Preterm premature XXXX is associated with a reduction in neonatal respiratory distress syndrome.

@entity1 @entity3152 @entity649 @entity5935 @entity397
OBJECTIVE: The purpose of this study was to evaluate the effect of preterm premature @entity397 on the frequency of @entity649 among singleton pregnancies that are complicated with @entity3152 . STUDY DESIGN: We performed a retrospective analysis of singleton pregnancies that were delivered between 24 and 34 weeks of gestation. @entity1 were categorized on the basis of membrane integrity into two groups: ruptured versus intact. All @entity1 received prophylactic antibiotics and a single course of antenatal @entity5935 . Data were analyzed with the Student t test, the chi(2) test, and the Fisher exact test. Multiple logistic regression analysis was performed to examine the effect of possible confounding variables that were considered risk factors for @entity649 . Probability values of <.05 for all two-tailed tests were considered significant. RESULTS: A total of 366 @entity1 were included (99 @entity1 in the preterm premature @entity397 group and 267 @entity1 in the intact membranes group). @entity1 were delivered at 30.7 +/- 2.9 and 30.1 +/- 2.7 (mean +/- SD) weeks of gestation, with birth weights of 1620 +/- 594 and 1417 +/- 501 g, respectively. The frequency of @entity649 in the neonate was significantly lower in the preterm premature @entity397 group than in their intact counterparts (17% vs 39%, P <.001). Multiple logistic regression analysis confirmed that preterm premature @entity397 (odds ratio, 0.16; 95% CI, 0.08-0.34) was independently associated with a reduction in the frequency of @entity649 . CONCLUSION: In the clinical setting of delivery before 34 weeks of gestation, preterm premature @entity397 is associated with a significant decrease in the frequency of neonatal @entity649 .
