[Precocious puberty and XXXX : apropos of 13 cases].

@entity1 @entity4396 @entity3429 @entity3610 @entity251 @entity7839 @entity53 @entity1866 @entity1017 @entity26492 @entity3427
BACKGROUND: Precocious puberty and @entity3610 are two different entities which appear at different stages of ovarian development. Their association is uncommon. POPULATION: Thirteen @entity1 presented @entity26492 with sexual development before the age of 8 years; menstruations were seen at the age of 9.5 years in one @entity1 . Nine of them were given @entity7839 or @entity3429 and two @entity1 @entity4396 analog. Menarche occurred at a mean age of 11.8 +/- 1.5 years. After a mean free interval of 22 months, these thirteen @entity1 developed @entity3427 with @entity1866 (eight @entity1 ) and @entity1017 (seven @entity1 ). The diagnosis of @entity3610 was confirmed by increased plasma @entity251 (mean 91.1 +/- 14 ng/dl) and LH levels during @entity4396 test and by ultrasonography or coelioscopy. The treatment included @entity3429 plus 17 beta @entity53 ; it was discontinued in eleven cases after 2 years of treatment. Plasma @entity251 levels were normal 6 months later in association with regular menstruations. But three @entity1 presented clinical and hormonal recurrence one year later, requiring repeated treatment. CONCLUSION: This association seems to be related to the same gonadotropin dysfunction. It is necessary to regularly follow @entity1 treated for precocious puberty.
