Body build from birth to adulthood and risk of XXXX .

@entity565 @entity15591 @entity46693 @entity28
BACKGROUND: Few reports aimed at the study of adulthood @entity28 and @entity565 have taken into account the effects of size at birth and @entity28 in adolescence. This paper examines the combined effect of size at birth and @entity28 in both adolescence and adulthood on the risk of @entity565 at age 31 years. METHODS: The study was derived from a prospectively population-based Finnish birth cohort born in 1966, for which data were collected in pregnancy and at various ages. Adulthood doctor-diagnosed @entity565 with current symptoms and results of skin prick tests were obtained in 1997. The analysis was limited to 4719 subjects with complete information on @entity565 and atopy and anthropometric measures at various ages. RESULTS: Ponderal index at birth had a U-shaped association with adult atopy, OR 1.30 (95% CI: 1.11-1.52) for the lowest tertile and @entity46693 (95% CI: 1.13-1.55) for the highest tertile, as compared to the middle tertile. The association was independent of @entity28 later in life. Those @entity28 (BMI > or = 95th percentile) in adolescence (OR 2.09, 95% CI: 1.23-3.57) and in adulthood ( @entity15591 , 95% CI: 1.14-3.47) had a higher occurrence of adult @entity565 than those with BMI < 85th percentile. Both estimates were reduced after mutual adjustment. CONCLUSIONS: Size at birth has a long-lasting effect on atopy in adulthood, which is independent of weight in adolescence and adulthood. Those who were @entity28 in adolescence and adulthood tended to have a higher risk of @entity565 in adulthood. These findings underline the importance of considering the life course of @entity28 in the analyses of @entity565 and atopy.
