[Elective radiotherapy in XXXX ].

@entity1 @entity0 @entity5 @entity204 @entity34
From March 1972 to November 1979 a total of 157 @entity1 with stage I to III primary @entity0 have been irradiated after segmental resection (12 cases), tilectomy (89 cases) or biopsy (56 cases). Complete local control was achieved in all Stage I lesions, in 97% of @entity34 and in 68% of @entity5 . Non recurrence has been observed in @entity1 previously operated by segmental resections, while local failures occurred in 6/89 and in 16/56 @entity1 operated by tilectomy or biopsy, respectively. Of the 28 Stage I @entity1 , 24 (86%) are alive, one with distant metastases. Four @entity1 of this group are dead, 2 of intercurrent disease and 2 of @entity0 . Of the 61 (Stage II) @entity1 , 38 (62%) are alive, 5 of these with distant metastases. Twenty-three @entity1 are dead, 15 with active disease, and 8 suffered intercurrent @entity204 . Of the 68 Stage III @entity1 , 21 (31%) are alive, 6 of these with distant metastases. Fourty-seven @entity1 are dead, 43 of @entity0 and 4 of intercurrent disease. The high probability of initial subclinical deposits is evidenced by the fact that 49 of the 68 @entity1 in this group developed distant metastases. The @entity1 with T1 lesions appear to comprise the most favourable group with a relapse free survival at five years of 76%. The 5 years relapse free survival was 62% for T2 lesions and 25% for T3 and T4 lesions. N0 status does not confer the same favourable prognosis as T1 status. N+ status, however, resulted in a definitely negative prognostic factor. Cosmetic results after our treatment approach appear to be extremely good. A marked difference between the irradiated and controlateral breast occurred only in 10 of the 125 @entity1 after a minimum of 2 years observation.
