Presentation of XXXX at a paediatric eye clinic in ghana.

@entity1 @entity154 @entity5 @entity1442 @entity3 @entity995
BACKGROUND: Retinobalstoma, the commonest childhood @entity5 , is usually diagnosed early with over 90% survival rate in developed countries. In developing countries, the diagnosis is late resulting in less than 50% survival. OBJECTIVE: To determine @entity995 stages at presentation and @entity1 ' outcomes. DESIGN: Retrospective case series. METHODS: The clinical and histopathological records of @entity1 with @entity995 seen from May 2004 to December 2005 were studied. Data was analysed for mode of presentation, laterality, clinical staging using Reese-Ellsworth (R-E) classification, @entity154 ( @entity154 ) for @entity3 , and @entity1 outcome. SETTING: Ophthalmology Unit, Korle-Bu Teaching Hospital, Ghana. RESULTS: Twenty-three @entity1 presented with @entity995 over the period. Males were 12(52.2%). The age range from 1 to 84 months, mean 36.3(  22.15) and median (36 months). Nineteen (82.6%) had unilateral and 4(17.4%) bilateral disease. The common clinical presentations were leukocoria in 20(87.0%), proptosis 8(34.8%), strabismus 5(21.7%) and red eye 5(21.7%). The clinical features were commensurate with R-E stage V in 20(87.0%) @entity1 , 2(8.7%) with orbital recurrence and 1(4.3%) with post-enucleation anophthalmos. HHRFs were present in 9(75%) enucleated eyes with invasion of optic nerve as the commonest site (7/9). The @entity1 were followed up for 1 day to 19 months. Eight abandoned treatment, 2 were discharged for palliative treatment, 2 out of 5 with @entity3 died and 6 had no metastases at their last visit. Common sites for @entity3 were the bone marrow, brain and orbit. CONCLUSION: Majority of the @entity1 presented with @entity1442 manifesting as leukocoria, proptosis, RE stages V disease and poor outcome.
