Mineral metabolism and bone mass at peripheral and axial skeleton in XXXX .

@entity1 @entity4051 @entity6 @entity3873 @entity1674 @entity2690 @entity460 @entity3151 @entity14951
Bone mineral content (BMC), mineral homeostasis, and @entity6 control were evaluated in 31 Caucasian @entity2690 -dependent @entity6 @entity1 (disease duration 18.3 +/- 7.7 yr, mean +/- SD) with normal kidney function. To evaluate bone mass, we performed radiogrammetry and single- and dual-photon absorptiometry. In @entity1 , a significantly lower mean BMC was found in the distal radius, at a mixed trabecular-cortical (P less than .01) and a cortical (P less than .05) site, as well as in the lumbar spine (P less than .02). In @entity6 @entity1 , mean BMC was significantly reduced at the trabecularcortical (P less than .01) and cortical (P less than .05) sites of the radius but not in the lumbar spine. When expressed as densities (i.e., BMC/width or lumbar BMC/area), only the BMC/width at the radius cortical area was significantly reduced in @entity1 (P less than .05). The results of the radiogrammetry showed a larger endosteal diameter in the @entity6 @entity1 , resulting in a significantly lower cortical thickness (P less than .05). @entity6 @entity1 did not show abnormalities on radiogrammetry. @entity6 @entity1 had diminished serum @entity460 and @entity3151 concentrations (P less than .001), whereas serum parathyroid, @entity14951 , and concentrations of both total and free @entity3873 were normal. No correlation between parameters of @entity6 control ( @entity4051 , @entity2690 dose, and @entity1674 ) or @entity460 -regulating hormones and BMC were found. These data confirm that, despite large overlap of individual values, mean bone mass at the peripheral skeleton is significantly decreased in @entity6 @entity1 . Moreover, we report that the BMC of the lumbar spine is significantly reduced in female @entity6 @entity1 .
