Ethnicity and comorbidities in an overweight and XXXX multiethnic childhood cohort in Berlin.

@entity1 @entity28 @entity209 @entity3918 @entity413 @entity214
AIM: This study aims to analyse the association between ethnicity, elevated metabolic parameters and @entity209 ( @entity209 ) in a multiethnic cohort of overweight to @entity28 @entity1 and adolescents. METHODS: For 1053 @entity1 , standard deviation of body mass index (BMI-SDS) was calculated and metabolic parameters (fasting blood @entity413 , fasting insulin, homeostasis model assessment-IR, lipids, blood pressure) were measured. @entity209 was defined by WHO criteria. Bivariate and multivariate analyses were performed. Adjusted differences in BMI- @entity214 and metabolic parameters between different migration groups were assessed with linear regression models. The risk for @entity209 was calculated with multiple logistic regression models. RESULTS: Forty-eight per cent of the @entity1 were German, 25% Turkish and 27% had another ethnicity. Concerning weight status, 23% are overweight, 31% @entity28 and 46% extremely @entity28 with higher rates among the immigrant population. Multivariable models indicate significant associations between elevated metabolic parameters and higher BMI-SDS values. Overall prevalence of @entity209 was 32.3%. @entity209 was detected significantly more often among Turkish @entity1 (40.4%) compared to Germans (27.3%; p=0.02). Logistic regression analysis showed a greater risk for @entity209 with older age (OR=1.09; p=0.003) and Turkish ethnicity (OR=1.62; p=0.02). CONCLUSION: Nearly all @entity1 had symptoms of @entity209 , and 40% had @entity209 showing that this highly health-threatening condition is quite common. Therefore, effective therapy and prevention efforts must be developed for this high risk group. More migration-specific research regarding insulin resistance, @entity209 and Type 2 @entity3918 is needed.
