: Moderate drinking of distilled liquors did not enhance serum @entity414 level, blood @entity413 , or insulin level in healthy male subjects. Increased serum @entity414 after beer intake could not be explained mostly with their @entity10043 body congeners. Whisky showed the eliminative property in serum @entity414 through excretion of it from blood to urine. At a moderate drinking level, beer and whisky have different effects on @entity10043 metabolism or excretion.
