Anticoagulation and incidence of late XXXX following the Fontan procedure.

@entity1 @entity5953 @entity64 @entity548 @entity117 @entity1031 @entity715
@entity1031 events are a well-reported complication following the Fontan procedure, but no previous studies have compared the incidence of @entity1031 events relative to the prophylactic anticoagulation strategy utilized. We examined the time-adjusted incidence of late @entity1031 events relative to chronic anticoagulation strategy. All @entity1 who have undergone Fontan palliation and are followed at our institution were reviewed. All @entity1031 and major @entity548 events were recorded and compared among different subgroups (anticoagulant medication utilized, Fontan variant, and the presence of a residual right-to-left shunt). The incidence of late @entity64 ( @entity64 ) per @entity1 -year was calculated for each subgroup. The records of 132 @entity1 were analyzed (median follow-up, 7.6 years; 1066.5 total @entity1 -years). There were no major @entity548 complications. One @entity1 receiving no anticoagulation therapy developed a symptomatic @entity715 6 months after Fontan. Three @entity1 suffered late @entity64 (range, 3-7 years); 2 were receiving @entity117 , and the other received no anticoagulation therapy. @entity5953 had lateral tunnel Fontan and a residual right-to-left shunt. The overall incidence of late @entity64 was 2.3%, with an event rate of 0.28% per @entity1 -year. Late @entity64 was not related to anticoagulation strategy or time from Fontan procedure but was associated with a residual right-to-left shunt and lateral tunnel-type Fontan palliation (p < 0.001). Regardless of anticoagulation strategy utilized, symptomatic @entity64 is a rare long-term complication following the Fontan procedure.
