Prevalence and childhood antecedents of XXXX in a UK birth cohort.

@entity1 @entity308 @entity148 @entity751 @entity204 @entity734
PURPOSE: @entity751 is characterised by a sense of unreality about the self [depersonalization (DP)] and/or the outside world [derealization (DR)]. Prevalence estimates vary widely. Little is known about childhood antecedents of the disorder although @entity734 is thought to play a role. METHODS: Longitudinal data from 3,275 @entity1 of a UK population-based birth cohort (the MRC National Survey of Health and Development) were used to: (1) assess the prevalence of @entity751 at age 36, measured by the Present State Examination (PSE); and (2) examine the effects of a range of socio-demographic, childhood adversity and emotional responses as potential risk factors for DP. RESULTS: Thirty three survey members were classified with DP, yielding a prevalence of 0.95% [95% confidence intervals (CI) 0.56-1.34]. There were no associations with socio-economic status, parental @entity204 or divorce; self-reported accidents, @entity308 , tendency to daydream or reactions to criticism. However, teacher-estimated childhood @entity148 was a strong independent predictor of adult depersonalization, and there were strong cross-sectional relationships between DP and @entity148 and @entity308 caseness. CONCLUSIONS: To our knowledge this is the first study assessing nationwide prevalence of the @entity751 and uses longitudinal data to explore childhood risk factors for adult DP. The prevalence of adult DP was slightly lower than reported by other surveys. The study found that childhood @entity148 was the only significant predictor of the adult @entity751 , supporting the view that depersonalisation disorder forms part of the spectrum of responses to @entity148 .
