Impact of preexisting XXXX detected by magnetic resonance imaging and angiography on late outcome after coronary artery bypass surgery.

@entity1 @entity1095 @entity64 @entity2806 @entity63
BACKGROUND: The aim of this study was to assess the impact of preexisting @entity63 detected by brain magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) on long-term survival, and cardiac and neurologic events after coronary artery bypass grafting (CABG). METHODS: Of 923 @entity1 who underwent CABG between 1994 and 2007, 887 @entity1 (96.1%) were followed up. Preoperative brain MRI and MRA were performed in 619 @entity1 . @entity63 was detected by brain MRI and MRA in 158 @entity1 (group A), but not in 461 @entity1 (group B). Preoperative characteristics, follow-up survival, and cardiac and neurological events were investigated. RESULTS: The average follow-up period was 6.0    4.3 years. Univariate analysis showed that @entity1 in group A (68.5    6.5 years) were older than those in group B (64.5    8.6 years) (p = 0.0001). Preoperative left ventricular ejection fraction was less in group A (0.516    0.175) than in group B (0.556    0.165) (p = 0.02). The prevalence of @entity1095 was higher in group A (14 @entity1 : 8.9%) than in group B (11 @entity1 : 2.4%) (p = 0.001). The rate of on-pump CABG was lower in group A (115 @entity1 ; 72.8%) than in group B (383 @entity1 ; 83.1%) (p = 0.007). Survival rate was significantly lower (p = 0.062), and freedom from major adverse cardiac event or @entity64 were significantly lower in group A (p = 0.0002, and p = 0.0001, respectively; log-rank test). However, the Cox proportional hazard model showed that preoperative @entity2806 detected by brain MRI and MRA affected only freedom from neurologic events (p = 0.02; hazard ratio 2.52; 95% confidence interval 1.13 to 5.62), but not survival (p = 0.67) or major adverse cardiac event (p = 0.09). CONCLUSIONS: Preexisting ischemic findings on brain MRI and MRA in @entity1 who underwent CABG were related only to long-term freedom from @entity64 , but were not related to survival or major adverse cardiac event.
