Gastric lesions in portal @entity101 : inflammatory @entity3621 or XXXX ?

@entity1 @entity455 @entity101 @entity548 @entity384 @entity409 @entity3621
This paper reports the incidence and natural history of macroscopic @entity3621 in a series of 127 consecutive @entity1 with portal @entity101 of various aetiologies. @entity3621 was observed endoscopically in 65 @entity1 (51%) and was of two main types. Twenty eight @entity1 had severe or persistent @entity3621 which caused clinically significant @entity548 on 80 occasions and accounted for 25% of the bleeds from all sources. The remainder had mild @entity3621 . The presence of @entity3621 seemed to be independent of the severity of @entity409 or the degree of rise of wedged hepatic venous pressure and there was no difference in age, sex, or drugs prescribed in @entity1 with or without @entity3621 . The mean follow up period and the mean number of sclerotherapy treatments was significantly greater (p less than 0.005) in @entity1 with @entity3621 . Full thickness gastric biopsies in seven surgical @entity1 and 11 autopsy specimens showed @entity384 . Endoscopic biopsies in 14 @entity1 showed @entity455 in the mucosal layer which was in excess of the degree of inflammatory infiltrate. @entity3621 occurred in @entity1 with portal @entity101 of all common aetiologies and the clinical and pathological evidence supports the contention that it reflects a congested gastric mucosa and should be renamed @entity384 . As injection sclerotherapy improves survival from variceal @entity548 @entity384 may become more common. The response to conventional ('anti-erosive') therapy is poor and measures aimed at reducing the gastric portal pressure may be the only effective means of treating this condition.
