Relationship Between XXXX and @entity73 in a Multiethnic Elderly Cohort.

@entity1 @entity7864 @entity6 @entity2204 @entity303 @entity73
OBJECTIVES: To examine the association between @entity6 and cognitive functioning at baseline and @entity73 over time in a large, ethnically diverse sample of older adults. DESIGN: Prospective cohort study. SETTING: Washington Heights-Inwood Columbia Aging Project, a community-based, prospective study of risk factors for @entity303 in northern Manhattan, New York City. @entity1 : Hispanic, @entity7864 , and non-Hispanic white @entity1 and @entity1 aged 65 and older without @entity303 at baseline (N  =  1,493). MEASUREMENTS: @entity1 underwent baseline and follow-up cognitive and health assessments approximately every 18  months. Generalized estimating equations were used to examine the longitudinal association between @entity6 and cognition. RESULTS: @entity6 was associated with poorer baseline cognitive performance in memory, language, processing speed and executive functioning, and visuospatial abilities. After adjusting for age, education, sex, race and ethnicity, and @entity2204 , @entity1 with @entity6 performed significantly worse at baseline than those without in language and visuospatial abilities. There were no differences between those with and without @entity6 in terms of rate of @entity73 over a mean follow-up time of 6  years. CONCLUSION: The rate of @entity73 in elderly @entity1 with and without @entity6 is similar, although cognitive performance is poorer in @entity1 with @entity6 . These findings suggest that cognitive changes may occur early during the @entity6 process and highlight the need for studies to follow @entity1 beginning at least in midlife, before the typical later-life onset of @entity303 .
