[Impact of XXXX on health-related quality of life].

@entity1 @entity1569 @entity458 @entity111 @entity717
BACKGROUND AND OBJECTIVE: Different studies have reported of physical, social and @entity458 in @entity1 with @entity1569 . Nevertheless, its impact on the health-related quality of life is not clarified sufficiently. Our objective is to know the repercussion of the moderate-severe @entity1569 on the health-related quality of life with the Psoriasis Disability Index (PDI). @entity1 AND METHOD: An observational, cross-sectional, international study developed in dermatology practices in Spain and Portugal. During a period of 9 months, 332 participating dermatologist included a minimum of 10 consecutive @entity1 with moderate to severe @entity1569 . The date report form includes information about the health-related quality of life (PDI), as well as objective variables of severity as body surface area and PASI (Psoriasis Area and Severity Index), @entity111 , costs and willingness to pay. RESULTS: A total of 3,320 @entity1 were assessed. The majority of cases were males (57%) and the mean age at study inclusion time was 47 years. The mean value of the PDI was 8.93 (95% confidence interval, 7.83-9.21), which represents a percentage of @entity717 lower than 20%. The floor effect varies between 8.3% and 61.2%, and the ceiling effect varies between 0% and 3%. The correlations between the PDI and objective variables of severity (PASI and body surface area) were weak though statistically significant (p < 0.001) They all indicate that to higher severity of the @entity1569 , upper negative impact in the health-related quality of life. CONCLUSIONS: Psoriasis causes a negative impact in the health-related quality of life, though the magnitudes are weak and suggest some problems with the questionnaire. Possibly, the PDI reflects more the disability that the form in which the @entity1 perceive and react to their state of health, and, several items seem to have a scanty applicability in the Spanish and Portuguese population. The PDI doesn't seem the appropriate instrument for this type of @entity1 in our environment.
