The Differences in Ultrasound and Clinicopathological Features between Basal-Like and Normal-Like Subtypes of Triple Negative XXXX .

@entity1 @entity0 @entity5 @entity470 @entity189 @entity4205
PURPOSE: The aim of this study was to identify the ultrasound features and clinicopathological characteristics of basal-like subtype of @entity0 ( @entity0 ). MATERIALS AND METHODS: This study was approved by the ethical board of the Second Affiliated Hospital of Harbin Medical University. The @entity1 ' clinicopathological information was available. The ultrasound features of 62 @entity5 from 62 TNBC @entity1 were interpreted. The immunohistochemical results of cytokertain5/6 ( @entity4205 ) and @entity470 ( @entity470 ) were used to classify the @entity5 into basal-like and normal-like groups. The association of the ultrasound features interpreted by experienced ultrasound doctors with the immunohistochemical classification was studied. RESULTS: Of the 62 TNBC cases, 42 (67.7%) exhibited the basal-like phenotype and 20 (32.3%) exhibited the normal-like phenotype based on the immunohistochemical @entity4205 and @entity470 markers. Of all the @entity5 , 90.3% were invasive @entity189 . The basal-like @entity5 were significantly associated with a maximum diameter on ultrasound of more than 20 mm (36, 85.7%) (P = 0.0014). The normal-like @entity5 usually exhibited lateral shadows (15, 75%) (P = 0.0115) as well as microlobulated margins (12, 60%) (P = 0.0204) compared to the basal-like subtype. Other ultrasound features showed no significant differences between the two groups. CONCLUSIONS: Although ultrasound cannot yet be used to differentiate between the basal-like subtype and normal-like subtype of TNBC, ultrasound can be used to provide some useful information to the clinicians.
