Incidence Trends and Geographical Variability of Pediatric XXXX in Slovenia: A Nationwide Study.

@entity1 @entity31 @entity29 @entity8787 @entity30
Background. The aims of the study were to determine the incidence rate of pediatric @entity29 (PIBD) and its trends for the period of 2002-2010 and to assess the geographical distribution of PIBD in Slovenia. Materials and Methods. Medical records of @entity1 (0-18 years) with newly diagnosed @entity8787 during the study period were retrospectively reviewed. Results. The mean incidence rate for @entity8787 in 2002-2010 was 7.6 per 100,000 @entity1 and adolescents per year, 4.5 for @entity30 ( @entity30 ), 2.9 for @entity31 ( @entity31 ), and 0.2 for @entity8787 -unclassified, respectively. The incidence rate increased from 5.8 per 100,000 per year in 2002-2004 to 8.6 in 2005-2007 and remained stable afterwards. Statistically significant difference in the incidence rate between the Northeastern and Southwestern parts of the country was observed (p = 0.025). Conclusion. This nationwide study demonstrates that Slovenia is among the European countries with the highest PIBD incidence. During the study period a substantial rise of PIBD incidence was observed during the first half of the study and it seems to have stabilized in the second half. The significant difference in PIBD incidence between Northeastern and Southwestern parts of the country merits further exploration of the possible environmental factors.
