The nasal passage of subjects with XXXX has a decreased ability to warm and humidify inspired air.

@entity32 @entity2023 @entity566 @entity565 @entity9590
We previously showed that individuals with @entity2023 ( @entity2023 ) had a reduced ability to condition air, which was improved by @entity32 . We hypothesized that individuals with @entity9590 ( @entity9590 ) would condition air like @entity2023 with @entity32 . Because individuals with @entity565 usually have @entity32 in the nose, we hypothesized that they would condition air like individuals with @entity9590 . We performed a prospective, parallel study on 15 normal subjects, 15 subjects with @entity2023 outside their @entity566 season, 15 subjects with @entity9590 , and 15 subjects with @entity565 . Cold, dry air (CDA) was delivered to the nose and the temperature and humidity of the air were measured before entering and after exiting the nasal cavity. The total water gradient (TWG) was calculated and represents the nasal conditioning capacity. The TWG in the @entity2023 group was significantly lower than that in normal subjects. There were no significant differences in TWG between the @entity9590 and normal groups. Subjects with @entity565 had a significantly lower TWG than did normal subjects. There was a significant negative correlation between TWG and Aas score in the group with @entity565 (r(s) = -0.8, p = 0.0007). Our data show that subjects with @entity565 have a reduced ability of the nose to condition CDA compared with normal subjects, but which is similar to @entity2023 out of season.
