[ @entity2657 and changes of cerebral blood volume in XXXX with head injuries].

@entity1 @entity1545 @entity455 @entity2657 @entity4 @entity551
AIM: The pathogenesis of traumatic @entity4 remains unclear. The generally held view is that @entity4 is caused primarily by @entity455 and that @entity4 plays a relatively minor role in the swelling process. The goal of this study was to examine the roles of cerebral blood volume (CBV) and @entity4 in traumatic @entity4 . @entity1 AND METHODS: Both brain-tissue water and CBV were measured in 76 head-injured @entity1 , and the relative contribution of @entity4 and blood to total @entity4 was determined. Comparable measures of brain-tissue water were obtained in 30 healthy volunteers and CBV in seven volunteers. Brain @entity4 was measured using magnetic resonance imaging, implementing a new technique for accurate measurement of total tissue water. Measurements of CBV in subgroup of 31 head-injured @entity1 were based on consecutive measures of cerebral blood flow (CBF) obtained using stable xenon and calculation of mean transit time by dynamic computerized tomography scanning after a rapid bolus injection of iodinated contrast material. RESULTS: The mean (+/- standard deviation) percentage of swelling due to water was 9.37 +/- 8.7%, whereas that due to blood was -0.8 +/- 1.32%. CONCLUSION: The results of this study showed that @entity2657 is the major fluid component contributing to traumatic @entity4 . Moreover, CBV is reduced in proportion to @entity551 following severe @entity1545 .
