Phase-resolved Doppler Optical Coherence Tomographic Features in XXXX .

@entity1 @entity455 @entity2479 @entity1713 @entity3194 @entity941 @entity989 @entity5995
PURPOSE: To study @entity1 diagnosed with @entity2479 ( @entity2479 ) based on conventional imaging techniques with phase-resolved Doppler optical coherence tomography (OCT) to detect and localize blood flow in @entity989 ; and to compare these findings to conventional imaging, which are mostly invasive and give limited information concerning intra- and transretinal blood flow. DESIGN: Single-center, consecutive observational case series. METHODS: Twelve treatment-na  ve @entity1 diagnosed with @entity2479 based on fundus examination, @entity941 angiography, and @entity3194 angiography were included. Median age was 79 years (range 65-90). @entity1 were imaged with an experimental 1040  nm swept-source phase-resolved Doppler OCT instrument. Abnormal flow was defined as intraretinal neovascularization or @entity989 . RESULTS: In 11 @entity1 adequate phase-resolved Doppler OCT images were obtained showing @entity989 . In 4 @entity1 a @entity989 was found, 3 @entity1 showed intraretinal neovascularization connected with a @entity1713 , 2 @entity1 showed only intraretinal neovascularization, and in 2 @entity1 flow was limited to the subretinal or sub-retinal pigment epithelial space. CONCLUSIONS: Phase-resolved Doppler OCT is able to detect and localize abnormal @entity989 . Blood flow was mostly confined to the intraretinal structures with or without a connecting @entity1713 ; in one-third of @entity1 a @entity989 was detected. The potential of angiography with phase-resolved Doppler OCT to accurately distinguish between normal and pathologic blood flow in addition to structural OCT data without invasive procedures will help to further elucidate both @entity5995 and  @entity455 like @entity2479 .
