Pancreatoduodenectomy in the treatment of XXXX .

@entity1 @entity6 @entity167 @entity1689 @entity204 @entity356
The value of surgical resection for @entity1 with @entity1689 has been debated on account of persistent symptoms and the morbidity of the operative procedure, both immediate and delayed. This paper explores the consequence of pancreatoduodenectomy in 175 @entity1 with @entity1689 who were operated on between 1976 and 1997. All @entity1 were carefully selected after varying periods of conservative management. The operation was a classical Kausch-Whipple resection in 98 @entity1 and a pylorus-preserving procedure in 67. There were four postoperative @entity204 (days 7, 10, 35, and 70), and only two reoperations were performed. The median number of postoperative events was one, with delayed @entity356 being the most common (31 @entity1 ). The median length of in-hospital stay was 20 days (range: 8-215 days), but no @entity1 was discharged until medical and social disabilities were resolved. There were seven late @entity204 , most of them linked to cigarette smoking and @entity167 consumption; 75% of @entity1 had a good clinical outcome, but 18 @entity1 required further pancreatic surgery at a mean of 12 months, either a pancreatojejunostomy or a completion pancreatectomy. @entity6 occurred in 40% of @entity1 by 5 years, and most, at some stage of their postoperative period, required pancreatic enzyme supplementation. It is suggested that resection of the pancreas provides a reasonable life-style in 75% of @entity1 , but the outcome depends in large part on the predisposing disease.
