A new @entity1020 with anomalous vascular development, @entity2118 , cystic spaces, and XXXX .

@entity1 @entity8721 @entity1940 @entity548 @entity2295 @entity2118 @entity941 @entity989 @entity1020 @entity4457
OBJECTIVE: To clinically phenotype an inherited @entity1020 with peculiar intraretinal @entity2118 , cysts, and @entity548 in a 24-year-old female proband and her family. METHODS: Extended family members of the proband underwent dilated fundus examination, optical coherence tomography, and, in selected cases, @entity941 angiography and electroretinography. RESULTS: Seventeen family members, representing 3 generations and ranging in age from 5 to 64 years, were clinically examined. Visual acuities ranged from 20/20 to 20/200. @entity4457 and strabismus were frequently present in affected individuals. Consistent with an autosomal dominant pattern of inheritance, 7 family members had multiple central macular cystic spaces and flat, round, densely @entity2118 . There were right-angle vessels and @entity8721 in the central macula. Two subjects showed evidence of active macular @entity2295 with leakage on @entity941 angiography at ages 7 and 24 years, which was responsive to either focal laser or a single injection of bevacizumab. In those cases examined, multifocal electroretinography showed a diminished foveal response. CONCLUSIONS: This spotted @entity1020 appears to represent a new @entity989 . Because these @entity1 are at risk for @entity1940 , identification of the responsible gene may provide insight into the mechanisms of pathological @entity2295 .
