T-cell dependent and T-cell independent immune response in normal and in with Litomosoides carinii infected XXXX @entity35 .

@entity558 @entity308 @entity2708 @entity281 @entity35
The immune responses to SRBC and @entity558 were examined in immunized and non-immunized inbred @entity2708 @entity35 at different times after an infection with Litomosoides carinii. During the infection, the T-cell dependent immune response to SRBC was significantly suppressed in non-immunized animals as compared to non infected controls. In contrast, after immunization with SRBC the antibody levels of infected animals were significantly higher in three of five events. At the onset of patency the response to SRBC was significantly depressed transiently in immunized animals. A corresponding @entity308 could be provoked by injections of isolated microfilariae as well as by FCS in immunized animals, @entity281 . The level of the antibodies was dependent on the density of microfilariae in the peripheral blood. The T-cell independent response to @entity558 was equal in non-immunized infected animals as in controls. After immunization with @entity558 during prepatency and at onset of patency a distinct but commensurate reaction was observed. Only after immunization at the peak of patency, the immune response of infected animals was significantly suppressed. In general, the antibody levels to @entity558 were not influenced by the microfilaremia.
