Limb salvage in severe XXXX .

@entity281 @entity551 @entity6 @entity39
BACKGROUND: The purpose of our study was to determine the efficacy of a management algorithm that includes @entity551 ( @entity551 ) in @entity6 with limb-threatening @entity281 . MATERIALS AND METHODS: Forty-five @entity6 were treated with @entity551 between 2006 and 2008. After emergent abscess evacuation, early vascular intervention was performed if necessary. Debridement, with or without partial foot amputation, was followed by @entity551 . Wound progress was measured using a digital scanner. A limb was considered salvaged if complete healing was achieved without any or with minor amputation through or below the ankle. The mean followup after complete wound healing was 17 (range, 6 to 35) months. RESULTS: Thirty-two cases (71%) were infected with two or more organisms. Negative pressure wound therapy was applied for 26.2  14.3 days. The median time to achieve more than 75% wound area granulation was 23 (range, 4 to 55) days and 104 (range, 38 to 255) days to complete wound healing. Successful limb salvage was achieved in 44 cases (98%); 14 (31%) without any amputation and 30 (67%) with partial foot amputations. Total number of operations per limb was 2.4  1.3. One case of repeated @entity281 and @entity39 was managed with a transtibial amputation. There were no complications associated with @entity551 . CONCLUSION: This study provides the outcome of a management algorithm which includes @entity551 in salvaging severely infected @entity6 . With emergent evacuation of abscess, early vascular intervention and appropriate debridement, @entity551 can be a useful adjunct to the management of limb-threatening @entity6 .
