Sequential changes in bone biochemical parameters and XXXX after renal transplant.

@entity1 @entity174 @entity2741 @entity5886 @entity79 @entity460 @entity1140 @entity3151 @entity2742 @entity560
UNASSIGNED: To evaluate sequential changes in biochemical bone parameters, parathyroid hormone (iPTH), @entity560 levels and @entity79 ( @entity79 ) over a period of 24 weeks after renal transplantation, we studied 75 @entity1 (58 males, with a mean age of 35.4 years) who underwent their first renal transplantation without a past history of parathyroid surgery or @entity174 . Serum @entity460 , @entity3151 and albumin were measured before transplant, then weekly for four weeks and monthly for the following 20 weeks. Serum iPTH and @entity560 levels and @entity79 were measured at baseline and 24 weeks after transplantation. After transplantation, there was a significant fall in serum @entity460 in the first week, followed by a gradual rise. At 12 and 24 weeks, respectively, 17.5% and 8% @entity1 had @entity2741 . Serum @entity3151 decreased after transplant and at 24 weeks; 25% @entity1 had @entity5886 . The iPTH levels declined significantly from 251    218.2 pg/mL before transplant to 97    142.8 pg/mL at the end of the study period. At 12 and 24 weeks, 42.7% and 51.3% @entity1 , respectively, @entity2742 ( @entity2742 ). Elevated baseline iPTH levels and graft dysfunction were the risk factors for @entity2742 at 12 weeks, while low @entity560 levels were the risk factor at 24 weeks. The @entity79 showed a significant decline of 2.7% after transplant, and it negatively correlated with the pre-transplant iPTH levels; the @entity1 who received @entity1140 immunosuppression had a lower decline in @entity79 than the rest of the @entity1 . No @entity174 were reported during the study period. We conclude that, after renal transplantation, @entity2741 and @entity5886 are common, while a significant proportion of @entity1 have persistent @entity2742 and decline in @entity79 .
