Serial transvaginal sonographic findings of cervical ectopic pregnancy treated with high-dose XXXX .

@entity1 @entity4181 @entity75 @entity3566 @entity1500 @entity5849 @entity1499
OBJECTIVE: We analyzed transvaginal sonographic findings from @entity1 with cervical @entity5849 treated with high-dose @entity1499 ( @entity1500 ). METHODS: This was a retrospective analysis of cervical pregnancies diagnosed in our institution from 1996 through 2006. We divided the cases into an @entity1500 treatment group and a surgical treatment group. We included cases treated with high-dose @entity1500 alone. We analyzed 9 cervical @entity5849 treated with @entity1500 , which was injected intravascularly at 100 mg/m(2) plus 200 mg/m(2) in 500 mL of a normal saline solution with @entity4181 rescue. The gestational sac sizes and serum human chorionic gonadotropin ( @entity3566 ) levels were periodically monitored to determine the resolution status. RESULTS: Fifty cervical pregnancies were diagnosed during the study period. Thirty cases were treated with @entity1500 , and 20 were treated with surgical procedures. Among the 30 cases in the @entity1500 treatment group, 9 had high-dose @entity1500 injection without surgical procedures. Cervical mass regression appeared at a median of 40 (range, 10-88) days after treatment, whereas the serum @entity3566 level decreased at a median of 14 (range, 9-17) days after treatment. The median time to complete regression of the cervical mass was 86 (range, 48-141) days, and the median time to complete regression of the serum @entity3566 level was 68 (range, 19-143) days. Cervical pregnancy was noted as a gestational sac at first but coexisted with a mixed @entity75 19 days after treatment. At 33 days after treatment, the cervical pregnancy was completely replaced by the mixed @entity75 . CONCLUSIONS: Resolution of the cervical mass on sonography lagged far behind resolution of the serum @entity3566 level. The cervical mass evolved from a gestational sac into a mixed @entity75 on serial transvaginal sonography.
