Age >= 80 Years Is Not a Contraindication for Intra-Arterial Therapy after XXXX .

@entity1 @entity64 @entity2653 @entity932 @entity955 @entity385
BACKGROUND: Clinical trials confirmed the safety and efficacy of intra-arterial therapy (IAT) in the management of @entity385 . At a community hospital, we compared outcomes in @entity1 aged >= 80 and @entity1 in the age range 55-79 years receiving IAT following @entity385 . METHODS: Data were retrospectively abstracted for @entity385 @entity1 >= 55 years treated with IAT at an urban comprehensive @entity64 center between 2010 and 2013. Baseline demographics, incidence of symptomatic @entity932 (sICH), in-hospital mortality, discharge modified @entity2653 (mRS) score (favorable  <=2) and improvement in National Institutes of Health Stroke Scale Score (NIHSS; decreased score at discharge) were compared between @entity1 in the age range 55-79 and @entity1 >= 80 years. Data were analyzed using univariate analyses and multivariate logistic regression. RESULTS: IAT was performed in 239 @entity1 with @entity385 ; 63 (26.4%) were >= 80 years. When compared to @entity1 aged 55-79, the elderly @entity1 were more often female and non-smokers, with a history of @entity955 . No differences were observed in those >= 80 years compared to @entity1 in the age range 55-79 years for sICH (10 vs. 5%, p = 0.23), mortality (24 vs. 18%, p = 0.28), favorable discharge mRS score (13 vs. 19%, p = 0.27), or improvement in NIHSS (83 vs. 92%, p = 0.10). The nonsignificant association of age with the outcomes persisted after adjusting for covariates and when analyzing the subset of @entity1 who received IAT only. CONCLUSIONS: These findings suggest that in a cohort not subject to the criteria of a clinical trial, age >= 80 years should not be a contraindication to IAT.
