Comparison of Intravenous XXXX with @entity1286 in @entity158 Relief of Long Bones Fractures: a Double Blind Randomized Clinical Trial.

@entity1 @entity174 @entity3652 @entity1286 @entity158 @entity12761 @entity130
INTRODUCTION: The selective medication for @entity158 control in many clinical situations is @entity1286 but its complications prevent its widespread use. @entity3652 has been introduced as an alternative for @entity1286 in some studies. However, the efficacy of its solitary use has not yet been evaluated. Therefore, the present study was undertaken to evaluate the effect of @entity3652 alone in relieving @entity158 in @entity130 @entity1 referring to an emergency unit. METHODS: In this double-blind clinical trial, @entity1 with long bone @entity174 were randomly divided into two groups of treatment with intravenous (IV) @entity1286 at a dose of 0.1 mg/kg and treatment with IV @entity3652 at a dose of 0.5 mg/kg. @entity158 severity of the @entity1 was recorded before and 10 minutes after injection based on numeric rating scale. The means in the two groups were compared using independent t-test. Then the Kaplan-Meier curve and log rank analysis were used to evaluate the success of treatment. RESULTS: 126 @entity1 were included in this study. The mean ages of the @entity1 in the @entity1286 and @entity3652 groups were 33.6  14.3 and 35.1  13.5 years, respectively (P=0.54). After therapeutic intervention, the @entity158 severity significantly decreased in @entity3652 (2.7  1.8; P<0.0001) and @entity1286 (2.4  1.5; P<0.0001) groups, with a similar effect of both medications on alleviating @entity158 (P=0.28). The success rate of the treatment at 10-minute interval in groups receiving @entity3652 and @entity1286 were 59 (93.65%) and 61 (96.8%) @entity1 , respectively (P=0.62). CONCLUSION: The results of the present study showed that administration of @entity3652 at a low dose (0.5 mg/kg) results in a significant decrease in the severity of @entity12761 in @entity1 with @entity174 of long bones. This palliative effect is very similar to that of @entity1286 .
