A new simple prognostic score for @entity2835 : Albumin- XXXX (ALBI) score.

@entity1 @entity648 @entity409 @entity2835
BACKGROUND _ AIM: Serum albumin and @entity648 are the most significant independent prognostic factors to predict hepatic events in @entity1 with @entity2835 ( @entity2835 ). We aimed to investigate the prognostic significance of a new prognostic score, the albumin- @entity648 (ALBI) score, among @entity2835 @entity1 . METHODS: In a retrospective longitudinal cohort of 61 Chinese @entity2835 @entity1 with follow-up period up to 18.3 years, the prognostic performance of the ALBI in prediction of hepatic events was compared with other well-established prognostic scores: @entity1 -Pugh score, Model for End-stage @entity409 , Mayo risk score, Yale, European and Newcastle models. RESULTS: Fifteen @entity1 (24.6%) developed hepatic events during follow-up. The c-index (0.894) and   2 by likelihood ratio test (36.34) of the ALBI score were highest in comparison to other models. The ALBI score was the only independent prognostic factor by multivariate analysis and its adjusted hazard ratio of developing hepatic event was 27.8 (P<0.001). There were 3 prognostically different groups stratified by the ALBI score: ALBI grade 1 ( <=-2.60), grade 2 (>-2.60 to -1.39) and grade 3 (>-1.39) groups. The 2-year, 5-year and 10-years event-free survivals for grade 1, 2 and 3 groups were: 100.0% vs. 100.0% vs. 57.1%, 100.0% vs. 88.5% vs. 14.3%, and 100.0% vs. 81.7% vs. 0.0%, respectively (P<0.001). CONCLUSION: The ALBI score is readily derived from a blood test without using those factors evaluated subjectively or obtained by invasive procedures. It is an independent prognostic factor for @entity2835 @entity1 and provides better/similar prognostic performance compared to other prognostic scores.
