Is the @entity49 state in @entity955 mediated by XXXX ?

@entity1 @entity64 @entity7 @entity5 @entity731 @entity49 @entity3459 @entity1031 @entity955 @entity453 @entity943
BACKGROUND AND PURPOSE: Tissue factor (TF; an @entity3459 ) and @entity7 ( @entity7 ; a marker of angiogenesis) are involved in the @entity49 state associated with @entity5 . We investigated their roles in chronic @entity955 ( @entity955 ), a condition also associated with increased risk of @entity64 and @entity1031 , as well as a prothrombotic or @entity49 state. METHODS: We studied 25 @entity1 with @entity955 (20 @entity1 ; mean+/-SD age, 62+/-13 years) who were compared with 2 control groups in sinus rhythm: 30 healthy control subjects (17 @entity1 ; mean age, 60+/-9 years) and 35 @entity1 control subjects with @entity453 ( @entity453 ; 27 @entity1 ; mean age, 60+/-12 years). Plasma levels of TF, @entity7 , and the @entity7 receptor sFlt-1 were measured by enzyme-linked immunosorbent assay. RESULTS: @entity7 , sFlt-1, and TF were significantly different between the 3 groups, with abnormal levels in @entity955 and @entity453 @entity1 compared with control subjects (P<0.001, P=0.022, and P=0.008, respectively). Among the @entity955 @entity1 , TF levels were significantly correlated with @entity7 (Spearman's r=0.65, P<0.001) and sFlt (r=0.54, P=0.006) levels. Only TF and @entity7 levels were significantly correlated in @entity453 @entity1 (r=0.39, P=0.02). There were no significant correlations among the healthy control subjects. CONCLUSIONS: @entity1 with chronic @entity955 have high TF levels, in keeping with the prothrombotic state associated with this @entity943 . The relationships between TF and @entity7 and its receptor sFlt-1 in @entity955 suggest a possible role for @entity7 in the @entity49 state found in @entity955 , as seen in @entity5 and @entity731 .
