Quantification of liver, pancreas, kidney, and vertebral body MRI-PDFF in XXXX .

@entity1 @entity8 @entity788 @entity6 @entity174 @entity1561
PURPOSE: The purpose of the present study was to determine liver, pancreas, kidney, and vertebral fat deposition in @entity1561 @entity1 by proton density fat fraction (PDFF) using magnetic resonance imaging (MRI) and to evaluate the relationships among them. METHODS: A total of 41 biopsy-proven @entity1561 @entity1 underwent MRI-PDFF with IDEAL-IQ. MRI protocol included T1-independent volumetric multi-echo gradient-echo imaging with T2* correction and spectral fat modeling. The MR examinations were performed on a 1.5 HDx MRI system. MRI-PDFF measurements were obtained from liver, @entity8 . Liver biopsy specimens were retrieved from the archives and evaluated by one pathologist according to NASH CRN. RESULTS: The median age of the @entity1 was 47  years. The median interval between liver biopsy and MRI examination was 16  days. Mean liver, @entity8 , T12 and L1 vertebral body MRI-PDFFs were 18.7%, 5.7%, 1.7%, 51%, 43.2%, and 43.5%, respectively. No correlation between either liver MRI-PDFF or histological steatosis, and other organ MRI-PDFFs was observed. A good correlation between @entity788 was observed. @entity6 @entity1 had higher average pancreas MRI-PDFF compared to non- @entity6 (12.2%, vs., 4.8%; P  =  0.028). CONCLUSIONS: Pancreas and vertebral body MRI-PDFF is well correlated in @entity1561 @entity1 and both of them are higher in @entity6 @entity1 which may explain @entity174 in @entity6 . MRI-PDFF can be used to demonstrate fat fractions of different organs and tissues and to understand fat metabolism.
