Cerebellum as Initial Site of Distant XXXX from Papillary Carcinoma of Thyroid: Review of Three Cases.

@entity1 @entity1276 @entity259 @entity3
Background. The cerebellum as initial site of distant @entity3 from differentiated @entity259 (DTC) including papillary (PTC) and @entity259 ( @entity259 ) is rare manifestation. Case Presentations. Herein, we present three cases of cerebellar @entity3 (CBM) of PTC. Mean age of @entity1 was 67 years (range: 64-72), and mean duration between initial diagnosis and CBM was 49.6 months (range: 37-61). Frequent location was left cerebellar hemisphere and was associated with @entity1276 . All @entity1 underwent suboccipital craniectomy, and in two @entity1 postoperative intensity modulated radiation therapy (IMRT) was given to deliver 5000   cGy in 25 fractions to residual lesions. @entity1 without postoperative IMRT had cerebellar recurrence along with lung and bone @entity3 after 38 months. However, two @entity1 were found alive and free of disease at the time of last follow-up. Conclusion. CBM from PTC is a rare clinical entity and is often associated with @entity1276 . Histopathological diagnosis is important to initiate effective treatment, which relies on multidisciplinary approach to prolong the disease-free and overall survival rates.
