Gender differences in sensitivity of @entity934 and XXXX to @entity3361 provocation test.

@entity1 @entity662 @entity3361 @entity2473 @entity3451 @entity3693 @entity934
UNASSIGNED: We examined the sex difference concerning the coronary artery response between @entity3451 and ER in this study. We already reported the difference of coronary response between @entity934 ( @entity3451 ) and @entity3693 (ER). We performed both @entity3451 and ER tests of 461 @entity1 (male 294 @entity1 , female 167 @entity1 , mean age 64.4      11.3  years) during 23  years. Positive @entity3361 was defined as >99  % transient luminal narrowing with usual @entity662 and/or ischemic ECG changes. Firstly, @entity3451 was administered in incremental doses of 20/50/(80)   g into the RCA and 20/50/100/(200)   g into the LCA over 20  s. Secondly, ER was administered in a total dose of 40   g into the RCA and of 64   g into the LCA over 2-4  min. Intracoronary injection of @entity3451 and ER provoked @entity2473 in 221 @entity1 consisting of 160 male @entity1 and 61 female @entity1 . In female @entity1 , the @entity2473 provoked by @entity3451 was almost perfect except in two @entity1 (59 @entity1 , 96.7  %), while ER provoked @entity2473 in only 20 @entity1 (32.8  %). In male @entity1 , provoked @entity2473 by @entity3451 (129 @entity1 , 80.6  %) was significantly higher than ER (97 @entity1 , 60.6  %). As a @entity2473 provocation test, @entity3451 is more sensitive than ER in both sexes and especially in females. We may select two pharmacological agents by sex differences to provoke @entity3361 in the cardiac catheterization laboratory in the future.
