Effect of Transient Post-transplantation @entity4854 on the Development of XXXX and Transplantation Outcomes in Kidney Transplant Recipients.

@entity1 @entity6 @entity413 @entity204 @entity4854 @entity65
BACKGROUND: @entity4854 occurs frequently after kidney transplantation and may be reversed when the dosage of the immunosuppressive agents is tapered. However, the effect of transient post-transplantation @entity4854 (PTH) on transplantation outcomes is not well described. METHODS: Kidney transplant recipients without @entity6 who underwent kidney transplantation between 2001 and 2012 were enrolled in the study. Transient PTH was defined as recovery from PTH without further antidiabetic therapy and the maintenance of glycated hemoglobin levels  <6.5% at 1 year after transplantation. Persistent PTH until 1 year after transplantation was considered to be new-onset @entity6 after transplantation (NODAT). The factors associated with increased risk of PTH were analyzed. We compared the development of @entity6 , @entity65 , and other transplantation outcomes among @entity1 with no PTH, transient PTH, and NODAT. RESULTS: Among 176 kidney transplant recipients, 106 (60.2%) developed PTH and 58 (54.7%) of 106 @entity1 with PTH had transient PTH. Older age, high body mass index (BMI), and female gender were independent risk factors for transient PTH. The incidence of @entity6 was not significantly different between @entity1 with no PTH and those with transient PTH. The incidence of @entity65 was significantly increased in NODAT group compared with that in no PTH and transient PTH groups. However, the incidences of acute rejection, allograft loss, and @entity1 @entity204 were comparable among the three groups. CONCLUSIONS: Transient @entity4854 after kidney transplantation was found to be associated with older age, high body mass index, and female gender. Transient elevation of blood @entity413 level did not affect post-transplantation outcomes, including @entity6 and @entity65 . However, @entity1 with NODAT should be carefully monitored for the occurrence of @entity65 .
