Long-acting XXXX injection after endoscopic dilation of anastomotic @entity30 may improve the outcome: a retrospective case series.

@entity1 @entity384 @entity134 @entity30 @entity2713
BACKGROUND AND STUDY AIMS: @entity384 of @entity30 is widely practised, but may not result in long-term symptomatic benefit, leading to the need for repeat dilation or surgery. It is hypothesized that long-acting @entity134 injection into strictures after dilation may decrease the need for further @entity384 and improve the outcome in symptomatic @entity1 . @entity1 AND METHODS: @entity1 with @entity30 who have had @entity384 and @entity2713 injection performed for symptomatic anastomotic strictures were identified from endoscopy records. Case notes were reviewed to determine outcomes. RESULTS: Fourteen @entity1 underwent a total of 26 dilations, with @entity2713 injected (median dose 20 mg, 10-40 mg) in 20 of the procedures. Seven @entity1 (50%) had sustained remission after a single dilation and @entity134 injection, with a median follow-up period of 16.4 months (range 13.2-22.0 months). Four @entity1 (28.5%) required more than one dilation (median three dilations, range two to four) to control their symptoms, with a median follow-up period of 27.8 months (range 14-32.8 months). Endoscopic management failed in three @entity1 (21.4 %), who were referred for surgery. There were no complications due to dilation or @entity2713 injection. CONCLUSIONS: @entity2713 injection into the stricture after dilation is safe, easy to perform, and may be a useful adjunct in the management of anastomotic @entity30 . These data will require further support through a randomized and controlled trial.
