Age and gender specific pediatric reference intervals for aldolase, amylase, ceruloplasmin, @entity908 kinase, pancreatic amylase, prealbumin, and XXXX .

@entity1 @entity908 @entity414
BACKGROUND: Reference intervals can vary based on age and gender. Proper partitioning is necessary to classify health status in different age groups. METHODS: Seven analytes; aldolase, amylase, ceruloplasmin, @entity908 kinase, pancreatic amylase, prealbumin and @entity414 ; were assayed on Roche Modular P analyzers using serum samples from 1765 @entity1 (867 females and 898 males; age range, 6 months to 17 y). Subjects 6 months up to 7 y were undergoing minor surgical procedures. @entity1 7 to 17 y were apparently healthy. Subjects with significant medical history or who were taking any medications were excluded. RESULTS: Separate reference intervals for @entity1 and @entity1 were required for 33% of the groups. Aldolase showed gender variation in the 6-8, 12-14, and 15-17 y. Amylase was the only analyte that showed no significant gender differences within any age group. Both ceruloplasmin and @entity414 had significant differences between the 12-14 and 15-17 y groups. @entity908 kinase exhibited statistically significant gender differences in all age groups with the exception of 6-8 y. CONCLUSION: We verified that when establishing pediatric reference intervals, partitioning by age and gender is frequently necessary.
