Listing and transplanting adults with XXXX .

@entity1 @entity299
BACKGROUND: An increasing number of @entity1 with @entity299 ( @entity299 ) are reaching adulthood and may require heart transplantation. The survival of these @entity1 after listing and transplantation has not been evaluated. METHODS AND RESULTS: A total of 41 849 @entity1 (aged >18 years) were listed for primary transplantation during 1995-2009. @entity1 with a history of @entity299 (n=1035; 2.5%) were compared with those with other causes (non- @entity299 group) (n=40 814; 97.5%); 26 055 (62.3%) reached transplantation and were subdivided into those with (reoperation group; n=10 484; 40.2%) and without (nonreoperation group; n=15 571; 59.8%) a previous sternotomy. Survival on the waiting list was similar between groups, but mechanical ventricular assistance was not associated with superior survival to transplantation among @entity299 @entity1 . @entity299 @entity1 were more likely to have body mass index <18.5 at transplantation (P<0.0001), were younger, and had fewer comorbidities. Early mortality among @entity1 with @entity299 was high (reoperation, 18.9% versus 9.6%; P<0.0001; nonreoperation, 16.6% versus 6.3%; P<0.0001), but by 10 years, overall survival was equivalent (53.8% versus 53.6%). Analysis was limited by the lack of specific information regarding the @entity299 diagnosis in most @entity1 . CONCLUSIONS: Adults with @entity299 have high 30-day mortality but better late survival after heart transplantation. Mechanical circulatory assistance does not improve waiting list survival in these @entity1 . This may be due to a combination of highly complex reoperative surgery and often poor preoperative systemic health.
