@entity150 : the primacy of grade in the development of XXXX .

@entity1 @entity5 @entity189 @entity150 @entity3 @entity11090
Tumor characteristics thought to predict for development of @entity11090 after resection of superficial @entity150 were retrospectively analyzed in 252 @entity1 with transitional cell @entity150 at Stanford University Medical Center. Stage 0 @entity1 accounted for 190 of the @entity1 population (75.5%), while stage A and B1 comprised 51 (20%) and 11 (4.5%), respectively. The median follow-up time was 62 months. Forty-three @entity1 subsequently developed @entity11090 ; these included 24 (12.6%), 14 (27.5%), and 5 (45.5%) of stage 0, A, and B1 @entity1 (P = .002), or 15 (10%), 15 (9%), and 13 (33%) of grade 1, 2, and 3 @entity5 (P = .001), respectively. When analyzed by univariate logistic regression, grade (P = .0001) and stage (P = .0118) were significant predictors for @entity3 . Site of @entity5 and number of @entity5 at presentation were not significant factors for invasion deep into the bladder wall. When multiple logistic regression was performed, only grade remained as a significant @entity5 variable to predict for @entity3 (P less than .0091). Risk of @entity3 did not appear to increase with increasing number of recurrences, remaining at approximately an 11% invasion rate through 12 recurrences. In this analysis, grade was the most significant @entity5 variable in superficial @entity150 predicting for the development of @entity189 . Future clinical trials for definitive or adjuvant therapy of this disease must stratify for this variable.
