Relation between increased anaerobic glycolysis and visual acuity in long-standing XXXX without @entity989 .

@entity1 @entity6 @entity63 @entity519 @entity880 @entity989 @entity413 @entity855
In @entity6 , blood flow to essential organs including the retina is reduced owing to macrovascular and/or microvascular changes. Poor glycolytic pathway of @entity413 metabolism owing to tissue @entity519 caused by @entity63 at capillary bed of essential organs produces excessive @entity880 and less of @entity855 , which lead to poor cellular function. The purpose of the study was to evaluate the relationship between increased anaerobic glycolysis and visual acuity in @entity6 without @entity989 . Fifty @entity1 of @entity6 of 10-12 years duration, without @entity989 , constituted the study group. The controls were 50 age-matched healthy @entity1 without @entity6 . Blood @entity880 level and best-corrected visual acuity (BCVA) were measured in both the groups. The mean blood @entity880 level was 1.05 mM/l in the control group and 2.32 mM/l in the study group. BCVA of 20/20 (log MAR 0) was seen in 48 (96%) @entity1 of the control group and in 27 (54%) @entity1 of the study group. BCVA of 20/30 (log MAR 0.2) was seen in 23 (46%) @entity1 in the study group and 2 (4%) in the control group. Association of higher blood @entity880 level with decreased BCVA in the study group was statistically significant (P< 0.001).
