Electrochemotherapy in advanced XXXX and cutaneous @entity3 - a retrospective multicenter analysis.

@entity1 @entity0 @entity706 @entity242 @entity5 @entity1489 @entity957 @entity548 @entity189 @entity3 @entity320
BACKGROUND AND OBJECTIVES: Once classic treatments such as chemotherapy or radiation therapy have been exhausted, only few therapeutic options remain for extensive @entity1489 or cutaneous @entity3 . In such cases, electrochemotherapy may be considered as alternative therapy. @entity1 AND METHODS: In this retrospective study, clinical features, treatment response, and adverse effects were evaluated in 56 @entity1 treated with electrochemotherapy at six German dermatology departments. RESULTS: The mean age of the @entity1 cohort (14 @entity1 , 42 @entity1 ) was 69.3 years. Included were 20 @entity1 with skin metastasis of advanced @entity320 , 13 @entity1 with @entity0 @entity3 , 15 @entity1 with primary @entity957 or cutaneous @entity3 of other @entity189 types, and 8 @entity1 with @entity706 or @entity242 . The overall response rate was 44.6% (10.7% complete response; 33.9% partial response). By contrast, 31 (55.4%) @entity1 did not respond (12.5% had stable disease; 42.9%, @entity5 progression). @entity1 with @entity320 and @entity706 or @entity242 responded significantly better than those with @entity189 . Roughly one quarter of @entity1 showed an improvement in @entity5 -related exudation, fetor, and @entity548 . CONCLUSION: Showing only few adverse effects, electrochemotherapy was effective in about one half of the @entity1 with advanced @entity5 . Treatment response appears to depend on the @entity5 entity.
