Prognostic value of myocardial perfusion imaging and coronary artery XXXX measurements in @entity1 with @entity454 .

@entity1 @entity583 @entity6 @entity1562 @entity460 @entity299 @entity453 @entity204 @entity454
OBJECTIVE: @entity453 ( @entity453 ) is highly prevalent in @entity1 with @entity454 ( @entity454 ), owing to clustering of traditional and uremic-specific risk factors. However, in this population asymptomatic course of @entity453 is common and it has been reported that myocardial perfusion imaging (MPI) with single-photon emission tomography (SPET) has lower sensitivity. In the current study, we assessed the value of MPI gated-SPET and its combination with coronary artery @entity460 (CAC) score measurements in risk stratification of @entity454 @entity1 . MATERIALS AND METHODS: MPI gated-SPET was performed with dual-headed SPET camera and CAC score measured by multi-detector computed tomography (MDCT) system.There were tested 77 @entity454 individuals. During the follow-up study, @entity299 ( @entity299 ) defined as @entity204 or nonfatal @entity583 ( @entity583 ) or the necessity for coronary revascularization were recorded. Univariate and stepwise multivariable Cox proportional hazards-models were used to identify the predictors of @entity299 . RESULTS: Eighteen @entity299 were recorded during the follow-up. They were significantly associated with higher summed stress scores on MPI, higher percentage of @entity1562 , higher occurrence of defects in multiple territories and higher CAC score (all with P<0.05). Univariate Cox proportional hazard-models showed that severe perfusion abnormalities as well as CAC score >= 1000 were significantly associated with @entity299 (P<0.0001, P=0.0056). In stepwise Cox proportional hazards-models considering age, gender, history of @entity6 , post-stress left ventricular stunning, the degree of perfusion abnormality and CAC score, only severe perfusion abnormalities and CAC score >= 1000 were independent predictors of @entity299 . There was no @entity299 in @entity1 with normal perfusion, normal function and zero CAC score. CONCLUSION: This study suggests that combined evaluation of MPI and CAC can predict the outcome in @entity454 individuals, while severe perfusion abnormality on gated-SPET and high CAC score >= 1000 are predictors of future @entity299 .
