Clinical-histopathologic concordance of XXXX at the Manuel Velasco Su  rez National Institute of Neurology and Neurosurgery in Mexico City.

@entity1 @entity3002 @entity5 @entity11809
CONTEXT: When making a diagnosis, the main purpose of clinicians should not be to achieve certainty, but to decrease diagnostic uncertainty in order to make optimal therapeutic decisions. Diagnostic concordance is an essential characteristic if a measurement is to be considered scientific. In the case of @entity11809 ( @entity3002 ), one of the most accurate diagnostic tests is magnetic resonance imaging. However, histopathologic analyses are essential, because they refine the diagnosis, benefit the @entity1 , and improve our understanding of the disease. By determining the clinical-histopathologic correlation of @entity3002 in one of the main neurologic centers in Mexico, we sought to project reliable morbidity and/or mortality statistics. OBJECTIVE: To assess clinical and histopathologic diagnostic agreement in cases involving @entity3002 admitted to the Manuel Velasco Su  rez National Institute of Neurology and Neurosurgery between 1990 and 1999. DESIGN: Cross-sectional diagnostic concordance study, including all clinical hospital records of @entity1 with histopathologically diagnosed @entity3002 , classified according to World Health Organization criteria. RESULTS: Among 2041 @entity3002 cases, the 3 most frequent types were those affecting the neuroepithelial tissue (32.9%), @entity5 of the sellar region (29.2%), and @entity5 of the meninges (25.6%). We found that, overall, clinical-histopathologic concordance for these 3 categories was substantial and statistically significant. CONCLUSIONS: @entity11809 constitute a heterogeneous group of @entity5 . In the present study, clinical diagnoses substantially agreed with pathologic diagnoses. The a priori clinical diagnosis allowed prompt treatment even before diagnostic confirmation by histopathologic analysis, which is the best way to confirm, clarify, and correct a diagnosis.
