Individualised dialysate temperature improves intradialytic haemodynamics and abrogates haemodialysis-induced XXXX , without compromising tolerability.

@entity1 @entity2033 @entity551 @entity1562 @entity204 @entity65
BACKGROUND/AIMS: Haemodialysis-induced @entity1562 is associated with @entity551 , increased likelihood of @entity65 and @entity204 . Dialysis at 35  C reduces stunning, but adverse thermal symptoms limit technique adoption. This study investigated whether individualised body temperature dialysis improves haemodynamic stability and abrogates stunning. METHODS: Randomised crossover study of 11 @entity1 compared LV regional wall motion abnormalities (RWMAs) at 37  C ( @entity2033 (37)) and body temperature ('individualised', @entity2033 (ind)). Regional systolic function was quantitatively assessed by echocardiography. Haemodynamics were assessed using continuous pulse wave analysis. Thermal symptoms were scored by questionnaire. RESULTS: Mean predialysis body temperature was 36.0    0.1  C. Mean number of peak stress RWMAs per @entity1 was lower with @entity2033 (ind) (3.9    1.4 vs. 5.3    1.5, p = 0.03). Intradialytic systolic BP was higher during @entity2033 (ind) versus @entity2033 (37) (p < 0.001). Individualised body temperature dialysis demonstrated symptomatic tolerability comparable to @entity2033 (37). CONCLUSIONS: Individualised-temperature haemodialysis abrogates stunning, providing effective haemodynamic stabilisation at no additional therapy cost.
