Effect of prone positioning in mild to moderate XXXX .

@entity1 @entity1723 @entity27
BACKGROUND: Sleeping in prone position could be effective in the management of @entity27 ( @entity27 ) syndrome by reducing the gravity effect on the upper airway and hence collapsibility. Effect of @entity1723 ( @entity1723 ) treatment was investigated in mild to moderate @entity27 . @entity1 AND METHODS: Twenty-nine mild to moderate @entity27 @entity1 (17 males, 12 females) who gave informed consent were tested with polysomnography at diagnostic and @entity1723 nights. @entity1723 device consisted of a pillow mounted on a table with a hole in the middle keeping the neck 180   extended in prone position. Mean        SD of age and AHI were 48.4        10.6 and 15.5        6.2, respectively. @entity1 did not have abdominal and/or truncalobesity, or any condition that could interfere with prone sleeping. RESULTS: AHI (mean difference: @entity1723 treatment   -   diagnostic night: -5.2/h, 95% confidence interval [CI]: -0.1/h to -10.3/h, p   =   0.04) and sleep oxygen saturation below 90% (mean difference: -1.80%, 95% CI: -0.22% to -3.37%, p   =   0.02) and sleep efficiency (81.0        21.2% and 88.1        7.1 %, respectively, p   =   0.02) were significantly lower in @entity1723 than diagnostic night. Response to @entity1723 treatment defined as AHI <5/h in the @entity1723 night was observed in 15 (51.7%) @entity1 , with a better rate in female than male @entity1 (9/12 vs. 6/17, respectively, p   =   0.03). CONCLUSIONS: To our knowledge, this is the first study to examine the effect of prone positioning in the treatment of mild to moderate @entity27 . Application of @entity1723 with a more comfortable design in a randomized clinical trial is required to investigate its long term effect in the treatment of mild to moderate @entity27 .
