Age-related differences in body XXXX in response to altered thyroidal status.

@entity1375 @entity353 @entity3937 @entity1378 @entity35 @entity1954
To determine whether age-related differences in body @entity353 in @entity1378 could be related to caloric intake, the body weight and food consumption of Fischer 344 male @entity35 were monitored every other day for four weeks. Six-month-old (young) @entity35 were compared to 16-month-old @entity35 (intermediate age) and 25-month-old (aged) @entity35 . @entity1375 was induced with 0.025% @entity3937 in the drinking water for four weeks. @entity1378 was induced with @entity1954 (T3) injections (15 micrograms/100 g body weight i.p.) for the last 10 days of observation. A group of young @entity35 pair fed with aged @entity35 was included as a control group. The body weight changes of aged @entity35 were similar to @entity1375 young @entity35 . An index of T3 catabolic effect was calculated based on the net @entity353 and food intake. This index was not different in aged @entity35 compared to young @entity35 . The apparent hypersensitivity of aged @entity35 to T3 as evidenced by excessive @entity353 could totally be attributed to decreased caloric intake. It is concluded that aged @entity35 compared to the young are not more sensitive to the overall catabolic effects of thyroid hormones.
