Gastric secretion, gastroduodenal histological changes, and serum @entity8243 in chronic XXXX .

@entity1 @entity167 @entity1066 @entity1689 @entity8883 @entity8243 @entity2210 @entity1575 @entity356 @entity9317
Controversial data have been reported on gastric acid secretion in @entity1 with @entity1689 . Moreover, studies on gastroduodenal morphological changes in @entity1 with this disease and with other @entity167 -related conditions have given different results. Basal and penta- @entity8243 -stimulated gastric secretion, histological changes of @entity356 , and basal and meal-stimulated @entity8243 were measured in 21 @entity1 with chronic @entity8883 and in the following pair-matched groups: 21 chronic alcoholics and 21 control subjects ( @entity2210 ), and in 19 @entity1 with proven @entity1575 of alcoholic origin. No @entity1 suffered from peptic @entity1066 . Moreover, gastric secretion was also measured in 51 @entity1 with proven duodenal @entity1066 and in 34 healthy subjects. Basal acid output in @entity1 with @entity1689 was significantly higher (p less than 0.05) than in the other groups, except for the @entity1 with duodenal @entity1066 . Peak acid output values in @entity1 with @entity1689 were similar to those measured in @entity1 with duodenal @entity1066 , and they were higher than in the healthy subject group and in @entity1 with @entity1575 , but statistical significance was not attained for @entity1 with @entity2210 . An increased frequency of @entity9317 was found in @entity1 with @entity1689 , whereas an increased frequency of @entity356 in the duodenal bulb was observed in all the @entity1 with @entity167 -related conditions considered. No relevant differences among the considered groups were found relating to gastric histological changes. Basal and meal-stimulated @entity8243 were similar in all the studied groups. This study suggests that in @entity1 with @entity1689 there is increased gastric secretion and probably an increased capacity for secretion of acid. Moreover, in @entity1 with @entity1689 , @entity9317 seems to be frequent, but it probably is not directly related to chronic @entity167 consumption.
