Association between serum osteocalcin level and XXXX in Chinese postmenopausal @entity1 .

@entity1 @entity1144 @entity65 @entity1386
BACKGROUND: A low serum osteocalcin level, @entity1144 and postmenopausal status are recognized risk factors for @entity65 . OBJECTIVE: We investigated the relationship between the serum osteocalcin level and visceral fat content in a population of Chinese postmenopausal @entity1 . DESIGN AND @entity1 : In total, 1481 postmenopausal @entity1 (mean age      standard deviation, 57  1      4  8  years) were selected from the Shanghai Obesity Study. MEASUREMENTS: Abdominal fat accumulation was quantified using magnetic resonance imaging. Subjects with a @entity1386 ( @entity1386 ) of >= 80  cm(2) were classified as abdominally obese. The total serum osteocalcin level was measured by electrochemiluminescence immunoassay. RESULTS: The median serum osteocalcin level was 20  66   g/l (interquartile range, 16  88-25  42   g/l). The overall prevalence of @entity1144 was 49  1% (n  =  727). @entity1144 subjects had lower serum osteocalcin levels than did nonabdominally obese subjects [19  14 (16  02-23  82) vs 21  97 (18  14-26  77)  g/l, respectively; P  <  0  001]. Partial correlation analysis showed that the serum osteocalcin level was still negatively correlated with @entity1386 after adjusting for age, years since menopause and body mass index (P  <  0  01). Moreover, @entity1386 was independently associated with the serum osteocalcin level after adjustment for confounding factors (P  <  0  05). A low serum osteocalcin level was an independent risk factor for @entity1144 (odds ratio, 0  972; 95% confidence interval, 0  953-0  991; P  =  0  004). CONCLUSION: The serum osteocalcin level was inversely correlated with the visceral fat content in these Chinese postmenopausal @entity1 .
