XXXX in childhood: correlation between nailfold capillaroscopy findings and clinical and laboratory data.

@entity1 @entity6017 @entity627 @entity5442 @entity3928 @entity2631 @entity425 @entity8817 @entity272
OBJECTIVE: Nailfold capillaroscopy is an important tool for the diagnosis and follow-up of @entity1 with @entity627 , in particular @entity6017 and @entity2631 . A relationship has been observed in adults between improved capillaroscopic findings and reduced disease activity. Our aim was to correlate disease activity (clinical and laboratory data) and nailfold capillaroscopy findings in 18 @entity1 with @entity5442 . METHODS: This prospective study included 13 @entity8817 @entity1 (Bohan and Peter criteria) (mean age of 8.8 years) and five @entity1 with @entity3928 (mean age of 15.7 years). We evaluated disease activity ( @entity272 and @entity425 , muscle enzymes and acute phase reactants) and its correlation with nailfold capillaroscopy findings (dilatation of isolated loops, dropout of surrounding vessels and giant capillary loops). We used a microscope with special light and magnification of 10 to 16X. RESULTS: Eighteen @entity1 underwent a total of 26 capillaroscopic examinations, seven of them on two or more occasions (13 were performed during the active disease phase and 13 during remission). Twelve of the 13 examinations performed during the active phase exhibited @entity2631 pattern and 8 of the 13 examinations performed during remission were normal. Therefore, in 20 of the 26 examinations clinical and laboratory data and nailfold capillaroscopy findings correlated (p = 0.01). CONCLUSIONS: Nailfold capillaroscopy is a non-invasive examination that offers satisfactory correlation with disease activity and could be a useful tool for the diagnosis and follow-up of @entity5442 .
