Atopy and anaphylactic reactions to XXXX .

@entity1 @entity1097 @entity402 @entity56 @entity2900
Muscle relaxants are widely used for general anesthesia and may be responsible for IgE-dependent anaphylactic reactions (AR). A controversial issue in the field of @entity56 is whether ARs are more frequent or severe in @entity1097 subjects. Thus, we performed a case-control study comparing the distribution of various clinical and biologic signs of @entity402 . The case group included 32 @entity1 with a history of AR to @entity2900 , the most commonly used muscle relaxant. The control group included 128 subjects, matched to the case group according to age, gender, and socioeconomic status. The case group consisted mainly of young and middle-aged @entity1 . Distribution of symptoms suggestive of @entity402 and of skin tests and specific IgE to common aeroallergens was similar in both groups. In contrast, total serum IgE level was much higher in the case group, suggesting the presence of specific IgE against @entity2900 or other drugs. Thus, despite previous studies in the literature, @entity402 is not a risk factor for the occurrence of anaphylactic reactions to muscle relaxants. As AR to @entity2900 is a pure model of an IgE-dependent @entity56 , our data do not support a relationship between @entity402 and @entity56 .
