XXXX in South Africans of mixed ancestry: a retrospective analysis.

@entity1 @entity5 @entity320 @entity34
Little is known about the behaviour of @entity320 in @entity1 of mixed ancestry. A retrospective analysis of 844 consecutive @entity1 presenting with @entity320 over a 12-year period was performed. Forty @entity1 (4.8%) were of mixed ancestry. The data evaluated included @entity1 age, gender, delay in presentation, presenting stage, anatomical distribution, histology, management and outcome. The mean age at presentation was 52.8 years. Twenty-seven @entity1 were female. The mean delay in presentation was 1.54 years. Seventy per cent of @entity320 were confined to the extremities, of which one-third were plantar in origin. The most common histological variant, affecting 13 @entity1 (32.5%), was @entity320 ; 12.5% of @entity1 presented with in situ (Stage 0) disease, 17.5% with Stage I disease, 22.5% with @entity34 , 27.5% with @entity5 and 7.5% with Stage IV disease. Twenty-seven @entity1 (67.5%) remained alive at the end of the study after a median follow-up of 5.58 years, whilst 11 (27.5%) died after a median of 2.42 years. The median survival was 3.92 years. Although the histological type and anatomical distribution reflect the disease pattern of black populations, the overall 5-year survival of 74% is similar to that seen in white populations. An education programme is needed to improve @entity320 awareness in mixed race populations.
