[Study of 3D-pcASL in differentiation of @entity385 and acute XXXX ].

@entity1 @entity64 @entity198 @entity1009 @entity385
OBJECTIVE: To investigate the value of three-dimentional pseudo-continuous arterial spin labeling (ASL) perfusion imaging in differentiating @entity385 from acute @entity198 . METHODS: From September 2013 to September 2014, 42 @entity1 with actue @entity64 onset and 20 healthy volunteers underwent conventional brain MRI DWI and 3D-ASL Perfusion Imaging in our hospital. Only 20 @entity1 whose lesions located in the middle cerebral artery (MCA) territory were enrolled in this study. Of these cases, 12 cases were diagnosed with @entity385 , 8 were diagnosed with @entity198 . First, we analyzed the imaging features of the 20 @entity1 and 20 volunteers. Then, CBF values of the lesions in the 20 @entity1 and the gray matter of MCA territory in the 20 volunteers were measured on 3D-pcASL images. Third, the difference of mean CBF values between @entity1 and volunteers were analyzed. RESULTS: Out of 20 study group, 19 @entity1 whose lesions presented high signal intensity on DWI images, 12 cases were @entity385 and 8 were @entity198 . All the lesions of 20 cases showed abnormal perfusion on 3D-pcASL images. 3D-pcASL has good consistency with DWI in diagnostic capabilities (  (2) = 0.565, P = 0.01). On 3D-pcASL, 11 @entity385 @entity1 presented perfusion defects or low perfusion, 1 @entity385 @entity1 showed high perfusion, 8 @entity198 @entity1 showed inhomogeneous perfusion. The mean value of CBF was (17    6) ml    @entity1009 )    100 g(-1) in 12 @entity385 @entity1 , (136    69) ml    @entity1009 )    100 g(-1) in 8 @entity198 @entity1 and (68    12) ml    @entity1009 )    100 g(-1) three in 20 healthy volunteers. The difference in mean value of CBF among the three groups was statistically significant (P < 0.01). CONCLUSION: Acute @entity385 often shows low perfusion and acute @entity198 shows high perfusion on 3D-pcASL images, which has a higher application value in diagnosis and differentiation of @entity385 and @entity198 .
