Successful Living-Donor Liver Transplantation for Cholestatic @entity1578 Induced by XXXX : Case Report.

@entity1 @entity8 @entity99 @entity1087 @entity3265 @entity648 @entity1578 @entity208
A 39-year-old @entity1 was diagnosed with @entity208 -induced @entity99 . He did not show any sign of @entity99 , but his serum total @entity648 level was >40  mg/dL when he visited the local hospital. The therapeutic effects of initial medical treatments were transient, and both renal function and coagulation ability were gradually deteriorated. Four months after the onset of @entity99 , he was referred to our hospital for the purpose of liver transplantation (LT). Although he was wasting and severely @entity1087 , his consciousness level was not disturbed at all, with normal serum @entity3265 blood concentration before LT. Owing to @entity208 -induced severe @entity1578 , living-donor LT (LDLT) was performed with the use of a right lobe graft from his younger brother. The explanted liver was extremely enlarged, with a weight of 2,480 g, and severely cholestatic. Microscopic findings were also compatible with drug-induced @entity99 . He was discharged from hospital 55 days after LDLT, whereas his @entity8 remained at 6 months after LT. There are 3 types of pathophysiology of drug-induced hepatotoxicity: hepatocellular, cholestatic, and mixed @entity99 . Although @entity208 hepatotoxicity is rare, it can be severe and even fatal. This is the 1st case report of successful LDLT for a @entity1 who had developed @entity208 -induced @entity1578 .
