[Clinical analysis of diagnosis and treatment for retroperitoneal malignant XXXX ].

@entity1 @entity82 @entity5 @entity1418
OBJECTIVE: To explore the clinical characteristics of retroperitoneal malignant @entity82 ( @entity1418 ) and to retrospectively evaluate the outcome of treatment and identify prognostic factors for survival time. METHODS: The records of 38 @entity1 with retroperitoneal malignant @entity82 ( @entity1418 ) managed with surgery from March 2000 to August 2013 were retrospectively reviewed. RESULTS: All @entity1 received surgical resection, including 23 @entity5 and 15 recurrent @entity5 . 20 @entity1 received radical resection, 18 cases received palliative resection. The 19 @entity1 (95%) received complete resection got @entity5 recurrence. The overall 1-, 3-, 5-year survival rate were 62.9%, 35.2% and 4.4% and the median survival time was 15.5 (1-157) months. Log-rank test indicated that @entity5 grade ((  (2) = 10.667, P < 0.01) and radical surgery (  (2) = 18.476, P < 0.01) were associated with postoperative survival time. The difference between gender ((  (2) = 3.329, P = 0.068), age ((  (2) = 0.426, P = 0.514), removal of the joint organs ((  (2) = 3.725, P = 0.054), blood transfusion ((  (2) = 0.044, P = 0.833), @entity5 size ((  (2) = 1.647, P = 0.199), @entity5 metastasis ((  (2) = 0.345, P = 0.557), adjuvant therapy ((  (2) = 1.992, P = 0.158), recurrent disease ((  (2) = 0.163, P = 0.640) got no statistical significance. Multivariate analysis indicated that radical surgery and @entity5 grade were prognostic indicators for retroperitoneal malignant @entity82 (RR = 4.888, P = 0.001; HR = 4.436, P = 0.006). CONCLUSIONS: @entity1418 ( @entity1418 ) has high malignant degree and is difficult to treat. The prognosis is poor. Complete resection remains the main method for retroperitoneal malignant @entity82 . It often requires the resection of other adjacent organs in order to reach the goal of radical resection. Incomplete resection and high grade (grade 3) predict shorter postoperative survival time.
