Analysis of a viridans group strain reveals a case of bacteremia due to lancefield group G alpha-hemolytic XXXX in a @entity1 with @entity6735 and @entity625 .

@entity1 @entity625 @entity3637 @entity1219 @entity30180 @entity535 @entity22193 @entity6735
@entity22193 is classified by a combination of phenotypic and genotypic characteristics into Lancefield group C alpha-hemolytic @entity22193 . dysgalactiae and Lancefield group C, group G, and group L beta-hemolytic @entity30180 . In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and @entity3637 -resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% @entity1219 , from the blood culture of a 73-year-old @entity1 with @entity6735 and poststreptococcal @entity625 . Lancefield grouping revealed that the strain was a group G @entity30180 . The Vitek system (GPI) showed that it was unidentified, and the API system (20 STREP) showed that it was 95.7% @entity22193 . dysgalactiae. 16S rRNA gene sequencing showed that it was a strain of @entity22193 . Based on phylogenetic affiliation with 16S rRNA gene or GroEL @entity535 (another bacterial gene, in addition to 16S rRNA gene, that is highly conserved) sequences, the strain is most closely related to Lancefield group C beta-hemolytic @entity30180 . PCR amplification and sequencing of the streptolysin S structural gene (sagA) and M protein gene (emm) hypervariable region showed the presence of these suspected primary virulence factors. Further studies would delineate whether the isolate is just a hemolysin-deficient variant of group G beta-hemolytic @entity30180 or a novel type of @entity22193 . The present case showed that group G alpha-hemolytic @entity30180 can be associated with serious invasive infection and poststreptococcal sequelae.
