Increased risks of upper tract XXXX in male and female chinese herbalists.

@entity3675 @entity5 @entity42845 @entity189 @entity150 @entity703
BACKGROUND/PURPOSE: It has been shown that herbs that contain @entity42845 induce @entity5 . Chinese herbalists have easy access to such herbs. Our previous mortality study has shown a significantly increased risk of @entity5 in female but not male herbalists. To re-examine this risk in male herbalists, the incidence of @entity5 was analyzed. METHODS: We enrolled all 6550 Chinese herbalists in Taiwan registered during 1985-2000, and we retrospectively followed the development of @entity5 until 2001 by analysis of data collected from the Taiwan Cancer Registry. Standardized incidence ratios (SIRs) were calculated for @entity5 in herbalists and compared with those for the general population in Taiwan. RESULTS: There were 30 newly diagnosed cases of @entity5 and most of them were transitional cell @entity189 (93.1%). The mean age at diagnosis for @entity189 was 51.6 years, and 51.9% were in the upper urinary tract. After adjustment for age and sex, the SIR for all @entity5 was 3.51 [(95% confidence interval (CI): 2.37-5.01]. When stratified by location, the @entity703 and @entity150 were 4.24 (95% CI: 2.47-6.80) and 2.86 (95% CI: 1.52-4.89), respectively. When analyzed by sex, the SIRs for all @entity5 , @entity703 , and @entity150 were also significantly increased in male herbalists. CONCLUSION: The significant risk of @entity189 noted in male herbalists increases our suspicion that this is an @entity3675 that renders regular health assessment of herbalists an urgent necessity.
