Accuracy of on-bench biopsies in the evaluation of the histological subtype, grade, and @entity39 of XXXX .

@entity1637 @entity39 @entity5 @entity1358 @entity359 @entity652 @entity703
AIMS: Few data are available on the diagnostic accuracy of @entity703 biopsy. METHODS: We sought to evaluate morphological diagnostic accuracy--such as histotype, Fuhrman grading, and @entity39 --on a series of renal biopsies and matched whole @entity5 . RESULTS: Among 56 @entity703 , the benign instances consisted of six @entity1637 (10.7%), one @entity359 ( @entity359 ; 1.8%), and one @entity652 (1.8%). @entity5 consisted of @entity1358 ( @entity1358 ) in 37 cases (66.1%), papillary @entity1358 in six cases (10.7%), chromophobe @entity1358 in three cases (5.4%), and unclassified @entity1358 in one case (1.8%). Core biopsies were conclusive in 53 cases (94.6%), identifying six (10.7%) benign and 47 (83.9%) RCCs. The accuracy in identifying histological subtype was 92%, and the concordance between core biopsies and surgical specimens was nearly perfect (k = 0.858; p < 0.001). With regard to nuclear grade, the concordance index was only moderate (k = 0.253) and the concordance between core biopsies and surgical specimens was fair (k = 0.20; p = 0.11), such as for @entity39 . CONCLUSIONS: We concluded that the accuracy in identifying histological subtype is high. @entity5 with oncocytic features are the most problematic for diagnosis. Results for nuclear grades and coagulative @entity5 @entity39 are less convincing.
