Comparison of Angioseal and Manual Compression in XXXX Undergoing Transfemoral Coronary and Peripheral Vascular Interventional Procedures.

@entity1 @entity455 @entity4917
@entity455 ( @entity455 ) were introduced in the early 1990s with the goal of limiting the time, labor, bed rest, and @entity1 discomfort associated with manual compression (MC) for hemostasis after cardiovascular interventions. However, its advantage over MC has not been extensively studied after interventional procedures. The aim of this study was to do prospective, randomized study comparing the safety and efficacy of the @entity4917 ( @entity4917 ) to that of MC in @entity1 undergoing transfemoral coronary and peripheral vascular interventional procedure. A prospective, randomized trial was undertaken on consecutive series of @entity1 admitted to King Fahd Hospital of the University for transfemoral coronary and peripheral vascular interventional procedures over 1 year. The study was designed to compare the hemostasis time in minutes and the incidence of @entity455 in @entity1 receiving @entity4917 with those undergoing MC. All @entity1 were on antiplatelets and received heparin during the procedure. During the study period, 160 @entity1 were included, 80 in each group. There was a significant difference in mean time to hemostasis in minutes (15.83        1.63 minutes for MC and 0.42        0.04 minutes for the @entity4917 ; p   <   0.001), time to ambulation in minutes (280        15 for MC and 120 for @entity4917 ; p   =   0.04) and in minor complications (33.8% in MC vs. @entity4917 5%; p   <   0.001). However, the major complication rate did not significantly differ between the two groups (0% in @entity4917 vs. 2.5% in MC; p   =   0.15). @entity4917 was found to achieve rapid closure of the femoral access site safely in @entity1 undergoing coronary and peripheral vascular interventional procedures under antiplatelets and systemic heparinization.
