Relationship between XXXX and long-term mortality in general surgery: a prospective follow-up study.

@entity1 @entity102 @entity281 @entity580 @entity204
A prospective study of 1431 @entity1 admitted to a general surgery department were followed up for a median of 6.2 years after discharge (7679 @entity1 -years of follow-up). We collected information on underlying conditions, including severity of illness, and healthcare-related variables. Relative rates of @entity204 and their 95% confidence interval (CI) were estimated using @entity1 -years as the denominator. Multiple-risk factors adjusted for relative rates (RR) were obtained using Poisson regression analysis. There were 172 deaths during the follow-up period after hospital discharge (2/100 @entity1 -years). Follow-up was complete in 91% of the cohort. There were no important differences in demographic characteristics or risk factors between @entity1 followed up and those lost to follow-up. The @entity204 rate in @entity1 with any @entity580 was 5.3/100 @entity1 -years, and the relative rate was 3.07 (95% CI: 2.20-4.24). After adjusting for the main predictors of mortality, we found an effect modification by the presence of @entity102 (P = 0.01 for the product-term between @entity580 and the diagnosis of @entity102 ). Among @entity1 without any underlying @entity102 , @entity580 was related to a significantly higher long-term mortality (RR = 2.47, 95% CI: 1.24-4.91). In these @entity1 , surgical wound @entity281 yielded a RR of mortality of 3.44 (95% CI: 1.63-7.27). Among @entity1 with underlying @entity102 no association between @entity580 and long-term mortality was found. No evidence of an important modification of the relative rate along the follow-up period was observed. In conclusion surgical @entity1 without @entity102 developing @entity580 have an increased risk of long-term mortality.
