Comparison of invasive and non-invasive pressure gradients in aortic XXXX .

@entity1 @entity8521 @entity1498 @entity2333 @entity6127
BACKGROUND: @entity8521 can be evaluated by catheter peak-to-peak gradient or by Doppler peak instantaneous pressure gradient. Previous studies have shown moderate correlation in @entity1498 , but few have assessed correlation in @entity1 with more complex aortic reconstruction. METHODS: We carried out retrospective comparison of cardiac catheterisations and pre- and post-catheterisation echocardiograms in 60 @entity1 with native/recurrent @entity1498 or aortic reconstruction. @entity8521 was defined as peak-to-peak gradient    25 mmHg in @entity1 with native/recurrent @entity1498 and    10 mmHg in aortic reconstruction. RESULTS: Diastolic continuation of flow was not associated with aortic @entity6127 in either group. Doppler peak instantaneous pressure gradient, with and without the expanded Bernoulli equation, weakly correlated with peak-to-peak gradient even in @entity1 with a normal cardiac index (r=0.36, p=0.016, and r=0.49, p=0.001, respectively). Receiver operating characteristic curve analysis identified an area under the curve of 0.61 for @entity1 with all types of obstruction, with a cut-off point of 45 mmHg correctly classifying 64% of @entity1 with @entity6127 (sensitivity 39%, specificity 89%). In @entity1 with aortic arch reconstruction who had a cardiac index    3 L/min/m2, a cut-off point of 23 mmHg correctly classified 69% of @entity1 (71% sensitivity, 50% specificity) with an area under the curve of 0.82. CONCLUSION: The non-invasive assessment of @entity2333 remains challenging. The greatest correlation of Doppler indices was noted in @entity1 with aortic reconstruction and a normal cardiac index.
