Risk factors for late cervical lymph node XXXX in @entity1 with stage I or II @entity5772 .

@entity1 @entity5 @entity957 @entity1600 @entity3 @entity5772
BACKGROUND: Many histopathologic parameters in @entity957 have been identified as predictive factors for cervical lymph @entity3 . However, predictive factors for occult cervical lymph node @entity3 and the criterion for elective therapy remain inconclusive. This study analyzed the clinicopathologic factors associated with late cervical lymph node @entity3 in @entity1 with @entity5772 . METHODS: The clinicopathologic features of 50 consecutive @entity1 seen between January 1985-December 1996 with previously untreated stage I or II @entity957 were reviewed. All @entity1 were treated with partial glossectomy without elective neck dissection. Their mean age was 54.5 y (range, 23-90 y) and the male-female ratio was 1.2:1 (27 @entity1 and 23 @entity1 ); 30 cases were stage I, and 20 cases were stage II. Clinicopathologic factors were analyzed to determine factors predicting late cervical @entity1600 . RESULTS: The overall cervical @entity1600 rate was 14.0% (7 of 50). Clinicopathologic factors significantly associated with the development of cervical @entity1600 were @entity5 size (> or =30 mm), @entity5 depth (> or =4 mm), differentiation, mode of invasion, microvascular invasion, and histologic grade of @entity5 . In a multivariate logistic regression analysis, moderately differentiated @entity957 with @entity5 depth > or =4 mm had predictive value for late cervical @entity1600 and diminished overall survival (odds ratio, 10.0; p =.02; hazards ratio, 7.0; p =.039). CONCLUSIONS: The findings of this study demonstrate @entity5 depth > or =4 mm moderately differentiated @entity957 have a substantially higher rate of late cervical @entity3 . In the basis of these data, it is our recommendation that this be used in the decision to electively treat the neck.
