Contrast-induced translocational XXXX and @entity4144 in advanced @entity8 .

@entity1 @entity8 @entity6 @entity2865 @entity1372 @entity3157 @entity520 @entity972 @entity2753 @entity4144
BACKGROUND: In @entity1 with advanced @entity8 , administration of effective osmolar agents may lead to @entity2753 , @entity4144 , @entity520 , and intravascular expansion. To our knowledge, osmolar effects of contrast agents in @entity1 with advanced @entity8 have not been previously elucidated. METHODS: This retrospective case series includes 5 @entity1 with advanced @entity8 who underwent diagnostic and/or therapeutic cardiac catheterization and developed @entity2753 . Blood chemistry tests were performed before and after the procedure. @entity2753 is defined as a plasma @entity1372 concentration less than 135 mEq/L (mmol/L). RESULTS: Mean precontrast and postcontrast @entity1372 levels were 138.6 mEq/L (mmol/L) and 122.6 mEq/L (mmol/L), respectively. Plasma @entity972 levels increased after contrast exposure. There was no difference in degree of @entity4144 between @entity1 with and without @entity6 . Plasma @entity3157 levels were noted to decrease after contrast exposure in 4 of 5 @entity1 , with the exception of a @entity1 undergoing continuous ambulatory peritoneal dialysis. There was a strong correlation between dose of contrast administered and change in @entity1372 level, with a correlation coefficient of 0.91. CONCLUSION: These data suggest that large volumes of contrast may result in hypertonic @entity2753 through a dual effect of exogenous fluid dilution and translocation. The fluid translocated from intracellular to extracellular spaces may lead to a decrease in @entity1372 , @entity2865 , and @entity3157 levels. All @entity1 developed @entity4144 , which may be caused by solvent drag and/or passive diffusion, in addition to impaired excretory capacity. @entity1 with advanced @entity8 exposed to large volumes of contrast should be monitored for osmolar-induced chemical changes so that timely postcontrast dialytic therapy can be instituted.
