Replacement of antipsychotic and antiepileptic medication by XXXX in a @entity1 with @entity2418 .

@entity1 @entity410 @entity1833 @entity716 @entity302 @entity2922 @entity2418 @entity38171
We report the case of a 23-year-old @entity1 with @entity2418 ( @entity2418 ) and a history of @entity716 and @entity410 . She had been treated with conventional antipsychotic and antiepileptic drugs for 10 and 3 years, respectively. However, she continued to experience occasional @entity1833 and paroxysmal jerking of the extremities. @entity38171 500 mg b.i.d. (later reduced to 250 mg t.i.d.) was added to her regimen. @entity1833 and @entity410 stopped shortly. Over the course of approximately 1 year, the previous medications were discontinued without recurrence of @entity716 and @entity302 symptoms. Eventually, improved mental functions and behaviour enabled her transition from living in a licensed residential facility to sharing a private residence with a partner. @entity2418 is associated with haploinsufficiency of @entity2922 -methyltransferase, leading to excessive extraneuronal @entity2922 concentrations. Alpha-Methyldopa inhibits @entity2922 neurotransmission in a variety of ways. It is possible that the drug compensated for genetically disturbed @entity2922 transmission thus achieving beneficial effects in this case.
