XXXX : Brain Magnetic Resonance Imaging and  Neuropathology Findings.

@entity1 @entity154 @entity410 @entity3932 @entity8568 @entity6795 @entity302 @entity35457 @entity386
BACKGROUND: We describe the brain magnetic resonance imaging (MRI) abnormalities and neuropathologic findings in @entity1 with @entity3932 and medically @entity302 . METHODS: We retrospectively reviewed the clinical features, preoperative MRI studies, and pathologic findings of all @entity1 with @entity3932 who underwent excisional surgery for intractable @entity302 at Boston @entity1 's Hospital between 1993 and  2011. RESULTS: Eleven @entity1 (male/female  =  4/7) with @entity3932 were identified who underwent surgery for intractable @entity302 (mean age 13    6.2  months), including hemispherectomy (n  =  10) and focal cortical resection (n  =  1). Mean age at @entity410 onset was 15    11  weeks. Fifty-five percent (n  =  6) of @entity1 exhibited two different types of @entity410 , and 18% (n  =  2) had three types of @entity410 . @entity35457 were the most common type, occurring in nine @entity1 ; @entity386 was the second most common, occurring in four @entity1 . Brain MRIs were reviewed in five @entity1 . Histopathologic examination revealed signs of varied degrees of @entity154 in seven of 11 @entity1 . Overall, there were no abnormalities in the MRIs that corresponded directly with the pathologic findings except in one @entity1 with @entity8568 . CONCLUSIONS: In spite of pathologic findings of @entity154 in varied degrees, these findings could not be readily detected on brain MRIs. The failure to detect focal @entity6795 on MRIs may be attributable to the subtle microscopic nature of the abnormalities; in some of the older individuals, the imaging studies available for review were done during an advanced stage of the disease.
