Effect of @entity219 on @entity224 -dependent XXXX radical production in vitro.

@entity1 @entity3625 @entity3624 @entity4259 @entity26 @entity219 @entity1792 @entity3787 @entity273 @entity920 @entity460 @entity224 @entity68
Trace elements play an important role in @entity26 metabolism and therefore in the formation of free radicals. Whereas @entity68 and @entity920 are usually the main enhancers of free radical formation, other trace elements, such as @entity219 and @entity4259 , protect against the harmful effects of these radicals. To investigate the different protective mechanisms of @entity219 on radical formation, we examined the effects of added @entity219 and @entity920 on @entity224 dismutase activity. We also studied the effects of @entity920 and @entity68 on @entity3624 oxidase activity and on the Haber-Weiss cycle ( @entity68 , @entity224 , and @entity273 ), which generates @entity3787 radicals in vitro. The @entity3625 / @entity3624 oxidase radical generating system contained a variety of different physiological ligands for binding the @entity68 . This study confirmed the inhibitory effect of @entity920 on @entity3624 oxidase activity. Moreover, it demonstrated that @entity219 inhibited @entity3787 radical formation when this formation was catalyzed by a @entity1792 - @entity68 complex in the @entity3625 / @entity3624 oxidase reaction. Finally, @entity1 blood plasma inhibited @entity1792 - @entity68 -dependent @entity3787 radical formation under the same conditions. Although trace elements seemed responsible for this antioxidant activity of plasma, it is likely that @entity219 played no role as a plasma antioxidant. Indeed, @entity460 appeared to be responsible for most of this effect under our experimental conditions.
