Routine modified D2 lymphadenectomy performance in pT1-T2N0 XXXX .

@entity1 @entity356 @entity13425
AIM: To evaluate routine modified D2 lymphadenectomy in @entity356 , based on immunohistochemically detected @entity13425 micrometastases in level II lymph nodes. METHODS: Among 95 @entity356 @entity1 who were routinely submitted to curative modified D2 lymphadenectomy, from January 2004 to December 2008, 32 were classified as pN0. All level I lymph nodes of these 32 @entity1 were submitted to immunohistochemistry for micrometastases detection. @entity1 in whom micrometastases were detected in the level I lymph node stations (n = 4) were excluded from further analysis. The level II lymph nodes of the remaining 28 @entity1 were studied immunohistochemically for micrometastases detection and constitute the material of the present study. RESULTS: @entity13425 micrometastases in the level II lymph nodes were detected in 14% (4 out of 28) of the @entity1 . The incidence was further increased to 17% (4 out of 24) in the subgroup of T1-2 @entity356 @entity1 . All micrometastases were detected in the No. 7 lymph node station. Thus, the disease was upstaged from stage IA to IB in one @entity1 and from stage IB to II in three @entity1 . CONCLUSION: In @entity356 , true R0 resection may not be achieved without modified D2 lymphadenectomy. Until D2+/D3 lymphadenectomy becomes standard, modified D2 lymphadenectomy should be performed routinely.
