Left ventricular mass and geometry and the risk of XXXX .

@entity1 @entity64 @entity1184 @entity4346 @entity385
BACKGROUND AND PURPOSE: @entity4346 ( @entity4346 ) is a risk factor for cardiovascular events, but its effect on @entity385 risk is established mainly in whites. The effect of LV geometry on @entity64 risk has not been defined. The aim of the present study was to evaluate whether @entity4346 and LV geometry are independently associated with increased @entity385 risk in a multiethnic population. METHODS: A population-based case-control study was conducted on 394 @entity1 with first @entity385 and 413 age-, sex-, and race-ethnicity-matched community control subjects. LV mass was measured by transthoracic echocardiography. LV geometric patterns (normal, concentric remodeling, concentric or @entity1184 ) were identified. @entity64 risk associated with @entity4346 and different LV geometric patterns was assessed by conditional logistic regression analysis in the overall group and age, sex, and race-ethnic strata, with adjustment for established @entity64 risk factors. RESULTS: @entity1184 carried the greatest @entity64 risk (adjusted odds ratio [OR], 3.5; 95% confidence interval [CI], 2.0 to 6.2), followed by @entity1184 (adjusted OR, 2.4; 95% CI, 2.0 to 4.3). Concentric remodeling carried slightly @entity64 risk (adjusted OR, 1.7; 95% CI, 1.0 to 2.9). Increased LV relative wall thickness was independently associated with @entity64 after adjustment for LV mass (OR, 1.6; 95% CI, 1.1 to 2.3). CONCLUSIONS: @entity4346 and abnormal LV geometry are independently associated with @entity64 risk. @entity4346 is strongly associated with @entity385 in all age, sex, and race-ethnic subgroups. Increased LV relative wall thickness imparts an @entity64 risk after adjustment for LV mass and is of additional value in @entity64 risk prediction.
