[Surgical treatment of post- XXXX : clinical analysis].

@entity1 @entity1188 @entity439
OBJECTIVE: To explore the clinical experiences, efficacies and postoperative left ventricular remodeling changes of surgical ventricular reconstruction in the treatment of post- @entity1188 . METHODS: The investigators reviewed retrospectively the clinical data, operative approaches and follow-up outcomes of consecutive 194 @entity1 with post- @entity1188 , who underwent surgical ventricular reconstruction between January 1997 and December 2009. There were 54 cases in the linear group and 137 cases in the endoventricular patch plasty group. The changes of ventricular remodeling were measured by peri-operative and follow-up echocardiography. RESULTS: All @entity1 underwent surgery with a mean cardiopulmonary bypass duration of (103    35) min and aortic cross clamp duration of (62    26) min. There were 8 per-operative deaths with a mortality rate of 2.2%. Angina pectoris of other cases disappeared and heart function greatly improved. After operation, the ventricular remodeling results showed that in the linear group, there was not significant difference in the changes of ventricular remodeling of post-op 2 weeks, 6 months, 1 year and 5 years versus pre-operation. However, in the endoventricular patch group, the changes of ventricular remodeling of post-op 2 weeks and follow-up 6 months versus pre-operation were significantly reduced (P < 0.05). End-systolic volume (LVESV) reduced from (129    27) ml to (65    8) ml and end-systolic volume index (LVESVI) decreased from (104    14) ml/m(2) to (44    6) ml/m(2) and the subgroup of LVEF < 35% was the most significant in the changes of LVESV and LVESVI. But LVEF improved significantly at post-operation and follow-up (from preoperation 42%    11% to 52%    7% during follow-up). CONCLUSIONS: For @entity1 with @entity1188 , left ventricular reconstruction is quite effective. The choice of operative approaches is determined by the size and range of @entity439 . Both string suture and endoventricular patch plasty technique can yield similarly satisfactory surgical outcomes. After operation, ventricular volume significantly decreases and cardiac function greatly improves.
