[Diagnosis and therapy of @entity1127 with special reference to XXXX ].

@entity1 @entity5115 @entity1127 @entity5 @entity189 @entity1586 @entity652 @entity12341 @entity1141
Colo-rectal adenoms occur more frequently in the elderly and should be considered as precancerous. The structural changes of the glandular epithelium are known as @entity1141 or atypia and are classified into three grades of severity; the " @entity5115 " has all the histological characteristics of a @entity5 which however has not infiltrated the muscularis mucosa and so has not gained access to the lymphatic system. Whenever these structural changes were present the terms focal @entity189 or @entity189 in situ were used. However in 1976 the WHO accepted to change the nomenclature to " @entity5115 ", as Morson had proposed. Their aim was to avoid superfluous radical surgical intervention. Whenever @entity12341 is present in an @entity652 , the necessary therapy is the local excision of the @entity652 together with its pedick. An exact complete histological examination is necessary. Between 1976 and 1980 we saw 201 cases of @entity1586 at the Surgical Clinic, University of D  sseldorf. 27 of these cases showed @entity5115 . As described in the literature there was a correlation between the size of the @entity652 , the histological picture and the risk of @entity5 . The reexamination of 105 @entity1 showed that there was a significant percentage of recurrency at the site of excision or new @entity1127 at a different site. Therefore, regular checkups are a must for all those @entity1 in whom @entity1127 of the large bowel have been removed.
