XXXX in the VATER animal model.

@entity632 @entity1 @entity8 @entity3551 @entity365 @entity1494 @entity3041 @entity1146 @entity35 @entity1621 @entity790
BACKGROUND PURPOSE: @entity8 are a prominent feature of the VATER association. Administration of @entity632 to timed-pregnant @entity35 resulted in a spectrum of anomalies similar to the @entity1 VATER association. The aim of this study is to describe the @entity8 in the @entity632 animal model. METHODS: Timed-pregnant @entity35 were injected with @entity632 intraperitoneally at a dose of 2 mg/kg on days 6 through 9 of gestation. Full-term fetuses were fixed in Bouin's solution and serial transverse sections were analyzed by light microscopy. All specimens were compared with suitable controls. RESULTS: In experimental animals, @entity8 were found in 98% of the examined fetuses. @entity1621 with kinking of the ureters was obvious. Ureteric @entity1146 led to obstructive @entity3551 . @entity1494 occurred in all experimental animals. Mesonephric ducts were seen joining a proximally blind-ending urethra in male animals. In females both paramesonephric ducts ended blindly after joining each other, and this resulted in @entity365 . In association with imperforate anus, a recto-urethral and a @entity790 was seen in male and female fetuses, respectively. CONCLUSIONS: @entity1494 was an important feature in the @entity632 animal model. @entity3041 resulted from blind-ending ureters.
