[Efectiveness of topical therapies in XXXX with @entity0 that experience @entity20787 . A systematic review].

@entity1 @entity137 @entity0 @entity111 @entity20787 @entity1217 @entity2636 @entity4722 @entity288
BACKGROUND: After radiation therapy most @entity1 experience @entity137 to some degree. The purpose of this systematic review is to assess the available evidence concerning the effectivity of topical therapies on @entity1 with @entity0 that experience @entity20787 after radiotherapy. METHOD: The review included clinical trials aimed to evaluate topical therapies for prevention or treatment of acute @entity20787 in @entity1 with @entity0 , which were published between 2009 and 2014. The bibliographic search was carried out in the following databases: PubMed, Cinahl, Cochrane Plus, IBECS and LILACS. The studies were selected independently by peer reviewers using the Critical Appraisal Skills Programme in its Spanish version. RESULTS: 86 bibliographical references were identified. Twenty full-text articles of clinical trials were assessed and two were excluded because they were not completed; 12 of clinical trials evaluated topical treatment with creams and ointments, three with corticosteroid creams and other three with dressings. The effectivity of @entity1 epidermal growth factor cream, @entity4722 emulsion, topical @entity1217 , @entity288 creams and @entity2636 dressings has been shown in these clinical trials. CONCLUSIONS: Given that @entity20787 is a dynamic process, these topical agents were effective in different stages of @entity137 . Some of them delayed the onset, others decreased the development and severity of @entity137 degree and others improved the subjective symptoms ( @entity111 , pain, burning). Only @entity2636 dressings suggest effectiveness in all stages of @entity137 , in prevention, management of the different @entity137 degrees and improvement of wellbeing.
