XXXX : Detection, Characterization, and Clinical Correlates by Three-Dimensional Transesophageal Echocardiography.

@entity1 @entity1545 @entity66 @entity16 @entity1252 @entity149 @entity886 @entity887 @entity47
BACKGROUND: @entity1252 , characterized by Libman-Sacks @entity47 , is common in @entity1 with @entity1252 and is commonly complicated with @entity887 . Thus, accurate detection of Libman-Sacks @entity47 may lead to early therapy and prevention of their associated complications. Although two-dimensional (2D) transesophageal echocardiography (TEE) has high diagnostic value for detection of Libman-Sacks @entity47 , three-dimensional (3D) TEE may allow improved detection, characterization, and clinical correlations of Libman-Sacks @entity47 . METHODS: Twenty-nine @entity1 with @entity1252 (27 @entity1 ; mean age, 34      12  years) prospectively underwent 40 paired 3D and 2D transesophageal echocardiographic studies and assessment of @entity66 manifested as @entity16 , @entity149 , or focal @entity1545 on magnetic resonance imaging. Initial and repeat studies in @entity1 were intermixed in a blinded manner with paired studies from healthy controls, deidentified, coded, and independently interpreted by experienced observers unaware of @entity1 ' clinical and imaging data. RESULTS: The results of 3D TEE compared with 2D TEE were more often positive for mitral or @entity886 , and 3D TEE detected more @entity47 per study and determined larger sizes of @entity47 (P   <=  .03 for all). Also, 3D TEE detected more @entity47 on the anterior mitral leaflet, anterolateral and posteromedial scallops, and ventricular side or both atrial and ventricular sides of the leaflets (P  <  .05 for all). In addition, 3D TEE detected more @entity47 on the aortic valve left and noncoronary cusps, coronary cusps' tips and margins, and aortic side or both aortic and ventricular sides of the cusps (P   <=  .01 for all). Furthermore, 3D TEE more often detected associated mitral or aortic valve commissural fusion (P  = .002). Finally, 3D TEE detected more @entity47 in @entity1 with @entity66 (P  = .01). CONCLUSIONS: Three-dimensional TEE provides clinically relevant additive information that complements 2D TEE for the detection, characterization, and association with @entity66 of @entity1252 .
