Heart rate variability during XXXX .

@entity1 @entity410 @entity302
RATIONALE: @entity410 may produce a variety of autonomic alterations. These alterations may occur due to evoked autonomic reflexes or as a direct cortical effect on autonomic control. In animal studies, lock step phenomena of interictal discharges to autonomic output have been repeatedly documented. However, the association of interictal discharges and autonomic output is not as well established in @entity1 . METHODS: RR intervals timely locked to @entity302 (RR(n)) were compared to RR intervals immediately following (RR(n+1)) interictal discharges in 40 @entity1 with focal onset @entity302 and low baseline heart beat variability. RESULTS: In 20 @entity1 with 200 left sided @entity302 , RR(n) shortened in 100 and prolonged in 31 when compared to RR(n+1) intervals. While in 20 @entity1 with 200 right sided @entity302 RR(n) intervals shortened in 17 and prolonged in 116 (Chi square P<0.001). No consistent differences in RR(n) intervals variability between frontal versus temporal localization of the interictal discharges from the same side was found. CONCLUSIONS: Interictal discharges, may influence autonomic control over the cardiac cycle and agree with animal studies. Further study of the relationship of interictal discharges to autonomic output is needed to delineate the potential lateralized influences over autonomic nervous system.
