The effect of XXXX on reported @entity565 symptoms.

@entity1 @entity565 @entity3617 @entity1729
BACKGROUND: Wheezing and chest tightness is associated with @entity1729 . Thus the occurrence of @entity1729 may influence the prevalence of @entity565 . AIMS: To assess the strength of relation between two main symptoms of @entity565 and the prevalence of @entity1729 in @entity1 with and without @entity565 . METHODS: The study population was 3,796 @entity1 , four years of age, whose parents had answered a questionnaire on respiratory symptoms and @entity565 . The prevalence of wheezing and chest tightness in the last 12 months and four weeks was estimated according to the occurrence of @entity1729 during the corresponding time periods; 95% confidence intervals of the prevalence and the statistical significance of the differences in the prevalence by using chi-square test were calculated. RESULTS: The prevalence of wheezing and chest tightness was higher in @entity1 who had experienced @entity1729 than in those who had not. The prevalence of wheezing was 17.5% among @entity1 who had experienced @entity3617 and 3.0% among @entity1 whom had not (p<0.001). The prevalence of chest tightness in the last 12 months was 3.7% (95% CI 3.1-4.1) among @entity1 without @entity565 and 59.3% (95% CI 53.4-65.2) among @entity1 with @entity565 (p<0.001). The prevalence of wheezing and chest tightness increased with increasing number of different types of @entity1729 among @entity1 without @entity565 (p<0.001) and tended to be so among @entity1 with @entity565 . CONCLUSIONS: These findings have implications for the interpretation of results from epidemiological studies using respiratory symptoms as a health-related outcome of @entity565 .
