Cost-effectiveness of @entity7548 ( @entity7548 ) glue injections versus XXXX in the management of @entity2312 .

@entity1 @entity548 @entity3126 @entity75 @entity3080 @entity5273 @entity1151 @entity7548 @entity2312 @entity204
The management of @entity548 gastric varices has not been standardized. Although @entity5273 ( @entity5273 ) is used in most centers, endoscopic treatment with @entity7548 ( @entity3080 ) glue has recently been shown to be effective. Cost-effectiveness analyses of these methods are lacking. METHODS: We performed a retrospective review of @entity1 with @entity548 gastric varices treated either by @entity5273 or @entity3080 glue injection. Economic analysis was based on direct costs for a fixed financial year. The two groups were compared for a period of 6 months follow-up, to liver transplantation, or @entity204 for each @entity1 . RESULTS: Between January, 1995 and December, 1999, 20 @entity1 with @entity548 gastric varices had @entity5273 ; 23 @entity1 had @entity3080 glue injection from January, 2000 to October, 2001. There were no significant differences between the two groups in @entity1 characteristics, transfusion requirement, and gastric variceal anatomy. In the @entity5273 group, 15/20 @entity1 had the procedure performed within 24 h of @entity548 , and 90% of stent insertions were successful. Complications consisted of two cases of @entity3126 , two cases of severe @entity75 , and a 15% stenosis rate at 6 months. In the glue group, there were 3 +/- 1.5 endoscopies and 2 +/- 1 injections per @entity1 , with a 96% initial hemostasis. There was one case of (glue) @entity1151 and one blocked front endoscope lens, which required repair. The initial rebleed rate was significantly lower in @entity1 who had @entity5273 (15% vs 30%, p = 0.005). The inpatient stay was shorter in the glue group (13 +/- 1 vs 18 +/- 2 days, p = 0.05), but there was no difference in the overall mortality rate. The median cost within 6 months of @entity2312 was  4,138 US dollars ( 3,009- 8,290 US dollars) for glue versus  11,906 US dollars ( 8,200- 16,770 US dollars) for @entity5273 (p < 0.0001). CONCLUSION: In this comparable group of @entity1 , @entity3080 glue injection was more cost effective than @entity5273 in the management of @entity2312 . A prospective, randomized trial would be required to confirm our analysis.
