PROTEIN NEEDS OF CRITICALLY ILL XXXX RECEIVING PARENTERAL NUTRITION.

@entity1 @entity6841 @entity1674 @entity2041 @entity165 @entity1851
BACKGROUND: assess whether the current protein intake recommendations may improve the biochemical parameters of critical @entity1 receiving parenteral nutrition. METHODS: longitudinal study with three evaluations made (during the first 72 hours, on the 7th and the 14th days of @entity6841 ). The following tests were applied: albumin, @entity1851 , prealbumin, total @entity165 , HDL, @entity1674 , lymphocytes, and @entity2041 peroxidase. The severity was determined by SOFA. The statistical analysis included the Spearman and Mann-Whitney tests, as well as ANOVA (analysis of variance). RESULTS: among the 53 @entity1 evaluated, 20 (37.74%) died. The mean calorie was 24.68    9.78 kcal/kg (beginning of @entity6841 ), 26.49    8.89 kcal/kg (3rd to 7th days of @entity6841 ), and 30.9    12.19 kcal/kg (7th to 14th days of @entity6841 ). The mean protein was 1.19    0.44 g/kcal/kg (first 72 hours of @entity6841 ), 1.29    0.44 g/kcal/kg (3rd to 7th days of @entity6841 ) and 1.49    0.69 g/kcal/kg (7th to 14th days of @entity6841 ). Prealbumin, albumin, total @entity165 and HDL were below the reference values, while the CRP levels were high. Throughout the three evaluation times, there was no a significant improvement on the levels of laboratory examinations. A strong and negative correlation was found between SOFA and prealbumin (r = -0.64, p = 0.05). CONCLUSIONS: the protein offer, according to the traditional recommendations, was not enough to improve the biochemical parameters of critical @entity1 undergoing parenteral nutrition.
