[A @entity1 with Probable @entity303 with Lewy Bodies and Positive Autoantibodies against the Anti- XXXX <sub>2</sub>-terminal of a-Enolase].

@entity1 @entity1375 @entity3034 @entity3264 @entity146 @entity303 @entity73 @entity5155 @entity1955 @entity7336 @entity14752 @entity1832 @entity179 @entity792
@entity1832 ( @entity1832 ) is clinically characterized by progressive @entity303 that is frequently accompanied by neurological and @entity146 manifestations. @entity14752 ( @entity14752 ) is a rare @entity792 with neurological and @entity146 manifestations that is not well understood. However, this disease has attracted growing attention as a treatable @entity303 . Although autoimmune mechanisms are thought to play a pathogenic role in @entity14752 , the etiology of the disease remains unclear. Recently, it was reported that the serum in @entity1 with @entity14752 is frequentry positive for autoantibodies against the anti- @entity5155 <sub>2</sub>-terminal of a-enolase (anti-NAE), indicating a useful serological diagnostic marker for @entity14752 . We report the case of an 81-year-old Japanese @entity1 with probable @entity1832 and @entity1375 . In her serum, elevated anti-thyroid antibodies and positive autoantibodies against anti-NAE were observed. Elevated levels of anti- @entity3264 receptor   2 subunit ( @entity7336 ) antibodies were also detected in her cerebrospinal fluid. Because her clinical condition became stable after treatment with cholinesterase inhibitor, @entity3034 , and @entity1955 , immunotherapy was not performed. Although the relationship between @entity792 and @entity73 in this @entity1 was unclear, the present observations suggest the coexistence of @entity179 and @entity792 as the underlying pathogenic mechanism. (Received March 3, 2014; Accepted February 17, 2015; Published July 1, 2015).
