Total paracentesis with dextran 40 vs diuretics in the treatment of @entity843 in XXXX : a randomized controlled study.

@entity1 @entity82 @entity1369 @entity843 @entity916 @entity99
The aim of the current study was to compare total paracentesis associated with dextran-40 infusion with diuretics in the treatment of tense @entity843 in @entity1 with @entity82 . Eighty @entity1 were randomly allocated to two groups: 40 @entity1 were treated with paracentesis plus dextran-40 infusion (8 g per liter of ascitic fluid removed), and 40 @entity1 with diuretics. After treatment @entity1 were discharged with diuretics, and @entity1 developing tense @entity843 during follow up (54 +/- 4 weeks) were treated according to their initial schedule. Paracentesis was more effective than diuretics in mobilizing the ascitic fluid. The incidence of complications was significantly higher (p < 0.05) in the diuretic group (38%) than in the paracentesis group (15%). This difference was mainly due to a higher incidence of @entity99 in the former group (30% vs. 2.5%). A significantly higher incidence of @entity99 was also observed in the diuretic group during the follow-up readmissions for @entity843 recurrence. There were no significant differences between the two treatment groups in the probability of survival after inclusion. Plasma @entity916 activity and plasma @entity1369 concentration measured before and 2 and 6 days after paracentesis in 20 randomly selected @entity1 increased significantly (p < 0.05) (baseline values: 5.3 +/- 1.4 ng.ml-1.h-1 and 63 +/- 21 ng/dl; 48 h after paracentesis: 11.7 +/- 3.9 ng.ml-1.h-1 and 99 +/- 31 ng/dl; 6 days after paracentesis: 10.9 +/- 3 ng.ml-1.h-1 and 110 +/- 27 ng/dl).(ABSTRACT TRUNCATED AT 250 WORDS)
