XXXX : long-term outcomes after resection.

@entity1 @entity66 @entity146 @entity5 @entity2
BACKGROUND: @entity5 are considered as a relatively uncommon and less malignant group of @entity2 . However, @entity1 with histologically @entity66 are known to have a worse prognosis. The present study aims to evaluate the long-term outcomes after resection of @entity5 according to the new @entity5 ( @entity5 ) staging system. METHODS: @entity1 with histologically proven @entity5 who underwent surgery in our thoracic unit over the last 25 years were identified from a prospectively collected database. RESULTS: One hundred and eighty-six @entity1 were identified from our electronic database. Of these, 164 were known to have @entity66 , while 22 had @entity66 . Median overall survival was 20.0 years. The mean follow-up was 8.0 years (median 7.0 years). Univariate analysis found age over 60, @entity66 , @entity5 staging, N status, and M status to have a statistically significant influence on overall survival. Multivariate analysis found age over 60 and atypical histopathology to have a detrimental impact on overall survival. @entity1 in the atypical subgroup were found to be significantly older, and presented with higher stage disease. CONCLUSIONS: It is clear from the current study and previous reports that @entity1 with atypical histopathology have different baseline characteristics, @entity146 , and prognosis compared with @entity1 with @entity66 . The proposed @entity5 staging system appears to be applicable to @entity1 in our surgical experience, and may offer more accurate prognostic information and assist in the management plans for individuals.
