Abnormal @entity694 in XXXX .

@entity1 @entity1568 @entity3884 @entity11884 @entity1902 @entity577 @entity694 @entity1744
BACKGROUND: The cause of @entity1744 ( @entity1744 ) is unknown. It may follow @entity1902 and be associated with an abnormal gut flora and with food intolerance. Our study was designed to assess whether these factors were associated with @entity694 . METHODS: We carried out a crossover controlled trial of a standard diet and an exclusion diet matched for macronutrients in six female @entity1744 @entity1 and six female controls. During the final 72 h on each diet, faecal excretion of fat, @entity1568 , starch, and non-starch polysaccharide NSP was measured, and total excretion of @entity3884 and @entity577 collected over 24 h in a purpose-built 1.4 m3 whole-body calorimeter. Breath @entity3884 and @entity577 excretion were then measured for 3 h after 20 g oral @entity11884 . FINDINGS: The maximum rate of gas excretion was significantly greater in @entity1 than in controls (2.4 mL/min IQR 1.7-2.6 vs 0.6, 0.4-1.1). Although total gas production in @entity1 was not greater than in controls (median 527 mL/24 h IQR 387-660 vs 412, 234-507), @entity3884 production was higher (332, 318-478 vs 162, 126-217, p=0.009). In @entity1 , the exclusion diet reduced symptoms and produced a fall in maximum gas excretion (0.5 mL/min IQR 0.3-0.7). After @entity11884 , breath @entity3884 was greater on the standard than on the exclusion diet. INTERPRETATION: @entity694 , particularly of @entity3884 , is greater in @entity1 with @entity1744 than in controls, and both symptoms and gas production are reduced by an exclusion diet. This reduction may be associated with alterations in the activity of @entity3884 -consuming bacteria. Fermentation may be an important factor in the pathogenesis of @entity1744 .
