Race is a major determinant of secondary @entity2742 in @entity1381 XXXX .

@entity1 @entity3775 @entity6 @entity177 @entity8611 @entity79 @entity460 @entity1381 @entity3151 @entity2742 @entity461 @entity454
In the general population, blacks have higher parathyroid gland mass and circulating @entity461 ( @entity461 ) levels than whites. This may predispose black @entity1 to more severe @entity8611 when @entity177 develops. Therefore, racial differences in the severity of @entity2742 were examined in a population of @entity1 with @entity454 ( @entity454 ). Among @entity454 @entity1 receiving hemodialysis or peritoneal dialysis, two or more values of intact @entity461 (immunoradiometric assay, pg/ml) obtained at least 90 d apart were available in 1270 prevalent cases (61.1% blacks, 51% males, and 31.1% @entity6 ), including 466 incident cases with onset of @entity454 after 1993. Maximum @entity461 levels were analyzed as a function of race, gender, age, @entity6 status, and levels of serum @entity460 , @entity3151 , alkaline phosphatase, and @entity3775 . Using a stepwise multiple regression model, the determinants of maximum @entity461 in the order of their importance were black race, serum @entity3151 , absence of @entity6 , younger age, serum @entity460 , and female gender. The maximum @entity461 levels averaged 641.7 in blacks and 346.0 in whites after adjusting for age, gender, @entity6 status, serum @entity460 , and @entity3151 (P < 0.0001). In blacks compared with whites, the odds ratio (95% confidence interval) for @entity79 (maximum @entity461 <150 pg/ml) was 0.26 (0.17 to 0.41), whereas the odds ratio for @entity79 (mean @entity461 >500 pg/ml) was 4.4 (2.10 to 9.25). Race is a major independent determinant of @entity1381 secondary @entity2742 . Among @entity454 @entity1 , blacks may be at an increased risk for @entity79 and whites for @entity79 .
