Combined first-pass and equilibrium radionuclide ventriculography and comparison with left ventricular/right XXXX count ratio in @entity339 .

@entity1 @entity64 @entity339 @entity1284
Effective and total left ventricular (LV) @entity64 volume were assessed in 31 @entity1 with verified @entity339 , or both, and in 22 @entity1 with normal valvular function using combined first-pass and equilibrium radionuclide ventriculography. The difference between these 2 volumes as a fraction of LV @entity64 volume was taken as the radionuclide regurgitant fraction. The results were compared with the LV/right ventricular (RV) @entity64 count ratio and with the angiographic regurgitant fraction according to the method of Sandler and Dodge. Radionuclide regurgitant fraction derived from 2 determinations with a time interval of 1 week showed good reproducibility (n = 15, r = 0.96, SEE = 9.1). Sensitivity was 100% for radionuclide regurgitant fraction and 87% for LV/RV @entity64 count ratio at equal specificity (100%). Radionuclide regurgitant fraction was more sensitive, especially in severely ill @entity1 , in whom additional RV @entity1284 led to false-low or false-negative ratios. Angiographic and radionuclide regurgitant fraction showed linear correlation (r = 0.79, p less than 0.001). In contrast, because 5 @entity1 had RV @entity1284 , only a weak correlation could be noticed between angiography and LV/RV @entity64 count ratio (r = 0.47, p less than 0.05). Excluding these @entity1 , correlation substantially improved (r = 0.74, p less than 0.001). The combination of first-pass and equilibrium radionuclide ventriculography is a sensitive, specific and well reproducible method for the evaluation of @entity339 .(ABSTRACT TRUNCATED AT 250 WORDS)
