Long-Term Clinical Outcomes of Deep Anterior Lamellar Keratoplasty in XXXX With @entity9042 .

@entity1 @entity940 @entity260 @entity9042 @entity9762
PURPOSE: To report long-term clinical outcomes of @entity9762 ( @entity9762 ) in @entity1 with @entity9042 . DESIGN: Retrospective noncomparative interventional study. METHODS: setting: Single center. @entity1 : Total of 158 eyes/150 consecutive @entity1 with @entity9042 with postoperative follow-up time equal to or greater than 4 years. intervention: @entity9762 . main outcome measure(s): Uncorrected and corrected distance visual acuity (UDVA, CDVA), mean refractive spherical equivalent (MRSE), keratometry, endothelial cell density (ECD). RESULTS: Mean postoperative follow-up was 76.9    23.2 (range 48-120) months. Preoperative UDVA was 20/400 (1.5    0.4 logMAR), CDVA 20/50 (0.7    0.2 logMAR), MRSE  -11.1    5.6 diopters (D), mean keratometry 60.7    6.1 D, topographic @entity940 4.7    2.6 D. At last postoperative follow-up visit, UDVA improved to 20/50 (0.5    0.3 logMAR), CDVA to 20/25 (0.09    0.1 logMAR), MRSE to  -2.6    3.5 D, mean keratometry to 44.4    2.2 D, and topographic @entity940 to 2.9    1.3 D. Postoperative ECD did not vary from preoperative values being 2070.5    367.5 cell/mm(2) and 2198    373 cell/mm(2), respectively, with 70% of eyes (111/158) showing ECD >= 2000 cells/mm(2). Eighteen eyes (11.3 %) developed stromal or epithelial rejection, 3 (1.8%) required regrafting. Eyes with successful big bubble showed greater CDVA than those that required manual dissection at follow-up equal to or less than 5 years but comparable results in the longer term. CONCLUSIONS: @entity9762 provides stable long-term visual and refractive outcomes. Risk of graft rejection, @entity260 , and late ECD decay is reduced when compared to standard penetrating keratoplasty.
