Residual @entity2661 in extrinsically denervated XXXX ileum.

@entity935 @entity1425 @entity840 @entity2515 @entity4478 @entity2661 @entity1063
1. Concentrations of @entity1063 , @entity1425 and @entity935 were measured in the submucosa and myenteric plexus of innervated and extrinsically denervated @entity840 ileum using a sensitive radioisotope enzymatic assay for @entity2661 . 2. Subcellular fractionation studies indicated that the microsomal fraction obtained from both layers of the normal ileum was greatly enriched with @entity1063 compared to the total homogenate. Low levels of @entity1425 and @entity935 were also detected in both layers of the ileum. 3. After extrinsic denervation or pretreatment with @entity2515 , @entity1063 was reduced to less than 3% and could no longer be visualized histochemically. Small proportions of the @entity1425 and @entity935 also disappeared after extrinsic denervation. 4. The residual amounts of @entity1063 , @entity1425 and @entity935 present after extrinsic denervation were not sensitive to @entity2515 and were not concentrated in microsomal fractions suggesting that these @entity4478 are not stored as neurotransmitters in intrinsic neurons of the intestine.
