[Catheter-directed thrombolysis of XXXX ].

@entity1 @entity548 @entity49 @entity1151 @entity1150 @entity2979 @entity715 @entity850 @entity1211 @entity1229
BACKGROUND: Although a success rate of 80% has been reported in @entity1 with @entity49 treated with catheter-based thrombolysis, the possible long-term benefit of this treatment is not known. MATERIAL AND METHOD: 28 consecutive @entity1 referred for catheter-based thrombolysis of @entity49 were treated with infusion of alteplase into the thrombus for two to five days. Following thrombolysis, @entity1229 was given for at least one year. All @entity1 were examined every six months with colour duplex scanning and air pletysmography. RESULTS: 100% thrombolysis was achieved in eight @entity1 , 75-99% in ten, 50-74% in nine and < 50% in one @entity1 . Angioplasty (four) or stent implantation (four) was successful in eight out of twelve @entity1 with @entity850 of the left common iliac vein. Early recurrence of @entity715 (< 7 days) occurred in three @entity1 , @entity1151 in one, and @entity548 at the insertion site in six. After a mean follow-up of 2.5 years, 17 @entity1 were free of symptoms, seven had a mild degree and four a moderate degree of @entity2979 . Eighteen @entity1 had normal venous physiology, nine deep @entity1211 , and three functional obstruction of deep veins. @entity2979 was associated with deep @entity1211 and/or functional obstruction of the iliofemoral segment. INTERPRETATION: Catheter-based thrombolysis is a safe and effective treatment of proximal @entity1150 and might reduce the occurrence of @entity2979 compared to treatment with anticoagulation alone.
