Clinical Characteristics, Management, and Outcomes of Acute Coronary Syndrome in XXXX With Right Bundle Branch Block on Presentation.

@entity1 @entity1187 @entity714 @entity299 @entity65
UNASSIGNED: We examined the relations between @entity714 ( @entity714 ) and clinical characteristics, management, and outcomes among a broad spectrum of @entity1 with @entity1187 ( @entity1187 ). Admission electrocardiograms of @entity1 enrolled in the Global Registry of Acute Coronary Events (GRACE) electrocardiogram substudy and the Canadian @entity1187 Registry I were analyzed independently at a blinded core laboratory. We performed multivariable logistic regression analysis to assess the independent prognostic significance of admission @entity714 on in-hospital and 6-month mortality. Of 11,830 eligible @entity1 with @entity1187 (mean age 65; 66% non-ST-elevation @entity1187 ), 5% had @entity714 . @entity714 on admission was associated with older age, male sex, more cardiovascular risk factors, worse Killip class, and higher GRACE risk score (all p <0.01). @entity1 with @entity714 less frequently received in-hospital cardiac catheterization, coronary revascularization, or reperfusion therapy (all p <0.05). The @entity714 group had higher unadjusted in-hospital (8.8% vs 3.8%, p  <0.001) and 6-month mortality rates (15.1% vs 7.6%, p <0.001). After adjusting for established prognostic factors in the GRACE risk score, @entity714 was a significant independent predictor of in-hospital death (odds ratio 1.45, 95% CI 1.02 to 2.07, p  = 0.039), but not cumulative 6-month mortality (odds ratio 1.29, 95% CI 0.95 to 1.74, p  = 0.098). There was no significant interaction between @entity714 and the type of @entity1187 for either in-hospital or 6-month mortality (both p >0.50). In conclusion, across a spectrum of @entity1187 , @entity714 was associated with preexisting @entity65 , high-risk clinical features, fewer @entity299 , and worse unadjusted outcomes. After adjusting for components of the GRACE risk score, @entity714 was a significant independent predictor of early mortality.
