The influence of adjuvants on local recurrence rate in XXXX of the bone.

@entity1 @entity5 @entity1777 @entity3971 @entity358 @entity3
INTRODUCTION: Intralesional surgery of @entity5 of the bone ( @entity1777 ) may result in a high rate of local recurrence. The introduction of local adjuvants, such as cementation, cryosurgery or phenolization, has proved to be successful in the reduction of recurrence rates. This study presents the results of a single institution in surgery of @entity1777 with an evolution in treatment strategies. MATERIAL _ METHODS: Forty primary and 25 recurrent surgical procedures in 46 @entity1 with @entity1777 of the bone with a median follow-up of 72 months were reviewed retrospectively. The mean age was 32.6 years (range 13.6-57.9 years). Forty-seven curettages and 18 resections were performed. For the curettages, a large bone window was cut followed by high speed burring and bone grafting or cementation. In 34 of 47 curettages and 7 of 18 resections, @entity3971 was additionally applied. RESULTS: Two @entity1 showed @entity358 , one died due to @entity3 . In total, a third of the @entity1 developed local recurrence (32.3%). This was evenly spread among primary and recurrent diesease (32.5% vs. 32%). Seven of 13 curettages without adjuvant recurred (53.9%), compared to 11 of 34 curettages with adjuvant @entity3971 (32.4%). Three of 18 resections developed a recurrence (16.7%). No complications in respect to the use of @entity3971 were seen. DISCUSSION: Phenolization is a safe local adjuvant therapy for @entity1777 . Although the recurrence rate was lower with the use of @entity3971 , this drop was not significant. The comparable high recurrence rate in our study, even if @entity3971 was used, might be due to the fact that curettage was our favoured treatment, even in cases with an extensive @entity5 . We recommend adjuvant phenolization in the treatment of @entity1777 of the bone after thorough curettage in applicable cases, including where cementation is used for defect filling.
