Association of XXXX with @entity75 : the Ohasama study.

@entity64 @entity66 @entity75 @entity73 @entity1188 @entity432 @entity62 @entity385
BACKGROUND: Arterial stiffness is a risk factor for symptomatic @entity64 , and is associated with symptomatic @entity385 and @entity73 . Hence, we hypothesized that @entity432 would be a significant determinant of @entity75 . METHODS: The subjects were 363 individuals without symptomatic @entity75 who had their @entity432 assessed by brachial-ankle pulse wave velocity (baPWV) measurement. The subjects were classified into two groups by the presence or absence of @entity1188 , as well as into three groups by grade of @entity62 ( @entity62 ). baPWV was compared among these groups. RESULTS: Eighty-six subjects had @entity1188 . Of 138 subjects with WMHs, 102 were classified as having grade 1 and 36 as having grade 2 or 3 WMHs. baPWV was significantly higher in subjects with @entity1188 than in those without (17.3    0.3 vs. 16.4    0.2 m/s). baPWV tended to increase with higher @entity62 grade (16.2    0.2, 16.9    0.3, and 17.8    0.5 m/s in grade 0, 1, and 2 or 3, respectively) after adjustments for confounding factors. The adjusted odds ratio (OR) for @entity1188 in subjects with middle-tertile baPWV was significantly higher (OR, 2.37; 95% confidence interval, CI, 1.10-5.11) and the OR in subjects with the highest-tertile baPWV tended to be higher (OR 2.26; 95% CI 0.99-5.45) compared with the lowest-tertile baPWV. The adjusted OR for @entity62 tended to increase with increased baPWV. CONCLUSIONS: Arterial stiffness appeared to be associated with the presence of a @entity1188 and @entity62 , independently of the risks for other @entity66 .
