Effect of antibiotic and fluid resuscitation upon survival time in experimental XXXX .

@entity235 @entity204 @entity63
Acute massive @entity63 is an abdominal catastrophe. Prompt diagnosis and restoration of blood flow is essential; otherwise, massive intestinal resection occurs, leading to @entity204 or, in the survivors, intestinal cripples. In this study, the time of warm reversible @entity63 in the @entity235 intestine was explored. After this time was established, fluids and antibiotics were administered to note change in survival times. Massive @entity63 (superior mesenteric artery was clamped) was tolerated without @entity204 for five hours (20 @entity235 in each group). With six hours of @entity63 , a 10 per cent mortality rate occurred; with seven hours of @entity63 , a 90 per cent mortality rate occurred. These @entity235 had a maintenance of 75 milliliters of fluid administered per hour. Using this group of @entity235 as the control (that is, the group with seven hour clamping time of the superior mesenteric artery with maintenance intravenously administered replacement), fluids were given to @entity235 in the experimental group to keep the pulmonary artery wedge pressure at a normal value (average of 300 milliliters per hour). This group of @entity235 had an increased survival rate of 40 per cent (ten dogs). Antibiotics were given to the @entity235 in the experimental group both before and after clamping, increasing the over-all survival rate to more than 80 per cent (46 @entity235 ). Aggressive fluid replacement and antibiotic coverage may lengthen the so-called golden period in which @entity63 may be reversed by revascularization.
