Relationship between epicardial fat measured by 64-multidetector computed tomography and XXXX .

@entity1 @entity3979 @entity460 @entity299 @entity729 @entity453
BACKGROUND: Epicardial fat (EF) is the visceral fat of the heart deposited under the visceral layer of the pericardium and has the same origin as abdominal visceral fat, which is shown to be strongly related to the development of @entity453 ( @entity453 ). We measured the volume of EF (EFV) by 64-multidetector computed tomography (MDCT) and studied the relationship between EFV and the severity of @entity453 . HYPOTHESIS: Epicardial fat volume increases steeply in @entity1 with significant @entity3979 and in those with severe @entity729 . METHODS: We studied 197 @entity1 with suspected @entity453 who underwent 64-MDCT and coronary angiography. @entity299 (3.0 mm thick) from base to apex (30 to 40 slices per heart) were traced semiautomatically and EFV was measured by assigning Hounsfield units ranging from -30 to -250 to fat. RESULTS: Epicardial fat volume was 99.4    40.0 ml (range, 11.6 to 263.8 mL) and coronary artery @entity460 score (CACS) was 267.2    605.1 (range, 0 to 3780). There was a significant relationship between EFV and CACS (r=0.210, P=0.003). @entity1 with EFV >100 had a CACS that was significantly higher than in those with EFV <100 (384.0    782.0 vs 174.8    395.6; P = 0.016). The incidence of significant @entity453 was significantly higher in @entity1 with EFV >100 compared with those with EFV <100 (40.2% vs 22.7%; P=0.008). The EFV was significantly higher in @entity1 with severe @entity3979 and in those with severe @entity729 (CACS >400). CONCLUSIONS: Our results showed that EFV was associated with @entity453 , and EFV increased steeply in @entity1 with severe @entity3979 and in those with severe @entity729 .
