Metastatic @entity5606 of the parotid - Mimicking primary XXXX .

@entity41 @entity20027 @entity5 @entity242 @entity5606 @entity189 @entity1653 @entity14253 @entity2277 @entity3 @entity320 @entity5123
INTRODUCTION: @entity5 involving the parotid are predominantly primary with metastatic lesions forming a miniscule population. @entity1653 metastasizing to the parotid is extremely rare and hence can often be mistaken for the more common primary @entity14253 . PRESENTATION OF CASE: A 59-year-old male presented with a swelling in the left parotid region. Fine needle aspiration cytology was suggestive of myoepithelial predominant @entity5123 . A superficial parotidectomy performed revealed a @entity5 composed of rhabdoid cells with abundant finely granular eosinophilic cytoplasm raising a possibility of @entity20027 . Immunohistochemistry for myoepithelial markers was negative. A critical review elicited a history of surgical excision of a recurrent @entity5606 twice. A possibility of @entity3 was considered and a second panel of immunomarkers demonstrated @entity2277 and epithelial membrane antigen positivity. Neuroimaging studies demonstrated a space occupying lesion in the frontal lobe suggestive of a recurrent/ @entity41 . In view of the history, neuroradiology, histopathology and immunohistochemistry, a final diagnosis of metastatic @entity5606 to the parotid was rendered. DISCUSSION: Morphologically, metastatic @entity5606 may mimic a primary or @entity189 , @entity320 and @entity242 . Accurate diagnosis can be made by careful clinical evaluation and histopathological examination of the @entity5 . These @entity5 are composed of rhabdomyoblast like cells with abundant eosinophilic cytoplasm. The present case demonstrated characteristic histopathological features confirmed by immunohistochemistry. CONCLUSION: @entity5606 is an aggressive @entity5 with a high propensity to recur and metastasize. The present case highlights the importance of clinical, radiological and histopathological correlation to accurately diagnose these rare entities.
