[Effects of active and passive smoking during pregnancy on the development of gestational XXXX and fetal hypotrophy].

@entity1 @entity286 @entity101 @entity8403 @entity1239 @entity4874
In prenatal life the fetus can be exposed to more incentires which affect the mother. In case of both active and passive smoking by pregnant @entity1 many pernicious substances contained in @entity286 smoke can influence the foetus. The components of @entity286 smoke can contribute to various antenatal complications. The aim of present work was to assess if the data given by the @entity1 in anonymous questionnaire go along with the real exposure to components of smoke assessed on the basis of concentration of @entity1239 metabolite- @entity4874 in mother's serum and next to assess the risk of development of gestational @entity101 and hypotrophy. The biological material was extracted with means of liquid-liquid technique and next we performed laboratory determinations with means of liquid chro- matography with sectrophotometric detection, in which @entity8403 is used as inner sample. The study was carried out on 106 @entity1 in perinatal period who give birth from single, full term pregnancy. On the basis of questionnaire data considering the concentration of @entity4874 , the @entity1 were divided into three groups: I group--active smokers (n = 27), II group--passive smokers (n = 32), III group--not exposed to @entity286 smoke (n = 41). The average concentration of @entity4874 in blood serum in the first group was 129.6 ng/ml, second group--5.1 ng/ ml, but in all @entity1 from the control group the concentration of @entity4874 was below the detection level. Gestational @entity101 was diagnosed in 17 @entity1 (16%) and hypotrophy of the foetus was diagnosed in 15 @entity1 (14%). @entity286 smoking didn't influence the development of gestational @entity101 and hypotrophy showered it is more often observed in @entity1 exposed to components of @entity286 smoke during pregnancy.
