XXXX in @entity6275 . Report of a case and review of the literature.

@entity1 @entity6275 @entity174 @entity5 @entity1066 @entity957 @entity4034 @entity3
Malignant change at the site of a @entity6275 , a rare condition, is reported in a 45-year-old @entity1 , along with a review of the literature. This @entity1 with a 30-year history of @entity6275 of the right femur and an intermittently discharging sinus had a large abscess in the lower thigh. The abscess was drained, and an @entity1066 developed at the mouth of the sinus tract. Soon afterward, he sustained a pathologic @entity174 through the lower femur. Biopsy specimens of the @entity1066 showed a well-differentiated @entity957 . An amputation was performed at the level of the proximal 10 cm of the femur. The @entity1 remains well 18 months later with no clinical or radiologic evidence of @entity3 . Changes in character of a previously innocuous @entity4034 sinus tract should arouse suspicion of @entity5 . Biopsy of various depths of the sinus tract, including the bone marrow, is essential. Early amputation for @entity957 is indicated and offers a good prognosis.
