Impact of cardiovascular risk factors on severity of XXXX .

@entity1 @entity101 @entity6 @entity3657 @entity4218 @entity177 @entity613
OBJECTIVE: The development of @entity3657 is affected by the presence of cardiovascular risk factors. It is unclear, whether particular risk factors are leading to different clinical stages of @entity3657 . The aim of this retrospective cross-sectional study was to assess the association of cardiovascular risk factors with the presence of @entity4218 . METHODS: The study cohort was derived from a consecutive registry of @entity1 undergoing endovascular therapy in a tertiary referral centre between January 2000 and April 2014. @entity1 undergoing first-time endovascular intervention for chronic @entity3657 of the lower extremities were included. Univariate and multivariate logistic regression models were used to assess the association of age, sex, @entity6 , @entity101 , dyslipidaemia, smoking, and @entity177 with @entity4218 vs. @entity613 . RESULTS: A total of 3406 @entity1 were included in the study (mean age 71.7      11.8 years, 2075 [61%] male). There was a significant association of age (OR 1.67, 95%-CI 1.53-1.82, p  <  0.001), male gender (OR 1.23, 95%-CI 1.04-1.47, p  =  0.016), @entity6 (OR 1.99, 95%-CI 1.68-2.36, p  <  0.001) and @entity177 (OR 1.62, 95%-CI 1.35-1.96, p  <  0.001) with the likelihood of @entity4218 . Smoking was associated with @entity613 rather than @entity4218 (OR 0.78, 95%-CI 0.65-0.94, p  =  0.010), while @entity101 and dyslipidaemia did not show an association with @entity4218 . CONCLUSIONS: In @entity3657 @entity1 undergoing first-time endovascular treatment, age, male gender, @entity6 , and @entity177 were the strongest predictors for the presence of @entity4218 .
