Prognostic parameters in radiotherapeutic management of localized XXXX .

@entity1 @entity263 @entity5
A series of 215 @entity1 with @entity263 localized to the pelvis received radical radiotherapy. Treatment results have been correlated with the @entity5 stage, @entity5 size defined independently from stage, doses of radiation and histological grade. The following ranges from 2 to 13 years (median 5 years). Local recurrence was observed in 6.6 percent of stage B, 16.1 per cent of stage C and 20 per cent of stage D1 cases. Eighty per cent of the @entity1 with stage B disease, 56 per cent with stage C and 0 per cent with stage D1 survived 5 years free of disease. Tumors less than 2 cm. in diameter were controlled uniformly, while @entity5 more than 2 cm. in diameter showed an over-all local control rate of about 85 per cent. Increasing size resulted in a higher incidence of distant metastases. A dose of 6,500 rad (180 to 200 rad per day) appears adequate for @entity5 less than 2 cm. in diameter and stage B @entity5 , while higher stage @entity5 require doses of 7,000 rad (180 to 200 rad per day). Most high grade @entity5 and massive @entity5 of any grade fail outside the pelvis.
