Oophorectomy and XXXX . Impact on survival.

@entity1 @entity694 @entity5
Data on survival and survival free-from-recurrence were analyzed retrospectively in a group of 571 @entity1 who had undergone curative resection for @entity694 at the Mayo Clinic between 1972 and 1978. Of these @entity1 , 75 (group 1) had required bilateral oophorectomy before or at colon resection, while 496 (group 2) retained one or both ovaries. Average age, location and grade of @entity5 , and duration of follow-up were similar for both groups. Five-year-survival rate for the 571 @entity1 was 73.6%, as compared with 84.3% for matched controls. The 5-year survival rates were not significantly different for group 1 (78.0%) and group 2 (72.9%). Five-year survival free-from-recurrence also was not significantly different (82.9%, group 1 and 79.5%, group 2). @entity1 in group 1 who had grade 1 or 2 @entity5 or lesions in the sigmoid and cecum fared the best (no significant difference from controls). Incidence studies of ovarian metastases from @entity694 suggest that three to eight per cent of @entity1 should benefit from bilateral oophorectomy. This agrees with the difference in survival observed between groups 1 and 2 in this study. Our sample size is too small to statistically confirm the reliability of this difference. The design of a prospective study testing this hypothesis is outlined.
