Evaluation of an implementation of XXXX maintenance treatment in China.

@entity1 @entity4784 @entity734 @entity284
BACKGROUND: @entity284 maintenance treatment (MMT) reduces the harms of @entity4784 and is being rapidly scaled-up in China. This study evaluated the real-world implementation of MMT system in Wuhan, China. METHODS: Data extracted from electronic medical records collected in 2010 on 8811 @entity1 were used to compute for each @entity1 indices of the prescribed and consumed daily @entity284 doses, an adherence index, dose adjustments following missed doses, the rates of opiate positive urine tests, self-reported drug use, @entity734 ( @entity734 ), and the duration of MMT exposure. FINDINGS: The modal daily doses prescribed were 60mg and above for 68.5% of @entity1 . Adherence was variable: 51% of @entity1 attended less than 60% and 26% attended 80-100% of their treatment days; and @entity1 with long MMT exposure had significantly higher adherence rates than @entity1 with short MMT exposure. The differences between doses dispensed immediately before and after the interruption in dosing days ranged from 0 to 7mg, independently of the length of the interruption or the prescribed dosing level. The overall rate of opiate positive tests was 20%; 45% of @entity1 had at least one opiate positive test; 29% reported past month drug use and 53% of them reported past month @entity734 . Adherence and MMT exposure duration correlated significantly with the proportion of opiate negative urine tests (r=0.355, p<0.001; r=0.351, p<0.001, respectively). Treatment for males and females was comparable. CONCLUSIONS: Provision of safe @entity284 dosing after absences and improving daily attendance are identified as priority improvement areas.
