HRT and XXXX .

@entity1 @entity2931 @entity303 @entity1294 @entity73 @entity179 @entity195
The role of HRT and/or @entity2931 in the aetiology, progression and prevention of @entity179 is unclear. Various studies have been conducted in cells, animals and @entity1 to better define these relationships. The following is a presentation of data on the role of @entity2931 in the two most common @entity303 syndromes @entity195 and @entity1294 . This review examines whether there is support for the hypothesis that the use of @entity2931 reduces the risk for @entity303 and @entity73 in a variety of experimental models. A literature search was performed using the following key words: @entity2931 and @entity303 , @entity2931 and Alzheimer, @entity2931 and cognition, @entity2931 and learning, and @entity2931 and memory. The reference lists for the articles identified using these search strategies were examined. The strongest evidence for a beneficial effect comes from cell and animal studies. These suggest that treatment with @entity2931 may influence the pathogenetic processes of AD, mainly by affecting the beta-amyloid metabolism, by promoting the activity of the cholinergic system, by reducing oxidative stress or cardiovascular risk. Observational studies give some support to the hypothesis that HRT may be protective for @entity73 and @entity303 in the elderly, but the inherited methodological problems in these studies preclude any conclusions. The treatment trials published thus far have methodological problems that prohibit definite conclusions on the relationship between HRT and @entity73 and @entity303 .
