Outcomes of @entity726 valve implantation in advanced primary XXXX with previous surgical failure.

@entity1 @entity548 @entity1713 @entity726 @entity10064 @entity3225
PURPOSE: The purpose of this study was to evaluate the intermediate surgical results of @entity726 valve (AGV) implantation in @entity1 less than 7 years of age, with advanced primary @entity10064 who have failed previous surgeries. @entity1 AND METHODS: Consecutive @entity1 with advanced primary @entity10064 that failed previous operations and had undergone subsequent AGV implantation were evaluated retrospectively. Surgical success was defined as 1) intraocular pressure (IOP) >= 6 and  <=21 mmHg; 2) IOP reduction of at least 30% relative to preoperative values; and 3) without the need for additional surgical intervention for IOP control, loss of light perception, or serious complications. RESULTS: Fourteen eyes of eleven @entity1 were studied. Preoperatively, the average axial length was 27.71  1.52 (25.56-30.80) mm, corneal diameter was 14.71  1.07 (13.0-16.0) mm, cup-to-disc ratio was 0.95  0.04 (0.9-1.0), and IOP was 39.5  5.7 (30-55) mmHg. The mean follow-up time was 18.29  10.96 (5-44, median 18) months. There were significant reductions in IOPs and the number of @entity726 medications (P<0.001) postoperatively. The IOPs after operation were 11.3  3.4, 13.6  5.1, 16.3  2.7, and 16.1  2.6 mmHg at 1 month, 6 months, 12 months, and 18 months, respectively. Kaplan-Meier estimates of the cumulative probability of valve success were 85.7%, 71.4%, and 71.4% at 6, 12, and 18 months, respectively. Severe surgical complications, including erosion of tube, @entity3225 , @entity1713 , @entity1713 , and delayed @entity548 , occurred in 28.6% cases. CONCLUSION: AGV implantation remains a viable option for @entity1 with advanced primary @entity10064 unresponsive to previous surgical intervention, despite a relatively high incidence of severe surgical complications.
