Effects of Oral Contraceptive Use on Anterior Cruciate XXXX Epidemiology.

@entity172 @entity1 @entity7280 @entity130
INTRODUCTION/PURPOSE: Anterior cruciate @entity130 often incur major consequences for athletes. Elevated @entity172 levels are likely increase the risk for injury. This risk may be partially or fully mitigated by the use of @entity7280 . The purpose of this study was to determine if @entity1 undergoing anterior cruciate ligament surgical reconstruction were less likely to use @entity7280 than matched noninjured population. METHODS: This is a case-control study utilizing national insurance claims data from 2002 TO 2012. @entity1 included @entity1 age 15-39 yr. Cases were defined as those receiving surgical reconstruction of the anterior cruciate ligament between 2002 and 2012. Controls were matched 3/1 to cases. Exposure to @entity7280 was defined as the presence of any prescription fill for @entity7280 during the previous 12 months to index date. Conditional multivariate logistic regression was used to estimate adjusted odds ratios for the use of @entity7280 . RESULTS: @entity1 age 15-19 yr undergoing surgical repair of the anterior cruciate ligament were 18% less likely to use @entity7280 than matched controls (adjusted odds ratio, 0.82; 95% CI, 0.75-0.91; P < 0.0001). Cases among two older age groups, 25-29 and 30-34 yr, were more likely to use @entity7280 than controls with adjusted odds ratios of 1.15 (95% CI, 1.02-1.30; P < 0.05) and 1.16 (95% CI, 1.04-1.31; P < 0.05), respectively. CONCLUSIONS: The use of @entity7280 potentially modifies anterior cruciate @entity130 risk in young @entity1 . Despite reports that athletes, who are more prone to anterior cruciate @entity130 , use @entity7280 at about twice the rate of nonathletes, these data suggest that @entity1 ages 15-19 yr undergoing anterior cruciate ligament reconstruction used @entity7280 at a lower rate than the general population.
