The effects of XXXX on @entity63 @entity5721 in @entity1 undergoing arthroscopy under spinal anesthesia.

@entity1 @entity66 @entity5721 @entity63 @entity26 @entity3652 @entity2586 @entity1341 @entity1234 @entity6948 @entity1865
OBJECTIVE: @entity63 and @entity5721 due to tourniquet application during arthroscopy is a well known problem. This study aimed to compare the effects of @entity6948 and @entity3652 on hemodynamic and respiratory variables and on @entity66 ( @entity66 ), @entity66 ( @entity66 ) and @entity1234 ( @entity1865 ) as markers of @entity63 - @entity5721 . MATERIALS AND METHODS: This study was approved by a local ethics committee. The study was performed on @entity1 undergoing arthroscopic operation under spinal anesthesia. Thirty @entity1 were randomized into two groups: Group D ( @entity6948 ; n=15) and Group K ( @entity3652 ; n=15). Spinal anesthesia at the @entity2586 level was achieved using a 25G spinal needle with hyperbaric @entity1341 at a dose of 12-15 mg in all @entity1 . In Group D, @entity1 were sedated with @entity6948 at a dose of 0.3-0.5  g/kg/h, while Group K received @entity3652 at a dose of 1-1.5 mg/kg/h. Hemodynamic parameters, @entity26 saturation, Ramsey sedation scale (RSS), and @entity66 , @entity66 , and @entity1865 levels were recorded. RESULTS: Demographic parameters, @entity66 , @entity66 and @entity1865 levels were similar between groups. In Group K, the @entity66 levels after tourniquet removal were significantly lower than at baseline and during the use of the tourniquet. Preoperative hemodynamic and respiratory variables were similar in both groups. Blood pressure values were decreased compared to baseline but these decreases were not statistically significant. CONCLUSION: In @entity1 undergoing arthroscopy under spinal anesthesia, @entity6948 had effects similar to @entity3652 , led to insignificant alterations in hemodynamic and respiratory variables during surgery and had comparable effects on @entity63 - @entity5721 . Thus, we think that @entity6948 can be a safe alternative to @entity3652 as an intraoperative sedative.
