Keratin staining pattern in clinically normal and diseased oral mucosa of lichen planus XXXX .

@entity1 @entity32 @entity5115 @entity75 @entity1325 @entity29903 @entity2543 @entity12120 @entity8619
The keratin pattern in oral epithelia is related to the type of terminal differentiation observed morphologically (keratinization/nonkeratinization) and to the presence or absence of @entity5115 . Furthermore, it has been suggested recently that inflammatory phenomena influence the keratin expression in @entity1 gingiva. The aim of the present study was to describe the keratin pattern in @entity8619 , which are well known to be characterized by hyperkeratinization and severe inflammatory changes, in order to elucidate the role of @entity32 in keratin expression of oral epithelia. Tissue sections were stained with antikeratin antibodies directed to groups of keratins ( @entity1325 and @entity29903 ) and to single keratin proteins (Nos. 5, 8, 13, and 19). The keratin pattern in OLP lesions differed in some respects from that of @entity12120 and frictional keratoses as characterized in previous studies. No consistent patterns for use in a diagnostic context were found. However, the changes in OLP lesions did not mimic those previously described in inflamed gingival specimens and in @entity2543 . Thus, the results encourage further studies on the potential diagnostic use of keratin expression in @entity75 . Furthermore, the study suggests that the inflammatory reaction seen in OLP lesions does not influence keratin expression in a way comparable with the suggested influence of @entity32 in gingival specimens.
