Amino acid excesses for young XXXX : effects of excess methionine, tryptophan, threonine or leucine.

@entity1707 @entity9484 @entity4307 @entity563 @entity2228 @entity4336 @entity4022 @entity6778 @entity1017 @entity4857 @entity1460 @entity7836 @entity27653
Five experiments involving 359 weanling (8 kg) @entity1707 were conducted to evaluate the effects of dietary excesses of @entity7836 (Met), @entity9484 (Trp), @entity27653 (Thr) or @entity4307 (Leu) when added to a 20% crude protein @entity4336 - @entity1460 meal (C-SBM) diet. Experiments involved supplementing the basal diet with 0, .5, 1.0, 2.0 or 4.0% excesses of Met, Trp or Thr, or in the case of Leu, a 0, 1.0, 2.0, 4.0 or 6.0% excess. Levels of .5 and 1.0% excess Met did not depress feed intake (FI), @entity1017 (G) or gain/feed (G/F); 2.0 and 4.0% additions, however, depressed both FI and G but not G/F. Free Met in blood plasma increased linearly as dietary Met level increased, reaching over a 100-fold elevation at the highest Met level fed. Plasma Thr and @entity563 (Ser) increased, and @entity2228 ( @entity4022 ) decreased, with each added increment of Met. With Trp, only the 4.0% addition depressed FI and G (but not G/F). None of the levels of excess Thr depressed performance. Excess Thr, in fact, tended to increase G/F. Free Thr, Ser and @entity4022 in plasma increased linearly as graded increments of excess Thr were added to the diet. With Leu, a 6% addition depressed @entity1017 and food intake (but not G/F) but 1, 2 or 4% excesses were without effect. Plasma free Leu increased linearly while free @entity6778 and @entity4857 decreased as graded increments of Leu were added to the diet. These results suggest that @entity1707 can tolerate considerable excesses of Met, Trp, Thr and Leu without experiencing @entity1017 .(ABSTRACT TRUNCATED AT 250 WORDS)
