Pulmonary vascular responsiveness in cold-exposed XXXX .

@entity519 @entity358 @entity750 @entity112 @entity551 @entity291
The pulmonary vascular responses to acute @entity519 and to infusions of @entity112 and @entity750 ( @entity750 ) were recorded in unanesthetized standing bull @entity291 under neutral (16-18 degrees C) and cold (3-5 degrees C) temperature conditions. Cold exposure alone resulted in a significant increase in pulmonary arterial wedge pressure from 10.2 +/- 3.5 to 15.9 +/- 4.9 Torr (1 Torr = 133.322 Pa). Resistance to blood flow between the pulmonary wedge and the left atrium significantly increased from 0.50 +/- 0.51 to 1.21 +/- 0.78 mmHg . L-1 . min-1 (1 mmHg = 133.322 Pa) with cold exposure. This apparent pulmonary venoconstrictor response to cold exposure was further evaluated to determine if @entity519 , @entity112 , or @entity750 responsiveness was altered by cold exposure. Twelve minutes of @entity519 @entity551 , heart rate, and respiratory rate similarly in cold and neutral temperatures. Cold exposure did not alter the dose-related @entity551 in response to @entity112 . Similarly, the decreases in systemic arterial pressure and heart rate and @entity551 in response to @entity750 were not significantly different in cold and neutral conditions. It was concluded that acute, mild cold exposure results in an increase in resistance to blood flow in the @entity358 without a general increase in pulmonary vascular reactivity, as measured by responses to @entity519 , @entity112 , and @entity750 .
