Role of @entity1289 inhibitors, @entity2178 receptor blockers, and @entity1369 antagonists in the prevention of XXXX .

@entity1164 @entity1 @entity712 @entity1369 @entity1289 @entity101 @entity2178 @entity4346 @entity955 @entity583 @entity943 @entity1002
@entity943 , @entity943 , and @entity1164 ( @entity1164 ) are significant health problems and an economic burden to society. The renin-angiotensin- @entity1369 system (RAAS) may play a key role in the occurrence of structural and electrical remodeling, potentially explaining the development of @entity943 . @entity2178 has been shown to regulate cardiac cell proliferation and to modulate cardiac myocyte ion channels. Results of post hoc analyses from prospective clinical trials appear to show that @entity1289 ( @entity1289 ) inhibitors and @entity2178 receptor blockers (ARBs) are most effective in the prevention of new-onset @entity955 in @entity1 with @entity712 . It is difficult to determine if these agents are useful in the prevention of new-onset @entity955 after @entity583 , and available evidence suggests that the benefit of @entity1289 inhibitors and ARBs for prevention of new-onset @entity955 in @entity1 with @entity101 appears limited to those with @entity4346 . @entity1 with structural changes in cardiac muscle, such as those with @entity712 and @entity4346 , appear to benefit the most from RAAS blockade, possibly due to the theory of reversal of cardiac remodeling. There is no evidence, to our knowledge, that either @entity1289 inhibitors or ARBs facilitate direct electrical current cardioversion in @entity1 with @entity955 ; however, it appears that RAAS blockade may be useful in the prevention of recurrent @entity955 after direct electrical current cardioversion. Whether @entity1289 inhibitors may prevent life-threatening @entity943 or @entity1164 is unclear. @entity1369 antagonists appear to be useful for the prevention of @entity1164 in @entity1 with @entity1002 . Results from ongoing clinical trials are anticipated to provide further insight on the potential roles of RAAS inhibitors for the prevention of @entity943 .
