Analysis of P wave and P dispersion in XXXX with secundum atrial septal defect.

@entity1 @entity384 @entity2438 @entity955 @entity13169
BACKGROUND: P maximum and P dispersion are evaluated as predictors of @entity955 in adults. In this study, these variables are being investigated in @entity1 with secundum @entity2438 in comparison with that of normal controls and in relation to size of @entity2438 and the presence or absence of @entity384 . METHODS: Ninety-four @entity1 with isolated secundum @entity2438 (33 @entity1 , 60 @entity1 ; mean +/- SD age at diagnosis 2.9 +/- 4.1 years) and 65 age-matched controls (mean +/- SD age 4.2 +/- 4.2 years) were evaluated. Resting 12-lead ECG was used to measure P waves from which P maximum and P dispersion (difference between maximum and minimum P-wave duration) were derived. @entity2438 @entity1 were arbitrarily subgrouped according to @entity2438 sizes (small: 1-3 mm, moderate: 4-7 mm, large: > or = 8 mm). The presence of right @entity384 was noted from echocardiography. RESULTS: @entity1 with @entity2438 had significantly longer mean P dispersion compared to controls (P dispersion: 30.2 +/- 11.1 vs 26.4 +/- 6.6 ms, P = 0.008). Mean P maximum and P dispersion were significantly prolonged with increasing @entity2438 size (P < 0.001). @entity1 with right @entity384 had significantly longer P maximum (102.3 +/- 15.2 vs 82.8 +/- 13.4 ms, P < 0.001) and larger P dispersion (36.1 +/- 12.5 vs 27.6 +/- 9.4 ms, P = 0.003) compared to those without right @entity384 . CONCLUSION: Prolonged @entity13169 time and inhomogeneity of @entity13169 may possibly be present in @entity1 with moderate to large sized @entity2438 and in those with @entity384 .
