The role of diffusion-weighted imaging and the apparent diffusion coefficient (ADC) values for XXXX .

@entity1 @entity3079 @entity0 @entity5 @entity189 @entity513
OBJECTIVE: We wanted to evaluate the role of diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) for detecting @entity0 , as compared with the T1- and T2-weighted images. MATERIALS AND METHODS: Forty-one female @entity1 underwent breast MRI, and this included the T1-, T2-, DWI and dynamic contrast-enhanced images. Sixty-five enhancing lesions were detected on the dynamic contrast-enhanced images and we used this as a reference image for detecting @entity5 . Fifty-six breast lesions were detected on DWI and the histological diagnoses were as follows: 43 invasive @entity513 , one @entity189 , one mixed @entity3079 , seven @entity513 in situ (DCIS), and four @entity5 . First, we compared the detectability of breast lesions on DWI with that of the T1- and T2-weighted images. We then compared the ADCs of the malignant and benign breast lesions to the ADCs of the normal fibroglandular tissue. RESULTS: Fifty-six lesions were detected via DWI (detectability of 86.2%). The detectabilities of breast lesions on the T1- and T2-weighted imaging were 61.5% (40/65) and 75.4% (49/65), respectively. The mean ADCs of the @entity513 (0.89+/-0.18 x 10(-3)mm(2)/second) and DCIS (1.17+/-0.18 x 10(-3)mm(2)/ second) are significantly lower than those of the benign lesions (1.41+/-0.56 x 10(-3)mm(2)/second) and the normal fibroglandular tissue (1.51+/-0.29 x 10(-3)mm(2)/ second). CONCLUSION: DWI has a high sensitivity for detecting @entity0 , and especially for detecting @entity0 . DWI was an effective imaging technique for detecting breast lesions, as compared to using the T1- and T2-weighted images.
