Effect of carotid artery stenting on cognitive function in XXXX with @entity543 : a prospective, 3-month-follow-up study.

@entity1 @entity543 @entity2998
BACKGROUND AND PURPOSE: @entity2998 ( @entity2998 ) is emerging as an alternative to carotid endarterectomy for the treatment of @entity543 ( @entity543 ), but the effect of @entity2998 on the cognitive function of @entity1 with severe @entity543 has not been fully investigated. The aim of this study was to use comprehensive neuropsychological tests to determine the effect of @entity2998 on cognitive function from baseline to 3 months postprocedure in @entity1 with severe @entity543 . METHODS: Thirty-one @entity1 due to undergo @entity2998 due to high-grade @entity543 (>= 70%) and 11 control subjects who were diagnosed with @entity543 , but who did not undergo @entity2998 , and who visited the clinic or emergency room between February 2009 and February 2012 were recruited consecutively at baseline (i.e., pre- @entity2998 ). Follow-up neuropsychological evaluations after 3 months were completed by 23 of the 31 @entity1 who underwent @entity2998 , and by 10 of the 11 control subjects. The primary cognitive outcome was assessed using a neuropsychological test containing subcategories designed to test general cognitive function, attention, visuospatial function, language and related functions, memory, and frontal lobe/executive function. RESULTS: Of the 23 @entity1 undergoing @entity2998 who completed the 3-month follow-up tests, 12 had asymptomatic @entity543 . During the 3-month follow-up period, the @entity1 who underwent @entity2998 and those with asymptomatic @entity543 achieved similar results to the control group on all cognitive tests. However, symptomatic @entity543 @entity1 (n=11) who underwent @entity2998 exhibited improvements in visuospatial function (p=0.046) and total Seoul Neuropsychological Screening Battery-Dementia Version scores (p=0.010) in comparison with both the asymptomatic @entity543 @entity1 and the control group. CONCLUSIONS: The findings of this study suggest that @entity2998 has a positive effect on cognitive function in @entity1 with symptomatic @entity543 over a 3-month follow-up period. A long-term, multicenter, prospective case-control study would be helpful to predict quality of life and prognoses for @entity1 undergoing @entity2998 .
