Diagnostic performance of (18)F-fluorodeoxyglucose PET/CT and bone scintigraphy in XXXX @entity1 with suspected bone @entity3 .

@entity1 @entity0 @entity5 @entity158 @entity3 @entity10673
BACKGROUND: We prospectively compared the diagnostic accuracies of PET/CT and @entity10673 in @entity1 with suspected bone @entity3 from @entity0 . METHODS: This single-institution prospective study included consecutive @entity1 with suspected bone @entity3 from biopsy-proven @entity0 seen at Tokai University Hospital between September 2011 and March 2014. Inclusion criteria included suspicions for bone @entity3 (bone @entity158 , elevated alkaline phosphatase, elevated @entity5 markers, or suspected bone @entity3 by @entity10673 ). Two nuclear medicine physicians evaluated PET/CT and @entity10673 images. RESULTS: Thirty @entity1 were initially enrolled in this study. Two were excluded from the analyses because they declined to undergo imaging during follow-up. PET/CT successfully detected bone @entity3 in all 10 @entity1 finally diagnosed with the condition, whereas @entity10673 identified 2. The two methods were not highly concordant in detecting osseous @entity3 . In 19 of 28 paired studies (68  %), 2 (10  %) were positive for @entity3 , and 17 (90  %) were negative. Nine occurrences (32  %) were discordant; of these, 2 were PET/CT positive and @entity10673 negative; 5 were PET/CT positive and @entity10673 equivocal; one was PET/CT negative and @entity10673 equivocal, and one was PET/CT equivocal and @entity10673 negative. CONCLUSIONS: Our results indicated that PET/CT was superior to @entity10673 for the diagnosis of bone @entity3 . On the basis of the results of previous studies as well as ours, PET/CT could replace @entity10673 as the initial modality to detect bone @entity3 in @entity1 suspected for the condition.
