Spinal cord @entity3271 with 1p deletion: report of a relapsing case treated with XXXX .

@entity1 @entity41 @entity5 @entity602 @entity425 @entity158 @entity2903 @entity3271
Primary spinal cord @entity5 is very rare, and in only one @entity1 with @entity602 has a deletion of chromosome 1p/19q been reported. We present the case of an 18-year-old @entity1 , who had one-year lower back @entity158 and one-month lower limb @entity425 . Magnetic resonance images of the spinal cord showed an intramedullary mass from level T8 to T10, which was then radically removed. Histology revealed an @entity3271 . The @entity1 was treated with radiotherapy postoperatively. Eight months after the treatment, follow-up magnetic resonance images disclosed an enhancing intramedullary mass at level T4-T8; recurrence of the @entity5 was therefore diagnosed. Maximum surgical @entity5 was performed, diagnosis of @entity3271 was made, and a chromosome 1p deletion was determined by FISH. After treatment with @entity2903 for six months, the @entity1 had a remarkable improvement of her lower limb symptoms, and complete imaging regression of the @entity41 showed no evidence of recurrence at any other sites. The most recent MRI of brain and spinal cord showed postoperative changes without evidence of @entity5 recurrence of the spine and oligodendrogliomatosis along the cerebral-spinal axis. To our knowledge, this is the first report of a recurrent @entity3271 with 1p deletion occurring in the spinal cord. It is also the first case of the @entity1 with recurrent intramedullary @entity3271 who had a significant clinical improvement and complete imaging remission after subtotal resection then treatment with @entity2903 chemotherapy.
