The Role of Ultrasound Elasticity Imaging in Predicting Ileal Fibrosis in XXXX @entity1 .

@entity1 @entity32 @entity82 @entity30
BACKGOUND: Bowel wall @entity82 is associated with a complicated disease behavior in @entity1 with @entity30 ( @entity30 ). The quantitative assessment of @entity82 severity in @entity30 -affected bowel can help clinical decision making. Our aim was to evaluate the feasibility, reliability, and reproducibility of ultrasound elasticity imaging (UEI) toward the assessment of ileal @entity82 in @entity30 @entity1 . METHODS: Twenty-three consecutive @entity1 with @entity30 , elected for surgical resection of the terminal ileum, underwent bowel ultrasound and UEI. Twenty inflammatory @entity30 @entity1 without complications were enrolled as controls. Bowel wall stiffness was evaluated with UEI by means of color scale and quantitative strain ratio measurement. The severity of bowel wall @entity82 and @entity32 were evaluated on histological sections by semiquantitative and quantitative image analysis and used as a reference standard. RESULTS: The UEI strain ratio measurement was significantly correlated with the severity of bowel @entity82 at both semiquantitative and quantitative histological image analysis: it was characterized by an excellent discriminatory ability for severe bowel @entity82 (area under the receiver operating characteristic curve: 0.917; 95% confidence interval, 0.788-1.000). UEI strain ratio measurements were characterized by an excellent interrater agreement. At multivariate analysis, bowel wall @entity82 proved the only independent determinant of the strain ratio. The ileal strain ratio of inflammatory @entity30 @entity1 was significantly lower than in operated @entity30 @entity1 with severe @entity82 . CONCLUSIONS: UEI can be used to assess ileal @entity82 in @entity30 @entity1 .
