[ XXXX secretion in @entity712 ].

@entity1 @entity712 @entity442 @entity2124 @entity18197
@entity2124 is a pituitary polypeptide hormone regulating growth in paediatric age as well as inducing anabolic actions directly or @entity442 mediated in adult age. Particularly, in many animals GH and @entity442 receptors were observed in cardiac myocyte membrane. GH modifies left ventricle structure and function. As concerns spontaneous GH secretion, some data suggest that pituitary gland can have a compensatory role on endocrine response to @entity712 . @entity712 stage was directly correlated to nocturnal GH levels. All GH spontaneous night secretion parameters as well as @entity442 levels showed a range between normal @entity1 and very high spontaneous secretion. Therefore in these @entity1 there are either a GH peripheric resistance or a reduction of the activity of GH/ @entity442 axis. Anyhow in our @entity1 , GH 24 hour infusion was inducing a 5 fold increase in GH concentration and a 50% increase in basal @entity442 levels. Anker et al. suggested to evaluate nutritional state in @entity712 @entity1 , observing no differences in non-cachectic @entity1 vs controls, while cachectic @entity1 presented a typical @entity18197 . Interestingly, cardiovascular effects of GH administration seem to be only marginally correlated to hemodynamic basal state. On the other hand basal hormonal setting of the @entity1 seems to correlate to the GH-induced cardiovascular response. In fact, low basal @entity442 but high basal GH @entity1 presented the worst endocrine and cardiovascular response to GH infusion. In literature there are controversial data about GH treatment in @entity1 with @entity712 . The heterogeneity of the population could be the reason for this discrepancy. Besides very different @entity442 responses to GH have been reported. Therefore, as there is good clinical evidence that GH acute infusion can improve @entity712 , it seems to be necessary firstly to evaluate the basal endocrine status of the @entity1 . Particularly attention should be given to those @entity1 that present a peripheric GH resistance. On the other hand, those @entity1 with a reduced pituitary GH reserve are supposed to have very beneficial effects from GH treatment.
