Palliative Reconstruction for the Management of Incurable XXXX .

@entity1 @entity135 @entity5 @entity957 @entity260
UNASSIGNED: Background   Surgical management of @entity135 is resource intensive and physiologically demanding. In @entity1 with incurable disease, although the indications for surgery are not well defined, palliative benefit can be significant. The goal of this investigation was to compare outcomes of @entity1 who underwent resection and reconstruction of @entity135 with curative intent with those who underwent similar procedures with palliative intent. Methods   A retrospective review of @entity1 who underwent reconstruction for @entity135 between 2008 and 2014 was conducted. @entity1 were divided into curative and palliative groups. Outcomes assessed included @entity260 and survival. Results   A total of 147 @entity1 who underwent 156 operations met inclusion criteria (27 palliative and 129 curative). In both cohorts, the most common histology was @entity957 ( @entity957 ) and the most common primary @entity5 site was the oral cavity. There was no significant difference between the cohorts in the rates of systemic and reconstructive complications, postoperative hospital length of stay, 30-day mortality, and flap survival. Overall survival in palliative @entity1 was significantly shorter compared with curative @entity1 (median OS, 6.2 months vs. 56.1 months, respectively; p   <   0.0001). Among @entity1 undergoing palliative surgery, @entity1 without carotid involvement and those with non- @entity957 were significantly more likely to have longer survival. Conclusion   Surgical resection with reconstruction is possible in head and neck oncologic @entity1 undergoing palliative treatment. Palliative @entity1 have similar short-term outcomes when compared with @entity1 undergoing resection for curative intent. Quality-of-life and economic implications of these approaches deserve closer scrutiny.
