Smooth Muscle Cells of Penis in the XXXX : Noninvasive Quantification with Shear Wave Elastography.

@entity35 @entity1918 @entity3145
Purpose. Smooth muscle cells (SMCs) of cavernosum play an important role in erection. It is of great significance to quantitatively analyze the level of SMCs in penis. In this study, we investigated the feasibility of shear wave elastography (SWE) on evaluating the level of SMCs in penis quantitatively. Materials and Methods. Twenty healthy male @entity35 were selected. The SWE imaging of penis was carried out and then immunohistochemistry analysis of penis was performed to analyze the expression of @entity1918 in penis. The measurement index of SWE examination was @entity3145 ( @entity3145 ). The measurement index of immunohistochemistry analysis was positive area percentage of @entity1918 (AP). Results. Sixty sets of data of @entity3145 and AP were obtained. The results showed that @entity3145 was significantly correlated with AP and the correlation coefficient was -0.618 (p < 0.001). The result of @entity3145 had been plotted against the AP measurements. The relation between the two results has been fitted with quadric curve; the goodness-of-fit index was 0.364 (p < 0.001). Conclusions. The level of SMCs in penis was successfully quantified in vivo with SWE. SWE can be used clinically for evaluating the level of SMCs in penis quantitatively.
