Immunohistochemical characterization of endocervical XXXX .

@entity1 @entity1377 @entity588 @entity146 @entity5 @entity787 @entity876 @entity2282 @entity1478 @entity420
Endocervical @entity420 are rare and aggressive @entity5 . Papillary serous endocervical @entity420 are the rarest form of endocervical @entity420 . This @entity5 exhibits morphologic similarities to its counterparts commonly seen in the endometrium, fallopian tubes, ovaries, and peritoneum, which are known to have an @entity146 . Because of the rarity of this @entity5 , little is known about its immunophenotyping. In this study, we included ten cases of @entity1377 arising from the uterine cervix (PSCC) diagnosed in the absence of a primary @entity1478 . We studied their immunohistochemical profile, using a panel of antibodies against Ki67, @entity588 , @entity876 , @entity787 ( @entity787 ), and @entity2282 , and compared them to 20 consecutive cases of cervical @entity420 of conventional cell subtypes (CAC) (15 mucinous, 3 adenosquamous, and 2 endometrioid). Immunostaining was recorded semiquantitatively. @entity1 with PSCC ranged in age from 27 to 79 years (mean = 51.6 +/- 19.1), while the conventional cell subtypes control group were 28-90 years old (mean = 47.5 +/- 16.9). Only @entity876 and @entity787 immunostaining significantly correlated with the PSCC morphology (P= 0.001 and P= 0.016, respectively) as shown by Cochran-Mantel-Haenszel Statistics (Modified Ridit Scores). PSCC is a distinctive immunophenotypic subtype of @entity420 with significantly higher @entity876 and lower @entity787 reactivity than other more common histologic subtypes.
