Functional polymorphism of XXXX ( @entity1495 ) gene is not associated with @entity161 and with its deficit subtype.

@entity1 @entity1479 @entity15606 @entity191 @entity51 @entity161 @entity1495 @entity214
BACKGROUND: The deficit subtype of @entity161 is hypothesized to constitute a pathophysiologically distinct subgroup of @entity161 @entity1 suffering from enduring, @entity191 and various @entity51 . Matrix metalloproteinases (MMPs) are extracellularly acting endopeptidases the substrates of which are matrix and adhesion molecules. Recently, @entity1495 has been shown to be involved in various forms of synaptic plasticity, learning and memory consolidation. The primary aim of the present study was to evaluate associations between the functional @entity1495 @entity15606 gene polymorphism and the deficit and @entity51 subtypes of @entity161 . METHODS: The study was conducted between 2009 and 2012. Deficit @entity161 was diagnosed using the @entity214 . The sample consisted of 468 @entity1 , Caucasians, of Polish descent with @entity1479 10 diagnosis of @entity161 : 189 [51% males] were included in a @entity51 subgroup, 279 @entity1 [53% males] were included in a deficit subgroup. The control group consisted of 532 subjects, Caucasians, of Polish descent [51% males]. @entity1495 @entity15606 gene polymorphism was genotyped using the fluorescence resonance energy transfer (FRET) method and the Light Cycler System 2.0. RESULTS: The frequencies of genotypes and alleles did not differ between the @entity161 @entity1 and control group. The deficit and @entity51 @entity1 did not differ in terms of the genotype and allele frequencies. No differences were found in genotype and allele frequencies between the deficit @entity1 and the controls and between the @entity51 @entity1 and the controls. CONCLUSION: We found no evidence for the association between the functional @entity1495 @entity15606 gene polymorphism and deficit/ @entity51 subtypes of @entity161 .
