Overexpression of a stress-inducible XXXX dehydrogenase gene from @entity958 in transgenic plants improves stress tolerance.

@entity6453 @entity137 @entity7574 @entity66 @entity8863 @entity3280 @entity75 @entity958 @entity26 @entity1219 @entity274 @entity1110 @entity1234 @entity3125 @entity39692 @entity264
In plants, oxidative stress is one of the major causes of damage as a result of various environmental stresses. @entity66 is primarily because of the excessive accumulation of reactive @entity26 species (ROS). The amplification of @entity75 is further stimulated by the accumulation of @entity137 degradation products, i.e. @entity3125 , arising from reactions of ROS with lipids and proteins. Previously, the isolation of dehydration-inducible genes encoding @entity264 dehydrogenases (ALDHs) was reported from the desiccation-tolerant plant Craterostigma plantagineum and @entity958 . ALDHs belong to a family of @entity1110 -dependent enzymes with a broad substrate specificity that catalyze the oxidation of various @entity137 @entity3125 to @entity7574 . Analysis of transcript accumulation revealed that Ath- @entity39692 is induced in response to @entity1219 , heavy metals ( @entity8863 and @entity3280 ), and chemicals that induce oxidative stress ( @entity6453 (MV) and @entity274 ). To investigate the physiological role and possible involvement of ALDHs in stress protection, we generated transgenic @entity958 plants overexpressing Ath- @entity39692 . Transgenic lines show improved tolerance when exposed to dehydration, @entity1219 , heavy metals ( @entity8863 and @entity3280 ), MV, and @entity274 . Tolerance of transgenic plants is correlated with decreased accumulation of lipid peroxidation-derived reactive @entity3125 (as measured by @entity1234 ) compared to wild-type plants. Increased activity of Ath- @entity39692 appears to constitute a detoxification mechanism that limits @entity264 accumulation and oxidative stress, thus revealing a novel pathway of detoxification in plants. We suggest that Ath- @entity39692 could be used to obtain plants with tolerance to diverse environmental stresses.
