Association between serum soluble XXXX and hyperglycaemia: a cross-sectional study among Chinese adults.

@entity1 @entity13381 @entity413 @entity6
OBJECTIVES: Decreased natriuretic peptides are risk factors for @entity6 . As a physiological activator of natriuretic peptides, @entity13381 may play a role in @entity413 metabolism. Here, we aimed to test the hypothesis in a general population of China. DESIGN: Cross-sectional study. SETTING: A population study in Suzhou, China. @entity1 : A total of 2498 @entity1 aged above 30   years were included in the study. OUTCOME MEASURES: The association between serum soluble @entity13381 and hyperglycaemia was examined in @entity1 and @entity1 , using non-conditional logistic regression models, respectively. RESULTS: Serum soluble @entity13381 , in @entity1 and @entity1 , was significantly higher in @entity1 with hyperglycaemia than in those without (all p<0.001). OR of hyperglycaemia positively and significantly increased with serum soluble @entity13381 quartiles, in @entity1 (p for trend <0.001) and in @entity1 (p for trend=0.050), even after multivariate adjustment. @entity1 with a serum soluble @entity13381 , in @entity1 (OR=1.66, 95% CI 1.24 to 2.23) and @entity1 (OR=1.27, 95% CI 1.00 to 1.61), over the median level, were more likely to have hyperglycaemia compared with the remaining @entity1 , after controlling for confounding factors. CONCLUSIONS: Hyperglycaemia was significantly and positively associated with increased serum soluble @entity13381 in @entity1 and @entity1 . Our findings suggest that serum soluble @entity13381 may be a risk factor or a biomarker of hyperglycaemia.
