Spectral-domain optical coherence tomographic features of XXXX membranes in multifocal @entity3193 and punctate inner choroidopathy.

@entity1 @entity1940 @entity3012 @entity3193 @entity6519 @entity941
PURPOSE: To describe the spectral-domain optical coherence tomographic (SD-OCT) features of inflammatory @entity1940 membranes (iCNV) in multifocal @entity3193 and punctate inner choroidopathy, and to compare them to those of the acute inflammatory lesions in the same underlying diseases. This is a retrospective, consecutive, observational case series. METHODS: Each @entity1 underwent a comprehensive eye examination, fundus photography, and @entity941 angiography (FA) on the initial visit. SD-OCT features of iCNV were reviewed at presentation and 4  weeks later, and were compared to SD-OCT features of the inflammatory lesions. There were ten eyes with iCNV and eight eyes with the acute lesions of @entity6519 . RESULTS: All iCNV had a sub-retinal pigment epithelium (sub-RPE) component and a subretinal or retinal component that infiltrated the outer retinal layers to different extents. All iCNV had associated fluid exudation, and all showed RPE and inner segment/outer segment junction layer (IS/ @entity3012 ) disruption. On the other hand, approximately half of the inflammatory lesions were confined between Bruch's membrane and RPE; the rest showed infiltration into the outer retinal layers in a pattern similar to iCNV, with no fluid exudation but with associated @entity3193 . In most of them, disruption of RPE and IS/ @entity3012 was also noted. CONCLUSIONS: The acute lesions of @entity6519 can be difficult to distinguish from iCNV based on clinical examination and FA. However, iCNV demonstrate characteristic SD-OCT features not seen with the inflammatory lesions. These findings may help to differentiate these two entities that typically require different treatments.
