Lung reflexes and nasal vascular resistance in the anaesthetized XXXX .

@entity4485 @entity2951 @entity235 @entity20668 @entity551 @entity1168
1. In @entity4485 -anaesthetized @entity235 the nasal vasculature was perfused on both sides, and nasal vascular and airflow resistances were measured together with blood pressure, heart rate and tidal airflow. 2. @entity2951 was injected intravenously to stimulate lung C-fibre receptors, and @entity20668 to stimulate pulmonary stretch receptors and cardiac receptors. Injections with both drugs were repeated after pulmonary denervation and after cervical vagosympathectomy. 3. Intravenous @entity2951 caused @entity551 , @entity1168 and rapid shallow breathing, together with a decrease in nasal vascular resistance and little change in nasal airways resistance. Denervation showed that these effects came from lung reflexes, presumably from C-fibre receptors. 4. Intravenous @entity20668 caused similar effects to @entity2951 before denervations, presumably due to stimulation of slowly adapting pulmonary stretch receptors. Left atrial injections of @entity20668 caused @entity551 , @entity1168 and hyperpnoea, together with an increase in nasal vascular resistance and little change in nasal airways resistance. Thus cardiac receptors seem to increase nasal vascular resistance. 5. Injections of @entity2951 and @entity20668 into the nasal circulation decreased nasal vascular resistance, with a stimulation of breathing and changes in blood pressure. Denervations indicated that these were a combination of local and reflex actions.
