Preventive Effect of XXXX Acellular Dermal Matrix on Post-thyroidectomy Scars and Adhesions: A Randomized, Double-Blinded, Controlled Trial.

@entity1 @entity3557 @entity7674 @entity73 @entity86
BACKGROUND: @entity7674 ( @entity7674 ) has been used for antiadhesion formation along with wound healing in various surgical fields. OBJECTIVE: The aim is to assess the efficacy of @entity7674 implantation in the prevention of @entity86 and adhesions after conventional, open, total thyroidectomy. MATERIALS AND METHODS: Forty-four @entity1 with @entity3557 undergoing thyroidectomy were randomly assigned to the study ( @entity7674 implantation) or control group (without @entity7674 ). Global photographic assessment, Vancouver scar scale (VSS), objective scar assessment, and swallowing impairment index were assessed at baseline, immediately after surgery, and at 1 and 2 months after surgery. RESULTS: Nineteen control and 20 study group @entity1 completed the study. The mean VSS score of the study group was significantly lower than the controls at both 1 month (3.06    1.25 vs 4.41    1.54, respectively) and 2 months (2.76    1.56 vs 4.35    1.58, respectively) after surgery. Scar quality measures (mean melanin and erythema indexes) were significantly lower in the study group compared with controls. Study group @entity1 had significantly lower swallowing impairment scores than controls. The mean postoperative hospitalization of both groups was not significantly different. CONCLUSION: @entity7674 -assisted implants appear to improve post-thyroidectomy scar and @entity73 without delays in operation time.
