[Evaluation of XXXX vessel of cerebral meningiomas with MR perfusion weighted imaging].

@entity1 @entity1653 @entity5
OBJECTIVE: To evaluate the potential roles of MR perfusion weighted imaging (PWI) in preoperative assessment of vascularity of @entity1653 . METHODS: 9 @entity1 with @entity1653 underwent conventional MR and PWI before operation (Grade I 32 cases, Grade II + III 7 cases). Immunohistochemical stain methods were used to quantitatively measure the microvessel density (MVD) values in @entity1653 after operation. The pulse sequence of PWI was single shot GRE-EPI-T2(*)WI, the cerebral blood volume (CBV) maps were calculated from the original data of perfusion images and the maximum CBV values of @entity1653 was acquired from CBV maps through measurement on the region of interest (ROI). The mean maximal relative cerebral blood volume (rCBV) values were calculated by dividing the maximum CBV of a @entity5 by that of the contralateral white matter. The differences of the mean maximal rCBV values between benign and malignant groups were analysed and commpared with the MVD values. RESULTS: The mean maximal rCBV values of benign and malignant groups were 9.76    4.68 and 3.57    0.27, respectively. The MVD values of benign and malignant groups were 22    12 and 11    5, respectively. The difference in mean maximal rCBV values between the two groups was statistically significant (t = 7.166, P < 0.01). Correlation analysis demonstrated that the mean maximal rCBV values and MVD values had significantly positive correlation (r = 0.715, P < 0.01). CONCLUSION: The mean maximal rCBV values are feasible for evaluation of microvessel angiogenesis of @entity1653 in vivo and useful for predicting @entity5 grade.
