Closure of Isolated XXXX : Long-Term Outcomes and Rate of Re-intervention.

@entity1 @entity453 @entity204 @entity583
UNASSIGNED: Long-term outcome after closure of isolated @entity453 (ICCAF) is poorly documented. To assess late outcome after ICCAF closure, a 1983-2013 retrospective study included all @entity1 who attempted an ICCAF closure and whose follow-up was >= 1  year. ICCAF was diagnosed in 23 @entity1 [median age 6.9  years (0.1-70.5  years), 13 @entity1 ]. ICCAF was symptomatic in 12 @entity1 (52.2  %). First intervention was either a transcatheter embolization (n  =  19 @entity1 , 82.6  %) or a surgical ligation (n  =  4 @entity1 , 17.4  %). After a follow-up of 9.0  years (2.8-33.5), neither @entity204 nor late ischemic event occurred but one @entity1 was transplanted, because of postoperative @entity583 . Late ICCAF recanalization occurred in eight @entity1 , leading to successful embolization of the shunt in all @entity1 after a delay of 9.8  years (5.7-13.8  years) from the first intervention. Re-intervention occurred later in @entity1 (p  =  0.0027), with a 50 and 37.5  % freedom from re-intervention in adults compared to a 100 and 89.0  % in @entity1 , respectively, at 1 and 6  years of follow-up. At last follow-up, coronary artery diameter had decreased from a mean z score of 12.0      7.7 to a mean z score of 6.0      6.0 (p  =  0.002). Long-term outcome after ICCAF closure is excellent, with neither @entity204 nor late ischemic event, and a significant decrease in coronary artery diameter with time. Late follow-up is of paramount importance, as one-third of @entity1 will require a re-intervention for late shunt recanalization.
