[The protective effect and mechanism of XXXX preconditioning for hepatic resection under hepatic blood inflow occlusion in @entity157 @entity1 with @entity82 ].

@entity1 @entity2313 @entity82 @entity5524 @entity522 @entity6571 @entity63 @entity773 @entity157
OBJECTIVE: To investigate the protective effect of @entity63 preconditioning (IPC) for hepatic resection under hepatic blood inflow occlusion (HBIO) in @entity157 @entity1 with @entity82 and its possible mechanism. METHODS: 29 consecutive @entity1 resectable @entity157 were randomized into two groups. @entity5524 group: before HBIO, IPC with 5 min of @entity63 and 5 min of reperfusion was given; control group: simple HBIO. The liver function, hepatic @entity522 activity, and apoptotic cell were compared between the two groups. RESULTS: The @entity6571 , ALT levels of @entity773 , POD 3 and POD 7 in the IPC group were significantly higher than those of the control group, respectively (t = 4.238, P < 0.05). The TBIL levels of POD 3 and POD 7 in the IPC group were significantly higher than those of the control group, respectively (t = 2.296, P < 0.05). The @entity2313 of @entity773 in the IPC group was higher than in the control group (t = 2.029, P > 0.05). After 1 h of reperfusion, the hepatic @entity522 activity and apoptotic sinusoidal endothelial cell were significantly higher than those of in the control group (t = 2.349, P < 0.05). CONCLUSIONS: IPC has the a protective effect in hepatic resection under HBIO in @entity157 @entity1 with @entity82 . Its mechanism is that sinusoidal endothelial cell apoptosis is inhibited by inhibiting @entity522 activity.
