Analysis of the long-term results of our combination therapy for maxillary @entity5 , with particular reference to treatment of T4 and N1-3 maxillary XXXX .

@entity1 @entity5 @entity73 @entity957 @entity3 @entity204 @entity1487
To evaluate how far the long-term survival rate could be improved by maximum combination of chemotherapy, radiotherapy, and surgery, we have performed a trial combination therapy consisting of Linac X-ray irradiation (200 rads X 30) and intraarterial infusion chemotherapy ( @entity1487 250 mg X 15), followed by sufficiently extensive maxillectomy and primary reconstruction. The 5-year crude and relative survival rate of 70 @entity1 were 64.2 and 72.1% respectively. The 5-year crude survival rate in cases with @entity957 was 73.1%. Twelve out of 70 @entity1 died of @entity5 . Local recurrence was seen in 6 cases and the most frequent cause of @entity204 was distant @entity3 which was seen in 25% of T4N0 cases and in 57% of T2-3N1-3 cases. The elderly @entity1 over 71 years occupied 29.1% of the total cases. The 3-year and 5-year crude survival rates in these elderly @entity1 were 75 and 50% respectively. Death due to @entity5 was seen only in 3 @entity1 and the most frequent cause of @entity204 was due to senility and other unrelated causes. As far as @entity957 is concerned, the post-therapeutic courses of our combination therapy have been satisfactory. However further revision of the trial therapy was deemed necessary in T4 and N1-3 maxillary @entity5 . By covering the entire wound surface after total and extended total maxillectomy by a thick flap, the post-operative @entity73 due to scar contracture of the wound could be effectively prevented.(ABSTRACT TRUNCATED AT 250 WORDS)
