Ipsilateral Reduced Olfactory Bulb Volume in XXXX with Unilateral Nasal Obstruction.

@entity1 @entity8968
OBJECTIVES: To evaluate the effect of @entity8968 (by nasal polyps of different histopathology) on olfactory bulb volume using MRI technique. STUDY DESIGN: Cross-sectional study. SETTING: Tertiary university hospitals, Departments of Otolaryngology and Radiology. SUBJECTS AND METHODS: Eleven @entity1 with a few months of complete @entity8968 of different pathological etiologies were selected. MRI assessment of olfactory bulb volume was performed using planimetric manual contouring. The contralateral olfactory bulb was used as a comparative control for the same @entity1 . Eleven healthy controls constituted the control group. RESULTS: Mean olfactory bulb volume   SD of obstructed side = 14.3    3.7 mm(3), mean olfactory bulb volume   SD of nonobstructed side = 43.49    10.7 mm(3). The difference between the 2 sides was significant (P = .003). The difference in olfactory bulb volume between normal subjects and nonobstructed nasal side was statistically nonsignificant (t = .9118, P = .3727), while the difference between normal subjects' olfactory bulb volume and obstructed nasal side olfactory bulb volume in our @entity1 was extremely statistically significant (t = 9.7320, P < .0001). A strong negative correlation was found between duration of obstruction and olfactory bulb volume (R = -0.9761). CONCLUSION: This study shows that @entity8968 may be associated with a lateralized ipsilateral difference of olfactory bulb volume.
