Prevalence and prognostic value of right XXXX in severe @entity472 .

@entity1 @entity67 @entity409 @entity472 @entity299 @entity340 @entity65 @entity1002
AIMS: Systolic pulmonary artery pressure (sPAP) is a well-known outcome predictor in @entity1 with @entity340 . Limited data are available regarding the evaluation of right ventricular (RV) performance, particularly in @entity1 with @entity472 ( @entity472 ). The aim of this study was to evaluate the prevalence, determinants, and prognostic significance of @entity67 in severe @entity472 independently from the strategy of treatment chosen. METHODS AND RESULTS: Two hundred @entity1 (mean age: 79.9    8.8 years) with severe @entity472 underwent two-dimensional and speckle tracking echocardiography for the evaluation of left ventricular (LV) and RV functions, aortic valve gradients, and sPAP. A @entity299 ( @entity299 )  <=17 mm defined @entity67 . @entity67 was detected in 48 @entity1 (24%). At multivariable regression analysis, @entity1002 (r = -0.29, P = 0.001), mean aortic gradient (r = 0.25, P = 0.002), and LV ejection fraction (r = 0.18, P = 0.02) were well correlated with @entity299 . After a median 16-month follow-up, @entity65 occurred in 17 @entity1 . At multivariate Cox regression analysis, @entity409 ( @entity299  <=17 mm and LVEF  <=50%) emerged as the strongest predictor of prognosis (hazard ratio 4.08, 95% confidence interval 1.36-12.22; P = 0.012). CONCLUSIONS: @entity67 is common in @entity472 @entity1 , and this finding can likely be accounted for by the RV-LV interdependence. Given that biventricular function impairment was a strong predictor of mortality in our population, we suggest that @entity67 should be systematically looked for in @entity472 @entity1 .
