Cancer-Associated XXXX : The Bergen NORSTROKE Study.

@entity1 @entity32 @entity1851 @entity64 @entity39 @entity5 @entity1003 @entity10269 @entity1031 @entity3558 @entity385 @entity884
BACKGROUND: Underlying @entity5 can cause @entity385 in some @entity1 . Mechanisms include the affection of the coagulation cascade, @entity5 @entity3558 secretion, infections and nonbacterial @entity884 . The release of @entity39 factor and interleukins may cause @entity32 of the endothelial lining, creating a prothrombotic surface that triggers @entity1031 events, including @entity64 . The aims of this study were to assess the occurrence of @entity5 in @entity1 who had recently suffered an @entity385 and to detect possible associations between @entity64 and @entity5 subtypes. METHODS: All @entity385 @entity1 registered in the @entity64 Research Registry (NORSTROKE) as part of the ongoing Bergen NORSTROKE study were included. Blood samples were obtained on admission. @entity64 etiology was determined by the Trial of @entity10269 in Acute @entity64 Treatment (TOAST) criteria, and the severity of @entity64 was defined according to the National Institute of Health @entity64 Scale score. Information about @entity5 after @entity64 was obtained from @entity1 medical records and The Cancer Registry of Norway. RESULTS: From a total of 1,282 @entity385 @entity1 with no history of @entity5 , 55 (4.3%) @entity1 were diagnosed with @entity5 after @entity64 . The median time from @entity64 onset to @entity5 diagnosis was 14.0 months (interquartile range 6.2-24.5). Twenty-three (41.8%) @entity1 were diagnosed with @entity5 within 1 year and 13 (23.6%) within 6 months. The most common @entity5 (19.0%). By Cox regression analysis, @entity5 after @entity64 was associated with elevated D-dimer levels on admittance (p < 0.001), age (p = 0.01) and smoking (p = 0.04). CONCLUSIONS: Cancer-associated @entity64 is rare, and routine investigation for @entity5 seems unwarranted in acute @entity385 . However, in @entity64 @entity1 with elevated levels of @entity1003 factors, @entity1851 , higher age and a history of smoking, underlying @entity5 should be considered. Our study suggests that an unknown @entity64 etiology does not predict @entity5 .
