Do lung recruitment maneuvers decrease XXXX ?

@entity1 @entity2507 @entity356 @entity647
OBJECTIVE: To evaluate effects of lung recruitment maneuvers on @entity356 , systemic circulation, and lung mechanics in @entity1 with @entity647 . DESIGN: Prospective observational clinical study. SETTING. General intensive care unit of university hospital. @entity1 AND @entity1 : Fourteen @entity1 with @entity647 (ten in the main study group and four in a validation group). INTERVENTIONS. Three 2-min-long recruitment maneuvers (RM) with transient increases in mean airway pressure to 35 cm @entity2507 (RM1 and RM2) and 44 cm @entity2507 (RM3). MEASUREMENTS AND RESULTS: Measurements of systemic hemodynamics, @entity356 (laser Doppler flowmetry), and lung mechanics were performed immediately before, at the end of, and 3 min after each RM. Cardiac index decreased during all RMs while mean arterial pressure decreased only during RM3. Gastric mucosal perfusion was not significantly changed during any of the RMs. When comparing values obtained before the first RM with values after the third RM there was a significant decrease in cardiac index ( P=0.043) and a non-significant ( P=0.051) decrease in @entity356 . There were no significant changes in systemic oxygenation or lung mechanics after three RMs, even though four @entity1 showed marked transient increases in systemic oxygenation during RMs. CONCLUSIONS: In this study of ten @entity1 there were no significant changes in @entity356 during lung recruitment maneuvers. There was, however, a trend towards gradual decreases in @entity356 .
