XXXX in perinatal and childhood @entity4008 .

@entity1 @entity410 @entity4008 @entity1276 @entity16 @entity2260 @entity1188 @entity5746 @entity880 @entity328 @entity385
BACKGROUND: @entity385 is an important @entity16 of childhood @entity4008 , but little is known about its epidemiology and outcomes. AIM: To determine the predictive factors, clinical features, causative pathogens, and outcomes of @entity385 secondary to perinatal and childhood @entity4008 . DESIGN: Retrospective analysis METHODS: Over the period 1986-2001, 166 perinatal and childhood @entity1 were identified as having culture-proven @entity4008 , of whom 14 had @entity385 at admission. The clinical and CSF data of @entity1 with and without @entity385 on admission were compared. RESULTS: @entity385 @entity1 accounted for 10% (14/166) of @entity4008 , mostly in the first year of life (11/14, 79%). @entity5746 species (n = 4) and @entity328 (n = 4) were the most frequent causative pathogens, accounting for 57% (8/14) of episodes. Single @entity1188 were found in four @entity1 and multiple @entity1188 in 10. At 1 year follow-up, outcome was good in three, but poor in 11. Significant differences between the two @entity1 groups at admission included age bands, presence of @entity410 , @entity1276 , disturbed consciousness on admission, and CSF @entity880 concentration. DISCUSSION: There was a high prevalence of @entity385 when the disease was caused by @entity2260 and @entity5746 species. Occurrence was highest in the first year of life, and the prognosis in this @entity1 group is poor. Risk factors associated with @entity385 in our @entity1 included age 28-365 days, @entity410 , @entity1276 , disturbed consciousness on admission, and high CSF @entity880 concentrations.
