XXXX polymorphism in the @entity20822 gene and the risk of @entity43 : a meta-analysis.

@entity43 @entity41492 @entity20822 @entity534
UNASSIGNED: Numerous studies have evaluated the association between the @entity41492 polymorphism of the @entity20822 ( @entity20822 ) gene and @entity43 risk. However, the specific association is still controversial. This meta-analysis was therefore designed to clarify these controversies. Relevant case-control studies were enrolled in the meta-analysis. Quality evaluation of the included studies was conducted by two physicians. Statistical analyses were carried out using the Stata 12.0 software for meta-analysis. Analyses of sensitivity and publication bias were also conducted. Overall, a significant association was found between the @entity41492 polymorphism and @entity43 risk when all studies were pooled into the meta-analysis ( @entity534 / @entity534 vs His/His: OR = 1.85, 95%CI = 1.15-3.00; @entity534 / @entity534 vs @entity534 /His: OR = 1.17, 95%CI = 1.03-1.32; dominant model: OR = 0.84, 95%CI = 0.74-0.95; recessive model: OR = 1.69, 95%CI = 1.05-2.70). This meta-analysis suggested that the @entity20822 @entity41492 polymorphism was associated with the risk of @entity43 . Further large and well-designed studies are needed to confirm these conclusions.
