Incidence and Risk Factors for Respiratory Complications in XXXX Undergoing Esophagectomy for Malignancy: A NSQIP Analysis.

@entity1 @entity55 @entity5 @entity1353 @entity1576 @entity1030 @entity285 @entity356
Respiratory complications are the most frequent adverse events in @entity1 undergoing esophagectomy for @entity5 , and their occurrence may negatively affect postoperative recovery and outcomes. We queried the American College of Surgeons National Surgical Quality Improvement Program dataset to study the rate and influence of @entity55 , unplanned intubation, and ventilator dependency >48 hours on the early outcomes after esophagectomy and risk factors for their development. We included adult @entity1 with an esophageal or @entity356 diagnosis who were treated with esophagectomy between 2005 and 2012 and grouped them into 2 categories with respect to development of @entity1576 . Early surgical outcomes (including 30-day mortality, overall morbidity, return to operating room, and length of hospital stay) were compared. Risk factors associated with @entity1576 after esophagectomy were assessed using modified Poisson regression. A total of 2945 @entity1 were identified and @entity1576 were observed in 687 (23.3%) of them. We observed a significant @entity1576 rates after esophagectomy throughout the studied years. @entity1 who developed @entity1576 were older and had more comorbidities and longer operative time. These @entity1 also had statistically significantly higher rates of 30-day mortality and overall morbidity and were more likely to return to the operating room and to stay in the hospital longer. On multivariable analysis, numerous factors, including advanced age, smoking, @entity285 use, @entity1353 , history of @entity1030 , and prolonged operative time, were found to be risk factors for developing @entity1576 . As the development of @entity1576 leads to worse early surgical outcomes after esophagectomy, efforts should be made to prevent their occurrence by identifying @entity1 with significant risk factors.
