Interstitial Fluid Colloid Osmotic Pressure in Healthy XXXX .

@entity1 @entity551
OBJECTIVE: The @entity551 ( @entity551 ) of plasma and interstitial fluid play important roles in transvascular fluid exchange. @entity551 values for monitoring fluid balance in healthy and sick @entity1 have not been established. This study set out to determine reference values of @entity551 in healthy @entity1 . MATERIALS AND METHODS: @entity551 in plasma and interstitial fluid harvested from nylon wicks was measured in 99 healthy @entity1 from 2 to 10 years of age. Nylon wicks were implanted subcutaneously in arm and leg while @entity1 were sedated and intubated during a minor surgical procedure. @entity551 was analyzed in a colloid osmometer designed for small fluid samples. RESULTS: The mean plasma @entity551 in all @entity1 was 25.6    3.3 mmHg. Arbitrary division of @entity1 in four different age groups, showed no significant difference in plasma or interstitial fluid @entity551 values for @entity1 less than 8 years, whereas @entity1 of 8-10 years had significant higher @entity551 both in plasma and interstitial fluid. There were no gender difference or correlation between @entity551 in interstitial fluid sampled from arm and leg and no significant effect on interstitial @entity551 of gravity. Prolonged implantation time did not affect interstitial @entity551 . CONCLUSION: Plasma and interstitial @entity551 in healthy @entity1 are comparable to adults and @entity551 seems to increase with age in @entity1 . Knowledge of the interaction between colloid osmotic forces can be helpful in diseases associated with fluid imbalance and may be crucial in deciding different fluid treatment options. TRIAL REGISTRATION: ClinicalTrials.gov NCT01044641.
