Autotransplantation of cryopreserved ovarian tissue after treatment for XXXX - the first Norwegian results.

@entity5 @entity1
INTRODUCTION: With increasing survival rates after treatment for @entity5 in prepubertal @entity1 and @entity1 of reproductive age, an increasing focus on quality of life has emerged. Both irradiation and cytotoxic drugs can be detrimental to future fertility, consequently several treatment alternatives have been developed to spare or restore fertility in young females diagnosed with @entity5 . One of these options is cryopreservation of ovarian tissue before treatment and autotransplantation at a later time. MATERIAL AND METHODS: We present the Norwegian experience after 11 years of practice with ovarian tissue cryopreservation. A total of 164 @entity1 have had ovarian tissue cryopreserved during the period 2004-2014. Fifteen @entity1 died during the observation period. Six @entity1 requested autotransplantation, which was performed in two @entity1 . RESULTS: Both @entity1 conceived, one spontaneously and one after assisted reproduction due to a concomitant male factor. The pregnancies were uneventful and they each gave birth to a healthy @entity1 . CONCLUSIONS: Cryopreservation with later autotransplantation of ovarian tissue should be offered to a selected group of young @entity1 with @entity5 .
