[Changes of thyroid function, thyroid antibodies and urinary XXXX among permanent residents of Urumqi in Xinjiang].

@entity1 @entity1375 @entity1496 @entity1955 @entity1378 @entity3214 @entity1954 @entity1374
OBJECTIVE: To understand the rates of diagnosis on @entity1374 and the differences in the distribution of age groups among those permanent residents, to analyze the relationships among thyroid function, thyroid antibodies and urinary @entity1496 . METHODS: A cross-sectional survey was performed in 1 995 permanent residents in Urumqi, Xinjiang in May, 2013, Among them, 1 906 were healthy adults aged 18-84 age, with mean age as (46.3    14.2) years and 30.4% of them were @entity1 . One time 10 ml random urine and blood samples were drown to examine urinary @entity1496 (UI) thyroid stimulating hormone (TSH), free @entity1955 (FT4), free @entity1954 (FT3), anti-thyroglobulin (TgAb) and anti-thyroid peroxidase (TPOAb). RESULTS: 1) 213 residents were newly diagnosed as having @entity1374 (11.2%, including 78.4% @entity1 ), @entity1378 (clinical and @entity1378 ) that accounted for 2.7%, @entity1375 (clinical and @entity1375 ) was accounted for 8.5%. Positive rates of TgAb (23.2%), TPOAb (16.6%) were noticed. The median urinary @entity1496 was 134.5   g/L, with 32% of the subjects were having @entity1496 deficiency, 58% having adequate @entity1496 and another 10% as under excessive @entity1496 . No differences were observed on urine @entity1496 between @entity1374 and @entity3214 or between subjects with positive and negative antibodies. 2) TSH appeared different among age-groups of 18-, 45- and over 60. TSH showed higher in @entity1 than in @entity1 , with P value as < 0.001. For @entity1 with @entity3214 , TSH level in the antibody positive group was significantly higher than the antibody negative group (P < 0.000 1). 3) For @entity1 over 60 of age, morbidity of @entity1375 was significantly higher than those under 60 but with no differences related to @entity1378 or the antibody positive rate. CONCLUSION: UI levels were not significantly related with thyroid function and thyroid antibodies among residents of Urumqi, @entity1 showed higher on @entity1374 or the rate of positive antibody. In the antibody positive group, TSH levels were significantly higher than in the antibody negative group. @entity1375 was seen higher in the over 60-years-of-age population. Monitoring programs on thyroid function, thyroid antibodies and urinary @entity1496 among @entity1 over 60-years-of-age, should be strengthened.
