[Preferential proliferation of natural killer cells with bone XXXX cells in @entity1582 ].

@entity1 @entity1582 @entity379 @entity1199 @entity236
We examined proliferation of natural killer (NK) cells in 10 day mixed culture of peripheral blood mononuclear cells (PBMC) from healthy subjects with irradiated bone @entity236 cells (BMMC) with @entity1582 . In culture, NK cells increased with 9.5-fold. However, no increase was observed in T cells. The NK cell proliferating activity of PBMC stimulated with BMMC was higher than that of @entity1199 . NK cells at a purity of 90% or higher purity were collected from 10 day culture. Proliferation of these NK cells was stimulated by the addition of @entity1199 but was suppressed by the addition of antibody coated erythrocyte (EA). @entity379 production was negligible in cultures of these NK cells alone but was marked in cultures with EA stimulate @entity379 production. Next, the NK cell obtained as above showed marked NK activity against K 562 cells, and this activity was further enhanced by the addition of @entity1199 . Also, while NK cells, these NK cells had some activity against Daudi cells and it was enhanced by the addition of @entity1199 . These results also suggest the presence of unknown cytokines with NK cell proliferating activities in the bone marrow of @entity1 with @entity1582 .
