Impact of several antibiotics and XXXX on the volatile fatty acid degradation, methanogenesis and community structure during thermophilic anaerobic digestion.

@entity72039 @entity801 @entity598 @entity45940 @entity5154 @entity1215 @entity1718
The main aim of the present study was to gain insight into the stability of an anaerobic digestion process suffering from exposure to antibiotics and the methanogenic inhibitor @entity72039 ( @entity45940 ). For this purpose, eleven antibiotics and @entity45940 were investigated with regard to the degradation of volatile @entity1718 (VFAs), methanogenesis, and impact on the microbial community structure. Only @entity5154 , @entity801 , @entity1215 , and @entity45940 showed complete inhibitions of VFA degradations. This points to distinct interferences with important trophic degradation cascades. Based upon DGGE and sequencing approaches, Methanosarcina spp. were severely influenced by the treatments while hydrogenotrophic methanogens were less affected. Interestingly, @entity45940 and @entity5154 inhibited the degradation of @entity598 while only @entity45940 inhibited methanogenesis completely. It seems that Methanosarcina spp. were mandatory for the degradation of @entity598 at high rates. The present results highly emphasize the detrimental effects of antimicrobial compounds with the potential to significantly inhibit the anaerobic digestion.
