The attributable cost, length of hospital stay, and mortality of central line-associated XXXX in intensive care departments in Argentina: A prospective, matched analysis.

@entity1 @entity281
BACKGROUND: Limited information is available on the financial impact of central venous catheter-associated @entity281 ( @entity281 ) in Argentina. To calculate the cost of BSIs in the intensive care department (ICU), a 5-year prospective nested case-control study was undertaken at 3 hospitals in Argentina. METHODS: We studied 6 adult ICUs from 3 hospitals. In all, 142 @entity1 with @entity281 and 142 control @entity1 without @entity281 were matched for hospital, type of ICU, year of admission, length of stay, sex, age, and average severity of illness score. @entity1 ' length of stay in the ICU was obtained prospectively on daily rounds. The hospitals' finance departments provided the cost of each ICU day. The hospitals' pharmacies provided the cost of antibiotics prescribed for BSIs. RESULTS: The mean extra length of stay for @entity1 with @entity281 compared with control @entity1 was 11.9 days, the mean extra antibiotic defined daily dose was 22.6, the mean extra antibiotic cost was  1913, the mean extra cost was  4888.42, and the excess mortality was 24.6%. CONCLUSIONS: In this study, @entity1 with central venous catheter-associated @entity281 experienced significant prolongation of hospitalization, increased use of health care costs, and a higher attributable mortality. These findings support the need to implement preventative interventions for @entity1 hospitalized with central venous catheters in Argentina.
