Impact of Intravenous XXXX on @entity548 During Endoscopic Sinus Surgery.

@entity1 @entity390 @entity548 @entity190 @entity391 @entity927 @entity50
INTRODUCTION: Endoscopic sinus surgery is a common procedure performed by otolaryngologists. This study evaluated the efficacy of intravenous (IV) @entity927 (TA) on @entity548 in @entity1 undergoing elective @entity50 ( @entity50 ). MATERIALS AND METHODS: The present study was performed in 170 @entity1 scheduled for @entity50 surgery under general anesthesia in order to examine the effects of IV TA on providing a bloodless surgical field and to evaluate the amount of @entity548 . One hundred @entity1 received intravenous TA and 70 @entity1 received placebo. @entity548 was estimated by the attending anesthesiologist at the end of surgery by accounting for @entity190 and irrigation fluid in a 25 mL-graded suction canister and nasopharyngeal packing (measured weight of packing on the electronic scale). Hemodynamic variables were monitored and coagulation profile was determined. RESULTS: A total of 170 @entity1 (90 male [53%] and 80 female [47%]), mean age 30.54  4.14 years, were evaluated. There was a significantly lower @entity548 volume in the TA group than in the placebo group (107.7  45.1 vs. 189.3  51 mL; P<0.001). There was no significant difference between pre- and postoperative hematocrit (38.81   4.20 vs. 36.60   3.35) or pre- and postoperative hemoglobin (12.51   2.5 vs. 11.64  1.9) levels in the TA group (P>0.05). Moreover, the difference between the TA and control groups regarding postoperative hematocrit (34.65  4.45 vs. 36.60  3.35) and hemoglobin (10.81  2.1vs. 11.64  1.9) levels was not significant (P>0.05). Vomiting and @entity390 in the control group was greater than in the control group, but the difference was not significant (P>0.05). We did not detect significant coagulation alterations in the TA group. CONCLUSION: TA significantly decreased @entity548 without increasing side effects such as alteration in coagulation parameters, hemodynamic changes, and @entity391 and @entity390 . Use of TA can avoid the need for antihypertensive agents to reduce @entity190 in @entity50 .
