The Effectiveness of Additional Treatment Modalities after the Failure of Recanalization by Thrombectomy Alone in XXXX .

@entity1 @entity64 @entity66 @entity432 @entity731 @entity385
OBJECTIVE: @entity432 ( @entity432 ) is a devastating disease with a high mortality rate. One of the most important factors affecting favorable clinical outcome is early recanalization. Mechanical thrombectomy is an emerging treatment strategy for achieving a high recanalization rates. However, thrombectomy alone can be insufficient to complete recanalization, especially for @entity64 involving large artery @entity66 . The purpose of this study is to investigate the safety and efficacy of mechanical thrombectomy in @entity432 . METHODS: Fourteen consecutive @entity1 with @entity432 were treated with mechanical thrombectomy. Additional multimodal treatments were intra-arterial (IA) thrombolysis, balloon angioplasty, or permanent stent placement. Recanalization by thrombectomy alone and multimodal treatments were assessed by the Thrombolysis in @entity385 (TICI) score. Clinical outcome was determined using the National Institutes of Health @entity64 Scale (NIHSS) at 7 days and the modified Rankin Scale (mRS) at 3 months. RESULTS: Thrombectomy alone and multimodal treatments were performed in 10 @entity1 (71.4%) and 4 @entity1 (28.6%), respectively. Successful recanalization (TICI 2b-3) was achieved in 11 (78.6%). Among these 11 @entity1 , 3 (27.3%) underwent multimodal treatment due to underlying @entity731 . Ten (71.4%) of the 14 showed NIHSS score improvement of >10. Overall mortality was 3 (21.4%) of 14. CONCLUSION: We suggest that mechanical thrombectomy is safe and effective for improving recanalization rates in @entity432 , with low complication rates. Also, in carefully selected @entity1 after the failure of recanalization by thrombectomy alone, additional multimodal treatment such as IA thrombolysis, balloons, or stents can be needed to achieve successful recanalization.
