Cryotherapy of XXXX under ultrasound guidance: initial results and limitations.

@entity1 @entity3821 @entity0 @entity39 @entity5 @entity3
The aim of this study was to investigate the potential and feasibility of ultrasound-guided cryotherapy in @entity0 . Fifteen female @entity1 with 16 @entity0 (mean @entity5 diameter 21+/-7.8 mm) were treated. A 3-mm cryo probe was placed in the @entity5 under ultrasound guidance. Two freeze/thaw cycles with durations of 7-10 min and 5 min, respectively, were performed. The size of the iceballs was measured sonographically in 1-min intervals. The @entity1 underwent surgery within 5 days and the specimens were evaluated histologically. The mean diameter of the iceball was 28+/-2.7 mm after the second freezing cycle. No severe side effects were observed. @entity5 with a diameter below 16 mm did not show any remaining @entity3 after treatment. Two of these had @entity3821 ( @entity3821 ) in the surrounding tissue. In 11 @entity1 cryotherapy of @entity5 reaching diameters of 23 mm or more resulted in incomplete @entity39 . This study shows that the invasive components of small @entity5 can be treated using cryotherapy. Remnant @entity3821 components which may not be detected preinterventionally represent a challenging problem for complete ablation. In @entity5 larger than 15 mm two or more cryo probes should be used to achieve larger iceballs.
