[Usefulness of amylase isoenzyme determination for the diagnosis of XXXX ].

@entity1 @entity788 @entity6 @entity5 @entity660 @entity2 @entity420 @entity12828
Serum amylase shows the greatest increase among the various pancreatic enzymes that increase at the onset of acute @entity788 . However, the diagnostic value of the total serum amylase activity has been questioned due to its lack of specificity. To differentiate @entity12828 due to @entity660 from that due to other causes, the activity of pancreatic amylase should be determined by using a monoclonal antibody that specifically binds to pancreatic or salivary amylase, or by electrophoresis. The most useful and accurate method for distinguishing pancreatic from salivary-type @entity12828 is isoamylase analysis by electrophoresis. In @entity1 with acute @entity788 , increase of Amylase-1 and -2 is accompanied by the appearance of Amylase-4, a minor component of the pancreatic-type isoamylases, and by disappearance of the salivary-type isoenzymes, thereby leaving a pattern of the pancreatic isoenzymes alone. This @entity788 pattern persists for about 10 days after the onset of illness. Therefore, if such a pattern is found in a @entity1 with clinical findings suggesting acute @entity788 despite a normal serum amylase level, the @entity1 can be diagnosed as having acute @entity788 or a recent attack of the disease. However, the existence of an inherited trait of the @entity788 pattern in some healthy individuals must be borne in mind. @entity1 with recurrent chronic @entity788 also show @entity788 , whereas the pancreatic amylase activity decreases when pancreatic exocrine insufficiency progresses. @entity12828 due to elevated salivary amylase activity is also common in @entity1 with @entity6 or @entity5 such as @entity2 ( @entity420 ). @entity12828 is also found following various types of operation. In most cases, it is salivary-type @entity12828 .(ABSTRACT TRUNCATED AT 250 WORDS)
