Hyperintensity on diffusion weighted image along ipsilateral cortical spinal tract after cerebral XXXX : a diffusion tensor analysis.

@entity1 @entity4798 @entity64 @entity1188 @entity6441 @entity717 @entity385
PURPOSE: Hyperintensity along the ipsilateral cortical spinal tract (CST) on a diffusion weighted imaging (DWI) has been reported to may be associated with @entity717 after @entity4798 and can be misdiagnosed as a new @entity1188 . However, the underlying patho-physiology related to this finding is not clear. The goal of our study was to analyze the diffusion tensor imaging (DTI) changes in @entity1 with this hyperintensity. MATERIALS AND METHODS: Eight @entity1 (50    10 years) who exhibited hyperintensity on DWI along ipsilateral CST from 3 to 21 days after @entity64 onset were reviewed as positive group, including 5 @entity1 with serial DTI examinations. Twelve @entity1 without hyperintensity during the matched examination time were classified as reference group. The apparent diffusion coefficient (ADC), fractional anisotropy (FA), and eigenvalues and their ratios (ipsilateral/contralateral value) in cerebral peduncle were measured, their correlation with motor function scale at eight months after @entity64 onset were evaluated. RESULTS: The serial examinations showed that hyperintensity could eventually disappear. Both the ipsilateral ADC and FA values were significantly decreased (p<0.05) compared to the contralateral side. The ipsilateral FA significantly correlated with motor function scale in both groups (r = 0.875, 0.738; p = 0.004, 0.006 respectively). CONCLUSIONS: The hyperintensity on DWI is a transient pathological process of @entity6441 after @entity385 , its diffusion characteristics include concurrent significant decrease of ipsilateral ADC and FA. The ipsilateral FA value has the potential to predict neurological motor function outcome in such @entity1 .
