Growth rate of 147 mammary XXXX .

@entity5 @entity1 @entity854 @entity189
In 147 cases of @entity189 , 388 serial mammographies were performed before final treatment. The average retrospective observation time was 27 months with a range of two months to 11 years. The number of serial mammographies per case ranged between two and 11. The @entity5 volume doubling times (TV); obtained by measuring the growth of the @entity5 nucleus shadow in the mammographies, ranged from 44 to 1869 days with an average of 212 days. No correlation between volume doubling time and histologic differentiation could be found. One hundred of these @entity5 @entity1 were found in a screening population of 22,000 @entity1 receiving serial mammographies in a time period ranging from two to 16 years. An additional 40 @entity5 @entity1 surfaced in this group without roentgenologic but with foregoing clinical or thermographic abnormalities before final diagnosis. An additional 21 @entity5 @entity1 surfaced without any @entity854 . The follow-up @entity5 ranged between three months and two years with a mean time of one year and nine months. Not considering @entity5 size, pathologic-thermographic signs appeared with greater frequency the faster the @entity5 grew. Theoretically, an average of more than 16 years should elapse before an initial @entity5 cell develops into a 10-mm primary @entity189 (30 doubling times). Therefore the length of time necessary for a 2-mm @entity5 to grow to a size of 10-mm is, on the average, four years.
