Morphometry of the XXXX in long-term survivors of childhood @entity130 .

@entity1 @entity131 @entity409 @entity4611 @entity854 @entity2339 @entity130
PURPOSE: Chronic @entity4611 is increasingly recognized as a sequela of @entity131 ( @entity131 ). Our aim was to rule out any late morphometric changes of the @entity4611 in survivors of @entity131 during childhood requiring intensive care. METHODS: We assessed morphometric @entity854 region and @entity2339 in @entity1 who sustained @entity131 during childhood. The @entity1 showed no clinical hormonal dysfunction at the acute phase and pituitary hormone levels at the time of our study were within normal limits. From the 18 enrolled @entity1 in the magnetic resonance study, five were removed due to morphological changes or anatomical variations. We studied the MRI of 13 male survivors (mean age 27 years, mean time after @entity130 20 years) and compared them to 13 male control subjects who were matched in terms of age (mean age, 26 years), education and ethnicity. Analyses of the @entity4611 on a midsagittal T2- and T1-weighted image were performed. We used voxel-based morphometry (VBM), an unbiased MRI morphometric method to investigate hypothalamic region in this group of @entity1 . RESULTS: There was only a trend towards a reduced @entity4611 in the @entity1 group compared to controls. However, no significant morphological and morphometric abnormality was seen and VBM showed no hypothalamic grey matter loss. CONCLUSION: In the @entity409 , no persisting morphometric changes of the @entity4611 were seen in survivors of childhood @entity131 requiring intensive care.
