XXXX in @entity0 - first experience.

@entity1 @entity1136 @entity0 @entity5 @entity1600
(Full text is available at http://www.manu.edu.mk/prilozi). INTRODUCTION: @entity0 accouns for 22.9% of all @entity5 in @entity1 and 13.7% of @entity5 deaths. Positive axillary lymphnodes (ALN) predict the development of distant metastases. The status of the sentinel lymphnode (SLN) is crutial for the treatment selection. AIM: To determine the benefits of SLN detection in @entity1 with @entity0 . MATERIAL AND METHODOLOGY: 38 female @entity1 (pts), age 44    12 years, with T1-2 N0 M0 @entity0 , without enlarged ALN on ultrasound (US), were included. SLN detection was performed using gamma camera and gamma detection probe after periareolar subcutaneous and/or peritumoral injection of ( @entity1136 -SENTISCINT). Blue dye was administered 20 min before the operation. SLN was extirpated and ex tempore histopathology was performed. RESULTS: Ex tempore SLN evaluation was negative and the lymphatic pathways preserved in 28/38 (74%) pts. In 10/38 (26%) pts SLN was positive, followed by radical surgery. In 3/28 ex tempore negative @entity1 , histopathological analysis showed metastatic involvement (false negative). In 3/10 ex tempore positive @entity1 micro metastases 0,2-2 mm were detected. 12 pts had 2 SLN, 8/12 (66%) had negative and 4/12 (34%) had positive SLN. 3 pts had a rare double drainage to axilla and a. mammaria int. CONCLUSION: Our results confirm that SLN detection technique is non-invasive, safe and reliable and should be incorporated into the guidelines for @entity0 pts (T1-2 N0 M0). The most reliable option for colloid application is the combined technique of periareolar and peritumoral injection. @entity1 with drainage to a. mammaria interna should be selected for adjuvant protocols. Key words: @entity0 , @entity1600 .
