Relation of various degrees of body mass index in XXXX with systemic @entity101 to left ventricular mass, cardiac output, and peripheral resistance (The @entity101 Genetic Epidemiology Network Study).

@entity1 @entity64 @entity101 @entity28 @entity998 @entity1386 @entity2973 @entity4346 @entity65
The impact of different methods of indexation of left ventricular (LV) mass and systemic hemodynamic variables on prevalences and correlates of @entity65 in relation to level of @entity28 in populations remains unclear. We evaluated 1,672 @entity1 in the @entity101 Genetic Epidemiology Network Study to investigate the relations of @entity2973 and level of @entity28 to LV mass and prevalences of @entity4346 , @entity998 , and peripheral resistance detected using different indexations for body size. In our study population, 1,577 subjects were clinically healthy nondiabetic @entity101 and 95 were normotensive normal-weight nondiabetic reference subjects. @entity1386 ( @entity1386 ) did not differ between the reference group and the normal-weight @entity101 subjects, and increased with @entity2973 . In @entity101 subjects, LV mass and cardiac output increased and total peripheral resistance decreased with @entity2973 . Indexation of LV mass for @entity1386 or body surface area (BSA) resulted in no difference or even lower prevalence of @entity4346 in severely @entity28 compared with normal-weight @entity101 subjects. In contrast, indexation of LV mass for height(2.7) identified an increased prevalence of @entity4346 with @entity2973 and @entity28 . Absolute cardiac output increased and total peripheral resistance decreased with @entity2973 . Prevalence of elevated cardiac output indexed for height(1.83) increased and for elevated total peripheral resistance-height(1.83) index decreased with greater @entity2973 , whereas opposite trends were seen when cardiac output and total peripheral resistance were indexed for BSA or @entity1386 . Thus, in @entity101 subjects, @entity1386 increases with @entity2973 and is directly related to LV mass, @entity64 volume, and cardiac output, and inversely related to total peripheral resistance. Indexations of LV mass and systemic hemodynamics for @entity1386 or BSA obscured associations of @entity4346 and abnormal cardiac and total peripheral resistance indexes with @entity2973 , whereas LV mass/height(2,7), cardiac output/height(1.83), and total peripheral resistance-height(1.83) detected significant preclinical @entity65 with @entity28 .
