Keeping kidneys safe: The pharmacist's role in NSAID avoidance in high-risk XXXX .

@entity1 @entity5018 @entity740 @entity810
Objective: To provide information on the role of pharmacists in nonsteroidal anti-inflammatory drug (NSAID) avoidance in high-risk @entity1 . Summary: Nonprescription analgesics such as @entity5018 and naproxen are widely used by Americans. These nonsteroidal anti-inflammatory drugs (NSAIDs) are available in large quantities in pharmacies and also in wholesale stores, gas stations, and convenience stores. In addition, more than 111 million @entity1 use prescription NSAIDs each year, including many older Americans. NSAIDs may seem innocuous, but they carry a significant risk of disrupting blood flow to the kidneys and thus precipitating @entity810 ( @entity810 ). Episodes of @entity810 can lead to costly hospitalizations and long-term consequences such as new-onset @entity740 ( @entity740 ) or more rapid progression of existing @entity740 . Most cases of NSAID-induced @entity810 can be avoided by recognizing high-risk @entity1 and counseling them on appropriate use of these medications. Community pharmacy-based NSAID counseling and education at the point of prescription dispensing or nonprescription purchase could complement and augment NSAID-induced @entity810 education provided by other members of the health care team to high-risk @entity1 . Conclusion: NSAID use is widespread and severely compromises effective renal perfusion in high-risk @entity1 . The community pharmacist can play a pivotal role in NSAID avoidance education to prevent potential episodes of @entity810 that have long-term consequences for @entity1 .
