Doppler ultrasound for diagnosis of soft tissue XXXX : efficacy of ultrasound-based screening score.

@entity5 @entity1 @entity242
BACKGROUND: The utility of ultrasound imaging in the screening of soft-part @entity5 (SPTs) has been reported. We classified SPTs according to their blood flow pattern on Doppler ultrasound and re-evaluated the efficacy of this imaging modality as a screening method. Additionally, we combined Doppler ultrasound with several values to improve the diagnostic efficacy and to establish a new diagnostic tool. @entity1 AND METHODS: This study included 189 cases of pathologically confirmed SPTs (122 cases of benign disease including @entity5 and 67 cases of malignant SPTs). Ultrasound imaging included evaluation of vascularity by colour Doppler. We established a scoring system to more effectively differentiate malignant from benign SPTs (ultrasound-based @entity242 screening [USS] score). RESULTS: The mean scores in the benign and malignant groups were 1.47    0.93 and 3.42    1.30, respectively. @entity1 with malignant masses showed significantly higher USS scores than did those with benign masses (p < 1 * 10(-10)). The area under the curve was 0.88 by receiver operating characteristic (ROC) analysis. Based on the cut-off value (3 points) calculated by ROC curve analysis, the sensitivity and specificity for a diagnosis of malignant SPT was 85.1% and 86.9%, respectively. CONCLUSIONS: Assessment of vascularity by Doppler ultrasound alone is insufficient for differentiation between benign and malignant SPTs. Preoperative diagnosis of most SPTs is possible by combining our USS score with characteristic clinical and magnetic resonance imaging findings.
