Immunohistochemistry of XXXX and vasa vasorum.

@entity1 @entity64 @entity63 @entity1711 @entity1710 @entity1856 @entity543 @entity121 @entity204
Carotid artery surgical specimens from 15 consecutive @entity1 undergoing carotid endarterectomy were studied in an attempt to identify morphologic differences between carotid @entity543 (NV) and normal vasa vasorum (VV). The @entity1 included 12 @entity1 and 3 @entity1 with an age range of 55-81 years (mean, 67). Nine of them had @entity63 symptoms directly related to the plaque being removed. The specimens were stained with @entity1710 - @entity1711 , Verhoef-Van Gieson, and factor VIII-related antigen techniques. In addition, normal carotid arteries were obtained for comparison from two autopsies of young individuals, victims of @entity204 . The severity of NV within the plaque was graded based on the appearance and location of new vessels, as they compared to W. Mild NV (Grade I) was found in 3/15, whereas moderate and severe (Grades II and III) were each found in 6/15 cases. Increasing severity of NV was associated with more tortuosity, thicker walls, and location closer to the carotid lumen. The presence and severity of NV did not correlate with @entity121 (p = 0.2), the presence of symptoms (p = 0.5), or any other risk factors for @entity64 . Carotid plaque NV seems independent of the degree of @entity1856 and morphologically different than VV. Its origin, true incidence, and role in the production of carotid intraplaque hemorrhage and @entity64 risk are still uncertain. This is the first immunohistochemical study of @entity543 .
