Cervical @entity602 complicating multiple joint replacement in XXXX .

@entity1 @entity7194 @entity602 @entity134 @entity3799 @entity204 @entity309
The incidence of @entity3799 and @entity7194 was investigated in 48 @entity1 with @entity309 who had three or more major lower limb joint replacements. Eight (17%) developed @entity3799 requiring cervical fusion. This was the subsequent cause of @entity204 in two. Four further @entity1 demonstrated clinical features of @entity602 . Cervical @entity7194 was present in 29 of 44 (66%) in whom adequate radiographs were available. The development of cervical symptoms and signs could not have been predicted from the sex, age of onset, duration of disease or @entity134 therapy. Radiographic changes in the cervical spine were independent of major lower limb joint destruction and were often not present when planning a programme of joint replacement. Fifty-one control @entity1 were studied. Cervical @entity602 occurred in 2 (4%) and @entity7194 in 24 (47%). The development of rheumatoid changes in the cervical spine was unrelated to involvement of the hip or knee joints in the control group. There was a significant (p less than 0.05) increase in the incidence of @entity3799 in @entity1 with multiple lower limb joint replacements compared with the control population.
