The gut origin septic states in blunt XXXX (ISS = 40) in the ICU.

@entity11727 @entity1 @entity295 @entity1503 @entity281 @entity1230
The association between support elements (ventilator days = Vd, enteral protein = EnP, number of antibiotics per day = AB/d) and the magnitude of the septic state ( @entity11727 ) and its bacteriologic manifestations (bacti. log) in 66 @entity1 with blunt @entity1230 (mean HTI-ISS = 40) over 1649 days have been studied retrospectively. @entity11727 is measured by summing the standard deviation units of change in the septic direction for the 16 measurements taken every day in the intensive care unit. Increasing Vd is tightly associated with an increasing @entity11727 (r = +0.52), after day 10 an increasing bacti. log (r = +0.21 to +0.32), and an increasing AB/d (r = +0.26) (all p less than 0.001, N = 1615 - 1626). The independent variables that best predicted Vd were delayed operations (DORS), day of rising EnP, and @entity1503 ( @entity1503 ) (adj. R sq. = 0.84, F = 104, dF = 3/59). An increasing AB/d was associated with an increasing @entity11727 (r = +0.38), increasing Vd (r = +0.26), and an increased bacti. log (r = +0.14 to +0.18) (all p less than 0.001, N = 1615). Only an increased EnP was consistently associated with a reduced @entity11727 (r = -0.38) and a reduction in bacti. log (r = -0.10 to -0.21) (all p less than 0.001, N = 1626-1636). The independent variables Vd, EnP, AB/d, and @entity1503 best predicted @entity11727 for all surviving @entity1 (adj. R sq. = 0.42, F = 268, dF = 4/1496). The @entity1 who died of @entity295 were not different in terms of bacti. log from those with equal Vd but were distinguished by zero EnP, high AB/d, and persistent ventilatory support. In conclusion, DORS is tightly associated with increased Vd, @entity11727 , AB/d, and zero EnP. If Vd exceeds 10, there is an increasing bacti. log and evidence of @entity281 probably from the gut. This responds only to increased EnP and not to AB/d. Death due to @entity295 is not associated with increased bacti. log but with zero EnP and high AB/d and their consequences.
