Green Tea Extract Rich in @entity3089 Prevents Fatty Liver by AMPK Activation via XXXX in @entity19 Fed a High-Fat Diet.

@entity844 @entity33134 @entity28 @entity19 @entity2448 @entity4062 @entity3089 @entity58728 @entity23 @entity1561 @entity1017 @entity14075
UNASSIGNED: Supplementation with @entity3089 has been determined to aid in the prevention of @entity28 . Decaffeinated green tea extract appears to restore a normal hepatic metabolic profile and attenuate high-fat diet (HFD)-induced effects, thereby preventing @entity1561 in @entity19 . @entity19 were maintained on either a @entity23 ( @entity23 ) or HFD for 16 weeks and supplemented with either water or green tea extract (50 mg/kg/day). The body mass increase, serum adiponectin level, and lipid profile were measured over the course of the treatment. Furthermore, the AMPK pathway protein expression in the liver was measured. From the fourth week, the @entity1017 in the @entity23 + green tea extract (CE) group was lower than that in the @entity23 + water (CW) group. From the eighth week, the @entity1017 in the HFD + water (HFW) group was found to be higher than that in the CW group. Moreover, the @entity1017 in the HFD + green tea extract (HFE) group was found to be lower than that in the HFW group. Carcass lipid content was found to be higher in the HFW group than that in the CW and HFE groups. Serum analysis showed reduced non-esterified @entity844 level in the CE and HFE groups as compared with their corresponding placebo groups. Increased adiponectin level was observed in the same groups. Increased VLDL-TG secretion was observed in the HFW group as compared with the CW and HFE groups. Increased protein expression of @entity58728 , @entity14075 , pLKB1, and pAMPK was observed in the HFE group, which explained the reduced expression of ACC, FAS, @entity4062 , and @entity33134 in this group. These results indicate that the effects of decaffeinated green tea extract may be related to the activation of AMPK via @entity2448 in the liver of HFD-fed @entity19 .
