Predictive ability of Charlson comorbidity index on outcomes from XXXX .

@entity1 @entity1149 @entity2 @entity151 @entity204
BACKGROUND: The effect of age and/or comorbidities on management decisions in @entity2 @entity1 has been debated. The Charlson Comorbidity Index (CCI) was developed to help predict mortality from chronic medical conditions. This study was undertaken to evaluate whether CCI is correlated with @entity2 . @entity1 AND METHODS: A retrospective chart review of 617 @entity2 @entity1 diagnosed between 1994 and 2007 was conducted. CCI was calculated for each @entity1 with and without the inclusion of age. Multivariate Cox proportional hazard regression analysis was used to evaluate the relationship between CCI and survival while adjusting for other prognostic factors. RESULTS: Six @entity1 were excluded from the final analysis due to missing outcome or comorbidity data. The median age at diagnosis was 64 years (range, 16-89 y). Five hundred fourteen @entity1 (84%) had @entity1149 and 97 @entity1 (16%) had @entity151 . Using multivariate analysis, no correlation was found between CCI and risk of @entity204 whether or not age was included in the index score. CONCLUSIONS: CCI did not provide predictive @entity2 @entity1 . Development of accurate and predictive prognostic models to help estimate a @entity1 's prognosis is needed.
