Screening evaluation of an ionized nanocrystalline XXXX dressing in chronic wound care.

@entity1 @entity575 @entity1066 @entity3179 @entity922
The successful topical treatment of chronic wounds requires adequate debridement, bacterial balance, and moisture balance. An ionized nanocrystalline @entity575 dressing was evaluated through an uncontrolled, prospective study of a case series of 29 @entity1 with a variety of chronic nonhealing wounds. The four arms of the study included nine @entity1 with foot @entity1066 , six @entity1 with @entity3179 , two @entity1 with pressure @entity1066 , and 12 @entity1 with miscellaneous wounds. All wounds were assessed for the usual signs of @entity922 , with most of these parameters being measured and recorded. Microbiologically, bacterial load was determined via quantitative biopsies and semi-quantitative swabs. In general, the results showed a marked clinical improvement for the majority of wounds treated with the dressing. Among improved parameters included decreased exudate and decreased purulence. The quantitative bacterial biopsies did not show any decrease in organism numbers, although the semi-quantitative swabs indicated a decrease in the wound surface bacterial loading. This was indicative of the dressing's ability to reduce surface bacteria and achieve an element of bacterial balance in the superficial dermal compartment. The proposed mechanism of action for this ionized nanocrystalline based dressing is through bacterial and moisture balance within the superficial wound space compartment.
