Treatment of mucocutaneous presentations of XXXX .

@entity1 @entity1033 @entity778 @entity12881 @entity23923 @entity3305 @entity281 @entity2025 @entity130 @entity9374
@entity2025 and II are diverse and quite frequent. After @entity281 , the virus establishes a life-long latency in the sensory ganglia and recrudescences may occur at an unpredictable rate. Recurrent @entity281 represent the majority of clinical manifestations of @entity2025 . Their management is currently well established using evidence-based medicine data. Primary @entity3305 is generally not treated with antivirals in otherwise healthy @entity1 , although intravenous @entity1033 may be offered in severe primary @entity281 , particularly in the immunocompromised @entity1 . The decision whether or not to treat recurrent @entity3305 should be evaluated individually and depends on the frequency and severity of relapses, the impairment of the quality of life, and the cost of therapy. @entity1 with mild disease may benefit from topical therapy, and those with severe and frequent recurrences may be considered for intermittent or long-term oral antiviral therapy. Primary @entity12881 is treated with oral or intravenous antivirals, depending on the severity of the @entity281 and associated symptoms. Recurrent @entity12881 can be managed with episodic short courses of oral antivirals in @entity1 whose recurrences are moderate to severe and rare, and have a clear prodrome. @entity1 with >5 episodes/year, severe recurrences or unrecognisable prodromes may be best managed with long-term suppressive antiviral prophylaxis. @entity778 is also responsible for a variety of other clinical manifestations, including herpetic @entity281 , disseminated and atypical @entity281 , @entity130 , @entity23923 , and @entity778 -associated @entity9374 . @entity2025 may also represent a complication following cosmetic procedures of the oro-facial region, surgical and dental interventions, sun exposure and burns. Precise treatment guidelines for these @entity2025 are not firmly established.
