Effective Downsizing of a Large Oesophageal Gastrointestinal Stromal @entity5 with Neoadjuvant XXXX Enabling an Uncomplicated and without @entity5 Rupture Laparoscopic-Assisted Ivor-Lewis Oesophagectomy.

@entity1 @entity677 @entity5 @entity397 @entity1282 @entity2213
Neoadjuvant @entity2213 for @entity5 ( @entity5 ) is increasingly used nowadays. As oesophagectomy is associated with high morbidity and mortality, a preoperative downsizing of an oesophageal @entity677 to limit the extent of resection would be ideal. Because these @entity5 are rare and neoadjuvant treatment with @entity2213 is recent, there is limited literature available regarding neoadjuvant administration of @entity2213 in @entity1 with oesophageal @entity5 . A 50-year-old @entity1 presented with total @entity1282 . An upper endoscopy and biopsy revealed a large submucosal KIT-positive @entity677 obstructing the mid oesophagus. CT confirmed a lesion measuring 99   mm * 50   mm * 104   mm. Because the size and location of the @entity5 increased the risk of intraoperative @entity397 , it was decided to administer preoperative @entity2213 . The @entity1 had an excellent clinical and radiological response. Her @entity1282 gradually resolved and the follow-up CT scans of the first 10 months showed a gradually reducing @entity5 size to 54   mm * 33   mm * 42   mm. The @entity1 underwent an uneventful laparoscopic-assisted Ivor-Lewis oesophagectomy. Postoperatively, the @entity1 continued with adjuvant @entity2213 . At the last follow-up, 1 year from operation and 38 months from the diagnosis, the @entity1 is disease free.
