Factors Associated with Caregiver Burden in XXXX : 1-Year Follow-Up Study.

@entity1 @entity146 @entity303 @entity2146 @entity4943 @entity2414
OBJECTIVE: @entity303 symptoms (cognitive function, daily-living function, and @entity146 ) become more serious over time, which is likely to increase caregiver burden. The aim of this study is to investigate which @entity303 -related symptoms, and how the progression of these symptoms, have influenced caregiver burden during a 1-year follow-up assessment. METHODS: A total of 110 @entity1 with @entity303 were assessed for their cognitive function, daily-living function, and @entity146 . Caregivers were assessed for their caregiver burden. Bivariate analyses were conducted between caregiver burden and @entity303 @entity1 ' symptoms, in order to examine which particular symptoms were significantly associated with caregiver burden at the baseline. A multiple regression analysis was then conducted with each significantly associated variable with a view to identifying determinants, influencing caregiver burden. Additionally, bivariate analyses were conducted between the changes in caregiver burden and the changes in @entity1 ' symptoms, to investigate which @entity1 variable could best describe caregiver burden from baseline to the 1-year follow-up. A multiple regression analysis was conducted with each significantly-associated change in symptom, in order to identify determinants that influence a change in caregiver burden. RESULTS: Neuropsychiatric symptoms, such as @entity146 , aberrant motor-behavior, delusions and @entity4943 were found to be significant predictors of caregiver burden at baseline, according to multiple regression analysis. In addition, changes in @entity146 , such as delusions, @entity2146 and memory-related functioning in daily-living significantly predict a change in caregiver burden. CONCLUSION: Our results demonstrate that @entity146 and @entity2414 in daily-living functions are significant predictors of an increase in caregiver burden.
