Abnormal thallium kinetics in XXXX of the aorta: evidence for diffuse hypertension-induced vascular pathology.

@entity1 @entity455 @entity4214 @entity1498 @entity2026 @entity854 @entity86 @entity741 @entity1317 @entity453 @entity65
After operative correction of @entity1498 , @entity1 continue to have excess @entity65 , including manifestations of @entity741 . Previous morphologic studies support the concept of direct hypertensive @entity1317 in these @entity1 . To determine whether abnormalities of myocardial perfusion were present in an asymptomatic group of @entity1 with @entity1498 repair, 18 @entity1 and 9 @entity1 with a mean age of 26 years (range 19 to 41) were studied between 2 and 25 years after operative correction. Stress electrocardiography and quantitative thallium imaging by a circumferential profile technique were used. These @entity1 were compared with a normal group, statistically defined as having a less than 1% prevalence of significant obstructive @entity453 . The @entity86 group demonstrated a @entity2026 redistribution in each view analyzed. As compared with findings in the control subjects, thallium washout in the anterior view (41.9 versus 48.6%, p = 0.02) and left anterior oblique projection (40.5 versus 48.2%, p = 0.007) was significantly diminished. Although the @entity86 group had a lower @entity4214 redistribution rate in the lateral view (41.4 versus 46.3%, p = 0.09) this difference did not reach statistical significance because of the intrinsic variability of this projection. Plots of the median percent thallium washout revealed independence from circumferential profile angle, indicating @entity854 in perfusion. No correlation between clinical variables and thallium kinetics could be established, suggesting marked individual variability in the development of this @entity455 . The observation of abnormal thallium kinetics in @entity1 with @entity1498 repair may have consequences for long-term follow-up and therapy.
