A Multicentered Prospective Analysis of Diagnosis, Risk Factors, and Outcomes Associated With XXXX *

@entity1 @entity2489
OBJECTIVE:: To assess risk factors and outcomes associated with pediatric @entity2489 . DESIGN:: Multicentered prospective observational cohort. SETTING:: @entity1 's hospitals in the United States. @entity1 :: Mechanically ventilated @entity1 less than 18 years old. MEASUREMENTS AND MAIN RESULTS:: Prospective evaluation of the prevalence, risk factors, and outcomes of pediatric @entity2489 along with evaluation of diagnostic criterion for pediatric @entity2489 . The prevalence of pediatric @entity2489 was 5.2% (n = 2,082), for a rate of 7.1/1,000 ventilator days. @entity1 with @entity2489 had a longer unadjusted ICU length of stay (p < 0.0001) and increased length of mechanical ventilation by more than 11 days (p < 0.0001). After adjustment for @entity1 factors, ICU length of stay (p = 0.03) and mechanical ventilation days (p = 0.001) remained significant. @entity1 with @entity2489 were almost three times more likely to die (p = 0.007). Independent risk factors for @entity2489 were reintubation and part-time ventilation. CONCLUSIONS:: Pediatric @entity2489 is common in mechanically ventilated pediatric @entity1 . These @entity1 have longer length of stay, longer duration of mechanical ventilation, and increased risk for mortality.
