[Value of local radiotherapy in treatment of osseous metastases, pathological XXXX and spinal cord compression].

@entity1 @entity174 @entity5 @entity16 @entity158
Local radiotherapy plays an important and responsible role in the management of bone metastases. The valence will be described according to the different treatment objectives in the sense of @entity158 relief, remineralization and cord decompression. Radiotherapy schedules, aimed at the @entity158 , need to take into consideration life expectancy. @entity1 with a reduced life expectancy could have a good high chance of achieving @entity158 relief with a single dose of 8 Gy. @entity1 with a solitary metastasis, @entity1 with a longer life expectancy and @entity1 with a pathological @entity174 should be treated with 'curative' irradiation doses, aimed at killing the maximum number of @entity5 cells. In addition to @entity158 relief, remineralization is also an important treatment goal. Conventional radiotherapy with doses of 40-50 Gy resulted in @entity158 relief in 70-100% and in remineralization in 60-80% of the @entity1 . Remineralization could not be accelerated by short-course fractionation courses, but resulted in @entity158 relief. Short-course fractionation schedules are not indicated as a 'standard' treatment in the vertebral column. Surgery is the treatment of choice for immediate cord decompression and stabilization of a pathological @entity174 . Radiotherapy alone could decrease @entity16 and is suitable for @entity1 with gradual onset and progression of symptoms, no spinal instability and lesions of the cauda equina.
