Induction of proinflammatory cytokines and @entity842 by XXXX in renal cells.

@entity8 @entity1527 @entity63 @entity19 @entity5 @entity1526 @entity281 @entity842 @entity810 @entity2401
@entity1526 is typically associated with cardiac involvement. During the acute phase of @entity19 @entity281 with @entity1527 , severe @entity2401 can develop. Prior to cardiac alteration, however, infected @entity19 present with @entity8 causing @entity810 due to an @entity63 /reperfusion lesion. Thus, the present study was undertaken in order to evaluate whether the parasites or some of their components would directly affect renal cells. As such, this study employed kidney cell lines (mesangial, epithelial, and proximal tubular) that mimic different regions of the renal system. Mesangial cells are more resistant to @entity281 , showing reduced parasite internalization relative to epithelial and proximal tubular cells. Upon @entity281 , mesangial cells produced more @entity842 , @entity5 factor necrosis-a, and interferon-y and showed decreased viability when compared to the other cell lines. These results indicate that the resistance of mesangial cells to @entity281 may be related to the increased expression of @entity842 and proinflammatory cytokines. Conversely, the high levels of @entity842 produced by these cells caused impairment of cell integrity and viability. Higher @entity842 concentrations promote cellular injury and can be involved in the genesis of @entity63 /reperfusion lesions in @entity810 .
