@entity27 : a XXXX .

@entity1 @entity4094 @entity2749 @entity66 @entity26 @entity27 @entity2147 @entity3316 @entity7672 @entity943
@entity27 is a @entity66 with pathologic sequelae that become apparent after a number of years. @entity1 with @entity27 generally present with @entity2147 , and diagnosis is eventually established through observation of the @entity1 during sleep. @entity1 with @entity27 snore loudly and experience nocturnal @entity26 desaturation and repetitive disruptions from sleep that eventually lead to daytime @entity2147 . Numerous complex interactive pathophysiologic events occur during each obstructive episode, and it is important for the clinician to be aware of the cardiopulmonary, neurologic, and anatomic abnormalities associated with this condition. The anatomic configuration of the pharynx and the physiologic response to occlusion of the upper airway have a major role in the pathogenesis of this disorder. Alveolar ventilation during an apneic episode is immediately reduced to zero, and the metabolic demands for @entity26 must be met by @entity26 stores within the body. With repetitive episodes of obstruction, the @entity26 stores within the lungs are diminished and the rate of arterial @entity7672 desaturation increases. During @entity2749 , the systemic blood pressure increases while heart rate and cardiac output decrease. Bradydysrhythmias have been noted with the obstructive @entity2749 , and @entity943 are associated with episodes of severe @entity7672 desaturation. Coexisting @entity4094 in @entity1 with @entity27 contributes to the development of @entity3316 , serious gas exchange derangement, and general cardiovascular instability.
