Menstrual induction with @entity3927 and XXXX .

@entity1 @entity6003 @entity5852 @entity396 @entity3009 @entity3927
Menstrual induction refers to early uterine evacuation without laboratory confirmation of pregnancy in @entity1 with delayed menses. Mechanical aspiration is the method used in many countries but, as suggested by a pilot study, @entity3927 followed by a @entity3009 analogue could also be effective. We launched the present study to evaluate the efficacy and side effects of 150 mg of @entity3927 , followed 2 days later by 0.4 mg @entity396 vaginally, for menstrual induction among @entity1 with a menstrual delay of up to 7 days. The outcome of treatment was uterine evacuation, which could mean menstruation or termination of early pregnancy. A total of 720 @entity1 were recruited. The mean delay of menstruation at recruitment was 4.9 (SD = 1.7) days. Retrospective analysis of @entity1 chorionic gonadotropin from serum samples taken at admission showed that 492 (68.3%) @entity1 were pregnant at admission, and 228 (31.7%) @entity1 had delayed menstruation without pregnancy. One nonpregnant @entity1 was lost to follow-up. Bleeding was induced in 479 (97.4%) pregnant @entity1 and in 222 (97.8%) nonpregnant @entity1 . Among the pregnant @entity1 , 455 (92.5%) had @entity5852 , 12 (2.4%) had @entity6003 and pregnancy continued in 25 (5.1%) @entity1 , including one ectopic pregnancy. Side effects were mild and uncommon. We conclude that 95.8% of the @entity1 treated had the expected outcome. Further research is needed to compare the efficacy, safety and acceptability of the medical regimen to vacuum aspiration. A rather high continuing pregnancy rate in this study is a concern.
