Associations Between Physical Fitness Indices and Working Memory in XXXX and Age-Matched Controls.

@entity1 @entity410 @entity5 @entity0
BACKGROUND: This study examined the effects of @entity410 , heart rate recovery, and physical activity on working memory in @entity0 survivors and age-matched controls. METHOD: Using a case-control design, 32 @entity1 who had received a @entity0 and completed primary treatment within the past 36-months (11 radiation only; 21 chemotherapy) and 30 age-matched @entity1 with no previous @entity5 diagnosis completed a n-back continuous performance task commonly used as an assessment of working memory. In addition, @entity410 and heart rate recovery were measured during a submaximal graded exercise test and physical activity was measured using 7-days of accelerometer monitoring. RESULTS: Breast @entity5 survivors who had received chemotherapy had poorer heart rate recovery (p   =   .010) and engaged in less physical activity than @entity1 who had received radiation only (p   =   .004) or non- @entity5 controls (p   =   .029). Cancer treatment (radiation; chemotherapy) predicted differences in reaction times on the 1-back working memory task (p   =   .029). However, more rapid heart rate recovery predicted shorter reaction times on the 1-back task in the age-matched control group (p   =   .002). All @entity1 with greater @entity410 displayed greater accuracy independent of disease status on the 1-back task (p   =   .017). No significant group differences in reaction times were observed for 2-back target trials between @entity0 survivors and controls. However, greater total physical activity predicted shorter reaction times in @entity0 survivors (radiation, chemotherapy) on the 2-back task (p   =   .014). In addition, all @entity1 who exhibited more rapid heart rate recovery demonstrated better greater accuracy regardless of disease status (p   =   .013). CONCLUSION: These findings support differences in physical activty participation, heart rate recovery, and 1- and 2-back working memory reaction times between @entity0 survivors and age-matched controls. Greater @entity410 , heart rate recovery, and physical activity were positively associated with better working memory performance across conditions.
