The risk of XXXX in the asplenic adult.

@entity1 @entity295 @entity5 @entity102
The risk of @entity295 in @entity1 is well established. The risk of @entity295 following splenectomy in the adult remains unknown. This study provides data on this important subject. All adults (ages 16--91) who underwent splenectomies in three hospitals of the Louisiana State University Medical Center between 1965 and 1975 were identified. There were 298 @entity1 included in the study. Postsplenectomy information was collected on 256 @entity1 . The mean period of observation was 45 months (960 @entity1 years). There were seven deaths from fulminant @entity295 (incidence rate: 2.7%). Data were collected on 250 @entity1 who had either a gastrectomy or cholecystectomy without splenectomy. The mean period of observation was 61 months (1270 @entity1 years). There were no deaths due to fulminant @entity295 (p less than 0.05). When @entity295 was compared with the risk of @entity295 in the population at large (0.001%), the difference is significant (p less than 0.001). In the subgroup of 69 @entity1 with hematologic or @entity5 , there were three deaths from @entity295 (4.3%). In 187 @entity1 with no underlying diseases, four @entity1 developed @entity295 , which is an incidence of 2.2% (p less than 0.05 when compared with the population at large and control group). The risk of @entity295 appears to be greater in @entity1 with @entity102 , but has no relationship to age. These data speak for the conservation of splenic tissue when possible.
