Psychosocial variables affect the quality of life of @entity1 diagnosed with chronic XXXX /chronic @entity2371 .

@entity1 @entity308 @entity1069 @entity2371 @entity158 @entity2723
OBJECTIVE: To examine interactions between demographic, @entity158 , urinary, psychological and environmental predictors of quality of life (QOL) in @entity1 with chronic @entity1069 /chronic @entity2371 ( @entity2723 /CPPS). @entity1 AND METHODS: In all, 253 @entity1 previously enrolled in the National Institutes of Health @entity1069 Cohort study in North American tertiary-care clinical centres (six in the USA and one in Canada) self-reported with validated instruments, including the QOL subscales of the Short Form-12 (physical, SF12-PCS; and mental, SF12-MCS), demographics, urinary symptoms, @entity308 , current @entity158 , @entity158 coping, 'catastrophizing' (catastrophic thinking about @entity158 ), @entity158 control, social support and solicitous responses from a partner. Data were collected through a one-time survey. Covariates determined to be significant were entered into a multivariable regression model predicting SF12-PCS and SF12-MCS. RESULTS: Adjusting for covariates, regression models showed that poorer SF12-PCS scores were predicted by worse urinary function (P < 0.001) and increased use of @entity158 -contingent resting as a coping strategy (P = 0.026). Further, poorer SF12-MCS scores were predicted by greater @entity158 catastrophizing (P = 0.002) and lower perceptions of social support (P< 0.001). In separate follow-up analyses, helplessness was the significant catastrophizing subscale (P < 0.001), while support from family and friends were the significant social support subscales (P = 0.002 and <0.001). CONCLUSIONS: These data suggest that specific coping and environmental factors (i.e. catastrophizing, @entity158 -contingent resting, social support) are significant in understanding how @entity1 with @entity2723 /CPPS adjust. These data can be used to develop specific cognitive-behavioural programmes for @entity1 with @entity2723 /CPPS who are refractory to standard medical therapy.
