MR-detected changes in liver fat, abdominal fat, and vertebral bone marrow fat after a four-week calorie restriction in XXXX @entity1 .

@entity1 @entity1386 @entity28
PURPOSE: To determine changes in the bone marrow fat fraction (BMFF) in @entity28 after dietary intervention in comparison with changes in abdominal fat, liver fat, and serum lipids. MATERIALS AND METHODS: Twenty @entity28 (BMI 34.92        3.8 kg/m(2) ) @entity1 participated in a 4-week dietary intervention of 800 kcal/d plus additional vegetables. They underwent anthropometric and blood value measurements before and after the intervention. Abdominal 3T MRI was performed to measure changes in @entity1386 ( @entity1386 ) and visceral adipose tissue (VAT) volume and single-voxel magnetic resonance spectroscopy (MRS) to measure fat content changes in the liver and L5 vertebral body. RESULTS: The greatest relative change after dietary intervention was found in the liver (-40.3%), followed by VAT volume (-15.1%), serum lipids (-12.6 to -14.5%), and @entity1386 volume (-8.5%). There were no statistically significant changes in BMFF after dietary intervention (P   =   0.39), but absolute changes in the BMFF were positively associated with @entity1386 volume (r   =   0.489) and negatively associated with nonadipose tissue volume (r   =   -0.493) before dietary intervention. CONCLUSION: Bone marrow behaves differently compared to @entity1386 volume, VAT volume, liver fat, and serum lipids after a 4-week dietary intervention in @entity28 and BMFF changes depend on abdominal tissue volumes before intervention. J. Magn. Reson. Imaging 2015.
