Post-operative oral contraceptive use reduces the risk of XXXX recurrence after laparoscopic excision.

@entity43 @entity1 @entity46
BACKGROUND: The aim of this study was to evaluate the impact of post-operative oral contraceptives (OCs) use on the rate of recurrence after laparoscopic excision of @entity43 . METHODS: In May 2005, we introduced a 'post-operative OC recommendation' for @entity1 treated with laparoscopic excision of @entity46 . That is, at the time of the operation, we provided each @entity1 with information about OC, known and possible benefits and risks and let her decide whether to take OC. A retrospective cohort study included 87 @entity1 who underwent a laparoscopy after May 2005. The @entity46 recurrence rate at 24 months was compared between those who used OC for the entire follow-up period OC (n = 34) and all of the others (n = 53). We also performed logistic regression analysis to identify variables associated with recurrence. A before-after study included another 224 @entity1 who underwent a laparoscopy before May 2005 and compared the recurrence rate before and after introduction of the 'post-operative OC recommendation'. RESULTS: The recurrence rate in those who used OC for the entire period was significantly lower than in the 'others' group (2.9 versus 35.8%, relative risk 0.082, 95% CI 0.012-0.58, P < 0.001). Post-operative OC was determined as an independent variable associated with lower recurrence (OR 0.054, 95% CI 0.007-0.429, P < 0.001). The overall recurrence rate in @entity1 who underwent laparoscopy after the introduction of the 'post-operative OC recommendation' was significantly lower than that in @entity1 who received laparoscopy before the introduction (18.6 versus 33.1%, relative risk 0.56, 95% CI 0.32-0.97, P < 0.05). CONCLUSIONS: Post-operative OC use reduces the risk of @entity43 recurrence after laparoscopic excision. This information will help in appropriate planning of pre- and post-operative management.
