Randomized double-blind controlled trial comparing room-temperature and heated XXXX for @entity616 .

@entity227 @entity3303 @entity158 @entity616
STUDY OBJECTIVE: To determine whether warming of @entity3303 decreases the @entity158 of its injection during @entity616 . DESIGN: Prospective, randomized, double-blind, controlled trial. INTERVENTIONS: Twenty healthy volunteers received bilateral digital nerve blocks of their middle finger. They were first randomly assigned to receive either room-temperature (21 degrees C) or heated (42 degrees C) 2% @entity3303 in their first block. They were then randomly assigned to receive the first block in either the right or left hand. The blocks were performed in a standardized fashion by a single physician, who was blinded to which solution was being used. The volunteers rated the @entity158 of each digital block on a 100-mm visual analog scale (VAS). Efficacy of each digital block was tested at 5 minutes. RESULTS: Heating of the @entity3303 was associated with a significantly lower median @entity227 score (31.5 versus 25.0; P < .05). There was no difference in @entity158 score between the two solutions in relation to which hand was used (P = .29) or whether the injection was the first or the second (P = .37). When all factors (temperature, order, and hand) were considered in the ANOVA with respect to @entity227 score, the only significant relation found was that between the temperature of the solution and the @entity227 score (P = .028). CONCLUSION: Heating of @entity3303 decreases the @entity158 of injection during @entity616 .
