@entity55 in @entity1641 induced by intrapulmonary inoculation of Streptococcus equi subsp. XXXX .

@entity1641 @entity548 @entity55 @entity39 @entity38443 @entity358 @entity11674
To evaluate the possibility that @entity11674 (S.z) the causative bacterial agent of @entity1641 @entity38443 (ESFP), as well as to investigate its pathogenesis, 10 @entity1641 (seven Thoroughbreds and three Anglo-Arab species, ranging from 2-4 years in age) were experimentally inoculated, via an endoscope, into bronchus of the lung lobe with a dose of 30 ml of 1-7 x 10(8) CFU/ml of S.z. After inoculation, autopsy and pathological examinations were sequentially conducted 30 min, 1, 2, 3, 4, 17, 20 hr and 2 weeks later. @entity55 induced by the intrapulmonary inoculation of S.z was characterized by small purulent pneumonic foci in the inoculated areas. With the lapse of time, these foci developed into @entity548 , @entity548 , and then purulent, coagulation @entity39 . These pathomorphological characteristics of experimental @entity55 closely resemble those naturally occurring ESFP. There is strong evidence that S.z. is implicated as a causal factor in ESFP. S.z. grew in the mucus, exudate, and pulmonary effusions. Further, the bacteria showed resistance against phagocytosis by @entity358 ( @entity358 ) and neutrophils. Inhibition of @entity358 and neutrophil function is considered to be important in the development of @entity55 . With the progression of the disease, the neutrophils often adhered to the endothelial surface of the alveolar capillary lumen and played a role in generating coagulation @entity39 of lung tissues.
