Studies of @entity5163 in Central America. VII. Treatment of preschool @entity1 with XXXX and @entity29406 under field conditions in a Guatemalan highland village.

@entity1 @entity697 @entity11682 @entity5163 @entity17998 @entity29406 @entity526
2 antimicrobial agents, @entity17998 , an antibiotic, and a @entity11682 , @entity29406 , were tested as supplement therapeutic treatment together with rehydration and nursing care in 535 cases of @entity697 in a Guatemalan highland village. All cases were under 5 years of age. 417 cases were bacteriologically tested, and 18% suffered from a recognized bacterial pathogen (Shigella or @entity526 ) and 82% were not. Cases occurred in 2 villages in the period from October 1960-December 1961. In 1 village, @entity1 were treated with the antimicrobial agents in addition to general medical care; in the other, cases were treated with family nursing and folk remedies only. The general death rate from all causes was lower in the village where general medical care was provided. Deaths from @entity697 were relatively few in both villages. An annual mortality from @entity5163 of 7.7 per 1000 @entity1 in the treated community and of 17.3 in the untreated community was reported. The difference, however, was attributed mostly to general supportive measure, especially rehydration and nursing care. In vitro, @entity17998 was very effective, but it did not prove so clinically. The @entity11682 was effective against only 61% of Shigella strains in vitro, and the clinical result was somewhat less.
