Colonic disease site and perioperative complications predict need for later intestinal interventions following intestinal resection in pediatric XXXX .

@entity1 @entity254 @entity30
INTRODUCTION: We studied variables associated with outcomes following intestinal resection for @entity30 . METHODS: A retrospective review of a prospectively maintained single surgeon database was performed. Outcomes evaluated included disease recurrence, need for further resection/dilatation, and complications. Explanatory variables included: anatomical region of resection, open or laparoscopic approach, surgical procedure, technique of @entity254 , number of anastomoses, use of biological therapy, resection margin disease, age at resection, and period (quartile) in series. RESULTS: 81 @entity1 had 100 resections at a median age 14.5years with a median follow-up of 7.7years. Overall complication rate was 22%. Of the 77 @entity1 with no prior resection, 40 (52%) had disease recurrence, and 24 (31%) underwent further resection or dilatation. None of the explanatory variables predicted complications. Disease recurrence was significantly associated with younger age at first resection but not duration of follow-up. The probability of further intestinal intervention was strongly associated with disease site and complications. Odds ratio for further surgery for colonic disease site compared to ileocecal disease site was 7 (95% CI 1.8-26; P=0.004). Odds ratio for further intestinal resection following surgery where a complication had occurred compared to no complication was 3.4 (95% CI 1.1-10.3; P=0.02. Both disease site and complication status also significantly affected the interval to further surgery. CONCLUSIONS: The probability of requiring a second intestinal intervention for pediatric @entity30 is related to the disease site and the complication status.
