Statin Use Is Associated with @entity2336 Syndrome/ XXXX : A Population-Based Case-Control Study.

@entity239 @entity308 @entity101 @entity6 @entity301 @entity28 @entity4697 @entity566 @entity409 @entity2371 @entity565 @entity2336 @entity2704 @entity1744 @entity46 @entity5815 @entity10632 @entity2335 @entity6817
INTRODUCTION: @entity6817 may induce @entity409 of the bladder urothelium. Epithelial dysfunction was proposed as one of the major potential etiologies for @entity2336 syndrome/ @entity2335 (BPS/IC). In this study, we examined the association between statin use and BPS/IC using a population-based study. SUBJECTS AND METHODS: This case-control study used the Taiwan Longitudinal Health Insurance Database. In total, 815 female subjects with BPS/IC and 4075 randomly selected female controls were included. We used a conditional logistic regression to compute the odds ratio (OR) for having previously used statins between cases and controls. RESULTS: A conditional logistic regression analysis showed that the OR of prior statin users for cases was 1.52 (95% confidence interval (CI): 1.19-1.94) compared to controls after adjusting for @entity6 , @entity101 , @entity301 , @entity28 , chronic @entity2371 , @entity1744 , @entity239 , @entity5815 , @entity308 , @entity4697 , @entity2704 , @entity10632 , @entity566 , @entity46 , and @entity565 . Furthermore, adjusted ORs of regular and irregular statin use for cases were 1.58 (95% CI: 1.20-2.08) and 1.53 (95% CI: 1.02-2.31), respectively, compared to controls. CONCLUSION: We concluded that there was an association between statin use and BPS/IC.    2015 S. Karger AG, Basel.
