Effects of percutaneous transluminal angioplasty on skin microcirculation in @entity1 with disabling peripheral XXXX .

@entity1 @entity26 @entity887 @entity865 @entity432 @entity731 @entity130
Percutaneous transluminal angioplasty ( @entity865 ) provokes a huge @entity130 to the arterial wall and potentially liberates fragments of @entity731 material that may impair the microcirculation downstream. Incidence and clinical relevance of such @entity887 are not known. This study was aimed at investigating the changes of the skin microcirculation in @entity1 with peripheral @entity432 undergoing @entity865 of the lower limbs. Pedal transcutaneous @entity26 tension (tcpO2) and nailfold skin microcirculation were measured in 21 @entity1 with disabling peripheral @entity432 before and after @entity865 . Sixteen matched @entity1 undergoing arteriography alone were used as controls. The skin microcirculation was investigated at the nailfold of the great toe by the combination of laser Doppler fluxmetry and dynamic capillaroscopy. @entity865 was successful in all @entity1 . The tcpO2 decreased immediately after @entity865 (delta tcpO2 = -5 mm Hg; p < 0.004), whereas it tended to increase (delta tcpO2 = 1 mm Hg; NS) following arteriography as compared with baseline values. By contrast, blood flow increased in both groups, predominantly for the total circulation in the @entity865 group and for nutritional circulation (p < 0.0017) in the arteriography group, respectively. Consequently, the 'nutritional index', i.e., the index of nutritional versus total microcirculation, was decreased following @entity865 , particularly following mechanical recanalization (p < 0.02), but did not change in the controls. The changes of this 'nutritional index' and those of the tcpO2 were positively correlated (r = 0.4, p = 0.023).(ABSTRACT TRUNCATED AT 250 WORDS)
