[Pregnancy and labor following kidney transplantation with XXXX . Case report and review of the literature].

@entity1 @entity821 @entity851 @entity600 @entity177 @entity205 @entity1011 @entity631
We report on a 22-year old @entity1 who received a cadaveric renal transplant following haemodialysis treatment for five months due to endstage chronic @entity631 . 14 months after successful transplantation while on stable renal function (serum- @entity1011 1.0-1.4 mg%) the @entity1 became pregnant. As an immunosuppressive therapy the @entity1 got @entity205 and @entity821 . The monitoring of the immunosuppressive therapy ( @entity205 ) was performed by daily measurement of serum concentration by radioimmunoassay. Drug administration was adjusted to maintain serum levels of 250-550 ng/ml. Increased dosages were required from 25th week until delivery. Until the 25th week of gestation the pregnancy was uncomplicated from both the nephrological and obstetrical points of view. At the 25th week of gestation the @entity1 became anuric. This was caused by a @entity177 due to the compression of the transplantar ureter by the pregnant uterus. Nephrostomy was installed and was used until the end of pregnancy. In the third trimester the foetus showed @entity851 . For this reason a Caesarean section was necessary at the 36th week of gestation. A healthy @entity1 was delivered weighing 2080 g and measuring 45 cm. No @entity600 were observed, the chromosomal analysis showed no aberrations. After the delivery @entity205 concentrations in the blood of the mother and the newborn were simultaneously measured. A remarkable difference in these concentrations was observed particularly in the mother's blood 864 ng/ml whereas in the baby's blood the concentration was 312 ng/ml. Three days after the delivery the @entity1 was able to urinate normally so that the nephrostomy could be removed.
