Features of @entity89 xenografted in XXXX .

@entity19 @entity89 @entity4843 @entity39
In order that the growth pattern and histologic and ultrastructural differentiation of the @entity89 be studied, tissue from three lesions was transplanted into @entity19 . Xenografts were harvested at 3 weeks, 5 weeks, 8 weeks, and 13 weeks and examined histologically and ultrastructurally. Implants could be identified as firm subcutaneous nodules, but after 3 weeks began regressing. At 13 weeks, almost total regression had occurred. Histologically, grafts were well vascularized and there was no evidence of @entity39 . Typical @entity4843 cells disappeared at an early stage. The ultrastructural features of the grafts showed giant cells lying in close association with uninuclear cells, features suggestive of a fusion process. Many cells containing microfilaments at their periphery were identified in the original lesional tissue as well as in the xenografts. These cells strongly resembled myofibroblasts. Collagen bundles were seen within the cytoplasm of stromal cells. The observations suggest that the @entity4843 cells represent a stimulus-dependent, differentiated end-stage cell population.
