Levels of immunoglobulin G, M, A, and E at various ages in XXXX and white individuals.

@entity1 @entity2023 @entity565 @entity566 @entity56
Studies were conducted to detect major differences in immunoglobulin levels between @entity56 and nonallergic individuals. Immunoglobulins G, M, A, and E were quantitated in members of 63 families selected for the presence of @entity1 with @entity565 or @entity2023 and compared with a larger group of healthy individuals and families. Mean IgE levels were significantly higher in healthy black than in white individuals. No significant difference was found in IgE levels between healthy parents with and without @entity56 @entity1 . Mean IgE levels were significantly higher in asthmatic @entity1 than in healthy @entity1 and also much higher in asthmatic @entity1 than in their healthy siblings. @entity565 occurred more frequently in @entity1 than in @entity1 . IgE levels in healthy @entity1 increased rapidly early in childhood, reached a peak before 10 yr of age, and decreased during the teens. This decrease in IgE during the teens may provide the immunologic mechanism by which some @entity1 can "outgrow" certain childhood @entity566 . IgA levels were very low in young @entity1 and not significantly different between @entity56 and healthy individuals. The low IgA level in young @entity1 may be of importance in the development of childhood @entity566 .
