Biliary stenting in XXXX : an analysis of predictive factors for survival.

@entity1 @entity3883 @entity788 @entity5 @entity1109 @entity797 @entity1442 @entity201 @entity253
PURPOSE: Stenting of the biliary tree is a common palliative procedure to relieve @entity3883 in @entity1442 . Although effective in relief of @entity253 and @entity1109 , little information is available on predictive factors for survival post-procedure. This retrospective study sought to assess factors influencing post-procedure survival in @entity5 @entity1 after biliary stenting. METHODS: Case notes of all @entity1 from a regional academic @entity5 center, who underwent biliary stenting for @entity3883 related to @entity5 during 2008 and 2009 were reviewed. We collected epidemiological, biochemical, treatment and survival data on all @entity1 . We used Kaplan-Meyer analysis to assess survival from day of first biliary stenting (adjusted for @entity5 types), and the @entity797 proportional hazards model for univariate and multivariate analysis. RESULTS: One hundred and ninety-four @entity1 were included in the final analysis. Most cases were related to @entity788 or @entity201 (89 and 46 cases respectively). Median survival for all @entity1 was 143 days. In multivariate analysis serum albumin >= 34 g/L at the time of procedure (hazard ratio 0.573; 95% confidence interval 0.424-0.773, P<0.001) and chemotherapy post-stent (hazard ratio 0.636; 95% confidence interval 0.455-0.889, P=0.008) were two independent prognostic factors predicting a better survival post-stenting. The 30 day mortality post-procedure in the 194 @entity1 was 12%. CONCLUSION: This study suggests that stenting of the biliary tree in cases of @entity5 allows durable @entity1109 even in cases where further active chemotherapy treatment is not possible. However, the better outcome observed in @entity1 with albumin >= 34 g/L and those receiving chemotherapy post-stent requires further validation.
