The Montreal Cognitive Assessment and the mini-mental state examination as screening instruments for XXXX : item analyses and threshold scores.

@entity303 @entity73 @entity2414 @entity15818
AIMS: To perform an item analysis of the Montreal Cognitive Assessment ( @entity15818 ) versus the Mini-Mental State Examination (MMSE) in the prediction of @entity73 , and to examine the characteristics of different @entity15818 threshold scores. METHODS: 135 subjects enrolled in a longitudinal clinicopathologic study were administered the @entity15818 by a single physician and the MMSE by a trained research assistant. Subjects were classified as cognitively impaired or cognitively normal based on independent neuropsychological testing. RESULTS: 89 subjects were found to be cognitively normal, and 46 cognitively impaired (20 with @entity303 , 26 with mild @entity73 ). The @entity15818 was superior in both sensitivity and specificity to the MMSE, although not all @entity15818 tasks were of equal predictive value. A @entity15818 threshold score of 26 had a sensitivity of 98% and a specificity of 52% in this population. In a population with a 20% prevalence of @entity73 , a threshold of 24 was optimal (negative predictive value 96%, positive predictive value 47%). CONCLUSION: This analysis suggests the potential for creating an abbreviated @entity15818 . For screening in primary care, the @entity15818 threshold of 26 appears optimal. For testing in a @entity2414 clinic, a lower threshold has better predictive value.
