XXXX in pregnant population, which empirical antimicrobial agent should be specified in each of the three trimesters?

@entity1 @entity6616 @entity5645 @entity8912 @entity4005 @entity293 @entity526
OBJECTIVE: We aimed to investigate the bacterial profile and the adequacy of antimicrobial treatment in pregnant @entity1 with @entity293 . MATERIAL AND METHODS: This retrospective observational study was conducted with 753 pregnant @entity1 who needed hospitalization because of UTI in each of the three trimesters. Midstream urine culture and antimicrobial susceptibility tests were evaluated. RESULTS: @entity526 was the most frequently isolated bacterial agent (82.2%), followed by @entity4005 @entity5645 . (11.2%). In each of the three trimesters, @entity526 remained the most frequently isolated bacterium (86%, 82.2%, 79.5%, respectively), followed by @entity4005 @entity5645 . (9%, 11.6%, 12.2%, respectively). Enterococcus @entity5645 . were isolated as a third microbial agent, with 43 @entity1 (5.7%) in the three trimesters. The bacteria were found to be highly sensitive to @entity8912 , with 98-99% sensitivity for @entity526 and 88-89% for @entity4005 @entity5645 . and for Enterococcus @entity5645 . 93-100% @entity6616 sensitivity for each of the three trimesters. CONCLUSIONS: We demonstrated that @entity526 and @entity4005 @entity5645 . are the most common bacterial agents isolated from urine culture of pregnant @entity1 with UTI in each of the three trimesters. We consider @entity8912 to be the most adequate first-line treatment regimen due to high sensitivity to the drug, ease of use and safety for use in pregnancy
