Self-reported sleep duration is associated with reduced glomerular filtration rate among adults with XXXX : a population-based study from rural northeast China.

@entity1 @entity644 @entity308 @entity101 @entity740
UNASSIGNED: Short sleep duration has been found recently to be a predictor of @entity644 . However, population-based investigations addressing the association between self-reported sleep duration and glomerular filtration rate (GFR) among @entity101 @entity1 are lacking. We therefore sought to investigate the extent to which self-reported sleep duration might be associated with reduced GFR in a large @entity101 population in rural northeast China. A total of 5555 @entity101 @entity1 , aged >= 35  years, in rural areas of Liaoning Province, China, were screened between January 2012 and August 2013, using a stratified, cluster multi-stage sampling scheme. Anthropometric measurements, self-reported sleep duration, blood biochemical indexes and other health-related variables were collected by medically trained personnel. Reduced GFR was defined as the estimated GFR (eGFR)  <  60  mL  min(-1)   1.73  m(2) . On average, @entity1 slept for 6.9      1.6  h per night. Mean self-reported sleep duration decreased with eGFR (P  <  0.001). For both genders, a lower prevalence of reduced GFR was observed among @entity1 who slept  <=6  h per night in total. In the multivariable regression model, after adjustments for age, gender, ethnicity, lifestyle factors, clinical correlates, @entity308 and general quality of life, @entity1 who slept for 6  h or less per night were associated with a higher risk of reduced GFR [odds ratio (OR: 1.70, 95% confidence interval (CI): 1.05-2.73] compared with the reference group (self-reported sleep duration >7 and  <=8  h  day(-1) ). We concluded that short self-reported sleep duration ( <=6  h per night) was related significantly to an increased risk of reduced GFR in a @entity101 population. This novel risk factor should be taken into consideration during daily management of @entity101 to prevent @entity740 .
