A histological grading system for the evaluation of co-existing XXXX with @entity1963 .

@entity1 @entity154 @entity1963 @entity86 @entity528 @entity1141
The significance of @entity154 in the surgical pullthrough segment of bowel in @entity1 with @entity1963 ( @entity1963 ) has not yet been clarified. The aim of this study was to evaluate prospectively the ganglionated proximal bowel in 26 @entity1 with @entity1963 (January 1988 through January 1991). The significance of @entity154 and their influence on post operative outcome were evaluated by means of a newly devised histological scoring system based on the morphological features. Functional outcome was assessed clinically at follow-up interview. Comparison was with control specimens from 22 @entity1 undergoing unrelated bowel surgery and a further 5 @entity1 with @entity528 ( @entity528 ). Results indicated a wide spectrum of histologically identified @entity154 in @entity1 with @entity528 , the ganglionated bowel of @entity1963 and controls. Although individual abnormal features were noted in the control group, significant degrees of @entity1141 were absent. The overall degree of @entity1141 was less striking than that observed in @entity528 and in the 5 @entity1 in whom @entity528 co-existed with @entity1963 . @entity1141 of the ENS in residual bowel could be correlated with @entity86 in 4 out of 5 @entity1 (80%) with @entity1963 and features of co-existing @entity528 . In addition, milder symptoms were noted in 50% of @entity1 having a borderline score (5-6/12). This study emphasizes the relationship between clinical obstructive symptoms and a high degree of @entity1141 within the ENS. A histological grading system is of value in evaluating the spectrum of abnormal findings and prospectively identifying those with functional significance in @entity1 with @entity528 co-existing with @entity1963 .
