Static and dynamic prognostic factors for XXXX .

@entity1 @entity75 @entity879 @entity843 @entity3851
BACKGROUND/AIMS: Hepatitis-B-related @entity879 has a poor prognosis. However, the advent of potent oral antiviral agents means that some @entity1 can now recover with medical treatment. We aimed to identify the prognostic factors for @entity879 including the initial as well as the dynamically changing clinical parameters during admission. METHODS: Sixty-seven @entity1 were retrospectively enrolled from 2003 to 2012 at Samsung Medical Center. The @entity1 were classified into three categories: Recovery group (n=23), Liver transplantation group (n=28), and Death group (n=16). The Liver transplantation and Death groups were combined into an Unfavorable prognosis group. We analyzed the prognostic factors including the @entity3851 ( @entity3851 ) scores determined at 3-day intervals. RESULTS: A multivariable analysis showed that the unfavorable prognostic factors were a high initial @entity3851 score (>= 28) (odds ratio [OR] =6.64, p=0.015), moderate-to-severe @entity843 at admission (OR=6.71, P=0.012), and the aggravation of hepatic @entity75 during hospitalization (>= grade III) (OR=15.41, P=0.013). Compared with the baseline level, significant reductions in the @entity3851 scores were observed on the 7th day after admission in the Recovery group (P=0.016). CONCLUSIONS: Dynamic changes in clinical parameters during admission are useful prognostic factors for @entity879 .
