[A case of XXXX with umbilical metastasis that responded to TS-1 with low-dose @entity900 ].

@entity1 @entity1819 @entity900 @entity420 @entity356
An umbilical metastasis of @entity356 is known as Sister Mary Joseph's nodule. It ordinarily indicates a poor prognosis because umbilical metastasis often develops with peritoneal dissemination. Herein, we report a case of umbilical metastasis of @entity356 that showed good response to chemotherapy, including the oral anticancer agent TS-1. The @entity1 was a 55-year-old @entity1 in which @entity356 was found by upper gastrointestinal series. Physical examination revealed an umbilical nodule that had an irregular surface and a hard consistency. Ultrasonography showed a 15 x 10 mm hypoechoic mass under the umbilicus. Core needle biopsy of the umbilical mass revealed @entity420 . Peritoneal dissemination was proved by diagnostic laparoscopy. Oral anticancer agent TS-1 was administered with low-dose @entity900 . The @entity1819 and umbilical nodule showed marked response to the chemotherapy and the response continued for 20 months. The @entity1 died of disease progression 31 months after the initiation of the treatment.
