Cochlear Implants as a Treatment Option for Unilateral Hearing Loss, Severe XXXX and @entity7804 .

@entity1 @entity7804 @entity1032 @entity8719 @entity392 @entity1274 @entity393 @entity2459
UNASSIGNED: @entity392 is an incapacitating condition commonly affecting cochlear implant (CI) candidates. The aim of this clinical study is to assess the long-term effects of CI treatment in @entity1 with severe-to-profound, sensorineural, @entity393 ( @entity393 ) and incapacitating @entity392 . We performed a prospective Cochlear    company-sponsored multicentre study in five Spanish centres. Sixteen @entity1 with @entity393 and incapacitating @entity392 , which was indicated by a @entity1032 Inventory (THI) score >58%, received a Nucleus   CI in their deaf ear. The study design includes repeated within-subject measures on hearing, @entity392 , @entity7804 and quality of life up to 12 months after initial CI fitting. In addition to @entity393 and @entity392 , all @entity1 suffered from @entity7804 . Most @entity1 had a @entity2459 and received a CI within 2 years after their @entity393 . Preliminary 6-month, post-CI activation data of 13 subjects showed that the majority of @entity1 perceived a subjective benefit from CI treatment, which was assessed using the THI, a Visual Analogue Scale of @entity392 loudness/annoyance and the Speech, Spatial and Qualities of Hearing Scale. Preliminary 12-month data of 7 subjects showed that most @entity1 also perceived a degree of relief from their @entity7804 . One @entity1 showed no improvements in any of the applied scales, which could be explained by partial insertion of the electrode due to obstruction of the cochlea by @entity8719 . In conclusion, CI can successfully be used in the treatment of @entity393 @entity1 with accompanying severe @entity392 and @entity7804 . Implantation resulted in hearing benefits and a durable relief from @entity392 and @entity7804 in the majority of @entity1 . These findings support the hypothesis that pathophysiological mechanisms after peripheral @entity1274 are at least partly reversible when hearing is restored with a CI.    2015 S. Karger AG, Basel.
