Burnout Is Associated with Reduced Parasympathetic Activity and Reduced XXXX Responsiveness, Predominantly in Males.

@entity1 @entity701 @entity2339 @entity65
UNASSIGNED: There is mounting evidence that burnout is a risk factor for @entity65 ( @entity65 ). Stress-related dysregulation of the sympathetic and parasympathetic system and the @entity2339 may explain the enhanced risk for @entity65 . To test this hypothesis, 55 @entity1 (34 males and 21 females) with burnout on sickness absence and 40 healthy @entity1 (16 males and 24 females) were exposed to a psychosocial stressor consisting of mental arithmetic and public speech. Physiological variables (i.e., blood pressure, heart rate, cardiac output, vascular resistance, @entity701 , and alpha-amylase) were measured. Basal levels, reactivity, and recovery were compared between groups. In male @entity1 , baseline systolic blood pressure was higher, whereas basal alpha-amylase and @entity701 reactivity were lower than in healthy males. In female @entity1 , a tendency for lower basal @entity701 was found as compared to healthy females. Furthermore, reduced basal heart rate variability and a trend for elevated basal cardiac output were observed in both male and female @entity1 . Burnout is characterised by dysregulation of the sympathetic and parasympathetic system and the @entity2339 , which was more pronounced in males than in females. This study further supports burnout as being a risk factor for @entity65 through dysregulation of the sympathetic and parasympathetic system and the @entity2339 .
