The lipoprotein composition of plasma and ascitic fluid in XXXX .

@entity1 @entity82 @entity2204 @entity412 @entity2975 @entity1575 @entity165 @entity28309
Lipoprotein particles were examined in plasma and ascitic fluid from nine @entity1 (5 males and 4 females) with @entity1575 and in plasma from nine control subjects. LDL and HDL fractions were isolated by ultracentrifugation under rate flotation conditions in a @entity28309 . LDL size was analysed by non-denaturing @entity2975 gradient gel electrophoresis. Plasma lipids in cirrhotic @entity1 were markedly reduced compared to controls. Free @entity165 represented 45.3% of the total @entity165 in plasma and 70.4% of the total @entity165 in the ascitic fluid. The total @entity165 - @entity412 ratio was three times higher in the plasma than in the ascitic fluid of cirrhotic @entity1 . The LDL particles had the same flotation properties in plasma from cirrhotic @entity1 as in that from controls. In cirrhotic @entity1 the IDL concentration was higher than that in controls. In ascitic fluid the LDL particles had a higher flotation rate than in the plasma. The LDL diameter as measured by gradient gel electrophoresis was similar in both plasma and ascitic fluid of the cirrhotic @entity1 as well as in the plasma of controls. In plasma and ascitic fluid of cirrhotic @entity1 only a single HDL subclass (HDL1) could be identified. HDL1 particles had a higher flotation rate than normal HDL particles. The plasma levels of all the apoproteins were reduced in cirrhotic subjects compared to controls, but to a variable degree; while apo CII level in @entity82 represented only 9% of the control level, the @entity2204 level represented 77% of the control level.(ABSTRACT TRUNCATED AT 250 WORDS)
