Mild @entity75 with reversible XXXX : An important differential of encephalitis.

@entity1 @entity2803 @entity410 @entity573 @entity146 @entity75 @entity16 @entity1833 @entity911 @entity7822 @entity5746 @entity2753 @entity2055 @entity1851
UNASSIGNED: Mild @entity75 with a reversible @entity75 ( @entity7822 ) is a clinico-radiological syndrome characterized by a transient mild @entity75 and a reversible lesion in the splenium of the corpus callosum on MRI. This syndrome has almost universally been described in @entity1 from Japan and East Asia. Here we describe seven cases of @entity7822 occurring in Caucasian Australian @entity1 from one centre seen over a 3 year period. All @entity1 had a fever-associated @entity75 (n  =  7), which presented with @entity911 (n  =  4), @entity146 (n  =  3), lethargy (n  =  3), slurred speech (n  =  3), drowsiness (n  =  2) and @entity1833 (n  =  2). Other @entity16 included @entity2055 (n  =  5) and @entity410 (n  =  1). These symptoms resolved rapidly over 4-6 days followed by complete neurological recovery. In all @entity1 , MRI performed within 1-3 days of onset of @entity75 demonstrated a symmetrical diffusion-restricted lesion in the splenium of the corpus callosum. Three @entity1 had additional lesions involving other parts of the corpus callosum and adjacent periventricular white matter. These same three @entity1 had mild persisting white matter changes evident at followup MRI, while the other @entity1 had complete resolution of radiological changes. A potential trigger was present in five of the seven cases: @entity573 , @entity5746 , @entity2803 , influenza B and adenovirus (all n  =  1). Elevated white cell count (n  =  4), elevated @entity1851 (n  =  5) and @entity2753 (n  =  6) were commonly observed. CSF was performed in four @entity1 , which showed no pleocytosis. This case series of @entity7822 demonstrates this condition occurs outside of East Asia and is an important differential to consider in @entity1 presenting with acute @entity75 .
