@entity3745 immunostaining in XXXX : relationship to the degree of differentiation and cell type.

@entity5 @entity189 @entity1358 @entity3745 @entity259
A series of 47 primary and seven metastatic @entity259 , including well, moderately and poorly differentiated, were tested for @entity3745 (Tg) using immunohistology. In addition, three combined follicular @entity189 , 17 @entity189 and @entity1358 metastatic to the thyroid were examined. Only two @entity189 did not stain for @entity3745 . Some @entity5 differences in Tg staining were found but there was no absolute correlation between this and the degree of @entity5 differentiation. The two @entity5 that failed to stain for Tg were poorly differentiated; @entity3745 positive poorly differentiated @entity5 demonstrated a clearly weaker staining pattern for Tg. All but one of 15 @entity189 stained positively for Tg but the staining intensity was often weak. Five of six @entity1358 were positive for Tg but the staining reaction was generally faint and there were often large areas devoid of positive cells. Positive staining was demonstrated in the differentiated areas of combined follicular @entity189 . @entity189 and metastatic @entity1358 gave negative results. @entity3745 is a reliable marker for @entity259 but the patchy staining pattern, particularly in the less well-differentiated @entity5 may produce less reliable results in small biopsies.
