Fat-saturated post XXXX T1 imaging of the brain in @entity15 .

@entity1 @entity2287 @entity15
BACKGROUND: Magnetic resonance imaging (MRI) is of vital importance in the diagnosis and follow-up of @entity1 with @entity15 ( @entity15 ). Imaging sequences better demonstrating enhancing lesions can help in detecting active @entity15 plaques. PURPOSE: To evaluate the role of fat-saturated @entity2287 -enhanced T1-weighted (T1W) images of the brain in @entity15 and to assess the benefit of performing this additional sequence in the detection of enhancing lesions. MATERIAL AND METHODS: In a prospective study over a six-month period, 70 consecutive @entity1 with clinically diagnosed @entity15 were enrolled. These constituted 14 male and 56 female @entity1 between the ages of 21 and 44 years. All the @entity1 underwent brain MRIs on a 1.5 Tesla Magnet. @entity2287 -enhanced T1 images with and without fat saturation were compared and results were recorded and analyzed using a conspicuity score and McNemar test. RESULTS: There were a total of 157 lesions detected in 70 @entity1 on post-contrast T1W fat-saturated images compared with 139 lesions seen on the post-contrast T1W fast spin-echo (FSE) images. This was because 18 of the lesions (11.5%) were only seen on the fat-saturated images. In addition, 15 lesions were more conspicuous on the fat saturation sequence (9.5%). The total conspicuity score obtained, including all the lesions, was 2.24 +/-0.60 (SD). Using the two-tailed McNemar test for quantitative analysis, the P value obtained was <0.0001. CONCLUSION: T1W fat-saturated @entity2287 -enhanced images show better lesion enhancement than T1W images without fat saturation.
