Evaluation of non-surgical therapy on XXXX levels in @entity7278 .

@entity1 @entity9492 @entity7278 @entity2041 @entity6172
OBJECTIVE: To compare the levels of @entity2041 ( @entity6172 ), both oxidized and reduced forms in @entity1 with and without @entity7278 in gingival crevicular fluid (GCF). MATERIALS AND METHODS: Twenty GCF samples from maxillary quadrants were collected using capillary micropipettes from the @entity7278 @entity1 (test group) at baseline before treatment, at 1-month, 3 months, and 6 months after scaling and root planing and samples from 20 @entity1 without @entity7278 (control group) from maxillary quadrants were also collected. @entity6172 , @entity9492 ( @entity9492 ) levels and @entity6172 : @entity9492 ratios were determined using the spectrophotometric method. STATISTICAL ANALYSIS: Results were concluded for the test over control groups using paired Student's t-test. RESULTS: Lower concentrations of @entity6172 (P < 0.001) and @entity9492 (P < 0.001) were detected in GCF in @entity1 with @entity7278 (test group) than @entity1 without @entity7278 (control group) at baseline. Treatment had a significant effect in improving the @entity6172 and reducing @entity9492 levels postscaling and root planing at 1-month and 3 months but not significant effect at 6 months. Scaling and root planing increased the @entity6172 : @entity9492 ratio (P < 0.001) in the test group as compared to the control group (P < 0.001). CONCLUSIONS: The concentrations of @entity6172 within GCF are reduced in @entity7278 @entity1 . Scaling and root planing (nonsurgical therapy) restores @entity6172 concentration in GCF post 1-month and 3 months along with redox balance ( @entity6172 : @entity9492 ratio), but at 6 months the balance is not maintained. Adjunctive use of micronutritional supplements to boost antioxidant concentration in tissues by preserving @entity6172 or by elevating its level at the inflamed sites is recommended, as nonsurgical periodontal therapy alone is not able to maintain redox balance for longer duration.
