Prevalence of central sleep apnea during continous positive airway pressure (CPAP) titration in subjects XXXX at an altitude of 2640   m.

@entity1 @entity712 @entity387 @entity27 @entity519 @entity386
BACKGROUND: The occurrence of central apneas when applying positive pressure (CPAP) to @entity1 @entity27 ( @entity27 ) is @entity387 ( @entity387 ). This causes poor adherence to CPAP and persistence of symptoms. In Bogota, a city located at an altitude of 2640 m above sea level, chronic @entity519 can generate certain instability of the respiratory system during sleep which could increase the presence of central @entity386 . The aim was to establish the prevalence of central @entity386 (central @entity386 index   >5/h) in adults with moderate or severe @entity27 during CPAP titration, and the factors associated with this. METHOD: @entity1 over 18 years old with @entity27 were referred to the Fundacion Neumologica Colombiana Sleep Center, from January 2008 to June 2010. Polysomnogram (PSG) for CPAP titration was performed according to the American Academy of Sleep Medicine criteria. The prevalence was calculated and the clinical and baseline PSG factors associated with the @entity387 were analyzed. RESULTS: We included 988 @entity1 , 58% @entity1 . @entity387 prevalence was 11.6%. Factors associated with @entity387 were: central apneas in the baseline PSG (OR: 5.34 [3.49-8.16]), history of @entity712 (OR: 2.53 [1.58-4.07]), and male sex (OR: 1.68 [1.06-2.69]). CONCLUSION: The prevalence of @entity387 in Bogota (11.6%) was intermediate compared to the reported in lower altitudes. The factors associated with the development of @entity387 were male sex, @entity712 , and the presence of central @entity386 in the baseline PSG.
