Hyperbilirubinaemia: its utility in non-perforated XXXX .

@entity1 @entity697 @entity698 @entity648 @entity2286 @entity532 @entity1851
BACKGROUND: The diagnosis of @entity697 is made using clinical findings and investigations. Recent studies have suggested that serum @entity648 , a cheap and simple biochemical test, is a positive predictor in the diagnosis of appendiceal perforation and may be more specific than @entity1851 ( @entity1851 ) and white cell count (WCC). The aim of this study was to investigate the utility of the serum @entity648 level in @entity1 with suspected acute but non-perforative @entity698 . METHODS: A retrospective chart review of 213 @entity1 who presented with suspected @entity698 in a 6-month period to Nambour General Hospital was performed. Serum @entity648 , WCC and @entity1851 were recorded and analysed as to their utility in relation to the final diagnosis. RESULTS: A total of 196 @entity1 underwent an appendicectomy and 41 of these were negative. The specificity of hyperbilirubinaemia for @entity698 overall was 0.83 with a positive predictive value ( @entity2286 ) of 0.86, compared with @entity1851 (specificity 0.40, @entity2286 0.75) and WCC (specificity 0.67, @entity2286 0.85). The area under the receiver operating characteristic curve for @entity648 was 0.6289 compared to 0.6171 for @entity1851 and 0.7219 for WCC. A subgroup analysis of those with @entity532 demonstrated a @entity2286 for @entity648 of 0.66 compared to 0.58 for WCC and 0.34 for @entity1851 in agreement with the literature. Subgroup analysis of hyperbilirubinaemia in @entity698 demonstrated a @entity2286 of 0.81 compared to @entity1851 (0.71) and WCC (0.82). CONCLUSION: @entity648 had a higher specificity than @entity1851 and WCC overall in @entity1 with @entity698 . Hyperbilirubinaemia had a high @entity2286 in @entity1 with @entity698 .
