XXXX receptor imaging. The presence of @entity1943 receptors in @entity309 .

@entity1 @entity571 @entity11033 @entity158 @entity1943 @entity309 @entity12306
OBJECTIVE: To investigate the in vivo and in vitro expression of @entity1943 receptors (SS-R) on synovial membranes of @entity1 with @entity309 ( @entity309 ). METHODS: The joints of 14 consecutive @entity1 with active @entity309 , 4 @entity1 with severe @entity571 ( @entity571 ), and 30 control @entity1 were studied. The @entity1943 analog [111In- @entity12306 -D-Phe1]-octreotide was used for in vivo SS-R scintigraphy, and the @entity1943 analog @entity11033 for in vitro SS-R autoradiography. RESULTS: Seventy-six percent (220 of 290) of the @entity158 and 76% (207 of 274) of the swollen joints of the @entity1 with @entity309 were visualized by SS-R scintigraphy. The degree of @entity158 and swelling correlated well with positive scintigraphy findings in the joints (P < 0.0001). In 2 of the @entity309 @entity1 who underwent scintigraphy, as well as in 4 of 5 other @entity1 , in vitro studies of the synovial membranes showed the presence of specific SS-R. In @entity1 with @entity571 , uptake of radioactivity in the affected joints was significantly lower than that in @entity1 with @entity309 . None of the joints of the control @entity1 demonstrated uptake of radioactivity. CONCLUSION: SS-R are present in the synovial tissue of @entity1 with active @entity309 , as demonstrated by both in vivo and in vitro techniques. The potential value of SS-R scintigraphy in the clinical evaluation of @entity1 with active @entity309 is presently unknown.
