Advanced XXXX is associated with unsuccessful maze operation for valvular @entity955 .

@entity1 @entity82 @entity384 @entity1711 @entity1710 @entity86 @entity955
OBJECTIVE: @entity384 and @entity82 are considered to be important factors in the occurrence and maintenance of @entity955 ( @entity955 ). However, the relationship between those @entity86 after a maze operation has been rarely studied. The purpose of this study was to determine whether pathological evaluation of atrial tissues was useful for predicting an unsuccessful maze operation in @entity1 with @entity955 . METHODS: Between March 2006 and June 2007, left-atrial tissues in the posterior wall and right-atrial appendage were obtained from 47 consecutive @entity1 (24 @entity1 with chronic @entity955 , and 23 with sinus rhythm) undergoing mitral valve surgery (MVS). A concomitant maze operation was performed for all @entity1 with chronic @entity955 . Atrial cell diameters were measured using @entity1710 and @entity1711 staining, and quantitative assessment of atrial @entity82 was performed with Masson trichrome staining using an image analyzer (Image Processor for Analytical Pathology, Sumika Technoservice Co., Hyogo, Japan). RESULTS: Successful MVS was performed for all @entity1 and there were no complications associated with tissue sampling. @entity1 with chronic @entity955 had more advanced histological features in both atria as compared with those with sinus rhythm. Sixteen of 24 @entity1 , who underwent a maze operation, had successfully restored sinus rhythm (successful maze group), while that in the remaining eight was not restored (unsuccessful maze group). @entity1 in the unsuccessful maze group had a larger left-atrial dimension and cardiothoracic ratio as compared with those in the successful group, whereas the duration of @entity955 was not significantly different. @entity1 in the unsuccessful maze group also had greater hypertrophy of cardiomyocytes and more extensive intercellular @entity82 in the left atrium, while there were no differences for right-atrial pathological features between the groups. Multivariate logistic analysis confirmed that a larger amount of @entity82 (>15%) was significantly associated with an unsuccessful maze operation. CONCLUSIONS: The present results suggested that advanced @entity82 in the left atrium, but not in the right atrium, might be significantly associated with an unsuccessful maze operation in @entity1 with @entity955 .
