XXXX : impact of clinical factors on prognosis in a histologically revised series.

@entity1 @entity5 @entity189 @entity2103 @entity158 @entity3
OBJECTIVE: To analyze clinical data and possible prognostic factors of @entity1 with @entity189 of the parotid gland. STUDY DESIGN: A retrospective study was made of 85 @entity1 with suspected @entity5 who were admitted to the Center of Head and Neck Oncology at Odense University Hospital (Odense, Denmark) from 1975 to 1994. METHODS: @entity1 records were retrospectively reviewed and tabulated for relevant clinical parameters. A complete revision of histological examination was performed by the same pathologist and the @entity5 were classified according to the 1991 international guidelines from the World Health Organization. @entity5 (6%) did not fulfill the criteria of @entity5 and were reclassified as benign. In another five cases the assumed primary @entity189 were found to be metastatic disease from @entity5 of the breast, prostate, skin, and lungs. Ten @entity1 (12%) were excluded from the analysis, leaving 75 individuals for the study. RESULTS: Twenty-four percent of @entity1 were classified as T1, 32% as T2, 15% as T3, and 28% as T4. One @entity1 (1%) was not classifiable (TX). Regional lymph node @entity3 were found in 17 cases (23%). Two of these were classified as N1 (3%), 2 as N2A (3%) and 13 as N2B (17%). Four @entity1 were registered as not classifiable (NX) (5%). No @entity1 were classified as N3. Distant @entity3 were found in four @entity1 (5%) (one @entity1 had bone and liver @entity3 and three @entity1 had lung @entity3 ). Five-year recurrence-free survival of the entire study group was 63%, disease-specific survival was 69%, and crude survival was 52%. In univariate analysis, @entity5 size, histological appearance, T status, stage, the presence of lymph node @entity3 , distant @entity3 , @entity158 had a significant influence on survival. CONCLUSIONS: A thorough histological revision is pivotal in retrospective @entity189 studies, and @entity5 size; histological appearance; T, N, and M status; stage; @entity2103 ; and @entity158 from the face and/or neck seem to be significant prognostic indicators for @entity1 with primary @entity189 .
