Clues to recognition of fungal origin of XXXX .

@entity3355 @entity5 @entity75 @entity364 @entity17101 @entity6656 @entity378
The present study addresses the specificity of @entity3355 for distinguishing among @entity5 , @entity378 , and @entity364 . Osseous impact is used in this manuscript as a convention to describe the macroscopic appearance of defleshed bones affected by the disease. Osseous changes in the skeleton of a 47-year-old black male, diagnosed in life as having @entity17101 , were characterized and compared to @entity75 observed in ten individuals with @entity378 and six with @entity5 in the Terry and Hamman-Todd Collections. Apparent distinguishing characteristics are identified. Eroded areas, present as fronts of resorption or the result of space-occupying masses in @entity17101 , with protruding, short, blunt, 1 x 2 mm spicules of new bone, are surrounded by periosteal reaction. These differed from smooth zones of resorption and coalesced lesions, with a smoothed marginal zone and space-occupied appearance--bone-displacing mass--in @entity378 and lytic (nonpermeative) lesions of @entity5 . Displacing is a convention (an artificial term) denoting bone resorption and reformation at the outer edge of the @entity5 mass, giving the impression that the surrounding bone had expanded beyond its original margins. Irregular trabeculae are occasionally preserved in the margins, but remodeling in the form of blunting of those trabeculae is not observed macroscopically in either @entity378 or @entity5 . Two apparently specific lesion types are noted in @entity17101 . Periosteal reaction surrounding fronts of resorption appears specific, at least for nonarticular osseous @entity75 , among the three entities studied. Remodeling of isolated internal trabeculae in the space-occupying mass lesions of @entity17101 also appears unique among the three disorders studied. Comparison with @entity6656 suggests that extrapolation of @entity17101 findings to other @entity364 is feasible; description of additional clinically diagnosed cases is awaited.
