Mitochondrial volume densities in the smokeless XXXX -treated @entity25221 epithelium.

@entity286 @entity5072 @entity25221 @entity2383
OBJECTIVES: To compare the morphological changes and quantitative distribution of @entity2383 in the @entity25221 ( @entity25221 ) epithelium treated with smokeless @entity286 (ST). MATERIALS AND METHODS: Archives of experimental material from previously published studies (Ashrafi et al., 1992) were utilized. Animals in experimental group received moist ST (snuff) in their right pouch, 5 days weekly for 24 months, while no snuff was given to control group. After 24 months, the epithelial tissues were processed for electron microscopy study. Volume densities of @entity2383 were assessed by morphometry. MAIN OUTCOME MEASURES: Mitochondrial volume densities in the two groups, experimental vs control. RESULTS: In both control and experimental groups @entity2383 were concentrated between the nucleus and basal cell plasma membrane. A decrease in the mean mitochondrial volume density (Vvmit) was observed from the basal layer to the more superficial layers in both groups. The experimental @entity25221 displayed more @entity2383 than control, and the granular epithelial cell layer in experimental group showed significantly a higher mean Vvmit than the control group (P = 0.03). It was concluded that greater numbers of @entity2383 were retained in ST-treated granular cells of the @entity5072 epithelia than in the normal epithelium.
