New insights into the anti- XXXX activity of xanthones from Garcinia mangostana.

@entity32 @entity66 @entity28 @entity6 @entity209 @entity65
UNASSIGNED: Obesity has reached epidemic proportions worldwide. This condition, and its related diseases such as @entity6 and @entity65 , have become major public health challenges. Fruits are important dietary components, and bioactive constituents from fruits are considered to be a promising source for developing effective and safe anti- @entity28 drugs. Garcinia mangostana Linn. (Clusiaceae) is a tropical evergreen tree, and its fruit, mangosteen, is called 'Queen of Fruit'. The pericarp of G. mangostana has been used for centuries in Southeast Asia as a medicinal agent for treatment of @entity66 . Products derived from mangosteen are widely consumed to ameliorate @entity209 and resultant @entity209 . However, the chemical principles and mechanisms underlying these effects are unclear. This review summarizes the recent chemical and pharmacological studies related to G. mangostana, including weight reduction, anti-adipogenesis, anti- @entity32 and anti-oxidation activity. The aim of this review is to shed light on the role of G. mangostana and its constituents in preventing and treating @entity28 , which should encourage more interest in the development of relevant therapeutic methods.
