Preoperative Neutrophil-to-Lymphocyte Ratio as Prognostic Predictor for XXXX after Radical Resections.

@entity1 @entity957 @entity455
OBJECTIVES: @entity957 ( @entity957 ) is an aggressive disease in the head and neck region. Therefore, simple and useful prognostic predictors of @entity957 are needed for clinical practice. This study investigates the prognostic significance of preoperative neutrophil-to-lymphocyte ratio (NLR) in @entity1 with @entity957 who received radical resections. METHODS: Retrospective review was conducted on medical records at a tertiary referral hospital involving 146 consecutive @entity1 who underwent radical resection for @entity957 between January 2000 and December 2010. The prognostic significance of NLR and other clinicopathologic factors was analyzed. The relationships between the NLR value and clinicopathologic factors were also evaluated. RESULTS: The study cohort consisted of 146 @entity1 with @entity957 , with a mean age of 57.5 years (range, 34-89 years). The median number of NLR was 2.28 (range, 0.71-8.75). On the basis of this median value, the cutoff value of NLR was set as 2.3. The @entity1 were divided into 2 groups: a low (<2.3) NLR group and a high (>= 2.3) NLR group. @entity1 with NLR of 2.3 or more had significantly higher incidence of wound complications (P = 0.026). The 3-year overall survival rate was 69.9% in @entity1 in the low NLR group and 27.4% in those in the high NLR group (P <0.001; hazard ratio;2.99; 95% confidence interval, 1.91-4.67). CONCLUSIONS: Results showed that high preoperative NLR is associated with @entity455 and poor survival in @entity1 with @entity957 .
