Risk factors for survival and local recurrence after particle radiotherapy for XXXX .

@entity5 @entity157 @entity1
BACKGROUND: Particle radiotherapy is a novel treatment for @entity5 . The present study aimed to evaluate risk factors for overall survival and local control after particle radiotherapy of @entity157 ( @entity157 ), and to identify suitable candidates for this treatment. METHODS: All @entity1 with a single @entity157 smaller than 5 cm in diameter treated by particle radiotherapy between 2001 and 2008 were identified retrospectively from a prospectively collected database. Clinical outcomes and prognostic factors were analysed. RESULTS: A total of 150 @entity1 were included. Five-year overall survival and local control rates were 50.9 and 92.3 per cent respectively. Multivariable analysis revealed that several factors, including age and @entity1 -Pugh classification, significantly influenced overall survival. Proximity to the digestive tract and @entity1 -Pugh classification were independent risk factors for local recurrence. Other @entity5 factors including size, gross classification, previous treatment, macroscopic vascular invasion, and @entity5 location in relation to the diaphragm and large vessels did not influence local control rate. CONCLUSION: Particle radiotherapy seems safe and effective, and may be a novel treatment for small @entity157 . Recurrences are more frequent when the @entity5 is located close to the gut.
