Are XXXX produced during the intraesophageal acid perfusion test?

@entity1 @entity32 @entity5836 @entity2910 @entity4681 @entity158 @entity4423
Many years ago, it was proposed that the symptoms of heartburn correlated more closely with acid-induced @entity4423 than with the presence of @entity32 . This concept, however, has not been evaluated by modern manometric techniques. We monitored intraesophageal pressures during acid perfusion (O.1N @entity5836 ) in 17 reflux @entity1 with gross @entity2910 and positive @entity158 response and 17 age-matched controls. Using a low-compliance infusion system, amplitude, duration, velocity, and the presence of simultaneous and repetitive contractions in the body of the esophagus were evaluated. Amplitude did not change in either group. Duration did increase significantly during acid perfusion in reflux @entity1 , but not in controls. Mean duration between groups, however, was similar before and during acid perfusion. No simultaneous contractions were observed, while three @entity1 and two controls had repetitive contractions. A significant decrease in velocity was observed in both groups during acid perfusion. These studies indicate that acid-induced @entity4681 are neither a common accompaniment nor necessary for the production of acid-induced @entity158 in the esophagus.
