XXXX defines secretions from salivary tissue in post-Sistrunk procedure drainage.

@entity1 @entity5089 @entity11677 @entity7571
OBJECTIVES: This was a pilot study to establish a protein difference between @entity11677 fluid relative to oral saliva, in order to differentiate @entity1 with residual thyroglossal cyst from those with salivary fistula in the case of post-Sistrunk procedure incisional drainage. Past immunohistochemistry studies on archived tissue blocks from post-Sistrunk procedure @entity1 have shown @entity5089 to have elevated concentrations in thyroglossal duct relative to salivary tissue; secretory @entity7571 ( @entity7571 ) was also chosen as a candidate protein based on previously published reports of its increased concentration in saliva relative to respiratory secretions. DESIGN: Diagnostic tests were assessed. Thyroglossal duct cyst fluid and oral saliva were obtained from 12 @entity1 . Enzyme-linked immunosorbent assay (ELISA) was then performed on the samples to identify the presence of @entity5089 and @entity7571 . SETTING: Tertiary care hospital. SUBJECTS: @entity1 fluid samples were taken immediately postoperatively for @entity1 undergoing Sistrunk procedure at one institution. Presence of @entity11677 was confirmed in all cases by pathology. RESULTS: Seven of 12 @entity11677 fluid samples were shown to have elevated absorbance with ELISA for @entity5089 . In experiments for @entity7571 , 10 of the 12 saliva samples had elevated absorbance compared with thyroglossal duct fluid samples obtained from the same @entity1 . CONCLUSIONS: @entity7571 is an accurate identifier of saliva compared with thyroglossal duct fluid in secreted samples obtained from the same @entity1 .
