Dual platelet inhibition in cases of severe XXXX following retrobulbar and peribulbar anesthesia.

@entity1 @entity1410 @entity548
PURPOSE: To evaluate the prevalence of dual platelet inhibition in cases of severe @entity548 following retrobulbar and peribulbar anesthesia. SETTING: Department of Ophthalmology, Ludwig-Maximilans Universit  t, M  nchen, Germany. DESIGN: Retrospective study. METHODS: Two groups of @entity1 were screened retrospectively over a 5-year period for the inclusion criterion of severe @entity1410 after retrobulbar or parabulbar injection. The first group consisted of emergency cases referred to the clinic. A second group of @entity1 had received retrobulbar block at the hospital. All cases were collected and screened for the presence of antiplatelet therapy. RESULTS: Among roughly 160   000 @entity1 records screened, 3 @entity1 with grade @entity1410 were identified. Two of these @entity1 were taking dual antiplatelet medications and 2 were on anticoagulation therapy during the time of retrobulbar or peribulbar anesthesia. None of the cases showed single medication platelet inhibition. The visual acuity of all @entity1 stayed low at the 6-month follow-up (1.2 logMAR in 1 @entity1 and no light perception in 2 @entity1 ). CONCLUSIONS: Retrobulbar @entity1410 is a rare but severe complication of retrobulbar anesthesia. With the high prevalence of dual platelet inhibition found in these cases, a prospective controlled trial seems unethical. In these high-risk @entity1 , surgery should be performed under topical anesthesia if possible or general anesthesia if necessary. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
