The oculomotor behaviour of XXXX albinos.

@entity1 @entity346 @entity1319
@entity1319 were recorded in 16 @entity1 albinos with a scleral search coil technique. Spontaneous @entity346 , responses to target steps, voluntary pursuit and @entity346 ( @entity346 ) were assessed, including the effects of selective stimulation of the nasal or temporal halves of the retina. The results suggest a subdivision of albinos into three classes of oculomotor behaviour. Class I (n = 11) is characterized by @entity346 (of the pendular unidirectional jerk or bidirectional jerk type), the absence of true horizontal @entity346 but the presence of the ability to control the direction of gaze in an imprecise way. In Class II (n = 2) there is a vigorous unidirectional jerk @entity346 which reverses in direction spontaneously or as a result of visual stimulation. Moving stimuli typically elicited inverted pursuit, the smooth @entity1319 having a direction opposite to that of the stimulus movement. Class III (n = 3) is characterized by very little or no spontaneous @entity346 and virtually normal oculomotor responses. Only pursuit of motion in the temporal direction, projected onto the temporal half retina, was defective. In all three classes, vertical @entity1319 were disturbed much less than horizontal. Anomalous visual projections (confirmed in all subjects by asymmetrical monocular visual evoked cortical potentials) are a likely basic cause underlying the oculomotor instability, but the large intersubject differences show that the eventual consequences of misrouting and secondary adaptations can vary widely among subjects.
