XXXX - where is the challenge?

@entity1 @entity788 @entity4929 @entity5409 @entity5 @entity189 @entity14775 @entity9007 @entity2513
@entity5409 of the pancreas are increasingly recognized due to the widespread use of modern abdominal imaging technologies. The majority of these lesions display @entity14775 . In contrast to @entity9007 , it is well established that mucinous @entity5 of the pancreas exhibit a significant potential for @entity5 over time. Among mucinous @entity5 , the most frequently observed entity is @entity788 ( @entity4929 ). IPMNs are characterized by cystic dilation of pancreatic ducts and the production of mucus and by an @entity2513 sequence eventually culminating in invasive @entity189 in some @entity1 . Due to the high risk of harboring malignancy, there is international consensus that IPMNs with involvement of the main pancreatic duct should be recommended for surgical resection. To date, the indication for surgery of branch-duct IPMNs is controversially discussed because of the overall lower risk of @entity5 compared to main-duct IPMNs. Particularly for small and asymptomatic side-branch IPMNs, the indication for surgical resection remains challenging. In addition to the international consensus guidelines, a number of potential preoperative features predicting @entity5 have been discussed recently. Moreover, novel surgical pancreatic parenchyma-sparing techniques such as enucleations or segmental pancreatic resections have been reported in order to treat IPMNs. The present article aims to demonstrate the current scientific knowledge in this field and to highlight the current controversy.    2014 S. Karger AG, Basel.
