Presentations of pyogenic XXXX in one UK centre over a 15-year period.

@entity5572 @entity1 @entity295 @entity353 @entity5 @entity1989 @entity391 @entity448 @entity490 @entity221 @entity1851
BACKGROUND AND AIM: Pyogenic @entity5572 ( @entity1989 ) has been a condition of high mortality, improving over recent decades with combined antibiotic and percutaneous drainage. We aimed to identify the presenting features, diagnosis, microbiology, treatment and outcome for @entity1 over a 15-year period at an inner-city hospital. METHODS: @entity1 with an appropriate discharge diagnosis were identified and case records retrospectively analysed. RESULTS: A total of 73 @entity1 records were analysed. Common presenting features were @entity448 , @entity490 , @entity221 , @entity391 and @entity353 with raised white cell count, @entity1851 , alkaline phosphatase and hypoalbuminaemia. The delay following symptom onset to presentation was a mean of 17.3 days. The inclusion of @entity1989 as a possible diagnosis on admission was only considered in 1% of cases. Positive blood or abscess culture was achieved in 63% of cases. We recorded a hospital mortality rate of 11%. CONCLUSIONS: In this sample, @entity1989 was rarely considered as a possible diagnosis at presentation. There are common presenting features, which should prompt early investigation. Our microbiological yield was lower than in some studies and may be due to the early empirical use of antibiotics, without microbiological guidance. Percutaneous drainage and antibiotic treatment remain the mainstay of management. The underlying cause for @entity1989 is often not identified. Emerging @entity295 or underlying @entity5 were strong predictors of mortality.
