XXXX content in superior cervical @entity4494 following reinnervation of vagal afferent fibers in cat.

@entity254 @entity4494 @entity1617 @entity468 @entity934
The superior cervical @entity4494 (SCG) was reinnervated by vagal afferent fibers by cross @entity254 between the cranial end of nodose @entity4494 and the caudal end of SCG in @entity468 . Formation of functional synapses was evidenced by unilateral mydriasis and contraction of the nictitating membrane in response to inflation of the stomach with a balloon or to electrical stimulation of the afferent vagus. The @entity934 ( @entity1617 ) content in the cross-anastomosed SCG (reinnervated by vagal afferent fibers) was measured. In anastomosed SCG, the @entity1617 content was about half of normal SCG, but significantly higher than chronically decentralized SCG. Also the @entity1617 content in nodose @entity4494 (NDG) was investigated in situations in which there was @entity254 , chronic supra, infra, or supra-/infranodose vagotomy. The @entity1617 content of anastomosed NDG was near that of supranosdose vagotomized @entity4494 . The @entity1617 content of supra-/infranodose vagotomized NDG, which can be considered the NDG itself, was as much as that of normal intact NDG. It was found that the @entity1617 content of infranodose vagotomized NDG was increased, possibly the result of vagal efferent axonal flow or transport. The @entity1617 content of vagal trunk with or without infranodose vagotomy was also measured. The @entity1617 content of vagal trunk with infranodose vagotomy was smaller than that of the normal trunk, but there was still a considerable quantity of @entity1617 . There was no significant change in wet weight of the SCG and NDG before or after the operations. From these results we have concluded that the transmission of the cross-anastomosed SCG (reinnervated with vagal afferent nerve) was cholinergic; and that the vagal afferent nerve have afferent cell bodies not only in NDG but also in peripheral vagal trunks (infranodose portion). These results strongly suggest that vagal afferent fibers are in part cholinergic.
