[The significance of HLA @entity25783 and DR8 among XXXX with @entity309 ].

@entity1 @entity71190 @entity25783 @entity309 @entity4107
Among 380 @entity1 with @entity309 ( @entity309 ), there were 63 cases who had HLA @entity4107 without any other counterpart DR type (Group @entity4107 .*), 30 with @entity25783 but without @entity4107 (Group @entity71190 ), 37 with both @entity25783 and @entity4107 (Group @entity71190 ), 34 with DR8 but without @entity4107 (Group @entity4107 ), and 15 with both DR8 and @entity4107 (Group @entity4107 ). 53, 29, 32, 32, or 13 female @entity309 @entity1 respectively from Groups @entity4107 .*, @entity71190 , @entity71190 +, @entity4107 -, or @entity4107 + were investigated for the severity of their disease. 40 joints in 18 @entity1 , 2 in 1, 19 in 8, 13 in 6, or 10 in 4 respectively from Groups @entity4107 .*, @entity71190 , @entity71190 +, @entity4107 -, or @entity4107 had had the previous history of total joint replacement operations for the diseased hips (THR) or knees (TKR). The number of cases (p < 0.01) or that of joints (p < 0.001) was significantly less among Group @entity71190 - @entity1 than the corresponding figure among Group @entity4107 .* @entity1 . Significantly smaller (p < 0.02) number of cases with @entity25783 (Groups @entity71190 combined) had experienced THR's and/or TKR's than those in Group @entity4107 .*. Group @entity4107 - @entity1 had undergone THR/TKR operations in smaller number of the joints (p < 0.05) in comparison to Group @entity4107 .* @entity1 , though the difference was not significant when the numbers of operated cases were compared between the Groups. The age at @entity309 onset among Groups @entity4107 .*, @entity71190 , @entity71190 +, @entity4107 -, or @entity4107 + was 38.5 +/- 14.2 (mean +/- SD) years, 46.6 +/- 12.2, 41.7 +/- 11.7, 44.9 +/- 13.1, or 40.8 +/- 10.2 respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
