Renal histological changes secondary to XXXX .

@entity1 @entity3551 @entity8 @entity32 @entity45 @entity4145
The treatment of @entity1 with apparent @entity4145 is controversial. In an asymptomatic @entity1 or @entity1 the decision to recommend pyeloplasty usually is based on interpretation of the renal scan. We retrospectively analyzed the renal biopsy obtained during pyeloplasty in 55 @entity1 . Histological changes were compared to the differential renal function revealed on the preoperative renal scan. Histological changes were graded on a scale of I to V; I--normal, II--mild dilatation of the collecting tubules or Bowman's space and III to V--progressively severe changes of obstructive @entity3551 , including reduced glomerular number, @entity8 , @entity45 and @entity32 . @entity1 age ranged from 4 days to 19 years (mean 4.8 years). Mean differential function according to histological grade was I--49%, II--43%, III--42%, IV--30% and V--25%. Of 33 @entity1 with a differential function of 40% or greater 26 (79%) had a grade I or II biopsy, while 21% had a more significant alteration in renal histology. In contrast when the differential function was less than 40% 6 of 18 @entity1 (33%) had grade I or II disease on biopsy. In conclusion, in approximately 25% of @entity1 with @entity4145 there is a disparity between preoperative differential renal function computed during diuretic renography and renal biopsy.
