Basal Pain Sensitivity does not Predict the Outcome of XXXX Treatment.

@entity1 @entity308 @entity148 @entity158 @entity1118
OBJECTIVES: Individual differences in underlying, "basal" @entity158 sensitivity are large and have clinical implications. Some studies have suggested that @entity158 sensitivity may also predict the outcome of @entity158 treatment. @entity1118 management programs are effective, but treatment success is individually very different. Therefore, identification of predictors of treatment success is important. This study investigated if @entity158 sensitivity predicted the outcome of a 4-week outpatient multidisciplinary @entity158 management program. DESIGN: Cohort study. SETTING: @entity1118 outpatient clinic at the Department of Anesthesiology, Intensive Care Medicine and Pain Therapy of the University of M  nster. METHODS: @entity158 sensitivity was measured at treatment onset, using comprehensive experimental @entity158 testing (thermal, pressure, and @entity158 ) and the @entity158 sensitivity questionnaire. Primary (clinical @entity158 intensity) and secondary ( @entity308 , @entity148 , @entity158 ) outcome parameters were assessed at treatment start, at discharge and 6 months later. SUBJECTS: Sixty five adult chronic @entity158 @entity1 with mixed @entity158 diagnoses. RESULTS: There were significant improvements in clinical @entity158 intensity (from 6.1        2.0 to 5.1        1.8 [0-10]), @entity308 and @entity148 at discharge (all P   <   0.001) and of clinical @entity158 intensity (to 5.3        2.3 [0-10]) and @entity158 at 6 months (all P   <   0.05). However, treatment outcome was not predicted by any of the @entity158 sensitivity measures. DISCUSSION: Results show that @entity158 sensitivity is not a reliable predictor of treatment outcome in mixed diagnosis multidisciplinary @entity158 management programs, possibly due to the heterogeneity of @entity1 enrolled in such programs. Clinically useful predictors of treatment success in this setting remain to be identified.
