Quality of life, pulmonary function, and tomographic scan abnormalities after XXXX .

@entity1 @entity649 @entity393
BACKGROUND: @entity649 can produce a @entity393 with persistent sequelae. This study aimed to evaluate health-related quality of life (HRQL) in survivors of @entity649 compared with a healthy reference population and to determine the middle/long-term radiographic abnormalities and functional status, as well as their relation to observed HRQL, in these @entity1 . METHODS: This was a prospective study carried out in three ICUs. HRQL in @entity1 was determined with the Nottingham Health Profile immediately after @entity649 diagnosis and 6 months after diagnosis. @entity1 underwent complete respiratory function testing, chest CT scan study, and the 6-min walk test. RESULTS: Follow-up was conducted in 38 @entity1 with @entity649 . Survivors of @entity649 presented a poorer overall HRQL vs the general population, mainly because of lower scores in the dimensions related to mobility, energy, and social isolation. Limitations in daily life activities were documented in 40%. Respiratory function was altered in 67%, with a restrictive respiratory pattern in 58%. Radiologic study disclosed alterations in 76% (mainly reticular pattern). @entity1 were able to cover only 366 m (318-411 m) in the 6-min walk test and had a minimum pulse oximetry of 93% (90%-94%). A significant correlation was documented between the overall quality of life at first and at 6 months (r = 0.68, P < .01). CONCLUSIONS: Survivors of @entity649 after 6 months had a poorer HRQL than the healthy population and showed mild radiographic and functional involvement. Early HRQL study in these @entity1 enabled early detection of those who would present more long-term HRQL morbidity.
