Incidence of and mortality from XXXX in the United Kingdom. Steering Committee and members of the National Audit of @entity360 .

@entity1 @entity548 @entity5 @entity204 @entity360
OBJECTIVE: To describe the current epidemiology of @entity360 . DESIGN: Population based, unselected, multicentre, prospective survey. SETTING: 74 hospitals receiving emergency admissions in four health regions in the United Kingdom. SUBJECTS: 4185 cases of @entity360 in which @entity1 were aged over 16 years identified over four months. OUTCOME MEASURES: Incidence and mortality. RESULTS: The overall incidence of @entity360 in the United Kingdom is 103/100,000 adults per year. The incidence rises from 23 in those aged under 30 to 485 in those aged over 75. At all ages incidence in @entity1 was more than double that in @entity1 except in elderly @entity1 . 14% of the @entity548 occurred in inpatients already in hospital for some other reason. In 27% of cases (37% female, 19% male) @entity1 were aged over 80. Overall mortality was 14% (11% in emergency admissions and 33% in @entity548 in inpatients). In the emergency admissions, 65% of deaths in those aged under 80 were associated with @entity5 or organ failure at presentation. Mortality for @entity1 under 60 in the absence of @entity5 or organ failure at presentation was 0.8%. CONCLUSIONS: The incidence of @entity360 is twice that previously reported in England and similar to that reported in Scotland. The incidence increases appreciably with age. Although the proportion of elderly @entity1 continues to rise and mortality increases steeply with age, age standardised mortality is lower than in earlier studies. @entity204 occurred almost exclusively in very old @entity1 or those with severe comorbidity.
