Sexual Receptivity Facilitated by Unesterified @entity53 : Dependence on @entity172 and Progestin Receptors and Priming Dose of XXXX .

@entity172 @entity440 @entity1420 @entity53 @entity27557 @entity4520 @entity1515 @entity35 @entity3927
UNASSIGNED: In some conditions, female sexual behavior in ovariectomized @entity35 can be induced by continuous exposure of @entity53 (E2) alone or by a single injection of a high dose of the long-lasting, esterified @entity4520 (EB). However, there are inconsistencies in the literature on the role of @entity172 during priming or in the facilitation on female sexual behavior in EB-primed @entity35 , as well as the cellular mechanisms involved. Either subcutaneous (sc) or intracerebral (icv) administration of some doses of free unesterified E2, induced @entity1515 in EB-primed @entity35 . Either sc or icv injection of E2, immediately prior to testing, induced high levels of sexual receptivity when the female @entity35 were primed with an EB sc injection of 2  g EB. The roles of @entity1420 receptor (PR) and @entity172 receptor on @entity1515 induced by sc or icv administration of E2 were explored. @entity440 or @entity3927 administrated sc or icv; each reduced @entity1515 induced by E2. Similarly, antisense oligonucleotides directed at @entity27557 or total PR (PR-A + @entity27557 ) administrated icv immediately before EB injection inhibited @entity1515 induced by daily injections of EB. These results suggest that @entity1515 facilitated by free E2 is dependent on priming dose of EB. Furthermore both ERs and PRs are involved in this action of E2. (PsycINFO Database Record
