[Specific desensitization with allergen extracts absorbed on XXXX (Pasteur Institute). Clinical and biological study apropos of 107 cases].

@entity1 @entity3617 @entity2023 @entity565 @entity78 @entity2490 @entity25878 @entity56
107 @entity56 @entity1 (71 @entity1 and 36 adults) were desensitized with allergen extracts adsorbed on @entity78 . @entity1 were selected following their symptoms ( @entity565 , @entity2490 , @entity3617 , @entity2023 ), skin tests ( @entity25878 or Prick) and total or specific IgE levels (PRIST and RAST). A mean of 17 month treatment, usually with house dust and mite extracts, rarely with house dust extract alone and in 6 cases with a mixture of grass and cereal pollens. The major aim of this study was to test the immunotherapy efficiency and to compare the IgE level variations and the clinical results. The treatment was found very good in 62% of the cases, good in 28%, and negative in 10% of the cases. The mean total IgE level has decreased of 58%, and the specific IgE level has decreased in 77% of the @entity1 . The number of @entity1 with a RAST class O to house dust and mites has increased respectively of 23% and 24.4% after the treatment. Besides some very good cases where the IgE levels have dropped there are lew relations between the total or specific IgE antibodies and the clinical results. The tolerance of the hyposensitization treatment was judged excellent. In conclusion, the @entity78 absorbed allergen extracts are confirmed as efficient and safe in immunotherapy.
