Effect of a @entity691 -lined administration set on the availability of XXXX injection.

@entity691 @entity3175 @entity2634 @entity2827 @entity413
Delivery of @entity3175 through a @entity691 -lined i.v. administration set and through a @entity2634 ( @entity2634 ) set was compared. @entity3175 was prepared in concentrations of 50 mg/500 mL and 100 mg/500 mL in 0.9% @entity2827 injection and 5% @entity413 injection in glass containers. @entity3175 concentrations were measured by high-performance liquid chromatography at 0 through 5 hours in samples collected simultaneously from the glass solution containers and from the distal ends of a @entity2634 administration set and a @entity691 -lined (non- @entity2634 ) set. Flow rates of 50 and 100 mL/hr were tested. For the non- @entity2634 sets, @entity3175 concentration in the infusate was not significantly different from concentration in the glass container at any sampling time. The overall percentage of @entity3175 recovered was 100.7 +/- 6.8%. For the @entity2634 sets, @entity3175 concentration in the infusate was less than in the container at all sampling times, and the overall percentage of @entity3175 recovered was 65.4 +/- 13.3% (significantly different from delivery for the non- @entity2634 sets). Delivery through the non- @entity2634 sets was not affected by flow rate, type of solution, or concentration of @entity3175 . For infusion periods of up to five hours, delivery of @entity3175 through @entity691 -lined i.v. administration sets was superior to delivery through @entity2634 sets.
