Novel insights into the natural history of apical XXXX during long-term follow-up.

@entity1 @entity662 @entity1165 @entity943 @entity1353 @entity2791 @entity439 @entity583 @entity1121
BACKGROUND: Long-term follow-up in apical @entity1121 is rare. OBJECTIVE: To study the natural history of the disease. METHODS: We followed 11 @entity1 , 5 @entity1 and 6 @entity1 , for 5-20 years. RESULTS: At presentation all 11 @entity1 had typical features of apical @entity1121 , with @entity1353 in 3 and @entity662 in 8, of whom 5 were typical of angina and 3 had @entity583 . R-wave voltage and T-wave negativity progressively decreased in magnitude at serial electrocardiograms in four @entity1 . Perfusion defects were detected on thallium myocardial scintigraphy in three, increased apical uptake in two, and normal in one @entity1 . Apical @entity439 with normal coronary arteries developed in a @entity1 who had sustained @entity1165 . All of the 10 catheterized @entity1 had normal coronaries except for one with significant left anterior descending @entity2791 and another with a minor lesion. Symptomatic sustained @entity1165 was found in two @entity1 , one of whom required the implantation of an internal cardioverter defibrillator. CONCLUSIONS: Apical @entity1121 may develop morphologic and electrocardiographic changes with life-threatening @entity943 necessitating close follow-up and treatment.
