The effects of XXXX and @entity5633 in light and moderate female social drinkers.

@entity1 @entity5633 @entity988 @entity1245 @entity1401 @entity19354
Individuals who are moderate/heavy drinkers are at increased risk to abuse @entity1245 and this risk is increased in @entity1 compared to @entity1 . However, no studies have determined whether female @entity19354 ( @entity19354 ) show a differential response to the subjective and performance effects of @entity1245 compared to female light drinkers (LD). Fourteen female @entity19354 who consumed an average of 36 drinks/month were compared to 14 female LD who consumed an average of 4.2 drinks/month. None of the @entity1 had either a first- or second-degree family history of @entity988 . The acute effects of placebo, @entity1401 (0.25, 0.50, 0.75 mg) and @entity5633 (5, 10, 15 mg) were evaluated using a double-blind, placebo-controlled outpatient design. Drug effects were assessed using a full range of performance measures and subjective-effects questionnaires. @entity1401 impaired performance in a dose-related manner on all performance tasks for both groups of females, whereas @entity5633 had minimal effects on performance. There were few differences between LD and @entity19354 with respect to subjective response or performance impairment following either @entity1401 or @entity5633 . Although @entity19354 reported greater ratings of Good Drug Effect and Drug Liking than LD, this was neither dose-related, nor specific to @entity1401 . The results of the present study suggest that female @entity19354 without a family history of @entity988 experience the same level of performance impairment as female LD, although they tend to report greater positive subjective effects from @entity1401 .
