XXXX -centred outcomes comparing transmucosal implant placement with an open approach in the maxilla: a prospective, non-randomized pilot study.

@entity1 @entity4 @entity158 @entity1062
It was the aim of the study to assess differences in @entity1 morbidity between transmucosal implant placement and implant installation after elevation of mucoperiosteal flaps. In five of the @entity1 , implants were placed in the maxilla transmucosally using a CAD/CAM surgical template [ @entity1062 ( @entity1062 )]. In the remaining five @entity1 , the implants were installed after the elevation of mucoperiosteal flaps [control group (CG)]. Directly after surgery, at days 1 and 7 after surgery the @entity1 rated @entity158 and discomfort on a visual analogue scale (0=minimal @entity158 and discomfort, 100=maximal @entity158 and discomfort). Optical three-dimensional images were assessed preoperatively and at days 1 and 7 after surgery to determine the visible soft tissue swelling of the upper lip and cheeks. Directly postoperatively, the mean pairwise difference between both groups in view of @entity158 and discomfort ratings (control minus test) was 45.6 (SD, 20.7). At days 1 and 7, the mean differences were 51.6 (SD, 21.8) and 19 (SD, 8), respectively. The overall test of the area under curve (AUC) against the null hypothesis 'AUC of pairwise differences of @entity158 score over study time equals null' yielded a significant difference (P=0.01). The mean pairwise difference between both groups in view of soft tissue volume increase was 6.1 (SD, 2) cm(3) at day 1 after surgery and 4.6 (SD, 1.2) cm(3) at day 7. The overall test of the AUC against the null hypothesis 'AUC of pairwise differences of @entity4 measurements over study time equals null' yielded a significant difference (P=0.002). Within the limitations of this pilot study, it could be shown that transmucosal implant placement reduces @entity1 morbidity significantly compared with an open approach.
