Guideline treatment results in regression of atherosclerosis in XXXX .

@entity1 @entity64 @entity6 @entity583 @entity543 @entity65
BACKGROUND: Efficacy of guideline @entity65 prevention regimens may differ between @entity1 with or without @entity6 . We therefore compared change in carotid artery wall dimensions in @entity6 and @entity6 @entity1 with a history of a major @entity65 event, using magnetic resonance imaging. METHODS: Thirty @entity6 @entity1 and 29 age- and sex-matched @entity6 @entity1 with a history of @entity64 or @entity583 and a @entity543 (15%-70%) were included. In all @entity1 , treatment was according to cardiovascular risk management guidelines. At baseline and follow-up, carotid artery vessel wall dimensions were measured using 1.5   T magnetic resonance imaging. RESULTS: After 2   years of follow-up, total wall volume of the carotid artery in @entity6 @entity1 decreased by 9.6% (p   =   0.016). In contrast, stabilization rather than regression of carotid artery wall dimensions was observed in @entity6 @entity1 over a 2-year period. Body mass index was identified as a predictor of total wall volume decrease. CONCLUSIONS: Guideline treatment arrests atherogenesis in @entity6 @entity1 and even decreases vessel wall dimensions in @entity6 @entity1 . Baseline body mass index predicts @entity65 prevention efficacy expressed as decrease in total wall volume. These data emphasize the importance of optimal cardiovascular-prevention, particularly in @entity6 @entity1 with a high body mass index.
