XXXX in Lung Transplant Candidates: Role of Routine Invasive Assessment.

@entity1 @entity3979 @entity453 @entity731 @entity850
UNASSIGNED: Background: An @entity731 burden sufficient to put lung transplant candidates at risk for end-organ disease after transplantation is considered to be a relative contraindication for lung transplantation. Objectives: The aim of this study was to assess our current practice of cardiac workup by coronary angiography in lung transplant candidates >= 50 years of age. Methods: We retrospectively analyzed 50 consecutive lung transplant candidates >= 50 years of age in which coronary angiography was performed at the University Hospital Zurich (2009-2013). For every @entity1 , the risk of developing an acute coronary event was estimated by using a recalibrated version of the PROCAM study calculator for the Swiss population. Results: The median estimated risk of developing an acute coronary event within 10 years in the study cohort (n = 50) was 4.2% (interquartile range 1.9-7.6), which is considered to be a low risk. Sixteen percent of @entity1 were considered to be at intermediate risk. In 66% of @entity1 , coronary angiography showed no @entity453 ( @entity453 ). In 28% of @entity1 , @entity453 without significant @entity850 was diagnosed. In 6% of @entity1 , significant @entity3979 was detected requiring percutaneous coronary intervention. No correlation between the coronary status and the risk score or cardiovascular risk profile was found. Conclusions: The high prevalence of asymptomatic @entity453 without correlation to a common clinical risk score supports the important role of coronary angiography for the assessment of coronary artery status. This approach might prevent cardiovascular events and improve long-term survival after transplantation.    2015 S. Karger AG, Basel.
