[Clinical evaluation of XXXX by intravenous drip infusion for @entity281 in the field of internal medicine].

@entity1 @entity5134 @entity295 @entity82 @entity5693 @entity6 @entity55 @entity548 @entity565 @entity1067 @entity5 @entity4509 @entity1503 @entity281 @entity1778 @entity1729 @entity1576 @entity15126 @entity413 @entity293
@entity4509 ( @entity4509 ) by intravenous drip infusion was given to @entity1 with @entity281 in the field of internal medicine and the results were followings: AMK was administered to 19 @entity1 . Diagnosis included @entity295 or suspected @entity295 (11 cases), @entity55 (2 cases), chronic @entity1729 (3 cases) and @entity293 (3 cases). Underlying disease included @entity1503 (13 cases), @entity82 (1 case), chronic @entity1576 (1 case), @entity6 (1 case), @entity5693 and @entity565 (1 case) and @entity1067 (1 case). Nineteen episodes responded to single therapy (2 cases) or combined therapy with other antibiotics (17 cases). AMK by intravenous drip infusion (dissolved in not less than 100 ml of saline or @entity413 ) was administered at the dose of 200 mg/day to 600 mg/day divided into 2 or 3 times, over 1 hour to 2 hours. The mean duration of therapy was 10 days and the mean total dose was 4.3 g. Clinical effects: Excellent in 7 cases, good in 7 cases, fair in 3 cases and poor in 2 cases, and efficacy rate was 74%. Bacteriological effects: Disappeared in 3 cases, partly disappeared and unchanged in 3 cases, superinfection in 1 case and newly appeared in 1 case. Four strains out of 7 cases of which were detected the causative bacteria were disappeared. GM resistant bacteria ( @entity5134 in 2 strains and @entity15126 in 1 strain) were disappeared by the administration of AMK, also some clinical symptoms and signs were improved. No side effects and no abnormalities in laboratory findings were noted in any cases attributed to AMK. In conclusion, high efficacy rate was obtained without any side effects, intravenous drip infusion of AMK seemed to be useful for @entity281 in @entity1 with @entity548 tendency (e.g. @entity1778 ) or @entity5 .
