XXXX : a clinicopathological study of 34 @entity1 .

@entity1 @entity3852 @entity5 @entity3 @entity1349
BACKGROUND: @entity3852 ( @entity3852 ) is a rare cutaneous @entity5 . Its natural course is fast progression of the primary @entity5 and rapid regional metastasis. METHODS: The pathological archives of Helsinki University Hospital and Vaasa Central Hospital were reviewed from 1987 to 2001. Specimens were re-evaluated by two pathologists and size was measured from primary @entity5 . Multivariate analysis was performed for age, sex, primary @entity5 size, and method of initial surgery, development of @entity3 and development of local recurrence. @entity1349 ( @entity1349 ) was calculated by the Kaplan-Meier method. RESULTS: Of 34 @entity1 , 12 male and 22 female @entity1 , are reported. Their median age was 76.4 years. Half of the primaries were located in the head and neck region. All @entity1 were treated surgically. The mean @entity1349 was 2.7 years by the Kaplan-Meier method. The 2-year survival rate was 65% and 5-year rate was 50%. The mean @entity1349 for @entity5 size >2 cm was 1.7 years and for @entity5 size <or=2 cm 4.48. Poor prognostic factors for @entity1349 were: male sex, size of the primary @entity5 (>2 cm) and metastatic dissemination. A favourable prognosis seemed to correlate to more aggressive surgical management as use of primary excision with split skin graft or reconstruction with a local flap. CONCLUSION: @entity3852 affects the elderly @entity1 . In this study, female @entity1 predominated. Primary @entity5 size >2 cm predicts poorer outcome of the disease. A wide surgical excision is recommended for the primary treatment of @entity3852 .
