The efficacy of hyperbaric XXXX therapy in the treatment of medically @entity8650 after penile brachytherapy.

@entity1 @entity1095 @entity137 @entity101 @entity6 @entity39 @entity75 @entity5 @entity26 @entity8650 @entity957
PURPOSE: Soft tissue @entity39 is reported in up to 26% of @entity1 undergoing radiotherapy for @entity5 . Management options include local irrigation, wound debridement, antibiotics, anti-inflammatory medication, and analgesics. @entity75 may be treated with partial penectomy. Hyperbaric @entity26 therapy (HBO) has a well-defined role in the treatment of late radiation @entity137 . We present experience with HBO for medically @entity8650 after penile brachytherapy. METHODS AND MATERIALS: From November 2001 to January 2009, 7 @entity1 of 43 treated with penile brachytherapy for @entity957 developed @entity8650 and were treated with HBO. All had received a prescribed dose of 60 Gy through interstitial brachytherapy using Paris system guidelines. All had failed conservative medical therapies for soft tissue @entity39 . RESULTS: Median age was 55 years (range, 35-72 years). Comorbidities potentially effecting wound healing included @entity101 (2), current smokers (5), former smoker (1) but no @entity6 , or @entity1095 . Median time between completion of brachytherapy and appearance of soft tissue @entity39 was 13 months (range, 9-24 months) and the median interval before starting HBO was 7.5 months (range, 3-13 months). The median number of "dives" per HBO course was 40 (30-53). All 7 experienced an excellent response with healing of the @entity39 and resolution of symptoms, although 3 required an additional course, 2 for consolidation of healing, and 1 for a relapse 4 months later. No @entity1 was submitted to penectomy. CONCLUSIONS: HBO should be considered as a treatment option in @entity1 with @entity8650 of the penis after brachytherapy.
