Role of compression modalities in a prophylactic program for XXXX .

@entity1 @entity548 @entity3179 @entity1151 @entity1150 @entity1031 @entity715 @entity1211 @entity291 @entity11942
During the past decade, we have learned a great deal about the etiology, pathogenesis, diagnosis, and treatment of @entity1031 . Subcutaneous heparin has emerged as a major deterrent worldwide for @entity715 prevention but is associated with the potential risk of @entity548 and cannot be used in certain @entity1 situations. External compression modalities have emerged as major alternate forms of prophylaxis. We have learned that these devices stimulate the fibrinolytic system, prevent @entity3179 and the endothelial injury that can accompany extreme @entity1211 . Since they are not associated with @entity548 or other serious complications, they are attractive methods for most surgeons, including those performing delicate or complex surgical procedures. Independent studies worldwide have demonstrated their effectiveness in reducing @entity1150 , as recognized by the NIH Consensus Development Panel, and the evidence is compelling that @entity11942 efficacy is a valid marker for PE efficacy. Since these devices reduce the incidence of @entity1150 , they almost certainly must prevent @entity1151 ; however, a properly designed protocol should be conducted to validate these assumptions. Evidence suggests that full-leg sequential compression is superior to @entity291 compression, but further study is necessary. We believe that a hospital-wide plan, including risk-factor assessment and application of clinical management guidelines, including all available modalities, is important to provide the maximum protection of @entity1 with the lowest risk of side effects. Such a program has been very successful in our community.
