Analysis on therapeutic outcomes and prognostic factors of XXXX : a report of 49 clinical cases in a single center.

@entity9128 @entity1 @entity1276 @entity146 @entity5
UNASSIGNED: Although @entity9128 is relatively rare, it is often associated with great clinical @entity146 and poor overall survival. There are controversies over factors affecting the prognosis of the disease. The aim of this retrospective study was to evaluate factors that may affect the therapeutic outcome and prognosis of @entity9128 by reviewing the medical records of 49 @entity1 who were surgically treated in our hospital between 2001 and 2014. Univariate and multivariate analyses were performed to identify prognostic variables relative to @entity1 and @entity5 characteristics, and treatment modalities. All 49 @entity1 (24 @entity1 and 25 @entity1 ; mean age 27.6  years) underwent surgical resection, of whom 14 @entity1 also underwent postoperative radiotherapy. Local recurrence was found in 15 (48.8  %) @entity1 , and 22 (51.2  %) @entity1 died during the follow-up periods. The 5-year recurrence rate was 65  % and the survival rate was 51  %. The results of statistical analysis suggested that preoperative extraventricular drainage and surgical resection extent were prognostic factors related to progression-free survival, and that age, surgical resection extent and histological grade were closely associated with survival. Interestingly, there was a significant correlation between the symptom of @entity1276 and age (P  =  0.010), and @entity1 with a better clinical status (KPS  >=   80) were significantly associated with a lower WHO grade (P  =  0.007). In conclusion, we confirmed that surgical resection extent was the major independent factor affecting both recurrence and survival of @entity1 with @entity9128 , while age and WHO grade were prognostic factors affecting survival but not recurrence.
