Assessment of major adverse cardiovascular events and XXXX with coronary computed tomography angiography based upon angiographic diagnosis in a high-volume single center.

@entity1 @entity583 @entity460 @entity453 @entity385
BACKGROUND: @entity1 prognosis has been shown to directly correlate with the severity of @entity453 diagnosed by coronary computed tomography angiography (CCTA). Although the presence of coronary artery @entity460 has been associated with increased incidence of @entity385 , there are no data on the incidence of @entity385 based upon the severity of @entity453 by CCTA. Therefore, we sought to investigate the rate of major adverse cardiovascular events, including @entity385 , based upon the severity of @entity453 by CCTA over a 6-year period in a high-volume single military center. METHODS: We performed a retrospective chart review of all CCTA studies to evaluate the incidence of all-cause mortality, non-fatal @entity583 , @entity385 , and late revascularization (>90 days following CCTA) from January 2005 until July 2012. We reviewed 1518 CCTA reports, dividing @entity1 into groups with obstructive (>= 50% stenosis), non-obstructive (<50% stenosis), and no @entity453 (no angiographic disease). Subsequent major adverse cardiovascular events data (incidence of all-cause mortality, @entity385 , non-fatal @entity583 , and late revascularization) were obtained. RESULTS: Over a review period of 6 years with a resultant median follow-up period of 22 months (interquartile range = 13-34 months), the major adverse cardiovascular events rate was significantly higher with obstructive @entity453 compared to both @entity453 and no @entity453 (8.9% vs 0.7%, p < 0.001; 8.9% vs 1.6%, p < 0.001). The incidence of @entity385 alone was also significantly higher in those with obstructive @entity453 compared to those with no @entity453 (3.8% vs 0.4%, p < 0.001). CONCLUSION: Being free of disease on CCTA was associated with excellent cardiovascular prognosis. Obstructive @entity453 was associated with a significantly increased incidence of @entity385 . There was also a direct correlation between the severity of @entity453 on CCTA and cardiovascular prognosis over the follow-up period of 24 months.
