Case-control XXXX mortality study and chlorination of drinking water in Louisiana.

@entity0 @entity96 @entity5 @entity1313 @entity694 @entity1582 @entity1778 @entity358 @entity150 @entity1893 @entity978 @entity204 @entity320 @entity703
Several Louisiana parishes (counties) using the Mississippi River for their source of public drinking water have the highest mortality rates (1950-69) in the United States for several @entity5 . Therefore, a case-control mortality study on @entity96 , brain, pancreas, bladder, kidney, prostate, rectum, colon, esophagus, stomach, @entity1893 , @entity1582 , @entity1778 , @entity978 , @entity358 ; breast and malignant @entity320 , from 1960 to 1975 in South Louisiana parishes grouped for similarities in industrial characteristics, having approximately equal exposure of the population to surface and groundwater, was conducted. Noncancer @entity204 were randomly selected as controls and matched to the case @entity204 on age, race, sex, and year and parish group of @entity204 . Water source at @entity204 was assigned based on the residence at @entity204 and described as surface or ground and chlorinated or nonchlorinated. A significantly increased risk for surface, chlorinated water use was noted for @entity5 . No risk could be demonstrated for @entity694 . The risk noted for @entity150 by other investigators is not substantiated. @entity1313 risk appears to be associated with chlorinated groundwater, but this may be industrial confounding. @entity0 demonstrated a slight, but significant, risk associated with surface chlorinated water. This risk, however, might be due to confounding of rural life style, early childbearing and large families with nonchlorinated water found in these settings. Chlorination risk for @entity703 was not significant. No risk was observed in association with surface water for other @entity5 of the gastrointestinal or urinary tract. @entity1582 was significantly associated with a risk from ground water.
