The prognostic role of non-critical XXXX levels for in-hospital survival time among @entity341 @entity1 with @entity1850 .

@entity1 @entity341 @entity24604 @entity358 @entity880 @entity1850
OBJECTIVE: This study describes @entity341 ( @entity341 ) @entity1850 @entity1 with non-critical serum venous @entity880 ( @entity24604 ) levels ( @entity24604 <4.0 mmol/L) who suffered in-hospital mortality and examines @entity24604 in relation to survival times. METHODS: An @entity341 based retrospective cohort study accrued September 2010 to August 2014. Inclusion criteria were @entity341 admission, @entity24604 sampling, >2 @entity1850 ( @entity1850 ), and in-hospital mortality. Kaplan-Meier curves were used for survival estimates. An a priori sub-group analysis for @entity1 with repeat @entity24604 within 6 hours of initial sampling was undertaken. The primary outcome was time to in-hospital death evaluated using rank-sum tests and regression models. RESULTS: One hundred ninety-seven @entity1 met inclusion criteria. @entity358 were the most common (44%) and median @entity24604 was 1.9 mmol/L (1.5, 2.5). Thirteen @entity1 (7%) died within 24 hours and 79% by  <=28 days. Median survival was 11 days (95% CI, 8.0-13). Sixty-two @entity1 had repeat @entity24604 sampling with 14 (23%) and 48 (77%) having decreasing increasing levels, respectively. No significant differences were observed in treatment requirements between the @entity24604 subgroups. Among @entity1 with decreasing @entity24604 , median survival was 24 days (95% CI, 5-32). For @entity1 with increasing @entity24604 median survival was significantly shorter (7 days; 95% CI, 4-11, P = .04). @entity1 with increasing @entity24604 had a non-significant trend toward reduced survival (HR = 1.6 95% CI, 0.90-3.0, P = .10). CONCLUSIONS: In septic @entity341 @entity1 experiencing in-hospital death, non-critical serum venous @entity880 may be utilized as a risk-stratifying tool for early mortality, while increasing @entity24604 levels may identify those in danger of more rapid deterioration.
