Metal stents improve @entity1282 , nutrition and survival in XXXX : a randomized controlled trial comparing modified Gianturco Z-stents with plastic @entity5274 .

@entity1 @entity5 @entity5274 @entity1282 @entity204
OBJECTIVE: To compare modified Gianturco metal stents with plastic @entity5274 in the palliation of @entity5 . DESIGN: @entity1 single-blind, multi-centre prospective, randomized trial. SETTING: Three district general hospitals in the Wessex region. @entity1 : Thirty one consecutive @entity1 with inoperable @entity5 causing @entity1282 and suitable for treatment with an endoprosthesis. INTERVENTIONS: @entity1 were randomized to receive either a modified Gianturco metal stent or a plastic Atkinson tube. Sedation was similar and @entity1 were given identical dietary advice. Data were collected after insertion until the @entity1 ' @entity204 . MAIN OUTCOME MEASURES: Procedural mortality/morbidity; hospital stay; weight loss; quality of life (Nottingham Health Profile, Spitzer QL index and specific questions about @entity1282 and enjoyment of food); duration of survival after insertion; cost effectiveness of each intervention. RESULTS: Overall complication rates were similar in the two groups. Compared with @entity5274 , @entity1 with Gianturco stents had better palliation of @entity1282 (median @entity1282 score 1 vs 2, P = 0.04), maintained their weight longer (median percent weight loss 0.66 vs 6.51, P = 0.007), enjoyed food more (enjoyment score 2 vs 1, P = 0.03) and survived longer (log rank P < 0.025). @entity1 with metal stents were discharged from hospital earlier (Gianturco 4 days, Atkinson 10 days, P = 0.001), and initial treatment cost was lower if the cost of hospital stay exceeded pound sterling 120 per day. CONCLUSION: Gianturco stents are superior to @entity5274 in the palliation of @entity5 .
