Assessment of mild XXXX during over ground locomotion using linear discriminant analysis of inertial sensor data.

@entity1273 @entity1641
REASONS FOR PERFORMING STUDY: Hindlimb @entity1273 is common and can be difficult to diagnose or quantify in evaluating response to nerve blocks. An objective measure of @entity1273 can also be used to evaluate the effectiveness of the treatment's contribution to evidence-based medicine. The inertial sensor system can be used to capture 6 degree of freedom movement during over ground locomotion and here was used to quantify tuber coxae movement in nonlame and lame @entity1641 . HYPOTHESIS: Tuber coxae movement is useful for discriminating between nonlame and lame @entity1641 . OBJECTIVES: To measure left and right tuber coxae movement in lame and nonlame @entity1641 during over ground locomotion and to implement a linear discriminant analysis to discriminate between lame and nonlame @entity1641 . METHODS: Two inertial sensors were attached to the skin over left and right tuber coxae of 21 @entity1641 (9 mildly and 12 not lame). @entity1641 were trotted on a hard surface. A total of 1021 strides were collected. For each stride 34 features were extracted from the dorsoventral and craniocaudal movement and used in 2 different classification scenarios (lame vs. nonlame or left lame, right lame and nonlame) using linear discriminant analysis. RESULTS: Six degree of freedom inertial sensors were successfully used to collect kinematic data continuously from left and right tuber coxae in @entity1641 during over ground locomotion. These data were used for an automated classification of @entity1273 . In the first scenario, a sensitivity of 89% was achieved with a specificity of 75%. In the second scenario, all @entity1641 could be correctly assigned to the correct class in a simple 3 class reclassification test. POTENTIAL RELEVANCE: A mobile system that reliably detects and quantifies @entity1273 in @entity1641 during unconstrained locomotion could be a valuable tool to perform an evidence-based assessment of @entity1273 in @entity1641 in a clinical setting, e.g. before and after nerve blocks or before and after surgery.
