Features of time-intensity curve parameters of XXXX evaluated by double-contrast enhanced ultrasonography: initial observation.

@entity1 @entity39 @entity5 @entity1054 @entity14 @entity420
PURPOSE: This study is to investigate the value of double contrast-enhanced ultrasonography (DCEU) in assessing microcirculation of @entity14 and to describe the perfusion features of the @entity5 . MATERIAL AND METHODS: DCEUS was performed in 42 @entity1 with @entity420 . The time-intensity curve parameters ( @entity1054 ( @entity1054 ), @entity1054 ( @entity1054 ), peak intensity (PI) and area under the curve (AUC)) within the @entity5 were extracted. The parameters were compared among the @entity5 with different CEUS features and stages. RESULTS: The mean values of @entity1054 , @entity1054 , PI and AUC of the @entity14 were 13.68  13.36s, 32.61  19.56s, 19.82  16.54dB and 271.10  159.19dBs, respectively. In the @entity420 with @entity39 , the mean values of AUC was significantly lower than that of the @entity420 without (231.10  219.27dBs, 278.10  123.20dBs, p=0.004). In the @entity420 with @entity39 , the AUC and PI of the non-necrotic part were significantly higher than that of the necrotic part (p=0.007, 0.0025, respectively). AUC increased progressively in the subgroups of T2, T3 and T4 and the difference of AUC between T2 and T4 subgroup was significant (p=0.008). CONCLUSIONS: Double contrast-enhanced ultrasonography is a valuable technique for quantifying @entity5 vascularity of @entity14 . AUC was significantly different in the subgroups of different T stage. AUC and PI could reflect the different perfusion status of @entity5 with or without @entity39 .
