XXXX in falciparum malaria--some prospective observations.

@entity1 @entity1087 @entity3964 @entity311 @entity99 @entity221
The present prospective study of slide positive @entity3964 @entity1 revealed a higher (17%) incidence of @entity1087 . This is much higher than reported earlier. Serum transaminases were raised by two to three times the normal value. Histologically the most conspicuous finding was reticulo-endothelial cell proliferation in the liver along with mononuclear cell infiltration. Malarial parasites were not found in the biopsy specimens. Mortality was high especially amongst the late presenters. In areas endemic for @entity311 , awareness of this entity is important. In a @entity1 with @entity221 and @entity1087 with or without altered sensorium, disproportionate hyperbilirubinaemia but with only mild elevation of liver enzymes could help differentiate these cases from @entity99 . The diagnosis can be confirmed by peripheral blood examination, done if required. As the mortality in late presenters is high, early diagnosis in such cases with institution of specific therapy may be life saving.
