The role of prophylactic antibiotics on XXXX in elective laparoscopic cholecystectomy.

@entity1 @entity281 @entity5394 @entity8509
BACKGROUNDS/AIMS: Although laparoscopic cholecystectomy is a common and widely accepted technique, the use of prophylactic antibiotics in elective laparoscopic cholecystectomy still remains controversial. The aim of this study is to determine whether prophylactic antibiotics could prevent @entity281 after elective laparoscopic cholecystectomy and to identify any risk factors for @entity281 . METHODS: This study included 471 @entity1 undergoing laparoscopic cholecystectomy between January 2009 and May 2012. Period 1 @entity1 (279) received second generation @entity8509 1 g intravenously after induction of anesthesia, and @entity5394 @entity1 (192) were not given prophylactic antibiotics. The characteristics and surgical site infections of the @entity1 were compared and analyzed. RESULTS: The overall rate of @entity281 was 1.69% for the total of 471 @entity1 . The incidence of @entity281 was similar for the two Periods: 5 of 279 @entity1 (1.79%) in Period 1, 3 of 192 @entity1 (1.56%) in @entity5394 (p=0.973). All of the @entity1 with surgical site infections were well treated under conservative treatments without any sequelae. The preoperative albumin level (p=0.023) contributed to @entity281 . CONCLUSIONS: Prophylactic antibiotics are not necessary for elective laparoscopic cholecystectomy but @entity1 in poor nutritional state with low albumin level should consider prophylactic antibiotics.
