Corynebacterium spp as causative agents of microbial XXXX .

@entity1 @entity7046 @entity2176 @entity7048 @entity1036 @entity2177 @entity281 @entity2755 @entity800
PURPOSE: To report the clinical and microbiological profile of @entity1036 caused by Corynebacterium spp. METHODS: The medical and microbiology records of 22 @entity1 , who had presented at the L V Prasad Eye Institute, Bhubaneswar, between June 2009 and December 2012, and whose corneal scrapings had yielded significant growth of Corynebacterium spp, were retrospectively reviewed. A detailed ocular examination was performed before the respective corneal scraping was sent for a microbiological work-up. The data collected from each record included age, gender, predisposing factors (ocular and systemic), clinical presentation, management and outcome of treatment. RESULTS: The mean age of the @entity1 was 43.8  24.4   years. Ocular predisposing factor was present in 14 (63.6%) eyes. Surgical intervention was required in 12 (54.5%) @entity1 . In vitro susceptibility (Kirby-Bauer disc diffusion method) results of Corynebacterium spp to @entity2176 (17/19, 89.5%), @entity7048 (16/20, 80%), @entity2755 (11/20, 55%), @entity800 (13/19, 68.4%), @entity2177 (10/20, 50%) and @entity7046 (10/19, 52.6%) were variable. Drug resistance (more than one drug) was seen in nine (40.9%) Corynebacterium isolates, of which, two (22.2%) showed multidrug resistance to three or more classes of antibiotics. CONCLUSIONS: Corynebacteria can cause severe @entity281 requiring surgical intervention.
