[Peripheral blood indicators of inflammatory response during the first twenty-four hours of XXXX ].

@entity1 @entity32 @entity2002 @entity64 @entity101 @entity6 @entity63 @entity310 @entity2806 @entity385
INTRODUCTION: Reports point to the significant role of inflammatory mechanisms in @entity64 . These mechanisms are activated in peripheral blood in response to acute @entity63 injury of cerebral tissues. The aim of this study was to determine whether peripheral inflammatory response to acute @entity63 of the nervous tissue develops during the first twenty-four hours of @entity385 . MATERIAL AND METHODS: We studied 53 @entity1 divided into three groups: 25 @entity1 with @entity385 , @entity101 , and/or @entity6 (group I); 17 @entity1 with @entity101 , and/or @entity6 but without @entity64 (group II); 11 young, healthy individuals (group III). @entity310 concentrations in peripheral blood were measured in each group using a sandwich enzyme-linked immunosorbent assay (ELISA). Other markers of @entity32 in peripheral blood--C-reactive protein, @entity2002 , and leukocyte count--were assayed as well. The results were analyzed in relation to age, gender, co-morbidities, and blood-brain barrier injury. RESULTS: @entity310 concentrations in peripheral blood of @entity64 @entity1 were similar as in the other two groups. No associations between @entity310 and other inflammatory parameters were found. Injury of the blood-brain barrier was not accompanied by a significant change in the concentration of @entity310 . CONCLUSION: No significant peripheral inflammatory response to @entity2806 develops during the first twenty-four hours of @entity385 . This finding suggests that early anti-inflammatory prevention protocols can be devised to limit further injury of @entity63 nervous tissue caused by activation of inflammatory processes.
