Comparison of sonoelastography guided biopsy with systematic biopsy: impact on XXXX detection.

@entity75 @entity1 @entity263 @entity5
A prospective study was performed to determine the value of sonoelastography (SE) targeted biopsy for @entity263 ( @entity263 ) detection. A series of 230 male screening volunteers was examined. Two independent examiners evaluated each subject. One single investigator performed < or =5 SE targeted biopsies into suspicious regions in the peripheral zone only. The stiffness of the lesion was displayed by SE and color-coded from red (soft) to blue (hard). @entity75 were considered as malignant and targeted by biopsy. Subsequently, another examiner performed ten systematic biopsies. @entity5 detection rates of the two techniques were compared. @entity5 was detected in 81 of the 230 @entity1 (35%), including 68 (30%) by SE targeted biopsy and in 58 (25%) by systematic biopsy. @entity5 was detected by targeted biopsy alone in 23 @entity1 (10%) and by systematic biopsy alone in 13 @entity1 (6%). The detection rate for SE targeted biopsy cores (12.7% or 135 of 1,109 cores) was significantly better than for systematic biopsy cores (5.6% or 130 of 2,300 cores, P < 0.001). SE targeted biopsy in a @entity1 with @entity5 was 2.9-fold more likely to detect @entity263 than systematic biopsy. SE targeted biopsy detected more cases of @entity263 than systematic biopsy, with fewer than half the number of biopsy cores in this prostate-specific antigen screening population.
