Efficacy of modified constraint-induced movement therapy in XXXX : a single-blinded randomized controlled trial.

@entity1 @entity64 @entity12335 @entity3140 @entity7595
OBJECTIVE: To determine efficacy of a modified constraint-induced movement therapy (mCIMT) protocol for @entity1 with @entity64 . DESIGN: Multiple-baseline, pre-post, single-blinded randomized controlled trial. SETTING: Outpatient clinic. @entity1 : Seventeen @entity1 who experienced @entity64 more than 1 year before study entry and who had @entity3140 and learned nonuse. INTERVENTION: Seven @entity1 participated in structured therapy sessions emphasizing more affected arm use in valued activities, 3 times a week for 10 weeks. Their less affected arms were also restrained 5d/wk for 5 hours (mCIMT). Four @entity1 received regular therapy with similar contact time to mCIMT. Six @entity1 received no therapy (control). MAIN OUTCOME MEASURES: The Fugl-Meyer Assessment of Motor Recovery ( @entity7595 ), Action Research Arm ( @entity12335 ) Test, and Motor Activity Log (MAL). RESULTS: The mCIMT @entity1 exhibited greater motor changes on the @entity7595 and @entity12335 (18.4, 11.4) than regular therapy (6.0, 7.1) or control (-2.9, -4.5). Statistical analyses showed significant differences in motor improvement on the @entity7595 (F(2,12)=11.2, P=.002) and the @entity12335 (F(2,12)=14.0, P=.001). Post hoc analyses showed that, when pretreatment motor differences are controlled, mCIMT resulted in substantially higher posttreatment @entity7595 and @entity12335 scores. Amount and quality of arm use, measured by the MAL, improved only in mCIMT @entity1 . CONCLUSIONS: mCIMT may be an efficacious method of improving function and use of the more affected arms of @entity64 @entity1 . Findings further affirm that repeated, task-specific practice is critical to reacquisition of function, whereas practice schedule intensity is less critical.
