Indications for the surgical management of central nervous system XXXX .

@entity1 @entity4767 @entity410 @entity2379 @entity2380 @entity3102 @entity4034 @entity262 @entity177 @entity17101 @entity370
BACKGROUND: Blastomycotic @entity4767 (CNS) occur infrequently. The medical literature concerning @entity17101 of the CNS contains little information regarding indications for surgery. METHODS: We report five cases of CNS @entity17101 that required surgery: four intracranial and one intraspinal. One @entity1 had a prior diagnosis of @entity370 , whereas none of the others had been diagnosed with any other @entity262 . The @entity1 were evaluated with plain x rays as well as with computed tomography or magnetic resonance imaging. RESULTS: Four of these @entity1 had extradural abscesses that required surgical drainage as well as debridement of granulomatous tissue and infected bone. The remaining @entity1 had an intracerebellar abscess. Postoperatively, three @entity1 were treated with @entity2379 , one with @entity2379 and @entity3102 , and one with an experimental protocol of @entity2380 alone. All of the @entity1 recovered without sequelae of @entity410 , recurrence of disease, or reaction to pharmacotherapy, although one @entity1 had transient @entity177 due to @entity2379 . CONCLUSIONS: Our experience with CNS @entity17101 managed surgically is reported. We propose three general surgical indications for these @entity1 : mass lesions, diagnostic biopsy, and @entity4034 refractory to pharmacotherapy.
