Gender differences in the relationship between body mass index (BMI) changes and the prevalence and severity of wheezing and XXXX in the first year of life.

@entity1 @entity565 @entity1017
BACKGROUND: Rapid @entity1017 has been recently associated with @entity565 at school age, but its influence in respiratory symptoms during infancy is still unknown. METHODS: Answers from 6541 parents living in six different cities of Brazil to the International Study of Wheezing in @entity1 (EISL) questionnaire were analysed. Data from reported weight and height at birth and at one year were used to calculate BMI. Rapid body mass index (BMI) gain was defined by the difference in BMI superior to 1.0z and excessive by the difference superior to 2.0z. RESULTS: Rapid BMI gain was found in 45.8% @entity1 and excessive in 24.4%. @entity1 showed a significantly higher BMI gain than @entity1 . @entity1 with rapid BMI gain showed a significantly higher prevalence of hospitalisation for wheezing (8.8% vs. 6.4%; aOR: 1.4, 95%CI: 1.1-1.8), severe wheezing (18.1% vs. 15.0%; aOR: 1.3, 95%CI: 1.0-1.5) and medical diagnosis of @entity565 (7.5% vs. 5.7%; aOR: 1.3, 95%CI: 1.0-1.7). @entity1 with @entity1017 also had a significantly higher prevalence of hospitalisation for wheezing (9.8% vs. 6.7%; aOR: 1.5, 95%CI: 1.1-2.0) and severe wheezing (18.9% vs. 15.5%; aOR: 1.3, 95%CI: 1.0-1.6). No significant association was found among @entity1 . CONCLUSIONS: The majority of the evaluated @entity1 showed BMI gain above expected in the first year of life. Although more commonly found in @entity1 , rapid and @entity1017 in the first year of life was significantly related to more severe patterns of wheezing in infancy among @entity1 .
