Treatment of XXXX in Bloemfontein, South Africa.

@entity1 @entity1143 @entity353 @entity5 @entity2615 @entity158
OBJECTIVE: Two different surgical methods for treating @entity2615 (pleurectomy and pleuro pneumonectomy) were reviewed. METHODS: This was a retrospective study from 1976 to 2001. Forty-six @entity1 , aged 35-80 years, received one of the following procedures: pleurectomy (n=29), or pleuro pneumonectomy (n=17). Pleurectomy was indicated in symptomatic @entity1 with @entity158 or @entity1143 while pleuro pneumonectomy was indicated in @entity1 with Butchart stage I or II disease and an acceptable cardiopulmonary reserve. @entity1 received either chemotherapy, radiation, or in combination after surgery. RESULTS: The mortality rate was 3.8% for pleurectomy @entity1 and 5.8% for pleuro pneumonectomy @entity1 . The median survival rate for pleurectomy @entity1 was 9 months, and 12 months for pleuro pneumonectomy @entity1 . Pleuro pneumonectomy @entity1 experienced less morbidity and had a shorter hospital stay than pleurectomy @entity1 . CONCLUSIONS: Improved survival was obtained with both procedures. Morbidity was higher in the @entity1 who underwent pleurectomy. Important prognostic factors include @entity5 stage, @entity5 histology, duration of symptoms, and @entity353 or @entity158 as a presenting symptom. @entity1 with a @entity5 stage, epithelial histology, absence of @entity158 or @entity353 , and a longer onset of symptoms had the best survival rate. A trend towards improved survival in @entity1 undergoing pleuro pneumonectomy and receiving radiation as adjuvant therapy was observed.
