Placebo use in XXXX management: a mechanism-based educational intervention enhances placebo treatment acceptability.

@entity1 @entity4512 @entity1118 @entity158
UNASSIGNED: Healthcare providers use treatments whose effectiveness's derive partially or completely from 'non-specific' factors, frequently referred to as placebo effects. While the ethics of interventional placebo use continues to be debated, evidence suggests that placebos can produce clinically meaningful analgesic effects. Burgeoning evidence suggest that @entity1 with @entity1118 may be open to placebos treatments under certain contexts despite limited knowledge of their well-established psycho-neurobiological underpinnings. This investigation sought to examine the effects of a brief, mechanism-based placebo analgesia educational intervention on aspects placebo knowledge and acceptability. @entity1 with chronic @entity4512 completed a web-based survey where they rated their knowledge of placebo analgesia; assessed placebo acceptability across different medical contexts; and evaluated six unique @entity1 -provider treatment scenarios to assess the role of treatment effectiveness and deception on @entity1 /provider attributions. Using a pre-post design, @entity1 were randomized to receive either a placebo educational intervention or an active control education. Results demonstrated that the educational intervention greatly improved perceptions of placebo knowledge, effectiveness, and acceptability, even in deceptive treatment contexts. This is the first study of its kind to demonstrate the value of an educational intervention in increasing openness to and knowledge of placebo analgesic interventions among @entity1 with chronic @entity4512 . PERSPECTIVE: This article highlights how @entity1 with @entity1118 may be open to placebo interventions, particularly adjunct/complementary treatments, when provided education on the neurobiological and psychological mechanisms underlying placebo effects. Study findings highlight ethically acceptable ways to potentially utilize placebo factors to enhance existing @entity158 treatments and improve @entity1 health outcomes.
