Nosocomial blood stream infections in a neonatal intensive care unit in Ankara, XXXX .

@entity1 @entity801 @entity295 @entity796 @entity233 @entity114 @entity5898 @entity4509 @entity3524 @entity2893 @entity4005 @entity869 @entity3402
Nosocomial blood stream infections continue to be a cause of high mortality and morbidity in newborn intensive care units (NICUs). Identification of the causative microorganisms and their antimicrobial sensitivities will guide the selection of appropriate empirical treatment. We prospectively evaluated culture-proven @entity295 cases and antibiotic sensitivity patterns seen in the NICU of Dr. Sami Ulus @entity1 's Hospital, in Ankara, @entity233 during a six-year period (2000-2006). A total of 106 @entity295 attacks were found in 100 @entity1 , with 72 of them preterm. Gram-negative bacteria were isolated at a rate of 70.8%, gram-positive at 22.6% and Candida species (spp.) at 6.6%. The most commonly isolated microorganisms were, in order of frequency, @entity4005 spp. (39.6%), @entity796 (11.3%) and Coagulase-negative staphylococci (9.4%). During the study, 12 of the 28 term babies (42.9%) and 26 of the 72 preterm babies (36.1%) died due to @entity295 , with a mortality rate of 38%. Resistance to @entity869 was 100%, to @entity3524 88%, to @entity801 73%, and to @entity4509 23% in gram-negative bacteria. No @entity2893 resistance was found except for @entity796 (25%). Resistance to @entity114 was 100% and @entity3402 58.3% in gram-positive bacteria. No glycopeptide or @entity2893 resistance was found. In conclusion, @entity295 still has a high mortality rate. Gram-negative bacteria were the most commonly isolated microorganisms with @entity4005 spp. being dominant. All gram-negative species were resistant to @entity869 , and all gram-positive bacteria were resistant to @entity114 . No glycopeptide or @entity2893 resistance was found in gram-positive bacteria. In gram-negative bacteria, low @entity4509 and high @entity801 and @entity5898 resistances were found. No @entity2893 resistance was found except for @entity796 . Restricted and alternate antibiotic usage policies seem important for the resistance problem.
