Is the Complete Resection of XXXX in Adults Feasible Considering Both the Oncologic and Functional Outcomes?

@entity1 @entity227 @entity1640 @entity260 @entity4611 @entity976
OBJECTIVE: To assess the impact of the complete resection of @entity976 ( @entity976 ) in adults on oncologic and functional outcomes. METHODS: We retrospectively analyzed 82 @entity1 with @entity976 who were surgically treated by the same neurosurgeon at our institution between January 1994 and December 2012. RESULTS: Gross total resection (GTR) was achieved in 71 @entity1 (86.6%), near total resection (NTR) in 7 @entity1 (8.5%), and subtotal resection (STR) in 3 @entity1 (3.7%). The disease-specific overall survival rate was 100% with the exclusion of 2 surgery-related mortalities. The overall recurrence rate was 12.2% (10 of 82 @entity1 ), however the recurrence rate according to extent of resection (EOR) was 9.9% (7 of 71 @entity1 ) after GTR, 14.3% (1 of 7 @entity1 ) after NTR, and 66.7% (2 of 3 @entity1 ) after STR. The overall recurrence-free survival (RFS) rates at 5 and 10 years were 87.0% and 76.8%, respectively. Postoperatively, most @entity1 (86.3%) needed hormone replacement for at least 1 hypothalamic-pituitary axis. Vision improved in 56.4% of the @entity1 with @entity227 , but deteriorated in 27.4% of @entity1 . @entity1640 developed in 32.9% of @entity1 . There were no significant differences in the risks of @entity4611 , @entity227 , or @entity1640 between the groups with complete vs. incomplete removal. The overall rate of @entity260 was 22.0%, which did not differ between groups (p=0.053). CONCLUSION: The complete removal of a @entity976 at first surgery can provide a chance for a cure with acceptable morbidity and mortality risks.
