Antibacterial effect of an herbal product persica on @entity2523 and XXXX : an in-vitro study.

@entity1 @entity1216 @entity527 @entity2521 @entity3841 @entity2523
OBJECTIVE: The plant Salvadora persica is used for oral hygiene in many parts of the world. It has been suggested that it has antibacterial properties, in addition to its ability to mechanically remove plaques. The aim of this study was to assess the antimicrobial activity of the herbal product Persica containing Salvadora persica against periodontopathogens @entity2523 and @entity3841 in vitro. MATERIALS AND METHODS: Fifty @entity1 with moderate and severe @entity2521 were recruited. Using paper points, @entity527 samples were taken from pockets with attachment loss >=  3mm. The samples were subjected to microbial culture to yield @entity2523 and A. actinomycetemcomitans. The ditch plate method was used for antimicrobial susceptibility testing of the bacteria to Persica compared to @entity1216 and distilled water. The growth inhibition zones of microorganisms around the ditches were measured in millimeters. The data were analyzed using SPSS 16. Freidman test and Wilcoxon signed ranks test with Bonferroni adjustment were used for analysis of variance with 5% significance level. P<0.05 for main comparisons and P< 0.017 for multiple comparisons were considered statistically significant. RESULTS: @entity2523 was sensitive to @entity1216 and persica. There was a significant difference (P=0.001) between antimicrobial activity of @entity1216 (mean 28.733mm, SD 5.216) and Persica (mean 16.333mm, SD 5.259) compared to water against @entity2523 . There was a significant difference (P< 0.001) between the antimicrobial activity of @entity1216 (24.045mm, SD 3.897) and Persica (0.545mm, SD 2.558) with respect to A. actinomycetemcomitans. There was no significant difference (P=0.317) between the antimicrobial activity of Persica and water against A. actinomycetemcomitans. CONCLUSION: The herbal product Persica had significant antimicrobial activity against @entity2523 and negligible antimicrobial activity against A. actinomycetemcomitans compared to 0.2% @entity1216 .
