Neuronal responsiveness to gonadotropin-releasing hormone and its correlation with sexual receptivity in the XXXX .

@entity172 @entity1420 @entity134 @entity1515 @entity1176 @entity35
In the present study, an attempt was made to correlate the neuronal responsiveness of individual preoptic-septal (POA/S) units to iontophoretically applied @entity1176 with the onset of sexual receptivity. In both behavioral and electrophysiological studies, ovariectomized, @entity172 -primed @entity35 were used. In behaviorally tested @entity35 , @entity1515 quotients (LQ) were determined at varying times following @entity1420 (P) injection. For electrophysiological studies, P was given 1 hr after the start of recording. @entity1176 was iontophoretically applied for 30 sec at 16 nA on spontaneously discharging cells. A unit was deemed excited or inhibited if a repeatable 30% change in discharge rate was observed. From 2-10 hours as the LQ increased from 17 to 90 the total number of @entity1176 sensitive cells did also. The majority of responsive cells were excited by the peptide. As receptivity displayed a sharp increase from 2 to 6 hours the mean responsiveness of cells excited by @entity1176 was significantly elevated over inhibitory responses. These findings confirm the E/P biasing effect on POA/S unit responses to @entity1176 . Moreover, they suggest that a dynamic relationship exists between @entity1176 responses at the cellular level and sexual behavior throughout the course of @entity134 -induced receptivity.
