Temporal profile of hilar basal dendrite formation on dentate granule cells after XXXX .

@entity410 @entity2134 @entity1315 @entity5702 @entity1251 @entity35 @entity159
Granule cells with @entity5702 ( @entity5702 ) are found after @entity159 ( @entity159 ) in three @entity35 models of @entity1315 . These granule cells are commonly located at the hilar border and could be newly born granule cells based on their location. The aim of this study was to determine how long it takes for @entity5702 to form on granule cells after @entity159 . @entity2134 was injected to induce @entity159 and @entity35 were killed at different times: 3 days, 1, 2, and 3 weeks after @entity159 . Biocytin was injected into @entity1251 stratum lucidum of hippocampal slices to label granule cells with @entity5702 . The number, morphology, and length of @entity5702 were analyzed at the different time points. Basal processes of granule cells from @entity35 killed 3 days after @entity2134 injection were judged not to be @entity5702 because they were short in length and did not ramify in the hilus. "True" @entity5702 were detected as early as 7 and 8 days after @entity2134 -induced @entity159 . Similar frequencies of granule cells with @entity5702 were observed at the later time points. This study shows that @entity5702 can form on granule cells as early as 1 week following @entity159 . These results are consistent with the hypothesis that @entity5702 on granule cells may be generated from @entity410 -induced, de novo granule cells, however, alternative explanations that some or all @entity5702 arise from pre- @entity159 generated granule cells cannot be ruled out at this time and will require further examination.
