Contemporary Management and Control of Uncomplicated XXXX in Canada: Insight From the Primary Care Audit of Global Risk Management (PARADIGM) Study.

@entity1 @entity101 @entity6 @entity2299 @entity7774 @entity1144 @entity209 @entity65
BACKGROUND: Although clinical practice guidelines for the management of @entity101 exist in Canada, the rate of contemporary blood pressure (BP) control remains unclear. METHODS: In the Primary Care Audit of Global Risk Management (PARADIGM) study, 3015 healthy, middle-aged Canadians, free of @entity65 ( @entity65 ) or @entity6 were evaluated. In this analysis, we characterized the @entity65 risk factors, treatment patterns, and BP control rates in subjects with uncomplicated @entity101 . RESULTS: A total of 917 subjects (30.4%) had a diagnosis of @entity101 . The median age was 59    8 years. The mean treated systolic/diastolic BP were 134    14 mm Hg/82    9 mm Hg, respectively. @entity65 risk factors included past/current smoking (35.9%), @entity1144 (62.5%), and @entity2299 (59.4%). Using the Framingham Risk Score, 20.4%, 41.0%, and 38.5% of the subjects were at low, intermediate, and high risk, respectively. Of the 88% with treated @entity101 , 46.9%, 38.7%, and 14.3% received 1, 2, or >= 3 drugs, respectively. The rate of BP control was 57.4% (systolic BP < 140 and diastolic BP < 90 mm Hg). The rate of BP control was lower in @entity1 prescribed diuretic monotherapy (53.2%) vs those who received @entity7774 converting enzyme inhibitor/angiotensin receptor blocker monotherapy (66.5%; P < 0.01). Importantly, BP control deteriorated with increasing Framingham Risk Score, and was lower in @entity1 with @entity209 vs those without (P < 0.00001 for both). CONCLUSIONS: PARADIGM demonstrated that @entity65 risk factors are prevalent in Canadians with uncomplicated @entity101 . BP control was modest (57.4%) and was lowest in @entity1 prescribed diuretic monotherapy and in those at highest @entity65 risk. Despite the success of national @entity101 strategies, enhanced efforts are warranted to improve BP control in Canada.
