Comparison of Measurement of Central Corneal Thickness with Spectral Domain Optical Coherence Tomography and Standard Ultrasonic Pachymeter in Premature XXXX .

@entity1 @entity2840
Purpose. To evaluate the repeatability of measurement of @entity2840 ( @entity2840 ) by spectral domain optical coherence (SD-OCT) in premature @entity1 and compare it to @entity2840 measurement by ultrasonic pachymetry (USP). Methods. Three @entity2840 measurements of the left eyes of 50 premature @entity1 were obtained by SD-OCT using the iVue system. 10 @entity2840 measurements of each 28 left eyes of 28 @entity1 were obtained by USP using the Pacscan 300P system. Bland-Altman plots were developed and the limit of agreement (LoA) was determined to compare the mean of the SD-OCT and USP measurements. Results. No statistically significant difference was found among the 3 @entity2840 measurements by SD-OCT. Both USP and SD-OCT have been performed for only left eyes of 28 of the 50 babies. Those results have been compared with each other. A statistically significant difference was found between the mean @entity2840 measurements by SD-OCT and USP (p < 0.05). The LoA between the SD-OCT and USP measurements ranged from 11.4 to -64.1. Conclusions. @entity2840 can be measured using the iVue SD-OCT system with a high level of repeatability. Although measurement of @entity2840 by SD-OCT and USP is highly correlated, the 2 systems cannot be used interchangeably in premature @entity1 .
