Clinical courses of primary XXXX : retrospective analysis of eight cases.

@entity1 @entity96 @entity5 @entity2695 @entity409 @entity189 @entity157 @entity99
BACKGROUND/AIMS: @entity99 , a rare and aggressive @entity409 , is difficult to diagnose because of a lack of specific clinical features. The clinical and radiological features of @entity1 with histologically confirmed @entity99 were examined. METHODS: Among 2,336 @entity1 diagnosed with primary @entity96 at Keimyung University Dongsan Medical Center (Daegu, Korea) between May 2002 and February 2012, eight (0.03%) with histologically confirmed primary @entity99 were included. The patterns of disease diagnosis, @entity5 characteristics, treatment responses, and prognoses were reviewed retrospectively. RESULTS: Median age was 66 years-old (range, 41-80 years). Four @entity1 were male. Five @entity1 were compulsive drinkers. All @entity1 had no HBsAg and anti-HCV. Initial radiologic diagnoses revealed primary @entity99 (n=2), @entity157 (n=2), @entity2695 (n=2), and hepatic @entity189 (n=2). Definitive diagnoses were made by percutaneous needle biopsies in seven @entity1 and surgical resection in one @entity1 . At the time of the initial diagnosis, extrahepatic metastases were detected in three @entity1 (37.5%). Metastatic sites included the spleen and lung, pericardium, and bone, in one @entity1 each. Two @entity1 underwent conservative treatments. The remaining @entity1 underwent surgical resection (n=1), transcatheter arterial chemoembolization (n=1), and systemic chemotherapy (n=4). The median survival period was 214 days (range, 21-431 days). CONCLUSIONS: @entity99 is a highly progressive disease with a poor prognosis. Detailed studies including histological examinations are essential to facilitate early diagnosis of the disease.
