The psychosocial burden of essential XXXX in an outpatient- and a community-based cohort.

@entity1 @entity308 @entity146 @entity73 @entity400
BACKGROUND AND PURPOSE: To compare psychosocial burden in @entity1 with essential @entity400 (ET) in an outpatient (OPC)- and a community-based cohort (CBC). METHODS: A sample of outpatients of a tertiary referral center (n = 180) and a community-based sample (n = 100) with ET were asked for study participation. Psychosocial aspects were assessed by a questionnaire on psychosocial aspects of ET, neuropsychological scales, quality of life, personality traits, and coping strategies. RESULTS: One hundred and seven @entity1 of the OPC and 90 individuals of the CBC participated and their results are descriptively presented. Statistical analysis was restricted to 38 pairs of OPC and CBC individuals matched for age, sex, and @entity400 severity. One-third of these individuals reported a profound impairment in everyday or professional life. Neuropsychological scales showed a severe @entity308 in 8% of the individuals and pathologic values for the general level of @entity146 symptoms in 26%. The main coping strategy was 'active problem-orientated coping'. @entity1 of the OPC perceived a more severe impact of ET on their life. Multivariate analysis revealed the Beck Depression Inventory score as the only predictive factor for the outcome variables, physical and mental component scores, of the SF-12 health survey. CONCLUSIONS: ET causes a significant @entity73 , which does depend on symptom severity but also on mood with @entity308 as the main driving factor and other so far undetermined factors.
