[The Spanish Society of Paediatric Infectious Diseases (SEIP) recommendations on the diagnosis and management of XXXX ].

@entity1 @entity7408 @entity7409 @entity5132 @entity281 @entity364 @entity3 @entity580 @entity1292 @entity375
Candida @entity375 are ubiquitous commensals, which can cause @entity1292 in any location of the body. The source of @entity281 may be both endogenous and exogenous. @entity3 encompasses different entities ranging from @entity3 to disseminated @entity281 . @entity3 is the third leading cause of nosocomial bloodstream @entity281 and the fourth of all @entity580 . It is also the most common invasive @entity364 in non-neutropenic critically ill @entity1 , with a remarkable increase in the last 20 years owing to the increased survival of these @entity1 and to more complex diagnostic, therapeutic and surgical procedures. Its incidence in @entity1 , according to recent reviews, stands at 38.8 cases/100,000 @entity1 younger than 1 year. @entity5132 remains the most frequent isolate in invasive @entity281 , although @entity281 caused by other species have risen in the last years, such as C. kruzsei, @entity7408 and @entity7409 ; the latter causing @entity3 mainly associated with central venous catheter management, especially in neonatal units. The overall mortality of @entity3 is high, with 30-day mortality reaching 20-44% in some series involving paediatric @entity1 . This report provides an update on incidence, epidemiology, clinical presentation, diagnosis, treatment and outcome of invasive @entity281 by Candida spp. in the paediatric @entity1 .
