The hemodynamic and humoral responses to tilting in @entity6 XXXX on chronic hemodialysis treatment.

@entity1 @entity64 @entity6 @entity1425 @entity916 @entity3918 @entity1063
Hemodynamic and humoral responses to tilting were examined in order to elucidate the autonomic nervous function in @entity6 @entity1 . Eleven @entity6 ( @entity3918 ) and eleven non- @entity6 (non- @entity3918 ) @entity1 on maintenance hemodialysis treatment were involved in the experimentation, matching the age and the duration of hemodialysis. Cardiac output, blood pressure, plasma @entity916 activity (PRA), @entity1063 (NE) and @entity1425 (EP) were measured before and 5 minutes after the 45 degree tilting. By the tilting the blood pressure significantly fell in @entity3918 , whereas it rose slightly but significantly in non- @entity3918 . In both groups, however, the heart rate remained unchanged, and either cardiac index or @entity64 volume index decreased equally. The percentile increase in total peripheral resistance index (TPRI) was significantly smaller in @entity3918 (14.6%) than in non- @entity3918 (27.9%). There was a significant correlation between the changes in TPRI and diastolic blood pressure (r = 0.730, p less than 0.01). NE and EP increased significantly in non- @entity3918 but not in @entity3918 . Blood pressure reduced by the tilting in @entity3918 was associated with a small or equivocal response in either TPRI or plasma NE. The heart rate did not respond to the tilting in both groups. These results indicate that both sympathetic and parasympathetic nervous systems are deranged in @entity6 @entity1 but parasympathetic dysfunction is evident even in non- @entity6 @entity1 .
