Diffuse proliferative XXXX after bone marrow transplantation.

@entity1 @entity1667 @entity644 @entity8 @entity4295 @entity631 @entity786 @entity810 @entity1985 @entity99 @entity1860 @entity617
A 15-year-old @entity1 developed @entity1985 and @entity810 4 years after allogenic bone marrow transplantation (BMT) for lymphoid crisis of @entity1860 . On admission, he presented with clinical features of chronic GVHD including transient exacerbation of @entity99 . Renal biopsy showed @entity631 with cellular crescents. The @entity1 was treated with @entity1667 pulse therapy (1 g/day, for 3 days) followed by oral @entity617 . Renal function gradually improved but @entity1985 state was persistent. A second renal biopsy showed improvement of @entity4295 and endocapillary proliferation and transformation of crescents into a fibrous form. After tapering of oral @entity617 , @entity786 was started, which resulted in a gradual improvement of @entity644 . Several cases of @entity1985 occurring after BMT have already been reported, but most cases had @entity8 . In our case, renal biopsy revealed @entity631 with findings of active cellular immunity, and aggressive treatment resulted in attenuation of these findings. Moreover, chronic @entity99 was noted at the time of this episode. Our findings suggest that chronic GVHD may be complicated with @entity631 through unknown cellular immune mechanism.
