@entity4422 and XXXX : a murine model.

@entity3256 @entity4422 @entity174 @entity794 @entity79 @entity281 @entity325 @entity35 @entity2057 @entity3064 @entity121 @entity130
Modern warfare has caused a large number of severe @entity130 , many of which become infected. In more recent conflicts, a pattern of @entity325 with @entity3064 and @entity3256 -resistant @entity794 has emerged. We attempted to recreate this pattern in an animal model to evaluate the role of vascularity in contaminated @entity4422 . Historically, it has been observed that infected bones frequently appear hypovascular, but vascularity in association with @entity79 has not been examined in animal models. Adult @entity35 underwent femur @entity174 and @entity121 followed by stabilization and bacterial contamination with A. baumannii complex and @entity3256 -resistant @entity794 . Vascularity and perfusion were assessed by microCT angiography and SPECT scanning, respectively, at 1, 2 and 4 weeks after injury. Quantitative bacterial cultures were also obtained. Multi-bacterial @entity281 were successfully created, with @entity3256 -resistant @entity794 predominating. There was overall increase in blood flow to injured limbs that was markedly greater in bacteria-inoculated limbs. Vessel volume was greater in the infected group. @entity2057 was seen in both groups, but was greater in the infected group. In this animal model, @entity4422 had greater perfusion and vascularity than non-infected limbs.
