Efficacy of stannous, XXXX and their their combination in dentin @entity2681 prevention in vitro.

@entity1 @entity18360 @entity2681 @entity1792 @entity3760 @entity7034 @entity1388 @entity291
UNASSIGNED: The aim of this study was to compare the protective effects of solutions containing stannous (Sn), @entity1388 (F) and their combination in the prevention of dentin @entity2681 . Forty @entity291 root dentin specimens (4'4'2 mm3) were prepared and randomly assigned to 4 groups (n = 10): @entity18360 (800 ppm/6.7 mM Sn), @entity7034 (250 ppm/13 mM F), @entity7034 / @entity18360 (800 ppm/6.7 mM Sn; 250 ppm/13 mM F), and deionized water (DIW) as a negative control. An acquired pellicle was formed on dentin samples by incubation in clarified, pooled, stimulated @entity1 saliva for 24 hours. The specimens were subjected to 5 daily cycles, each consisting of 5 of min @entity3760 (0.3%/15.6 mM @entity1792 , pH 2.6, 6'/day) and 60 min of re-mineralization in clarified @entity1 saliva. Thirty minutes after the 1st, 3rd and 5th @entity3760 episodes of each day, the specimens were treated with one of the test solutions for 2 min. Surface loss was measured via optical profilometry. Mixed-model ANOVA followed by Tukey's test were used for the statistical analysis. Sn, F, and their combination significantly reduced the dentin surface loss by 23%, 36%, and 60% compared with DIW, respectively. All groups were significantly different (p < 0.05). The combination of Sn and F significantly reduced the amount of dentin surface loss compared with all other groups. The F group also significantly reduced surface loss compared with Sn and DIW, followed by the Sn group, which showed significantly greater protection compared with the DIW control. The daily use of a combined @entity1388 and stannous solution is promising for preventing dentin @entity2681 .
