Quality of Life and Physical Function in Older XXXX on Dialysis: A Comparison of Assisted Peritoneal Dialysis with Hemodialysis.

@entity1 @entity308 @entity298 @entity6
BACKGROUND AND OBJECTIVES: In-center hemodialysis (HD) is often the default dialysis modality for older @entity1 . Few centers use assisted @entity298 ( @entity298 ), which enables treatment at home. This observational study compared quality of life (QoL) and physical function between older @entity1 on assisted @entity298 and HD. DESIGN, SETTING, @entity1 , _ MEASUREMENTS: @entity1 on assisted @entity298 who were >60 years old and on dialysis for >3 months were recruited and matched to @entity1 on HD (needing hospital transport) by age, sex, @entity6 , dialysis vintage, ethnicity, and index of deprivation. Frailty was assessed using the Clinical Frailty Scale. QoL assessments included Hospital Anxiety and @entity308 Scale (HADS), Short Form-12, Palliative Outcomes Symptom Scale (renal), Illness Intrusiveness Rating Scale, and Renal Treatment Satisfaction Questionnaire (RTSQ). Physical function was evaluated by Barthel Score and timed up and go test. RESULTS: In total, 251 @entity1 (129 @entity298 and 122 HD) were recruited. In unadjusted analysis, @entity1 on assisted @entity298 had a higher prevalence of possible @entity308 (HADS>8; @entity298 =38.8%; HD=23.8%; P=0.05) and higher HADS @entity308 score (median: @entity298 =6; HD=5; P=0.05) but higher RTSQ scores (median: @entity298 =55; HD=51; P<0.01). In a generalized linear regression model adjusting for age, sex, comorbidity, dialysis vintage, and frailty, assisted @entity298 continued to be associated with higher RTSQ scores (P=0.04) but not with other QoL measures. CONCLUSIONS: There are no differences in measures of QoL and physical function between older @entity1 on assisted @entity298 and comparable @entity1 on HD, except for treatment satisfaction, which is higher in @entity1 on @entity298 . Assisted @entity298 should be considered as an alternative to HD for older @entity1 , allowing them to make their preferred choices.
