Alterations in QT interval in XXXX undergoing living donor liver transplantation.

@entity1 @entity1344 @entity1165 @entity254 @entity299 @entity1575 @entity1162 @entity943
BACKGROUND: QT interval prolongation, predisposing to @entity1165 , has frequently been observed in @entity1 with @entity1575 . During liver transplantation (LT) surgery, electrolyte imbalance and @entity1344 may affect QT interval changes. We evaluated the alterations in QT parameters at each stage of LT surgery. METHODS: We assessed 50 living donor LT recipients without overt @entity299 for the corrected QT (QTc) and the interval from peak to the end of the T wave (T(p-e)) automatically using Bazett's formula with LabChart software. QT parameters, laboratory and hemodynamic data were simultaneously collected in the following stages of LT: before anesthetic induction (baseline), pre-anhepatic, anhepatic, 1 hour postreperfusion, and after hepatic artery @entity254 . Recipients were allocated into 2 groups according to their baseline QTc: >= 440 versus <440 msec. RESULTS: QTc progressively rose from the pre-anhepatic stage remaining prolonged in each stage of LT surgery compared with the baseline. In the anhepatic stage, 54% of recipients showed marked prolongation of QTc >= 500 msec (522    14), which indicated the potential for a fatal @entity943 : 77% and 36% in groups with QTc >= 440 and <440 msec, respectively. As opposed to changes in QTc, T(p-e) in the anhepatic stage decreased significantly; however, it returned to the baseline level in the neohepatic stage. CONCLUSION: A @entity1162 (>= 500 msec) was frequently observed throughout the procedure of LT, even among @entity1 with baseline QTc <440 msec, emphasizing the importance of optimizing electrolyte balance and hemodynamic status to reduce greater risk of perioperative @entity943 .
