[Epidemiology of XXXX in Veszpr  m county of Western Hungary between 1977 and 2001].

@entity1 @entity9916 @entity4272 @entity31 @entity29 @entity1960 @entity204 @entity30
INTRODUCTION: An epidemiological study of @entity29 ( @entity29 ) in Veszpr  m county (located in western part of Hungary) was carried out from 1977 to 2001. METHODS: Both hospital and outpatient records of @entity29 @entity1 were collected reviewed carefully. Most @entity1 have been followed up regularly. RESULTS: The number of population has decreased during the observed period from 386,000 to 376,000. The county has both industrial and agrarian parts. 560 new @entity31 ( @entity31 ) cases, 212 @entity30 ( @entity30 ), and 40 indeterminate colitides (IC) were diagnosed in the investigated period. Incidence rate increased from 1.66 (1977-1981) to 11.01 (1997-2001) in @entity31 , and from 0.41 to 4.68 in @entity30 , respectively. The incidence rate in IC rose from 0.26 to 0.74. The M/F ratio in @entity31 was 1.06, in @entity30 : 1.03, respectively, 41 UD @entity1 and 13 @entity30 @entity1 died, the cause of @entity204 was disease related in 6 @entity31 and in 6 @entity30 @entity1 . The average age at @entity204 in @entity31 was not different from that observed in general population (66.4 years) but in @entity30 (50.1 years) it was much earlier. The disease related mortality was low, 0.06/100,000 both in @entity31 and @entity30 . The prevalence rate at the end of 2001 was 142.6 for @entity31 and 52.9/100,000 inhabitants for @entity30 . Mean age at onset in @entity31 was 38.9 +/- 15.5 years, in @entity30 31.7 +/- 12.8 years. We observed only one peak onset of the diseases, in @entity31 it was between 30 and 40 years, in @entity30 between 20 and 30 years. @entity1 living in towns were more liable to acquire the disease (ORUC = 1.27, ORCD = 1.13). The rate of smokers at the onset was 14.3% (OR = 0.25) in @entity31 and 50.5% (OR = 1.98) in @entity30 . Ex-smokers were 18.4% and 6.4%. Family history of @entity29 was present in 3.4% in @entity31 and 9.9% in @entity30 . The location of @entity31 (according to the known largest extent) was @entity4272 in 112 cases, @entity9916 in 162 cases, @entity1960 in 117 and subtotal or pancolitis in 169 cases. The location of @entity30 was only ileal in 68 cases, ileocolonic in 87 cases, colonic in 57 cases. The behaviour of @entity30 was non-stricturing-non-penetrating in 63 cases, stricturing in 54 cases, penetrating in 95 cases. 59.4% of the @entity30 @entity1 had at least one operation, 6.1% had more than 3 operations. CONCLUSION: The incidence and prevalence rates have increased steadily in Veszpr  m County, now it reaches that of most western European countries. There were no gender differences either in @entity31 or @entity30 . Smoking seemed to be a risk factor for @entity30 , but it was preventive for @entity31 . The rapid increase in incidence supports a role for environmental (e.g. diet, lifestyle changes) risk factors.
