Does the XXXX level on the day of @entity1 chorionic gonadotropin administration predict the clinical outcome of controlled @entity43 ?

@entity1 @entity4396 @entity43 @entity1465 @entity53 @entity1176
OBJECTIVE: To investigate the effect of serum @entity53 (E2) levels on the day of @entity1 chorionic gonadotropin ( @entity1465 ) administration on the outcome of controlled @entity43 (COH) in both long @entity4396 ( @entity1176 ) agonist and @entity1176 antagonist protocols. MATERIALS AND METHODS: This study included 212 in vitro fertilization-embryo transfer (IVF-ET) cycles performed with either long @entity1176 agonist or @entity1176 antagonist protocols were classified into three groups according to serum E2 levels measured on the day of @entity1465 injection: < 2,000 pg/ml, 2,000-4,000 pg/ml, and > 4,000 pg/ml. The three groups were compared according to age, number of retrieved oocytes, number of transferred embryos, and pregnancy rates for each of the stimulation protocols. RESULTS: The long and antagonist protocols were performed in 130 and 82 cycles, respectively. The pregnancy rates were 21.5% (28/130) and 23.2% (19/82) in the long- and antagonist-protocol groups, respectively. Serum E2 levels were measured on the day of @entity1465 administration as < 2,000 pg/ml in 65 cycles, 2,000-4,000 pg/ml in 76 cycles, and > 4,000 pg/ml in 71 cycles. The number of retrieved oocytes increased in parallel to serum E2 levels (p = 0.001). However, there was no significant difference among groups in the pregnancy rates (p = 0.116). Similarly, the number of retrieved oocytes increased in parallel to serum E2 levels in both of the protocol groups (p value was 0.001 in both long @entity1176 agonist and antagonist protocols), but there was no correlation between the pregnancy rates and serum E2 levels (p value of long @entity1176 agonist protocol was 0.254 and thep value of antagonist group was 0.349). CONCLUSION: The serum E2 level on the day of @entity1465 administration does not predict the pregnancy outcome in IVF with either long @entity1176 agonist or @entity1176 antagonist protocols.
