Remodeling of the XXXX gingiva induced by @entity515 laser coagulation mode.

@entity1603 @entity39 @entity8650 @entity18273 @entity515 @entity35
BACKGROUND AND OBJECTIVES: This study was conducted to clarify the morphologic characteristics and subsequent repair process of coagulation @entity39 produced by pulsed @entity515 laser irradiation with relatively low fluence, and thereby to evaluate the clinical efficacy of this irradiation mode. STUDY DESIGN/MATERIALS AND METHODS: Wounding of @entity35 gingiva to produce coagulation @entity39 was done with a @entity515 laser with a fluence of 326 J/cm(2). The structural characteristics of the wound and subsequent repair process were examined by means of histology, immunohistochemistry, and electron microscopy. RESULTS: At 6 hours after irradiation, the cells in the laser wound appeared histologically intact but had lost the immunoreactivity to antibodies against Hsp47 and exhibited various ultrastructural signs of cell death. This wound area was lined by @entity18273 -positive cells. At 1-day post-irradiation, the uptake of @entity1603 rapidly increased in the adjacent epithelium and connective tissue. The re-epithelization commenced at 1 day and was completed by 7 days. The @entity39 tissue gradually became integrated within the newly formed connective tissue and the original contour of the gingiva was retained during the repair process. The repair process of the laser-induced wound progressed more rapidly than that of a scalpel-made wound. CONCLUSIONS: The present study suggests that the coagulation @entity39 produced by the low fluence pulsed @entity515 laser does not disturb the repair process but promotes its steady progress and subsequent tissue remodeling. This laser mode will pave the way for more conservative and minimally invasive surgery for treating a wide variety of @entity8650 .
