Hepatic arterial chemoembolization for metastatic XXXX .

@entity632 @entity1 @entity14380 @entity712 @entity12983 @entity5 @entity298 @entity409 @entity1416 @entity177 @entity887 @entity4831 @entity4303 @entity3 @entity7581 @entity3990
PURPOSE OF THE STUDY: To evaluate the effectiveness of chemoembolization of the liver with @entity632 and @entity3990 emulsified in ethiodized oil for the treatment of metastatic @entity5 . @entity1 AND METHODS: Twenty @entity1 with hepatic islet cell or @entity4303 @entity3 were treated with selected hepatic @entity1416 consisting of an emulsion of @entity632 and @entity3990 emulsified in @entity4831 followed by Gelfoam powder embolization. Fifteen @entity1 had failed intravenous chemotherapy. Two of the @entity1 with @entity5 had three embolizations over 4 and one 6 years earlier with gelatin sponge only. RESULTS: In 14 @entity1 with hormonally active @entity5 , hormones secretion decreased 90% (range 69-98%) in 10 days with relief of symptoms in all @entity1 . Average @entity5 size decrease was 84%. Average hospital stay was 8 days. Six @entity1 are alive and asymptomatic at 14-33 months postembolization. Fourteen @entity1 have died 2-16 months postembolization. Ten @entity1 died 2-37 months postembolization from progressive @entity409 . One of these @entity1 was 103 months @entity887 and 13 months postchemoembolization. In 8 @entity1 , the pancreas was the primary site: 5 were nonfunctioning @entity14380 , 1 @entity12983 , 1 @entity7581 and 1 @entity4303 . The primary site in 1 @entity1 with @entity4303 was the bronchus, and the primary site was unknown in 1 @entity1 with @entity7581 . The remaining 4 @entity1 died with @entity409 under control from @entity177 , @entity298 , @entity712 and generalized bone @entity3 . The response rate was 95% with median duration of response 8.5 months. The median survival was 24 months. CONCLUSION: Chemoembolization with @entity632 and @entity3990 emulsified in ethiodized oil is less morbid than embolization with particulate matter alone, is more convenient and less costly, and it is less morbid than the effects of systemic chemotherapy. The median survival, duration and response compare favorably with other reported therapies.
