Endoscopic, transmural drainage and necrosectomy for walled-off pancreatic and peripancreatic XXXX is associated with low mortality - a single-center experience.

@entity1 @entity788 @entity39 @entity5990 @entity204
OBJECTIVE: Endoscopic transmural drainage and necrosectomy (ETDN) is a promising alternative to percutaneous drainage and surgical intervention in the treatment of walled-off pancreatic and peripancreatic necroses (WONs). We assessed the outcome and safety profile of ETDN in a single-center @entity1 cohort. MATERIALS AND METHODS: In November 2005, ETDN for WON was introduced in our tertiary referral center. During a 6-year period (Nov 2005-Nov 2011), we retrospectively collected data on all @entity1 who underwent ETDN. RESULTS: Eighty-one @entity1 were treated with ETDN (median age 54, 52 @entity1 ). @entity5990 were the predominant etiology of @entity788 (41%), followed by alcohol (33%). Median time from debut of symptoms to first endoscopic treatment was 44 (9-246) days. Culture-proven infected @entity39 was found in 71% of the cases. Twenty-three @entity1 (28%) required admission in intensive care unit. The technical and clinical success rates were 99% and 89%, respectively. Procedure-related complications occurred in 10 (12%) @entity1 , of which 1 was procedure-related @entity204 . In-hospital mortality was 11%. CONCLUSION: ETDN in @entity1 with @entity788 and infected @entity39 performed in a single, high-volume center has an acceptable safety profile and is associated with a low mortality.
