Five-year longitudinal bone evaluations in individuals with chronic complete XXXX .

@entity1 @entity1688 @entity79 @entity1566 @entity451
BACKGROUND/OBJECTIVES: Knowledge of @entity1566 ( @entity1566 ) bone changes has been derived primarily through cross-sectional studies, many of which are controvertible. Longitudinal studies are sparse, and long-term longitudinal chronic studies are unavailable. The objective of this study was to provide a clearer perception of @entity79 in @entity1 with complete @entity1566 . METHODS: Bone status of 31 individuals with chronic, complete @entity1566 was assessed twice using dual-energy xray absorptiometry at an average interval of 5.06 +/- 0.9 years. Because the sample of @entity1 was small (4), the primary analyses of change and comparisons of those with @entity451 vs @entity1688 were confined to the male @entity1 . RESULTS: Spine Z-scores showed a significant increase (P < 0.0001). The average Z-scores, initial and followup, were within the normal range. Hip Z-scores also showed a significant increase (P < 0.0001), and hip @entity79 ( @entity79 ) increased in 48% of the @entity1 . Knee @entity79 and lower extremity total bone mineral showed significant decreases (P < 0.003 and P < 0.02, respectively), but increases were seen in 33% and 26% at the respective sites. Individuals with @entity1688 had significantly lower values across all regions (P < 0.0001), and changes were significantly different compared with @entity451 (P < 0.0001). Bone values and changes in @entity1 vs @entity1 , despite the small sample of @entity1 , showed highly significant differences (P < 0.003-0.002). CONCLUSION: Chronic effects of complete @entity1566 do not exclusively result in continued loss of @entity79 or a static state of lowered @entity79 ; gain in @entity79 may occur. The nature and magnitude of the effects of complete @entity1566 on @entity79 vary by site, with sex and level of injury, which has implications for treatment and its assessment.
