Volumetric changes in transplanted vascularized fat flaps after @entity63 or congestive stresses and their relationship to XXXX in a zucker fatty @entity35 model.

@entity35 @entity2478 @entity1050 @entity63
BACKGROUND: The aim of this study was to examine volumetric changes in fat flaps after stresses as well as their relationship with @entity2478 ( @entity1050 ) in a Zucker fatty @entity35 model. METHODS: A total of 12 male Zucker-fa/fa @entity35 were randomly divided into two stress groups. Superficial epigastric fat flaps were evaluated on the right side as control and on the left side as the stress ( @entity63 or congestive) condition in the same @entity35 in order to avoid biases. Stress conditions were made by obstructing the pedicle vessels with a vascular clip for 3 hours. The volumes of these flaps were measured weekly. After 12 weeks of measurements, the @entity1050 of harvested flaps was examined in histologically immunostained sections. Percent changes in the body-weight-corrected flap volume [cFV(%)], the stress/control ratio [FV-ratio(%)], and the stress/control ratio of @entity1050 ( @entity1050 ) were defined. RESULTS: cFV(%) 12 weeks after surgery was 34.7        26.7 in the control flaps and 13.2        10.5 in the stress flaps. The FV-ratio(%) after 12 weeks was 7.4-202.5 (70.2        77.9) in the @entity63 group and 14.6-66.3 (37.7        22.2) in the congestive group. The difference in variance between two groups was significant (P   =   0.030). cFV(%) correlated with total @entity1050 (P   =   0.011). The FV-ratio(%) correlated with the @entity1050 (P   =   0.002). CONCLUSIONS: Weekly measurements of flap volumes in the Zucker fatty @entity35 model were new and useful methods. The FV-ratio(%) in the congestive group decreased at a constant rate, while that in the @entity63 group decreased or increased slightly. The rate of decreases in the flap volume correlated with @entity1050 .    2015 Wiley Periodicals, Inc. Microsurgery, 2015.
