Metastatic XXXX in a @entity1 with massive @entity1151 .

@entity1 @entity129 @entity932 @entity146 @entity5 @entity2 @entity3977 @entity2879 @entity1151 @entity519 @entity1188 @entity3580 @entity1282 @entity1260 @entity3
A 27-month-old @entity1 of Hispanic background developed @entity129 , @entity1282 , bloody nasal discharge, and @entity146 . Radiographic evaluations showed extensive destruction of the clivus by a large @entity5 that invaded the sphenoid bone, left cavernous sinus, ethmoid sinus, nasal cavity, and left orbit. @entity3977 were also noted. The bone marrow and spinal fluid showed no evident @entity5 cells. Transnasal biopsy revealed a @entity3580 . Treatment was initiated with a combination of @entity1260 , mesna, and @entity2879 along with radiation therapy to the @entity5 . Shifting pulmonary densities were noted on serial films. Despite some clinical improvement, the @entity1 developed rapidly progressive @entity519 3 weeks after admission and died. Autopsy showed persistent viable @entity5 in the primary site and massive @entity2 emboli, @entity1188 , and widespread lung parenchymal @entity3 . No other sites of @entity5 involvement were discovered. This is the second @entity1 reported with @entity932 , pulmonary @entity3 at diagnosis, and early death attributed to @entity1151 .
