Perfusion computed tomography in XXXX .

@entity1 @entity63 @entity2791 @entity854 @entity731
BACKGROUND: Diffusion- and perfusion-weighted imaging after @entity63 ( @entity63 ) has been well studied, while less data exist on perfusion computed tomographic (PCT) imaging. OBJECTIVES: To examine the frequency of @entity854 in @entity1 with anterior circulation @entity63 and to identify factors associated with the presence of @entity854 . DESIGN: Retrospective study. SETTING: Academic hospital. @entity1 : Sixty-five consecutive @entity1 admitted to Rush University Medical Center, Chicago, Illinois, between June 1, 2007, and November 30, 2009, for anterior circulation motor or aphasic @entity63 in whom PCT was performed. MAIN OUTCOME MEASURES: Using an automated software algorithm, perfusion abnormality was defined as brain tissue associated with a mean transit time greater than 145% of that of the contralateral hemisphere and cerebral blood volume greater than 2.0 mL/100 g. Demographic, risk factor, clinical, radiographic, and in-hospital outcome data were reviewed. RESULTS: Of 65 @entity1 with anterior circulation @entity63 who underwent PCT (median age, 62.4 years; 49.2% male), 22 (33.8%) had focal perfusion abnormalities. The presence of motor symptoms (95.5% vs 67.4%, P = .01), multiple (>1) episodes (18.2% vs 2.3%, P = .04), @entity2791 greater than 50% or occlusion (77.3% vs 11.6%, P < .001), large-artery @entity731 subtype (59.1% vs 9.3%, P < .001), and subsequent in-hospital events (22.7% vs 0%, P = .001) were more frequent in those with perfusion abnormality. CONCLUSIONS: On acutely performed PCT, one-third of @entity1 with hemispheric @entity63 have perfusion abnormalities. Perfusion abnormality may mark @entity1 at greater risk for subsequent early deterioration. This requires further study.
