The effect of cold @entity63 on the patency of microvascular repair following arterial XXXX .

@entity63 @entity16 @entity95 @entity177 @entity155 @entity715 @entity2096 @entity130
@entity130 have a poor prognosis for survival in clinical replantation surgery. Arterial @entity715 is the most significant factor contributing to @entity177 , and severe @entity16 has been observed with this injury. However, patency rates of experimentally @entity155 arteries repaired immediately are much higher than in the clinical situation. This paper evaluates the effect of an added component-- @entity63 --on the patency of experimentally @entity155 arteries. All @entity155 seen clinically are subject to some degree of @entity63 prior to replantation. Ninety @entity95 had both femoral arteries @entity155 under general anesthesia. A 6.5-cm graft was harvested from the @entity2096 . In 20 @entity95 (group 1: 0 hours of @entity63 ) the graft was immediately inserted into the defect in the right femoral artery. Sixty @entity95 (20 grafts per group) had their grafts stored at 4 degrees C for either 10 hours (group 2), 18 hours (group 3), or 24 hours (group 4) and reinserted into the right femoral artery in a second operation. Patency was assessed 3 weeks after reinsertion. Groups 1 and 2 maintained high patency rates (85 percent); however, group 3 (70 percent) and group 4 (45 percent) had lower patency rates than group 1, with a significant difference between groups 1 and 4 (p < 0.01). In a fifth group (10 grafts), @entity155 24-hour @entity63 grafts were hydrodilated prior to reinsertion. The patency rate of this group increased significantly (90 percent) compared with group 4 (p < 0.005). CONCLUSION: These experiments suggest that a combination of @entity130 and @entity63 time is responsible for the poor clinical results of @entity155 replantations.
