Expression of the @entity56905 molecule in benign and malignant XXXX @entity5 .

@entity1313 @entity235 @entity5 @entity5072 @entity56905 @entity1373 @entity189 @entity4383 @entity652 @entity1319
Claudins are integral membrane proteins of the tight junction structures expressed by epithelial and endothelial cells. The present study has evaluated the expression of @entity56905 in 10 normal @entity235 hepatoid glands and in 67 hepatoid glands with @entity5072 and @entity1313 . The lesions studied included normal hepatoid glands (n = 10), @entity4383 (n = 10), @entity652 (n = 12), @entity189 (n = 15), @entity189 (n = 15) and @entity189 (n = 15). There was an intensive expression of @entity56905 in normal @entity235 hepatoid glands as well as in @entity1373 and @entity652 . @entity56905 was detected as a well-localised linear circumferential membranous staining pattern of epithelial cells (mature hepatoid cells) in normal hepatoid glands, @entity1373 and @entity652 . In @entity4383 and @entity652 , the reserve cells showed membrane positivity for the @entity56905 molecule. There was a weaker expression in @entity189 . In the @entity189 , the basaloid reserve cells never expressed the @entity56905 molecule. The multiple small parts of @entity189 in which the cells exhibited typical hepatoid features showed a well-localised linear circumferential membranous staining pattern for @entity56905 . The numerical score for cellular expression of @entity56905 was higher in @entity189 than in @entity189 , but moderately lower than in @entity652 . The anaplastic, poorly differentiated @entity189 showed an overexpression of @entity56905 . These results suggest that low @entity56905 expression in @entity189 is a molecular characteristic indicative of increasing cellular disorientation, @entity1319 and invasion by @entity5 cells, and @entity56905 seems to be helpful in distinguishing @entity189 from @entity189 and @entity189 of the hepatoid gland. In addition, @entity56905 can help distinguish @entity189 from @entity189 of the @entity235 hepatoid gland.
