Malnutrition assessed through phase angle and its relation to prognosis in @entity1 with compensated XXXX : A prospective cohort study.

@entity1 @entity82 @entity409 @entity3147 @entity1575
BACKGROUND: Malnutrition is a frequent complication of @entity82 and it has been associated to more severe disease and development of complications. Phase angle is a bedside reliable tool for nutritional assessment based on conductivity properties of body tissues. AIM: To evaluate the association between @entity3147 assessed through phase angle and mortality in @entity1 with @entity1575 . METHODS: We performed a prospective cohort study in a tertiary care centre; 249 @entity1 were enrolled with 48 months of follow-up. Clinical, nutritional ( @entity3147 =phase angle <=4.9  ) and biochemical evaluations were performed. Student's t-test and   (2) method were used as appropriate. Kaplan-Meier curves and multivariate Cox regression were used to evaluate mortality. RESULTS: Mean follow-up was 33.5 months. Survival analysis showed higher mortality in the malnourished group compared to the well-nourished group (p=0.076), Kaplan-Meier curves were further stratified according to compensated and decompensated status showing higher mortality in compensated @entity1 according to @entity1 -Pugh (p=0.002) and Model for End-Stage @entity409 score (p=0.008) when @entity3147 was present. Multivariate analysis showed that @entity3147 was independently associated with mortality (HR=2.15, 1.18-3.92). CONCLUSIONS: In our cohort, @entity3147 was independently associated with mortality. This is the first study showing higher mortality in malnourished compensated cirrhotic @entity1 .
