Intra-articular @entity1286 enhances analgesic efficacy of XXXX for knee arthroscopy in ambulatory @entity1 .

@entity1 @entity7988 @entity390 @entity391 @entity5834 @entity1342 @entity158 @entity1286 @entity1443 @entity10425
The aim of this double-blind, randomized control trial was to compare the effectiveness of intra-articular @entity1342 alone or with @entity1286 or @entity7988 for controlling @entity158 after arthroscopic knee surgery. One hundred fifty-six @entity1 scheduled for elective knee arthroscopy were recruited. All @entity1 received general anesthesia and were randomly assigned to 4 groups to receive intra-articular @entity1342 40 mg (group R), @entity1342 24 mg plus @entity1286 8 mg (group R+M), @entity1342 36 mg plus @entity7988 100 mg (group R+K), or normal saline (group N/S). @entity158 , sedation, orientation, @entity390 , @entity391 , and urine retention were recorded at 0, 1, 2, 4, 8, 12, and 24 hours postoperatively. @entity158 was evaluated by a 10-cm visual analog scale (VAS). When the @entity158 was >2, a suppository of 400 mg @entity1443 plus 10 mg @entity10425 plus 50 mg @entity5834 was given. Results showed that at 4 hours postoperatively, @entity158 differed significantly among the 4 groups (P<.001), with @entity158 recorded in the R+M group. Similarly, the number of suppositories administered postoperatively to the R+M group was significantly less (P<.001) vs the other groups. @entity1 who received @entity1342 and @entity1286 or normal saline had a higher incidence of @entity390 and @entity391 vs the other groups (P=.001 and P=.036, respectively). The combination of intra-articular @entity1342 and @entity1286 is associated with @entity158 after knee arthroscopy during early recovery but with a higher incidence of @entity390 and @entity391 . However, the addition of @entity7988 to @entity1342 provides relatively satisfactory @entity158 relief, but with fewer side effects compared to @entity1286 .
