Effects of exercise on cognitive and motor function in @entity5815 and XXXX .

@entity1 @entity308 @entity1295 @entity5815
OBJECTIVES: @entity1 with @entity5815 complain of physical and mental @entity1295 that is worsened by exertion. It was predicted that the cognitive and motor responses to vigorous exercise in @entity1 with @entity5815 would differ from those in @entity308 and healthy controls. METHODS: Ten @entity1 with @entity5815 , 10 with @entity308 , and 10 healthy controls completed cognitive and muscle strength testing before and after a treadmill exercise test. Measures of cardiovascular functioning and perceived effort, @entity1295 , and mood were taken during each stage of testing. RESULTS: Depressed @entity1 performed worst on cognitive tests at baseline. During the treadmill test, @entity1 with @entity5815 had higher ratings of perceived effort and @entity1295 than both control groups, whereas @entity1 with @entity308 reported lower mood. After exertion, @entity1 with @entity5815 showed a greater decrease than healthy controls on everyday tests of focused (p=0.02) and sustained (p=0.001) attention, as well as greater deterioration than @entity308 @entity1 on the focused attention task (p=0.03). No between group differences were found in cardiovascular or symptom measures taken during the cognitive testing. CONCLUSIONS: @entity1 with @entity5815 show a specific sensitivity to the effects of exertion on effortful cognitive functioning. This occurs despite subjective and objective evidence of effort allocation in @entity5815 , suggesting that @entity1 have reduced working memory capacity, or a greater demand to monitor cognitive processes, or both. Further insight into the pathophysiology of the core complaints in @entity5815 is likely to be realised by studying the effects of exercise on other aspects of everyday functioning.
