A second generation of artificial XXXX (Biokpro II).

@entity1 @entity267 @entity4280 @entity13768 @entity29781 @entity736 @entity3225
The properties of a new second-generation colonizable artificial @entity267 were evaluated in @entity1 . The prosthesis consisted of a peripheral rim of a translucent microporous @entity29781 polymer (expanded @entity736 ) fused with the polymer of the central optic. The optic was made of medical-grade @entity13768 coated with @entity4280 . Its refractive power was 42.2 diopters and it measured 7.0 mm in diameter and 0.55 mm in thickness. The geometry of the optic was tested by high-frequency ultrasound and intraocular pressure and distensibility were measured in an artificial chamber. Prostheses were implanted in one eye of 13 @entity1 . The average follow-up was 6 months (range 3-9 months). Most of the eyes (11/13) were clinically stable after a 7 months follow up. Seven @entity1 had visual acuity improvements. Mean corrected final visual acuity was 20/200 (range, 20/30 to light perception). Five anatomical failures occured (two extrusions, two retroprosthetic membranes, one @entity3225 ). The new optical core, junction, and surface properties of the polymers offer many advantages, quicker colonization of the supporting skirt, and an optical core with a geometry similar to that of a normal @entity1 @entity267 . Epithelial cells did not migrate over the interface and optical core. It seems that formation of an epithelium over the artificial device is essential for the long-term stability of the implant.
