Oro-facial XXXX --a clinical and pathological analysis.

@entity1 @entity1501 @entity738 @entity8884 @entity344 @entity7748 @entity7993 @entity460 @entity2883 @entity370 @entity30
A study of 60 @entity1 with oro-facial @entity2883 has been conducted and the clinical presentation of this disorder defined. It encompasses the previously recognised clinical entities of @entity7748 and @entity7748 . The pathological features of the disease are lymphoedema and the presence of multiple non-caseating giant cell granulomata. These granulomata are histologically indistinguishable from those found in both @entity344 and @entity7993 . Within this series of @entity1 , nine had evidence suggestive of @entity344 , and in six this was confirmed. A diagnosis of @entity370 was made in a further two @entity1 . The relationship of oro-facial @entity2883 to these systemic @entity738 is not yet clear. @entity1 with oro-facial @entity2883 who have @entity344 should be investigated for the presence of @entity344 . Those without symptoms should be investigated for evidence of @entity8884 or serological evidence of @entity30 . Within the present study, the erythrocyte sedimentation rate, full blood count, corrected whole blood @entity1501 , serum albumin and @entity460 were the most sensitive markers of @entity344 . @entity370 should be considered in all @entity1 with oro-facial @entity2883 . The absence of clinical signs suggestive of @entity370 , a normal chest radiograph and normal levels of serum angiotensin-converting enzyme makes @entity370 unlikely.
