[Natural killer (NK) and lymphokine-activated killer (LAK) activities of a XXXX recovered from @entity150 , and the characteristics of LAK cells generated from lymphocyte subsets].

@entity1 @entity404 @entity5 @entity150 @entity4071 @entity10086 @entity405
NK and LAK activities of a @entity1 who recovered from @entity150 were determined. He was diagnosed in 1980 and operations, radiations and chemotherapies were repeated until 1986. Since 1987, a relapse has not been recognized, and he is now in a @entity5 free state. Recently, his very high NK and LAK activities were found. The percentage of @entity4071 + in his peripheral blood lymphocytes (PBL) was 52.9%, the @entity404 - @entity405 - @entity4071 + was 26.6% (17.5% and 12.1% in control, respectively). It seems likely that his @entity5 free condition may be related to these high killer activities. As a high number of @entity404 - @entity405 - cells were included in his PBL, it was possible to generate a @entity404 - @entity405 (-)-LAK and compare it with the @entity10086 . The @entity404 - @entity405 (-)-LAK exhibited higher killer activity which was maintained for a long period of the culture, and a strong adherence property against the cultured @entity5 cells. Whereas, the @entity10086 did not show such a high level of killer activity which decreased after two weeks into the culture. However, the @entity10086 in this @entity1 demonstrated higher killer activity against the auto- @entity5 cell line compared to what occurred with the control. A type of specific killing against auto- @entity5 cells may be contained in his @entity405 (+)-LAK, although the MHC-restrictive killing was not confirmed. It remains unclear why the killer activities increased in this @entity1 .
