Radiation-induced XXXX with rapid malignant transformation: case report.

@entity1 @entity66 @entity1276 @entity5 @entity11 @entity816 @entity2903 @entity2287
A 23-year-old @entity1 was admitted with a rare case of radiation-induced @entity816 manifesting as 3-month history of unstable gait. He had received 50 Gy of irradiation therapy for a germ cell @entity5 in the right basal ganglia 13 years earlier. Magnetic resonance (MR) imaging on admission showed a non-enhanced @entity66 in the right cerebellar hemisphere with expansion to the vermis. The histological diagnosis of the stereotaxic biopsy specimen was grade II @entity816 . Two months later, he developed drowsiness, and MR imaging demonstrated that the @entity5 had enlarged and was enhanced after @entity2287 injection. The clinical diagnosis was high-grade @entity11 resulting from malignant transformation. The @entity5 had compressed the mesencephalic aqueduct, leading to obstructive @entity1276 . Endoscopic third ventriculostomy was performed to improve the cerebrospinal fluid circulation. He underwent chemotherapy with @entity2903 postoperatively, but died 8 months after the initial diagnosis of @entity816 . The clinical course of radiation-induced @entity816 is not benign. The potential for malignant transformation necessitates careful postoperative follow up for @entity1 with this @entity5 .
