Influence of the Pre-Operative Neurological Status on Survival after the Surgical Treatment of Symptomatic Spinal Metastases with XXXX .

@entity1 @entity5 @entity16 @entity532 @entity1745
STUDY DESIGN: Consecutive case-series OBJECTIVE.: The main purpose of this study was to analyse relationship between the preoperative @entity16 and subsequent survival of @entity1 undergoing surgical treatment for symptomatic spinal metastases. SUMMARY OF BACKGROUND DATA: The survival of @entity5 @entity1 has increased over recent years with improvements in oncologic therapy. As many as 70% of @entity5 @entity1 develop spinal metastases and approximately 10% of all @entity5 @entity1 are treated for metastatic @entity1745 . METHODS: We retrospectively analysed 166 @entity1 who underwent surgery for symptomatic spinal metastases in our department between 2005 and 2012. The evaluated factors were age, primary @entity5 (slow, moderate, rapid growing), spinal location (cervical, thoracic, lumbar and sacral), operation type (posterior decompression, anterior or posterior instrumented procedure and radical combined instrumented surgery), pre-operative evaluation using revised Tokuhashi scoring system (below 9, 9-11 and 12-15), pre- and post-operative @entity16 according Frankel score (A-C and D-E), and the site of the main @entity1745 (anterior, posterior or combined). @entity532 and recurrence rate was also monitored. RESULTS: The mean age of the @entity1 was 62  12 years. The median survival time after surgery was 16.0 months. Pre-operative @entity16 influenced survival time significantly; the median survival was 5.1 months in Frankel A-C and 28.2 months in Frankel D-E. (p<0.001). Improvement on the Frankel scale did not influence the survival time (p=0.131). When the @entity1 ' age was below 65 years this related to a significantly longer survival time (p=0.046). Tokuhashi score predicted @entity1 [Combining Acute Accent]s survival independently (p<0.001). The other factors had no statistical significance. CONCLUSIONS: The most important factors influencing post-operative survival time of these @entity1 with symptomatic spinal metastases was pre-operative @entity16 and Tokuhashi scoring system, which together represents a useful tool for planning the extent of surgical treatment. LEVEL OF EVIDENCE: 4.
