A case of valproate intoxication with excessive XXXX .

@entity1 @entity410 @entity2657 @entity1092 @entity772 @entity653 @entity19014 @entity1662
A 29-year-old @entity1 , who had been treated with @entity1092 for 3 years because of generalized @entity410 , ingested a large amount of this drug in an attempt to suicide. The exact amount he had swallowed could not be determined. The @entity1 arrived in the intensive care unit in a deep @entity772 , was intubated, and artificially ventilated. He developed a massive @entity2657 , as proved by computerized tomography (CT). This was supported by electroencephalography (EEG). The measured value for the concentration of @entity1092 in serum was markedly elevated on the day of admission (2300 mumol/l; therapeutic range 350-700 mumol/l). Treatment with @entity19014 , @entity653 , and glucocorticoids was initiated. A second CT scan performed 9 days after admission showed a complete normalization and the EEG yielded a markedly improved pattern. At this point the @entity1 slowly regained @entity1662 . We conclude that in @entity1 with an acute @entity1092 intoxication, care should be taken with regard to the development of a severe @entity2657 , which in the reported case could be treated successfully.
