Epidemiological, clinical and laboratorial profile of XXXX : a 12-year retrospective study of 37 cases.

@entity1 @entity644 @entity12042 @entity101 @entity2783 @entity810 @entity1985 @entity811
BACKGROUND: @entity12042 is one of the main differential diagnoses in the investigation of nephrotic @entity644 in adults, especially elderly @entity1 . OBJECTIVES: The aim of this article is to contribute to international research with epidemiologic data of @entity12042 , given the lack of uniformity described in the literature. @entity1 AND METHODS: A retrospective study of 37 cases of @entity12042 diagnosed by kidney biopsy, between 2000 and 2011, considering epidemiological, clinical and laboratory data. RESULTS: Subjects aged between 32 and 80 years. Of the 37 cases, 21 (56.8%) were diagnosed as non-light chain (non- @entity2783 ) @entity12042 and 16 (43.2%) as light chain @entity2783 ( @entity2783 ). There was seen an increase in number of both @entity2783 and non- @entity2783 cases, with a slight predominance in non- @entity2783 . The mean 24-hour @entity644 was 5839.0 mg/day. @entity811 was present in 75% of @entity1 . @entity101 was reported in 34% of @entity1 . @entity810 , occurred in about 10% of @entity1 , and chronic loss of renal function was present in about 5% at diagnosis. CONCLUSIONS: @entity12042 is a disease of increasing incidence. The forms of clinical presentation proved to be variable, but the presence of @entity644 or @entity1985 in elderly @entity1 should always prompt the suspicion of @entity12042 and is a formal indication of renal biopsy.
