Behavioral and subjective effects of @entity835 following partial XXXX .

@entity835 @entity839 @entity1949 @entity25
This study tested whether performance would be more impaired when @entity835 use followed partial @entity1949 (PSD) than when @entity835 use followed a typical night of sleep. Seven recreational @entity835 users (mean 15 of last 30 days) completed six test sessions in a double-blind randomized within-subject design. Each session began with an overnight stay in a sleep laboratory. Bed and wake times were calculated from mean data on individual sleep diaries. Time-in-bed was either regular (mean=8.2 h) or shortened (first 65% of regular time-in-bed deprived). At 3 and 5 h after waking, daytime @entity25 was measured with self-report questionnaires and a sleep latency test. Approximately 6.5 h after waking, subjects smoked a @entity835 cigarette (0.003, 2, or 3.5% delta-9 @entity839 [ @entity839 ]). Test batteries were completed 2, 62, and 122 min after smoking ended. Sleepiness was significantly greater following PSD than after regular sleep. Following regular sleep, heart rate increases with active @entity839 doses were comparable, but heart rate with 2% @entity839 was significantly less elevated following PSD. Ratings of "impaired" and "stoned" increased with both @entity839 doses after regular sleep and were further increased with 3.5% @entity839 after PSD. High-potency @entity835 increased body sway similarly across sleep conditions. There were no significant effects of @entity835 or PSD, alone or in combination, on brake latency. Thus, while PSD increased the dose-dependence of @entity839 effects on heart rate and subjective impairment, it did not enhance the effects of @entity835 on standing balance and brake latency.
