In vivo inhibition of XXXX around orthodontic brackets.

@entity3760 @entity1 @entity1547 @entity1388
@entity3760 around orthodontic appliances is a problem. Suboptimal oral hygiene, long intervals between appointments, and potentially poor @entity1 cooperation with using @entity1388 dentifrices and mouth rinses necessitate a compliance-free means of preventing @entity1547 . The hypothesis of this study was that @entity1388 released by glass ionomer cement inhibits the formation of @entity1547 around orthodontic brackets in vivo. Brackets were bonded on 2 first premolars in 21 randomized, consecutively selected @entity1 11 to 18 years old. Eleven test-group subjects were bonded with @entity1388 -releasing glass ionomer cement, and 10 control subjects were bonded with composite resin (no @entity1388 ). The teeth were extracted after 4 weeks, sectioned, and evaluated quantitatively by cross-sectional microhardness testing. @entity1388 levels in @entity1 saliva were measured by the Taves diffusion method in samples taken at days 0 (baseline), 1, 2, 3, 7, 14, 21, and 28 to determine whether @entity1388 from the glass ionomer cement influenced the overall intraoral @entity1388 levels. The results demonstrated significantly more @entity3760 around the brackets of the control @entity1 (P <.01, Wilcoxon signed rank test). For whole-mouth salivary @entity1388 levels, no significant overall difference between the groups (P >.05) and no noticeable trend within groups (P >.05) were found. These results indicate that using @entity1388 -releasing glass ionomer cement for bonding orthodontic brackets successfully inhibited caries in vivo. This cariostatic effect was localized to the area around the brackets and was statistically significant after 4 weeks.
