Remission of XXXX in type 2 @entity6 Asian population: role of tight glucose and blood pressure control.

@entity1 @entity4051 @entity6 @entity2316 @entity412 @entity165 @entity454
BACKGROUND: Asian has higher prevalence of @entity2316 ( @entity2316 ) and @entity454 when compared to Caucasian. No study to date has evaluated whether multifactorial intervention was associated with remission of microalbuminuria in type 2 @entity6 Asian population. We evaluated the effect of tightly controlling multiple factors on the remission of @entity2316 in type 2 @entity6 Chinese with microalbuminuria. MATERIALS AND METHODS: A longitudinal cohort study was collected 587 type 2 @entity6 @entity1 with microalbuminuria. Cohort members received intensified treatment to meet the following ADA recommended goals: @entity4051 c <7%, systolic blood pressure (SBP) <130mmHg, diastolic blood pressure <80   mmHg, low-density lipoprotein @entity165 <100mgdL(-1) , @entity412 <   150mgdL(-1) , high-density lipoprotein @entity165 >40mgdL(-1) for @entity1 and >50mgdL(-1) for @entity1 . Remission of microalbuminuria was defined as shift of albumin-creatinine ratio from mircoalbuminuria to normoalbuminuria. RESULTS: During the 4  5-year period, 210 (35  8%) @entity1 achieved remission to normoalbuminuria. A significant association was found between the achievement of ADA goals, including @entity4051 c <   7% [hazard ratio (HR)=1  345; 95% confidence interval (CI), 1  010-1  792; P=0  04] and SBP <130mmHg (HR, 1  516; 95% CI, 1  100-2  089; P=0  01) and remission of microalbuminuria. The intensive SBP control (<120mmHg) was significantly associated with remission of microalbuminuria (HR, 2  076; 95% CI, 1  347-3  198; P<0  001). CONCLUSIONS: The remission of @entity2316 could be achieved under multifactorial intervention. Therapeutic focus on remission by tight glycemic and blood pressure control should be considered in Asian population with @entity6 and microalbuminuria.
