Is routine pouch surveillance for @entity1141 indicated for XXXX ?

@entity1 @entity32 @entity5 @entity31 @entity1960 @entity4648 @entity1412 @entity2418 @entity30 @entity1141
PURPOSE: Isolated accounts of neoplastic pouch transformation suggest the need to perform routine ileoanal pouch surveillance with biopsy. These reports imply a model of @entity1141 to @entity5 . More recent reports studying "high risk" @entity31 @entity1 concluded that the development of @entity2418 is indeed a rare event. This study was designed to evaluate our institutional incidence of @entity1141 in ileoanal pouch during long-term follow-up. METHODS: A prospective database of all @entity1 undergoing ileoanal pouch construction (n = 767) was queried for all @entity1 undergoing pouch biopsy between 1983 and 2001. All @entity1 with @entity31 who underwent pouch biopsy were included. This excluded @entity1 with @entity30 , indeterminate @entity1960 , and @entity1412 . Pathology reports were reviewed for histologic evidence of @entity32 , atypia, @entity4648 , @entity1141 , or @entity5 . @entity1 age at biopsy, pouch age at time of biopsy, and pathology were analyzed. RESULTS: The @entity2418 of 160 @entity1 were surveyed with biopsies a total of 222 times. The average length of follow-up from pouch construction to time of surveillance and biopsy was 8.4 +/- 4.6 years. There were 83 @entity1 (52 percent) whose pouches were older than 10 years (mean, 12.7 +/- 2) at time of surveillance. With over 1,800 pouch-years of surveillance, only 1 @entity1 had focal, low-grade @entity1141 in the pouch. This @entity1 demonstrated no evidence of @entity1141 on further surveillance. CONCLUSION: Even with long-term follow-up of ileoanal pouch @entity1 , there is little evidence to support routine biopsy of the ileal mucosa in @entity31 @entity1 .
