Recurrence rates after neuroendoscopic fenestration and Gamma Knife surgery in comparison with subtotal resection and Gamma Knife surgery for the treatment of XXXX .

@entity1 @entity227 @entity5 @entity45 @entity976
OBJECT: The object of this study was to compare the recurrence rates of @entity976 after @entity45 fenestration combined with Gamma Knife surgery (GKS) and after subtotal resection (STR) combined with GKS. METHODS: The records of 27 @entity1 (age range 3-66 years) with @entity976 that were treated surgically or neuroendoscopically before GKS between January 2000 and December 2007 were reviewed to compare recurrence rates. The @entity1 were divided into 2 groups: Group 1 (13 @entity1 ) received the neuroendoscopic procedure before GKS, and Group 2 (14 @entity1 ) received an STR followed by GKS. @entity5 volumes, radiation doses, @entity227 , endocrine levels, and recurrences were compared between the 2 groups. @entity1 with solid @entity5 and those who underwent complete resection were excluded from the study. RESULTS: The recurrence rate for Group 1 was higher than that of Group 2 (p = 0.046). The radiation dose near the optic chiasm was higher in Group 1 (p = 0.021) than in Group 2. However, endocrine function was better preserved in Group 1 than in Group 2. CONCLUSIONS: This investigation confirms that STR followed by GKS results in a lower recurrence rate than neuroendoscopy and GKS. Neuroendoscopy and GKS, however, results in a better preservation of endocrine function. These results suggest that a generalized multimodal approach including endoscopic fenestration in addition to GKS is hindered by higher recurrence rates.
