New subgrouping of small XXXX .

@entity1 @entity1377 @entity5 @entity189 @entity3 @entity259
Clinicopathologic findings on small @entity259 measuring 10 mm or less in diameter were analyzed in 78 thyroidectomied cases. The authors divided small @entity259 into two subgroups according to diameter: 0 less than or equal to 5 mm (classified as minute @entity189 ) and 5 less than 0 less than or equal to 10 mm (classified as tiny @entity189 ). Characteristics including sex, age, histologic type, extrathyroid invasion, and lymph node @entity3 were examined in each subgroup. In @entity1 with minute @entity189 , very few incidences of extrathyroid invasion and lymph node @entity3 were found. However, these involvements, especially lymph node @entity3 , were found more frequently in @entity1 with tiny @entity189 . The incidence of cervical lymph node @entity3 was 13% in minute @entity189 and 59% in tiny @entity189 . (P less than 0.01). These findings suggest the need for more careful observation and treatment of tiny @entity189 , especially with respect to lymph node @entity3 . In accordance with World Health Organization (WHO) classification, the histologic types of @entity259 were classified into @entity1377 . The @entity1377 and @entity189 ratios were compared between the two subgroups. The discovery rate of @entity189 was significantly higher in minute @entity189 than in tiny @entity189 (P less than 0.005). This suggests that the @entity189 ratio (p/f) increases as the size of the @entity189 increases, and that @entity189 is the "seed," or initial form, of @entity259 . The female-male ratio in small @entity259 suggests that there is no sex difference in carcinogenesis but that there is more probability for @entity5 development in the thyroid in @entity1 .
