@entity5 -associated hypercalcaemia in XXXX : a survival and prognostic factor analysis.

@entity1 @entity957 @entity5 @entity3
The aim of this study is to analyse survival and prognostic factors in @entity1 diagnosed with @entity957 ( @entity957 ) presenting a first episode of @entity5 ( @entity5 ). Retrospectively, the authors reviewed data from 220 @entity1 with biopsy proven @entity957 who presented a first episode of @entity5 . They were treated in a single centre between 1995 and 2007. The survival analyses were done using the Kaplan-Meier method and Cox analysis. The primary endpoint was the overall survival from the date of hypercalcaemia episode. Median age was 55 years. Median survival was 64 days (1-197). Three independent prognostic factors were identified: brain @entity3 (hazard ratio (HR)=2.58 CI (1.03-6.45)), corrected calcaemia>3 mmol/l (HR=1.45 CI (1.05-2.01)) and hypoalbuminaemia (HR=1.48 CI (1.07-2.04)). Using these factors, the authors performed a bedside prognostic score. In conclusion, median survival in @entity1 diagnosed with @entity957 and @entity5 is extremely poor. The bedside prognostic score that the authors developed can help to anticipate @entity1 ' prognosis and adapt the treatment. This score needs to be validated on an independent cohort.
