Primary Hepatic Tumors With Myxoid Change: Morphologically Unique Hepatic XXXX .

@entity1 @entity8055 @entity4166 @entity96 @entity5 @entity6594 @entity201 @entity20506 @entity3558 @entity7642 @entity157
UNASSIGNED: @entity3558 production in primary @entity96 is typically interpreted as evidence for biliary differentiation. However, we have observed benign and malignant @entity96 that have abundant extracellular myxoid/mucinous material, yet have only evidence of hepatocellular differentiation. To further characterize these unusual findings, 9 cases were identified and further studied. Four cases were @entity6594 , whereas 5 were @entity157 . Extracellular myxoid/mucinous material was diffuse in 7 cases and patchy in 2 cases. The extracellular myxoid/mucinous material was typically weakly @entity7642 positive (N=6) and Alcian blue positive (N=8). All @entity5 were well differentiated, and none had evidence for biliary differentiation by morphology or immunohistochemistry. The @entity6594 arose in nondiabetic and nonobese @entity1 . Both the hepatic @entity8055 were strongly and diffusely HepPar1 positive, @entity4166 negative, and showed loss of @entity20506 protein expression. These findings indicate that extracellular myxoid/mucinous material in isolation should not be interpreted as @entity201 . Furthermore, the unique morphology, the clinical characteristics, and the immunophenotype results suggest that myxoid @entity6594 and @entity157 may be unique @entity5 variants.
