Hemodynamic Differences Between Ruptured and Unruptured XXXX Simultaneously Existing in the Same Location: 2 Case Reports and Proposal of a Novel Parameter Oscillatory Velocity Index.

@entity1 @entity548 @entity510 @entity1756 @entity397 @entity439 @entity438
BACKGROUND: Studies have demonstrated certain hemodynamic characteristics featuring the @entity397 status of @entity438 using computational fluid dynamics. These studies were conducted based on the comparison of a large number of ruptured and @entity439 . However, not only @entity439 size and location but also perianeurysm environment, such as @entity548 and intracranial pressure, affect hemodynamic changes. We hypothesized that a case in which ruptured and unruptured @entity438 simultaneously exist in the same location would be an ideal model to demonstrate hemodynamic characteristics of the @entity397 status. CASE DESCRIPTION: We report 2 rare cases with @entity510 , each of which involved 2 @entity439 at the common parent artery. One @entity1 had 2 anterior communicating @entity438 , and the other @entity1 had 2 middle cerebral @entity438 . Preoperative morphologic and hemodynamic examinations were performed to diagnose the @entity397 status of the 2 @entity439 , and each ruptured @entity439 was then confirmed during surgical clipping. Morphologic evaluation revealed higher shape indexes in both @entity1756 . Lower wall shear stress, wall shear stress gradient, and @entity439 formation indicator were observed in both @entity1756 . In contrast, @entity1756 had a higher oscillatory shear index and oscillatory velocity index, which was the novel hemodynamic parameter to quantify the fluctuation of flow velocity vector. CONCLUSIONS: Quantitative characterization of the hemodynamic environment can distinguish the @entity397 status by using appropriate models minimizing certain bias caused by @entity510 and @entity439 location.
