Metastatic @entity3557 misdiagnosed as non-small [corrected] cell XXXX .

@entity1 @entity3557 @entity5 @entity2 @entity1149 @entity4755 @entity358 @entity3745 @entity259 @entity7457
BACKGROUND: @entity2 , two @entity5 with similar immunohistological characteristics, have vastly different biologic behaviors and treatment approaches. As @entity259 commonly spread to the lungs, metastatic @entity259 should be included in the differential diagnosis of a @entity358 or lesions. SUMMARY: A 54-year-old @entity1 with a remote history of @entity1149 was found to have FDG avidity in the thyroid and right cervical lymph nodes. Subsequent ultrasonographic findings and FNA cytology led to a total thyroidectomy, bilateral central lymphadenectomy, and right modified radical lymph node dissection for primary @entity259 . Reviews and comparisons of the pulmonary and cervical surgical specimens revealed that the @entity1 had been misdiagnosed for the previous 6 years; she had metastatic @entity3557 to the lung. The @entity1 's original diagnosis of @entity5 was based upon the original lung biopsy showing positive @entity7457 ( @entity7457 ) immunostaining. The original diagnosis was questioned because of her long survival when she was diagnosed with locally advanced @entity3557 . Further analyses of the immunohistological characteristics of both surgical specimens--including staining for @entity7457 , @entity3745 , @entity4755 , S-100, and CEA--documented the correct diagnosis. CONCLUSIONS: A thorough understanding of the natural history and surgical pathology, including immunohistology, of lung and @entity259 is necessary for a correct and timely diagnosis and appropriate treatment. Because @entity7457 expression is seen in both @entity2 , careful consideration should be given to both @entity5 when evaluating @entity1 with thyroid and pulmonary nodules.
