New Prophylactic and Therapeutic Strategies for XXXX .

@entity308 @entity28 @entity6 @entity16 @entity170 @entity191 @entity2493 @entity30674 @entity2252 @entity164 @entity195 @entity1566 @entity528 @entity65 @entity130 @entity385
@entity2493 production by the pineal gland in the vertebrate brain has attracted much scientific attention. Pineal @entity2493 is regulated by photoperiodicity, whereas circadian secretion of @entity2493 produced in the gastrointestinal tract is regulated by food intake. Thus, the circadian rhythm of pineal @entity2493 depends upon whether a species is diurnal or nocturnal. @entity1566 ( @entity1566 ) involves damage to the spinal cord caused by @entity130 or disease that results in compromise or loss of body function. @entity2493 is the most efficient and commonly used pharmacological antioxidant treatment for @entity1566 . @entity2493 is an @entity30674 secreted by the pineal gland during the dark phase of the circadian cycle. Neurorehabilitation is a complex medical process that focuses on improving function and repairing damaged connections in the brain and nervous system following injury. Physical activity associated with an active lifestyle reduces the risk of @entity28 , @entity65 , @entity164 2 @entity6 , @entity170 , and @entity308 and protects against @entity16 , including @entity191 , @entity195 , and @entity385 . Physical activity has been shown to increase the gene expression of several brain neurotrophins ( @entity2252 [ @entity2252 ], nerve growth factor, and galanin) and the production of mitochondrial uncoupling protein 2, which promotes neuronal survival, differentiation, and growth. In summary, @entity2493 is a neural protectant, and when combined with therapeutic exercise, the hormone prevents the progression of secondary @entity528 in @entity1566 . The present review briefly describes the pathophysiological mechanisms underlying @entity1566 , focusing on therapeutic targets and combined @entity2493 and exercise therapy, which can attenuate secondary injury mechanisms with minimal side effects.
