[Prevalence of XXXX types in cervical intraepithelial lesions].

@entity1 @entity10479 @entity5 @entity75 @entity1083 @entity1799 @entity1082
BACKGROUND: Since the implementation of the @entity5 screening program in Lithuania in 2004, @entity5 incidence rates have stabilized during a 4-year period: in 2006 and 2007, 508 and 485 new cases, respectively, were diagnosed. @entity1082 ) infection is one of the main risk factors for @entity5 and development of intraepithelial lesions. However, not only HPV, but also HPV type, is a very important factor for malignant transformation. Cervical intraepithelial lesions with @entity1799 and 18 more frequently progress to @entity5 . To date, in Lithuania, studies only on HPV prevalence and risk factors have been carried out, and less attention has been paid to the identification of HPV types. The aim of this study was to identify the most common HPV types in @entity1 with various cytological lesions. MATERIAL AND METHODS: A total of 246 @entity1 with various cytological lesions ( @entity10479 [ @entity10479 ], low-grade squamous @entity75 [LSIL], and high-grade squamous @entity75 [HSIL]) were included into the study. All the @entity1 were screened for @entity1083 followed by HPV typing for types 6, 11, 16, 18, 31, 33, 45, and 59. Polymerase chain reaction was used. RESULTS: Less than half (45.5%) of @entity1 with cytological lesions were infected with HPV. The highest prevalence of HPV was detected in @entity1 with HSILs (62.1%) and CIN2 (86.7%). HPV typing revealed that the most frequent type was @entity1799 (64.3%); HPV 18 and HPV 33 accounted for 5.4% and 4.5% of cases, respectively. Based on cytologic diagnosis, @entity1799 was more frequently found in @entity1 with HSILs than @entity1 with @entity10479 (77.8% vs. 50.0%). CONCLUSIONS: The prevalence of @entity1083 in @entity1 with cytological lesions was 45.5%. The highest prevalence of HPV was detected in @entity1 with HSILs (cytologic investigation) and CIN2 (histologic investigation). @entity1799 is the most common type in @entity1 with various cervical intraepithelial lesions.
