Comparison of the effects of streptokinase and heparin on the early rate of resolution of major XXXX .

@entity1 @entity556 @entity5122 @entity120 @entity1151
The extent of early resolution of major @entity1151 observed in 10 @entity1 after 24 hours of treatment with heparin was compared with that seen in 17 @entity1 after 24 hours of treatment with streptokinase. The @entity1 in the streptokinase group also received a loading dose of heparin and were treated with heparin by continuous infusion when their @entity556 time returned to normal levels. All had @entity120 . @entity1151 was classified as acute in the 10 @entity1 in the heparin group. Seven of these @entity1 showed no angiographic change, two showed slight improvement and one showed @entity5122 . There was a moderate and statistically insignificant fall in mean pulmonary arterial pressure and total pulmonary resistance. Fourteen of the 17 @entity1 who were studied before and after streptokinase were classified as acute and three as subacute progressive major @entity1151 . Eight showed marked angiographic improvement, four moderate and two slight angiographic improvement. There was a moderate and statistically significant fall in the mean pulmonary arterial pressure and pulmonary vascular resistance. In addition, all seven @entity1 in whom no angiographic improvement occurred during heparin therapy showed moderate or marked angiographic improvement after a further 24 hours of treatment with streptokinase. The results strongly suggest that streptokinase therapy accelerates thrombolysis in @entity1 with acute major @entity1151 .
