XXXX in Indo-Asians in the North-West of England.

@entity1 @entity3548 @entity8 @entity731 @entity454
BACKGROUND: The incidence of @entity454 ( @entity454 ) in England is increasing. There is a higher incidence of @entity454 in British Indo-Asians than in the White population. AIM: To determine to what degree the increasing demand for renal replacement therapy in the UK is due to Indo-Asian @entity1 . To study the presentation to renal services of Indo-Asian @entity1 with @entity454 and report any inequalities in initial treatment of Indo-Asian @entity1 with @entity454 compared to their White counterparts. DESIGN: Prospective, inception cohort study. METHODS: Consecutive adult @entity1 with @entity454 who started renal replacement therapy between 1 April 2000 and 31 December 2001 in all 14 renal units serving an area from North @entity3548 , including Greater Manchester and Lancashire, were recruited and interviewed. RESULTS: Of the 578 @entity1 , 9.5% were Indo-Asian. The annual acceptance rate for renal replacement therapy was 342 per million population in Indo-Asians, compared with 91 per million population in the White population ( p < 0.001). Indo-Asian @entity1 with @entity454 were younger (median age 51 years vs. 60 yrs, p = 0.006) and more socially deprived (81% vs. 36.5% in the 5th Carstairs quintile, p < 0.001). A greater proportion of Indo-Asian @entity1 with @entity454 presented late to specialist renal services (31% vs. 19%, p = 0.03). Once adjusting for their younger age, @entity731 and/or hypertensive @entity8 was more prevalent in Indo-Asian @entity1 (OR 4.9; p = 0.03). There was no difference in the initial mode of maintenance dialysis or the perception of choice the @entity1 felt they had, based on their ethnicity. DISCUSSION: There is a silent epidemic of @entity454 in Indo-Asian @entity1 in the North-West, possibly vascular in aetiology, in which specialist intervention is late. This suggests that Indo-Asian @entity1 should be prioritized for early intervention strategies to reduce the burden of @entity454 .
