Updated experiences with minimally invasive McKeown esophagectomy for XXXX .

@entity1 @entity834 @entity5 @entity190 @entity358 @entity418
AIM: To update our experiences with minimally invasive McKeown esophagectomy for @entity418 . METHODS: We retrospectively reviewed the medical records of 445 consecutive @entity1 who underwent minimally invasive McKeown esophagectomy between January 2009 and July 2015 at the @entity5 Hospital of Chinese Academy of Medical Sciences and used 103 @entity1 who underwent open McKeown esophagectomy in the same period as controls. Among 375 @entity1 who underwent total minimally invasive McKeown esophagectomy, 180 in the early period were chosen for the study of learning curve of total minimally invasive McKeown esophagectomy. These 180 minimally invasive McKeown esophagectomies performed by five surgeons were divided into three groups according to time sequence as group 1 (n = 60), group 2 (n = 60) and group 3 (n = 60). RESULTS: @entity1 who underwent total minimally invasive McKeown esophagectomy had significantly less intraoperative @entity190 than @entity1 who underwent hybrid minimally invasive McKeown esophagectomy or open McKeown esophagectomy (100 mL vs 300 mL vs 200 mL, P = 0.001). However, there were no significant differences in operation time, number of harvested lymph nodes, or postoperative morbidity including incidence of @entity358 and @entity834 between total minimally invasive McKeown esophagectomy, hybrid minimally invasive McKeown esophagectomy and open McKeown esophagectomy groups. There were no significant differences in 5-year survival between these three groups (60.5% vs 47.9% vs 35.6%, P = 0.735). @entity1 in group 1 had significantly longer duration of operation than those in groups 2 and 3. There were no significant differences in intraoperative @entity190 , number of harvested lymph nodes, or postoperative morbidity including incidence of @entity358 and @entity834 between groups 1, 2 and 3. CONCLUSION: Total minimally invasive McKeown esophagectomy was associated with @entity190 and comparable short term and long term survival compared with hybrid minimally invasive McKeown esophagectomy or open Mckeown esophagectomy. At least 12 cases are needed to master total minimally invasive McKeown esophagectomy in a high volume center.
