Serial analysis of the apparent diffusion coefficient time course in XXXX @entity64 .

@entity1 @entity64 @entity2806 @entity63 @entity4 @entity1188 @entity35925 @entity385
Acute @entity2806 can be rapidly detected on diffusion-weighted images. The apparent diffusion coefficient ( @entity35925 ) depends on the stage of cytotoxic @entity4 and water content in the infarcted parenchyma. The purpose of this study is to determine the time course of @entity35925 during the first days of @entity385 . These data should make it possible to distinguish between multiple @entity64 and a single progressive @entity1188 . Eight @entity1 with clinically diagnosed @entity2806 were examined by diffusion-weighted MRI from 2 to 20 h after onset of symptoms. Daily control scans were performed for up to 10 days. @entity35925 values were analyzed from 55 MRI studies. Furthermore, @entity35925 was measured in the tissue which showed a hyperintense signal at the first examination and in the contralateral tissue. White and gray matter were analyzed separately. Data were expressed as the ratio @entity35925 ( @entity35925 ) of lesion to control region of interest. All @entity1 showed a uniform reduction in @entity35925 from the first hours of @entity64 and decreasing to the 3rd day. The @entity35925 increased again from the 4th day up to the point of pseudo-normalization on day 9. The gray matter showed a slightly faster increase than the white matter. @entity35925 shows significant changes in the first days after @entity64 , following a rather uniform time course. Together with T2-weighted MRI this makes it possible to differentiate between hyperacute, acute, and @entity64 . Furthermore, the age of an @entity63 can be determined and @entity64 can be distinguished from a single progressive @entity64 .
