Role of pleural lavage cytology before resection for primary XXXX .

@entity1 @entity1143 @entity5 @entity2 @entity3483 @entity420
OBJECTIVE: To investigate the role of pleural lavage cytology (PLC) in resection for primary @entity2 . SUMMARY BACKGROUND DATA: The prognostic significance of PLC before manipulation is still controversial. METHODS: Cytology of pleural lavage immediately after thoracotomy but before any manipulation of the lung was examined in 500 consecutive @entity1 with @entity2 with no @entity1143 who underwent pulmonary resections. Eighteen @entity1 who already had pleural dissemination were excluded from this study. RESULTS: Eighteen of 482 @entity1 (3.7%) had positive cytologic findings. The positivity of PLC was significantly correlated with histology, extension of @entity5 to pleura, and presence of lymphatic permeation or vascular involvement by @entity5 . Positive lavage findings were seen only in @entity420 . Because 6.3% of the @entity1 with @entity420 had positive cytologic findings, it is vital to perform PLC before curative resections for @entity2 , especially @entity420 . The 5-year survival rates of the @entity1 having negative and positive lavage findings were 52.9% and 14.6%, respectively. The prognosis of the @entity1 with positive lavage findings was as poor as that of the @entity1 with @entity5 and that of the @entity1 with @entity5 . CONCLUSIONS: Positive findings on PLC indicate exfoliation of @entity5 cells into the @entity1143 , which is an essential prognostic factor. In addition, we should regard positive cytologic findings as a subclinical @entity3483 that is pathologic stage T4.
