Narrow band ultraviolet-B versus Goeckerman therapy for XXXX with and without @entity14028 : A retrospective study.

@entity1 @entity14028 @entity1569 @entity554
BACKGROUND: Narrow band ultraviolet-B (NB-UVB) is now one of the most widely used modalities in the treatment of @entity1569 . However, despite its high efficacy, conventional Goeckerman treatment has fallen out of favor in recent years and some institutions are now using NBUVB with coal tar as their regimen. OBJECTIVE: To evaluate the efficacy of NB-UVB, Goeckerman therapy and the effect of addition of @entity554 to the treatment regimen in the treatment of @entity1569 ,. @entity1 AND METHODS: A retrospective analysis of 65 @entity1 who underwent 81 courses of treatment in our department was undertaken. The efficacy of NB-UVB and Goeckerman therapy individually, and in combination with @entity14028 was assessed. Data were analysed to evaluate the contribution of @entity14028 to these modalities. RESULTS: PASI-75 responses in the NB-UVB, @entity554 + NB-UVB (re-NB), Goeckerman and @entity554 + Goeckerman (re-Goeckerman) groups were achieved for 12 of 31 @entity1 (39%), 13 of 21 @entity1 (62%), 15 of 17 @entity1 (88%) and 10 of 12 @entity1 , respectively. The addition of @entity14028 to both modalities reduced both the number of sessions and the cumulative ultraviolet-B dose delivered. LIMITATIONS: This is a retrospective study, the @entity1 were not randomized and the number of @entity1 in the treatment groups were dissimilar. CONCLUSION: Goeckerman therapy is more effective than NB-UVB phototherapy. Although the addition of @entity14028 to both NB-UVB and Goeckerman therapy did not contribute to treatment outcomes in terms of PASI-75 responses, it enabled a reduction in UV exposures and enhanced efficacy.
