Comparison of cellulose XXXX polymer and electrolytic detachable coils for treatment of @entity235 aneurysmal models.

@entity1713 @entity235 @entity1756 @entity598 @entity887 @entity439 @entity715 @entity850 @entity1211 @entity438
OBJECTIVE: @entity1713 ( @entity1713 ) have been the main embolic materials for @entity438 . Liquid aneurysmal embolic materials represented by cellulose @entity598 polymer (CAP) are still in controversy. In this research, the embolization results and pathological reactions after embolization of @entity235 aneurysmal models with @entity1713 or CAP were observed and compared. METHODS: The @entity235 aneurysmal models constructed by anastomosis of @entity1211 were randomly grouped. The @entity439 were respectively occluded with CAP and electrolytic detachable coils that was named by Wu electrolytic detachable coil (WEDC) and made by us. Angiogram follow-ups were performed at 24-hour, 2-week, and 2-month after embolization. The @entity439 were dissected in each stage for light microscopic, electron microscopic, and histochemical research. RESULTS: The effect of embolization was significantly better with WEDC than that with CAP (chi2 = 5. 56, P < 0.05). Post-embolized complications such as @entity1756 and @entity850 of parent arteries could only be found in CAP group. Pathological research showed that CAP mass could packed the @entity439 more densely than coils. Acute chemical damage of aneurysmal wall and inflammatory cell infiltration was prominently found in early stage after @entity887 . Organization of @entity715 inside @entity439 and formation of endothelial tissue over the orifices of aneurysmal necks could be found in both groups 2 months after embolization. But parts of coils might be exposed outside endothelial layer. CONCLUSIONS: @entity1713 are still the most safe, efficient, and reliable instruments to embolize @entity439 . CAP should be improved further to solve the problem of strong chemical corrosion and difficulty in control before it is widely used.
