Dual Intervention to Increase XXXX Retesting: A Randomized Controlled Trial in Three Populations.

@entity1 @entity851 @entity1047
INTRODUCTION: @entity1047 retesting 3 months after treatment is recommended to detect reinfections, but retesting rates are typically low. The purpose of this study is to determine if the addition of a postal home collection kit to a @entity851 ( @entity851 ) reminder at 3 months increases the percentage of @entity1 retested for @entity1047 at 1-4 months, compared to @entity851 alone. DESIGN: In this unblinded randomized controlled trial, @entity1 were randomized 1:1 to intervention (home arm) or control (clinic arm) status. SETTING/ @entity1 : @entity1 included 200 each of @entity1 , heterosexual @entity1 , and @entity1 who have sex with @entity1 diagnosed and treated for @entity1047 at sexual health services. INTERVENTION: Three months after @entity1047 diagnosis, home arm @entity1 received an @entity851 reminder and postal home collection kit ( @entity1 , vaginal swab; heterosexual @entity1 , Copan UriSwab; @entity1 who have sex with @entity1 , UriSwab and rectal swab). MAIN OUTCOME MEASURES: The main outcome measures were the percentage of @entity1 retested at 1-4 months after @entity1047 diagnosis and the percentage in each arm with repeat positive tests, by risk group and overall, analyzed by intention to treat. Data were collected from 2011 to 2013 and analyzed in 2014. RESULTS: The percentage retested within 1-4 months of @entity1047 diagnosis was significantly higher in home versus clinic arm @entity1 among @entity1 (64% [66/103] vs 39% [38/97], p<0.001); heterosexual @entity1 (56% [57/101] vs 34% [34/99], p=0.002); @entity1 who have sex with @entity1 (62% [61/98] vs 44% [45/102], p=0.010); and overall (61% [184/302] vs 39% [117/298], p<0.001). The percentage in the home versus clinic arm with repeat positive tests was significantly higher among @entity1 who have sex with @entity1 (16% [16/98] vs 5% [5/102], p=0.021) and overall (10% [31/302] vs 4% [12/298], p=0.006). CONCLUSIONS: The addition of a postal home collection kit to routine @entity851 reminders resulted in substantial improvements in @entity1047 retesting rates in all three risk groups and detection of more repeat positive tests, compared with @entity851 alone. Extending the intervention to other primary care settings with low retesting rates should be considered.
