Levels of serum colony-stimulating factors (CSFs) in XXXX on long-term haemodialysis.

@entity1 @entity8 @entity1261 @entity1356 @entity310 @entity177 @entity6824 @entity2841
We measured the levels of colony-stimulating factors ( @entity1261 , @entity6824 and @entity2841 ) and several cytokines in paired sera obtained from 51 @entity1 (33 males and 18 females; mean age: 53 years) on long-term haemodialysis (HD). The mean pre-HD @entity1261 level was 22.7 +/- 21.7 pg/ml and the post-HD level was 40.3 +/- 54.4 pg/ml. The mean pre-HD @entity6824 level was 2.4 times higher than normal at 1287 +/- 380 U/ml, and it increased to 1644 +/- 456 U/ml after HD (r = 0.83). @entity2841 was not detectable in any of the serum samples. @entity1356 was detectable in 38 pre-HD sera at a mean level of 57.1 +/- 21.8 pg/ml, but was rarely detected after HD. @entity310 was not usually detected. When the CSF levels were divided by the product of the serum total protein concentration and body weight, the post-HD value for @entity1261 was almost always greater than the pre-HD value and there was an improved pre-post correlation (r = 0.69). In the transformed pairs of @entity6824 level, the post-HD value did not differ much from the pre-HD value, and a strong pre-post correlation was noted (r = 0.94). These results suggest that the serum @entity1261 level is not affected by @entity177 , although HD may induce an increase of @entity1261 . In the case of @entity6824 , however, @entity8 and/or excretion may increase the serum concentration, but it is not modulated by haemodialysis.(ABSTRACT TRUNCATED AT 250 WORDS)
