Monitoring XXXX therapy in osteoporosis by dual photon absorptiometry.

@entity1 @entity172 @entity16771 @entity1388 @entity229 @entity460 @entity6092 @entity560
Dual photon absorptiometry (DPA) was used to evaluate changes in bone mineral mass in 108 @entity6092 @entity1 . Ninety were treated with @entity1388 and 18 served as controls. All @entity6092 @entity1 and 9 of the controls took @entity460 and @entity560 supplements. In 16 @entity1 @entity172 were combined with the @entity1388 therapy. Seven @entity1 received @entity229 . Significant positive changes in bone mineral mass in the lumbar spine could be demonstrated over a mean observation time of 14-15 months in all groups treated with @entity1388 but not in the control group. The average increase in bone mineral mass in the lumbar spine (L2, L3 and L4 combined) ranged from 3.57% +/- 1.42% (sem, p less than 0.05) in @entity1 on @entity1388 to 10.36% +/- 3.17% (p less than 0.01) in @entity1 and 10.18% +/- 2.39% (p less than 0.001) in @entity1 on @entity172 and @entity1388 . Changes in bone mineral mass in femoral necks (left and right combined) and femoral diaphysis were not significant. In the control group no significant changes were observed (lumbar spine: -1.68% +/- 1.75%, femoral necks -0.09% +/- 3.3% and femoral diaphysis -2.32% +/- 2.40%). It is concluded that a positive effect of @entity1388 on trabecular bone in the spine can be demonstrated with @entity16771 on a group basis when data processing is done in a uniform way by a single observer. Its longitudinal use in individual @entity1 necessitates a series of measurements to overcome the analytical error.
