Central corneal thickness and intraocular pressure in a Nepalese population: the Bhaktapur XXXX Study.

@entity1 @entity735 @entity726
PURPOSE: The purpose of the study was to evaluate the characteristics of central corneal thickness and its association with age, sex, and intraocular pressure in a Nepalese population. @entity1 AND METHODS: The study design was a cross-sectional, population-based survey. Two thousand three hundred thirty @entity1 aged 40 years and older were examined at Tilganga Institute of Ophthalmology, a @entity735 centre in Kathmandu, Nepal. All @entity1 underwent a complete ophthalmic examination that included measurements of central corneal thickness with an ultrasonic pachymeter and intraocular pressure with a Goldman type applanation tonometer. RESULTS: The main outcome measures were central corneal thickness and intraocular pressure. Mean age of the 2330 @entity1 examined was 51.3 years (SD  9.56). The mean central corneal thickness and mean intraocular pressure was 539.10  m (SD  33.73) and 13.33 mm Hg (SD  2.26), respectively. Central corneal thickness showed an average decrease of 2.67  m (95% confidence interval, 2.21-4.1) per decade increase in age. A 100  m increase in central corneal thickness was associated with a 1.03 mm Hg (95% confidence interval, 0.79-1.26) increase in intraocular pressure after adjusting for age and sex. CONCLUSIONS: The changes in central corneal thickness values cause a significant variation in intraocular pressure in this population, suggesting that measurement of central corneal thickness will have implications in the diagnosis and management of @entity726 .
