Marked Direct XXXX due to @entity2756 in an Adult with @entity3458 .

@entity1 @entity2756 @entity648 @entity3458 @entity4580 @entity5553 @entity1448 @entity253 @entity99 @entity3638
Drugs are a significant cause of @entity99 . @entity99 ( @entity99 ) can cause acute @entity99 , @entity1448 , or a mixed pattern. @entity2756 is a commonly used antibiotic and has been associated with reversible @entity253 , pseudolithiasis, and @entity1448 . A 32-year-old male with @entity3458 was admitted to the hospital for acute sickle cell crisis. On the second day of hospitalization, he developed cough and rhonchi with chest X-ray revealing right middle lobe infiltrates. @entity2756 and @entity4580 were initiated. Subsequently, he developed conjugated @entity3638 and mild transaminitis. His total @entity648 trended upwards from 3.3   mg/dL on admission to 17   mg/dL. It was predominantly conjugated @entity648 , with preadmission @entity648 levels of 3-4   mg/dL. His transaminases were mildly elevated as well compared to previous levels. Extensive workup for @entity648 elevation was unremarkable. @entity2756 was switched to @entity5553 and the @entity3638 improved. On ambulatory follow-up, his @entity648 remained below 4   mg/dL. @entity2756 may be associated with marked direct @entity3638 particularly in sickle cell @entity1 with chronic liver chemistry abnormalities. In the case of elevated @entity648 with concomitant @entity2756 use, elimination of the offending agent should be considered.
