XXXX in Kweneng District, Botswana, A prevalence survey and a controlled treatment trial.

@entity5293 @entity1 @entity417 @entity3321 @entity281 @entity17447
Stool specimens from a sample of schoolchildren at six schools in Kweneng District were examined for @entity5293 , using the brine flotation method. @entity17447 was the only hookworm identified. The western part of the District forms part of the Kalahari Desert, and in four villages here 90%, 88%, 88% and 86% of the @entity1 were infected. In two villages in the eastern non-desert part, only 13% and 9% were infected. @entity281 were light. There was no significant correlation between severity of @entity281 and @entity417 . In one school (228 pupils; 86% infected with hookworm), half the @entity1 were treated with @entity3321 (0.1 ml/kg, maximum 5 ml) and the other half with placebo. Two weeks after treatment the prevalence of @entity281 were 28% and 75% respectively (p less than 0.001), and five months after treatment 51% and 69% (p less than 0.05). Measured over the five-month period there were no significant changes in haemoglobin and nutritional status (weight/height). Based on the results of the survey, a hookworm mass treatment programme was not recommended.
