XXXX : a clinicopathological experience.

@entity1 @entity135 @entity459 @entity6685 @entity1373 @entity189 @entity8611 @entity3243 @entity652
BACKGROUND: @entity3243 form a small percentage of @entity135 . @entity459 is caused by @entity3243 , @entity1373 or, rarely, a @entity189 . MATERIALS AND METHODS: This is a retrospective study of 48 parathyroidectomies received in the Department of Pathology of a major teaching hospital over a period of 10 years. Clinical, biochemical and radiological details were retrieved from medical records. Information regarding routine gross and microscopic examination findings (including frozen section and paraffin sections) was retrieved from departmental records. RESULTS: We had 43 @entity652 , three @entity1373 and two @entity189 . The most common age group was 21-30 years. The female:male ratio was 2.5:1. Most @entity1 presented with skeletal manifestations. The pre-operative diagnosis was assisted by ultrasonography in 11 cases, computerized tomography of the neck in 10 cases and sestamibi scans in three cases. Intra-operative @entity6685 monitoring was performed in one case of @entity652 . Frozen section was requested in 28 of 48 cases. There was a discrepancy between frozen section diagnosis and paraffin section diagnosis in two cases. CONCLUSION: Histopathologic diagnosis is an important guide to decide the type of surgical management. Although pathologic features of @entity3243 are diagnostically reliable, those of the more commonly encountered lesions of @entity652 and @entity1373 may be overlapping and, therefore, indistinctive, more so if only a single gland is available for examination. Because @entity8611 are only occasionally encountered by the surgical pathologist, awareness of the spectrum of histologic features along with knowledge of recent trends in diagnosis and surgical management are important.
