Carotid XXXX : natural history.

@entity1 @entity64 @entity101 @entity6 @entity63 @entity117 @entity432 @entity204
During a 5-year period, 212 @entity1 (170 @entity1 and 42 @entity1 , median age 65 and 64 years, respectively) were diagnosed as having internal carotid @entity432 . Mean follow-up was 24.9 months. Five-year cumulative survival and @entity64 -free rates by life-table analysis were 62% and 75%, respectively. @entity204 were due to @entity64 in 7 of 40 @entity1 (17%) and were of cardiac origin in 22 of 40 @entity1 (55%). The @entity64 were ipsilateral in 20 of 31 @entity1 (65%). No statistically significant difference between the sexes could be demonstrated for either @entity204 or @entity64 , nor was age correlated with @entity64 during follow-up. @entity6 and @entity101 increased the risk of @entity64 , whereas gender and @entity117 consumption had no discernible effect. Endarterectomy of the opposite carotid artery did not significantly affect the natural history but did reduce the @entity64 rate in the territory of the operated artery. Presenting symptoms were useful for estimating prognosis. Twenty-two of 111 @entity1 referred for @entity64 (20%) suffered a further @entity64 and 21 of 111 @entity1 (19%) died (three were @entity64 -related), whereas of those @entity1 referred for @entity63 ( @entity63 ), only 2 of 42 @entity1 (5%) suffered a @entity64 and none died. TIAs occurred in 23 @entity1 (11%) during follow-up, and these were premonitory for @entity64 in three cases (13%). The limited value of @entity63 in predicting @entity64 and the high mortality rate unrelated to @entity64 in this group are important considerations when therapy is considered for these @entity1 .
