Combined transcranial direct current stimulation and home-based occupational therapy for XXXX following @entity1779 : a double-blind randomized controlled trial.

@entity1 @entity73 @entity1779
PURPOSE: To investigate the combined effect of transcranial direct current stimulation (tDCS) and home-based occupational therapy on activities of daily living (ADL) and grip strength, in @entity1 with @entity73 following @entity1779 ( @entity1779 ). METHODS: A double-blind randomized controlled trial with one-week follow-up. @entity1 received five consecutive days of occupational therapy at home, combined with either anodal (n   =   8) or sham (n   =   7) tDCS. The primary outcome was ADL performance, which was assessed with the Jebsen-Taylor test (JTT). RESULTS: Both groups improved JTT over time (p   <   0.01). The anodal group improved grip strength compared with the sham group from baseline to post-assessment (p   =   0.025). However, this difference was attenuated at one-week follow-up. There was a non-significant tendency for greater improvement in JTT in the anodal group compared with the sham group, from baseline to post-assessment (p   =   0.158). CONCLUSIONS: Five consecutive days of tDCS combined with occupational therapy provided greater improvements in grip strength compared with occupational therapy alone. tDCS is a promising add-on intervention regarding training of @entity73 . It is well tolerated by @entity1 and can easily be applied for home-based training. Larger studies with long-term follow-up are needed to further explore possible effects of tDCS in @entity1 with @entity1779 . Implications for Rehabilitation Five consecutive days of tDCS combined with occupational therapy provided greater improvements in grip strength compared with occupational therapy alone. tDCS is well tolerated by @entity1 and can easily be applied for home-based rehabilitation.
