Management of XXXX : seventeen years' experience.

@entity1 @entity3256 @entity794 @entity281 @entity204 @entity734 @entity16859 @entity884
@entity884 remains a serious illness with a high mortality. In more than 75% of 417 @entity1 , the @entity281 was due to gram-positive microorganisms. The non- @entity734 @entity1 (33%) were elderly and debilitated with advanced illness that preceded the @entity884 . The @entity734 @entity1 (67%) were young and were infected with multiple kinds of microorganisms. The blood cultures grew strains of @entity794 resistant to @entity3256 and @entity16859 in a majority of @entity1 . Gram-negative microorganisms and fungi were cultured almost exclusively from samples from the @entity734 @entity1 . The high mortality among the non- @entity734 @entity1 (28%) was related to their advanced age and debilitating illness. The high mortality among the @entity734 @entity1 (21%) was related to the complex bacteriology of their infections and the severe anatomical disruption of the valvular complexes of the heart. When cured of their disease after treatment with intravenously administered antibiotics or a valve procedure or both, their long-term survival was related to whether or not they abstained from their habit. If the @entity1 abstained from the use of drugs, the chances of survival were good; if not, @entity204 invariably ensued. This experience strongly supports our contention that if a @entity1 returns to the use of drugs and reinfects the valve after initial cure, a second valve operation is contraindicated.
