Prevention of a XXXX by Biological Mesh Reinforcement.

@entity1 @entity23 @entity3976 @entity547
INTRODUCTION: In the field of @entity547 prevention, the prophylactic mesh-reinforcement of stoma-sites is one of the most controversially discussed issues. The incidence of @entity547 in the literature reported to be up to 48.1% after end colostomy and up to 30.8% after loop of colostomy, but still remains uncertain due to diagnostic variety of clinical or radiological methods, heterogeneous @entity1 groups and variable follow-up intervals. Anyway, the published data regarding the use of synthetic or bio-prostethic meshes in the prevention of @entity547 at the primary operation are very scarce. METHODS: A literature search of the Medline database in terms of biological prophylactic mesh implantation in stoma creation identified six systematic reviews, two @entity23 ( @entity23 ), two case-controlled studies, and one technical report. RESULTS: In a systematic review focusing on the prevention of @entity547 including only RCTs encompassing one @entity23 using bio-prosthetic mesh the incidence of @entity3976 was 12.5% compared to 53% in the control group (p   <   0.0001). In one @entity23 and two case-control studies, respectively, there was a significant smaller incidence of @entity3976 as well as a similar complication rate compared to the control group. Only in one @entity23 , no significant difference regarding the incidence of @entity547 was reported with comparable complication rates. CONCLUSION: Thus, so far two @entity23 and two case-control studies are published with prophylactic bio-prosthetic reinforcement in stoma sites. The majority revealed significant better results in terms of @entity3976 and without any mesh-related complications in comparison to the non mesh group. Further, multicenter @entity23 are required to achieve a sufficient level of recommendation.
