[Anti- @entity7 therapy in the treatment of XXXX secondary to central @entity2994 ].

@entity1 @entity2402 @entity7 @entity2994 @entity1347 @entity2296 @entity941 @entity2297
PURPOSE: To evaluate the benefit of anti- @entity7 in the treatment of @entity1347 ( @entity1347 ), a severe complication of @entity2994 (CRVO). @entity1 AND METHODS: This is a retrospective case series of consecutive @entity1 with @entity1347 secondary to CRVO treated with anti- @entity7 . Ophthalmic parameters were recorded for each visit: measurement of best visual acuity (VA), intraocular pressure (IOP), iris examination, gonioscopy and fundus examination, and as necessary, @entity941 angiography and optical coherence tomography. Minimum follow-up was 6 months. RESULTS: Nineteen @entity1 (19 eyes) received intravitreal injections of anti- @entity7 in association with panretinal photocoagulation (PRP). In @entity1 who had uncomplicated @entity2296 without elevated IOP (n=6), after a mean of 3 injections, VA was stable in 4 @entity1 and improved by two lines in 2 @entity1 . In @entity1 with early @entity2297 ( @entity2297 ) (n=13), IOP reduction was observed in all eyes within 1 week after injection but increased secondarily after an average of 45 days, although the rubeosis had @entity2402 , which suggested that the change in IOP was independent of @entity1347 . After a mean of 6 injections in combination with filtering or cyclodestructive surgery, IOP finally stabilized, but VA decreased in all @entity1 . Three @entity1 (50%) with stage III @entity1347 progressed to stage IV @entity1347 in spite of anti- @entity7 treatment. CONCLUSION: In all eyes, anti- @entity7 treatment stopped neovascularization and helped to control IOP. However, vision was preserved only in the eyes with uncomplicated rubeosis at the time of diagnosis. Since only 32% of eyes were diagnosed at this stage, the authors suggest the prevention of @entity1347 by careful screening and follow-up of @entity1 at risk, and the performance of PRP in CRVO with extensive retinal non-perfusion prior to the onset of rubeosis.
