Factors associated with inadequate XXXX screening with flexible sigmoidoscopy.

@entity1 @entity43 @entity14
BACKGROUND AND STUDY AIM: Inadequate @entity14 limited endoscopic resources. We examined @entity1 factors associated with inadequate flexible sigmoidoscopy (FSG) screening at baseline screening and repeat screening 3-5 years later in 10 geographically-dispersed screening centers participating in the ongoing Prostate, Lung, Colorectal, and @entity43 Screening Trial. METHODS: A total of 64,554 @entity1 (aged 55-74) completed baseline questionnaires and underwent FSG at baseline. Of these, 39,385 @entity1 returned for repeat screening. We used logistic regression models to assess factors that are associated with inadequate FSG (defined as a study in which the depth of insertion of FSG was <50 cm or visual inspection was limited to <90% of the mucosal surface but without detection of a polyp or mass). RESULTS: Of 7084 (11%) @entity1 with inadequate FSG at baseline, 6496 (91.7%) had <50 cm depth of insertion (75.3% due to @entity1 discomfort) and 500 (7.1%) @entity1 had adequate depth of insertion but suboptimal bowel preparation. Compared to 55-59 year age group, advancing age in 5-year increments (odds ratios (OR) from 1.08 to 1.51) and female sex (OR = 2.40; 95% confidence interval (CI): 2.27-2.54) were associated with inadequate FSG. Obesity (BMI > 30 kg/m(2)) was associated with reduced odds (OR = 0.67; 95% CI: 0.62-0.72). Inadequate FSG screening at baseline was associated with inadequate FSG at repeat screening (OR = 6.24; 95% CI: 5.78-6.75). CONCLUSIONS: Sedation should be considered for @entity1 with inadequate FSG or an alternative @entity14 screening method should be recommended.
