[Assessment of hemodynamics of XXXX with dynamic MR imaging].

@entity5 @entity1 @entity1653 @entity7241
Dynamic MR imaging provides hemodynamic information about normal and pathologic tissue of the brain. The purpose of our study was to evaluate the usefulness of dynamic MR imaging in the assessment of @entity5 vascularity and the @entity5 tissue blood flow of @entity1653 . We studied 13 @entity1 with @entity1653 using dynamic spin-echo MR imaging. The histological subtypes of @entity1653 were confirmed by the examination of surgical specimens in all @entity1 , and @entity5 were meningothelial in 9 cases, fibrous in 2, transitional in 1, and psammomatous in 1. Serial images were obtained every 18-24 sec for 8 minutes and 30 seconds after rapid injection of @entity7241 . Different parameters (time to peak, maximum of signal intensity and the washout ratio) were calculated directly from signal intensity curves. As an indicator of @entity5 vascularity, microvessel density was counted based on immunohistochemically stained sections and @entity5 tissue blood flow was measured using an xenon-CT system. The maximum of signal intensity corresponded to the @entity5 vascularity. With dynamic MR imaging, the time intensity curves (TI curves) were divided into two patterns; type 1 had a steep increase with a peak and type 2 had a slow increase to a peak followed by plateau. The maximum of signal intensity measured from TI curve of dynamic MR imaging correlated significantly with microvessel density (R2 = 0.840, p < 0.0001). Linear regression revealed a significant positive relation between the washout ratio and the @entity5 tissue blood flow in group showed type 1 on TI curve (R2 = 0.961, p < 0.001). There was also a significant negative correlation between the time to peak and the @entity5 tissue blood flow (R2 = 0.792, p < 0.01). We suggest that dynamic MR imaging is useful for evaluating hemodynamics of @entity1653 .
