Periprostatic Fat Thickness on MRI: Correlation With Gleason Score in XXXX .

@entity1 @entity263 @entity1486
OBJECTIVE. The purpose of this study was to retrospectively evaluate the relationship between periprostatic fat thickness on @entity263 using radical prostatectomy as the reference standard. MATERIALS AND METHODS. This study included 190 @entity1 (mean age [   SD], 66.9    7.0 years) who underwent MRI before radical prostatectomy. Two radiologists measured the subcutaneous and periprostatic fat thickness on midsagittal T2-weighted MR images as the shortest perpendicular distance from the pubic symphysis to the skin and prostate, respectively. Subcutaneous and periprostatic fat along with age, height, weight, body mass index, and @entity1486 ( @entity1486 ) were correlated with Gleason score by using Pearson (r) or Spearman (  ) correlation coefficients and compared between low- (Gleason score = 6) and high- (>=  7) grade @entity263 by using univariate and multivariate logistic regression analyses. RESULTS. The mean subcutaneous and periprostatic fat thicknesses were 24.0    8.4 mm and 5.0    2.0 mm, respectively. The Gleason score was significantly correlated with age (   = 0.181, p = 0.012), @entity1486 (   = 0.345, p < 0.001), and periprostatic fat thickness (   = 0.228, p = 0.002). Multivariate analysis revealed that age, height, @entity1486 level, and periprostatic fat thickness (odds ratio, 1.331; 95% CI, 1.063-1.666) were independently predictive of high-grade (p  <= 0.013) disease. CONCLUSION. Periprostatic fat thickness on MRI showed a mild to modest but significant correlation with @entity263 with radical prostatectomy as the reference standard and was an independent predictive factor for high-grade @entity263 .
