Predictive value of rotational thromboelastometry during cardiopulmonary bypass for @entity882 and XXXX after weaning of cardiopulmonary bypass.

@entity1 @entity2002 @entity882 @entity1003 @entity6805
BACKGROUND: The early detection of @entity1003 helps guide decisions regarding optimal transfusion management during cardiac surgery. This study aimed to determine whether rotational thromboelastometry (ROTEM) analysis during cardiopulmonary bypass (CPB) could predict @entity882 and @entity6805 after CPB. METHODS: We analyzed 138 cardiac surgical @entity1 for whom ROTEM tests and conventional laboratory tests were performed simultaneously both during and after CPB. An extrinsically activated ROTEM test (EXTEM), a fibrin-specific ROTEM test (FIBTEM) and PLTEM calculated by subtracting FIBTEM from EXTEM were evaluated. Correlations between clot amplitude at 10 min (A10), maximal clot firmness, platelet count, and @entity2002 concentrations at each time point were calculated. A receiver operating characteristic analysis with area under the curve (AUC) was used to assess the thresholds of EXTEM, PLTEM and FIBTEM parameters during CPB and for predicting @entity882 and @entity6805 after weaning of CPB. RESULTS: The A10 on EXTEM, PLTEM, and FIBTEM during CPB showed a good correlation with platelet counts (r = 0.622 on EXTEM and r = 0.637 on PLTEM; P < 0.0001 for each value) and @entity2002 levels (r = 0.780; P < 0.0001) after CPB. A10 on a FIBTEM threshold of 8 mm during the CPB predicted a @entity2002 concentration < 150 mg/dl (AUC = 0.853) after CPB. Additionally, the threshold level of A10 on EXTEM during CPB for predicting platelet counts < 100,000 /  l after CPB was 42 mm (AUC = 0.768). CONCLUSIONS: EXTEM, PLTEM, and FIBTEM parameters during CPB may be useful for predicting @entity882 and @entity6805 after weaning of CPB.
