Cytologic features of ovarian granulosa cell tumors in XXXX .

@entity1 @entity1143 @entity146 @entity5 @entity722 @entity843
Adult @entity722 (AGCT) is an uncommon @entity5 of the ovary with potential for @entity146 and late recurrence. The most important prognostic factor for AGCT is @entity5 stage. Thus, cytological assessment of pleural or @entity843 fluids is crucial for initial @entity5 and subsequent @entity1 management. We report herein two cases of ovarian AGCT presenting with exfoliated @entity5 cells in pleural and @entity843 fluid. The first case involved a 61-year-old @entity1 who presented with stage Ic (a) AGCT. Seven years after initial diagnosis, @entity1143 and @entity1143 were identified. The second case involved a 50-year-old @entity1 who presented with stage IV AGCT with massive @entity843 and right @entity1143 . Fluid cytology from both cases showed cohesive or loose clusters of small uniform neoplastic cells with round-to-oval nuclei, coffee-bean-shaped nuclear grooves, small nucleoli, and scant cytoplasm. Call-Exner bodies were also observed in these cytologic specimens. In the differential diagnosis of small monomorphic @entity5 cells in @entity1143 or @entity843 , coffee-bean-shaped nuclear grooves and cell clusters forming Call-Exner bodies are diagnostic clues of AGCT.
