Natural history and prognosis of XXXX : report of a multi-institutional study in Japan. The group for the study of prognosis of @entity302 in Japan.

@entity1 @entity410 @entity16 @entity51 @entity302 @entity716 @entity1314 @entity25
A multi-institutional study on the prognosis of @entity1 with @entity302 was performed in Japan from 1975 to 1977, including 20 institutions. The outcome of @entity302 and social adjustment 10, 5, and 3 years after the onset of the illness was studied in three different groups of @entity302 @entity1 , respectively. The number of successfully followed-up cases was 1,868 in total, follow-up rate being 42%. The data were analyzed statistically by use of analysis of variance. The rate of remission of @entity410 in all was 58.3% and the rate of normal social adjustment 62.6%. The remission rate showed no significant difference among the 10-, 5-, and 3-year outcome groups. The study on the outcome of @entity410 control indicated that the prognosis of @entity410 control is more favorable (a) in idiopathic than in residual or symptomatic @entity302 ; (b) in @entity1 with onset before 10 years of age than in those with onset after 10 years; (c) in @entity1 with less frequent @entity410 ; (d) in @entity25 than in waking and diffuse @entity302 ; (e) in @entity1 who started treatment within 1 year of onset of @entity410 ; (f) in @entity1 with single-type partial @entity410 than in those with partial @entity410 combined with @entity410 ; (g) in @entity1 without high grade EEG background abnormality; and (h) in @entity1 without @entity16 , @entity51 , @entity1314 , or @entity716 symptoms. Factors that determine the prognosis of social adjustment were almost similar to those for remission of @entity410 . There was a close correlation between the outcome of @entity410 control and that of social adjustment. Correlation coefficient between follow-up rate and remission rate in 15 of the 20 collaborated institutions was 0.55 (p less than 0.05), showing a tendency that the remission rate becomes higher as the follow-up rate is raised.
