A simple modification in operative technique can reduce the incidence of XXXX after orthotopic liver transplantation.

@entity1 @entity63 @entity935 @entity253 @entity850
@entity850 after liver transplantations are a source of significant morbidity, often necessitating retransplantation. The purpose of this study was twofold: first to identify features associated with the development of this lesion; second, to make technical modifications that will decrease the incidence of this problem. In the first part of this study, 15 of 131 @entity1 were diagnosed with @entity253 . A stepwise logistic-regression analysis associated donor cold ischemic time and @entity935 dose with the development of @entity253 . All these @entity1 had arterial reconstruction after partial revascularization of the liver with portal venous blood. Because the bile duct receives its blood supply from only the hepatic artery, we hypothesized that the prolonged period of warm @entity63 from staged reconstruction of the vascular supply would promote the development of this lesion. In a second part of this study, the stricture rate in 45 @entity1 with simultaneous revascularization using both the hepatic artery and portal vein was compared with that in 83 @entity1 from the first part of this study initially revascularized with portal venous blood. All @entity1 in the second study had grafts preserved using UW solution. Only 1 @entity1 with simultaneous revascularization developed a @entity253 . Because we were unable to identify any significant complications related to this method of revascularization, we propose that the hepatic artery and portal vein should be released simultaneously, especially in @entity1 receiving a graft with prolonged storage time.
