Effects of extra-corporeal shock waves on penile hemodynamics and histopathology in XXXX .

@entity5377 @entity548 @entity1711 @entity1710 @entity35 @entity551
AIM: To study the effect of extra-corporeal shock wave (ESW) on the penile hemodynamics and histopathology in @entity35 . METHODS: Adult male @entity35 were divided at random into 3 groups. ESW application was performed with a @entity5377 Lithostar with the @entity35 under anesthesia lying prone on the balloon probe. @entity35 in Group I received a total of 1000 shocks at 18 kV and immediately underwent hemodynamic evaluation performed by direct electrostimulation of the cavernous nerve and measurement of @entity551 ( @entity551 ). @entity35 in Group II received 3 times 1000 shocks at 18 kV at weekly intervals and hemodynamic evaluation was performed 1 month after the last ESW application. Group III served as the control. Histopathological examinations of penile tissues were done on Masson's trichrome and @entity1710 and @entity1711 stained sections. RESULTS: Penile hemodynamic evaluation showed a trend toward a diminished mean maximal @entity551 , duration of erection, @entity551 during the plateau phase and maximal @entity551 / blood pressure ratio in Group I, although there was no significant significance. The mean latency period in Groups I and II was prolonged. Petechial bleeding within tunical layers and small foci of @entity548 within the corpora cavernosa were observed in Group I. However, histopathological examination failed to reveal any significant differences between the groups in terms of smooth muscle content, tunical thickness, organization of collagen bundles and elastic fiber-lattice framework. CONCLUSION: ESW has certain damaging effects on the penis.
