Synchrotron nanoscopy imaging study of scalp hair in @entity0 XXXX and healthy individuals: Difference in medulla loss and cortical membrane enhancements.

@entity1 @entity5 @entity0
UNASSIGNED: Nanoscopic synchrotron X-ray imaging was performed on scalp hair samples of @entity1 with @entity0 and healthy individuals to investigate any structural differences as diagnostic tool. Hair strands were divided into 2-3 segments along the strands from root to tip, followed by imaging either in projection or in CT scanning with a monochromatic 6.78-keV X-ray using zone-plate optics with a resolving power of 60 nm. All the examined @entity5 hairs exhibited medulla loss with @entity5 stage-dependent pattern; complete loss, discontinuous or trace along the strands. In contrast, medullas were well retained without complete loss in the healthy hair. In the CT-scanned axial images, the cortical spindle compartments had no contrast in the healthy hair, but appeared hypointense in contrast to the surrounding hyperintense cortical membrane complex in the @entity5 hair. In conclusion, observation of medulla loss and cortical membrane enhancements in the hair strands of @entity0 @entity1 @entity5 hair, providing a new platform for further synchrotron X-ray imaging study of screening @entity0 @entity1 . Microsc. Res. Tech., 2015.    2015 Wiley Periodicals, Inc.
