Sex-related differences in outcome after vascular interventions for XXXX .

@entity1 @entity204 @entity676 @entity63
OBJECTIVE: The purpose of this study was to investigate sex-related differences in outcome, defined as amputation rate and survival in @entity1 treated for @entity63 . MATERIAL AND METHOD: Age, sex, and type of procedure for all @entity1 undergoing vascular interventions for @entity63 in Stockholm, Sweden, from 1970 to 1994, were obtained from the National Board of Health and Welfare. All @entity1 who underwent amputation after treatment were analyzed separately. Data on deceased @entity1 were extracted from the cause-of- @entity204 register. RESULTS: @entity1 had lower survival rates than @entity1 at 30 days @entity676 years after operation (89% vs 92%, 75% vs 80%, and 50% vs 55%; P <.001). In the multivariate analysis of risk factors for @entity204 during the whole study period, increasing age, calendar year (1980 to 1989), and male sex were significant risk factors (P <.001). The percentage of @entity1 who underwent amputation after treatment was comparable with the percentage of @entity1 who underwent amputation (11.4% vs 10.2%, P =.075). The multivariate analysis identified increased age and calendar year (1985 to 1994) as important risk factors for amputation (P <.001). Female sex was not found to increase the risk for amputation. @entity1 who underwent amputation were older than @entity1 with intact limbs (73 vs 68 years, P <.001). The highest percentage of @entity1 who underwent amputation was found among those treated with femorodistal bypass (20%, P =.001). CONCLUSIONS: Female sex is not an important risk factor for poor outcome after treatment for @entity63 , when their increased age has been accounted for. These results imply that we should continue to consider age and type of procedure when estimating outcome, and @entity1 should not be refused an intervention on a sex-related basis. We should possibly be more selective toward @entity1 considering their higher mortality rates.
