Does daily tobacco smoking affect outcomes after microdecompression for degenerative central XXXX ? - A multicenter observational registry-based study.

@entity1 @entity2649 @entity260
BACKGROUND: There are limited scientific data on the impact of smoking on @entity1 -reported outcomes following minimally invasive spine surgery. The aim of this multicenter observational study was to examine the relationship between daily smoking and @entity1 -reported outcome at 1 year using the Oswestry Disability Index (ODI) after microdecompression for single- and two-level central @entity2649 ( @entity2649 ). Secondary outcomes were the length of hospital stays, perioperative and @entity260 . METHOD: Data were collected through the Norwegian Registry for Spine Surgery (NORspine). RESULTS: A total of 825 @entity1 were included (619 nonsmokers and 206 smokers). For the whole @entity1 population there was a significant difference between preoperative ODI and ODI at 1 year (17.3 points, 95% CI 15.93-18.67, p   <   0.001). There was a significant difference in ODI change at 1 year between nonsmokers and smokers (4.2 points, 95% CI 0.98-7.34, p   =   0.010). At 1 year 69.6% of nonsmokers had achieved a minimal clinically important difference (>= 10 points ODI improvement) compared to 60.8% of smokers (p   =   0.008). There was no difference between nonsmokers and smokers in the overall complication rate (11.6% vs. 9.2%, p   =   0.34). There was no difference between nonsmokers and smokers in length of hospital stays for either single-level (2.3 vs. 2.2 days, p   =   0.99) or two-level (3.1 vs. 2.3 days, p   =   0.175) microdecompression. Smoking was identified as a negative predictor for ODI change in a multiple regression analysis (p   =   0.001) CONCLUSIONS: Nonsmokers experienced a significantly larger improvement at 1 year following microdecompression for @entity2649 compared to smokers. Smokers were less likely to achieve a minimal clinically important difference. However, it should be emphasized that considerable improvement also was found among smokers.
