Estimating glomerular filtration rate in XXXX subjects.

@entity1 @entity8 @entity28 @entity740 @entity1011
The glomerular filtration rate (GFR) can be estimated by an equation that incorporates @entity1 ' age, gender, @entity1011 and weight or, ideally, lean body mass (LBM). However, measuring LBM is not easy if the @entity1 is @entity28 . The aim was to determine an acceptable bedside method for GFR estimation in @entity28 @entity1 . In 82 @entity28 Caucasian outpatients, anthropometric and other characteristics were collected including LBM by impedance analysis. Estimates of GFR were compared with a reference equation (CCGLBM) using Bland-Altman plots, correlation analysis and an independent sample t-test. The @entity1 (72% female) were aged 43.1  12.7 years with BMI 47.0  8.0kg/m(2), height 168.4  9.4cm and serum @entity1011 70.3  25.7 M. The GFR estimated by the CCGLBM equation was 98.2  33.6ml/min compared to other equations which ranged from 100.0  22.8 to 218.4  85.5ml/min. Any equation incorporating actual body weight overestimated the GFR by >120ml/min (p<0.001) with a significant fixed proportional bias (p<0.001). For GFRs between 20 and 180ml/min, an equation using ideal body weight (CCGIBW) equated to the CCGLBM estimate. The Modified Diet in @entity8 and @entity740 Epidemiology Collaboration equations performed as well as the CCGLBM in estimating GFR but with proportional bias (p<0.001). Considering the ease of calculation of the CCGIBW at the bedside, it has a role in GFR estimation of @entity28 inpatients.
