XXXX Is Involved in the @entity1255 -Induced Apoptosis in @entity1 Coronary Artery Endothelial Cells by Regulating the Expression of @entity522 .

@entity1 @entity64 @entity522 @entity101 @entity301 @entity1255 @entity5784 @entity65 @entity39767
@entity1255 ( @entity5784 ) is an independent risk factor for a variety of @entity65 , such as @entity301 , @entity101 , @entity64 , etc. There is a close relationship between the vascular endothelial cell apoptosis and these diseases. Recent studies have shown @entity1255 can induce apoptosis in endothelial cells, which may be an important mechanism for the development of theses @entity65 . Although there are several reports about how the @entity5784 induces apoptosis in endothelial cells, the exact mechanism is not fully understood. MicroRNAs are small, non-coding RNA. Previous studies have shown that there is a close relationship between several microRNAs and cell apoptosis. However, there are no studies about the role of microRNAs in @entity5784 -induced apoptosis in endothelial cells so far. In this study, we constructed the model of @entity1255 -induced apoptosis in @entity1 coronary artery endothelial cells (HCAECs) and found @entity39767 was significantly down-regulated by 1 mmol/L @entity5784 . In addition, overexpression of @entity39767 can improve the @entity5784 -induced apoptosis in HCAECs by downregulating @entity522 expression. Therefore, @entity39767 may play an important role in @entity5784 -induced apoptosis in endothelial cells.
