Variable responses of mitral valve motion and flow in systemic XXXX and in @entity1000 .

@entity1 @entity1000 @entity296 @entity101
The relation between transmitral flow and diastolic mitral valve motion were examined in 17 normal @entity1 , 14 @entity1 with @entity101 and 12 @entity1 with @entity1000 . M-mode echograms were analyzed for early and late diastolic mitral leaflet separations, their ratio and E-F slope. Pulsed Doppler transmitral flow was analyzed for early and late velocities, their ratio and early flow deceleration. Early diastolic mitral valve leaflet separation was reduced in @entity1 with @entity101 (at 28 +/- 5 mm [p less than 0.05] ) and in @entity1 with @entity296 (at 22 +/- 3 mm [p less than 0.01] ). Flow velocity was also reduced in @entity1 with @entity101 (at 52 +/- 11 cm/s [p less than 0.05] ) and in @entity1 with @entity296 (at 48 +/- 15 cm/s [p less than 0.01] ). However, early leaflet separation and flow velocity were not related (r = 0.26). Late diastolic leaflet separation was similar (at 25 +/- 5 mm) in normal subjects and in those with @entity101 (at 23 +/- 6 mm), but was reduced in @entity1 with @entity296 (at 18 +/- 3 mm [p less than 0.01] ). In contrast, late flow velocity was increased in @entity1 with @entity101 (at 52 +/- 12 cm/s [p less than 0.05] ) but unchanged in @entity1 with @entity296 (at 42 +/- 16 cm/s). The ratio of early to late leaflet separation was similar in all groups, whereas the ratio of flow velocities was reduced in @entity101 @entity1 . Neither the E-F slope not early flow deceleration was altered in either pathologic group. Thus, @entity101 and @entity296 had similar effects in early rather than late diastole.(ABSTRACT TRUNCATED AT 250 WORDS)
