QRS interval in tricyclic antidepressant overdosage: inaccuracy as a XXXX indicator in emergency settings.

@entity1 @entity410 @entity137 @entity2974 @entity2613 @entity943 @entity1445
Emergency department treatment and disposition of tricyclic antidepressant ( @entity2974 )- @entity1445 @entity1 remains a common and difficult problem. Various clinical findings have been proposed as @entity137 indicators. To study the performance of QRS duration as a predictor of @entity137 in our @entity1 population, we retrospectively reviewed the cases of all @entity1 presenting to our @entity2613 with @entity2974 overdosage. The charts of 102 @entity1 with quantitative or qualitative laboratory confirmation of @entity2974 ingestion were reviewed for @entity2613 findings and hospital course with specific attention to the occurrence of @entity943 ( @entity943 ) or @entity410 . The @entity2613 ECG revealed that 57 @entity1 had a maximal 12-lead ECG QRS interval duration (QRS) of less than .10 seconds (Group 1). The remaining 45 @entity1 had QRS greater than or equal to .10 seconds (Group 2). Three @entity1 (5%) in Group 1 and three (6%) in Group 2 experienced @entity943 . Four @entity1 (7%) in Group 1 and five (11%) in Group 2 experienced @entity410 . There was no significant difference in the rate of occurrence of @entity943 or @entity410 between the two groups. Of note was the fact that five of eight @entity943 and nine of 11 @entity410 occurred in the @entity2613 setting. We conclude that determination of QRS duration is not an accurate indicator of VA or @entity410 risk for all @entity2974 - @entity1445 populations. In particular, risk of toxic events during the emergency phase of @entity2974 @entity1445 does not appear to be indicated by evaluation of the QRS duration in the @entity2613 .
