XXXX in pancreas transplant recipients.

@entity1 @entity2803 @entity6 @entity281 @entity364 @entity1320 @entity526
During a 7-year period, 116 pancreas transplants were performed in 98 @entity6 @entity1 (49 with and 49 without previous kidney transplants) at the University of Minnesota. The posttransplant clinical course of 26 recipients (22%) was complicated by an @entity1320 (8 with and 18 without previous kidney transplants). Infections occurred in 19/57 cases (33%) in which exocrine secretions were managed by enteric drainage, in 5/15 cases (33%) managed by free drainage into the peritoneal cavity, in 1/39 cases (3%) in which the duct was injected with a synthetic polymer, and in 1/2 cases (50%) in which a pancreaticocystostomy was performed. The organisms @entity526 , enterococci, bacteroides, and several anaerobes were cultured from the @entity1 with enteric drainage, while staphylococci were associated with the open duct drainage. @entity364 with Candida were found with all techniques. Surgical and percutaneous drainage was performed in all @entity1 . In 14 @entity1 , functioning and, in four @entity1 , nonfunctioning grafts were removed. In five @entity1 , the @entity281 resolved while the grafts were functioning, and these @entity1 are currently alive and well. Seven of the 26 @entity1 with @entity281 died (27% mortality rate), five after graft removal and two with the graft still in place (1 with and 1 without function), five in the open-duct, and one each in the enteric and urinary drainage categories. In the 90 cases without @entity1320 , only six @entity1 died (4 cardiovascular, 1 anaphylaxis, 1 @entity2803 ), for a mortality rate of 7%.
