Willingness-to-pay stated preferences for 8 health-related quality-of-life domains in XXXX : a pilot study.

@entity1 @entity1569 @entity625 @entity5144
OBJECTIVES: @entity5144 ( @entity5144 ) is a seronegative @entity625 found in up to 5 to 42% of @entity1 with @entity1569 . As current instruments do not fully capture health-related quality of life (HR-QOL) in @entity5144 from the @entity1 's perspective, we piloted a novel application of "willingness-to-pay" (WTP) as a @entity1 Reported Outcome to measure the relative impact of @entity5144 in 8 domains of HR-QOL. METHODS: Fifty-nine @entity5144 @entity1 were interviewed on 8 WTP HR-QOL domains (physical, emotional, sleep, work, social, self-care, intimacy, and concentration). @entity1 were asked to rank the 8 domains of health in order of HR-QOL impact. In each domain, @entity1 were asked whether @entity5144 affected that domain, whether they were willing to pay for a cure in that domain, and the amount they were willing to pay. Median WTP amounts were compared with the proportion of @entity1 affected by and willing to pay in each domain. Responses in US dollars were interpreted as strength of preference rather than absolute monetary values. RESULTS: The majority of @entity1 were white (98%), > or =45 years of age (70%), insured (98%), and earned > 65,000/yr (66%). The physical domain was most affected by @entity5144 ; intimacy and concentration were ranked lowest. @entity1 reported a wide range of WTP amounts ( 0 to  1,000,000), and median WTP amounts were highest in the physical, work, sleep, and self-care domains. Related domains elicited median WTP amounts that were highly correlated. No significant differences in median WTP amounts were found across ages, genders, and income levels for the different domains. CONCLUSIONS: WTP is a novel quantitative @entity1 -perspective measure that is comprehensible and feasible to administer in @entity5144 @entity1 . It represents a unique tool for capturing the complex manifestations of @entity5144 and its impact on the individual, allowing the quantification of specific HR-QOL parameters and providing the potential for comparison across various disease processes in a given individual.
