Correlation analysis of two serum-specific immunoglobulin E test systems and skin-prick test in XXXX @entity1 from northeast China.

@entity1 @entity7130 @entity2023 @entity272
BACKGROUND: @entity272 ( @entity272 ) is the most common screening method for allergy evaluation. The detection of serum-specific immunoglobulin E (sIgE) is also commonly used. The sensitivity and specificity of these testing methods may vary due to type of causative allergen and type of allergic manifestation. The purpose of this study was to evaluate the correlation between two methods of measuring sIgE (AllergyScreen [Mediwiss Analytic GmbH, Moers, Germany] and ImmunoCAP [Pharmacia, Uppsala, Sweden]) and @entity272 for the diagnosis of @entity2023 ( @entity2023 ). METHODS: All 216 @entity1 who were referred to the allergist for suspected @entity2023 from June to October 2009 had @entity272 and the two serological tests. One hundred fifty-eight @entity1 had a positive clinical history and a related positive @entity272 . The @entity272 was used as reference standard, and we selected three allergens ( @entity7130 , mugwort, and ragweed), which were common in fall in northeast China, to analyze the correlation of the two serum tests and @entity272 . RESULTS: Compared with the @entity272 , the diagnostic indexes (accuracy, sensitivity and specificity) of the AllergyScreen system and the ImmunoCAP system were 0.819 versus 0.810, 0.780 versus 0.872, and 0.862 versus 0.741, respectively. The accuracy was similar between the two systems (p > 0.05). The ImmunoCAP system method had a higher sensitivity (p < 0.01). The AllergyScreen system had a higher specificity (p < 0.01). CONCLUSION: These data support that the AllergyScreen system and ImmunoCAP system can identify potentially significant allergens in the diagnosis of @entity2023 in @entity1 from northeastern China.
