XXXX as sole anesthetic for open liver biopsy.

@entity1 @entity73253 @entity2003 @entity648 @entity409 @entity3652
We evaluated the use of @entity3652 as sole anesthetic agent for open liver biopsy, with particular reference to its effect on liver function and hepatotoxicity and its effect on cardiovascular stability and respiration. From 386 @entity1 who underwent liver biopsy at Jordan University Hospital, 12 had open liver biopsy because of contra-indications for closed needle biopsy. The surgical procedure consisted of a small right paramedian incision allowing inspection of the liver surface and a wedge and needle biopsy. @entity73253 was used in a dose of 2 mg/kg I.V. with supplemental doses as necessary. No significant fluctuations in cardio-respiratory vital signs were observed. @entity2003 and respiratory tagging movements necessitated addition of a muscle relaxant and artificial ventilation in three @entity1 . Six @entity1 reported dreams, two of which were described as nightmares. There was no liver function decompensation, or significant @entity648 or transaminase elevations in the week following the biopsy. @entity3652 is a safe anesthetic to use for open liver biopsy in @entity1 with underlying @entity409 , although poor muscle relaxation and nightmares may be significant side effects.
