Fundus autofluorescence of elongated photoreceptor outer segments in XXXX .

@entity1 @entity11471 @entity1713 @entity989
PURPOSE: To determine the origin of fundus autofluorescence (AF) patterns in @entity989 ( @entity989 ). DESIGN: Retrospective, observational case series. METHODS: We retrospectively studied 30 consecutive eyes of 30 @entity1 with primary @entity989 using AF and spectral-domain optical coherence tomography (SD-OCT). We measured the AF using the Heidelberg Retina Angiograph with a 488-nm excitation light and a 500-nm cutoff barrier filter and compared the AF patterns with ophthalmoscopy and SD-OCT. RESULTS: We observed a patchy increased AF in the macular area in 22 eyes (73%), in which the length of the photoreceptor outer segment at the central fovea tended to be longer than the other eyes (P=.06). The punctate increased AF corresponded to the ophthalmoscopic precipitates in 17 eyes with precipitates. AF significantly (P=.017) decreased in eyes with a @entity1713 ( @entity1713 ). Eight eyes (27%) had increased AF in the inferior @entity1713 . CONCLUSIONS: The patchy increased AF appears to originate from elongated photoreceptor outer segments in the @entity11471 . The autofluorescent fluorophores from the photoreceptor outer segments may be concentrated in precipitates or have settled into the inferior @entity1713 .
