Autologus platelet gel for the management of persistent XXXX after lung resection.

@entity1143 @entity1 @entity3509 @entity5641 @entity3669 @entity292 @entity86 @entity12374 @entity456
@entity86 ( @entity292 ) associated with @entity1143 ( @entity1143 ) is a serious complication and a therapeutic challenge in thoracic surgery. The purpose of this study was to assess the efficacy of the use of the autologous platelet gel for the treatment of @entity292 and @entity1143 . We treated a @entity1 with post lung resection persistent @entity292 using a autologous platelet gel, a cellular compose produces at the Division of Immunohaematoligy and Trasfusion. The platelet gel- @entity3669 (Platelet-Rich Plasma) is a biological material made of autologous platelets, extracted from a small amount of the @entity1 's blood, centrifuged at 1100 g for 9 min. The @entity3669 obtained was activated by addition of autologous thrombin and @entity12374 to form a matrix of fibrin (PRFM) thick. The @entity1 presented important air leak after middle lobe wedge resection for solitary lung lesion with standard open decortication for important @entity456 post @entity5641 . On postoperative day XIII the @entity1 developed a thoracic @entity3509 and consequently underwent a antibiotic pleural irrigation through the chest drainage based on the microbiological analysis of the pleural fluid. After a week we obtained the resolution of the @entity3509 but a residual space remained and air leak persisted. We treated the @entity1 with autologous platelet gel. We administer 7.5 mL of the autologous platelet gel across the chest drainage ever 72 hours for 3 times. After the third application we had the closure of the cavity and the cessation of air leak. Autologous platelet gel is easy to use, safe and inexpensive. It can be considered a valid therapeutic option in selected @entity1 with @entity292 and a lung partial re-expansion. The product consist of a significant amount of cellular components with healing anti-inflammatory an proregenerative properities that permit the body to heal tissue wounds faster and more efficiently. A sterile @entity1143 is fundamental conditions for the final success of the procedure.
