Gender-specific association between urinary XXXX excretion and body composition: Analysis of the 2008-2010 Korean National Health and Nutrition Examination Surveys.

@entity1 @entity28 @entity1372 @entity9037 @entity6288
OBJECTIVE: Few studies have reported the relationship between @entity6288 and the estimated amount of @entity1372 excreted in 24 h, as measured by the spot urine test (E24UNA), in a community-dwelling cohort. We investigated the gender specific association between E24UNA values and body composition indices. MATERIALS AND METHODS: Data from a total of 7162 @entity1 (3545 @entity1 and 3617 postmenopausal @entity1 ) aged 45 years or older were obtained from multiple Korea National Health and Nutrition Examination Surveys (2008-2010) and analyzed. The total amount of @entity1372 excreted in the urine in a 24-h period was estimated with spot urine specimens. @entity6288 was defined as an appendicular skeletal muscle mass divided by body weight ( @entity9037 /Wt) that was less than 1 standard deviation below the sex-specific mean for young adults. RESULTS: E24UNA values were positively correlated with body mass index, waist circumference, total fat mass, and blood pressure; in contrast, E24UNA values were negatively correlated with @entity9037 /Wt in both sexes. Compared with those in the lowest E24UNA tertile, @entity1 in the highest E24UNA tertile were at higher risk for @entity6288 ( @entity1 : odds ratio (OR)=1.3 [95% confidence interval (CI)=1.07-1.59]; @entity1 : OR=1.41 [95% CI=1.16-1.73]). Further classification of subjects with @entity6288 into @entity28 and sarcopenic nonobese groups revealed that the highest E24UNA values were found in the @entity28 group; this difference was statistically significant. The next highest levels were found in the sarcopenic nonobese group, followed by the nonsarcopenic group. This trend was observed in both sexes. CONCLUSION: High E24UNA values were independently associated with both @entity6288 and @entity28 in Korean individuals older than 45 years. These results suggest that high salt intake may have a deleterious effect on body composition.
