[Effect of intravenous administration of fat emulsion to depancreatized XXXX ].

@entity235 @entity6178 @entity1560 @entity165
Sixteen mongrel @entity235 were depancreatized and controlled with intravenous hyperalimentation that included fat emulsion (Intralipid) for four weeks. Plasma lipids, fat tolerance test, PHLA, and presence of @entity1560 were investigated. @entity235 were divided into three groups (A, B, and C) for the purpose of studying the effect of fat emulsion. Groups A(n = 6) and B(n = 5) were given fat emulsion 1g/kg/day and 2g/kg/day respectively. Group C(n = 5) was not given fat emulsion. Group B had increased plasma total @entity165 and phospholipid. Group A had a slight increase of TG only. Group C had decreased plasma total @entity165 and phospholipid, and became hypoglycemic sometimes. The ability to clear fat emulsion expressed as (K2) decreased significantly after the 14th day in group B only. LPL, determined by the PHLA test in groups B and C only, did not change significantly. It seemed that fat emulsion was utilized in part as FFA and @entity6178 bodies. Infusion of fat emulsion did not lead to @entity1560 when insulin was administered continuously. For the depancreatized condition, it appeared that fat emulsion could be useful when blood sugar was controlled with insulin.
