First evidence of XXXX to argan powder in a cosmetic factory.

@entity1 @entity566 @entity2490 @entity7446 @entity2710
BACKGROUND: Argan is used worldwide in numerous cosmetic products, as this fruit is supposed to have many beneficial properties on health. New cases of @entity566 can be expected with the growing use of argan. We investigated all workers (9) employed by a cosmetic factory and exposed to argan powder to identify possible @entity566 related to exposure to argan powder. METHODS: @entity1 were investigated in the occupational disease department and, according to their symptoms, underwent pulmonary function testing, @entity2710 challenge, specific inhalation challenge to argan powder, skin prick tests and immunoblotting analysis. RESULTS: We report three cases of @entity7446 to argan powder and a probable case of @entity2490 . Fifteen argan proteins were recognized by the @entity1 ' IgE. Identification of proteins, cross-reactions to nuts and ELISA inhibition tests suggested that some argan allergens can cross-react in vitro with hazelnut allergens, including 11S globulin and vicilin. CONCLUSION: High-level exposure to argan powder should be considered to be a potential cause of IgE-mediated @entity566 and workers handling argan powder should be carefully investigated. This article is protected by copyright. All rights reserved.
