Comparison of needle biopsy with cytologic analysis for the evaluation of XXXX : analysis of 414 cases.

@entity1 @entity1143 @entity6113 @entity706 @entity5 @entity1669 @entity5641 @entity3620 @entity3483 @entity3254
We retrospectively studied the results from thoracenteses and needle biopsies of the pleura performed in 414 @entity1 with @entity1143 between 1973 and 1982. The final causes of effusion were @entity5 in 281 @entity1 (67.9%) and nonmalignant disease in 133 (32.1%). The presence of @entity5 was established by cytologic study in 162 @entity1 (57.6%), by needle biopsy in 123 (43%), and by either cytologic analysis or biopsy in 182 (64.7%). In only 7.1% of the 281 @entity1 with @entity3483 did biopsy reveal @entity5 when the results of cytologic study were negative for @entity5 . Nearly half of the @entity1 with @entity706 had @entity6113 of the pleural fluid, but neither this finding nor the lymphocytic @entity5641 noted on biopsy was diagnostic of @entity1669 . Among the @entity1 with @entity3620 , thoracotomy was necessary to confirm the diagnosis in 60.9%. In the @entity1 with nonmalignant diseases, with the exception of six with @entity3254 , pleural biopsy was nondiagnostic even though the causes of @entity1143 were apparent from the clinical features. The causes of @entity1143 remained unknown in 82 @entity1 (19.8%). Pleural biopsy failed to provide adequate tissue in 55 @entity1 (13.3%). This study shows that cytologic analysis has a higher sensitivity (P less than 0.001) than needle biopsy for diagnosing @entity3483 . The value of needle biopsy is limited in establishing the cause of @entity1143 that results from either malignant or nonmalignant disease, with the exception of @entity3254 .(ABSTRACT TRUNCATED AT 250 WORDS)
