Effects of XXXX pollen ( @entity2484 .) and Astragalus ovinus on sperm parameters and sex hormones in adult male @entity35 .

@entity249 @entity251 @entity14217 @entity53 @entity2484 @entity35
BACKGROUND: @entity2484 Pollen ( @entity14217 ) and Astragalus genus are used in some countries for the treatment of @entity249 . OBJECTIVE: This study was designed to investigate effects of @entity14217 and Astragalus ovinus (A.Ovinus) on fertility in healthy adult male @entity35 . MATERIALS AND METHODS: Thirty-six @entity35 were divided into six groups (n=6) including control and five treatment groups. @entity14217 (120, 240 and 360 mg/kg) and A.ovinus (100, 500 mg/ kg) were orally given to the treatment groups. After thirty-five days, blood samples were taken to determine serum levels of FSH, LH, @entity251 and @entity53 . Weight of testis and epididymis, sperm count, sperm motility, seminiferous tubules diameter (STD), germinal cell layer thickness (GCLT), sertoli, leydig and spermatogonia cells were also evaluated. RESULTS: @entity14217 at the of 120 and 240 mg/kg doses significantly raised the ratio of testis or epididymis to body weight, sperm count, sperm motility , and @entity53 level compared to the control group (p<0.05). LH and @entity251 levels only noticeably increased at 120 mg/kg of @entity14217 (p<0.01 and p<0.001 respectively). STD increased in the three applied doses (p=0.001). A. ovinus extract at the indicated doses produced a significant reduction in the ratio of testis or epididymis to body weight and sperm motility (p<0.05). Sperm count, spermatogonia, leydig cells and FSH level decreased at dose of 500 mg/kg. Furthermore, GCLT, spermatogonia cells, and serum @entity53 level increased at 100 mg/kg dose of A. ovinus. CONCLUSION: Our findings indicate that @entity14217 could improve fertility factors, while A.ovinus can exhibit deleterious effects on gonad and sperm parameters in @entity35 .
