Improvement of grasping after @entity1957 in C6-C7 XXXX : A kinematic and MEG pilot study.

@entity1 @entity1688 @entity3140 @entity1957 @entity2483
PURPOSE: Grasp recovery after @entity2483 ( @entity2483 ) requires learning "tenodesis grasp" whereby active wrist extension elicits passive thumb-to-forefinger and finger-to-palm flexion. Evidence that @entity1957 ( @entity1957 ) promotes @entity3140 after @entity1688 is growing, but whether @entity1957 potentiates grasp recovery in C6-C7- @entity2483 individuals who have successfully learned the "tenodesis grasp" remains unknown. METHODS: Six chronic stable C6-C7- @entity2483 inpatients and six healthy control @entity1 were included. C6-C7- @entity2483 @entity1 imagined grasping movements and controls visualized geometric forms for 45 minutes, three times a week for five weeks. Three separate measures taken over a five week period before the intervention formed the baseline. Intervention effects were assessed immediately after the intervention and eight weeks later. Each testing session consisted of kinematic recordings during reach-to-grasp and magnetoencephalographic (MEG) recordings during wrist extension. RESULTS: During baseline, kinematic wrist extension angle during "tenodesis grasp" and MEG contralateral sensorimotor cortex (cSMC) activity during wrist extension were stable. Moreover, @entity2483 @entity1 exhibited a greater number of voxels within cSMC than controls. After @entity1957 sessions, wrist extension angle increased during "tenodesis grasp" and the number of voxels within cSMC during wrist extension decreased and became similar to controls. CONCLUSION: These findings provide further support for the use of @entity1957 to reinforce a compensatory grasping movement (tenodesis) and induce brain plasticity.
