Hysteroscopy and @entity7548 on experimental sterilization of XXXX uterine tubes.

@entity3080 @entity95 @entity12520 @entity7548 @entity121
PURPOSE: To assess the sterilization effectiveness on uterine tube of @entity95 by the @entity3080 adhesive. METHODS: Hysteroscopy tubal catheterization was performed randomly in 12 animals (24 uterine tubes) assigned to the sham group (GS) and 15 animals (30 uterine tubes) to the @entity7548 (GB). The female @entity95 were observed during 30, 90 and 180 days and mated to fertile males. The no pregnant @entity95 were submitted to in vitro burst pressure test for patency by air insufflation (40 mmHg). The microscopic assessment was performed to parameters of damages in epithelium caused by the adhesive, the degree of inflammatory process, morphometry data values of tube diameter (UT) (cm), @entity12520 ( @entity121 ) (mm). The mucosa cells densitometry (total optical density) was expressed by the amount of DNA. The significance of the differences in histological scores and in thickness measurements were made by ANOVA test (P value < 0.05). RESULTS: In all animals of GB: the adhesive was attached to the mucosa; there was no pregnancy; no records of significant degree on inflammatory process; the patency test was negative and densitometry of DNA showed similar values to the both groups independently of observation periods. The layers thickness of GB-UT(1.118 +/- 0.117), GB-MT(0.447+/-0.247) and GB- @entity121 (0.853+/-0.097) were larger than the GS-UT(0.666+/-0.409), GS-MT(0.211+/-0.070) and GS- @entity121 (0.442+/-0.143). CONCLUSION: This approach offers a safe and feasible method of uterine tube obstruction.
