Relationship between pattern of intracranial @entity7244 on transcranial doppler and Oxfordshire @entity64 Project clinical classification of XXXX .

@entity1 @entity64 @entity24603 @entity7244 @entity450 @entity1504 @entity1188 @entity432 @entity850 @entity385
BACKGROUND AND PURPOSE: The Oxfordshire @entity64 Project (OCSP) devised a simple classification for acute @entity64 based on clinical features only, which is of value in predicting prognosis. We investigated whether the pattern of @entity1504 is related to the clinical syndrome. METHODS: @entity1 with acute @entity385 were classified by a @entity64 physician as having total or partial anterior circulation @entity1188 ( @entity24603 or PACI, respectively), @entity1188 ( @entity1188 ), or posterior circulation @entity1188 (POCI). Color-coded power transcranial Doppler was done whenever possible. Intracranial arterial velocities were compared in the 4 subtypes of @entity385 after adjustment for age and time to transcranial Doppler. RESULTS: Middle cerebral artery velocity was abnormal ( @entity450 , reduced velocity, @entity432 , or focal @entity850 ) in 38 of 69 TACIs (55%), 50 of 171 PACIs (29%), and 20 of 236 LACIs or POCIs (8%) (P<0.001). Velocity in the A1 segment of the anterior cerebral artery was reversed in 12 of 69 TACIs (17%), 20 of 171 PACIs (12%), and 8 of 236 LACIs or POCIs (3%) (P<0.001). Basilar artery velocity was abnormal in 8 of 121 POCIs (7%) compared with 5 of 355 (1%) of the other subtypes (P=0.005). Vertebral artery velocity was abnormal (reduced velocity, @entity432 , @entity850 ) in 20 of 121 POCIs (17%) compared with 20 of 355 others (6%) (P=0.01). CONCLUSIONS: Intracranial @entity7244 were related to OCSP clinical subtype. Therefore, it is possible to stratify @entity1 according to OCSP classification in trials of new treatments in which treatment effectiveness may depend on the underlying pattern of arterial pathology and before any arterial imaging is available.
