@entity159 in well-oxygenated @entity35 causes XXXX .

@entity410 @entity1249 @entity16711 @entity1188 @entity15945 @entity1251 @entity35 @entity528 @entity159
@entity528 in the brain resulting from @entity159 of 15 to 120 minutes duration in ventilated and well-oxygenated @entity35 was assessed. @entity410 were induced by inhalation of the convulsant gas @entity15945 , and terminated by withdrawal of @entity15945 and a single injection of thiopental. The animals were allowed to recover for one week, and neuronal damage was assessed by cell counts following subserial sectioning of the brain and microscopical examination of the sections. @entity1188 of the pars reticulata of the substantia nigra occurred in 5 of the 6 animals with @entity410 duration of 30 minutes, and in all animals with longer @entity410 durations. There also was a common affectation of the central parts of the globus pallidus. The pars compacta of the substantia nigra was never affected. After 45 to 120 minutes of @entity410 , moderate @entity528 was observed in the neocortex (layers 3 and 4), and after 60 to 120 minutes was seen in amygdaloid and thalamic nuclei, as well as in @entity16711 and @entity1249 hippocampal pyramidal cells. Notably, @entity1251 neurons were not damaged nor were dentate granule cells affected. After 120 minutes of @entity410 , damage regularly affected the neocortex and the ventral-posterior nuclei of the thalamus. A conspicuous feature was the localization of @entity528 at sites close to the ventricles.
