Working XXXX : construct validity and treatment effects.

@entity1 @entity27 @entity2786
STUDY OBJECTIVE: To better understand the effects of @entity27 ( @entity27 ) on working memory performance. We first examined the construct validity of a working memory task (the 2-Back task) and its relationship to other tests of cognitive functioning, and then determined the effects of positive airway pressure ( @entity2786 ) treatment on measures of both working memory and its related component processes. METHODS: Fifty-six @entity1 with @entity27 were administered cognitive tests of working memory and related subordinate cognitive processes prior to initiation of @entity2786 treatment and at a 3-month follow-up visit. Objective monitors were employed to measure @entity2786 treatment adherence. Statistical analyses were conducted to examine treatment adherence and cognitive performance over time. RESULTS: Performance on the 2-Back task was statistically correlated with both a second working memory task (PASAT) and all subordinate cognitive measures. @entity1 were separated into high and low @entity2786 adherence groups using a median split of 4 hours of @entity2786 use per night. Repeated measures ANOVAs demonstrated that high adherers performed better across time on both tests of working memory (2-Back: F46 = 4.73, p <0.04; PASAT: F46 = 4.92, p <0.04) whereas low adherers performed more poorly. There were no treatment effects for any other cognitive measure. CONCLUSIONS: The 2-Back task demonstrated adequate construct validity as a measurement of working memory in individuals with @entity27 . Our treatment adherence findings suggest that the construct of working memory is more sensitive to the effects @entity27 treatment than are any of its subordinate cognitive processes.
