Increased XXXX clearance in @entity1230 @entity1 with normal serum @entity1011 : a retrospective observational study.

@entity1 @entity14488 @entity1230 @entity1213 @entity1011 @entity130
INTRODUCTION: The aim of this study, performed in an @entity1213 ( @entity1213 ) population with a normal serum @entity1011 , was to estimate urinary @entity1011 clearance ( @entity14488 ) in a population of @entity1230 @entity1 (PT) through a comparison with a population of non @entity130 @entity1 (NPT). METHODS: This was a retrospective, observational study in a medical and surgical @entity1213 in a university hospital. A total of 284 @entity1 were consecutively included. Two different groups were studied: PT (n = 144) and NPT (n = 140). Within the second week after admission to the @entity1213 , renal function was assessed using serum @entity1011 , 24 h urinary @entity14488 . RESULTS: Among the 106 @entity1 with a @entity14488 above 120 mL minute(-1) 1.73 m(-2), 79 were PT and 27 NPT (P < 0.0001). Only 63 @entity1 had a @entity14488 below 60 mL minute(-1) 1.73 m(-2) with 15 PT and 48 NPT (P < 0.0001). @entity1 with @entity14488 greater than 120 mL minute(-1). 1.73 m(-2) were younger, had a lower SAPS II score and a higher male ratio as compared to those having @entity14488 lower than 120 mL minute(-1). 1.73 m(-2). Through a logistic regression analysis, age and @entity130 were the only factors independently correlated to @entity14488 . CONCLUSIONS: In @entity1213 @entity1 with normal serum @entity1011 , @entity14488 , is higher in PT than in NPT. The measure of @entity14488 should be proposed as routine for PT @entity1 in order to adjust dose regimen, especially for drugs with renal elimination.
