Usefulness of coronary pressure measurement for functional evaluation of XXXX .

@entity1 @entity63 @entity75 @entity256 @entity177
Despite the widespread adoption of drug-eluting stent (DES) implantation, the optimal treatment of @entity177 remains challenging. The present study evaluated the relation between quantitative angiography and the fractional flow reserve (FFR) in @entity75 after DES implantation and the efficacy of FFR in determining whether to treat these lesions. To assess their functional significance, the coronary pressure-derived FFR was measured in 50 DES @entity75 (49 @entity1 ). Additional intervention was performed in lesions with a FFR <0.8. Major adverse cardiac events were assessed at 12 months after the reintervention procedure. The mean percent diameter stenosis (%DS) was 58    13%. Of the 50 lesions, 20 (40%) were deferred without additional intervention. The FFR and %DS had a negative correlation (r = -0.61, p <0.001). However, when only the lesions with @entity256 (15 lesions) were analyzed, the degree of correlation decreased (r = -0.56, p = 0.12). Although most lesions (89%) with a %DS of >= 70 had significant functional @entity63 , among 41 lesions with a %DS <70, only 20 (49%) had demonstrated functional patency. The incidence of adverse events during the 12 months of follow-up after FFR-guided treatment was 18.0% (23.3% in the FFR <0.80 group and 10.0% in FFR >= 0.80 group). In conclusion, a discrepancy was found between functional @entity63 measured by the FFR and the angiographic %DS, in particular, in moderate- or diffuse-type @entity75 after DES implantation. The outcome of FFR-guided deferral in @entity1 with DES in-stent restenosis seems favorable.
