Characterization of Closed Head Impact Injury in XXXX .

@entity35 @entity131 @entity6075 @entity130
The @entity6075 ( @entity6075 ) @entity35 models are commonly used for studying the @entity131 . The impact parameters vary considerably among different laboratories, making the comparison of research findings difficult. In this work, numerical @entity6075 experiments were conducted to investigate the sensitivities of intracranial responses to various impact parameters (e.g., impact depth, velocity, and position; impactor diameter, material, and shape). A three-dimensional finite element @entity35 head model with anatomical details was subjected to impact loadings. Results revealed that impact depth and impactor shape were the two leading factors affecting intracranial responses. The influence of impactor diameter was region-specific and an increase in impactor diameter could substantially increase tissue strains in the region which located directly beneath the impactor. The lateral impact could induce higher strains in the brain than the central impact. An indentation depth instead of impact depth would be appropriate to characterize the influence of a large deformed rubber impactor. The experimentally observed velocity-dependent @entity130 could be attributed to the "overshoot" phenomenon. This work could be used to better design or compare @entity6075 experiments.
