Neonatal coxsackievirus B1 infection associated with severe XXXX : report of three cases.

@entity1 @entity882 @entity879 @entity5422 @entity1576 @entity810 @entity99 @entity2401
Coxsackievirus B infection may cause @entity879 in the neonate. In most reports the prominent symptoms have been recognized as @entity2401 and @entity5422 , and a majority were caused by type B2 to B5. Coxsackie B1 was a rare cause. From December 1993 to April 1994 three newborns were admitted to this Hospital with similar presentations of acute @entity99 and @entity882 . Coxsackie B1 virus was isolated from all at one or two sites including rectal swab, throat swab and urine. One fatal case had had symptoms from birth; the disease progressed rapidly initially with a strikingly high liver enzyme; @entity1576 was noted; @entity810 then happened later and the baby expired in two weeks. The other two @entity1 survived, though one also had severe fulminant @entity99 . In that case onset of the disease was late at 28 days old. The other's clinical course was mild from the beginning. @entity2401 or central nervous system involvement were apparently not the significant presentations. Because the three babies all came from areas near this city (Chung-Ho and Pan-Chiao), attention should be drawn to the prevalence of coxsackie B1 virus infection in the total community.
