Optic Disc Change during Childhood Myopic Shift: Comparison between Eyes with an Enlarged @entity10794 and XXXX Compared to Normal Myopic Eyes.

@entity1 @entity726 @entity2790 @entity194 @entity10794
BACKGROUND: Progressive disc tilting and the development or enlargement of @entity194 ( @entity194 ) are observed during a myopic shift in @entity1 . This could be related to the changes around the optic nerve head during eyeball elongation. If the biomechanical properties at or around the optic nerve head are changed after exposure to @entity2790 (IOP) in @entity726 , different response of the disc tilting and @entity194 changes could take place during eyeball elongation by myopic shift. On the basis of this background, the aim of this study was to compare the morphological changes in the optic disc induced by a myopic shift during childhood between normal control eyes, eyes from disc suspects with an enlarged @entity10794 ( @entity10794 ), and eyes with @entity726 . METHODS: Total of 82 eyes from 82 subjects younger than 14 years of age were included in the study. Serial disc photographs were classified into one of two groups: eyes with an optic nerve head (ONH) or @entity194 ( @entity194 ) change or without an ONH/ @entity194 change. Using ImageJ software, the outlines of the optic disc and @entity194 were plotted, and the vertical disc diameter (VDD), horizontal disc diameter (HDD), and maximum @entity194 width (PPW) were measured. The changes in the ratios of these parameters and the relationships between the degree of myopic shift or the ONH/ @entity194 change were analyzed. RESULTS: Twenty-five eyes with normal optic disc appearance, 36 eyes with enlarged @entity10794 , and 21 eyes of @entity726 @entity1 were analyzed. The @entity2790 (IOP) at diagnosis was significantly different among the groups (P<0.001). The degree of myopic shift during follow-up period was not significantly different among the groups (P=0.612). However, the changes in the HDD/VDD and PPW/VDD ratios were significantly greater in the disc suspect group and significantly smaller in the @entity726 group. Among the 42 eyes with an ONH/ @entity194 change, 16 (38.1%) were from the normal control group, 24 (57.1%) were from the disc suspect group, and 2 (4.8%) were from the @entity726 group (P < 0.001). CONCLUSIONS AND RELEVANCE: The optic disc change during childhood myopic shift was different in eyes with various conditions. Eyes of @entity726 showed less change in the disc morphology during myopic shift compared to eyes with normal disc or enlarged @entity10794 .
