Long-Term Oncologic Outcome of an Initial Series of Laparoscopic Radical Prostatectomy for Clinically Localized XXXX After a Median Follow-up of 10 Years.

@entity1 @entity1803 @entity263 @entity5 @entity1349 @entity1486
INTRODUCTION: When laparoscopic radical prostatectomy (LRP) was introduced as a novel treatment option for @entity263 , it had to compete with the established open techniques. The short- and intermediate-term oncologic and functional outcomes were encouraging and comparable to those with retropubic radical prostatectomy. However, the long-term oncologic safety for LRP has yet to be fully elucidated. We evaluated the long-term oncologic outcomes of an initial series of @entity1 who had undergone LRP. @entity1 AND METHODS: An initial unselected and consecutive series of 100 @entity1 who had undergone LRP for clinically @entity263 from 1999 to 2001 was identified. The pre-, intra-, and postoperative data were collected. Biochemical recurrence (BCR) was defined as a @entity1486 (PSA) value of  >=  0.2 ng/mL. The outcome measures were @entity5 control (CC), BCR-free survival (BCRFS), @entity5 -specific survival (CSS), and @entity1349 ( @entity1349 ). RESULTS: The mean @entity1 age was 64    7 years, and the mean preoperative PSA level was 9.6    8.3 ng/mL. Of the 100 @entity1 , 79 (79%) had stage pT2 and 15 (15%) had stage @entity1803 disease. Positive surgical margins were found in 25 @entity1 (25%; 16.4% for pT2 and 40% for @entity1803 ). The median follow-up time was 126 months (range, 60-176 months). The 5-year CC rate was 82%. The estimated 10-year BCRFS was 83% and 80% for @entity1 with stage pT2 and @entity1803 @entity5 , respectively. The median time to BCR was 52 months (range, 6-144 months). The estimated 10-year CSS and @entity1349 was 98% and 93%, respectively. CONCLUSION: Our long-term follow-up data from an initial unselected @entity1 cohort have indicated that LRP offers excellent long-term oncologic control for @entity1 with @entity263 .
