Primary XXXX : a case report with immunohistochemical, ultrastructural, and cytogenetic features and review of the literature.

@entity2283 @entity242 @entity1326 @entity5 @entity2278 @entity5426 @entity2279 @entity1325 @entity1653 @entity2277 @entity2280 @entity2281
@entity5426 of the kidney is a rare @entity5 for which fewer than 10 case reports appear in the English literature. A case of primary @entity5426 is reported, in which the @entity5 showed poorly differentiated spindled @entity242 admixed with typical @entity1653 differentiation. Antibodies against @entity2279 , @entity2280 , Ulex europeus lectin type I, factor VIII-related antigen, cytokeratin ( @entity1325 / @entity1326 ), @entity2277 , @entity2281 protein, epithelial membrane antigen, carcinoembryonic antigen, @entity2283 , and smooth muscle actin were examined. @entity2279 showed strong diffuse membranous staining of cells in the well-differentiated areas and strong membranous staining in the spindled, poorly differentiated areas. @entity2280 showed strong cytoplasmic and membranous staining in both the poorly differentiated and well-differentiated areas. Staining for factor VIII-related antigen and Ulex europeus was less intense and was limited to the well-differentiated areas. Staining for cytokeratin ( @entity2278 ), @entity2281 , carcinoembryonic antigen, epithelial membrane antigen, @entity2283 , and smooth muscle actin were negative. Electron microscopy showed spindle cells containing abundant pinocytotic vesicles, @entity2277 -type intermediate filaments, and rare Weibel-Palade bodies. A complex karyotype was found. Our findings suggest that @entity2279 and @entity2280 are useful in defining endothelial differentiation in poorly differentiated @entity5426 in which reactions for Ulex europeus lectin type I and factor VIII-related antigen may be equivocal.
