Morphological features correlation with serum XXXX markers in @entity263 .

@entity1 @entity263 @entity5 @entity1711 @entity6175 @entity2786 @entity420 @entity1486
OBJECTIVE: To find out Gleason grades, scores and to see the correlation of these morphological features with @entity5 markers in @entity263 . DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: The study was conducted at the Departments of Histopathology and Chemical Pathology, Armed Forces Institute of Pathology, Rawalpindi, over a period of one year. MATERIALS AND METHODS: Fifty cases of @entity263 were studied. Gleason grades and score of @entity5 were determined by doing @entity6175 and @entity1711 (HE) staining. Pre-operative serum prostatic acid phosphatase (PAP) and @entity1486 (PSA) assays were carried out in these cases. RESULTS: The @entity1 seen were between 50-102 years of age with an average of 70.9 years. There were 49 cases of @entity420 and 01 case of mixed adeno and transitional cell @entity263 . Twenty-eight (56%) @entity1 had Gleason score of 5-7. Twenty-nine (58%) @entity1 were having serum PSA levels between 10.0 ng/ml and 50.0 ng/ml. Thirteen (26%) cases showed PSA assays >50 ng/ml. The sensitivity of PSA test was 84 % in these cases. Thirty-five (70%) @entity1 were having PAP values >3.7 U/l (sensitivity 70 %). CONCLUSION: The Gleason grading system is a specific morphological predictor. The serum PSA showed better sensitivity and specificity with Gleason grades and scores as compared to serum @entity2786 . The serum PAP levels showed better correlation with morphological features as compared to serum PSA.
