Long-term outcomes after treatment for T1 XXXX .

@entity1 @entity3012 @entity3 @entity14 @entity694
PURPOSE: Long-term outcomes of @entity1 with T1 @entity14 ( @entity14 ) treated by endoscopic resection (ER) or surgical resection are unclear in relation to the curative criteria in the Japanese Society for @entity694 (JSCCR) guidelines. The aim of this study was to retrospectively compare the long-term outcomes among @entity1 with T1 @entity14 in relation to the treatment methods. METHODS: We examined 322 T1 @entity14 cases treated between January 1992 and August 2008 at Hiroshima University Hospital. @entity1 who did not meet the curative criteria in the JSCCR guidelines were defined as "non-endoscopically curable" and classified into three groups: underwent ER alone (group A: 45 @entity1 ), underwent additional surgery after ER (group B: 106 @entity1 ), and underwent surgical resection alone (group C: 92 @entity1 ). RESULTS: Of the 322 T1 @entity14 @entity1 , 79 were categorized as endoscopically curable and 243 as non-endoscopically curable. Among the endoscopically curable T1 @entity14 @entity1 , recurrence and 5-year @entity3012 rates were 0 and 94.2  %, respectively. In groups A, B, and C, recurrence rates were 4.4, 6.6, and 4.3  %, and @entity3012 rates were 85.6, 95.1, and 96.3  %, respectively (p   <   0.05). Local recurrence or distant/lymph node @entity3 was observed in 13 @entity1 (group A: 2; group B: 7; group C: 4). Death due to primary @entity14 occurred in six @entity1 (group B: 4; group C: 2). CONCLUSION: Long-term outcomes support the curative criteria according to the JSCCR guidelines. ER for T1 @entity14 did not worsen clinical outcomes in cases that required additional surgical resection.
