Prognostic significance of ventricular late potentials in XXXX .

@entity1 @entity13675 @entity439 @entity2224 @entity453 @entity1455
By means of high-gain ECG and signal-averaging techniques, we tried to determine the prevalence and prognostic significance of ventricular late potentials (VLPs) in @entity453 ( @entity453 ). No VLPs were detected in normal subjects (n = 25) or in @entity1 with @entity13675 with sustained @entity2224 (VT/VF) (n = 10). Among 92 @entity453 @entity1 , VLPs were apparent in 35% (32 of 92) at the beginning of the study. The prevalence of VLPs increased to 48% (19 of 40) in the presence of @entity439 ( @entity439 ) and to 82% (14 of 17) in the presence of a history of previous sustained VT/VF. To determine the prognostic significance of VLPs, a prospective analysis was conducted during a mean of 7.4 months (range 1 to 22 months). During the follow-up period, 11 @entity1 (12%) presented with an episode of sustained VT/VF, and six of them died from documented VT/VF. Three other @entity1 died from @entity1455 . An episode of sustained VT/VF occurred in 31% (10 of 32) of the @entity1 with VLPs vs 2% (1 of 58) of the @entity1 without VLPs (p less than 0.001), and six @entity1 with VLPs died from sustained VT/VF vs none in the group of @entity1 without VLPs (p less than 0.01). This VLP-related increase in arrhythmic risk was still present in the particular subgroup of @entity1 with a history of previous sustained VT/VF (n = 17) and in @entity1 with @entity439 (n = 40). The risk of developing sustained VT/VF was also influenced by the length of the VLP and by a low mean ejection fraction.(ABSTRACT TRUNCATED AT 250 WORDS)
