Adherence of @entity526 and Proteus mirabilis to XXXX transitional cells.

@entity1 @entity9700 @entity1290 @entity2885 @entity2335 @entity293 @entity526
This study utilizes a light microscopy assay for bacterial adherence to @entity1 male transitional cells. Prior light microscopy studies have used voided squamous cells, periurethral cells or scraped vaginal cells, which are less representative of the cells lining the majority of the urinary tract. Using a modification of previous bacterial adherence assays, the mean adherence for 28 strains of @entity526 in 92 bacteria-cell incubations was 10.2 +/- 11.5 (standard deviation) bacteria per cell. The mean adherence for 20 strains of @entity9700 in 60 bacteria cell incubations was 8.1 +/- 11.4. No statistically significant difference in adherence between @entity526 and @entity9700 was found (p greater than 0.05). Studies comparing the adherence of @entity526 isolated from the urine of @entity1 with @entity2885 (eight strains), @entity2335 (10 strains) and anal swabs of females without @entity293 (10 strains), showed no statistically significant differences in mean adherence (p greater than 0.05). However, there was a trend toward higher adherence in the more virulent groups. Experiments comparing the adherence of @entity9700 isolated from @entity1290 to @entity9700 isolated from anal swabs of female @entity1 without history of @entity9700 UTI revealed no statistically significant differences in mean adherence between the two groups (p greater than 0.05). These data do not support previous contentions that @entity9700 adhere poorly to @entity1 transitional cells. The absence of a significant difference in adherence among strains of @entity526 and @entity9700 that differ in clinical pathogenicity suggests that factors other than adherence contribute to their virulence.
