Risk factors for complications of endoscopic submucosal dissection in XXXX : analysis of 478 lesions.

@entity1 @entity8 @entity101 @entity548 @entity6 @entity75 @entity5 @entity409 @entity1504 @entity741 @entity5052 @entity356
PURPOSE: Endoscopic submucosal dissection (ESD) technique has facilitated en bloc removal of widely spread lesions from the stomach. This retrospective study aimed to determine factors associated with serious complications of ESD. METHODS: Between December 2001 and March 2007, we have performed ESD for 478 lesions in 436 @entity1 . We experienced 39 @entity1 with @entity548 and 17 @entity1 with perforation. Risk factors of @entity1 who received ESD in @entity356 for complications were evaluated, focusing on resected size, location, @entity75 , operation time, and experience of endoscopists. We evaluated the @entity1 ' background characteristics including sex, age, body mass index (kg/m(2)), drug history of anticoagulant, and underlying diseases including @entity1504 , @entity741 , @entity409 , @entity8 , @entity5052 , @entity101 and @entity6 . RESULTS: Multivariate analysis indicated a risk factor for perforation was long operation time. Multivariate analysis indicated a significant risk factor for @entity548 was size of the resected @entity5 . CONCLUSIONS: This study indicated risk factors for serious complications of ESD. Large resected @entity5 size was a risk factor for @entity548 , while long operation time was a risk factor for perforation. Information regarding operation risk factors should be useful for planning strategies for ESD.
