Mortality in XXXX .

@entity1 @entity410 @entity66 @entity1313 @entity5 @entity944 @entity302 @entity204 @entity3762 @entity159
Both community-based studies and reports from more selected @entity302 populations consistently reveal @entity1 with @entity302 to have a mortality rate two to three times that of the general population. This increased rate is most pronounced in @entity1 with remote @entity302 , although many studies also report a significant excess mortality also among those with @entity3762 . The highest standardized mortality ratios (SMR) are seen in young age groups, mainly due to the low expected mortality in @entity1 , and during the first 5-10 years after diagnosis. Many of these observations suggest that the higher mortality is partly related to the underlying disorder causing @entity302 rather than a direct consequence of the @entity410 . For example, mortality in @entity66 is increased, with SMRs ranging from 1.8 to 5.3 in the various studies. Deaths due to @entity5 , and in particular @entity1313 , is also increased among @entity1 with @entity302 . Accidents, @entity159 , and @entity944 ( @entity944 ) are more directly @entity410 -related causes of @entity204 . The incidence of such @entity204 vary considerably depending on the population being studied. While rare among @entity1 with new-onset @entity302 , @entity410 -related @entity204 may account for up to 40% of all @entity204 in @entity1 with chronic @entity302 . @entity944 is probably the most frequent @entity410 -related cause of @entity204 among young adults with @entity302 , with an SMR more than 20 compared with the general population. @entity410 -induced autonomic cardiorespiratory effects have been suggested, but the mechanisms behind @entity944 are far from fully understood. It appears, however, that the risk of @entity944 is closely related to @entity410 frequency, being 40 times higher in @entity1 who continue to have @entity410 than in those who are @entity410 -free.
