XXXX of the sphenoid bone: long-term follow-up of two cases after chemotherapy.

@entity632 @entity1 @entity5 @entity2967
BACKGROUND: @entity2967 rarely occur in the sphenoid bone. When they do occur in the base of the skull, surgical treatment is frequently difficult and therefore, the use of adjuvant therapy is important. However, there remains no optimal management regimen for @entity2967 of the sphenoid bone. CASE DESCRIPTION: Two cases of a @entity2967 involving the sphenoid bone that responded well to chemotherapy using @entity632 after a partial removal of the @entity5 are presented. In the first @entity1 , the @entity5 was partially removed via a transcranial subfrontal approach and a transnasal transsphenoidal approach. In the second @entity1 , the @entity5 was partially removed through a transcranial subfrontal approach. Both @entity5 demonstrated histologic features typical of @entity2967 . The @entity1 subsequently received adjuvant chemotherapy using @entity632 alone in the first @entity1 , and chemotherapy combined with radiotherapy in the second @entity1 . Partial regression of the @entity5 was later confirmed on a computed tomography (CT) scan after chemotherapy. In both @entity1 , @entity5 have been stable for more than 12 years despite an incomplete @entity5 . CONCLUSION: Based on the above findings, postoperative adjuvant chemotherapy using @entity632 may be effective for incompletely resected @entity2967 of the sphenoid bone.
