Early Operation for XXXX Complicated by Preoperative @entity999 Is Not Associated With Worsened Outcomes.

@entity1 @entity64 @entity548 @entity999 @entity794 @entity260 @entity281 @entity884
BACKGROUND: Valve operations for @entity1 presenting with @entity884 ( @entity884 ) complicated by @entity64 are thought to carry elevated risk of @entity260 . Our aim was to compare outcomes of @entity884 @entity1 who undergo surgical intervention early after diagnosis of @entity999 with outcomes of @entity1 without preoperative emboli. METHODS: All @entity1 undergoing operations for left-sided @entity884 between 1996 and 2013 at our institution were reviewed. @entity1 undergoing operations more than 14 days after @entity64 diagnosis (n  = 11) and those with  purely @entity548 (n  = 7) were excluded from the analysis. The study included 308 @entity1 who were stratified according to the presence (STR, n  = 54) or absence of a preoperative @entity999 (NoSTR, n  = 254). Primary outcomes of interest were the development of a new @entity64 and 30-day mortality. RESULTS: Mean time to surgical intervention from @entity64 onset was 6.0    4.1 days. @entity794  (39% STR vs 21% NoSTR, p  = 0.004) @entity281 at operation (52% STR vs 27% NoSTR, p  < 0.001) were more prevalent in STR @entity1 . There was  no significant difference in 30-day mortality (9.3% STR vs 7.1% NoSTR, p  = 0.57) or in the rate of new @entity64 (5 [9.4%] STR vs 12 [4.7%] NoSTR, p  = 0.19) between groups. In addition, there was no difference in 10-year survival between groups (log-rank p  = 0.74). CONCLUSIONS: Early surgical intervention in @entity1 with @entity884 complicated by preoperative @entity999 does not lead to significantly worse postoperative outcomes. Early surgical intervention for @entity884 after @entity64 warrants consideration, particularly in @entity1 with high-risk features such as @entity794 or annular abscess, or both.
