Magnetic resonance angiography manifestations and prognostic significance in HIV-negative XXXX .

@entity1 @entity64 @entity1276 @entity1906 @entity465 @entity1188 @entity1317
OBJECTIVE: To evaluate the patterns, related factors and prognostic value of abnormal magnetic resonance angiography (MRA) in @entity1 @entity465 virus negative @entity1906 . MATERIALS AND METHODS: We performed a prospective study in @entity1 aged >14 years. Abnormality on MRA was correlated with clinical, laboratory and magnetic resonance imaging findings. Modified Barthel index was used to assess outcome at 6 months after inclusion. RESULTS: Of 101 @entity1 included, MRA was abnormal in 45 (44.6%). The distribution of MRA abnormality was classified as disseminated irregular calibres of intracranial arteries with or without reduction in distant branches (29.7%, pattern 1) and localised stenosis at the base of the brain (26.7%, pattern 2). In logistic regression analysis, pattern 2 was related to stage of the disease (P = 0.002), basal exudates (P = 0.03) and @entity1188 (P = 0.000), while pattern 1 was related to duration of disease (P = 0.050), @entity1276 (P = 0.032) and age (P = 0.002). Pattern 1 was also correlated with @entity1188 (P = 0.000), particularly @entity1188 in the tubercular zone (P = 0.035) in univariate analysis. MRA abnormality was associated with paradoxical worsening (P = 0.022) and poor prognosis in univariate analysis (P = 0.035). CONCLUSION: MRA abnormality is associated with @entity64 and poor outcomes. Although it indicates mild @entity1317 , pattern 1 MRA abnormality is nevertheless associated with @entity1188 and needs proper intervention.
