Retrospective study of conservation surgery for XXXX with or without axillary dissection.

@entity1 @entity797 @entity0 @entity3
BACKGROUND: It is already known that for @entity0 @entity1 , an axillary dissection or locoregional radiation has no major effect on survival with a simple mastectomy. We analyzed whether axillary dissection improved the prognosis for breast conservation surgery. METHODS: From 1982 to 1995, 31 @entity1 underwent axillary dissection and 33 did not in association with breast conservation surgery performed at our institution. Median follow up was at 55 months, ranging from 3 to 210. Survival rates of @entity1 were analyzed retrospectively. RESULTS: In the dissection group, 8 @entity1 had recurrence and 5 died within 3 years, yielding a relapse-free survival rate of 71%. In the non-dissection group, 7 @entity1 had recurrence, 3 died within 3 years, with a relapse-free survival rate of 79%. Figures for overall survival, relapse-free except breast and relapse-free for breast at 5 years were 93%, 73%, and 96% for the dissection group, and 93%, 89%, and 89% for the non-dissection group, respectively. No difference was found in survival rates between the two groups. Adjusted by @entity797 's regression analysis, survival rates of overall, relapse-free, relapse-free except breast and relapse-free for breast, at 5 years were 86%, 71%, 77%, and 90% for the dissection group, and 100%, 78%, 85%, and 95% for the non-dissection group, respectively. No survival benefit was found in axillary dissection. The first site of recurrence was in the affected breast in 3 @entity1 and in other sites in 5 @entity1 for the dissection group, while for the non-dissection group it was in the affected axilla in 1 @entity1 , the skin of the affected breast in 1 @entity1 , the affected breast in 3 @entity1 , and other sites in 2 @entity1 . In the non-dissection group, a @entity1 who had recurrence on the skin of the affected breast, subsequently had an axillary recurrence on the same side with plexus paresis. CONCLUSION: In breast conservation, prophylactic axillary dissection seems to be omitted, but the axilla of the affected side should be examined for @entity3 while treatment is possible.
