A study of intermediate lobe differentiation in the XXXX pituitary gland.

@entity1 @entity4545 @entity21422 @entity5 @entity699 @entity977
The immunohistochemical demonstration of neurofilament (NF) polypeptide was used to identify nerves in a series of 17 @entity977 . NF-positive fibres were present in two out of five @entity21422 sited deep in the anterior lobe, in one out of five sited in the intermediate zone and in two out of seven non- @entity21422 . Such nerve fibres were often seen in relation to blood vessels. The distribution of @entity4545 immunoreactive cells was examined in 25 normal pituitaries and in 23 cases of @entity699 . Such cells were scattered throughout the normal gland and there was no increase in numbers in pregnancy. @entity4545 was demonstrated in 18 @entity21422 in @entity699 . There was no correlation with the site of the @entity5 or the presence of nerve fibres. @entity4545 cells were distributed normally in the para-adenomatous gland. Crooke's hyaline change and @entity4545 coexisted in some corticotrophs. These findings support the concept that 'intermediate lobe' function, as found in animals, has no discrete anatomical location in @entity1 .
