Long-term outcome after early repair of iatrogenic XXXX . A national Danish multicentre study.

@entity1 @entity1157 @entity1317 @entity850
BACKGROUND: The aim of this retrospective study was to evaluate the peri-operative and long-term outcome after early repair with a hepaticojejunostomy (HJ). METHODS: Between 1995 and 2010, a nationwide, retrospective multi-centre study was conducted. All iatrogenic @entity1157 ( @entity1157 ) sustained during a cholecystectomy and repaired with HJ in the five Hepato-Pancreatico-Biliary centres in Denmark were included. RESULTS: In total, 139 @entity1 had an HJ repair. The median time from the @entity1157 to reconstruction was 5 days. A concomitant @entity1317 was identified in 26 cases (19%). Post-operative morbidity was 36% and mortality was 4%. Forty-two @entity1 (30%) had a @entity850 of the HJ. The median follow-up time without @entity850 was 102 months. Nineteen out of the 42 @entity1 with post-reconstruction biliary strictures had a re-HJ. Twenty-three @entity1 were managed with percutaneous transhepatic cholangiography and dilation. The overall success rate of re-establishing the biliodigestive flow approached 93%. No association was found between timing of repair, concomitant @entity1317 , level of injury and @entity850 formation. CONCLUSION: In this national, unselected and consecutive cohort of @entity1 with @entity1157 repaired by early HJ we found a considerable risk of long-term complications (e.g. 30% @entity850 rate) and mortality in both the short- and the long-term perspective.
