XXXX : an insight into their origin and clinical significance.

@entity706 @entity5 @entity957 @entity674 @entity356
@entity5 are rare @entity5 displaying two distinct cell populations developing in juxtaposition to one another without areas of intermingling. They are rare entities with only 63 cases described in English literature. @entity5 encountered are @entity356 colliding with @entity706 , @entity674 , @entity957 , and @entity5 . Their cell origin is obsolete by the time of diagnosis. Different tumorigenesis theories have been suggested to explain their behavior, yet none has managed to provide satisfactory explanation for all cases. Clinically they are indistinguishable from the dominant @entity5 . Lack of data does not allow detailed assessment of their behavior yet they seem aggressive @entity5 with dismal prognosis. The majority of cases have been diagnosed postoperatively during histologic examination of specimens. There are no guidelines or concrete evidence to support best way of adjuvant or other types of treatment. However, these rare @entity5 might help in unlocking secrets of @entity5 behavior including tumorigenesis, differentiation, and adhesion and thus clinicians should be aware of their existence.
