Use of the neutrophil to lymphocyte ratio for prediction of in-stent restenosis in XXXX .

@entity75 @entity453 @entity1 @entity65
OBJECTIVE: Percutaneous coronary interventions (PCI) are the preferred treatment for @entity453 , even though the development of in-stent restenosis (ISR) continues to be an important complication. Neutrophil to lymphocyte ratio (NLR) is indicative of the inflammatory process and can predict the short- and long-term prognosis of @entity65 . We investigated the relationship between ISR development and neutrophil-lymphocyte ratio (NLR) in @entity75 in stable @entity453 ( @entity453 ) @entity1 . @entity1 AND METHODS: We analyzed the clinical and angiographic data of 181 consecutive stable @entity453 @entity1 who had undergone successful PCI to the true bifurcation lesion from January 2010-December 2012. @entity1 were divided into two groups based on the development of ISR (group 1, ISR -; group 2, ISR +). RESULTS: NLRafter (p < 0.001) and NLR   (p < 0.001) were significantly higher in group 2. NLR   was found to be significant independent predictor of ISR in the multivariate logistic regression analysis. A NLR   level > 0.58 mg/dL had 81.8% sensitivity and 93.5% specificity for the prediction of ISR, as identified by the ROC curve. A NLRafter level > 3.43 predicted ISR with 45.5% sensitivity and 95.8% specificity. The comparison of ROC curve analysis demonstrated that NLR   was the strongest independent predictor of ISR (p = 0.001). CONCLUSIONS: As a result, although drug eluting stent implantation is known to be recommended in the bifurcation lesion PCI in worldwide, we want to emphasize the usage of the NLR values in the prediction of ISR. So, we think that NLR   levels may be a useful marker for the prediction of ISR in @entity1 who undergo bifurcation PCI.
