Expression of inducible XXXX synthase in antrochoanal @entity1127 .

@entity32 @entity1127 @entity4 @entity17220 @entity842 @entity56 @entity3623 @entity480
OBJECTIVE: @entity1127 ( @entity1127 ) is a polypoid lesion originating from the maxillary sinus, emerging from the ostium and extending to the choana. Although the etiologic causes of @entity1127 are not known completely, it presents a fairly uniform clinical appearance. @entity842 (NO) has an important role in non-specific immunoreactions and @entity32 in various tissues and has a main regulatory role in airway function and seems to involve in pathomechanism of several @entity17220 . NO is synthesized by the effect of three isoforms of @entity842 synthase i.e. @entity3623 ( @entity3623 ). Some studies revealed that @entity1127 has some different characteristics from the ordinary @entity480 . In the present study, in order to compare @entity1127 with @entity56 (NANP), we detected and localized the @entity3623 expression and also evaluate some histological parameters. METHODS: Twenty-six cases were chosen from the files and four controls were used. The cases were separated as follows: normal inferior turbinate mucosa as control (n=4) ACPs (n=8), @entity480 ( @entity480 ) (n=9), and NANP (n=9). Five-micrometer thick sections were prepared from the paraffin sections of @entity1127 and normal nasal mucosa to quantify the @entity3623 expression. @entity3623 protein was observed in the cytoplasm of epithelial and stromal inflammatory cells. @entity3623 protein expression in the groups was assessed according to the intensity of staining and histomorphological parameters, @entity4 , lymphocytic and eosinophilic cell infiltration were detected semi quantitatively. RESULTS: @entity3623 expressions, either stromal or epithelial, were not different from each other among the four groups. Although it is not statistically significant, we noted that @entity480 and @entity1127 frequently showed moderate and severe @entity3623 protein expression in epithelial and stromal parts when compared with NANPs and controls. Also, @entity3623 expression was significantly higher in the stroma of the ANPs than NANPs (P=0.012). CONCLUSIONS: ACPs and ANPs have frequently showed moderate and significant epithelial and stromal @entity3623 expression. Further studies are needed in large groups to elucidate differences between @entity1127 and the other @entity480 .
