[ XXXX in Sch  nlein-Henoch purpura: a retrospective study of the last 25 years].

@entity1 @entity644 @entity8 @entity1333 @entity56 @entity811 @entity454
Sch  nlein-Henoch purpura is a systemic @entity1333 due to IgA-mediated @entity56 , almost exclusively affecting the pediatric age group. Long-term prognosis is mainly conditioned by renal involvement, which can appear at onset or during the course of the disease. To evaluate renal involvement, 764 @entity1 with Sch  nlein-Henoch purpura were retrospectively reviewed. Of these, 153 (20 %) had renal involvement, the most frequent form of presentation being non-nephrotic @entity811 / @entity644 (67 @entity1 ) followed by isolated @entity811 (41 @entity1 ). Renal biopsy was performed in 39 @entity1 , and the most frequent pathological findings were diffuse mesangial proliferation with IgA deposits and less than 50 % of crescentic glomeruli. Treatment was not curative. Three @entity1 (2 %) progressed to @entity454 and required renal transplantation. One @entity1 died. Notably, two of the @entity1 who underwent renal transplantation had disease recurrence. We stress that @entity8 is usually benign and that it requires long-term follow-up.
