Retrospective Assessment of @entity717 Criteria for Mild @entity73 in XXXX .

@entity1 @entity73 @entity191 @entity1726 @entity717
UNASSIGNED: A @entity717 ( @entity717 ) taskforce recently proposed diagnostic criteria for @entity191 with features of mild @entity73 ( @entity1726 ). This study first examined the prevalence and nature of @entity1726 in a non-demented cohort using the @entity717 criteria. Using the generic Monte Carlo simulation method developed by Crawford and colleagues (2007), this study then estimated the base rate of the representative population who would demonstrate @entity1726 due to chance alone. A total of 104 @entity1 with idiopathic @entity1726 underwent extensive motor and neuropsychological testing at baseline and 2 years later. The Unified @entity191 Rating Scale (UPDRS) was used to assess motor symptoms of @entity1726 and a range of established neuropsychological tests was used to assess @entity1726 in accord with @entity717 criteria. In accord with @entity717 criteria, 38% of this cohort demonstrated @entity1726 at baseline and 48% at follow-up. Of the 36 @entity1 in the multiple-domain @entity1726 subtype at time-1, 9 (25%) demonstrated no @entity1726 at follow up. Analysis revealed that approximately 13% of the representative population would demonstrate abnormally low scores for 2 of the 9 tests used, thereby meeting @entity717 criteria for @entity1726 . Clinicians and researchers need to approach a single diagnosis (i.e., based on one assessment) of @entity1726 with considerable caution. (JINS, 2015, 21, 1-9).
