An evaluation of the SCM test for the diagnosis of XXXX .

@entity5 @entity1 @entity0 @entity941
The SCM test (structuredness of the cytoplasmic matrix) consists of measuring the fluorescence polarization of @entity941 which is introduced into a particular sub-group of peripheral lymphocytes. The test has a non-specific part for the general detection of @entity5 and a specificity procedure which is based on the use of specific @entity5 extracts. In this article we deal only with the latter in relation to @entity0 . Blood samples from 94 @entity1 have been tested; six of these had mastectomy performed previously; 83 underwent consecutively a surgical procedure and histology was obtained; five were only clinically examined. In 45/49 (92%) @entity1 , correlation between a positive specificity test and tissue @entity5 was found. Out of 35 @entity1 with non-malignant proliferative lesions (as found by histology), 25 reacted positively in the test. Two out of five @entity1 with non-malignant, non-proliferative lesions reacted positively in the test. Five @entity1 who were defined as normals by clinical examination reacted negatively in the test. These results indicate the potential of the SCM test for detecting @entity0 . The clinical implications of the test for @entity5 diagnosis are discussed.
