Frequency and risk of XXXX in prediabetics versus normal @entity413 tolerant subjects - a comparative study.

@entity1 @entity101 @entity6 @entity1674 @entity1144 @entity65 @entity209 @entity413
OBJECTIVE: To compare the frequency and risk of @entity209 in @entity6 against normal @entity413 -tolerant subjects attending @entity6 screening camps in an urban centre. METHODS: The cross-sectional study was carried out at the Jinnah Postgraduate Medical Centre, Karachi, from January to August, 2008, and comprised subjects recruited through @entity6 screening camps. They were >30 years of age, without prior history of @entity6 and were screened through fasting plasma @entity413 and 2-hour oral @entity413 tolerance test. Demographic, anthropometric, clinical and biochemical measurements were done. Frequency of different components and their constellation as @entity209 were determined according to the Adult Treatment Panel-III criteria. Relative risk was estimated to find the risk of @entity209 in @entity6 versus normal @entity413 -tolerant subjects. RESULTS: The study sample comprised 80 subjects; 40(50%) normal @entity413 -tolerant in Group A and 40(50%) @entity6 in Group B. In Group A, there were 25(62.5%) @entity1 and 15(37.5%) @entity1 , while Group B had 22(55%) @entity1 and 18(45%) @entity1 . The mean age in Group A was 38.08  5.35 years, while in Group B it was 39.09  6.12 years. The frequency of various cardiovascular risk factors was higher in @entity6 (p< 0.05). @entity1144 was the most prevalent risk factor (85%, CI: 75.74-96.06), followed by low levels of high density lipoprotein (82.5%, CI: 72.64-94.27), raised @entity1674 (67.5%, CI: 55.35-82.01), @entity101 (57.5%, CI: 44.68-72.82), and fasting plasma @entity413 >100mg/dl (42.5%, CI: 29.68-57.82). @entity209 was found in 23(57.5%) in Group B compared to 9(22.5%) Group B, according to Adult Treatment Panel-III criteria. Calculated relative risk indicated that Group B was 1.9 times more prone to be suffering from @entity209 compared to Group A. CONCLUSIONS: Pre- @entity6 were more prone to developing @entity65 than normal @entity413 -tolerant subjects.
