Measuring the symptom @entity2 : the validity and utility of the XXXX module of the M. D. Anderson Symptom Inventory.

@entity1 @entity1142 @entity2 @entity5
We conducted a study to establish the psychometric properties of a module of the M. D. Anderson Symptom Inventory (MDASI) developed specifically for @entity1 with @entity2 (MDASI-LC). The MDASI measures 13 common "core" symptoms of @entity5 and its treatment. The MDASI-LC includes the 13 core MDASI symptom items and three @entity2 -specific items: coughing, @entity1142 , and sore throat. MDASI-LC items were administered to three cohorts of @entity1 with @entity2 undergoing either chemotherapy or chemoradiotherapy. Known-group validity and criterion (concurrent) validity of the MDASI-LC were evaluated using the Eastern Cooperative Oncology Group performance status and the 12-item Short-Form Health Survey. The internal consistency and test-retest reliability of the module were adequate, with Cronbach coefficient a-values of 0.83 or higher for all module items and subscales. The sensitivity of the MDASI-LC to changes in @entity1 performance status (disease progression) and to continuing @entity5 treatment (effects of treatment) was established. Cognitive debriefing of a subset of @entity1 provided evidence for content validity and indicated that the MDASI core items and three additional @entity2 -specific items were clear, relevant to @entity1 , and easy to understand; only two @entity1 suggested additional symptom items. As expected, the item "sore throat" was sensitive only for @entity1 receiving chemoradiotherapy. The MDASI-LC is a valid, reliable, and sensitive symptom-assessment instrument whose use can enhance clinical studies of symptom status in @entity1 with @entity2 and epidemiological and prevalence studies of symptom severity across various @entity5 types.
