Double Cortex Syndrome ( XXXX ): A Case Report.

@entity1 @entity4289 @entity410 @entity322 @entity75 @entity2133 @entity8568 @entity1092 @entity245 @entity12198 @entity71489 @entity2421 @entity15261 @entity302 @entity159 @entity848
Objective Approximately 5-10% of preschool age @entity1 are considered developmentally disabled. Brain Magnetic Resonance Imaging (MRI) plays a key role in the diagnostic evaluation in these @entity1 . Many congenital or acquired @entity75 are revealed with MRIs. Although the majority of these abnormalities are sporadic but @entity1 with @entity4289 or @entity4289 have sex-linked inheritance. We are going to present the first case in Iran from Ahvaz city, which was presented with @entity159 associated with @entity245 and finally diagnosed as @entity4289 , because @entity71489 cases especially for continuous or generalized form is rare. A 4.5-year-old developmentally delayed @entity1 was admitted for generalized tonic clonic @entity410 attack of 1 hr, upward gaze, @entity2133 , and @entity322 ( @entity159 ) in the @entity1 neurology ward. She had a history of recurrent @entity410 that @entity410 since she was 12 months of age and had frequent admissions for having recurrent @entity410 attacks. She was the only @entity1 of consanguineous parents with negative family history of any neurologic problems. She was a product of uneventful term pregnancy, vaginal delivery with a low Apgar score at birth who was admitted for six days in the neonatal ward for @entity2421 and @entity848 . At 4.5 years of age, she had HC: 45cm (<3%) Length: 102 cm (25-75%), and BW: 18kg (75%). She was able to sit, walk with support, speak a few words, and communicate with others. A physical exam was unremarkable. Lab data including CBC, blood biochemical, and urinalysis results were all within normal limits, but the electroencephalography (EEG) revealed generalized poly spike-wave discharges. A brain MRI showed @entity15261 , generalized @entity71489 , and @entity8568 . She was discharged home with oral @entity1092 and regular outpatient follow-ups. In the diagnostic evaluation of developmentally delayed and @entity302 @entity1 , a brain MRI is strongly recommended for accurate diagnosis of anomalies such as @entity12198 ( @entity71489 ) and others, because appropriate therapeutic management, prognosis, prevention, and genetic counseling for prenatal diagnosis are dependent on definite diagnosis of the proband case.
