First documented cases of systemic lupus erythematosus in XXXX .

@entity1 @entity1665 @entity625 @entity1910 @entity500 @entity229 @entity786 @entity6383 @entity177 @entity11534 @entity74 @entity3456 @entity2408
OBJECTIVE: We describe in this first series of lupus documented in @entity3456 , the epidemiological, diagnostic, therapeutic and prognostic aspects. METHOD: This is a prospective study in internal medicine at the National Hospital of Niamey during 10 years. ACR criteria were used as diagnostic criteria. RESULTS: We identified only 9 cases with a frequency of 0.05 % (7 @entity1 , 2 @entity1 ) with a mean age of 36.7 years [range, (26, 48)]. Frequent manifestations were prolonged fever (8 cases), @entity1910 (6 cases), @entity625 (6 cases), @entity1665 (5 cases), discoid lupus (3 cases), @entity74 (7 cases), @entity11534 (4 cases) and @entity177 (4 cases). All @entity1 had at least 4 ACR criteria with an average of 6.11 criteria. ANA were positive in 8 @entity1 with an average of 1/568, 68 [extremes (1/1280-1/160)]. The most commonly molecules used were @entity229 , @entity500 and @entity6383 . The Mycof  nolate Mof  til, @entity786 and @entity2408 were used in a single @entity1 . The outcome was favorable in 8 @entity1 and we deplore the death of one @entity1 . CONCLUSION: Under diagnosis would be the basis of the low prevalence of lupus in @entity3456 . Diagnostic means are necessary for epidemiological studies in order to have more representative data.
