Longitudinal assessment of early onset XXXX .

@entity1 @entity6223 @entity2521
The purpose of this study was to determine the clinical course of early onset @entity2521 and to investigate factors which may influence its clinical course. For the past 15 years we have been conducting a study of families with early onset @entity2521 , and have examined 142 localized @entity6223 and 185 severe generalized early onset @entity2521 @entity1 . In order to study the clinical course of early onset @entity2521 we recalled our subject population to determine their periodontal status. Forty (40) @entity1 with localized early onset @entity2521 (LJP) and 48 with generalized early onset @entity2521 (SP) were re-examined. The time since the most recent visit for LJP @entity1 was approximately 3 years and for SP @entity1 almost 4 years. LJP @entity1 who received periodontal therapy on the average gained periodontal attachment. In contrast, LJP @entity1 who did not receive therapy lost periodontal attachment. SP @entity1 lost periodontal attachment regardless of whether or not they had periodontal therapy. SP @entity1 also lost an average of one tooth during the approximately 4 years of observation. LJP @entity1 lost very few teeth with only 4 teeth being lost in 40 @entity1 . The results of this study suggest that localized @entity6223 is a stable disease in most individuals. In contrast, @entity1 with severe generalized early onset @entity2521 continued to lose both periodontal attachment and teeth.
