XXXX and pregnancy.

@entity1 @entity1596 @entity2099 @entity7375 @entity2403
PURPOSE: To report the course of @entity1596 activity during pregnancy and the postpartum period in @entity1 with @entity1596 . DESIGN: Observational case series. METHODS: The medical records of @entity1 with @entity1596 and pregnancy during follow-up at a large eye hospital were retrospectively reviewed. @entity1 with pregnancy were included in the study if follow-up was adequate to document the presence or absence of flare-ups in @entity1596 activity during the pregnancy and/or postpartum period. RESULTS: Seventy-six pregnancies among 50 @entity1 were included in the study. Thirty-three pregnancies were in @entity1 with @entity7375 , 19 were in @entity1 with @entity2403 , and 24 were in @entity1 with idiopathic @entity1596 . A flare-up in @entity1596 activity occurred within the first 4 months of pregnancy in 49 of 76 cases (64%) and later in pregnancy in 17 cases (22%); no flare-up occurred during pregnancy in 21 cases (28%). An @entity2099 flare-up was typical of @entity7375 and idiopathic @entity1596 . A flare-up within 6 months of delivery occurred in 38 of 59 cases (64%) that had adequate examination data available from the postpartum period. The postpartum flare-up was especially typical of @entity2403 . CONCLUSIONS: Many @entity1 with @entity1596 will experience a flare-up in disease activity within the first 4 months of pregnancy. Later pregnancy appears to be a time of relative disease inactivity. Many will experience a rebound in activity within 6 months of delivery.
