Mammographic morphology and distribution of XXXX in situ diagnosed in organized screening.

@entity1 @entity0 @entity513 @entity730 @entity400 @entity3
BACKGROUND: @entity513 in situ of the breast (DCIS) represents a challenge in mammographic screening due to its unknown progression into @entity3 . The majority of the DCIS is detected due to signs of @entity730 on the mammograms. PURPOSE: To analyze the combinations of mammographic morphology and distribution of @entity730 by Van Nuys nuclear grade (grade). MATERIAL AND METHODS: A total of 217 DCIS diagnosed in @entity1 aged 50-69 years old who participated in the Norwegian @entity0 Screening Program in the period November 1995 to December 2007 were reviewed by four breast imaging specialists. The mammograms were classified according to the morphology and distribution of the @entity730 , using BI-RADS nomenclature. Chi square test was used to compare the groups of morphology and distribution by grade. RESULTS: Calcifications were identified in 93% (202/217) of the cases, 15% (30/202) as grade 1 and 74% (149/202) as grade 3. Fine @entity730 were seen in 38% (77/202) of the lesions and fine linear and fine linear branching in 31% (62/202). Sixty-nine percent (53/77) of the fine pleomorphic and 84% (52/62) of the fine linear and fine linear branching @entity730 were high grade lesions. Grouped distribution was seen in about half of all the cases (104/202). Among the high grade lesions with fine @entity400 , 75% (40/53) and 69% (36/52), respectively, had grouped or segmental distribution. CONCLUSION: DCIS presented overlapping groups of morphology and distribution of calcification by grade, but fine @entity400 with grouped and segmental distributions were associated with high grade DCIS. Seeking for further knowledge that allows separation of non-high grade from high grade DCIS has to continue to improve the quality of mammographic screening.
