XXXX in adults with @entity302 : The relationship between subjective and objective assessments of cognition.

@entity1 @entity308 @entity73 @entity148 @entity302 @entity2414
AIM: This study aimed to assess the relationship between objective measures of cognition and subjective perception of cognitive functioning reported by @entity1 with @entity302 and their caregivers. METHODS: One hundred @entity1 with @entity302 attending hospital neurology outpatient clinics and their caregivers were enrolled in this study. The EpiTrack   (version 1) brief cognitive screening tool was used to measure objective impairment, the ABNAS questionnaire (A-B Neuropsychological Assessment Schedule) to assess subjective cognitive performance, and a version of the ABNAS designed to be completed by caregivers (C-ABNAS) to document caregivers' views. @entity1 @entity148 and @entity308 were measured using the Hospital Anxiety and @entity308 Scale (HADS) and considered as covariates. @entity1 with an uncertain diagnosis of @entity302 or likely severe comorbid mood or @entity148 were excluded. RESULTS: Data from 82 @entity1 were analyzed after exclusion of @entity1 with uncertain diagnoses or likely severe comorbid mood or @entity148 . Fifty-nine (72%) had a degree of objective @entity73 . Fifty (84.7%) of these 59 @entity1 had 'high' ABNAS scores concordant with the objective assessment, and 43 (72.9%) had high C-ABNAS scores matching the abnormalities detected by objective screening. Of the 23 (28%) @entity1 without objective @entity73 , seven (30.4%) had concordantly low ABNAS scores, and 10 (43.4%) had concordantly low C-ABNAS scores. @entity1 @entity2414 was more often reported by @entity1 themselves than by caregivers (p=0.011). Carers were significantly more likely to rate @entity1 as having impaired motor coordination than @entity1 themselves. A small part of the variance of the EpiTrack score was predicted by the C-ABNAS. Objective cognitive performance did not predict ABNAS or C-ABNAS scores. CONCLUSIONS: Self-report or caregiver report questionnaires identify @entity1 with @entity302 and objective @entity73 more accurately than @entity1 with intact cognition. Those without objective evidence of @entity73 may, nevertheless, perceive themselves as having @entity2414 ; it is these @entity1 , therefore, who most require both subjective and objective assessments of cognition, including carers' assessments, in order to establish the nature of their symptoms. None of these assessment measures can be used as a reliable proxy for another, each contributes individually to a comprehensive assessment of cognition, and all must be used in conjunction with measures of mood and @entity148 .
