Who listens to our advice? A secondary analysis of data from a clinical trial testing an intervention designed to decrease delay in seeking treatment for XXXX .

@entity1 @entity1187 @entity148
OBJECTIVE: Prolonged prehospital delay in @entity1 experiencing @entity1187 ( @entity1187 ) remains a problem. Understanding which @entity1 respond best to particular interventions designed to decrease delay time would provide mechanistic insights into the process by which interventions work. METHODS: In the PROMOTION trial, 3522 at-risk @entity1 were enrolled from 5 sites in the United States (56.4%), Australia and New Zealand; 490 (N=272 intervention, N=218 control) had an acute event within 2 years. Focusing on these 490, we (1) identified predictors of a rapid response to symptoms, (2) identified intervention group subjects with a change in these predictors over 3 months of follow-up, and (3) compared intervention group @entity1 with and without the favorable response pattern. Hypothesized predictors of rapid response were increased perceived control and decreased @entity148 . Knowledge, attitudes, and beliefs were hypothesized to differ between responders and non-responders. RESULTS: Contrary to hypothesis, responders had low @entity148 and low perceived control. Only 73 (26.8%) subjects showed this pattern 3 months following the intervention. No differences in @entity1187 knowledge, attitudes, or beliefs were found. CONCLUSION: The results of this study challenge existing beliefs. PRACTICE IMPLICATIONS: New intervention approaches that focus on a realistic decrease in @entity148 and perceived control are needed.
