@entity2023 phenotypes based on mono- XXXX or poly- @entity566 .

@entity1 @entity32 @entity2023 @entity566 @entity56
BACKGROUND: @entity2023 ( @entity2023 ) is characterized by typical symptoms that are dependent on @entity32 . Poly- @entity566 is a frequent phenomenon. Phenotyping @entity2023 represents an up-to-date issue. OBJECTIVE: The aim of this study was to evaluate whether the number of @entity566 is able to define different phenotypes in @entity1 with @entity2023 . METHODS: 83 @entity1 (43 males, mean age 34.7 years) suffering from @entity2023 were evaluated. Sensitization, VAS for nasal symptoms perception, and nasal cytology were evaluated. RESULTS: Poly- @entity56 @entity1 perceived more severe nasal obstruction than mono- @entity56 ones (p  =  0.0006) as well as they had more frequent sneezing (p  <  0.0001). Moreover, poly- @entity56 @entity1 had a more intense inflammatory infiltrate, concerning both eosinophils (p  =  0.0005) and mast cells (p  =  0.0001), than mono- @entity56 @entity1 . CONCLUSIONS: The present study demonstrates that the presence of poly- @entity566 could define a distinct @entity2023 phenotype in comparison with mono- @entity566 . It could be clinically relevant as poly- @entity56 @entity1 have more intense @entity32 and more severe symptoms than mono- @entity56 ones.
