Impact of Device-Associated Infection on @entity130 XXXX Outcomes at a @entity130 Center.

@entity1 @entity295 @entity281 @entity2489 @entity764 @entity204 @entity293 @entity130
BACKGROUND: Catheter-associated @entity293 (CAUTI) and @entity2489 ( @entity2489 ) are considered performance measures. We analyzed the incidence, prevalence, and risk of CAUTI and @entity2489 in @entity130 @entity1 , as well as the demographic and injury factors related to these @entity281 and their relative risks of negative outcomes (prolonged length of stay [LOS], @entity295 , and @entity204 ). METHODS: @entity130 registry data were analyzed (age >18   y; LOS >24   h) from January 1, 2007, to December 31, 2011. @entity130 location, severity, and type were analyzed relative to outcomes along with device-associated @entity281 , as defined by the U.S. Centers for Disease Control and Prevention. The outcomes analyzed were intensive care unit (ICU) and hospital LOS, @entity295 , and in-hospital @entity204 . Multivariable logistic regression was then used to identify the factors contributing to @entity295 , including device-associated @entity281 . RESULTS: The included population (n=10,755) was 66.6% male and had a mean age of 45.1   y, with blunt @entity130 in 91.8% and a median Injury Severity Score (ISS) of 10 points. @entity1 developing CAUTI (n=324; 3.0%; p<0.005) were more likely to be female (59.4%), had a higher median ISS (20.5), and were older (56.7 years). @entity1 with @entity2489 (n=161; 1.5%; p<0.005) had a higher median ISS (27). @entity1 with @entity295 (n=149; 1.4%; p<0.005) had a higher median ISS (24.0) and were older (52.3   y). @entity295 was associated with prolonged LOS and @entity204 , as expected (p<0.005). In multivariable analysis, independent predictors of @entity295 were CAUTI (odds ratio [OR] 16.15; p<0.001), @entity2489 (OR 6.95; p<0.001), ISS (OR 1.05 per unit; p<0.001), age (OR 1.02 per year; p<0.001), and penetrating, abdominal, pelvic, or @entity764 . CONCLUSION: Development of CAUTI and @entity2489 are significantly associated with a higher risk of @entity295 in @entity130 @entity1 after adjustment for age and @entity130 , location, and severity. This study suggests the importance of device-associated @entity281 as vectors for @entity295 in @entity130 and highlights the importance of prevention initiatives.
