Prospective evaluation of complications of the usage of buffering XXXX for secondary intention healing.

@entity1 @entity2318 @entity3303 @entity158 @entity282
Abstract Background: Circular excision by secondary-intention healing is useful for small skin defects (diameter <10 mm). But the injection @entity158 as the local anesthesia is administered one of the @entity1 ' biggest concerns. Buffered @entity3303 can effectively relieve the injection @entity158 , but it might increase the potential complications. This study examined the effect of buffered @entity3303 on wound healing. METHODS: @entity1 undergoing circular excision by secondary-intention healing were divided into 2 groups and were administered buffered or unbuffered @entity3303 as the local anesthesia. Comparative parameters included injection @entity158 , @entity282 , complication rate, @entity2318 at 6 months. Statistical differences between the 2 agents were assessed. RESULTS: The @entity1 in the buffered group experienced 0.9 fewer scaled injection @entity158 units than did the @entity1 in the unbuffered group (p = 0.009). Complication rates and scar appearance did not show any statistical difference between the 2 groups. CONCLUSION: Buffered @entity3303 is useful to relieve the injection @entity158 during the secondary-intention healing, and it is safe to use if it is applied properly.
