Prognostic Factors of @entity1 with XXXX after Curative Resection: A Retrospective Analysis of 406 Consecutive Cases in a Multicenter Study.

@entity1 @entity5 @entity1820 @entity2467 @entity2280 @entity356 @entity674
BACKGROUND/PURPOSE: Gastric @entity674 ( @entity674 ) have a highly variable clinical course, and recurrent disease sometimes develops despite curative surgery. This study was undertaken to investigate the surgical role in treating @entity1820 and evaluate the clinicopathological features of a large series of @entity1 who underwent curative resection for @entity1820 to clarify which features were independent prognostic factors. METHODS: The clinicopathological data of 406 @entity1 with @entity1820 who underwent curative resection at 4 university hospitals in Daegu, South Korea, from March 1998 to March 2012 were reviewed. All cases were confirmed as @entity1820 by immunohistochemical staining, in which @entity2467 or @entity2280 was positive. Clinical follow-up was performed periodically, and disease-free survival rates were retrospectively investigated using the medical records. RESULTS: The mean follow-up period was 42.9 months (range: 2-166). There were 11 recurrent @entity1 (2.7%). Due to the small number of recurrences, age, sex and location were controlled using propensity score matching before performing any statistical analysis. @entity5 size, mitotic count, NIH classification, and cellularity were judged to be independent prognostic factors for recurrence by univariate analysis. In a multivariate analysis, @entity5 size and mitotic count were significantly and independently related to recurrence, and @entity5 size was determined to be the most important prognostic factor for recurrence after curative resection (hazard ratio: 1.204; p < 0.01). CONCLUSIONS: The results of this multicenter study demonstrate that disease-free survival rates are good. @entity5 size was disclosed as the most important factor for recurrence in @entity356 @entity1 who underwent radical resection.    2015 S. Karger AG, Basel.
