Different post label delay cerebral blood flow measurements in XXXX with @entity195 using 3D arterial spin labeling.

@entity1 @entity1005 @entity195
PURPOSE: To evaluate cerebral blood flow (CBF) in @entity1 with @entity195 ( @entity195 ) using a three-dimensional pseudocontinuous arterial spin labeling (PCASL). We aimed to study the effects of different post label delay on the resulting CBF maps and to investigate the characteristics and clinical applications of brain perfusion. MATERIALS AND METHODS: Sixteen @entity195 @entity1 and nineteen healthy control subjects were recruited. 3D PCASL was performed using a 3.0T MR scanner. ASL was performed twice with different @entity1005 ( @entity1005 ). Comparisons of CBF were made between @entity195 @entity1 and healthy control subjects respectively with @entity1005 of 1.5s and @entity1005 of 2.5s. Relationship between the CBF values and cognition was investigated using correlation analysis. A receiver operating characteristic (ROC) curve was generated for CBF measurements in posterior cingulate region. RESULT: @entity195 @entity1 with @entity1005 of 1.5s showed lower CBF values primarily in bilateral temporal lobes, precuneus, middle and posterior cingulate gyri, left inferior parietal gyrus, left angular gyrus and left superior frontal gyrus. Lowered cerebral values were also observed in similar regions with @entity1005 of 2.5s, but the clusters of voxel were smaller. CBF values were associated with cognition scores in most of gyri mentioned above. CONCLUSION: Hypoperfusion areas were observed in @entity195 @entity1 . @entity1005 of 1.5s was sufficient to display CBF. Considering the complicated @entity195 pathology, multiple PLDs are strongly recommended.
