Do the laryngopharyngeal symptoms and signs ameliorate by empiric treatment in @entity1 with suspected XXXX ?

@entity1 @entity304 @entity37462 @entity51 @entity354 @entity8823
OBJECTIVES: In clinical practice, antireflux medication is given almost always empirically without pH monitorization. We aimed to evaluate the improving effect of empiric antireflux treatment on layngopharyngeal symptoms and signs in @entity1 with @entity354 ( @entity354 ) and suspected @entity8823 ( @entity8823 ) according to @entity304 ( @entity304 ) and @entity51 ( @entity51 ). METHODS: @entity354 was determined by esophagogastroduedonoscopy and biopsy in 127 @entity1 . @entity304 and @entity51 were calculated for each @entity1 . The @entity1 with a pathology other than @entity37462 which may be responsible from laryngopharyngeal symptoms and signs were excluded from the study. Fifty @entity1 whom were thought to have @entity8823 according to @entity304 and @entity51 comprised the study group. After 12-weeks of antireflux treatment, @entity304 and @entity51 were calculated again. The statistical analyses were made according to the changes in the severity and frequency of each symptom and sign. RESULTS: There was statistically significant improvement in @entity304 and @entity51 after treatment when compared with initial scores. There was statistically significant improvement in severity of all symptoms and signs. Although there was quantitively decrease in frequency of some signs and symptoms, complete resolution of the disease was not observed generally. CONCLUSION: Empiric antireflux treatment according to @entity304 and @entity51 is an effective method. Antireflux treatment has a significant improving effect on laryngopharyngeal symptoms and signs. There may be needed longer times of treatment for complete resolution of symptoms and signs.
