Real-time sonoelastography in the diagnosis of XXXX .

@entity1 @entity5664 @entity263
AIMS: Sonoelastography (SEG) is a noninvasive ultrasound (US) method able to differentiate tissues according to their stiffness. Our objective was to establish whether transrectal (TR) SEG may improve @entity263 detection, alone or associated with other US methods. @entity1 AND METHODS: We analyzed the data of 65 @entity1 , mean age 68 years (49 - 81 years), examined March 2009-September 2010. The @entity1 had at least one of the following malignancy suspicion criteria: PSA > 4 ng /ml (minimum 2 determinations), nodule(s) at digital rectal examination (DRE +) or previous gray scale TRUS positive appearance. All @entity1 underwent TRUS, Doppler-US and SEG in the same session, followed by systematic prostate biopsies (6-12 cores). Histopathology and imaging findings were correlated. RESULTS: Twenty-eight out of 65 @entity1 (43%) were diagnosed with @entity263 . Overall, SEG had a sensitivity of 67.85%, specificity 62.16%, positive predictive value 57.57% and negative predictive value 71.85%. However, SEG diagnostic reliability appeared to be higher for subgroups of @entity1 having PSA >10 ng / ml, lower number of fragments collected by @entity5664 (6 vs. 10-12 cores) and age > 70 years. CONCLUSION: SEG appears to be useful in the diagnosis of @entity263 as it may increase the diagnosis accuracy in specific target groups.
