Prognostic value of multi-detector computed tomography in asymptomatic XXXX .

@entity1 @entity1164 @entity9689 @entity7874 @entity9012 @entity453 @entity472
BACKGROUND: @entity9689 ( @entity9689 ) is a high-resolution imaging technique with potential additive value in the evaluation of @entity1 with @entity472 ( @entity472 ). We aimed to assess the prognostic value of @entity9689 in asymptomatic @entity1 with @entity472 compared to conventional transthoracic echocardiography (TTE). METHODS: 116 @entity1 with asymptomatic @entity472 (Vmax>2.5m/s assessed by clinical screening TTE, LVEF>50%) were examined with TTE (Vivid e9) and @entity9689 (Aquilion 320) on the same day. The treating physician was blinded for research protocol defined imaging results. Outcome was defined as indication for aortic valve replacement (AVR) determined by the treating physician or @entity1164 . RESULTS: The mean age was 72 (8) years, 27% were @entity1 , mean AVA by TTE was 1.01 (0.30) cm(2). Median follow up time was 27 (IQR 19-44) months. Forty seven @entity1 (41%) developed indication for AVR. No @entity1 suffered a @entity1164 . AVA and @entity7874 were significant univariable predictors of AVR when measured by both TTE and @entity9689 , whereas left ventricular mass was only significant measured by @entity9689 . Significant @entity453 by @entity9689 tended to predict future indication for AVR, but this did not reach statistical significance (HR: 1.79 (95% CI 0.96-3.44), p=0.08). CONCLUSION: @entity9689 derived AVA can be of use as an alternative to TTE derived @entity9012 in @entity1 with asymptomatic @entity472 to predict future clinical indication for AVR.
