The place of extensive surgery in locoregional recurrence and limited metastatic disease of XXXX : preliminary results.

@entity1 @entity0 @entity5 @entity3
The aims of this study were first to clearly define two different entities: locoregional recurrences and limited metastatic disease and secondly to evaluate the place of extensive surgery in these two types of recurrence. Material and Methods. Twenty-four @entity1 were followed from June 2004 until May 2014. All @entity1 underwent surgery but for 1 @entity1 this surgery was stopped because the @entity5 was unresectable. Results. The median interval between surgery for the primary @entity5 and the locoregional recurrence or metastatic evolution was 129 months. Eight @entity1 had pure nodal recurrences, 4 had nodal and muscular recurrences, 5 had muscular + skin recurrences, and 8 had metastatic evolution. Currently, all @entity1 are still alive but 2 have liver @entity3 . Disease free survival was measured at 2 years and extrapolated at 5 years and was 92% at these two time points. No difference was observed for young or older @entity1 ; limited metastatic evolution and locoregional recurrence exhibited the same disease free survival. Conclusion. Extensive surgery has a place in locoregional and limited metastatic @entity0 recurrences but this option must absolutely be integrated in the multidisciplinary strategy of therapeutic options and needs to be planned with a curative intent.
