Surgery alone or combined with radiation therapy in XXXX .

@entity1 @entity5 @entity418 @entity3
Two @entity1 -materials with @entity418 are analyzed: a group of 22 @entity1 who, during the period 1971-1974, were treated with esophageal resection followed by esophagogastrostomy or colonic interpolation; a second group of 28 @entity1 from 1975-1978, who were treated in the same way, but also given either preoperative or postoperative radiation therapy, or both. Surgical mortality was about the same in the two groups: 25-32%. The group given radiation therapy had a one-year survival rate of 50%, as compared with 23% in the group treated solely with surgery. All 24 @entity1 given combined therapy, with all or part of the absorbed dose of 24-47 Gy given preoperatively, showed @entity5 in resected specimens. @entity5 was found in the periesophageal nodes in only six @entity1 (25%), however; @entity1 given no preoperative radiation therapy had @entity5 in 20 of 26 cases (77%; P less than 0.01). Celiac nodes were resected at laparotomy; when @entity5 was found, the celiac region was irradiated postoperatively. This finding does not appear to exclude long-term survival, as two @entity1 with @entity3 to the celiac nodes at operation are alive 16 and 20.5 months following surgery. Simple compared to troublesome dissection gives a better rate of survival. The spleen was unintentionally injured in 21 @entity1 at laparotomy and had to be removed. One-year survival was better in @entity1 with intact spleen, especially in those who also had radiation therapy. @entity1 with resected spleen succumbed from @entity3 more often than from mediastinal recurrence, as compared with the @entity1 with intact spleen.
