Endoluminal cryotherapy in the management of endobronchial XXXX of extrapulmonary origin.

@entity5 @entity1 @entity3
BACKGROUND: Endobronchial @entity3 from extrapulmonary @entity5 are rare and often cause significant symptoms particularly when they present within the main bronchial tree. Cryotherapy has been shown to be effective in the treatment of primary @entity5 of the endobronchial tree. This is the first detailed analysis of the application of cryotherapy to endobronchial @entity3 of extrapulmonary origin. This study assessed the role of endobronchial cryotherapy in the management of these @entity1 , including control of symptoms and improvement in endobronchial patency. METHODS: The details of 35 @entity1 treated over a 17-year period were reviewed. @entity1 ' ages ranged from 22 to 80 years. The @entity5 were mainly colorectal and renal. RESULTS: There were no perioperative or in- @entity1 deaths. Endobronchial cryotherapy was carried out as a day-case procedure in over 80% of cases. Of the 35 @entity1 , 30 (85%) reported a significant improvement in their main presenting symptom. In over half the @entity1 , endoluminal patency was increased by >= 50% following 1 treatment of cryotherapy. Survival ranged from 10 days to 4 years 8 months, with a median survival of 34 weeks. One-year survival was 37.5%. CONCLUSIONS: Endoluminal cryotherapy gives rapid resolution of symptoms and can be carried out as a day-case procedure in the vast majority of @entity1 . We recommend that cryotherapy should be considered as a first-line palliation in @entity1 with symptomatic @entity3 to the endobronchial tree.
