Study on Diastolic Dysfunction in Newly Diagnosed XXXX and its Correlation with Glycosylated Haemoglobin (HbA1C).

@entity4051 @entity1 @entity2175 @entity712 @entity296 @entity101 @entity6 @entity63 @entity13088 @entity1002 @entity417 @entity177 @entity358 @entity299 @entity340 @entity165
INTRODUCTION: @entity1002 ( @entity1002 ) represents the first stage of @entity13088 preceding changes in systolic function, reinforcing the importance of early examination of ventricular function in individuals with @entity6 ( @entity6 ). This cross-sectional study was conducted to determine the incidence of asymptomatic @entity1002 in newly diagnosed normotensive cases of type 2 @entity6 subjects, and its relation to glycosylated haemoglobin (HbA1C), age at the time of diagnosis, body mass index (BMI) and serum total @entity165 . AIM AND OBJECTIVE: To study the incidence of @entity1002 ( @entity1002 ) and its correlation with @entity4051 C in normotensive, newly diagnosed type 2 @entity6 @entity1 . MATERIALS AND METHODS: This cross-sectional study was done in western U.P. on 100 @entity1 of newly diagnosed (within 1 month) type 2 @entity6 between @entity1 30 and 60 years of age, visiting the Medicine and Endocrinology outpatient Department of LLRM Medical College, Meerut. @entity1 with @entity2175 and already taking antidiabetic treatment, @entity299 like @entity340 , @entity63 and @entity101 , @entity712 , @entity296 , @entity177 , @entity358 , severe @entity417 and haemoglobinopathies were excluded from the study. These @entity1 were informed about the study and informed consent was obtained before proceeding with the investigations. @entity1 selected were evaluated with relevant investigations like fasting and post prandial blood sugar, HbA1C level, lipid profile and 2D echocardiography to assess @entity1002 . These selected @entity1 were divided in 2 groups; one with @entity1002 ( @entity1002 ) and second group of subjects without @entity1002 . Various parameters like HbA1C, age, body mass index and serum @entity165 were evaluated between these 2 groups. Statistical analysis was performed using Student t-test, Chi-square and Fisher Exact-test. RESULTS: Out of 100 @entity1 65 were males and 35 females. Mean age of the population was 50.08    6.32 years. Overall incidence of @entity1002 was 41%. Grade 1 @entity1002 was most common. Mean @entity4051 C level of @entity1002 group was found higher as compared to those without @entity1002 . CONCLUSION: @entity1002 is very common at the time of diagnosis of type 2 @entity6 even in normotensive @entity1 independent of confounding effect of @entity101 , @entity63 and BMI. @entity4051 C and age, were found to be strong indicators of @entity1002 in newly diagnosed cases of Type 2 @entity6 .
