[Results of a cooperative prospective study of treatment of primary digestive localizations of XXXX ].

@entity1 @entity632 @entity706 @entity6595 @entity5 @entity229 @entity786 @entity25878 @entity1891 @entity1893
We report the results of chemotherapy treatment in 82 @entity1 presenting with primary digestive lymphoma and included in a study conducted between October 1977 and October 1985. There were 31 @entity6595 , 18 small @entity706 , and 19 with multiple involvement: 63 @entity1 had had a surgical staging with total @entity5 resection in 15 cases. Nineteen @entity1 with limited disease ( @entity25878 and IID) were randomly assigned to either a 3-week chemotherapy regimen associated with whole abdominal radiotherapy or chemotherapy for 3 years. Twenty-seven stage IIID and thirty-six stage IV were treated with chemotherapy alone for 3 years. @entity1893 (16 @entity1 ) received a @entity786 , @entity1891 , @entity229 association. Intermediate (56 @entity1 ) and high grade (10 @entity1 ) @entity706 received @entity786 , @entity1891 , @entity632 , @entity229 . The overall complete remission obtained was 63 p. 100 (51 @entity1 ) with 17 @entity1 in relapse within 6 to 40 months. Overall survival was 46 p. 100 at 5 years. Survival was dependent on abdominal extension, histologic grade according to the new working formulation used for lymph-node @entity706 , initial localization ( @entity6595 have the best survival) and achievement of complete remission. Chemotherapy is an effective treatment for primary @entity706 . The role of surgery in the management of @entity706 has to be defined by further studies.
