Close relationship between removal of circumflex iliac nodes to distal external iliac nodes and postoperative lower-extremity @entity4269 in uterine corpus malignant XXXX .

@entity1 @entity1029 @entity5 @entity4269
OBJECTIVE: The aim of this study was to confirm a causal relationship between removal of @entity1029 ( @entity1029 ) and lower-extremity @entity4269 after systematic lymphadenectomy in @entity1 with uterine @entity5 . METHODS: A retrospective chart review was carried out for all @entity1 with uterine corpus malignant @entity5 managed at Hokkaido Cancer Center between 1991 and 2013. All 318 @entity1 underwent @entity1029 dissection as a part of initial surgery and 217 @entity1 did not. @entity1 had undergone hysterectomy, bilateral salpingo-oophorectomy and lymphadenectomy and their medical records were reviewed. The type of lymphadenectomy gradually shifted from pelvic lymphadenectomy with @entity1029 to full lymphadenectomy without @entity1029 dissection during this period. We identified @entity1 with postoperative lower-extremity @entity4269 (POLEL). Logistic regression analysis was used to select the risk factors for POLEL. RESULTS: Of 535 @entity1 evaluated, POLEL was noted in the medical records of 126 @entity1 (23.6%), with median follow-up of 71months. The occurrence of POLEL was significantly higher in the @entity1029 -dissection group than in the @entity1029 -sparing group (34.3% vs. 7.8%, P<0.0001). Multivariate analysis confirmed that adjuvant radiation therapy [odds ratio (OR)=6.3, 95% confidence interval (CI)=2.6-14.9], resection of more than 31 lymph nodes (OR=2.0, 95% CI=1.2-3.5), and @entity1029 (OR=5.4, 95% CI=3.1-9.3) were independent risk factors for POLEL. CONCLUSIONS: Elimination of @entity1029 dissection can be helpful in reducing the incidence of POLEL.
