Haemodynamic adaptation during exercise in fontan XXXX at a long-term follow-up.

@entity1 @entity26 @entity64 @entity998
OBJECTIVE: To assess the haemodynamic regulation at rest and during exercise in Fontan @entity1 at a long-term follow-up. DESIGN: Cardiac output was measured with the dye-dilution technique. We examined 15 out of the surviving 20 @entity1 operated upon in G  teborg between 1980 and 1991. Their mean age was 26.4 years. Four @entity1 had to be excluded due to technical reasons. RESULTS: Median maximal @entity26 uptake was 1.47 l/min, corresponding to 21.9 ml/kg/min. Cardiac output was lower than expected at all exercise levels, presumably due to a reduced pulmonary blood flow. The median maximal cardiac output value was 8.0 l/min. @entity64 volume index was 33 ml/m (2). The subjects compensated for the @entity998 with an increased arteriovenous @entity26 difference. They had a normal increase in arterial blood pressure. This was achieved by an increase in total peripheral resistance. CONCLUSION: The low maximal exercise capacity was due to a @entity998 and a reduced pulmonary blood flow. This was compensated for by an increased arteriovenous @entity26 difference
