[Surgical treatment and prognosis in XXXX with squamous cell carcinoma of @entity1514 esophagus].

@entity1 @entity5 @entity1514 @entity1721 @entity3
OBJECTIVE: To analyze the prognostic factors of @entity1721 (ESCC) after esophagectomy. METHODS: The clinicopathologic data of 716 @entity1 with @entity1514 ESCC from January 1990 to December 1998 were analyzed retrospectively. There were 538 male and 178 female @entity1 aged from 24 to 78 years old with a median of 57 years old. Cumulative survival rate was analyzed by the Kaplan-Meier method and compared by the Log-rank test. COX regression model was used for multivariate prognostic analysis. RESULTS: The overall 1-, 3-, 5- and 10-year survival rates were 82.9%, 44.3%, 34.2% and 25.7% respectively. The 5-year survival rates was 80.0%, 51.2%, 19.7% and 13.3% for stage I, stage IIA, stage IIB and stage III respectively. Of the 716 @entity1 , 151 (21.1%) @entity1 recurred, including 48 (84.2%) of stage IIA recurrence, 22 (91.7%) of stage IIB recurrence and 63 (90.0%) of stage III recurrence occurred within 3 years postoperatively. Univariate analysis revealed that the factors impacting the prognosis were gender, depth of invasion, lymph node @entity3 , pathologic stage, number of lymph node metastatic field, differentiation, surgical margin and @entity5 relapse. Multivariate analysis showed that depth of invasion, lymph node @entity3 , pathologic stage and @entity5 relapse were independently associated to poor prognosis. CONCLUSIONS: Depth of invasion, lymph node @entity3 , pathologic stage and @entity5 relapse are the independent factors of ESCC. Surgery is still the primary treatment for @entity5 ; but it is suggested to adopt surgical treatment as primary modality combined with other therapies for @entity5 .
