[Diagnosis value of 3.0 T diffusion-weighted imaging with background suppression magnetic resonance for metastatic lymph nodes in XXXX ].

@entity5 @entity1 @entity3 @entity1162
OBJECTIVE: To evaluate the diagnostic value of 3.0 T diffusion-weighted imaging with background suppression (DWIBS) magnetic resonance (MR) for lymph node @entity3 in @entity5 . METHODS: Thirty-five @entity1 with @entity5 who underwent preoperative routine MRI+DWI examination were enrolled in the study and were treated by @entity5 resection plus lymph node dissection. Metastatic and non-metastatic lymph nodes were confirmed by postoperative pathology. Apparent diffusion coefficient (ADC) values, @entity1162 and short-axis diameters of lymph nodes were measured. Receiver operating characteristic (ROC) curve was used to assess the diagnostic efficacy of ADC, @entity1162 and short-axis diameters for differentiating metastatic lymph nodes from non-metastatic lymph nodes. RESULTS: A total of 151 lymph nodes were confirmed with exact location in 35 @entity1 . Sixty-five metastatic lymph nodes and 86 non-metastatic lymph nodes were identified. The ADC values of metastatic lymph nodes and non-metastatic lymph nodes were(0.86  0.14) 10(-3) and (0.94  0.16) 10(-3) mm(2)/s respectively. The @entity1162 diameter were(9.78  3.13) and (7.90  1.77) mm, respectively. The short-axis diameter were (7.65  2.00) and (6.45  1.19) mm, respectively. There were statistically significant differences between metastatic and non-metastatic lymph nodes in ADC values, @entity1162 diameter, and short-axis diameter(all P<0.01). The areas under the ROC curve of ADC value, @entity1162 diameter, and short-axis diameter were 0.648, 0.706, and 0.692, respectively. Optimal cutoff values for these parameters were 1.05 10(-3) mm(2)/s, 7.95 mm, and 5.90 mm, respectively, and the corresponding sensitivities and specificities were 93.8% and 30.2%, 75.4% and 61.6%, 90.8% and 38.4%. CONCLUSIONS: Quantitative measurement of ADC value may reflect the degree of diffusion restriction of metastatic lymph nodes by DWIBS at 3.0 T MR. Accurate diagnosis of metastatic lymph nodes in @entity5 demands comprehensive evaluation combining ADC value with diameter measurement.
