Endovascular reconstruction of unruptured intradural vertebral artery dissecting XXXX .

@entity1 @entity64 @entity438 @entity439 @entity1031 @entity432 @entity4653
BACKGROUND: Dissecting @entity438 (VA) are difficult to treat using current surgical and endovascular techniques. OBJECTIVE: To analyze retrospectively the efficacy and safety of flow diverters in the treatment of dissecting @entity438 . METHODS: We identified six @entity1 with six unruptured VA dissecting @entity439 either arising from the V4 or V3-V4 junction that were treated with the Pipeline embolization device (PED) at our institution between July 2012 and February 2015. Among other parameters, technical feasibility of the procedure, procedure-related complications, angiographic results, and clinical outcome were evaluated. RESULTS: PED placement was achieved in all cases and immediate angiography follow-up demonstrated intra-aneurysmal contrast stasis with parent artery preservation. A temporary episode of @entity4653 was noted in one @entity1 . Major procedure-related complications were not observed. The 6-month follow-up (n=6) demonstrated complete/near-complete @entity439 in five @entity1 and partial obliteration in one. At the 1-year follow-up (n=5) stable complete @entity439 was seen in two @entity1 . Two cases showed progression from near complete @entity432 and partial @entity432 at 6 months to complete @entity432 and near complete @entity432 . One cases showed unchanged near complete @entity432 . No @entity439 , in-stent stenosis or @entity1031 complication was seen. National Institutes of Health @entity64 Scale and modified Rankin scale scores remained unchanged from admission to discharge. CONCLUSIONS: Our preliminary experience with the use of PED for the treatment of intradural VA dissecting @entity439 shows promising short-term results, making this technique a feasible and safe treatment option in @entity1 suitable for this approach. However, long-term and larger cohort studies are needed to validate these results.
