XXXX caused by Apophysomyces elegans.

@entity1 @entity32 @entity2583 @entity6 @entity2379 @entity542 @entity281 @entity735 @entity158 @entity130
@entity2583 ( @entity2583 ) caused by more common zygomycetes (e.g., Mucor) is known to cause rapidly fatal @entity281 in immunocompromised @entity1 . Apophysomyces elegans is an emerging zygomycete that has been reported to cause invasive @entity281 in immunocompetent individuals. Limited data exist describing the syndrome of @entity2583 caused by A. elegans. We describe a recent case and performed a comprehensive literature review to delineate the clinical characteristics of @entity2583 caused by A. elegans. Our case is a 50-year-old @entity1 with @entity6 who presented with @entity158 and @entity735 . Endoscopic sinus sampling revealed A. elegans. He was treated with liposomal @entity2379 and multiple debridements, with no disease on 1.5-year follow-up examination. Seven cases were identified on literature review, including the present case. Most @entity1 (86%) were male, with a mean age of 40 years. Most @entity1 (71%) did not have predisposing medical conditions. Three @entity1 had predisposing @entity542 . All presented with @entity158 . All had magnetic resonance imaging or computed tomography of the head showing @entity32 . Diagnosis was confirmed by histopathology and deep tissue culture in all cases. All @entity1 required eye exenteration and extensive surgical debridement, in addition to intravenous @entity2379 . Six of the seven @entity1 (86%) recovered. @entity2583 caused by A. elegans is rarely reported in the literature. Most such @entity281 occurred in immunocompetent @entity1 , often after facial @entity130 . Survival in @entity2583 caused by A. elegans is favorable in reported cases, with prompt surgical debridement and antifungal therapy.
