Ivy Sign on Fluid-Attenuated Inversion Recovery Images in Moyamoya Disease: Correlation with Clinical Severity and Old XXXX .

@entity1 @entity64 @entity63 @entity75 @entity7025
PURPOSE: Leptomeningeal collateral, in @entity7025 ( @entity7025 ), appears as an ivy sign on fluid-attenuated inversion-recovery (FLAIR) images. There has been little investigation into the relationship between presentation of ivy signs and old @entity75 . We aimed to evaluate clinical significance of ivy signs and whether they correlate with old @entity75 and the severity of clinical symptoms in @entity1 with @entity7025 . MATERIALS AND METHODS: FLAIR images of 83 @entity1 were reviewed. Each cerebral hemisphere was divided into 4 regions and each region was scored based on the prominence of the ivy sign. Total ivy score (TIS) was defined as the sum of the scores from the eight regions and dominant hemispheric ivy sign (DHI) was determined by comparing the ivy scores from each hemisphere. According to the degree of @entity63 , @entity1 were classified into four subgroups: 1) nonspecific symptoms without motor weakness, 2) single @entity63 ( @entity63 ), 3) recurrent @entity63 , or 4) @entity64 . RESULTS: TIS was significantly different as follows: 4.86  2.55 in @entity1 with nonspecific symptoms, 5.89  3.10 in @entity1 with single @entity63 , 9.60  3.98 in @entity1 with recurrent @entity63 and 8.37  3.39 in @entity1 with @entity64 (p=0.003). TIS associated with old lesions was significantly higher than those not associated with old lesions (9.35  4.22 vs. 7.49  3.37, p=0.032). We found a significant correlation between DHI and motor symptoms (p=0.001). CONCLUSION: Because TIS has a strong tendency with severity of @entity63 motor symptom and the presence of old lesions, the ivy sign may be useful in predicting severity of disease progression.
