XXXX in Tunisia (Monastir, Mahdia, 2011-2013): identification of virus variants cocirculating in France.

@entity1 @entity5827 @entity693
UNASSIGNED: Acute enterovirus (EV) @entity693 is a frequent cause of hospitalisation, and over 100 EV serotypes may be involved. A total of 215 @entity1 of all ages with @entity693 signs were investigated in 2 Tunisian hospitals. Their cerebrospinal fluid (CSF) was analysed retrospectively for EVs with a TaqMan real-time RT-qPCR. The virus strains were typed, and their evolutionary relationships were determined by Bayesian phylogenetic methods. An EV genome was detected in 21/215 @entity1 (9.8%). The CSF viral loads ranged from 3.27 to 5.63 log10 genome copies/mL. The strains were identified in 13/21 @entity1 and assigned to EV-B types. Viruses identified in Tunisian @entity1 were genetically related to variants detected in France. The viral loads were similar in Tunisian and French @entity1 for most EV types. The phylogenetic data and viral loads determined in Tunisian and French @entity1 suggest that close EV variants were involved in @entity5827 in the 2 countries over a same period.
