Prognostic factors in XXXX .

@entity1 @entity0 @entity5 @entity189 @entity513 @entity3558 @entity3
Two hundred seven mucinous @entity0 were morphologically classified into two different groups: pure @entity189 consisting only of areas with small epithelial islands of solid @entity5 floating in abundant extracellular @entity3558 , and mixed @entity189 where the @entity5 contains large areas of @entity3558 , as well as areas with infiltrating @entity189 devoid of extracellular @entity3558 . Of the 207 @entity5 , 95 were of the pure type and 112 of the mixed type. The pure and mixed @entity189 differed significantly with respect to a number of prognostic factors, the most important of which was lymph node status. @entity1 with pure @entity189 had significantly fewer lymph node @entity3 at the time of primary operation (P = 0.0001) and a significantly longer recurrence-free survival (P = 0.03) than @entity1 with mixed @entity189 . @entity1 with mixed @entity189 closely resembled @entity1 with @entity513 not otherwise specified (NOS) with respect to both lymph node status and recurrence-free survival. In multivariate analysis, the single most important factor for predicting recurrence-free survival among the 207 @entity1 was lymph node status. However, of 94 pure @entity189 , only 6 had lymph node @entity3 at the time of mastectomy. A detailed morphologic analysis demonstrated that two of these six cases were incorrectly diagnosed as being pure @entity189 --they were actually of the mixed type. In another two of these cases, the @entity3 originated from a co-existent infiltrating @entity513 . Thus, @entity3 to the regional lymph nodes were observed in only two cases of pure @entity189 . It is concluded that the biologic behavior of the pure @entity189 differs from that of both the mixed @entity189 and @entity513 NOS. Thus, a new definition is suggested, in which a @entity189 is classified as such only if it is a pure @entity189 , and mixed @entity189 are classified according to the component without extracellular @entity3558 production.
