[Low dosage radiotherapy of subfoveal neovascularization in age-related XXXX . Preliminary results].

@entity1 @entity1020 @entity3194 @entity941
AIM OF THE STUDY: The aim of this study is to test the effect of low dose radiation on the subfoveal neovascular membranes (SNVM) and to analyse visual acuity in age-related @entity1020 . METHODS AND @entity1 : From November 1993 through to August 1994, 10 @entity1 , on the one hand, were given a dose of 5 Gy followed by controls 6 weeks and 6 months later. On the other hand, 21 @entity1 were treated with a dose of 8 Gy and were subjected to controls 6 weeks later. Before the radiotherapy and during the control sessions, all @entity1 were required to be measured for different parameters of visual acuity and to receive a simultaneous @entity941 and @entity3194 angiography. The radiotherapy was done by a linear accelerator 6 MeV and through a lateral port 3 x 4 cm in half beam technic. RESULTS: In the 5 Gy group, no changes in the parameters for visual acuity were noted in most cases after 6 months. In 9 of the cases, the membranes had increased in size and in 1 case, they had remained unchanged. In the 8 Gy group, no changes in the visual acuity or in the membrane size were diagnosed. Of all the @entity1 treated, only one refused the angiography control. DISCUSSION AND CONCLUSIONS: Given the low dose used and the period of observation, the visual acuity of all @entity1 remained stable. The size of the membranes increased in most cases for those 5 Gy @entity1 and in this respect, no changes at all were noted in the 8 Gy @entity1 . In order to better evaluate the potential of radiotherapy, this study must be pursued and coupled with further studies analysing the effect of different doses on @entity1 .
