Behavioral effects evoked by @entity2344 and XXXX in adult @entity468 .

@entity384 @entity3828 @entity1833 @entity3826 @entity468 @entity2344
The aim of the present work was to study the behavioral effects elicited in adult @entity468 by the selective D1 agonist, @entity2344 , and the D2 agonist, @entity3828 , comparing their effects with those evoked by @entity3826 . In 10 adult @entity468 , 0.5, 1.0, 4.0, and 8.0 mg/kg IP of @entity2344 were administered at random. A dose-response effect was observed related to alertness, indifference, and locomotion. The overall effect of @entity2344 was inhibitory. To the same 10 animals, @entity3828 in doses of 0.25, 0.5, and 1.0 mg/kg were injected IP. This drug had an excitatory and more complex effect than what was observed with the D1 agonist. Increases in locomotion, in alertness, indifference, fear, olfaction, @entity384 , @entity1833 , limb flicking, and head shaking were recorded. @entity3826 given to the same @entity468 , in a dose equimolar to 1.0 mg/kg of @entity3828 , elicited behaviors that resembled those elicited by the latter drug, but of a lesser intensity and duration. The interval between the different treatments was approximately 2 months. These results show clearly that the D2 receptor is the main dopaminergic receptor involved in the mechanism of production of most of the behavioral effects produced by some of the dopaminergic agonist drugs like @entity3826 .
