Mild XXXX signs in a community-dwelling elderly population sample in Japan.

@entity1 @entity308 @entity191 @entity400 @entity179
Mild @entity191 signs (MPS) may represent the mild end of a disease spectrum that spans from normal aging to @entity179 . We conducted a population-based study in a rural island town in western Japan, Ama-cho. @entity1 included 1129 subjects, aged 60 years and older, residing in the town. @entity1 were classified according to a modified Unified @entity191 Rating Scale (mUPDRS) score. MPS was determined to be present if any of the following conditions were met: (1) two or more mUPDRS ratings=1 [MPS-mild]; (2) one mUPDRS rating>= 2; or (3) mUPDRS rest @entity400 rating>= 1; [(2) and (3): MPS-severe]. Subjects wore a uniaxial accelerometer (Actiwatch), resulting in the measurement of actigraphic activity counts (AC). Of the 804 @entity1 with complete data, 178 subjects (22.1%) were classified as demonstrating MPS. AC was significantly lower in the MPS-severe group compared with both the CTL and the MPS-mild groups. Diagnostic sensitivity for MPS-severe became 100% when we adopted a cutoff point of low physical activity, as measured by actigraphy, combined with the presence of subjective @entity308 . We established the prevalence of MPS in a community-dwelling elderly population sample in Japan. Actigraphy may be a useful objective tool for screening MPS-severe.
