Expression of the @entity1 endogenous retroviruse-W envelope gene syncytin in XXXX .

@entity1 @entity18341 @entity1204 @entity75 @entity46
BACKGROUND: None of the existing theories provides a satisfactory explanation of the development of @entity46 . One hypothesis that may lead to further clarification is that the expression of specific proteins of @entity1 endogenous retroviruses (HERVs) might influence the development of @entity75 . Such endogenous retroviral proteins include syncytin, coded by @entity18341 , which is associated with the physiological development of the placenta during pregnancy. This study investigated the influence of @entity18341 gene expression in @entity46 foci (EM) quantitatively at the RNA level. MATERIALS AND METHODS: Specific RNA expression of syncytin ( @entity18341 ) was investigated in various endometrial tissues from 42 @entity1 (with normal endometrium, postmenopausal endometrium, EM, and @entity1204 ). RNA was isolated from the tissue samples and transcribed into DNA using reverse transcriptase polymerase chain reaction. The resulting DNA fragments were analyzed using agarose gel electrophoresis and assessed quantitatively. RESULTS: Normalized syncytin expression was low in EM. In Histologically normal endometrium from @entity46 @entity1 , the expression of normalized syncytin was seven times higher in comparison with the histologically normal endometrium in the control group. CONCLUSIONS: @entity18341 syncytin expression apparently does not play a role in EM. However, it may possibly influence the development of @entity46 because of increased expression in normal endometrium in @entity46 @entity1 .
