Thorotrast-induced XXXX : CT identification.

@entity1 @entity5 @entity5426 @entity201 @entity157 @entity99
Despite discontinuation of its use in the 1950s, the consequences of Thorotrast usage continue to be recognized. In a review of plain film and CT findings of 20 cases of Thorotrast exposure, 15 of 17 @entity1 demonstrated Thorotrast accumulation in the liver and spleen on plain films. Typically, this appeared as regions of trabeculated increased density within the liver. The spleen was of normal or decreased size and often demonstrated a finely punctate pattern of opacification. Only two @entity5 could be suggested on plain film alone: one hepatic and one splenic. Five @entity1 with @entity99 underwent CT examinations: three with @entity201 , one with @entity5426 , and one with @entity157 . No specific criteria could be established to distinguish among these lesions, as each @entity5 appeared as relatively low-density mass(es). Two cases of @entity5426 appeared as low-density filling defect(s) in the otherwise opaque spleen, one case primary and the other metastatic from the liver. CT was superior to plain radiography in detecting and characterizing Thorotrast distribution and any superimposed @entity5 . In addition to periodic liver function tests, screening CT of @entity1 exposed to Thorotrast might detect @entity99 at an operable stage.
