A randomized controlled trial of a 10week group psychotherapeutic treatment added to standard medical treatment in XXXX with @entity2210 .

@entity1 @entity922 @entity2210 @entity34
OBJECTIVE: Epidemiological evidence suggests an association between @entity2210 ( @entity2210 ). Yet few randomized controlled trials (RCTs) of psychological interventions have been conducted for @entity2210 . We conducted an RCT to evaluate the efficacy of psychotherapy among chronic @entity2210 . METHODS: One hundred fifty-eight consecutive @entity1 with @entity2210 were randomized to medical therapy plus psychotherapy consisted in 8 group and 2 individual sessions focused on teaching techniques for coping with @entity2210 ( @entity34 ( @entity34 ); n=76) or medical therapy alone ( @entity34 ( @entity34 ); n=82). @entity1 completed validated self-reported questionnaires before and after the 10-week treatment and 6months later. Linear mixed-effects models were used, in intention-to-treat analysis. RESULTS: At the end of treatment period, statistically significant improvements were observed for @entity34 compared with @entity34 for @entity2210 -related quality of life (DRQoL). DRQoL mean changes of 6.09 and 3.54 were obtained in @entity34 and @entity34 @entity1 , respectively (p=<0.0001); and SS mean changes of 11.55 and 4.57 were obtained in @entity34 and @entity34 @entity1 , respectively (p=0.0013). Those improvements, measured by @entity922 ( @entity922 ), were clinically significant (DRQoL: 77% of the @entity34 @entity1 exceeded the @entity922 vs the 45% of the @entity34 ; SS: 75% vs 48%). Six months after treatment, those statistically significant improvements persisted for DRQoL (p=0.0067) and for SS (p=0.0405). Clinical improvements persisted for SS (63% vs 41%). CONCLUSIONS: These findings suggest that adding psychotherapy to standard medical therapy improves short-term outcomes in @entity1 with @entity2210 and may have long-term effects as well. The cost-effectiveness of intensive therapy needs to be evaluated. Registration number and name of trial registry: NCT01802710.
