Anticardiolipin and anti-beta2glycoprotein-I antibodies in @entity1 with XXXX : comparison between Colombians and Spaniards.

@entity1 @entity882 @entity9500 @entity1252 @entity715 @entity12288
We studied the prevalence, isotype distribution, and clinical significance of anticardiolipin (aCL) and anti-beta2glycoprotein I (anti- @entity9500 ) antibodies in two populations of @entity1 with @entity1252 ( @entity1252 ), 160 Colombians and 160 Spaniards. All sera were tested in our laboratory by enzyme-linked immunosorbent assay (ELISA) for IgG, IgM, and IgA aCL, as well as IgG and IgM anti- @entity9500 . Positive results for at least 1 of the 3 aCL isotypes were found in 40 Colombians (25%) and 55 Spaniards (34%). IgG aCL was the predominant isotype in both populations. Positive results for at least 1 of the anti- @entity9500 isotypes were found in 34 Colombians (21%) and 29 Spaniards (18%). IgG anti- @entity9500 was the dominant isotype in Colombians, while IgM was predominant in Spaniards. Positivity for anti- @entity9500 in aCL-positive @entity1 was present in 77% in the Colombian group and 50% in the Spaniard group. Among Colombians, IgG aCL and anti- @entity9500 correlated with @entity715 , fetal loss, and @entity882 . Among Spaniards, IgG aCL and IgG anti- @entity9500 correlated with @entity715 , fetal loss, and @entity12288 . For detecting @entity715 and fetal loss, aCL ELISA was more sensitive than anti- @entity9500 in Spaniards, and anti- @entity9500 ELISA was more specific than aCL in both populations.
