@entity500 or @entity4446 before colectomy for XXXX is not associated with @entity260 .

@entity1 @entity500 @entity254 @entity31 @entity260 @entity4446 @entity230 @entity288
AIM: To determine whether the use of @entity500 / @entity4446 before colectomy is associated with an increased rate of @entity260 . METHODS: All @entity1 who underwent colectomy with ileal pouch-anal @entity254 for @entity31 between 1997 and 1999 were identified. Medical records were abstracted for demographics, extent and duration of disease, dose and duration of @entity288 and @entity500 / @entity4446 , albumin, and Truelove/Witts score. Early (30-day) and late (6-month) complications were identified. Noncorticosteroid immunosuppressive use was coded as none, @entity500 / @entity4446 within 1 week of surgery, or therapy with other immunosuppressive agents within 1 month of surgery. A logistic regression analysis assessed the association between these variables and complications. RESULTS: Early complications occurred in 49 of 151 (32%) @entity1 not treated with immunosuppressive agents, 12 of 46 (26%) @entity500 / @entity4446 -treated @entity1 , and 4 of 12 (33%) @entity1 treated with other immunosuppressive agents (p = 0.71). Late complications occurred in 72 of 148 (49%), 20 of 46 (43%), and 8 of 12 (67%) @entity1 in these same groups, respectively. Intravenous or oral @entity230 at doses of 40 mg/d or greater (p < 0.01) and severe or fulminant disease (p = 0.0094) were associated with greater early complication rates. CONCLUSION: Early complications after restorative proctocolectomy for @entity31 are associated with high dose @entity230 and severe disease but not use of @entity500 / @entity4446 .
