A positive correlation between neutrophils in regional lymph nodes and progression of XXXX .

@entity1 @entity32 @entity5 @entity1600 @entity356
Backgrond/Aim: Recent evidence indicates that @entity32 is a hallmark of @entity5 . @entity5 -associated neutrophils (TANs) contribute to @entity5 invasion. However, whether TANs and @entity1600 are related is unknown. Intranodal lymphatic vessel density (LVD) is significantly correlated with @entity5 progression, @entity1600 in @entity356 . Herein, we investigated the effects of TANs in regional lymph nodes. MATERIALS AND METHODS: We investigated the association of the density of TANs in regional lymph nodes with clinicopathological features by immunohistochemistry. Furthermore, we examined the prognostic value of TANs in lymph nodes. RESULTS: The number of TANs in regional lymph nodes was positively correlated with intranodal LVD and micrometastases. @entity1 with higher cluster of differentiation 15(+) TAN counts had significantly poorer prognosis than those with lower counts. CONCLUSION: Our results suggest that TANs in regional lymph nodes promote the invasion of lymph nodes by @entity5 cells via augmentation of lymphangiogenesis and thereby contribute to @entity5 progression.
