Surgical outcome of spinal XXXX @entity3 .

@entity1 @entity157 @entity1274 @entity3
BACKGROUND: @entity157 ( @entity157 ) @entity3 are increasing with improved survival of @entity1 with @entity157 . However, its treatment outcome, particularly regarding functional outcome, has not been adequately investigated. OBJECTIVE: To present the surgical outcome of spinal @entity157 @entity3 and demonstrate prognostic factors for survival and ambulation time. METHODS: Thirty-three @entity1 (30 males, 3 females) were retrospectively reviewed. @entity1 -Pugh classification was used to assess hepatic function. Preoperatively, 19 @entity1 could ambulate (group A) and 14 @entity1 could not (group B). Preoperatively, 18 @entity1 received conventional fractionated radiotherapy. RESULTS: The spinal @entity3 were removed to achieve sufficient @entity1274 . If destabilization developed, instrumentation and/or vertebroplasty were performed. Postoperatively, conventional radiotherapy was administered to 13 @entity1 . @entity1 survived for 203    31 days. @entity1 -Pugh classification and preoperative/postoperative ambulatory ability were correlated with survival time, with @entity1 -Pugh classification being the most significant factor (hazard ratio, 3.75; 95% confidence interval: 1.38-10.22). After the operation, ambulatory ability was maintained in all group A @entity1 and was recovered in 4 in group B. Twenty-three @entity1 could ambulate for 285    62 days. Preoperative ambulatory status and @entity1 -Pugh classification were correlated with a longer ambulatory period, with preoperative ambulatory status most significant (hazard ratio, 8.62; 95% confidence interval: 2.39-31.04). @entity1 died 81    71 days after the loss of ambulatory ability, regardless of postoperative ambulatory status. CONCLUSION: In spinal @entity157 metastasis, ambulatory status and hepatic function were significantly correlated with survival and ambulation time. Both ambulatory status and hepatic function should be considered in the selection of surgical candidates.
