Central pancreatectomy: a technique for the resection of XXXX .

@entity1 @entity788 @entity548 @entity6 @entity5 @entity190 @entity660 @entity9451 @entity260 @entity8940 @entity45 @entity1821 @entity12679
HYPOTHESIS: Central pancreatectomy has been used sparingly because the spectrum of indications is quite narrow. Although historically used for traumatic pancreatic transection and chronic @entity788 , it currently is reserved for selective management of @entity660 that are benign or have low malignant potential. Varying morbidity rates have been published in the literature. Our objectives were to describe the technique and determine the safety and effectiveness of central pancreatectomy in the excision of benign or low-malignant potential lesions of the @entity9451 . DESIGN: Retrospective clinicopathologic data review. SETTING: The Mayo Clinic surgical index was used to identify procedures matched for central, median, middle, or middle segment pancreatectomy. @entity1 : Eight @entity1 (4 @entity1 , 4 @entity1 ) underwent central pancreatectomy between 1998 and 2004. INTERVENTION: @entity1 with @entity9451 or proximal body masses underwent central pancreatectomy at the Mayo Clinic, Rochester, Minn. MAIN OUTCOME MEASURES: @entity1 were followed up closely for @entity260 during the initial hospital admission. On follow-up, long-term endocrine and exocrine function were determined based on laboratory values and @entity1 history. RESULTS: Abnormalities included 3 islet cell @entity5 , 2 @entity12679 , a @entity8940 , a @entity45 , and a @entity1821 . Mean @entity5 size was 2.8 cm and mean operative time was 4.8 hours with a mean @entity190 of 381 mL. The most common complication was @entity788 (5 @entity1 [63%]). Reoperation was necessary in 2 @entity1 (25%), both secondary to @entity548 . There was no mortality or new-onset @entity6 . One @entity1 transiently required oral pancreatic enzyme supplementation. CONCLUSIONS: Central pancreatectomy may preserve endocrine and exocrine function. While mortality is low, in our experience, central pancreatectomy is associated with a high complication rate. The most common complication is @entity788 . Caution is necessary when using central pancreatectomy in the treatment of @entity660 . Surgeon experience is of utmost importance in this decision-making process as well as the technical aspects of central pancreatectomy. The precise role of central pancreatectomy in the management of benign or low-malignant potential lesions of the neck of the pancreas remains in evolution.
