[Prevention and therapy of delirium XXXX with @entity38857 ].

@entity1 @entity38857 @entity6767 @entity167 @entity16 @entity14935 @entity1245 @entity21
One hundred chronic alcoholics, who were hospitalized in our ward for @entity16 directly or indirectly due to a prolonged and continual consumption of @entity167 , have been treated with @entity38857 in doses varying from 600 up to 1200 mg/die. The drug was administered either per os or by injection. 50 of these @entity1 were given, at the same time, graded doses of @entity167 per os. The purpose of this study was to analyse the preventive and therapeutical effects of the drug both on ten "target symptoms" examined separately, and on the onset and duration of the @entity167 @entity6767 . We have noticed that decreasing doses of @entity167 , in the first days of hospitalization, were unable to reduce significantly the onset of fits of delirium @entity14935 . @entity38857 showed a reasonably good therapeutical activity on some features of the "target symptoms": it shortened the average duration of the symptoms, while it did not prove better than @entity1245 in inhibiting the onset of the same. The drug was unable to prevent the onset of the @entity6767 , and, even if it had a favourable control over the symptoms, it was unable to shorten their duration. The mortality rate was similar to that of other reviews where @entity1245 , or major drugs acting on the nervous system, were employed. The sedative action of @entity38857 , even at higher doses, was insignificant, and its hypnotic effect almost absent. No @entity21 have been observed, at least up to 1000 mg/die.
