XXXX after ingestion or inhalation of cereals involves similar allergens in different ages.

@entity748 @entity1 @entity2247 @entity353 @entity66 @entity5419 @entity566 @entity294 @entity391 @entity8060 @entity56 @entity5369 @entity3505 @entity484
BACKGROUND: Cereals are among the major foods that account for @entity56 reactions. Salt-soluble proteins appear to be the most important allergens contributing to the @entity748 response. In contrast, very limited information is available regarding cereal allergens responsible for @entity56 after ingestion of cereal proteins. OBJECTIVE: The aim of this study was to evaluate the allergenic reactivity of ingested and inhaled cereal allergens in different ages, in order to investigate if the response to different allergens would depend on the sensitization route. METHODS: We included 66 @entity1 in three groups. Group 1: 40 @entity1 aged 3 to 6 months who suffered from @entity294 , @entity391 , @entity484 or @entity353 after the introduction of cereal formula in their diet and in which a possibility of @entity66 was discarded. Group 2: 18 adults with @entity5419 due to cereals tested by prick tests, specific IgE and food challenge. Group 3: eight @entity1 previously diagnosed as having @entity8060 . Sera pool samples were collected from each group of @entity1 and IgE immunoblotting was performed. RESULTS: We found an important sensitization to cereal in the 40 @entity1 . The most important allergens were @entity3505 followed by @entity2247 and rye. Among the adults with @entity566 , sensitization to other allergens was common, especially to @entity5369 (rye grass) pollen. Immunoblotting showed similar allergenic detection in the three groups. CONCLUSION: Clinically significant reactivity to cereal may be observed in early life. Inhalation and ingestion routes causing @entity566 seem to involve similar allergens. The diet control was more effective in @entity1 . The possibility of @entity566 after the introduction of cereal formula during the lactation period should not be underestimated.
