XXXX in Kuwait: a review of 90 cases.

@entity1 @entity625 @entity9916 @entity4272 @entity31 @entity1960 @entity14 @entity4841 @entity1141
BACKGROUND: Chronic @entity31 is a disease of unknown etiology. Its incidence is on the rise in various developing countries as has been reported in studies from South-East Asia and the Middle East. There seems to be significant differences in the pattern and the clinical course of this disease in our @entity1 population. The aim of our study is to assess the incidence and the clinical course of the disease in Kuwait. METHODS: This is a retrospective study of cases identified over a period of 14 years (1985-1999). Three hundred forty-six @entity1 were identified to have chronic @entity31 . Ninety @entity1 were interviewed for this study. RESULTS: Chronic @entity31 is being identified with increasing frequency. Our local incidence was 2.8 per 100,000 @entity1 per year. The disease was seen in both sexes with equal frequency. It peaks at the third decade of life, with no second peak observed in the sixth decade. The disease was of mild to moderate severity in 93% of the cases. The distribution of the disease in the colon showed pancolitis in 45%, left-sided @entity1960 in 14%, @entity9916 in 21% and @entity4272 in 20%. @entity625 and @entity4841 were the most frequent extraintestinal manifestation seen in 31%. Perianal disease, although rare in @entity31 , was seen in 8%. Of interest is the fact that over 14 years of follow-up, none of our @entity1 developed high-grade @entity1141 or @entity14 . Four @entity1 required total colectomy mainly due to failure of medical therapy. CONCLUSIONS: Chronic @entity31 is occurring with increasing frequency similar to that seen in Western countries. The disease observed in our @entity1 population was of mild to moderate severity, with fewer complications than reported in Western countries. It peaks in the third decade with no second peak. None of our @entity1 developed high-grade @entity1141 or @entity14 .
