Hypertetraploid cells in vocal XXXX .

@entity1 @entity5700 @entity101 @entity1373 @entity602 @entity189 @entity19354 @entity1141
DNA measurements yield information about the nature of cells and may provide diagnostic and prognostic information. Static cytofluorometry was performed on smears removed at microlaryngoscopy from 107 @entity602 (96 @entity1 ). All stem cell lines were diploid except 3; 2 @entity189 and 1 severe @entity1141 were @entity5700 . The mean proliferative activity (percentage of nuclei greater than diploid peak) was 2.1% for the group of epithelia with @entity1373 and mild @entity1141 , 3.1% for those with @entity19354 , 4.0% for severe @entity1141 , and 6.8% for @entity189 . Hypertetraploid cell nuclei ( @entity101 cells) were not found in epithelia with @entity1373 and mild @entity1141 . Seven out of 15 @entity1 with epithelia showing @entity19354 had @entity101 cells; 5 of these @entity1 developed a @entity189 . One of 8 without @entity101 cells developed a severe @entity1141 . Nine @entity1 with severe @entity1141 had @entity101 cells; 4 had recurrences and 4 developed @entity189 within 4 years. In 14 @entity1 without @entity101 cells, 3 had recurrences and 1 developed a @entity189 6 years later. @entity101 cells were found in 15 @entity1 with T1 _ T2 @entity189 ; @entity189 was present in 2 after radiotherapy and 4 had recurrences within 11 months. Fourteen @entity1 with T1 _ T2 @entity189 did not have any @entity101 cells; one had @entity189 after radiotherapy and 3 had recurrences between 18 months and 4 years. DNA measurements and, especially, the demonstration of epithelia with @entity101 cells prove to be of prognostic importance.(ABSTRACT TRUNCATED AT 250 WORDS)
