Clinical Utility of Diagnostic Laboratory Tests in XXXX with Acute Pancreatitis: A Retrospective Investigation in a Primary Care Hospital.

@entity66 @entity656 @entity235 @entity3929 @entity25587
BACKGROUND: @entity656 ( @entity656 ) occurs frequently in @entity235 , but most previous studies examining the diagnosis of @entity656 have used data from secondary care hospitals. HYPOTHESIS/OBJECTIVES: The aim of this study was to investigate the clinical utility of diagnostic laboratory tests in @entity235 with @entity656 in a primary care hospital. ANIMALS: Sixty-four @entity235 with clinical signs suggestive of @entity656 diagnosed with @entity66 ( @entity66 ) or @entity656 . METHODS: Medical records were retrospectively reviewed, including diagnostic laboratory tests considered potentially useful in the diagnosis of @entity656 . The diagnostic accuracy of amylase and FUJI DRI-CHEM lipase (FDC lip) were investigated using receiver operating characteristics (ROC). In addition, we verified whether diagnostic laboratory tests were useful for evaluating duration of hospitalization and as biomarkers for monitoring recovery. RESULTS: Activities of amylase and FDC lip were significantly higher in the @entity656 group than in the @entity66 group (P = .001, P < .001, respectively). The sensitivity of FDP lip activity for diagnosing @entity656 was 100% (95% confidence interval [CI], 87.7-100%); the specificity was 89.5% (95% CI, 66.9-98.7%). Area under the ROC curve for FDC lip activity was 0.98 (95% CI, 0.93-1). High @entity3929 aminotransferase (ALT) activity was associated with extended duration of hospitalization (P = .04). A significant difference in @entity25587 ( @entity25587 ) concentration before and 5 days after treatment was found (P = .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Measurement of FDC lip activity appears useful for diagnosing @entity656 . High ALT activity might be associated with prolonged duration of hospitalization, and @entity25587 might be useful as a biomarker for monitoring recovery from @entity656 .
