Morphological characteristics of lateral pelvic lymph nodes in XXXX .

@entity1 @entity851 @entity189 @entity3
AIM: Macroscopic and imaging indicators for lymph node @entity3 have been documented not in lateral pelvic lymph nodes but in mesorectal lymph nodes in @entity1 with @entity189 . We conducted this study to uncover morphological characteristics of lateral pelvic lymph nodes in @entity1 with @entity189 . MATERIALS AND METHODS: Fifty-eight @entity1 with locally advanced @entity189 who had total mesorectal excision and lateral pelvic lymph node dissection were studied. Total number of lateral pelvic lymph nodes evaluated was 462, with 538 mesorectal lymph nodes being used for comparison. Factors of lymph nodes evaluated were size (long- and short-axes diameters), shape (ovoid and irregular), and heterogeneity of internal structure. Receiver operating characteristic (ROC) curve analysis was used to compare the diagnostic accuracy of each factor. RESULTS: Lateral pelvic lymph node at non-metastatic status appeared to be longer (4.5 vs 3.5 mm) and thinner (2.2 vs 2.6 mm) than mesorectal lymph nodes. ROC curve analysis, for discriminating non-metastatic and metastatic lateral pelvic lymph nodes, revealed that a @entity851 diameter appeared to be the most prominent factor with highest area under curve (0.907) and was more reliable than either long-axis diameter (0.811) or shape (0.527) other than internal structure (1.00). A @entity851 diameter was an independent risk factor for @entity3 by multivariate analysis with an odds ratio of 1.29 (p < 0.0001, 95% confident interval, 1.22-1.36). The most reliable cut-off value was 4 mm with 96% of sensitivity, 68% of specificity, and 82% of overall accuracy. CONCLUSION: Lateral pelvic lymph nodes tended to be longer and thinner than mesorectal lymph nodes at non-metastatic status. A @entity851 diameter of 4 mm or larger was the prominent indicator of @entity3 in lateral pelvic lymph nodes.
