De novo XXXX on renal allografts.

@entity1 @entity8 @entity6 @entity2316 @entity1011
BACKGROUND: @entity6 ( @entity6 ) is a well-recognized clinical problem following renal transplantation. Long-term risks of @entity6 are similar to those of @entity6 in general population. The aim of our study was to identify de novo @entity2316 ( @entity2316 ) in our group of @entity1 with @entity6 . METHODS: Thirty-four @entity1 with @entity6 were reviewed retrospectively. Light microscopy, immunofluorescence, and electron microscopy techniques were performed in 10 of 21 @entity1 with graft biopsy. RESULTS: Five @entity1 (four @entity1 , one @entity1 ), aged 47.4 years (range, 29 to 58), four of whom received cadaveric grafts, were found to have de novo @entity2316 . Their serum @entity1011 was 211.4 micromol/L (range, 140 to 294). Three @entity1 were slightly proteinuric (0.3 to 0.5 g/L). @entity6 was diagnosed 2.4 months after transplantation (range, 1 to 6). Histologic diagnosis of de novo @entity2316 was made, on average, 52.6 months after transplantation (range, 8 to 115), and 50.2 months (range, 2 to 114) after @entity6 . De novo @entity2316 presented as @entity6 in four @entity1 and nodular @entity6 in one @entity1 , and combined with @entity8 in all five @entity1 . The mean graft survival time for this group of @entity1 was equivalent with a control group. Although the difference in slopes of serum @entity1011 between the studied groups was clinically relevant, it was not statistically significant. CONCLUSION: In view of our findings, when histologic de novo @entity2316 was found in 5 out of 10 @entity1 , one could conclude that de novo @entity2316 could be a frequent complication of @entity6 .
