@entity5545 and voxel-based morphometry: correlations between five behavioural measures of XXXX and gray and white matter volumes.

@entity62 @entity3257 @entity5545
UNASSIGNED: In voxel-based morphometry studies of @entity5545 , the relation between causal theories of @entity5545 and @entity62 (WM) volume alterations is still under debate. Some alterations are consistently reported, but others failed to reach significance. We investigated @entity62 alterations in a large sample of Dutch students (37 dyslexics and 57 @entity3257 ) with two analyses: group differences in local @entity62 and total @entity62 and WM volume and correlations between @entity62 and WM volumes and five behavioural measures. We found no significant group differences after corrections for multiple comparisons although total WM volume was lower in the group of dyslexics when age was partialled out. We presented an overview of uncorrected clusters of voxels (p   <   0.05, cluster size k   >   200) with reduced or increased @entity62 volume. We found four significant correlations between factors of @entity5545 representing various behavioural measures and the clusters found in the first analysis. In the whole sample, a factor related to performances in spelling correlated negatively with @entity62 volume in the left posterior cerebellum. Within the group of dyslexics, a factor related to performances in Dutch-English rhyme words correlated positively with @entity62 volume in the left and right caudate nucleus and negatively with increased total WM volume. Most of our findings were in accordance with previous reports. A relatively new finding was the involvement of the caudate nucleus. We confirmed the multiple cognitive nature of @entity5545 and suggested that experience greatly influences anatomical alterations depending on various subtypes of @entity5545 , especially in a student sample.
