[CLINICOPATHOLOGICAL STUDY OF PROSTATE BIOPSY IN @entity1 RECEIVING XXXX FOR BENIGN PROSTATIC HYPERPLASIA].

@entity1 @entity263 @entity1067 @entity342 @entity16503 @entity1486
OBJECTIVE: @entity16503 is a 5-alpha reductase inhibitor used to treat @entity1067 . @entity16503 lowers @entity1486 levels, which may lead to delays in the diagnosis and treatment of @entity263 ( @entity263 ). This study investigated @entity1 who underwent prostate biopsy (PBx) while receiving @entity16503 to investigate whether this agent affects the diagnosis and treatment of @entity263 . @entity1 AND METHODS: PBx was performed on six @entity1 receiving @entity16503 for > 3 months at our medical institutions between January 2010 and June 2013. No @entity1 underwent PBx before @entity16503 administration. We performed PBx both for @entity1 with high initial @entity1486 levels and for those with elevated @entity1486 levels with or without initial @entity1486 decline after @entity16503 administration. We also investigated clinicopathological findings. RESULTS: Mean age at the start of administration was 69.5    5.9 years (range, 59-77 years), mean duration of administration was 14.1    7.4 months (range, 4.0-23.5 months), mean prostate volume at the start of administration was 70.4    30.7 ml (range, 18.8-104.6 ml), and mean @entity1486 level at the start of administration was 7.7    3.3 ng/ml (range, 4.9-14.2 ng/ml). @entity1486 density was 0.098    0.045 ng/ml/cm3 (range, 0.042-0.181 ng/ml/cm3), and @entity1486 level at PBx was 5.4    2.7 ng/ml (range, 2.5-10.7 ng/ml). We detected three @entity263 @entity1 , and clinical stage in each case was cT1cN0M0. Radical retropubic prostatectomy was performed in two cases, and @entity342 -deprivation therapy was performed in one case. CONCLUSION: All @entity263 were detected in the early clinical stage. No delays in detection or treatment of @entity263 were seen in any cases. Careful observation of @entity1486 levels is simple and useful for detecting @entity263 in @entity1 under @entity16503 administration.
