Effects of @entity3413 on pro-inflammatory cytokines in @entity1 with XXXX .

@entity1 @entity32 @entity296 @entity3413 @entity1007 @entity310 @entity1199 @entity731 @entity165
BACKGROUND: The role of @entity32 in the development of @entity731 and its complications has been recently documented. Pro-inflammatory cytokines are among many postulated factors. It is possible that the imbalance between protective cytokines and cytokines affecting endothelial function is one of the underlying mechanisms of @entity296 . AIM: To examine the effects of @entity3413 on @entity1199 and @entity310 levels in @entity1 with @entity1007 . METHODS: The study group consisted of 64 males (age 20-65 years) with @entity1007 . The control group was composed of 10 healthy male volunteers (age 25-40 years) with normal lipid profile. Total @entity165 , LDL- @entity165 , @entity1199 and @entity310 were measured in both groups at baseline, after three months of dietary treatment, and after a further three months of @entity3413 therapy. RESULTS: @entity3413 caused a significant decrease in the total and LDL- @entity165 levels compared both with baseline measurements (p=0.0001) and after dietary treatment (p=0.0001). Moreover, @entity3413 significantly reduced the @entity1199 plasma concentration (p=0.0003). There were no significant differences between @entity1199 levels before and following dietary treatment. The @entity310 serum concentration significantly decreased following the implementation of diet (p=0.0001). Subsequent @entity3413 therapy caused further decrease in the @entity310 serum concentration but this difference did not achieve statistical significance. CONCLUSIONS: A hypolipemic diet significantly decreases @entity310 serum concentration without affecting the @entity1199 level. The subsequent @entity3413 therapy significantly reduces @entity1199 but not @entity310 when compared with the post-diet values.
