[Strategies in management of heart transplantation candidates with tachycardic XXXX anamnesis].

@entity1 @entity943 @entity1165 @entity737
We followed up 73 consecutive @entity1 with a history of syncopal @entity1165 on the waiting list for a heart transplant between 1st March 1992 and 15th September 1994 with the aim of evaluating the impact of @entity737 ( @entity737 ) on survival. On registration 60 @entity1 were considered fit enough to be ambulant whilst awaiting transplantation. 30 were given @entity737 therapy (group 1) and 30 were not (group 2). 13 @entity1 required inpatient supervision for @entity943 whilst awaiting transplantation, but received no @entity737 therapy (group 3). The 13 in- @entity1 were in a worse clinical state (NYHA) than the 30 out- @entity1 not given @entity737 (p < 0.05). With respect to all other clinical and hemodynamic characteristics all groups were comparable. Waiting time for transplantation was also comparable in all groups (n.s., log-rank method). @entity737 therapy resulted in a significant improvement of survival in these high-risk @entity1 prior to transplantation. Only 1 out of the 30 @entity737 @entity1 (group 2) and 5 out of the 13 in- @entity1 (group 3) (p < 0.05 log-rank method). During the waiting time group 3 @entity1 were hospitalised longest (p < 0.05), but there was a clear trend that also @entity737 @entity1 had to be hospitalised to an increased extent (n.s.). Cox multivariate regression analysis of this study population showed that the cardiac index (p = 0.001) and lack of @entity737 therapy (p = 0.035) were the only independent significant predictors of mortality on the waiting list. @entity737 therapy had no influence on mortality after transplantation (n.s. log-rank method).
