[Antioxidant enzymes and lipid peroxidation products in XXXX with pulmonary tuberculosis].

@entity1 @entity2041 @entity2196 @entity358 @entity378 @entity224
INTRODUCTION: A lot of studies have dealt with the oxidative stress in @entity358 , and some of them with @entity378 as well. The aim of this study was to examine the antioxidant enzyme level ( @entity224 dismutase, @entity2041 peroxidase, @entity2196 ) and the lipid peroxidation products in @entity1 with @entity378 . MATERIAL AND METHODS: Forty @entity1 with @entity378 were included in the study. The examined parameters were measured before and three weeks after the beginning of the antituberculosis treatment (group I). The control group included 40 healthy @entity1 (group II). RESULTS: The @entity224 dismutase level was significantly lower in group I in both measurements (p < 0.001 and p < 0.01) in relation to group II, but there were no significant changes in its level during the therapy. During the treatment, the glutation peroxidase level significantly increased (p < 0.05), and in relation to group II, its level was significantly lower in both measurements in group I (p < 0.001 and p < 0.001). The @entity2196 level significantly increased during the treatment, but there was no significant difference in relation to group II level. There was no significant difference in relation to the lipid peroxidase products between the groups. DISCUSSION: Our study group had reduced antioxidant enzyme level and some of them showed significant improvement during the treatment. The lipid peroxidase product level was stable. CONCLUSION: In @entity1 with @entity378 the antioxidative status is lower and its level and possible development of the oxidative stress depend on the disease severity.
