Correlation between the XXXX -r-lyase (CES) and the severity of peptic ulcer disease.

@entity3958 @entity1 @entity3959 @entity1534 @entity3957 @entity2275
BACKGROUND: The infection of @entity1534 ( @entity1534 ) is one of the most important causes of @entity2275 . The role of @entity3957 ( @entity3958 ) production in @entity1534 -induced @entity2275 . AIM: The expression of @entity3959 -y-lyase (CSE) was determined, and correlated with the severity of @entity2275 . METHODS: One hundred and eight @entity1 were selected based on the determination of @entity2275 and the infection of @entity1534 ( @entity1534 ), including 36 normal control, 36 @entity1 with @entity1534 -negative @entity2275 , and 36 @entity1 with @entity1534 -positive @entity2275 . RT-PCR determination was performed to determine the expression of CSE, NF-kB and IL-8. RESULTS: The expression of CSE, NF-kB and IL-8 was higher in the @entity2275 group than control group (p<0.05). Compared with the @entity1534 -negative @entity2275 , the expression of CSE, NF-kB and IL-8 was higher than @entity1534 -positive @entity2275 group (p<0.05). For @entity1534 -negative @entity2275 group, the expression of CSE positively correlated with the expression of NF-kB (r=0.98, p<0.05) and IL-8 (r=0.95, p<0.05). For @entity1534 -positive @entity2275 group, the expression of CSE also positively correlated with the expression of NF-kB (r=0.99, p<0.05) and IL-8 (r=0.85, p<0.05). CONCLUSION: The expression of CSE was positively correlated with the severity of @entity2275 .
