Erectile function following brachytherapy, external beam radiotherapy, or radical prostatectomy in XXXX @entity1 .

@entity1 @entity323 @entity263
BACKGROUND AND PURPOSE: For @entity263 , treatment options include external beam radiotherapy (EBRT), radical prostatectomy (RP), and brachytherapy (BT). @entity323 ( @entity323 ) is a common side-effect. Our aim was to evaluate penile @entity323 ( @entity323 ) before and after BT, EBRT, or RP using a validated self-administered quality-of-life survey from a prospective registry. MATERIAL AND METHODS: Analysis included 478 @entity1 undergoing RP (n   =   252), EBRT (n   =   91), and BT (n   =   135) with at least 1 year of follow-up and @entity323 documented using IIEF-5 scores at baseline, 6 weeks, 6 months, 1 year, and annually thereafter. RESULTS: Differences among treatments were most pronounced among @entity1 with no or mild initial @entity323 (IIEF-5   >=    17). Overall, corrected for baseline @entity323 and age, BT was associated with higher IIEF-5 scores than RP (+   7.8 IIEF-5 score) or EBRT (+   3.1 IIEF-5 score). EBRT was associated with better IIEF-5 scores than RP (+   4.7 IIEF-5 score). In @entity1 undergoing EBRT or RP with bilateral nerve sparing (NS), recovery of @entity323 was observed and during follow-up, the differences to BT were not statistically significant. Overall age had a negative impact on @entity323 preservation (corrected for baseline IIEF). CONCLUSION: In our series, @entity323 was adversely affected by each treatment modality. Considered overall, BT provided the best @entity323 preservation in comparison to EBRT or RP.
