XXXX : racial and gender disparities in survival (1993 to 2002), stage and grade (1993 to 2007).

@entity1 @entity150 @entity5
PURPOSE: @entity150 survival is consistently lower in female and black @entity1 than in male and white @entity1 . We compared trends and differences according to clinical, demographic and facility characteristics by @entity1 race and gender to identify the impact of these characteristics on survival. MATERIALS AND METHODS: We identified @entity150 cases diagnosed in 1993 to 2007 from the National Cancer Data Base. Trends in grade and stage distribution between 1993 and 2007 were analyzed. Survival differences by race and gender were compared using 5-year relative survival and multivariate Cox regression. RESULTS: There were 310,257 white male, 102,345 white female, 13,313 black male and 7,439 black female @entity1 . Black and female @entity1 had a higher proportion of muscle invasive @entity5 than white and male @entity1 , and black @entity1 had a larger proportion of higher grade @entity5 . The incidence of stage 0a and of high grade @entity5 significantly increased with time. Multivariate analysis showed a significantly lower HR in white females than in white males (HR 0.9) but a significantly higher HR in black males and females (HR 1.2). The higher mortality risk in black males and females was primarily limited to late stage disease (HR 1.3). CONCLUSIONS: Survival differences by race and gender are partially explained by differences in @entity5 and demographic characteristics in black males and females, and fully explained by these characteristics in white females. Treatment delays and under treatment due to comorbid conditions, age and other factors may also contribute to these disparities.
