Linseed based saliva substitutes and their effect on mineral dissolution of predemineralized XXXX dentin in vitro.

@entity6546 @entity1391 @entity460 @entity1388 @entity291
OBJECTIVES: Polymers used in saliva substitutes might inhibit remineralization. The present study evaluated the effects of various @entity460 , @entity1391 , and @entity1388 concentrations of linseed based solutions on the mineral loss of predemineralized @entity291 dentin in vitro. METHODS: Dentin specimens were prepared, embedded and polished. The specimens were demineralized (pH 5.6; 6 d; 37 degrees C) and half of each sample was covered with nail varnish. Subsequently, the specimens (n=10) were exposed to 14 linseed based solutions ( @entity460 0-1.1 mM; @entity1391 0-7.7 mM, @entity1388 0-0.03 mM) at pH 5.5 and 6.5 as well as to Salinum for 14 days (37 degrees C). The differences in mineral loss (DeltaDeltaZ) between the values prior to and after storage in the solutions were evaluated from microradiographs of thin sections. RESULTS: After the exposure to the various solutions decreased mineral contents compared to those after demineralization could be observed (p<0.05; paired t-test) whereas for the specimens stored in solution with the highest @entity460 and @entity1391 concentration no significant change in mineral loss could be evaluated (p>0.05). Salinum induced a significantly greater mineral loss compared to the equivalent saturated solution (p<0.05; ANOVA, Bonferroni). The general linear model revealed a significant dependency for DeltaDeltaZ on ' @entity1391 ' (p=0.000) and ' @entity1388 ' (p=0.001), but not on ' @entity460 ' (p=0.397) and 'pH' (p=0.368). CONCLUSIONS: The addition of @entity460 , @entity6546 , and @entity1388 seems to have a positive effect on the remineralizing qualities of linseed based saliva substitutes.
