Laparoscopic Nephrectomy versus Open Nephrectomy for XXXX with @entity8 : A Systematic Review and Meta-Analysis.

@entity1 @entity8 @entity190 @entity353
OBJECTIVE: To compare efficacy and safety of laparoscopicnephrectomy (LN) versusopen nephrectomy (ON) in the management of @entity8 ( @entity8 ), we conducted a systematic review and meta-analysis. METHODS: A systematic search of the electronic databases PubMed, Scopus, and the Cochrane Library was performed up to October 2014.This systematic review was performed based on observational comparative studies that assessed the two techniques. The @entity353 ( @entity353 ) and risk ratio (RR), with their corresponding 95% confidence interval (CI), were calculated to compare continuous and dichotomous variables, respectively. RESULTS: Seven studies were identified, including 195 cases (118 LN / 77 ON). Although LN was associated with longer operative time ( @entity353 30.236, 95%CI 14.541 -45.932, P<0.001) and the specimen might not have been resected as heavy as the ON group ( @entity353 -986.516, 95%CI -1883.24--89.795, P = 0.031), @entity1 in this group might benefit from a shorter length of hospital stay ( @entity353 -3.576, 95%CI 4.976--2.176, P <0.001), less estimated @entity190 ( @entity353 -180.245, 95%CI -317.939--42.556, P = 0.010), and lower need of transfusion (RR 0.345, 95%CI 0.183-0.650, P = 0.001). The LN group also had less overall complications (RR 0.545, 95%CI 0.329-0.903, P = 0.018). The need of narcotic analgesics between the two groups might have no significant difference ( @entity353 -54.66, 95%CI -129.76-20.44, P = 0.154). CONCLUSION: LN for giant symptomatic @entity8 was feasible, safe and efficacious. Morbidity was significantly reduced compared with the open approach. For an experienced laparoscopist, LN might be a better alternative.
