Relationships between physical activity, XXXX levels and lipids in non-diabetic low income residents of Mexico City: the Mexico City Diabetes Study.

@entity1 @entity172 @entity2690 @entity412 @entity413 @entity165
The epidemiologic data supporting an association between physical activity and lipoprotein profile is controversial. We hypothesized that physical activity is positively associated with @entity412 levels and negatively associated with high density lipoprotein (HDL) @entity165 levels, and that these associations are mediated by @entity2690 activity. We tested these hypotheses in 819 male and 1159 female healthy non-diabetic Mexicans, aged 35-64 years, residing in Mexico City. Physical activity was assessed using a modified Stanford 7-day Physical Activity Recall. Serum @entity413 and @entity2690 were evaluated in the fasting state and 2 h following a @entity413 challenge. Crude analysis indicated that physical activity was not associated with HDL @entity165 in males, but was associated with HDL @entity165 in females (r = 0.06; p = 0.025). Physical activity was not associated with @entity412 concentration in males or females. Multivariate results showed that the positive association between HDL @entity165 and physical activity in @entity1 remained after controlling for age, @entity172 status, body mass index, and smoking. Furthermore, there was a significant interaction between physical activity, HDL @entity165 and an index of @entity2690 sensitivity. @entity1 with higher levels of @entity2690 sensitivity had higher levels of HDL @entity165 . However, among @entity1 at lower levels of @entity2690 sensitivity, those with greater physical activity were significantly more likely to have higher HDL @entity165 values.
