Bundled preparation of skin antisepsis decreases the risk of cardiac implantable electronic device-related XXXX .

@entity1 @entity5394 @entity4279 @entity281 @entity955 @entity299 @entity285
AIMS: To evaluate the efficacy of bundled skin antiseptic preparation to prevent @entity299 . METHODS AND RESULTS: From January 2010 to November 2013, 665 consecutive @entity1 were divided into two groups according to the strategy of skin preparation. In Period 1 (January 2010  to June 2012), 395 @entity1 received the standard skin antiseptic preparation. In @entity5394 (July 2012  to November 2013), 270 @entity1 received a triple-step skin antiseptic preparation, 'bundled skin antiseptic preparation', consisting of applying 75% @entity285 over anterior chest on the night before the index day, @entity4279 10 min before operation, and the standard skin antiseptic preparation before incision. During follow-up, the occurrence of @entity299 was recorded. Multiple logistic regression analysis was used to determinate the risk factors of @entity299 . During a mean follow-up of 26.9    16.2 months, 20 episodes of @entity299 developed in 19 @entity1 (2.9%), and the incidence of minor and major @entity281 episodes was 2.2% and 0.8%, respectively. @entity1 with the bundled skin antiseptic preparation had a significantly lower incidence of @entity299 , compared with @entity1 with the standard preparation (0.7 vs. 4.3%, P = 0.007). In multivariate analysis, pocket haematoma (P = 0.020), @entity955 (P = 0.033), and complex procedures (P = 0.047) were independent predictors for @entity299 . In contrast, the bundled skin antiseptic preparation was a significant predictor against @entity299 (P = 0.014). CONCLUSION: Pocket haematoma was the most important risk factor for @entity299 . The bundled skin antiseptic preparation strategy significantly reduced the risk of minor @entity299 .
