XXXX : A @entity5 with an embryological origin?

@entity43 @entity1 @entity5 @entity189 @entity3 @entity444 @entity298
INTRODUCTION: In 1931, Simpson et  al. coined the @entity298 " to describe the regional spread of @entity43 as localized or extended with involvement of the peritoneal serous membrane and neighboring anatomical structures. Research into the origin of peritoneal @entity189 is based on two phases in a @entity1 's life: EMBRYO DEVELOPMENT: During week 3, the bilaminar disc becomes a trilaminar disc called the mesoderm. Inside the lateral plate mesoderm, the coelomic cavity is divided into 2 layers: the parietal (somatic) mesoderm, which gives rise to the parietal peritoneum and pleural surfaces; and the visceral (splanchnic) mesoderm, which gives rise to the visceral peritoneum, visceral surface of the pleura, @entity444 , and the muscular layer of the hollow viscera and its mesenteries. TUMOR SPREAD: Transcoelomic @entity3 and metaplasia of pluripotent stem cells in the peritoneum was involved in the pathogenesis of @entity43 . This involvement takes the form of a synchronous malignant transformation at multiple foci and may cause intraperitoneal field cancerization. Pluripotent stem cells play a role both in the development of the embryonic peritoneum and in the @entity5 . Consequently, knowledge of the origin of these cells (embryonic or current) could be extremely useful. The many markers that act during the embryonic period can affect descendants, that is, cells are already marked before specification and differentiation are activated. Thus, programmed activation could be attributed to genetic and epigenetic changes.
