Cardio-ankle vascular index may be an important marker of silent XXXX after percutaneous coronary angiography and intervention: a prospective observational study on diagnostic accuracy.

@entity1 @entity1187 @entity3508 @entity528
OBJECTIVE: The relationship between silent @entity528 (SNI) and arterial stiffness assessed by cardio-ankle vascular index (CAVI) has not been evaluated in @entity1 treated with coronary angiography and intervention due to @entity1187 ( @entity1187 ). The aim of this study is to evaluate the value of CAVI in prediction of SNI after percutaneous coronary angiography and intervention in @entity1 presented with @entity1187 . METHODS: Eighty-three consecutive @entity1 presented with @entity1187 , who underwent percutaneous coronary angiography and intervention, were included in this prospective observational study on diagnostic accuracy. @entity3508 ( @entity3508 ) was studied before and 18 hour after the coronary angiography and intervention. CAVI was measured by VaSera-1000 instrument. Clinical and echocardiographic characteristics were analyzed and independent predictors of SNI were evaluated. Chi-square, Student t-test, Mann-Whithney U test, correlation analysis and logistic regression analysis was used for statistical analysis. RESULTS: @entity3508 levels significantly increased after cardiac catheterization (9.82  3.22 mg/dL vs. 13.15  8.55 mg/dL, p<0.001). CAVI (OR=2.992, 95% CI: 1.494-5.713, p=0.002), left ventricular ejection fraction (LVEF) (OR=0.911, 95% CI: 0.843-0.983, p=0.017) and undergoing percutaneous coronary intervention (OR=4.430, 95% CI: 1.034-18.97, p=0.045) were the independent predictors of SNI in logistic regression analysis. The cut-off value to show SNI for CAVI was 10.45 (sensitivity=71.8%, specificity=91.5%) in receiver operator charecteristic receiver operator charecteristic (ROC) curve analysis. The area under curve was 0.832 (95% CI=0.746-0.918, p<0.001). CONCLUSION: Besides undergoing PCI and having LVEF, measurement of CAVI may be a useful tool for predicting the development of SNI after percutaneous coronary angiography and intervention in @entity1 with @entity1187 .
