Functional Visual Improvement After XXXX Surgery in Eyes With Age-Related Macular Degeneration: Results of the Ophthalmic Surgical Outcomes Data Project.

@entity1 @entity231 @entity13785
PURPOSE: To determine if @entity231 surgery on eyes with @entity13785 confers as much functional visual improvement as surgery on eyes without retinal pathology. METHODS: This is a retrospective analysis of 4924 @entity231 surgeries from the Veterans Healthcare Administration Ophthalmic Surgical Outcomes Data Project (OSOD). We included cases of eyes with @entity13785 that had both preoperative and postoperative NEI-VFQ-25 questionnaires submitted and compared their outcomes with controls without retinal pathology. We excluded @entity1 with other retinal pathologies (740 @entity1 ). The analyses compared changes in visual acuity and overall functional visual improvement and its subscales using t-tests, multivariate logistic regressions, and linear regression modeling. RESULTS: Preoperative and postoperative questionnaires were submitted by 58.3% of @entity13785 and 63.8% of no retinal pathology cases (controls). Analysis of overall score showed that @entity231 surgery on eyes with @entity13785 led to increased visual function (13.8    2.4 NEI-VFQ units, P < 0.0001); however, increases were significantly less when compared with controls (-6.4    2.9 NEI-VFQ units, P < 0.0001). Preoperative best-corrected visual acuity (preBCVA) in @entity13785 was predictive of postoperative visual function (r = -0.38, P < 0.0001). In controls, postoperative visual function was only weakly associated with preBCVA (r = -0.075, P = 0.0002). @entity1 with @entity13785 with vision of 20/40 or better had overall outcomes similar to controls (-2.2    4.7 NEI-VFQ units, P = 0.37). CONCLUSIONS: @entity231 surgery on eyes with @entity13785 offers an increase in functional visual improvement; however, the amount of benefit is associated with the eye's preBCVA. For eyes with preBCVA of 20/40 or greater, the improvement is similar to that of @entity1 without retinal pathology. However, if preBCVA is less than 20/40, the amount of improvement was shown to be significantly less and decreased with decreasing preBCVA.
