Treatment preferences in recurrent XXXX .

@entity43 @entity1 @entity5
OBJECTIVES: In the case of recurrent @entity43 , salvage therapy represents the potential to trade off between quality and quantity of life. @entity1 and physician face a choice between chemotherapy directed at slowing disease progression and supportive or palliative care that focuses on symptom management. To date, no studies have investigated the effects of best supportive care on @entity43 @entity1 ' quality of life and length of life as compared to salvage therapy. In other @entity5 , both quantity and quality of life considerations have been shown to affect treatment preferences. METHODS: Using a decision board, we assessed preferences for salvage therapy or palliative care in the case of recurrent @entity43 among 81 @entity43 @entity1 receiving first-line chemotherapy and 75 Noncancer Controls. RESULTS: Compared to Noncancer Controls, @entity43 @entity1 overwhelmingly preferred salvage therapy; quantity of life was of primary importance. In both groups, preference was not related to age, marital status, number of @entity1 , or employment status. On average, @entity1 indicated they would switch from salvage therapy to palliative care when the median survival associated with salvage therapy was reduced to 5 months. Noncancer Controls would switch significantly sooner, when the median increment in survival period was reduced to 8 months. Switchpoint was not associated with life satisfaction, quality of life, or psychological or spiritual well-being in either group. CONCLUSIONS: The majority of @entity1 , independent of a @entity5 diagnosis, indicated a desire for continuing aggressive treatment, despite poor outcomes. Quality of life was of secondary importance, especially among @entity43 @entity1 .
