[Peripheral blood stem cell collection with high dose XXXX ].

@entity1 @entity981 @entity1261 @entity706 @entity5 @entity2590 @entity3052 @entity2879 @entity1582 @entity1778
Peripheral blood stem cells (PBSC) were collected from 24 @entity1 who were treated with high dose @entity2879 . Studied @entity1 included one with @entity981 , 4 with @entity3052 ( @entity3052 ), 1 with @entity2590 , 13 with @entity706 , 1 with @entity5 , 2 with @entity1582 , and 4 with @entity5 . @entity2879 was infused at a dose of 500 mg/m2 for 4 days, followed by subcutaneous injection of recombinant @entity1 @entity1261 from the nadir of leukocyte. PBSC were collected by processing 15-20 liters of blood apheresis in the recovery phase of chemotherapy. In all @entity1 , the number of CFU-GM collected per aphereresis ranged from 0.01 to 59.4 x 10(5)/kg, and more than 5 x 10(5)/kg CFU-GM were collected in 19 of the @entity1 (73%). All @entity1778 @entity1 treated along with our protocols have remained in complete remission, but one @entity1 with @entity3052 relapsed within 1 month after the treatment. @entity706 @entity1 were assessable for antitumor effect, and complete response (CR) was observed in 2, partial response (PR) was 7, and no change (NC) in one @entity1 . Two @entity1 with @entity1582 were classified to be NC. Three of the 4 @entity1 with @entity5 were PR, and the other one was NC. Eleven @entity1 subsequently underwent PBSCT. The number of days required to achieve an absolute granulocyte count of 0.5 x 10(9)/l was 7 to 11 days, with a mean of 8.6.
