Serum lactates are not predictive of XXXX severity in status I cardiac transplant candidates.

@entity1 @entity712 @entity296 @entity120 @entity880 @entity159 @entity922
BACKGROUND: Blood @entity880 is an accurate predictor of outcome in @entity922 @entity1 . However, its usefulness in status I heart transplant candidates with failing myocardium is largely unknown. The purpose of this study was to determine whether serum @entity880 levels are predictive of @entity712 severity in @entity159 cardiac transplant candidates. METHODS: Over a 6-month period, serial arterial serum @entity880 levels in 30 status I heart transplant candidates were measured. Measured serum @entity880 values (mmol/L) included the initial @entity880 level upon admission to the intensive care unit and the @entity880 level at 6-week intervals up to 24-weeks. Surveillance right heart catheterizations were also performed at 6-week intervals to determine pulmonary artery pressures and cardiac index. Baseline measurements were compared with the values obtained at time intervals of 6-, 12-, 18-, and 24-weeks. RESULTS: All status I heart transplant candidates were admitted to the intensive care unit for treatment of worsening @entity712 with intravenous inotropic therapy. All @entity1 had severe @entity120 (greater than two-thirds of systemic arterial pressure, mmHg) and/or severe low cardiac output state (cardiac index less than 2.0 L/min/M(2)). Admission @entity880 level was normal in all candidates. Intravenous inotropic therapy improved @entity1 ' symptoms and cardiopulmonary hemodynamic derangements although @entity880 levels remained within the normal range until the time of heart transplant operation or up to 24-weeks (p=NS). CONCLUSIONS: Blood @entity880 remains unaffected by worsening @entity712 of @entity296 @entity1 and is not predictive of @entity712 severity in status I cardiac transplant candidates.
