XXXX of the mandible.

@entity5 @entity2828 @entity79 @entity158
@entity2828 is an uncommon @entity5 that primarily occurs in the long bones of the lower and upper extremities. Only 2% involve the mandible, and the maxilla is involved one eighth as often as the mandible. The most common site of metastases is the lung. Increasing @entity158 is the most common presenting symptom. A case of mandibular involvement is presented. The combination of a large, soft tissue mass adjacent to an area of @entity79 in a young male should suggest the diagnosis. The previously poor five- and ten-year survival rates of 8 and 4% respectively, may have promise of marked improvement. This improvement lies in a changing philosophy of treatment. Four-drug chemotherapy combined with prophylactic whole-lung irradiation has been added to local irradiation of the @entity5 bed. Five-year survival figures of 20 to 30% appear obtainable. Although extensive surgical resection of the @entity5 in the long bones has for the most part been replaced by local irradiation for control, surgery in mandibular cases may still be the treatment of choice.
