Adhesio interthalamica alterations in XXXX : A systematic review and meta-analysis.

@entity1 @entity75 @entity72 @entity161 @entity15838
Magnetic resonance imaging (MRI) studies have reported a variety of @entity75 in association with @entity161 . These include a higher prevalence of an absent adhesio interthalamica (AI; also known massa intermedia), a gray matter junction that is present between the two thalami in approximately 80% of healthy subjects. In this meta-analytic review, we describe and discuss the main AI MRI findings in @entity72 ( @entity72 ) to date. The MEDLINE and ISI Web of Knowledge databases were searched up to December 2010, for studies that used MRI to assess AI in @entity1 with @entity15838 and controls. From fourteen potential reports, eleven were eligible to be part of the current review. These studies included 822 @entity1 with @entity15838 and 718 healthy volunteers. There was a large degree of variability in the MRI methods they employed. @entity1 with @entity15838 had a higher prevalence of absent AI than healthy volunteers (odds ratio = 1.98; 95% confidence interval 1.33-2.94; p = 0.0008). This association was evident in both male and female @entity15838 subjects, and there was no evidence that the prevalence was related to age or duration of illness. The significance of the absence of an AI for @entity15838 may be clarified by studies in large, longitudinal community-based samples using standardized methods.
