Interstitial implant with XXXX .

@entity5 @entity1 @entity221
A Phase I Pilot Study combining interstitial or intracavitary irradiation using 192Ir or 137Cs and @entity221 in advanced or recurrent @entity5 is underway at the City of Hope National Medical Center. @entity221 is performed using 0.5 megahertz RF (500 kilohertz) radiofrequency localized current fields. In the implanted volume, a temperature of 41 degrees to 45 degrees C is maintained for 30 to 40 minutes. @entity221 is performed prior to irradiation in all @entity1 . All @entity1 had either failed previous conventional treatments, including surgery, chemotherapy and/or radiation therapy, or had advanced @entity5 which were not felt to be controllable by conventional means. Sixteen lesions were implanted in 15 @entity1 . Of the 16 lesions, 11/16 (68%) achieved complete response, and three had no response or recurred locally. The six @entity1 (100%) receiving interstitial implant and @entity221 as the primary therapy achieved complete response. Normal tissue complications were minimal. Range of response was three to 13 months. Interstitial thermoradiotherapy appears to be a safe and promising mode of therapy in advanced or recurrent accessible @entity5 .
