Abnormal intrinsic brain activity patterns in XXXX with and without @entity73 .

@entity1 @entity73 @entity1274 @entity4365 @entity10334
UNASSIGNED: The @entity4365 ( @entity4365 ) from resting-state functional MRI (rs-fMRI) signals can be used to detect intrinsic spontaneous brain activity and provide valuable insights into the pathomechanism of @entity1274 . In this study, we recruited 56 @entity1 who had been diagnosed as having mild to severe @entity10334 . According to the neuropsychological tests, they were subdivided into a @entity10334 with @entity73 group (n=28) and a @entity10334 without @entity73 group (n=28). 28 volunteers were included as normal controls. We found that the three groups showed significant differences in @entity4365 in the brain regions of the right inferior occipital gyrus (IOG_R), left middle temporal gyrus (MTG_L), left precuneus (Pcu_L), right superior frontal gyrus (SFG_R) and right superior occipital gyrus (SOG_R). Compared with normal controls, the @entity10334 without @entity73 group exhibited significantly increased @entity4365 in the IOG_R, Pcu_L, SFG_R and SOG_R. While compared with @entity10334 without @entity73 group, the @entity10334 with @entity73 group showed significantly decreased @entity4365 in IOG_R, MTG_L, Pcu_L and SOG_R. A close negative correlation was found between the @entity4365 values of the MTG_L and the Montreal Cognitive Assessment (MoCA) scores. Our data demonstrate that white matter integrity and @entity73 are associated with different amplitude fluctuations of rs-fMRI signals. @entity10334 is related to @entity4365 increases in IOG_R, Pcu_L, SFG_Orb_R and SOG_R. @entity4365 in MTG_L is characteristic of @entity73 and may aid in its early detection.
