Studies on the effect of acute doses of XXXX ( @entity2918 inhibitor) during induced liver failure.

@entity4314 @entity1133 @entity19 @entity2918 @entity450 @entity383 @entity380 @entity1011 @entity3352
Fifty four male @entity19 were divided into 3 main groups. Control group (6 @entity19 ), @entity380 infected group (24 @entity19 ) and @entity4314 (CC14) treated group (24 @entity19 ). The last two groups were further subdivided into (4) subgroups (6 @entity19 /each). One of them served as a control while the other 3 subgroups received (0.75, 1.25 _ 2.5 mg/100g B.W.) of @entity3352 respectively. CC14 treated @entity19 were severely live 2 damaged than those infected by @entity383 . @entity3352 made the liver functions deteriorate. Schistosomiasis did not affect kidney functions while @entity1133 _ @entity1011 were elevated in CC14 treated group. @entity3352 led to more elevation of both. Histological studies of liver treated by CC14 revealed @entity450 , granular cytoplasm and cellular infiltration while schistosomiasis produced the classic granulomatous reaction. @entity3352 treatment led to distortion of hepatic cell arrangement as well as marked cellular infiltration and congestion. On the other hand, kidney treated with CC14 showed cellular infiltration around glomeruli, @entity3352 caused marked congestion and cellular infiltration. @entity380 infection did not produce any histological changes. All recorded changes could be attributed to the toxic effect of @entity3352 , inhibition of @entity2918 and weakness of the immunological cells of the liver.
