One-year prognosis after XXXX and the failure of the ROSE decision instrument to predict one-year adverse events.

@entity1 @entity64 @entity943 @entity548 @entity510 @entity341 @entity1163 @entity358 @entity583 @entity204
STUDY OBJECTIVE: We investigate the incidence of adverse events at 1 year in the cohort of @entity341 ( @entity341 ) @entity1163 @entity1 enrolled in the original Risk Stratification of @entity1163 in the Emergency Department (ROSE) study, the time to adverse event, and the test performance of the ROSE decision instrument to detect events at 1 year. METHODS: This report details the 1-year follow-up of adult @entity1163 @entity1 presenting to the @entity341 who were enrolled into the ROSE study, a single-center, prospective, observational cohort study. The primary endpoint was the combination of serious outcome and all-cause @entity204 at 1 year. Serious outcome encompassed @entity583 , life-threatening @entity943 , need for pacemaker/implantable defibrillator, @entity358 , @entity64 , @entity510 , and interventional procedure or @entity548 requiring blood transfusion. Secondary endpoints were all-cause @entity204 and cardiovascular serious outcome at 1 year. RESULTS: One thousand forty-three @entity1 were available for analysis; 162 @entity1 (15.5%) had a primary outcome. Twenty-eight (17%) of these were within 24 hours, 56 (35%) were within 1 week, and 78 (48%) were within 1 month. The remaining 84 (52%) outcomes occurred between months 2 and 12. At 1 year, 71 (6.8%) @entity1 had died and 76 (7.3%) had a cardiovascular serious outcome. The sensitivity and specificity of the ROSE decision instrument for 1-year serious outcome and all-cause @entity204 were, respectively, 71.6% (95% confidence interval [CI] 63.9% to 78.3%) and 71.1% (95% CI 67.9% to 74.0%); for 1-year all-cause @entity204 , 76.1% (95% CI 64.2% to 85.1%) and 67.4% (95% CI 64.3% to 70.3%); and for 1-year cardiovascular serious outcome, 75.0% (95% CI 63.5% to 83.9%) and 67.5% (95% CI 64.5% to 70.5%). CONCLUSION: The proportion of @entity1 with serious outcome and all-cause @entity204 1 year after @entity1163 is similar to that reported in recent international @entity1163 studies. We have defined the proportion of @entity1 with cardiovascular serious outcome at 1 year and have shown that most events occurred in the first month, with decreased frequency of events observed after that time especially marked for cardiovascular serious outcome. More than 50% of the outcomes observed, however, occurred after the first month. The ROSE decision instrument does not perform well at predicting 1-year outcome of @entity1163 @entity1 .
