Genetic characterisation of drug resistance and clonal dynamics of XXXX in a hospital setting in Mexico.

@entity2892 @entity2177 @entity2889 @entity18717 @entity3524 @entity281 @entity46246 @entity3064 @entity5505
UNASSIGNED: The aim of this study was to determine the clinical characteristics, molecular epidemiology and biofilm production of @entity3064 clinical isolates obtained from a tertiary-care hospital in Mexico. Clinical isolates of A. baumannii (n=152) isolated from 2007 to 2012 were included. Clonal diversity was analysed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Antimicrobial susceptibility was determined using the broth microdilution method. IMP, VIM, NDM and OXA-type genes were screened by PCR. Biofilm production was analysed using the crystal violet method. Mortality attributable to A. baumannii @entity281 was 14.5%. Fifty-four clones were detected, of which five predominated. MLST results showed three new sequence types and two reported sequence types. More than 86% of the isolates were resistant to @entity2177 , @entity5505 and @entity3524 . Furthermore, 50.7% and 35.5% of the isolates were resistant to @entity2892 and @entity2889 , respectively. Of the isolates evaluated, 28.3% and 25.7% were positive for the @entity18717 and @entity46246 genes, respectively. Biofilm production was associated with resistance to @entity2892 (P=0.002).
