The burden of mental health in XXXX .

@entity1 @entity6565 @entity308 @entity1032 @entity66 @entity11738 @entity4269 @entity3754 @entity1057 @entity4536 @entity7289 @entity1201
BACKGROUND: @entity1057 ( @entity1057 ) afflict around one billion individuals in the poorest parts of the world with many more at risk. @entity3754 is one of the most prevalent of the infections and causes significant morbidity in those who suffer the clinical conditions, particularly @entity4269 and hydrocele. @entity308 has been recognised as a prevalent disability in those with the disease because of the stigmatising nature of the condition. No estimates of the burden of @entity308 of any neglected @entity66 have been undertaken to date despite the recognition that such diseases have major consequences for mental health not only for @entity1 but also their caregivers. METHODS: We developed a mathematical model to calculate the burden of Disability- Adjusted Life Years (DALY) attributable to @entity308 in @entity3754 and that of their caregivers using standard methods for calculating DALYs. Estimates of numbers with clinical disease was based on published estimates in 2012 and the numbers with @entity308 from the available literature. RESULTS: We calculated that the burden of @entity308 in @entity6565 @entity1 was 5.09 million disability-adjusted life years (DALYs) and 229,537 DALYs attributable to their caregivers. These figures are around twice that of 2.78 million DALYs attributed to @entity6565 by the Global Burden of Disease study of 2010. CONCLUSIONS: @entity3754 and other neglected @entity66 , notably Buruli Ulcer, @entity4536 , @entity1201 , yaws, @entity7289 and @entity11738 cause significant co morbidity associated with @entity1032 in @entity1 . Studies to assess the prevalence of the burden of this co-morbidity should be incorporated into any future assessment of the Global Burden of neglected @entity66 . The prevalence of @entity308 in caregivers who support those who suffer from these conditions is required. Such assessments are critical for neglected @entity66 which have such a huge global prevalence and thus will contribute a significant burden of co-morbidity attributable to @entity1032 .
