[Efficacy analysis of endoscopic endonasal transsphenoidal surgery for recurrent or regrowing XXXX ].

@entity1 @entity5 @entity977
OBJECTIVE: To analyze the safety and efficacy of surgical removal of recurrent or regrowing @entity977 by endoscopic endonasal transsphenoidal approach. METHODS: The clinical data were retrospectively reviewed for 28 @entity1 undergoing endoscopic endonasal transsphenoidal surgery for recurrent or regrowing @entity977 between April 2010 and December 2013. There were 9 males and 19 females with a mean age of 44. 2 (11 - 73) years. The maximal @entity5 diameter ranged from 2. 1 to 6.9 cm. The Knosp grades were 1 -2 (n = 11), 3 (n =8) and 4 (n =9). Fifteen @entity5 were endocrinically functional and the remainder endocrinically nonfunctional. All operations were performed with an assistance of intraoperative neuronavigation. Neuro-ophthalmological, neuroimaging and endocrinological results were followed up postoperatively. And surgical outcomes and risk factors were analyzed for incomplete @entity5 resection in previous operations. RESULTS: The mean follow-up period was 19. 1 (3 - 45) months. Gross total resection(n = 18, 64. 3%), subtotal resection(n = 6, 21. 4%) and partial resection(n = 4, 14. 3%) were achieved. Postoperatively, visual acuity improved in 11 @entity1 (73. 3%) and 6 @entity1 (40. 0%) showed endocrine remission. Qne @entity1 had short-term postoperative leakage of cerebrospinal fluid (CSF). CONCLUSION: Endoscopic endonasal transsphenoidal surgery is both safe and effective for recurrent or regrowing @entity977 .
