Time course of symptoms in extracranial carotid artery dissections. A series of 80 XXXX .

@entity1 @entity64 @entity63 @entity18208 @entity1188 @entity385
BACKGROUND AND PURPOSE: @entity385 is the most frequent and severe manifestation of @entity18208 . However, few data exist on the precise time course of symptoms preceding the onset of @entity64 . METHODS: We studied 80 consecutive @entity1 (29 retrospectively, 51 prospectively) with angiographically diagnosed @entity18208 and, during a 6-month follow-up, recorded the time elapsed between the onset of the first symptoms and the onset of any @entity63 event (transient @entity63 attack or @entity64 ). We compared @entity1 with and without @entity63 events, with and without @entity64 , and, among @entity1 who had local signs at onset, those with and without subsequent @entity63 events. RESULTS: Cerebral or retinal @entity1188 occurred in 42 @entity1 . It was inaugural in 9 @entity1 . In the 33 others, the time interval between the first symptoms (local signs and/or transient @entity63 attacks) and the onset of @entity64 ranged from a few minutes to 31 days; it was < or = 7 days in 82% of the @entity1 . No significant difference in the baseline characteristics of the @entity1 or in the angiographic pattern of dissection was found based on the presence or absence of @entity63 signs or of @entity64 . CONCLUSIONS: In carotid artery dissections, @entity64 usually occurs in the first few days after the onset of the first symptoms, whether local or @entity63 , but it can occur as much as 1 month later. This suggests that any potential preventive treatment should be initiated as early as possible after the onset of the first symptoms but might also be worth initiating even 1 month later.
