Does XXXX -based anti- @entity170 medication affect @entity3604 healing?

@entity3604 @entity1 @entity174 @entity170 @entity5520 @entity717
Effects of @entity5520 on @entity174 healing were prospectively investigated for @entity3604 . Although there were no significant differences in clinical outcomes, the presence of intravertebral cleft was related to the medication use. These results suggest that suspension of @entity5520 use should be considered during the @entity174 healing period. INTRODUCTION: The purpose of this prospective study is to investigate whether @entity5520 -based anti- @entity170 medication affects @entity174 healing and clinical outcomes of conservatively treated @entity3604 ( @entity3604 ). METHODS: A total of 105 @entity1 who were diagnosed with acute @entity3604 were prospectively enrolled. According to their previous medication history, the @entity1 were allocated into group I (n   =   39, no history of @entity5520 use) or group II (n   =   66, history of @entity5520 use). Clinical outcomes were assessed using visual analogue scale (VAS), and @entity717 index (ODI). Radiographic parameters including changes in height loss and kyphotic angle at the index vertebra were measured, and radiographic findings suggesting impaired @entity174 healing such as the intravertebral cleft (IVC) sign and @entity174 instability were evaluated. Univariate and multivariate regression analyses were used to identify related factors. RESULTS: There were no significant differences in the last VAS and ODI between groups. There were also no significant differences in the radiographic parameters. Although the IVC sign was seen more commonly in group II (30.3  %) than in group I (20.5  %), @entity174 instability combined with IVC was noted in the same number of cases. On multiple regression analysis, medication history showed no significant relationship with the clinical parameters. However, the presence of the IVC sign was related to medication history (odds ratio 4.8; 95  % confidence interval [CI] 1.02-22.69). CONCLUSIONS: @entity5520 use does not significantly affect the clinical results during conservative treatment for @entity3604 . However, the occurrence of the IVC sign was related to medication history. Although further studies are needed to verify our findings, these results suggest that suspension of @entity5520 use should be considered during the @entity174 healing period for acute @entity3604 .
