Malignant transformation of XXXX : a diagnostic pitfall.

@entity1 @entity0 @entity189 @entity652 @entity420
We present what is believed to be the first report of @entity189 arising from @entity0 . A 57-year-old @entity1 presented with a nodule in her right breast. Histological examination of a vacuum-assisted biopsy specimen revealed epithelial tubular proliferation and papillary apocrine epithelium. The myoepithelial cells lining the tubules were confirmed by immunohistochemistry. The nodule had increased in size 18 months later and tumorectomy was performed. The surgical specimen revealed proliferating apocrine epithelium with sheet-like and cribriform architecture within a mammary duct. Some myoepithelial cells showed irregular proliferation around the tubular epithelium. All three components, including apocrine, myoepithelial and glandular cells, showed prominent nuclear atypia and significant mitotic activity. The @entity1 was diagnosed with @entity420 . The malignant potential of ductal adenoma has not previously been discussed, but this @entity189 could represent a serious pitfall in the diagnosis of ductal @entity652 .
