Progressive, @entity410 -Like, Spike-Wave Discharges Are Common in Both Injured and Uninjured XXXX : Implications for the Fluid Percussion Injury Model of @entity32933 .

@entity131 @entity410 @entity146 @entity11228 @entity2048 @entity13974 @entity6191 @entity35 @entity32933
@entity13974 and repetitive, high-voltage spikes have been recorded in the electrocorticogram (ECoG) of @entity35 weeks and months after fluid percussion injury (FPI), a model of @entity131 . These ECoG events, which have many similarities to @entity11228 ( @entity11228 ) and @entity2048 , have been proposed to represent @entity6191 @entity410 characteristic of @entity32933 ( @entity32933 ). The present study quantified features of SWD episodes in @entity35 at different time points after moderate to severe FPI, and compared them with age-matched control @entity35 . Control and FPI-injured @entity35 at 1 year of age displayed large-amplitude and frequent SWD events at frontal and parietal recording sites. At 3-6 months, @entity11228 were shorter in duration and less frequent; extremely brief @entity11228 (i.e., "larval") were detected as early as 1 month. The onset of the @entity11228 was nearly always synchronous across electrodes and of larger amplitude in frontal regions. A sensory stimulus, such as a click, immediately and consistently stopped the occurrence of the @entity11228 . @entity11228 were consistently accompanied by @entity146 . All features of @entity11228 in control and experimental (FPI) @entity35 were indistinguishable. None of the FPI-treated @entity35 developed @entity6191 or convulsive @entity410 that could be distinguished electrographically or behaviorally from @entity11228 . Because @entity11228 have features similar to genetic @entity2048 , these results challenge the hypothesis that @entity11228 after FPI reflect @entity32933 .
