Analysis of Meibum Before and After Intraductal Meibomian Gland Probing in Eyes With XXXX .

@entity1 @entity409 @entity5958 @entity941
PURPOSE: To evaluate whether the amount of meibum and its viscosity change after intraductal meibomian gland probing in @entity1 with @entity409 (o-MGD). METHODS: Six lid margins of 3 @entity1 with refractory o-MGD underwent intraductal meibomian gland probing. Meibum and the clinical outcome were evaluated before the procedure and at a 1-month postoperative visit. Meibum was quantified with a Meibometer, and its viscosity (Shimazaki grade) was assessed simultaneously. The tear film condition was evaluated by lipid layer interferometry ( @entity5958 , Kowa, Nagoya, Japan), and meibomian gland loss was analyzed by noncontact infrared meibography. Lid margin findings, tear break-up time, @entity941 score, and ocular symptoms were also assessed. RESULTS: At the postoperative visits, all cases showed improvements in meibum lipid levels (446-1376, 757-802, and 396-571 meibometer units) and meibum viscosity (grade 3-0, 3-1, and 3-2). Two cases showed an improvement in tear break-up time (2-5 and 0-6 seconds). No morphological changes in the meibomian gland were observed in any cases. CONCLUSIONS: Intraductal meibomian gland probing seems to improve meibomian gland lipid levels, and it may be a good treatment option for cases of o-MGD that are resistant to conventional treatment.
