XXXX in Iran: analysis of 6500 cases.

@entity1 @entity625 @entity8528 @entity3527 @entity3892 @entity1596 @entity4932 @entity1691 @entity439 @entity358 @entity4216 @entity4841 @entity715 @entity2403 @entity4816 @entity5406
OBJECTIVE: To identify the clinical picture of @entity2403 in a large cohort of @entity1 (6500) in Iran, over a period of 35 years, and compare them with other large series from around the world. METHODS: @entity1 with @entity2403 from all over Iran were seen in the Behcet's Disease Research Unit by a multidisciplinary team (rheumatologists, dermatologists, and ophthalmologists). Diagnosis was based on 'expert opinion'. Data were collected on a standardized data sheet (105 items), and stored in an electronic database. Data were updated at each follow-up. RESULTS: Male to female ratio was 1.22 :    .00. The mean age at onset was 26 years    11.3. The frequency of symptoms were: oral aphthosis 97.3%, genital aphthosis 64.6%, skin manifestations 64.9% ( @entity8528 54.5%, @entity5406 22.5%, other lesions 7%), pathergy phenomenon 52.5%, ophthalmologic manifes-tations 56.8% (anterior @entity1596 41.2%, posterior @entity1596 44.9%, @entity4816 32.1%), joint manifestations 37.4% ( @entity4841 17.2%, monoarticular @entity625 7.6%, @entity4932 16.8%, @entity1691 2%), neurological manifestations 3.8% (central manifestations 3.5%, @entity4216 multiplex 0.3%), gastrointestinal manifestations 7.4%, vascular involvement 8.3% ( @entity3527 5.7%, superficial @entity3527 2.2%, large vein @entity715 1.1%, arterial @entity715 0.154%, @entity439 0.5%), @entity3892 4.7%, cardiac involvement 0.6%, and @entity358 .9%. Sedimentation rate was normal in 46.5% of @entity1 . Abnormal urine sediment was detected in 12.2%. HLA-B5 was present in 53.3% and HLA-B51 in 47.9% of @entity1 . CONCLUSION: @entity2403 is mainly seen in young @entity1 . The most frequent symptoms are mucocutaneous, ocular and joint manifestations. Comparison with large series did not show major differences.
