Postoperative Outcomes of Enucleation and Standard Resections in XXXX with a @entity788 .

@entity1 @entity788 @entity5 @entity260 @entity3210 @entity3
BACKGROUND: Either enucleation or more extended resection is performed to treat @entity1 with @entity788 ( @entity788 ). Aim was to analyze the postoperative complications for each operation separately. Furthermore, independent risk factors for complications and incidence of @entity3210 were analyzed. METHODS: Retrospective all resected @entity1 from two academic hospitals in The Netherlands between 1992 and 2013 were included. @entity260 were scored by both ISGPS and Clavien-Dindo criteria. Based on @entity5 location, operations were compared. Independent risk factors for overall complications were identified. During long-term follow-up, @entity3210 and recurrent disease were analyzed. RESULTS: @entity5 enucleation was performed in 60/205 @entity1 (29  %), pancreatoduodenectomy in 65/205 (31  %), distal pancreatectomy in 72/205 (35  %) and central pancreatectomy in 8/205 (4  %) @entity1 . Overall complications after @entity5 enucleation of the pancreatic head and pancreatoduodenectomy were comparable, 24/35 (69  %) versus 52/65 (80  %). The same was found after @entity5 enucleation and resection of the pancreatic tail (36 vs.58  %). Number of re-interventions and readmissions were comparable between all operations. After pancreatoduodenectomy, 33/65 @entity1 had lymph node @entity3 and in @entity1 with @entity5 size  <=2  cm, 55  % had lymph node @entity3 . @entity5 in the head and BMI >= 25  kg/m(2) were independent risk factors for complications after enucleation. During follow-up, incidence of exocrine and endocrine insufficiency was significant higher after pancreatoduodenectomy (resp. 55 and 19  %) compared to the @entity5 enucleation and distal pancreatectomy(resp. 5 and 7  % vs.8 and 13  %). After @entity5 enucleation 19  % developed recurrent disease. CONCLUSION: Since the complication rate, need for re-interventions and readmissions were comparable for all resections, @entity5 enucleation may be regarded as high risk. Appropriate operation should be based on @entity5 size, location, and functional status of the @entity788 .
