Urea kinetics and @entity1568 appearance rates in @entity6 XXXX on peritoneal dialysis.

@entity1 @entity1568 @entity6 @entity1723 @entity3918
OBJECTIVE: We compared the relationship of protein intake (as measured by protein @entity1568 appearance) and dialysis delivery in insulin-dependent @entity6 ( @entity1723 ) and nondiabetic @entity1 . DESIGN: One to two 24-hour dialysate and urine collections were obtained in 20 @entity6 @entity1 and 42 nondiabetic @entity1 . The protein equivalent of @entity1568 appearance (PNA) was calculated by the Randerson formula. KT/V was determined using V obtained by the Watson formula. PNA was normalized using three different methods to determine body weight: first, by normal or ideal body weight according to the Metropolitan Table (nPNA); second, by standard body weight according to the NHANES Table (sPNA); and third, by V/0.58 (vPNA). RESULTS: The mean PNA was not different in @entity6 and nondiabetics (53 +/- 21 g/day vs 60 +/- 14 g/day), nor was weekly KT/V (2.1 +/- 0.6 vs 2.1 +/- 0.6). Mean normalized PNA was not different in @entity1723 versus non- @entity3918 regardless of the method. KT/V correlated with nPNA in @entity1723 (r = 0.54, p = 0.002 and non- @entity3918 , r = 0.31, p = 0.03), and with vPNA in @entity1723 (r = 0.73, p < 0.00001, and non- @entity3918 , r = 0.45, p = 0.0009). KT/V also correlated with sPNA in @entity1723 (r = 0.57, p = 0.001), but not in non- @entity3918 (r = 0.25, p = 0.08). The slope for normalized PNA versus KT/V was steeper for @entity1723 than for non- @entity3918 . CONCLUSION: KT/V and PNA are more closely correlated in @entity1723 @entity1 than in non- @entity3918 @entity1 . Thus it is extremely important that @entity1723 @entity1 receive an adequate level of dialysis.
