Prevention of XXXX in bobwhites by medication.

@entity31295 @entity6193 @entity308 @entity7843 @entity7844 @entity1017
The efficacy of @entity31295 , @entity6193 , and @entity7844 in preventing @entity7843 in bobwhite quail was studied using a mixed inoculum of equal numbers of Eimeria dispersa and E. lettyae. A total dosage per quail of 10(6) sporulated oocysts was chosen because this dosage gave a good (77%) @entity308 of @entity1017 from Day 18 to Day 24. Levels of .008% @entity6193 or .0055% @entity7844 were the most effective for prevention of @entity7843 as evaluated by body weight gains. These levels significantly reduced parasite numbers in the duodenum with @entity6193 administration and in both the duodenum and ileum with @entity7844 administration. @entity6193 reduced parasite numbers in the illeum significantly in one experiment and in a second. Amprolium was ineffective for prevention of @entity7843 , as evaluated by body weight gains. Amprolium was also ineffective in consistently reducing parasite numbers in the duodenum and ileum. Both @entity6193 and @entity7844 had a reasonable safety margin in quail. Levels of @entity6193 of .016%, twice the proposed level, significantly reduced body weight at 14 days of age compared with unmedicated controls or quail given .008% @entity6193 . By 28 days, however, this effect was no longer significant. Levels of @entity7844 at the proposed level of .0055% significantly reduced body weight at 14 days of age compared with unmedicated controls. By 28 days, however, this effect was no longer significant in quail given .0055% or .00825% @entity7844 , although in quail fed .011% @entity7844 body weights remained significantly lower (16.5%) at that date. There were no detectable @entity6193 residues in the liver of quail fed a ration containing .008% @entity6193 for 8 wk.(ABSTRACT TRUNCATED AT 250 WORDS)
