[Expression of @entity495 and XXXX in @entity189 ].

@entity1 @entity11266 @entity495 @entity5 @entity189 @entity28292 @entity11408
BACKGROUND AND OBJECTIVE: The gap junction plays an important role in the exchange of nutrients, ions, and regulatory molecules between cells. It will result in an uncontrolled cell proliferation if it is abnormal. It was reported that some @entity5 tissues and @entity5 cells had abnormal gap junction and restoration of the gap junction function could revert the @entity5 cells to a normal phenotype. Therefore, to investigate the expression of connexin(cx) in @entity1 @entity189 , may provide a new way for clinical diagnosis and the pathogenesis of @entity189 . METHOD: The expressions of @entity495 and @entity28292 in the biopsies of @entity189 ( @entity11408 ) and chronic @entity11266 tissues were determined by using the immunohistochemical staining. RESULTS: 1. @entity495 and @entity28292 expressed differentially in @entity11408 and chronic @entity11266 tissues(P < 0.01). In @entity11408 , expression of @entity495 and @entity28292 were 44.8% and 46.6%, respectively, while in columnar cells of chronic @entity11266 tissues, their expressions were 86.5% and 100% respectively, which were higher than those in @entity11408 , 2. The percentage in squamous epithelial cells of chronic @entity11266 tissues was 29.7%, which was lower than that in @entity11408 , (56.9%). 3. The expressions of @entity495 and @entity28292 in paracancer columnar epithelial cells were lower than that in paracancer squamous epithelial cells (P < 0.001), but higher than that in @entity11408 cells (P < 0.01). CONCLUSIONS: The abnormal expression of @entity495 and @entity28292 in nasopharynx tissues may be associated with cancerization and squamatization of @entity1 nasopharynx tissue.
