XXXX in Germany.

@entity1 @entity2735 @entity5 @entity189 @entity281 @entity395
OBJECTIVE: Vulvar and @entity5 are @entity395 with an incidence rate that increases with age. At present, epidemiological data are rather scarce. This review article provides an epidemiologic overview of these diseases, focussing on recent German data. METHODS: This review article summarizes the information currently available in order to offer an epidemiologic overview. RESULTS: The statistic incidence of @entity189 has been calculated between 2 and 7 cases per 100,000 @entity1 , and that of @entity189 0.6-1.0 cases per 100,000 @entity1 . These incidence rates, especially concerning @entity2735 , have increased heavily since the 1970s. The mean age of @entity5 affection is 72 years, and 74 years for @entity189 . In the case of @entity1 below the age of 50, @entity5 tends to be HPV-associated which implies a coincidence of about 20% for cervical and @entity5 . Various pathological mechanisms are the cause for @entity1 above the age of 50. CONCLUSIONS: Due to a change in sexual behavior and an increased rate of @entity281 among younger @entity1 , increased incidence of both diseases has to be expected. The age-standardized mortality rate of @entity189 in Europe is stated at 0.7/100,000 @entity1 , and that of @entity189 at 0.4/100.000 @entity1 . To what extent the HPV-vaccination affects incidence and mortality rates is continually being observed.
