The effect of sacral nerve modulation on cerebral evoked potential latency in fecal @entity322 and XXXX .

@entity1 @entity1142 @entity322 @entity4666
OBJECTIVE: Influence of sacral nerve modulation (SNM) on cerebral somatosensory evoked potentials (SEP) was determined in @entity1 with @entity322 and @entity1142 . BACKGROUND: Selection of @entity1 with @entity322 and @entity1142 for SNM could be improved. METHODS: The latency (ms) of SEP induced by pudendal nerve stimulation was compared before (T0) and at 1 month during peripheral nerve evaluation (PNE) of SNM at frequencies of 21 Hz (T1) and 40 Hz (T2). The results were correlated with clinical outcome at 6 months. RESULTS: In 16 of 23 incontinent @entity1 with clinical "success" from SNM (Wexner @entity322 score  <=7), there was a significant difference between @entity4666 latency at T0 and T2 (38.81 vs. 37.49 ms, P = 0.049). In the 7 with "failure," there was no change between T0 and T2. In 12 of 19 @entity1142 @entity1 with "success" (Wexner @entity1142 score  <=15), there was no difference between T0 and T2 @entity4666 latency (39.28 vs. 38.25 ms, P = 0.374). In the 7 with "failure," there was a significant fall in @entity4666 latency (41.20 vs. 39.30 ms, P = 0.047) but not to the normal range. The T0 @entity4666 latency in incontinent @entity1 having "success" was significantly higher than in the normal range (P = 0.044). In @entity1142 @entity1 it was significantly higher than in the normal range in both those with "success" (P = 0.001) and "failure" (P = 0.022). CONCLUSIONS: Measurement of @entity4666 latency of SEP at baseline and at 1 month of SNM at a frequency of 40 Hz may help to predict the outcome of SNM and thus influence the decision for permanent implantation for @entity1 with @entity322 and @entity1142 .
