Efficacy and tolerance of acne treatment using both XXXX and a combined contraceptive containing @entity4863 .

@entity1 @entity38407 @entity5477 @entity2082 @entity4863 @entity972 @entity1482
BACKGROUND: The use of either oral contraceptives or antiandrogens has been shown to be helpful in the treatment of @entity1 with acne. OBJECTIVES: We investigated the safety and efficacy of acne treatment using both @entity1482 and a combined contraceptive containing @entity4863 . METHODS: Twenty-seven @entity1 with either severe papular or nodulocystic facial acne were treated with a combined oral contraceptive containing 30 mug @entity2082 and 3 mg @entity4863 (EE/ @entity38407 ; Yasmin) and @entity1482 (SL) 100 mg taken daily. A serum @entity972 level was obtained before initiation of therapy. Between 4 and 6 weeks after the start of both medications, a second serum @entity972 level was obtained. Side effects were recorded. RESULTS: No significant elevation of serum @entity972 was found in any of the subjects nor were there any reported additional side effects significant enough to discontinue treatment. At follow up, 85% of subjects were entirely clear of acne lesions or had excellent improvement, 7.4% were mildly improved, and 7.4% were not improved. LIMITATIONS: This was a small prospective study. CONCLUSION: The combination of EE/ @entity38407 mg daily appears to have efficacy and is well tolerated in the treatment of severe papular and @entity5477 in @entity1 .
