Visceral Adipose Tissue in XXXX with @entity30 Correlates with Disease Activity, Inflammatory Markers, and Outcome.

@entity1 @entity650 @entity30 @entity1386
BACKGROUND: @entity1386 ( @entity1386 ) could affect @entity30 ( @entity30 ); however, no prospective clinical studies have explored the issue. METHODS: We measured @entity1386 with magnetic resonance imaging and total fat mass (FM) with air-displacement plethysmography in 31 @entity1 with @entity30 in remission and 19 matched control @entity1 . We assessed the @entity1386 /FM ratio as index of @entity1386 accumulation, measured cytokines, and monitored clinical features (duration of remission, disease behavior, and outcome) in @entity1 with @entity30 retrospectively and prospectively. We also tested whether ultrasound could provide a surrogate marker of @entity1386 in @entity1 with @entity30 . RESULTS: @entity1 with @entity30 had higher percentage of FM (37    10% versus 31    10%, P = 0.03), @entity1386 (1885    1403 mL versus 941    988 mL, P = 0.02), and @entity1386 /FM ratio (65    24 mL/kg versus 37    25 mL/kg, P = 0.004) than control @entity1 . In @entity1 with @entity30 , @entity1386 /FM ratio was associated with leptin (P = 0.009) and @entity650 (P = 0.032) concentrations, and higher in short-term than in long-term remission (72.6    27.1 mL/kg versus 54.8    16.1 mL/kg, P = 0.079). @entity1 with @entity30 with stricturing/fistulizing disease had a higher @entity1386 /FM ratio than @entity1 with nonstricturing/nonfistulizing behavior (79    0.15 mL/kg versus 63    28 mL/kg, P = 0.067). A higher baseline @entity1386 /FM ratio was associated with an increased disease activity at follow-up (P = 0.029). The ultrasound-determined thickness between the abdominal wall and the aorta was strongly associated with @entity1386 as measured by magnetic resonance imaging (P < 0.001). CONCLUSIONS: @entity1386 accumulation could be a prospective risk factor for increased disease activity in @entity30 .
