Long-term cardiopulmonary sequelae in @entity1 with XXXX and @entity1030 .

@entity1 @entity6700 @entity387 @entity3618 @entity26 @entity120 @entity27 @entity519 @entity358 @entity1030 @entity386
Both @entity27 and @entity1030 can be associated with intermittent or chronic @entity519 leading to @entity120 and @entity3618 . When these problems coexist, it is possible that the cardiopulmonary effects are additive. We hypothesized that hemodynamic disturbances in @entity1 with @entity358 would be more severe than in those with @entity386 alone, and that hemodynamic improvement should follow @entity386 cure, but perhaps at a slower rate than in those with @entity386 alone. To test these hypotheses, we prospectively followed 24 @entity1 with @entity387 . They were divided into 3 nonrandomized groups. Nineteen @entity1 had both @entity358 . Nine of these agreed to curative tracheostomy (Group 1). The other 10 subjects (Group 2) refused tracheostomy but accepted noncurative therapies, including nocturnal @entity26 (n = 9), uvulopalatopharyngoplasty (n = 2), and @entity6700 (n = 4). Five subjects with @entity386 but without clinically obvious @entity358 received tracheostomies (Group 3). Subjects were followed at yearly intervals (mean follow-up, 27.2 months) with radionuclide motion studies and, in 15 of 24 who consented, right heart catheterization. The 3 groups did not vary with respect to age, percent ideal weight, or severity of @entity386 symptoms. The severity of right-sided hemodynamic dysfunction in the group with @entity386 but no obvious @entity358 was less than that in the 2 groups with @entity358 . A substantial decrease in pulmonary artery pressure (p = 0.056) and significant improvement in right ventricular ejection fraction occurred in the tracheostomized group with both @entity358 . Pulmonary vascular resistance decreased in both groups receiving tracheostomy.(ABSTRACT TRUNCATED AT 250 WORDS)
