An independent association of prenatal @entity308 with wheezing and @entity148 with XXXX in infancy.

@entity1 @entity483 @entity308 @entity2490 @entity148 @entity56 @entity484
BACKGROUND: Different maternal psychological states during pregnancy have been associated with wheeze- @entity2490 - @entity484 symptoms in @entity1 . However, previous studies were limited and it was unclear whether the type of prenatal psychological state was associated with a particular symptom. We examined the association of maternal @entity308 and @entity148 during pregnancy with wheeze- @entity2490 - @entity484 symptoms in infancy. METHODS: In a longitudinal birth cohort (GUSTO) of 1152 mother- @entity1 pairs, wheeze- @entity2490 - @entity484 symptoms in the @entity1 during the first year of life were collected by parental report. Maternal @entity308 and @entity148 symptoms were assessed at 26 weeks of gestation using the Edinburgh Postnatal Depression Scale (EPDS) and State Trait @entity148 Inventory (STAI). Logistic regression analyses were performed with adjustment for potential confounders. RESULTS: An increased risk of wheezing was found in @entity1 of pregnant @entity1 with probable @entity308 (EPDS >=  15) [odds ratio (OR) = 1.85 (95% confidence interval (CI) 1.10-3.12)], and an increased risk of @entity2490 was associated with maternal @entity148 [STAI state >=  41: OR = 1.42 (95% CI 1.04-1.93); STAI trait >=  43: OR = 1.38 (95% CI 1.01-1.88)]. After adjusting for known risk factors for the development of @entity56 , these associations remained significant [EPDS >=  15: adjusted OR = 2.09 (95% CI 1.05-4.19); STAI state >=  41: adjusted OR = 1.82 (95% CI 1.17-2.82); STAI trait >=  43: adjusted OR = 1.70 (95% CI 1.10-2.61)]. However, maternal psychological states were not associated with @entity483 . CONCLUSION: This study suggests that there may be an independent effect of prenatal @entity308 on wheezing and @entity148 on @entity2490 in infancy.
