Remission after first-episode XXXX : results of a long-term follow-up.

@entity1 @entity1109 @entity161 @entity12269
The aim of this study was to identify the rate and predictors of remission after @entity161 ( @entity161 ). Ninety-three @entity161 @entity1 were followed for at least 12 months and up to 12 years (mean=58.4 months) including monthly assessments with the Brief Psychiatric Rating Scale-Expanded (BPRS), the @entity1109 ( @entity1109 ), and Scale for the Assessment of Negative Symptoms ( @entity12269 ). We also administered the Premorbid Adjustment Scale (PAS). We used the remission criteria recently defined by Andreasen et al. (2005). Fifty-six (59.5%) @entity1 met the remission criteria in the first 24 months of the follow-up period, but 40 (71.5%) of these @entity1 could not maintain their status. However, 23 (57%) of these @entity1 later met the remission criteria again. The remission group @entity1 achieved a higher rate of employment both in the first year and overall. In the logistic regression analysis, lower negative and higher positive symptoms at admission, lower positive symptoms at month 3 of the follow-up, medication compliance in the first 6 months, and occupational status during the last month before admission were found related to remission status. Our findings suggest that the remission group has advantages in terms of occupational status and symptom severity compared with their counterparts who did not achieve or maintain a state of remission.
