Long-Term Outcomes of Open and Video-Assisted Thoracoscopic Lung Lobectomy for the Treatment of Early Stage XXXX are Similar: A Propensity-Matched Study.

@entity1 @entity190 @entity5 @entity1149 @entity764
BACKGROUND: Generally, in retrospective studies, favourable short- and long-term outcomes for @entity1 after lung lobectomy for early stage @entity1149 ( @entity1149 ) using video-assisted thoracoscopic surgery (VATS) have been reported. However, the interpretation of lung lobectomy outcomes may be biased in retrospective settings. METHODS: We retrospectively reviewed @entity1 who underwent lung lobectomy for cT1-2N0M0 @entity1149 from 2001 to 2010. The outcomes of @entity1 who underwent VATS lobectomy were compared to those who underwent open lobectomy before and after performing propensity score matching. Preoperative covariates were entered when developing the propensity score-matching model. RESULTS: This study reviewed the outcomes of 101 VATS @entity1 and 184 open lobectomy @entity1 . Before propensity score matching, the VATS group had a higher mean age (p  <  0.0001), smaller solid @entity5 size (p  =  0.0042), similar whole @entity5 size (p  =  0.2082), and larger @entity5 -disappearance ratio (p  =  0.0007). The VATS group had a shorter mean operation time (p  =  0.0002), less @entity190 (p  <  0.0001), shorter @entity764 (p  =  0.0002), and shorter hospital stay (p  <  0.0001). As for long-term outcomes, the VATS group had higher disease-free, disease-specific, and overall survival rates (p values by log-rank test: 0.0049, 0.0154, and 0.032, respectively). After propensity score matching, all differences, except operation time, @entity190 , @entity764 , and hospital stay, were no longer significant. CONCLUSIONS: VATS lobectomy is less invasive than open lobectomy, but in terms of survival outcomes, VATS lobectomy was oncologically equivalent to open lobectomy. The oncological benefit of VATS reported by retrospective studies might be overestimated.
