Epidemiologic features of XXXX in Taiwanese adults involving native valves.

@entity1 @entity712 @entity6 @entity1457 @entity16 @entity177 @entity1576 @entity884
Little is known about the incidence and clinical outcomes of @entity884 ( @entity884 ) involving native valves in Asian countries. This nationwide study investigated epidemiologic features and in-hospital mortality associated with @entity884 in adults (age > or =18 years) based on Taiwan's National Health Insurance database from 1997 through 2002. Of 7,240 enrolled @entity1 with @entity884 involving native valves, the mean age was 53 +/- 19 years and 70% were @entity1 . The mean annual crude incidence was 7.6 per 100,000 inhabitants. The incidence was significantly higher in @entity1 than in @entity1 (10.4 vs 4.6 per 100,000; p <0.001). The incidence of @entity884 increased steadily with age, ranging from 3.8 per 100,000 @entity1 in @entity1 <30 years of age to 33 per 100,000 @entity1 in @entity1 > or =80 years of age (p <0.001). Staphylococcal (32%) and streptococcal species (61%) were the most common causative pathogens. The mean in-hospital mortality rate was 18%. Multivariate analysis showed that male gender, older age (> or =50 years), @entity6 , @entity712 , @entity16 , @entity177 , @entity1576 , @entity1457 , and Staphylococcus species as the causative microorganism were independent predictors of in-hospital mortality. In conclusion, this Taiwanese study revealed a high incidence of @entity884 in @entity1 and elderly subjects. The in-hospital mortality rate remained high. @entity1 with @entity884 who also developed @entity1457 and @entity1576 were the most likely to have a poor outcome.
