Correlation of local blood flow, @entity413 consumption and probability of XXXX following a @entity2500 in the cat.

@entity66 @entity39 @entity2500 @entity1188 @entity4320 @entity468 @entity413
At defined coronal sections, the surface area of infarcted tissue was measured 4 days after the occlusion of the middle artery in 11 @entity468 . In groups of @entity468 treated with @entity4320 (5.6 and 16.7 microgram/kg . min over 3 h. 5 min after the occlusion), the infarcted surface was significantly decreased. The topographic localization of the @entity1188 was studied in control and treated @entity468 . This established @entity39 was correlated with measures of focal cerebral blood flow and @entity413 consumption 3.5 h after the @entity2500 . Grey matter blood flow was universally low in untreated @entity468 , but in @entity468 treated with @entity4320 (5.6 microgram/kg . min) cortical and caudate nucleus blood flow was 2-3 times greater, even in those regions that were later infarcted in the treated @entity468 . @entity413 consumption was similarly reduced in untreated @entity468 but there was little difference between the control and drug-treated @entity468 except in some areas where drug treatment appeared to further reduce the values for focal @entity413 consumption. These regions correlated with those in which @entity1188 was later found in the @entity468 treated with @entity4320 . It is hoped that such correlations between pathology. flow and metabolism could help the search for effective pharmacotherapy of @entity66 .
