XXXX or @entity12863 impregnation of urinary catheters has a minimal effect on uropathogen adherence.

@entity12863 @entity575 @entity797 @entity1346 @entity293 @entity526
PURPOSE: Bacterial adherence to the urinary catheter is an early step in biofilm formation and the pathogenesis of catheter associated @entity293 . We studied in vitro the effect of @entity575 or @entity12863 impregnation of urinary catheters on uropathogen ability to adhere to urinary catheters. MATERIALS AND METHODS: We studied commercially available @entity12863 - @entity1346 , @entity1346 only, @entity575 - @entity1346 -hydrogel, @entity1346 -hydrogel, @entity575 -latex-hydrogel and latex-hydrogel catheters. Catheters were incubated in sterile broth for 0, 3, 5, 7 and 10 days, respectively, before inoculation and overnight incubation with @entity526 or @entity797 . RESULTS: Adherence of @entity526 and @entity797 to @entity12863 catheters was significantly decreased compared to that of @entity1346 -only catheters when catheters were fresh. The anti-adherence effect of @entity12863 on @entity526 decreased with time but was still significant at 5 days. For @entity797 the effect of @entity12863 was lost by 3 days of pre-incubation. @entity526 adherence was not significantly decreased on @entity575 impregnated catheters compared to that on control catheters of the same base material. @entity575 was associated with a significant decrease in @entity797 adherence to latex-hydrogel catheters but not to @entity1346 -hydrogel catheters. The adherence of each species to @entity1346 catheters with hydrogel was significantly lower than that to @entity1346 -only control catheters. CONCLUSIONS: @entity575 impregnation had little effect on bacterial adherence in our model and @entity12863 impregnation had a significant effect only for the first 5 days. Our results do not support a role for @entity575 urinary catheters to prevent catheter associated @entity293 by decreasing bacterial adherence.
