[Surgical stress in XXXX with asymptomatic @entity438 ].

@entity1 @entity1851 @entity2337 @entity190 @entity439 @entity130 @entity438
BACKGROUND: Surgical stress elicits a characteristic response involving induction of synthesis and release of acute-phase proteins such as @entity1851 ( @entity1851 ). To objectively evaluate the surgical stress in @entity1 with asymptomatic @entity438 , serum levels of @entity1851 after direct clipping via the pterional approach were measured. METHODS: 42 @entity1 who experienced an uneventful postoperative course, were evaluated according to age (less or more than 65 years old [adult or elderly]), aneurysmal location (middle cerebral artery territory [MC], anterior communicating artery [Acom] or internal carotid artery territory [ @entity2337 ]) and intraoperative @entity130 (positive or negative). We defined intraoperative @entity130 as intentional vein cutting, perforator vessel injury or suction of the gyrus rectus. All @entity1 received standardized general anesthesia and were treated after the operations according to our standard protocols. Serum levels of @entity1851 on postoperative day 2 were compared in each category. RESULTS: Serum levels of @entity1851 showed no significant difference between the adult group and the elderly group, but were greater in Acom @entity1 than in MC and @entity2337 @entity1 (p < 0.01, p < 0.05). As to intraoperative @entity130 , the positive group (almost all were intentional vein cutting) showed greater @entity1851 levels than the negative group in MC and @entity2337 @entity1 (p < 0.05). Operation time and volume of @entity190 were almost the same in each category. CONCLUSION: Our study shows that as far as serum levels of @entity1851 are concerned, Acom location and vein cutting are the main factors of surgical stress in cases of @entity439 .
