Age trajectories of XXXX case fatality: leveling off at the highest ages.

@entity1 @entity64
BACKGROUND: Mortality rates level off at older ages. Age trajectories of @entity64 case-fatality rates were studied with the aim of investigating prevalence of this phenomenon, specifically in case-fatality rates at older ages. METHODS: A registry of all hospitalized @entity64 @entity1 in Denmark included 40,155 @entity1 with evaluations of @entity64 severity, computed tomography, and cardiovascular risk factors. Data on mortality were used to construct age trajectories of 3-day, 1-week, 1-month, and 1-year case-fatality rates in @entity1 and @entity1 . RESULTS: Of the 40,155 @entity1 , 19,301 (48%) were @entity1 (mean age, 74.5 years) and 20,854 (52%) were @entity1 (mean age, 69.7 years). In both @entity1 and @entity1 , 3-day case-fatality rates leveled off, beginning in the @entity1 ' mid-70s. In @entity1 , 1-week case-fatality rates leveled off further in their early 80s, whereas in @entity1 , 1-week case-fatality rates accelerated with age. One-month and 1-year case-fatality rates accelerated with age for both sexes. CONCLUSIONS: It is an apparent paradox that case-fatality rates in the acute state of @entity64 level off at the highest ages. Heterogeneity, innate or acquired, in regard to survival capacity may explain the phenomenon.
