Changes in the pattern of infection caused by XXXX .

@entity1 @entity4789 @entity1310 @entity295 @entity6793 @entity4195 @entity281 @entity272 @entity204 @entity13171
The distribution of T- and M-protein antigens was determined in 12,469 cultures of @entity4195 sent to a reference laboratory. Of these 7232 (58%) were isolates from hospital @entity1 , 249 (2%) from hospital staff and 4988 (40%) from the community. The survey extended from January 1980 to June 1987. During this time the numbers of isolates of M-types 6, 49 and 81 rose then fell, being replaced by types 1, 3 and 28. The proportion of isolates of M-types 4 and 12 remained constant. Few strains were received from cases of @entity1310 or @entity4789 but there has been an increase in the number of strains from serious @entity281 and @entity204 . Forty-four of the 55 (80%) strains received since 1985 from fatal @entity281 have belonged to M-type 1. All other strains, bar two, received from fatal @entity281 in those years belonged to M-type 3. Representatives of M-type 1 were also associated with @entity13171 . Types 3 and 4 predominated among the isolates from scarlet fever, types 1, 4, 12 and 49 from @entity1310 , types 49 and 81 from @entity272 in meat workers and type 28 in cases of @entity295 . The M-typability rate was 97% but new M antigens await definition among strains causing @entity6793 .
