XXXX -related lesion characteristics in @entity1 with stable or @entity1459 . A study with intracoronary angioscopy and ultrasound.

@entity1 @entity1187 @entity5892 @entity731 @entity63 @entity75 @entity5749 @entity1459 @entity397 @entity715
BACKGROUND: Postmortem-derived findings support the common beliefs that lipid-rich coronary plaques with a thin, fibrous cap are prone to @entity397 and that @entity397 and superimposed @entity715 are the primary mechanisms causing @entity1187 . In vivo imaging with intracoronary techniques may disclose differences in the characterization of @entity731 in @entity1 with stable or @entity1459 and thus may provide clues to which plaques may @entity397 and whether @entity397 and @entity715 are active. METHODS AND RESULTS: We assessed the characteristics of the @entity63 -related lesions with coronary angiography and intracoronary angioscopy and determined their compositions with intracoronary ultrasound in 44 @entity1 with unstable and 23 @entity1 with @entity5749 . The angiographic images were classified as noncomplex (smooth borders) or complex (irregular borders, @entity75 , @entity715 ). Angioscopic images were classified as either stable (smooth surface) or @entity715 (red @entity715 ). The ultrasound characteristics of the lesion were classified as poorly echo-reflective, highly echo-reflective with shadowing, or highly echo-reflective without shadowing. There was a poor correlation between clinical status and angiographic findings. An @entity75 (n = 33) was concordant with @entity1459 in 55% (24 of 44); a noncomplex lesion (n = 34) was concordant with @entity5749 in 61% (14 of 23). There was a good correlation between clinical status and angioscopic findings. An angioscopic @entity5892 (n = 34) was concordant with @entity1459 in 68% (30 of 44); a stable lesion (n = 33) was concordant with @entity5749 in 83% (19 of 23). The ultrasound-obtained composition of the plaque was similar in @entity1 with unstable and @entity5749 . CONCLUSIONS: Angiography discriminates poorly between lesions in stable and @entity1459 . Angioscopy demonstrated that @entity397 and @entity715 were present in 17% of @entity5749 and 68% of @entity1459 @entity1 . Currently available ultrasound technology does not discriminate stable from unstable plaques.
