The role of brachytherapy in the treatment of XXXX . A report of 3 cases.

@entity1 @entity41 @entity5 @entity1161 @entity957
Advanced @entity5 has a grim prognosis: management is complicated. It may include surgery which needs to be exenterative if cure is intended, and/or @entity1161 ( @entity1161 ), the dose of which is limited by the radiosensitivity of adjacent structures. We report on 3 cases, in each of which the @entity5 was located in different anatomic sites, and we demonstrate how therapy was tailored to each situation. All 3 @entity1 had Stage III, @entity957 . They received external beam irradiation (EBI) 4000-5000 cGy to the pelvis. This is the maximal tolerable dose by most pelvic organs, but is not curative. Therefore brachytherapy was combined with EBI. In one @entity1 brachytherapy was given intraoperatively, following extensive @entity41 in the pelvis. Two @entity1 are alive and free of disease three and six and a half years later, and one @entity1 died of disease five years following therapy. For eradication of advanced @entity5 , treatment includes the combination of EBI and brachytherapy with or without debulking surgery, the role of which was not previously described in this setting. Treatment strategy should be adapted to the anatomic location of the @entity5 , its intravaginal extension and the age of the @entity1 .
