Bone level variation after vertical ridge augmentation: resorbable barriers versus XXXX -reinforced barriers. A 6-year double-blind randomized clinical trial.

@entity1 @entity702 @entity736
PURPOSE: To compare the efficacy of two different techniques for vertical bone regeneration at implant placement with particulate autogenous bone at 6 years after loading by means of a double-blind, superiority, parallel-group randomized clinical trial. MATERIALS AND METHODS: The study was conducted in a private center in Italy between April 2004 and December 2011. @entity1 in whom vertical bone augmentation was indicated in combination with the placement of single or multiple implants were eligible for inclusion in this trial. @entity1 were randomized to receive either resorbable collagen barriers supported by an osteosynthesis plate (test group) or nonresorbable @entity702 -reinforced expanded @entity736 barriers (control group). The outcome variables-radiographic bone variation at implant sites, implant failures, and complications- were evaluated 6 years after loading. Randomization was done by computer, with allocation concealed by opaque sequentially numbered sealed envelopes. The @entity1 and the radiographic examiner were blinded to group assignment. RESULTS: Twenty-two @entity1 were randomized: 11 to the resorbable barrier group and 11 to the nonresorbable (control) group. One control group @entity1 dropped out. The mean bone level 6 years after surgery was 1.33 mm for the resorbable group and 1.00 mm for the nonresorbable group. The adjusted difference in bone changes between groups was 0.15 mm (95% confidence interval, -0.39 to 0.69, P = .5713). No implant failures or complications occurred after loading. CONCLUSION: No differences were observed in this comparison of resorbable and nonresorbable barriers with simultaneous implant placement for vertical ridge augmentation.
