Methodology of Motor Evoked Potentials in a XXXX Model.

@entity1 @entity2749 @entity451 @entity63 @entity95 @entity1957 @entity2759 @entity1875 @entity86 @entity5161 @entity551 @entity386
UNASSIGNED: @entity2759 ( @entity2759 ) is a devastating complication of aortic operations. Neuromonitoring using @entity1957 ( @entity1957 ) is a sensitive modality to detect @entity2759 in @entity1 . We describe a leporine @entity2759 model using @entity1957 to test pharmaceutical therapeutics and other neuroprotective adjuncts. In 80 @entity95 , methods to obtain @entity1957 in normotensive and @entity63 @entity95 were developed. The effects of @entity5161 , @entity1875 , @entity386 , and @entity551 on lower extremity @entity1957 were studied. Lower extremity @entity1957 disappear upon @entity2759 induction in 78 of 78 (100  %) @entity95 . Prior to @entity2759 induction and during @entity2749 , lower extremity @entity1957 were lost in all (100  %) and upper extremity @entity1957 in one (25  %). @entity5161 was used in four experiments, with loss of lower extremity @entity1957 in all four (100  %) and loss of upper extremity @entity1957 in zero. With @entity1875 upper extremity, @entity1957 were obtainable in 80 of 80 @entity95 (100  %) and lower extremity @entity1957 in 78 of 80 @entity95 (97.5  %) prior to @entity2759 induction. The presence of these lower extremity @entity1957 prior to @entity2759 induction was not correlated with @entity551 . Disappearance of @entity1957 occurred in all 45 @entity95 with @entity86 . @entity1957 in the leporine model correlate closely with @entity451 . @entity1957 are influenced by inhaled anesthetics and @entity386 but not by @entity551 alone. @entity1875 anesthesia provides reliable @entity1957 . This study provides the basis for a reproducible model of @entity2759 to be used for novel therapeutic drug development.
