Psychotic symptoms in XXXX : a diagnostic dilemma?

@entity1 @entity146 @entity75 @entity303 @entity16 @entity1833 @entity747 @entity179 @entity716 @entity4943 @entity10963
BACKGROUND: @entity4943 ( @entity4943 ) constitutes a spectrum of @entity179 associated with @entity75 . The clinical heterogeneity is evident, and early diagnosis is a challenge. The primary objectives were to characterize @entity716 , initial clinical diagnoses and family history in neuropathologically verified @entity4943 - @entity1 and to analyze possible correlations with different neuropathological findings. METHODS: The medical records of 97 consecutive @entity1 with a neuropathological diagnosis of @entity747 ( @entity747 ) were reevaluated. Psychotic symptoms ( @entity1833 , delusions, @entity10963 ), initial diagnosis and family history for @entity146 were analyzed. RESULTS: Psychotic symptoms were present in 31 @entity1 (32%). There were no significant differences in age at onset, disease duration or gender between @entity1 with and without @entity716 . Paranoid ideas were seen in 20.6%, and @entity1833 and delusions in 17.5% in equal measure. Apart from a strong correlation between @entity716 and predominantly right-sided @entity75 , the majority of @entity1 (77.4%) were tau-negative. Only 14.4% of the @entity1 were initially diagnosed as @entity4943 , while other types of @entity303 were seen in 34%, other @entity146 in 42%, and 9.2% with other @entity16 . The @entity1 who were initially diagnosed with a @entity146 were significantly younger than the @entity1 with other initial clinical diagnoses. A positive heredity for @entity303 or other @entity146 was seen in 42% and 26% of the @entity1 respectively. CONCLUSIONS: Psychotic symptoms, not covered by current diagnostic criteria, are common and may lead to clinical misdiagnosis in @entity4943 .
