Detection of @entity3316 by capnography and its association with @entity519 in @entity1 undergoing sedation with XXXX .

@entity1 @entity3652 @entity515 @entity519 @entity3316 @entity544 @entity1363
OBJECTIVES: @entity3316 , a decrease in tidal volume without a change in respiratory rate, is not easily detected by standard monitoring practices during sedation but can be detected by capnography. Our goal was to determine the frequency of @entity3316 and its association with @entity519 in @entity1 undergoing sedation with @entity3652 . METHODS: @entity1 who received intravenous @entity3652 with or without @entity1363 for sedation in a pediatric emergency department were prospectively enrolled. Heart rate, respiratory rate, pulse oximetry, and end-tidal @entity544 (ET( @entity515 )) levels were recorded every 30 seconds. RESULTS: Fifty-eight subjects were included in this study. Fifty percent of subjects had recorded ET( @entity515 ) values less than 30 mm Hg without a rise in respiratory rate. Twenty-eight percent of subjects experienced a decrease in pulse oximetry less than 95%. @entity1 who experienced a persistent decrease in ET( @entity515 ) at least 30 seconds in length were much more likely to have a persistent decrease in pulse oximetry than those with normal or transient decreases in ET( @entity515 ) (relative risk, 6.6; 95% confidence interval, 1.4-30.5). Decreases in ET( @entity515 ) occurred on an average of 3.7 minutes before decreases in pulse oximetry. CONCLUSIONS: @entity3316 as detected by capnography is common in @entity1 undergoing sedation with @entity3652 with or without @entity1363 . @entity519 is frequently preceded by low ET( @entity515 ) levels. Further studies are needed to determine if the addition of routine monitoring with capnography can reduce the frequency of @entity519 in @entity1 undergoing sedation.
