Evidence that XXXX is present in @entity1 with @entity5818 and influences the outcome after surgery.

@entity1 @entity6220 @entity1931 @entity158 @entity5818
@entity5818 in the shoulder has generally been considered to be a clinical condition of mechanical origin. However, anomalies exist between the pathology in the subacromial space and the degree of @entity158 experienced. These may be explained by variations in the processing of nociceptive inputs between different @entity1 . We investigated the evidence for augmented @entity158 transmission ( @entity6220 ) in @entity1 with impingement, and the relationship between pre-operative @entity6220 and the outcomes following arthroscopic subacromial decompression. We recruited 17 @entity1 with unilateral impingement of the shoulder and 17 age- and gender-matched controls, all of whom underwent quantitative sensory testing to detect thresholds for mechanical stimuli, distinctions between sharp and blunt punctate stimuli, and @entity158 . Additionally Oxford shoulder scores to assess @entity158 and function, and PainDETECT questionnaires to identify 'neuropathic' and referred symptoms were completed. @entity1 completed these questionnaires pre-operatively and three months post-operatively. A significant proportion of @entity1 awaiting subacromial decompression had @entity158 radiating down the arm and had significant @entity1931 to punctate stimulus of the skin compared with controls (unpaired t-test, p < 0.0001). These are felt to represent peripheral manifestations of augmented central @entity158 processing ( @entity6220 ). The presence of either @entity1931 or @entity158 pre-operatively resulted in a significantly worse outcome from decompression three months after surgery (unpaired t-test, p = 0.04 and p = 0.005, respectively). These observations confirm the presence of @entity6220 in a proportion of @entity1 with shoulder @entity158 associated with impingement. Also, if @entity1 had relatively high levels of @entity6220 pre-operatively, as indicated by higher levels of @entity1931 and/or @entity158 , the outcome three months after subacromial decompression was significantly worse.
