The distribution of interrenal stimulating activity in the brain of XXXX .

@entity1238 @entity1369 @entity1420 @entity228 @entity2819 @entity230
The stimulation of @entity228 release by the interrenal tissue of @entity1238 was investigated using an in vitro preparation of the interrenals and a radioimmunoassay for determinations of @entity2819 and @entity1369 in the perifusate. The stimulatory activity of four different areas was tested, the pars distalis, the post- and preoptic hypothalamus, and the cerebrum. It was found that besides the pars distalis, the post- and preoptic hypothalamus exhibit stimulatory activity on the interrenals. No such activity was found in the cerebrum. There was a decrease of activity found from the pars distalis to the postoptic and then to the preoptic part of the hypothalamus. The release of both @entity230 had different sensitivity. @entity1369 release was significantly elevated by all three different tissues, while the increase of the release of @entity2819 was only found significant in the case of stimulation by the pars distalis. The results also make clear that the increase of the release of @entity2819 is less than that of @entity1369 . The ratio of @entity2819 to @entity1369 decreased significantly after stimulation. This points to the fact that the rate of conversion of @entity2819 to @entity1369 (18-hydroxylation) is stimulated more than the production of @entity2819 from @entity1420 .
