Endovascular interventions in advanced XXXX .

@entity1 @entity1204 @entity632 @entity5 @entity900 @entity786 @entity189 @entity26467 @entity74 @entity432
PURPOSE: The primary endpoint of this study was to estimate the efficacy of endovascular interventions - @entity26467 - (occlusion and chemoinfusion of the internal iliac arteries- IIA) in the control of bleeding of @entity1 with advanced cervical and @entity1204 . @entity5 response and survival were also estimated. @entity1 AND METHODS: @entity26467 were carried out in 95 @entity1 with advanced @entity189 (study group). In 82 (86%) of them @entity26467 preceded primary radiotherapy. Autoclots, Ivalon, and Gelfoam were used for @entity432 . In 43 @entity1 intraarterial chemotherapy was followed by occlusion of the internal iliac arteries (IIA). For chemoinfusion, @entity900 (120 mg/m(2)), and later the combination of @entity900 , @entity632 and @entity786 (CAP) were administered into the femoral artery using the Seldinger method. These @entity1 were compared with a similar group of 143 @entity1 treated with radiotherapy alone (control group). RESULTS: Bleeding was controlled by embolization in all 95 @entity1 with @entity26467 and in 122 (85.3%) @entity1 of the control group (p <0.01). Repeat angiographic studies in @entity1 undergoing chemoembolization showed complete remission (CR) in 7%, partial remission (PR) in 63% and disease stabilization (SD) in 30% of the @entity1 . The corresponding figures for the control group were 5%, 54% and 23%, while @entity74 ( @entity74 ) was observed in 18% of the @entity1 of this group. The 3-year overall survival was 47% versus 36% in the study and control groups, respectively (p <0.01). CONCLUSION: @entity26467 is a method effective in stopping bleeding in @entity1 with advanced @entity189 . Chemoembolization of the IIA increases the efficacy of subsequent radiotherapy in @entity1 with advanced @entity189 .
