Hepatic XXXX from @entity521 .

@entity1 @entity5 @entity1576 @entity3 @entity521 @entity490
@entity521 is a common solid @entity5 of infancy and childhood. From 1967 to 1986 we evaluated and treated 58 @entity1 with @entity521 ; in ten (17%) of these @entity1 , symptomatic hepatic @entity3 developed. The ten @entity1 ranged in age from 2 days to 2 years 3 months. The most common symptoms attributable to hepatic @entity3 were abdominal enlargement, @entity490 , @entity1576 due to upward pressure on the diaphragm, and obstruction of the inferior vena cava. At the time of initial diagnosis, two @entity1 had stage III disease, three had stage IV disease, and five had stage IV-S disease. Six were initially given chemotherapy; all six of these @entity1 required radiation therapy when hepatic enlargement progressed. In the other four cases, radiation therapy was used alone or in combination with chemotherapy. Irradiation or irradiation plus chemotherapy produced complete resolution of local symptoms in seven cases, and a partial response in one case. The seven @entity1 who had a complete response are alive without evidence of recurrent disease; the remaining three @entity1 died of their @entity5 . The roles of chemotherapy, surgery, and radiation therapy in the management of symptomatic hepatic @entity3 from @entity521 are discussed.
