The Spectrum of Kidney Pathology in XXXX / @entity1072 : A 25-Year Multicenter Experience.

@entity1 @entity8 @entity2783 @entity14033 @entity1072 @entity1503 @entity1892 @entity1986 @entity1985 @entity631
BACKGROUND: @entity1072 and @entity1072 are 2 different presentations of the most common @entity1892 in western countries ( @entity1072 ). In this disease, @entity8 is usually silent, and is rarely reported in the literature. This study provides a clinicopathological analysis of all-cause @entity8 in @entity1072 @entity1 . METHODS: Fifteen @entity1072 @entity1 with kidney biopsy were identified retrospectively. Demographic, clinical, pathological and laboratory data were assessed at biopsy, and during follow-up. RESULTS: At biopsy 11 @entity1 presented @entity8 , 7 @entity1 @entity1985 , 6 @entity1 dysproteinemia, and 3 @entity1 @entity14033 . Kidney pathology revealed @entity1072 -specific monoclonal infiltrate in 10 biopsies, @entity8 in 9 biopsies (5 membranoproliferative @entity631 , 2 minimal change disease, 1 @entity631 with organized microtubular monoclonal immunoglobulin deposits, 1 @entity2783 ). Five @entity1 presented @entity1986 attributed to @entity1072 . After treatment of the @entity1503 , improvement of renal function was observed in 7/11 @entity1 , and remission of @entity1985 in 5/7 @entity1 . During follow-up, aggravation of the @entity8 systematically occurred in the absence of favorable response to hematological treatment. CONCLUSIONS: A broad spectrum of @entity8 is associated with @entity1072 . In this setting, kidney biopsy can provide important information for diagnosis and therapeutic guidance.
