Early Vitrectomy for Spontaneous, Fundus-Obscuring XXXX .

@entity1 @entity1018 @entity548 @entity20699 @entity937 @entity1713 @entity989 @entity1020 @entity130
PURPOSE: To examine the visual outcomes of early intervention in the setting of fundus-obscuring @entity548 ( @entity548 ) presumed to be due to @entity20699 . DESIGN: Retrospective comparative case series. METHODS: All eyes that presented with a fundus-obscuring @entity548 , defined as vision of 20/400 or worse and requiring a B-scan at presentation from 2003 to 2013, were evaluated. Eyes with any history of @entity989 , @entity1020 , @entity130 , presentation greater than 2  weeks after onset of symptoms, or follow-up of less than 2  months were excluded. The main outcome measure studied was final best-corrected visual acuity (BCVA) as dependent on the time to surgery. RESULTS: Ninety-two eyes met inclusion criteria with a mean follow-up of 490  days. Initial BCVA was logMAR 2.218 (Snellen equivalent 20/3000-20/4000, range 20/400-light perception); final BCVA was 0.318 (Snellen equivalent of 20/40-20/50, range 20/20-light perception, P < .001). Fifty-six @entity1 (60.8%) had either a @entity937 or a @entity1713 . @entity1 who underwent surgery within 1  week had no significant improvement over all others; however, a significant improvement was found when comparing early vs delayed surgery groups (P  <  .05). There was a significantly increased risk of  developing a macula-off @entity1713 in @entity1 who did not undergo surgery within 1  week of presentation. CONCLUSIONS: Early surgical intervention results in similar visual outcomes compared to a conservative approach. However, early intervention significantly reduces the incidence of severe @entity1018 related to macula-involving @entity1713 . This study highlights the importance of close follow-up given the high risk of @entity1713 in fundus-obscuring @entity548 .
