Surgery on @entity977 in XXXX in a subarctic region.

@entity1 @entity2847 @entity227 @entity2013 @entity5 @entity735 @entity977 @entity652
The present series consists of 18 consecutive @entity1 with @entity977 operated on between 1977 and 1979 using the transfrontal route. Ten @entity652 were 10, 20 or 30 times the normal maximum size of the pituitary measured according to Di Chiro and Nelson's (2) index (Table 2). @entity5 without obvious suprasellar growth were operated on using the trans-sphenoidal route and thus are not included in the present series. Large and @entity977 are preferably removed by the transfrontal route and using microsurgical techniques. Really poor vision associated with @entity5 seem to improve but not to normal level. @entity735 stays blind. @entity227 returns to normal (Table 4). Prolactin values associated with @entity2013 are extremely high and may remain raised even after apparently radical extirpation. @entity5 -containing sellar crypts associated with these large @entity5 may be responsible for this observation. Postoperative radiotherapy and @entity2847 administration therefore seem advisable. Further operations may be necessary on @entity1 with extensive posterior or lateral growths. Redundant partially intraosseous @entity5 fragments may be more easily removed later, possibly owing to the beneficial effects of radiation therapy. It is hoped that large and @entity652 in the future will pass into history, even in the peripheral parts of the world. The trans-sphenoidal approach is always a better solution than the transfrontal approach whenever it can be carried out, but it requires earlier diagnosis.
