Predictive factors for complete response of chemoembolization with drug-eluting beads (DEB-TACE) for XXXX .

@entity1 @entity157 @entity82 @entity5
OBJECTIVES: To identify clinical and imaging features associated with complete response (CR) to first session of transarterial chemoembolization (TACE) with drug-eluting beads (DEB) in @entity1 with @entity157 . METHODS: In this prospective historical cohort, 172 @entity1 with 315 @entity5 who received at least one DEB-TACE from 2007 to 2013 were studied. Imaging response was evaluated according to the modified Response Evaluation Criteria in Solid Tumours (mRECIST). Age, gender, aetiology of @entity82 , @entity1 and BCLC scores, particles size, location in the liver, size of the @entity5 , presence of a capsule, hypervascularisation on DSA and CT/MRI scans, and blush extinction were analysed. RESULTS: After one session of treatment, CR was observed in 36  % of the 315 @entity5 treated. Nodule size, location in the liver, and complete blush extinction on DSA was statistically correlated to complete response, whereas capsule aspect on imaging and demographic criteria were not. In multivariate analysis only, location in the liver and nodule size were significant features. CONCLUSIONS: @entity5 location in the segments 1 and 4 is a pejorative factor for CR, whereas @entity5 size <5  cm is a positive predictive factor. These criteria could, therefore, be taken into consideration to improve the selection of @entity1 for DEB-TACE. KEY POINTS:     Literature on predictive factors of complete response after DEB-TACE is under-studied.     @entity5 size <5  cm is associated with complete response.     Location in segments 1 or 4 is a pejorative factor for response.     No demographic parameter influences complete response.
