Performance characteristics of the simplified version of XXXX activity score (SASDAS).

@entity1 @entity1691 @entity1851
UNASSIGNED: Various types of disease activity measures are available for @entity1691 ( @entity1691 ), and there is no gold standard for all individual @entity1 . The @entity1691 activity score (ASDAS) is highly discriminatory, sensitive to change, and associated with structural progression. A simplified version of the ASDAS (SASDAS) was proposed and found to be a simple and practical tool to assess disease activity. Our aim was to test the performance characteristics of the SASDAS and compare it with validated tools. In total, 97 consecutive @entity1691 ( @entity1691 ) @entity1 were included in the study. Disease activity was assessed by the ASDAS-erythrocyte sedimentation rate (ESR), @entity1851 ( @entity1851 ), bath @entity1691 activity index (BASDAI), and SASDAS. The relationship among these activity indices and the level of agreement of various activity categories were tested. There was a strong correlation between the SASDAS and other activity indices, including the BASDAI (r   =   0.916, p   <   0.001), @entity1851 (r   =   0.847, p   <   0.001), and ASDAS-ESR (r   =   0.942, p   <   0.001). Although the agreement between the ASDAS-ESR and SASDAS was good (weighted kappa of 0.744 and total agreement of 77  %), there was moderate agreement between the ASDAS- @entity1851 and SASDAS (weighted kappa of 0.579 and total agreement of 66  %). The disagreement was particularly striking in "moderate" and "high disease activity" states. Approximately 40  % of @entity1 classified as moderate activity according to the ASDAS-ESR and 45  % according to the @entity1851 were differentially categorized by the SASDAS. The results of the present analysis suggest that the simplified version of the ASDAS-ESR should be further validated in various settings and populations due to a questionable level of agreement between the @entity1851 and SASDAS.
