Endoscopic ultrasound guided radiofrequency ablation, for XXXX .

@entity1 @entity788 @entity4929 @entity39 @entity5 @entity45 @entity490 @entity652
AIM: To outline the feasibility, safety, adverse events and early results of endoscopic ultrasound (EUS)-radiofrequency ablation (RFA) in @entity788 using a novel probe. METHODS: This is a multi-center, pilot safety feasibility study. The intervention described was radiofrequency ablation (RF) which was applied with an innovative monopolar RF probe (1.2 mm Habib EUS-RFA catheter) placed through a 19 or 22 gauge fine needle aspiration (FNA) needle once FNA was performed in @entity1 with a @entity5 in the head of the pancreas. The Habib    EUS-RFA is a 1 Fr wire (0.33 mm, 0.013") with a working length of 190 cm, which can be inserted through the biopsy channel of an echoendoscope. RF power is applied to the electrode at the end of the wire to coagulate tissue in the liver and pancreas. RESULTS: Eight @entity1 [median age of 65 (range 27-82) years; 7 female and 1 male] were recruited in a prospective multicenter trial. Six had a @entity788 (four a @entity45 , one had @entity4929 and one a @entity652 ) and two had a @entity5 ( @entity5 ) in the head of pancreas. The mean size of the @entity5 and @entity5 were 36.5 mm (SD    17.9 mm) and 27.5 mm (SD    17.7 mm) respectively. The EUS-RFA was successfully completed in all cases. Among the 6 @entity1 with a @entity5 , post procedure imaging in 3-6 mo showed complete resolution of the cysts in 2 cases, whilst in three more there was a 48.4% reduction [mean pre RF 38.8 mm (SD    21.7 mm) vs mean post RF 20 mm (SD    17.1 mm)] in size. In regards to the @entity5 @entity1 , there was a change in vascularity and central @entity39 after EUS-RFA. No major complications were observed within 48 h of the procedure. Two @entity1 had mild @entity490 that resolved within 3 d. CONCLUSION: EUS-RFA of @entity788 with a novel monopolar RF probe was well tolerated in all cases. Our preliminary data suggest that the procedure is straightforward and safe. The response ranged from complete resolution to a 50% reduction in size.
