Elevated serum levels of resistin, leptin, and @entity1254 are associated with @entity1851 and also other clinical conditions in XXXX .

@entity1 @entity627 @entity1254 @entity309 @entity617 @entity1851
OBJECTIVE: Body fat is an important source of hormones and cytokines (adipokines) that not only regulate the energy balance, but also regulate the inflammatory and immune responses. This study investigated the association of clinical conditions with serum levels of adipokines in @entity1 with @entity309 . METHODS: Serum levels of resistin, leptin, and @entity1254 were measured by enzyme-linked immunosorbent assay in 141 @entity1 (110 @entity1 ) who fulfilled the 1987 revised criteria of the American @entity627 Association for the diagnosis of @entity309 and in 146 normal controls (124 @entity1 ). Then the correlations between adipokine levels and clinical parameters were evaluated. RESULTS: The serum resistin level did not differ between the @entity1 and controls. However, serum leptin levels were significantly higher in male and female @entity309 @entity1 than in the corresponding controls, while the serum @entity1254 level was significantly higher in female @entity1 than in female controls. Multivariate analysis revealed that predictors of an elevated resistin level were female sex and @entity1851 ( @entity1851 ), while the leptin level was related to the body mass index and @entity1851 . Predictors of an elevated @entity1254 level were the use of @entity617 and @entity1851 , however, @entity1851 was negatively associated with @entity1254 in @entity1 with @entity309 . CONCLUSION: The serum levels of resistin and leptin were positively associated with @entity1851 level in @entity1 with @entity309 , suggesting that these adipokines may act as pro-inflammatory cytokines in this disease. The serum @entity1254 level was elevated in the @entity1 , however, it was negatively associated with @entity1851 level. In addition, the serum levels of resistin, leptin, and @entity1254 were also associated with female sex, BMI and the use of @entity617 , respectively.
