Enucleation for benign or low-grade malignant lesions of the pancreas: Single-center experience with 65 consecutive XXXX .

@entity1 @entity788 @entity6 @entity5 @entity260 @entity3472 @entity204
INTRODUCTION: Standard resection for benign and borderline @entity5 of the pancreas is associated with a substantial risk of postoperative morbidity and long-term functional impairment, whereas enucleation leads to less morbidity and preserves healthy parenchyma as well as pancreatic function. The aim of this study was to evaluate the postoperative clinical outcomes and long-term functional and oncologic results after pancreatic enucleation, and to compare the clinical results of laparoscopic and open enucleation. METHODS: From March 2005 to December 2013, 65 cases of enucleation of @entity5 in the pancreas were identified through a retrospective review of medical records. RESULTS: Most of the @entity1 were @entity1 (73.8 %), and the median age was 52.7  years (interquartile range 43.1-60.9  years). Median @entity5 size was 2.5  cm (interquartile range 1.6-3.8  cm). The most common indication for enucleation was @entity788 (24, 36.9%). A clinically relevant @entity3472 (International Study Group on Pancreatic Fistula grade B, C) was reported in 6 @entity1 (9.2%). The @entity1 with @entity5 of the pancreatic neck had more complications after enucleation than those with @entity5 at other locations (3/4, 75%). There were no differences of clinical outcomes between open and laparoscopic enucleation groups. At a median follow-up of 58.7  months there was one case of new-onset @entity6 , and there were no recurrences or @entity204 . CONCLUSION: Enucleation is a safe and effective procedure for the treatment of benign and borderline @entity788 . It preserves pancreatic function and is not associated with recurrence. The incidence of @entity260 , including @entity3472 , is acceptable. Laparoscopic enucleation seems to be a feasible and safe approach associated with favorable perioperative outcomes for the selected @entity1 .
