XXXX in @entity8 .

@entity1 @entity644 @entity8 @entity459 @entity2741 @entity1347 @entity6494 @entity460 @entity1985 @entity17145
@entity8 has been classified as a @entity8 . The presence of glomerular pathologic findings attributable to @entity2741 has been observed in only a few @entity1 and therefore has been considered an unusual finding. In the current study, @entity460 deposition within glomeruli was investigated in 2 @entity1 with extreme elevations in serum @entity460 levels and @entity8 . The study material consisted of a renal biopsy specimen from a 31-year-old @entity1 ( @entity1 1) who had @entity6494 and a serum @entity460 level of 20.2 mg/dL (5.0 mmol/L) and autopsy kidney specimens from a 19-year-old @entity1 ( @entity1 2) who was being evaluated for @entity459 and a @entity460 level of 18.4 mg/dL (4.6 mmol/L). The renal biopsy specimen for @entity1 1 exhibited @entity460 deposits present in the glomerular capillary basement membranes, where they were associated with @entity1347 (21% of glomeruli). Nine percent of the cortical tubules contained calcifications. In @entity1 2, @entity460 was found in the mesangial areas in 95% of glomeruli, filling the Bowman space in 7% of glomeruli, or associated with capillary basement membranes and @entity1347 (12% of glomeruli). Fifteen percent of cortical tubules, 4% of outer medullary tubules, and 40% of inner medullary tubules were calcified. In neither case was there immunofluorescence or electron microscopic evidence of primary @entity8 . Thus, glomerular calcification may exceed that occurring in the cortical and outer medullary tubules and may play a significant role in the loss of renal function in @entity8 . @entity8 may also be recognized as an additional cause of @entity17145 and @entity1985 range @entity644 in @entity1 with extremely high levels of serum @entity460 .
