Cribriform-morular variant of papillary carcinoma: the sporadic counterpart of XXXX . A case report with clinical and molecular genetic correlation.

@entity1 @entity1127 @entity1420 @entity2931 @entity5 @entity5822 @entity1412 @entity259
The increased incidence of @entity259 in @entity1412 ( @entity1412 ) @entity1 is well recognised. These @entity259 display distinctive clinicopathological features and generally show good prognostic outcome. Recently, @entity5 that share the morphological features of @entity1412 have also been described. In this report, we document a case of a @entity5 in a previously well, 46-year-old female. Histology revealed a circumscribed @entity5 composed of tubular, papillary, cribriform and solid areas. The @entity5 cells showed occasional nuclear grooves and rare nuclear inclusions. Immunohistochemistry showed positive staining with antibodies to cytokeratin AE1/AE3, @entity2931 and @entity1420 receptor proteins. Focal immunoreactivity was also noted with antibodies to thyroglobulin, epithelial membrane antigen, 34betaE12 and cytokeratin @entity5822 . The absence of @entity1127 on colonoscopy and germline mutation in the @entity1412 ( @entity1412 ) gene provides evidence that this @entity5 represents the sporadic counterpart of @entity1412 -associated @entity259 . The @entity1 is well with no evidence of disease 7 months following resection of the @entity5 . The differential diagnoses and molecular genetics of this @entity5 are discussed.
