Combination chemotherapy with XXXX , @entity632 , cis-platinum and @entity2663 in advanced transitional cell @entity3484 .

@entity1 @entity3484 @entity632 @entity137 @entity2663 @entity150 @entity902 @entity1487
From October 1981 to October 1984, 42 consecutive @entity1 with locally advanced unresectable or metastatic transitional cell @entity3484 were treated with cis- @entity902 50 mg/m2 i.v. and @entity632 50 mg/m2 i.v. day 1, and @entity1487 500 mg/m2 i.v. and @entity2663 100 mg/m2 days 1 and 8, every 3 weeks. In the 36 evaluable @entity1 , 4 complete remissions and 15 partial remissions were noted (52.7% response rate). Of the 12 @entity1 with previously untreated, locally advanced @entity150 , 8 responded, with 3 pathologically confirmed complete remissions. @entity137 was moderate. Median survival was 44 weeks. This 4-drug combination had significant palliative activity in our @entity1 population. Its role in the preoperative setting deserves further evaluation.
