Cell-based therapy of chronic XXXX .

@entity1 @entity63 @entity16 @entity2103 @entity191 @entity7995 @entity1463 @entity1939 @entity179 @entity302 @entity195 @entity15 @entity5013
The traditional methods of pharmacotherapy of the @entity179 do not frequently allow one to achieve the desired clinical effect. The fundamentally new approach for the treatment of severe @entity16 is provided by the methods of biological medicine, in particular, transplantation of a complex of fetal tissues. Cell-based therapy was used to treat @entity1 with @entity15 ; ante-, intra- and postnatal lesions; consequences of hemorrhagic and @entity63 apoplexies; @entity5013 of @entity2103 ; @entity1463 ; @entity191 ; @entity195 ; @entity302 and other types of pathologic process. The source material for obtaining a suspension of cells was the fetuses of allogenic origin. The suspension of brain cells in amounts of up to 1.5 x 10(8) cells and vitality not less than 40% was administered to the @entity1 into liquor spaces using the method of endolumbar puncture. The total number of transplantations was 1900. Practically in all the cases FT was tolerated well. Positive clinical and immunologic changes were observed in the majority of the @entity1 , thus, remission induction (in the @entity1 with the progressive course of @entity15 ) for a period over 12 months was registered in 87.5% of the cases. Noteworthy that considerable changes were observed in immunograms: depression of antibody levels to brain-specific proteins, native and denatured DNA; quantitative and qualitative improvement of lymphocyte subpopulation indices, positive changes in the immunoregulatory index. Clinically, in 69% of the cases there was an improvement in more than one @entity16 and a change in the values of the Kurtzke scale towards a decrease by 2-3 points. The conduct of cell therapy with the @entity15 @entity1 under the acute process conditions after liquorosorption allowed the arresting of clinical manifestations and the creation of preconditions for further restoration. The retrobulbar transplantations provided a quick arrest of the @entity7995 clinical symptoms and in one case an almost complete restoration of vision in the @entity1 with @entity1939 ( @entity1939 ). The remission duration has a marked direct dependence on the number of courses of endolumbar transplantations. Thus, the method of cell therapy with the use of @entity1 tissue transplantations is safe and can be used for different @entity179 of the central nervous system. The high efficacy of the method suggests the possibility and necessity of using this method as an alternative of classical pharmacological therapy. An important element of cell therapy is the control after the state of the @entity1 's immunity system.
