XXXX before antidepressant therapy in @entity308 .

@entity1 @entity308 @entity915 @entity750 @entity663 @entity250
BACKGROUND: Decreased sexual interest and function both occur as a consequence of antidepressant medication use, and are especially associated with @entity750 reuptake inhibitors (SRIs). However, few investigators have reported the base rate for disturbances in sexual desire, arousal and orgasm or ejaculation in @entity1 with @entity308 ( @entity308 ) prior to antidepressant treatment. The purpose of this report is to define the frequency of @entity250 ( @entity250 ) in 134 @entity1 with @entity308 and examine the relationship between @entity250 and demographic, clinical and personality variables. METHOD: A consecutive series of 55 male and 79 female @entity308 @entity1 diagnosed by @entity915 -DSM IV assessment completed a series of psychometric measures including a Sexual Function Questionnaire, which asked about change in sexual interest and function as well as sexual activity during the preceding month. RESULTS: Only 50% of @entity1 and 75% of @entity1 reported sexual activity during the preceding month. Over 40% of @entity1 and 50% of @entity1 reported decreased sexual interest. Reduced levels of arousal were more common in both @entity1 and @entity1 (40-50%) than ejaculatory or orgasm difficulties (15-20%). In @entity1 , problems with arousal and orgasm correlated with higher @entity663 and lower extraversion. There was no relationship between @entity250 and personality measures in @entity1 . While age at onset of @entity308 and number of prior episodes showed a modest correlation with @entity250 measures, there were no correlations with severity of @entity308 or specific symptoms clusters. LIMITATIONS AND CONCLUSIONS: Although limited by a relatively small sample of drug free @entity1 with @entity308 , and by the absence of a non-depressed comparison sample, these results emphasize the importance of factors beyond specific drug effects in the assessment of antidepressant related @entity250 .
