XXXX and memory outcome following temporal lobe surgery: selective compared with nonselective approaches for @entity131 .

@entity1 @entity410 @entity131 @entity5494 @entity3808 @entity1315
OBJECT: The aim of this study was to compare @entity410 and memory outcome in @entity1 with medically refractory mesial @entity1315 due to @entity131 (MTLE/HS) treated using an anterior temporal lobectomy (ATL) or a selective amygdalohippocampectomy (SA). METHODS: Surgical outcome data were prospectively collected for 2 to 11 years in 161 consecutive @entity1 with MTLE/ HS. Eighty @entity1 underwent an ATL and 81 an SA. @entity410 control achieved with each technique was compared using the Engel classification scheme. Postoperative memory testing was performed in 86 @entity1 (53%). At the last follow up, 72% of the @entity1 who had undergone an ATL (mean follow up 6.7 years) and 71% of those who had undergone an SA (mean follow up 4.5 years) were @entity410 free (Engle Class IA). Estimated survival in @entity1 in Engel Classes I, IA, and I and II combined did not differ between the two surgical techniques. Preoperatively, 58% of the @entity1 had verbal memory scores one @entity5494 ( @entity5494 ) below the normal mean. One third of the @entity1 with preoperative scores in the normal range worsened after surgery, although this outcome was not related to the surgical technique. In contrast, one third of those whose preoperative scores were less than -1 @entity5494 experienced improvement after surgery. Nine (18%) of the 50 @entity1 whose left side had been surgically treated improved their verbal memory scores by more than one @entity5494 . Seven (78%) of these nine underwent an SA (p = 0.05). CONCLUSIONS: Both ATL and SA can lead to similar favorable @entity410 control in @entity1 with MTLE/HS. Preliminary data suggest that postoperative verbal memory scores may improve in @entity1 who undergo selective resection of a @entity3808 hippocampus in the dominant temporal lobe.
