Platelet-rich plasma as a treatment for XXXX : comparison of a single versus two consecutive injections.

@entity1 @entity3669 @entity924 @entity158
BACKGROUND: platelet-rich-plasma is increasingly used in @entity924 . Ideal number of @entity3669 injections needed is not yet established. This study compares the clinical outcomes of a single versus two consecutive @entity3669 injections. METHOD: between December 2009 and January 2012, 40 athletes with @entity924 were treated by @entity3669 injection. @entity1 received single (20 @entity1 ) or two @entity3669 injections 2 weeks apart (20 @entity1 ). All @entity1 underwent prospective clinical evaluation, including Victorian Institute of Sport Assessment-Patella (VISA-P) score, visual analog scale (VAS) for @entity158 , and Tegner scale before @entity3669 and after a minimum of 2 year follow-up. RESULTS: 9 @entity1 failed @entity3669 treatment and needed surgery. 1 @entity1 was lost to follow-up. For the remaining @entity1 , the VISA-P, VAS, and Tegner scores all significantly improved from 35.2 to 78.5 (p = 0.0001), 6.6 to 2.4 (p = 0.0001), and 4.8 to 6.9 (p = 0.0003). @entity1 who received two injections had better scores than those who received single injection with VAS of 1.07 versus 3.7 (p = 0.0005), Tegner score of 8.1 versus 5.9 (p = 0.0003) and VISA-P of 93.2 versus 65.7 (p = 0.0001). CONCLUSIONS: two consecutive @entity3669 injections in @entity924 showed better improvement in outcomes when compared to single injection. LEVEL OF EVIDENCE: randomized prospective consecutive series, Level 2.
