Alteration of macromolecular events and elemental levels in the skin of UVC exposed hairless XXXX .

@entity72618 @entity19 @entity5 @entity219 @entity1372 @entity972 @entity68
Swiss @entity19 (S/RV/ @entity72618 -ba) were exposed to a spectral range of UV light emitting predominantly lambda 253.7 nm. Following a cumulative dose of 22.5 X 10(3) KJ/m2 @entity5 were induced. The @entity5 development occurred after 52 weeks, relatively a longer time interval following exposure, compared with shorter time intervals required for production of @entity5 in @entity19 by spectral range UVA and UVB as observed by other workers. A study of biochemical events viz. levels of protein, DNA, @entity219 , @entity68 , @entity1372 and @entity972 has been made in the skin samples of control and irradiated animals following ultraviolet irradiation with a dose of 22.5 X 10(3) KJ/m2. Study of macromolecular events in the skin of control and irradiated @entity19 , showed fluctuations in the levels of DNA. A particularly notable event is the occurrence of increased levels of DNA and @entity219 and their persistence during the 9-39 weeks post UV interval prior to @entity5 production. No such variation was observed in the control group in any of the intervals. Increased levels were also seen in case of @entity68 , @entity1372 and @entity972 at different intervals in the post UV periods. These fluctuations in various biochemical events are deemed to be indicative of UV initiated biochemical changes.
