s-IgA response in females following a single bout of moderate intensity exercise in XXXX and thermoneutral environments.

@entity5032 @entity26636
Previous research has linked exercise under unfavourable environmental conditions to decreased concentration and/or secretion rate of secretory immunoglobulin A (s-IgA). The purpose of this study was to investigate the influence of moderate exercise in a thermoneutral (TN) and a @entity5032 ( @entity26636 ) environment on the concentration of s-IgA and the secretion rate of s-IgA in moderately active females. Sixteen females (23.4 +/- 6.8 yrs, 61.1 +/- 5.9 kg, 1.64 +/- 0.07 m) served as subjects for this study. On separate occasions, one week apart, all subjects ran or walked for 30 minutes at 71 % of individual heart rate reserve on an outdoor (1 degrees C) or an indoor track (24 degrees C). Unstimulated saliva samples were collected for 4-min immediately pre (PR), post (POST), and 30-min post (30POST) exercise. Profile of Mood State (POMS) questionnaires were completed pre and post exercise intervention and Global Mood State (GMS) was calculated. The absolute concentration of s-IgA, and total non-specific protein were measured and the secretion rate of s-IgA and s-IgA:Protein were calculated. Analysis of Variance (ANOVA) revealed that flow rate increased in @entity26636 and decreased in TN such that it was significantly lower (POST) and (30POST) in the TN environment when compared to @entity26636 . There was a significant increase in the secretion rate of s-IgA at 30POST for the @entity26636 trial and a significant decrease at 30POST for the TN trial. No significant differences were found for the concentration of s-IgA, the s-IgA:Protein:ratio, or GMS. Stepwise regression revealed that with all predictors in the model, only the concentration of s-IgA accounted for a significant proportion of the variance in @entity5032 temperature, while in the TN environment, both the concentration of s-IgA and the flow rate accounted for significant proportions of the variance. These findings suggest that moderate exercise in @entity5032 temperatures does not decrease secretion rate of s-IgA, while exercise in TN temperatures does.
