Expired PCO2 as a prognostic indicator of successful resuscitation from XXXX .

@entity235 @entity1167
We performed a study to determine if the measurement of expired PCO2 during CPR for @entity1167 could be used as a prognostic indicator of successful resuscitation. Twelve mongrel @entity235 were fibrillated electrically, and external chest massage and assisted ventilation were applied for 15 minutes. Expired PCO2 and aortic and right atrial pressures were monitored each minute of arrest. Coronary perfusion pressure (CPP) was calculated by subtracting the right atrial from the aortic diastolic pressure. Half the @entity235 received high-force chest compression (80 lb) and half received low-force chest compression (40 lb). The six @entity235 that received high-force compression were resuscitated successfully. The expired PCO2 was significantly higher in the successfully resuscitated @entity235 (expired PCO2 = 9.6 +/- 3.2 mm Hg) when compared to those @entity235 that died (expired PCO2 = 3.2 +/- 1.1 mm Hg, P less than .01). Expired PCO2 was highly correlated (r = 0.91, P less than .01) with the CPPs. The measurement of expired PCO2 during attempted CPR may be useful as a noninvasive indicator of CPP and adequate technique. Further studies on the use of this technique as an assessment criterion are warranted.
