Waterjet hydrodissection: first experiences and short-term outcomes of a novel approach to XXXX resection.

@entity5 @entity1 @entity150
INTRODUCTION: TURB is the standard approach to @entity150 but suffers from several disadvantages. Waterjet hydrodissection is a new technology for removing superficial @entity5 in the GI tract promising to preserve the histological structures of biopsy specimens with favorable long-term results as recent studies have shown. The aim of this study was to show the feasibility and applicability of waterjet hydrodissection for removing papillary superficial @entity150 . MATERIALS AND METHODS: In five @entity1 diagnosed with superficial @entity150 , transurethral submucosal dissection was conducted using the T-type I-Jet HybridKnife (Erbe, Tuebingen). The resection edges were labeled by means of electrical coagulation with the HybridKnife. Subsequently, a submucosal fluid cushion specific to the tissue layer was formed by the waterjet implementation function of the HybridKnife, thereby elevating the tumorous tissue. The @entity5 was endoscopically extracted with a retrieval bag. Biopsy specimens of the @entity5 edges and base were subsequently collected. RESULTS: All @entity5 could be resected en bloc, and the lamina propria was intact in all specimens, allowing the pathologist to distinguish between superficial and invasive @entity5 . Pathological analysis confirmed R0 resection in all samples. CONCLUSION: These initial results prove the feasibility of waterjet hydrodissection for removing @entity150 . In contrast to conventional TURB, this new technique allows the pathologist to assess the entire lamina propria and the resection edges due to the en-bloc resection and to determine invasiveness as well as R0 versus R1 resection. These first results are promising, long-term oncological follow-up, and prospective randomized surveys investigating the recurrence rate have to be evaluated.
