Correlation of serum neutrophil gelatinase associated lipocalin with disease severity in XXXX .

@entity1 @entity101 @entity1133 @entity409 @entity1458 @entity1011 @entity15901 @entity414
BACKGROUND: Vascular @entity409 is considered central to the pathogenesis of @entity101 ( @entity101 ). Serum level of @entity15901 ( @entity15901 ) is closely related to endothelial injury. The aim of this study was to examine the correlation of serum @entity15901 with disease severity in @entity101 . MATERIALS AND METHODS: This prospective case-control study was carried out for one year. After informed consent, ethical clearance, total 1,850 pregnant @entity1 were screened. Analysis was performed on 142 cases of @entity101 and 31 healthy controls. Quantitative measurement of serum @entity15901 levels was done by the enzyme linked immunosorbent assay (ELISA) technique, by using sandwich ELISA kit. RESULTS: Mean serum @entity15901 value in @entity1 with @entity1458 was significantly higher when compared with non-oliguric @entity1 (P < 0.001). Serum @entity15901 had a positive correlation with systolic blood pressure (r ~ 0.5973), diastolic blood pressure (r ~ 0.6195), blood @entity1133 (r ~ 0.4392), serum @entity1011 (r ~ 0.6112), serum @entity414 (r ~ 0.3878). Sensitivity and specificity of serum @entity15901 using a cut-off value of 545 pg/ml, for the diagnosis of @entity101 , was 97.89% and 93.55% respectively, using 95% confidence interval. CONCLUSION: Between the two groups, we found that serum @entity15901 had a positive correlation with disease severity and better sensitivity and specificity in the evaluation of @entity101 .
