Volumetric assessment of lymph node @entity3 in @entity1 with XXXX treated with chemotherapy.

@entity1 @entity5 @entity189 @entity3 @entity44
INTRODUCTION: We evaluate volumetry and RECIST (Response Evaluation Criteria In @entity5 ) as methodologies for response after chemotherapy for non-seminomatous @entity5 with retroperitoneal lymph node @entity3 . METHODS: We performed a retrospective analysis of non-seminomatous @entity5 and concurrent retroperitoneal lymph node @entity3 , which received chemotherapy and had computed tomography scans before and after treatment. Volumetric analysis and RECIST criteria were used to calculate response rates. We included a new category (favourable response) for @entity1 with response rates between <100% and >70%. We calculated the correlation between volumetric and RECIST criteria with histological and clinical variables. RESULTS: In total, 18 @entity1 met the inclusion criteria. Histopathologic analysis of orchiectomy showed @entity44 in 55.5% of @entity1 , and those without @entity44 had predominantly @entity189 . The mean baseline volume of retroperitoneal @entity3 was 447 cc, the mean post-chemotherapy volume was 33.6 cc, and the response rate was 62.6%. According to RECIST criteria, the mean baseline diameter was 4.93 cm, the mean post-chemotherapy diameter was 2.39 cm, and the response rate was 42.4%. Large post-chemotherapy residual masses correlated in both classifications with @entity44 . The response rate was associated with the need for surgical treatment and the volumetric classification correlated with the need for lymphadenectomy. CONCLUSIONS: This study evaluated volumetry as a way to measure clinical response in lymph node @entity3 of @entity5 . Volumetric analysis is the next step in the evaluation of response rate; its accuracy remains to be determined. @entity44 had greater residual masses and our classification correlated with the need for lymphadenectomy.
