@entity10810 activity in XXXX .

@entity1 @entity1372 @entity177 @entity10810 @entity6192 @entity1098
Twenty healthy subjects and 39 @entity177 @entity1 ( @entity6192 - @entity1 ) maintained on chronic hemodialysis were used in this investigation to study the changes in @entity10810 ( @entity10810 ) activity of red blood cells (RBCs). The @entity6192 - @entity1 were all undergoing hemodialysis treatment. @entity10810 activity from the @entity6192 - @entity1 was determined before and after dialysis. An additional objective was to study the effect of @entity177 on @entity1 red blood cell aging. Blood samples were drawn from controls and @entity6192 - @entity1 in tubes containing @entity1098 or @entity1372 heparin as an anticoagulant. Red blood cells were purified to avoid interference with monocytes, reticulocytes and leukocytes. The purified RBCs were subfractionated into young (y) (1.08-1.09), mid (m) (1.09-1.11) and old (o) (1.11-1.12) percoll density (g/mL) fractions using a discontinous percoll gradient. The mean +/- SD @entity10810 per gram hemoglobin (U/g Hgb) activities in whole blood (WB), purified @entity1 red blood cells (PRBCs), young @entity1 red blood cells (y-RBCs), mid age @entity1 red blood cells (m-RBCs) and old @entity1 red blood cells (o-RBCs) in @entity6192 - @entity1 were 31.2+/-3.43, 29.3+/-3.26, 30.4+/-3.91, 25.1+/-5.25, 17.1+/-6.02 in females and 29.8+/-5.39, 28.8+/-5.29, 28.7+/-5.29, 23.7+/-5.39 and 16.0+/-5.60 in males. @entity10810 activity from @entity6192 - @entity1 were higher than that found in the control subjects. The aging of @entity1 RBCs in both the controls and @entity6192 - @entity1 showed a progressive reduction in @entity10810 activity. @entity10810 activity of RBCs from female @entity6192 - @entity1 were significantly higher (p < 0.05) than that of the female control subjects. The RBCs isolated from male @entity6192 - @entity1 showed a higher @entity10810 activity than control males, but a significant difference was only observed with the mid-age-cells. These studies further indicate that @entity10810 activity remained insignificantly different in the various density based age subfractions of RBCs of both @entity6192 - @entity1 and controls.
