Nonoperative management of craniovertebral junction and XXXX .

@entity1 @entity66 @entity75 @entity51 @entity4048 @entity272 @entity378 @entity17096
BACKGROUND: Craniovertebral junction (CVJ) and @entity17096 ( @entity378 ) are both rare, each occurring in 0.3-1.0% of @entity1 . To our knowledge, there are no existing cases reporting these manifestations of @entity378 simultaneously. We report a case of @entity378 involving the left CVJ as well as the skin, and discuss our management while providing a review of the literature. CASE DESCRIPTION: An adult @entity1 was presented with progressive @entity4048 associated with the development of several @entity272 . Investigations revealed @entity75 including the left CVJ. Biopsy of the CVJ lesion was unamenable due to proximity of the vertebral artery; therefore, the @entity1 underwent biopsy of the other sites. Histological examination demonstrated features consistent with @entity378 and the @entity1 commenced 12 months of standard anti- @entity378 therapy with cervical spine immobilization. At 2-month review, the @entity1 was well with @entity4048 and cutaneous lesions. Repeat imaging at 6 months follow-up demonstrated a stable C1 lesion with no evidence of instability. CONCLUSION: CVJ @entity378 may be treated solely with anti- @entity378 therapy and immobilization to good effect if there is no gross instability or @entity51 . Similarly, @entity17096 responds well to standard anti- @entity378 therapy. Our experience suggests that co-existing @entity66 in the CVJ and skin can be simultaneously managed with standard therapy without significant alterations to treatment regimes or prognosis.
