[Treatment of early stage primary tonsil XXXX ].

@entity1 @entity1893 @entity34
OBJECTIVE: To investigate the treatment for @entity1 with early stage primary tonsil @entity1893 ( @entity1893 ). METHODS: Two hundred and thirteen @entity1 with previously untreated early stage primary tonsil @entity1893 were reviewed. All @entity1 were pathologically confirmed. According to Ann Arbor classification, 35 @entity1 were stage I, 178 stage II. The primary treatment for stage I was radiotherapy alone in 12 and combined modality therapy (CMT) in 23 @entity1 . The primary treatment for stage II was radiotherapy alone in 57,chemotherapy alone in 2, and CMT in 119 @entity1 . RESULTS: The 5-year overall survival, cancer specific survival (CSS) AND disease-free survival (DFS) for the early stage primary tonsil @entity1893 were 65%, 70% and 61%, respectively. The 5-year CSS was 63% for the radiotherapy alone group and 72% for the CMT group (p = 0.064), and the 5-year DFS were 56% for the radiotherapy alone group and 62% for the CMT group. For @entity1 with stage I disease, The 5-year CSS were 100% in both radiotherapy alone and CMT groups, and the 5-year DFS were 100% and 80% in these two groups (p = 0.148), respectively. There was no significant difference of efficacy between the two treatment s for the @entity1 with stage I disease. For the @entity1 with @entity34 , the 5-year CSS was 58% in radiotherapy alone group and 66% in CMT group (p = 0.051). However, CMT significantly improved DFS in @entity34 , with a 5-year DFS of 46% for radiotherapy alone and 60% for CMT (P = 0.046). CONCLUSION: @entity1 with stage I tonsil @entity1893 treated with radiotherapy alone or CMT can achieve an excellent outcome. CMT significantly improve the DFS in stage II @entity1 . There was a trend that CMT improved the survival rates in the @entity1 with early stage disease. It was suggested that CMT should be used for the @entity1 with early stage primary tonsil @entity1893 .
