Stratification and symptom characteristics of XXXX based on acid and duodenogastroesophageal reflux.

@entity1 @entity662 @entity648 @entity344 @entity354
BACKGROUND AND AIM: The subgroups and symptom characteristics of @entity354 ( @entity354 ) based on acid and duodenogastroesophageal reflux may be different in Chinese @entity1 to Western @entity1 . This study aimed to explore the stratification and symptom characteristics of @entity1 with @entity354 . METHODS: @entity1 with typical heartburn and/or acid regurgitation symptoms were enrolled. Each @entity1 filled out a questionnaire. An upper gastrointestinal endoscopy was performed for each @entity1 followed by simultaneous ambulatory 24-h esophageal pH and Bilitec ( @entity648 ) monitoring. A symptom index (SI) of > or =50% was considered to be positive. RESULTS: Eighty-two consecutive @entity354 @entity1 were evaluated. Abnormal ( @entity354 pH+) and normal ( @entity354 pH-) 24-h pH tests were found in 24 (29.3%) and 58 (70.7%) @entity1 , respectively. Among 42 @entity354 pH- @entity1 who reported heartburn symptoms during monitoring, SI was positive in 19 (45.2%) @entity1 (NE-SI+) and negative in 23 (54.8%) @entity1 (NE-SI-). Pathological duodenogastroesophageal reflux (DGER) was found in 43 (52.4%) @entity1 . No significant differences were noted regarding the prevalence of other @entity344 , except for acid regurgitation in @entity354 pH+ and @entity354 pH- groups. Additionally, no significant differences were seen in the prevalence of other symptoms, except for @entity662 , in groups with pathological and normal DGER. CONCLUSION: The proportion of @entity354 @entity1 with pathological acid reflux was somewhat lower than that reported in Western countries. The role of DGER in @entity354 may be important. It is difficult to differentiate whether @entity354 @entity1 have pathological acid or bile reflux according to symptoms.
