XXXX O157:H7 @entity294 in a nursing home: clinical, epidemiological, and pathological findings.

@entity548 @entity63 @entity526 @entity294 @entity1661 @entity281 @entity4092 @entity158 @entity1381 @entity204 @entity5163
In September 1984, an outbreak of @entity526 O157:H7 @entity281 occurred in a nursing home. It was the first recognized outbreak of this organism in the United States since 1982, when two outbreaks led to its recognition as a pathogen. Thirty-four of 101 residents developed a @entity5163 ; 14 were hospitalized with a severe illness characterized by crampy abdominal @entity158 , marked @entity1661 , and grossly bloody @entity294 , and four died. The spectrum of illness associated with the @entity281 was broad and included the following: @entity4092 , nonbloody @entity294 , @entity548 , @entity1381 , and @entity204 . Clinical, radiographic, and postmortem pathological findings suggested involvement of the cecum and right colon. No evidence of response to antimicrobial agents could be documented, and antidiarrheal agents may have aggravated the disease. This investigation implicated hamburger as the vehicle transmission. Seventeen of 19 residents with @entity548 , but only 28 of 67 healthy residents, had eaten hamburger on 13 September (P less than .001, Fisher's two-tailed exact test; relative risk [RR] = 7.7). Infection with @entity526 O157:H7 can cause a wide range of manifestations. In the elderly these can be particularly severe and may resemble @entity63 .
