Effectiveness of Early Preventive Intervention with Semiannual XXXX Varnish Application in Toddlers Living in High-Risk Areas: A Stratified Cluster-Randomized Controlled Trial.

@entity1 @entity1547 @entity1388
UNASSIGNED: This study evaluated whether toddlers in an extended preventive program of semiannual @entity1388 varnish applications from 1 year of age had a lower incidence of @entity1547 than those undergoing a standard program. A cohort of 1-year-old @entity1 (n = 3,403) living in multicultural areas of low socioeconomic standing in Stockholm participated in a cluster-randomized controlled field trial with two parallel arms. The @entity1 attended 23 dental clinics. Using the ICDAS II criteria, the examiners recorded @entity1547 at baseline and after 1 and 2 years. The @entity1 in the reference group received a standardized oral health program once yearly between 1 and 3 years of age. The @entity1 in the test group received the same standard program supplemented with topical applications of @entity1388 varnish every 6 months. We compared the test group and the reference group for the prevalence and @entity1547 . At baseline, 5% of the @entity1 had already developed @entity1547 (ICDAS II 1-6). We reexamined the @entity1 after 1 year (n = 2,675) and after 2 years (n = 2,536). Neither prevalence nor @entity1547 increment differed between the groups. At 3 years of age, 12% of the @entity1 had developed moderate and severe @entity1547 (ICDAS II 3-6), with a mean increment of 0.5 (SD 2.4) in the test group and 0.6 (SD 2.2) in the reference group. In conclusion, semiannual professional applications of @entity1388 varnish, as a supplement to a standard oral health program, failed to reduce @entity1547 development in toddlers from high-risk communities.
