Mean platelet volume in euthyroid @entity1 with XXXX .

@entity1 @entity2621 @entity1955 @entity412 @entity6688 @entity65
UNASSIGNED: Mean platelet volume ( @entity6688 ) is the measure of platelet size. @entity6688 possibly is a simple way to estimate platelet activity. In this study, we aimed to investigate @entity6688 levels in @entity2621 @entity1 . Fifty-one euthyroid @entity1 with @entity2621 attending our outpatient clinic of the endocrinology department, and 51 age and BMI-matched healthy individuals were included in this study. All @entity1 with @entity2621 were at euthyroid state. None of the study @entity1 was subjected to @entity1955 replacement therapy. Anti-thyroid peroxidase (anti-TPO) antibody and anti-tiroglobulin antibody were positive. All the study @entity1 were evaluated by biochemical and platelet parameters. There were no significant differences in age (33.88  12.87 and 30.18  12.43 years, respectively; P>0.05) and BMI (23.55  3.34 and 22.25  3.65kg/m, respectively, P>0.05) between the study and the control groups. Anti-TPO and anti-tiroglobulin levels were significantly higher in the study group (anti-TPO 428.32  668.39IU/ml in the @entity2621 group; 14.85  9.66IU/ml in the control group, P=0.001; anti-tiroglobulin 320.46  796.05IU/ml in the @entity2621 group, 21.28  26.24IU/ml in the control group, P=0.09). There were no significant differences in terms of serum thyroid-stimulating hormone (TSH) (1.76  0.79 and 1.85  1.14uIU/ml, respectively), FT3 (3.10  0.37 and 3.29  0.76pg/ml, respectively) and FT4 (1.22  0.42 and 1.46  0.78pg/ml, respectively) levels between the study and the control groups. Serum @entity412 levels were significantly higher in the study group than in the control group (133.81  91.50 and 90.18  41.15mg/dl, respectively; P=0.015). Mean @entity6688 levels were significantly higher in the @entity2621 group than in the control @entity1 (8.8  1.05 and 7.9  0.79 fl, respectively; P=0.0001). To assess the correlation with @entity6688 , a Pearson's correlation analysis was performed on each variable. There were positive correlations between anti-TPO and @entity6688 levels (r=0.246, P=0.042), and between anti-tiroglobulin and @entity6688 levels (r=0.256, P=0.033). The multiple regression analysis of @entity6688 and other risk factors was performed. Age, BMI, C-reactive protein and waist circumference were independent predictive factors of @entity6688 . Adjustment for other factors did not alter these relative risks. Our results suggest that even if in euthyroid state, @entity1 with @entity2621 have higher @entity6688 levels than the healthy controls. As higher @entity6688 levels are closely related with @entity65 , @entity2621 @entity1 have greater risk of atherothrombotic complications than controls.
