Reaction time during semi-automated kinetic perimetry (SKP) in XXXX with advanced @entity227 .

@entity1 @entity227 @entity137 @entity66 @entity726 @entity6391 @entity1805 @entity1781
PURPOSE: This study aimed to evaluate @entity137 ( @entity137 ) in @entity1 with advanced @entity227 ( @entity227 ) loss using semi-automated kinetic perimetry (SKP). METHODS: Seventy-eight @entity1 with advanced @entity227 caused by @entity726 (31) or @entity6391 (19), homonymous @entity227 caused by post-chiasmal lesions (18) and unilateral @entity1781 ( @entity1781 ) (10) were examined with SKP (Octopus 101 perimeter). One eye in each @entity1 was enrolled. Additionally, VFs in the 10 healthy fellow eyes of the @entity1 with @entity1781 were compared with those in the 10 affected eyes. Reaction time was assessed during the SKP session by presenting kinetic stimuli (III4e) with constant angular velocities of 3 degrees /second moving linearly along so-called ' @entity137 vectors' at four different locations inside the III4e isoptre. Each stimulus presentation was repeated four times in randomized order. RESULTS: The geometric mean @entity137 was 794 ms (95% reference interval [RI] 391-1615 ms) in @entity1 with @entity726 , 702 ms (95% RI 306-1608 ms) in @entity1 with @entity6391 and 675 ms (95% RI 312-1460 ms) in @entity1 with @entity1805 . Increases in @entity137 for every 1 degree of eccentricity were 1%, 0.9% and 0.4%, respectively. The geometric mean @entity137 in the 10 @entity1 with @entity1781 was 644 ms in affected eyes and 435 ms in unaffected eyes, reflecting an increase of 51% (95% confidence interval 42-62%). CONCLUSIONS: We found substantial inter-subject variability in @entity137 in @entity1 with advanced @entity227 . It is possible to correct the position of the isoptres by assessing individual @entity137 . There were no relevant differences in @entity137 between the disease groups. Reaction time increases with eccentricity. In @entity66 ( @entity1781 ), @entity137 is prolonged, compared with in healthy fellow eyes. However, in clinical routine the @entity137 -related displacement of isoptres is negligible in the vast majority of cases.
