[ XXXX : retrospective study of twenty seven cases].

@entity1 @entity5337 @entity5892 @entity15310 @entity14553 @entity49 @entity3459 @entity854 @entity4555 @entity1031 @entity74 @entity1129 @entity715
PURPOSE: Among the locations of @entity49 , even if rare, @entity5892 is a severe event with a high mortality rate. No aetiology is found in 20 to 30% of the cases. In recent years, @entity3459 have been described, as risk factors for @entity49 . We report the results of a retrospective study of 27 @entity1 who suffered @entity5892 , in which @entity854 have been searched for. METHOD: The @entity1 were referred to the haemostasis laboratory of the Henri Mondor hospital between august 1982 and June 1988, after a @entity5892 . The predisposing factors, personal and family history of @entity1031 , clinical presentation, @entity715 location, evolution under treatment and long-term outcome, have been noted. Deficiencies in antithrombine, protein C, protein S, the @entity5337 and the @entity14553 prothrombin-gene mutation, the presence of @entity4555 , of anticardiolipin antibodies as well as a hyperhomocysteinaemia have been searched, either at the initial presentation, or a posteriori. RESULTS: Fourty-one percent of @entity1 had a coagulation abnormality. The prevalence of the different abnormalities was: @entity74 in @entity1129 7.4%, in PC 8%, in PS 12.5%, @entity5337 mutation 12%, @entity14553 prothrombin-gene mutation 12%. Two @entity1 had combined defects: @entity1129 and @entity15310 in one, F V Leiden and F II @entity14553 mutations in one. e of the @entity1 had @entity4555 . Three @entity1 had a significant rate of anticardiolipin antibodies. Five @entity1 out of eight displayed a moderate hyperhomocysteinaemia. Nothing (past history, age, predisposing factors) distinguished those @entity1 bearing a @entity3459 from the others. The venous thromboembolic relapse rate of 15 % (4/27 @entity1 ). Three of them had an inherited @entity854 . CONCLUSION: We recommend an investigation of the haemostasis after every @entity49 .
