Prevalence of interrelated autoantibodies in thyroid diseases and XXXX .

@entity1 @entity2835 @entity5787 @entity6 @entity2743 @entity1669 @entity2621 @entity409 @entity934 @entity1252 @entity1737 @entity792 @entity775
OBJECTIVE: We determined the autoantibody profile in @entity1669 ( @entity1669 ) and examined the distribution of thyroid-related autoantibodies in other @entity792 . METHODS: We tested sera from 234 @entity1 with @entity2743 ( @entity2743 ), 130 with @entity2621 ( @entity2621 ), 249 with other @entity792 , and 50 healthy controls by enzyme-linked immunosorbent assay or radioimmunoassay. RESULTS: Autoantibodies except TSH receptor antibody (Ab), anti-thyroglobulin (Tg) Ab and @entity5787 ( @entity5787 ) Ab were not significantly prevalent in @entity1 with @entity1669 despite a significantly high elevation of thyroid-related Ab. Significant prevalence of autoantibodies related to @entity1669 was observed in type 1 @entity6 @entity1 . Elevation of anti-Tg Ab was seen in @entity1 with @entity2835 ( @entity2835 ) and @entity775 ( @entity775 ), and anti- @entity5787 Ab was elevated in @entity1 with @entity2835 . Although the prevalence of anti- @entity934 receptor Ab and @entity1252 ( @entity1252 )- related Ab was significant in @entity775 , primary Sj  gren's syndrome (pSS)-related Ab were also found in both @entity409 . In @entity1737 ( @entity1737 ) @entity1 , thyroid-related Ab and pSS-related Ab were detected in both @entity1737 groups, although @entity1252 -related Ab were limited to the anti-muscle specific kinase Ab-positive @entity1737 @entity1 . In @entity1 with connective tissue diseases, anti- Tg Ab and anti- @entity5787 Ab were significantly prevalent. CONCLUSION: Thyroid-related Ab were significantly elevated in all @entity792 . Conversely, the elevations of Ab were not significant in the @entity1 with @entity1669 , suggesting a close relationship between @entity1669 and other immune-mediated diseases.
