Antifeeding effect of several insecticidal formulations against Ctenocephalides felis on XXXX .

@entity2960 @entity276 @entity28962 @entity11101 @entity277 @entity315 @entity468 @entity204 @entity5051
Evaluation of insecticidal activity of flea products is generally based on counting live @entity11101 in the animal's coat 24 and 48 hours following artificial @entity277 . This approach, however, does not allow to specify whether the @entity11101 have had the opportunity to bite and take a bloodmeal prior to their @entity204 . To address this question, 30 @entity468 were alloted to six groups of five animals. Each cat was housed in a separate cage. At Day 0, each group of @entity468 received a single treatment as follows: Group 1: spot-on application of @entity5051 : @entity468 < 4 kg: 40 mg/cat, @entity468 > or = 4 kg: 80 mg/cat (Advantage). Group 2: spot-on application of @entity276 : 50 mg/cat (Frontline spot-on). Group 3: spray application of @entity276 : 7.5 mg/kg b.w. (Frontline spray). Group 4: foam application of @entity315 40/60: 50 mg/kg b.w. (Defencat). Group 5: aerosol spray application of @entity28962 + @entity2960 : one second/kg b.w. (NuvanTop). Group 6: control group: @entity468 were left untreated. One hour after treatment, each cat was infested with 50 unengorged young adult @entity11101 , Ctenocephalides felis, deposited along the dorsal midline. One hour later, each cat was carefully combed using a fine-toothed comb (13 teeth/cm). Collected @entity11101 were swatted to deteci blood in their abdomen. To the manufacturers respective product use instructions and efficacy claims, reeinfestations were made at Days 3, 7, 14 in all groups; at Days 21 and 30 in Groups 1, 2, 4, 6; at Days 35 and 42 in Groups 3 and 6. The @entity468 were combed one hour after each reinfestation. The results indicate that the topical application of @entity5051 or @entity276 does not prevent @entity11101 from biting and feeding within the first hour after @entity277 prior to being killed while the topical application of @entity28962 / @entity2960 and @entity315 let to a better than 80% decrease of the number of engorged @entity11101 for three and seven days post treatment, respectively.
