Hypolipidaemic effects of Citrullus colocynthis L. in XXXX .

@entity167 @entity1674 @entity95 @entity165
Aim of this research to study the effect of Citrullus colocynthis (70% @entity167 ) extract on lipid profile on @entity95 . The plant extract was orally administered to the atherogenic @entity95 (atherogenic diet + @entity165 powder supplement 400 mg/kg/body weight/day dissolved in 5 mL coconut oil) at dose of 1.2 g kg(-1) body weight/day. During the hall period of the experiment blood was collected and serum was analyzed for lipid profile. Animals were sacrificed; the heart and the liver were collected and kept at -20 degrees C until assayed. Biochemical analysis of blood serum and tissue (liver and heart muscle) level were made for @entity165 , Phospholipids and @entity1674 . In addition blood serum was analyzed further for HDL- @entity165 . All the results were statistically analyzed using students t-test. Hypolipidaemic nature of Citrullus colocynthis (70% @entity167 ) extract was studied in hyperlipidaemic @entity95 . The increased @entity165 levels were brought to normal by administration of Citrullus colocynthis. Serum @entity165 levels dropped from 940.7 to 230.41 (75.55%) and further to 119.2 (87.32%) by the end of the experiment. Similarly, phospholipids and @entity1674 levels were observed to be also reduced. The tissues lipids profiles of liver and heart muscle showed similar changes in those noticed in serum lipids. Citrullus colocynthis possesses active hypolipidaemic constituents.
