Treatment of XXXX --factors associated with fatal outcome.

@entity1 @entity1955 @entity772 @entity204 @entity1954
Treatment of @entity772 has been associated with a high mortality. The causes of @entity204 were analysed in this paper by retrospective study of the records of 11 @entity772 patients. The serum @entity1955 (T4) and @entity1954 (T3) levels were estimated retrospectively from the amounts of hormone given to the @entity1 by a two-compartment model. Seven @entity1 died and 4 survived. The @entity1 who died were significantly older (78.9 +/- 2.2 years, mean +/- SEM) than those who survived (66.8 +/- 3.7 years). The initial heart rate was lower in the decreased group, but both groups had increased their heart rate on treatment. The surviving @entity1 showed an increase in body temperature during the first 3 days of treatment, in contrast to the @entity1 who eventually died. The deceased @entity1 had received larger amounts of thyroid hormone and had calculated levels of T3 that were nearly twice as high as those of the surviving @entity1 . Old age and a high serum level of T3 are determinants for the fatal outcome of @entity772 . Our analysis underscores the importance of using a cautious replacement regimen in @entity772 @entity1 .
