Time course of XXXX .

@entity296 @entity63 @entity235 @entity4 @entity1563 @entity26 @entity1188 @entity741
The time course of @entity741 was studied in @entity235 myocardium by electron microscopy. @entity63 of the myocardium produces ultrastructural alterations of mitochondria, nuclei, contractile apparatus, and the SR- and T-tubular system that are accompanied by loss of glycogen and intracellular @entity4 . These changes are more pronounced with increasing severity of @entity63 , and they allow the differentiation between different stages of reversible and of irreversible injury. Reperfusion of reversibly injured tissue leads to structural recovery; reperfusion of irreversibly injured tissue produces further deterioration. On the basis of ultrastructural data, it was found that in a @entity235 , after 45 minutes of @entity1563 , @entity1188 was present in 20% of all animals. Transmural @entity1188 was present in 24% of all @entity235 after 90 minutes of @entity1563 and in 53% after 24 hours. The individual variability in the speed of development of @entity1188 is caused by the rate of @entity26 consumption at the time of occlusion and by the amount of collateral flow. Intermittent @entity63 is much better tolerated than permanent @entity63 of the same duration. Species differences are evident. The course of development of @entity296 , therefore, depends on time, rate of @entity26 consumption, collateral flow, mode of @entity63 , and on the species investigated.
