XXXX is associated with worse self-reported outcomes after kidney transplantation.

@entity1 @entity8 @entity908 @entity740 @entity810 @entity460 @entity1011 @entity3151 @entity7634
PURPOSE: We sought to determine the association between health-related quality of life (HRQOL) and graft function in renal transplant recipients. DESIGN AND METHODS: We enrolled 577 kidney transplant recipients aged 18-74 years (response rate 87%). Recipients with multiple or multi-organ transplantation, @entity908 kinase >200 U/L, @entity810 or cellular rejection (n = 64), and without @entity1011 assessments in 3 months pre-enrollment (n = 127) were excluded. The questionnaire included @entity7634 QOL 5 Dimensions (EQ-5D), Health Utility Index III (HUI-III), @entity8 Quality of Life-36 (KDQOL36) which include a generic section (RAND SF-12). Data on medical conditions, therapy regimens, and biochemistry results were extracted from clinical charts. We used general linear models adjusted for demographic, socioeconomic, and clinical characteristics to assess the association between HRQOL and severity of @entity740 ( @entity740 ). RESULTS: @entity1 with more advanced @entity740 were more likely to be African-American, covered by public insurance, more likely to have shorter time after transplantation, higher @entity3151 and lower hemoglobin, serum albumin, and @entity460 levels. All HRQOL scales were inversely associated with @entity740 severity. All associations were robust to adjustment for possible confounders. CONCLUSIONS: Several health-related quality of life dimensions may be affected by poor renal function after transplantation.
