Outcome after Simultaneous Resection of XXXX and Synchronous Liver Metastases: Survival Analysis of a Single-center Experience in China.

@entity1 @entity96 @entity5 @entity75 @entity3 @entity356
BACKGROUND: The optimal surgical strategy for the treatment of synchronous resectable @entity96 remains controversial. The aims of this study were to analyze the outcome and overall survival of @entity1 presenting with @entity356 and liver @entity3 treated by simultaneous resection. MATERIALS AND METHODS: Between January 1990 and June 2009, 35 @entity1 diagnosed with synchronous hepatic @entity3 from @entity356 received simultaneous resection of both primary @entity356 and synchronous hepatic @entity3 . The clinicopathologic features and the surgical results of the 35 @entity1 were retrospectively analyzed. RESULTS: The 5-year overall survival rate after surgery was 14.3%. Five @entity1 survived for more than 5 years after surgery. No mortality has occurred within 30 days after resection, although two @entity1 (5.7%) developed complications during the peri-operative course. Univariate analysis revealed that @entity1 with the presence of lymphovascular invasion of the @entity5 , bilateral liver @entity3 and multiple liver @entity3 suffered poor survival. Lymphovascular invasion by the @entity75 and multiple liver @entity3 were significant prognostic factors that influenced survival in the multivariate analysis (p=0.02, p=0.001, respectively). CONCLUSIONS: The presence of lymphovascular invasion of the @entity5 and multiple liver @entity3 are significant prognostic determinants of survival. @entity356 @entity1 without lymphovascular invasion and with a solitary synchronous liver @entity3 may be good candidates for hepatic resection. Simultaneous resection of both primary @entity356 and synchronous hepatic @entity3 may effectively prolong survival in strictly selected @entity1 .
