Use of postoperative radiotherapy for node-positive XXXX .

@entity1 @entity5 @entity1149 @entity1442 @entity86 @entity1349
The appropriate @entity1 selection for adjuvant radiotherapy after primary surgical therapy of @entity1149 ( @entity1149 ) is unclear. Four thousand thirteen @entity1 diagnosed from 1988-1995 in 9 registry areas of the Survival, Epidemiology, and End Results program who received primary surgical therapy for pathologic stage T1-3 N1/2 M0 @entity1149 were identified. County-level and @entity1 -specific variables associated with the use of postoperative radiotherapy (PORT) were studied by multivariate logistic regression analysis. Prognostic factors for cause-specific survival (CSS) and @entity1349 ( @entity1349 ) were determined by Cox multivariate analysis. Overall, 58% of node-positive @entity1 received PORT. Use of PORT was independently associated with younger age, more @entity1442 , no prior @entity5 , less extensive surgery than pneumonectomy, and @entity1 residence close to a radiotherapy facility. In multivariate analysis of the entire node-positive population, there were no differences in @entity1349 or CSS with the use of PORT. In the @entity1 with N2 disease, PORT was associated with improved @entity1349 (5-year @entity86 , 22% with PORT; P = 0.001) and CSS (5-year CSS: 25% without PORT, 30% with PORT; P = 0.02). Additionally, @entity1 with = 4 nodes involved also had an improved survival in association with PORT (5-year @entity1349 : 11% without PORT, 18% with PORT; P = 0.001; 5-year CSS: 17% without PORT, 25% with PORT; P = 0.009). Therefore, recognizing the inherent limitations of a retrospective, registry-based analysis, @entity1 with more @entity1442 appear to have an improved survival with the use of PORT.
