De novo XXXX in renal allografts in @entity1 .

@entity1 @entity644 @entity8 @entity1985 @entity631
The incidence of de novo @entity631 ( @entity631 ) in transplanted kidneys is around 1 to 2%. In our series, of the 310 grafts that were examined by immunofluorescence microscopy (IF), 29 (9.3%) showed subepithelial IgG deposits, a pattern consistent with the diagnosis of @entity631 . Transplant biopsy had been performed because of the occurrence of @entity644 in 8 @entity1 (pts), for suspected rejection in 16 and systematically in the remaining 9 who had no @entity644 and a normal renal function. In all cases the lesions were identified by IF and were confirmed by electron microscopy (EM) in 14 pts. Granular deposits of IgG were diffuse in 22 cases and segmental in 7. Sequential specimens were available in 17 pts and showed the persistence or the increase of the IgG deposits in all @entity1 but one in whom they had disappeared. Age at transplantation (Tx) ranged from 2 years 3 months to 16 years. Grafts were from cadaveric donors in 27 pts and from living related donors in 2 pts. In none of the recipients was @entity631 the @entity8 of the native kidneys. With a follow-up of 18 to 74 months, 6 pts never developed a @entity644 . In the remaining 23, @entity644 developed 1 to 70 months after Tx, associated with a @entity1985 ( @entity1985 ) in 6 pts.(ABSTRACT TRUNCATED AT 250 WORDS)
