Differential effects of n-3 fatty acids on the regression of @entity731 in coronary arteries and the aorta of the XXXX .

@entity1707 @entity14839 @entity857 @entity1423 @entity1674 @entity412 @entity10942 @entity731 @entity3645 @entity165
@entity731 was induced in 13 Yorkshire @entity1707 (4 weeks; 7-10 kg) by endothelial balloon denudation of the aorta and left anterior descending coronary artery and a diet containing 2% (wt/wt) of @entity165 , 8% (wt/wt) of lard fat and 0.5% (wt/wt) of @entity3645 . After 8 months 7 animals (group I) were sacrificed to determine the extent to which @entity731 had developed. The other 6 animals (group R) received a diet (no @entity165 , 5% (wt/wt) of lard fat and 5% (wt/wt) of fish oil) for 4 months. In I plasma @entity165 increased from 2.29 to 9.02 mmol l-1 after 8 months and in R it returned to 1.89 mmol l-1 after 12 months. Less marked changes occurred in plasma HDL @entity165 and @entity1674 . @entity857 -induced @entity1423 and the number of platelets remained constant in I whereas both parameters were reduced in R after 12 months. In the lesions of the abdominal aorta of I, @entity165 , @entity14839 , phospholipid and @entity412 contents were 4.97, 2.08, 4.20 and 0.77 micrograms g-1 wet wt, respectively, whereas in R these values (3.02, 0.47, 2.70 and 0.44 micrograms g-1 wet wt, respectively), were close to the values measured in non-abraded vessel wall specimens. The @entity10942 -positive area of the aorta was 34 +/- 9% in I and 10 +/- 4% in R (P less than 0.05). Luminal encroachment of the denudated left anterior descending coronary artery was 11 +/- 3% in I and 13 +/- 3% in R (P greater than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
