XXXX of mammary stroma.

@entity1 @entity455 @entity0 @entity9844 @entity5 @entity1373 @entity5426
Grossly circumscribed, nonhemorrhagic breast masses consisting of mammary stromal proliferations that simulated @entity455 were studied in nine @entity1 . Histologically, a striking pattern, which appeared to consist of complex inter-anastomosing channels lined by slender spindle cells, was present in the mammary parenchyma. The importance of this benign lesion, referred to as @entity9844 of mammary stroma, is its distinction from @entity5426 . The @entity1 ranged in age from 22 to 52 years; all were premenopausal. Each presented with a palpable unilateral mass, measuring up to 7 cm in diameter. The @entity1 were treated by excisional biopsy and remained well for up to 2.5 years after excision. One @entity1 had two local recurrences within one year of the original excision, and a second @entity1 had a local recurrence at 14 months. No @entity1 had another concurrent or metachronous @entity0 or other organ, and no abnormal hormonal status was found. Complete local excision appears to be adequate treatment. It remains to be determined whether this is a @entity5 . However, there is no evidence that it is a precursor of @entity5426 , and ultrastructural observations demonstrate that the spaces found in the lesion are not true vascular channels. Rather, they appear to arise by a process that involves disruption and separation of stromal collagen fibers. Since small foci of this change are common in hyperplastic breast tissue from premenopausal @entity1 , it is likely that the development of a discrete @entity5 with this pattern represents an exaggerated form of @entity1373 .
