Pelvic control following external beam radiation for surgical stage I XXXX .

@entity1 @entity1204 @entity5 @entity102 @entity420 @entity1744
PURPOSE: To determine if postoperative external pelvic radiation (EBRT), without vaginal brachytherapy, is sufficient to prevent vaginal cuff and pelvic recurrences in @entity1 with surgical Stage I @entity1204 ( @entity420 ). METHODS AND MATERIALS: The records of 122 @entity1 with surgical @entity1204 were reviewed. There were 87 @entity1 with @entity420 who received EBRT alone and are the subject of this study. Their radiation records were reviewed. All @entity1 underwent exploration, total abdominal hysterectomy, and bilateral salpingo-oophorectomy (TAH BSO), and pelvic and paraaortic lymph node sampling. They were staged according to the FIGO 1988 surgical staging system recommendations. Postoperatively, pelvic EBRT was administered by megavoltage equipment using four fields, to a total dose of 45 to 50.4 Gy. Actuarial survival and disease free survival were calculated according to Kaplan-Meier Method. RESULTS: Twenty-seven @entity1 with Stage IA Grade 1 or 2 @entity420 with less than one-third myometrial invasion, who did not receive EBRT, and eight @entity1 with histology other than @entity420 (i.e., serous papillary, mucinous, etc.) were not included in the study. For the remaining 87 @entity1 who are in the study group, the median follow-up was 52 months (range: 12-82 months). The 5-year overall survival for these 87 @entity1 was 92%, with a disease-free survival of 83%. There were no @entity5 recurrences in the upper vagina or in the pelvis. Two @entity1 developed @entity1744 (no surgery required), and one @entity1 developed @entity102 . CONCLUSION: Adjuvant external pelvic radiation, without vaginal brachytherapy, prevents pelvic and vaginal cuff recurrences in surgical Stage I endometrial @entity420 .
