Development of a conceptual framework of health-related quality of life in locally recurrent XXXX .

@entity5 @entity1 @entity458
BACKGROUND: The surgical management of locally recurrent @entity5 (LRRC) has become widely accepted to afford cure and improve quality of life in this subset of @entity1 . Thus far, traditional surgical and oncological markers have been used to highlight the success of surgical intervention. The use of @entity1 reported outcomes, specifically health-related quality of life (HRQoL) is sparse in these @entity1 . This maybe in part due to the lack of well-designed, validated instruments. AIM: The study identifies HRQoL issues relevant to @entity1 undergoing surgery for LRRC, with an aim to develop a conceptual framework of HRQoL specific to LRRC to enable measurement of @entity1 reported outcomes in this cohort of @entity1 . METHODS: Qualitative focus groups were undertaken at two institutions to identify relevant HRQoL themes. The principles of thematic content analysis were used to analysis data. NViVo10 was used to analyse data. RESULTS: Twenty-one @entity1 participated in six consecutive focus groups. Two patterns of themes emerged related to HRQoL and healthcare services delivery and utilisation. Identified themes related to HRQoL included symptoms, @entity458 , role and social functioning, future perspective. Under healthcare services and delivery and utilisation the subdomain of disease management, treatment expectations and healthcare professionals were identified. CONCLUSION: This is the first qualitative study undertaken exclusively in @entity1 with LRRC to ascertain relevant HRQoL outcomes. The impact of LRRC on @entity1 is wide-ranging and extends beyond traditional HRQoL outcomes. The study operationalises the identified outcomes into a conceptual framework, which will provide the basis for the development of a LRRC specific @entity1 reported outcome measure. This article is protected by copyright. All rights reserved.
