@entity731 among XXXX adults.

@entity1 @entity8 @entity455 @entity101 @entity66 @entity2791 @entity177 @entity1011 @entity731 @entity850
PURPOSE: This report describes the change in @entity731 ( @entity731 ) among @entity101 adults referred for @entity8 ( @entity8 ) scan. METHODS: From Oct 1993 through July 2008, 20,994 @entity1 had @entity8 at our center. A total of 434 @entity101 @entity1 with two or more @entity8 exams without intervention comprised the study cohort. @entity1 demographics (blood pressures, medications, serum @entity1011 levels, and data from @entity8 ) were collected. Analyses of longitudinal changes in Doppler scan parameters, blood pressures, and renal function were performed by fitting linear growth-curve models. After confirming the linearity of change in Doppler scan parameters among @entity1 with variable number of studies, estimates of mean slopes were calculated using maximum likelihood techniques. For changes in renal function, quadratic growth curves were required to describe longitudinal change. RESULTS: A total of 434 subjects (212 @entity1 [49%] and 222 @entity1 [51%]; mean age, 64.6 +/- 12.2 years) provided 1351 studies (mean, 3.2 +/- 2.4; range, 2 to 18) for 863 kidneys over a mean follow-up of 34.4 +/- 25.1 months. At baseline, 20.6% of kidneys demonstrated hemodynamically significant @entity850 . On follow-up, 72 kidneys (9.1%) demonstrated anatomic progression of disease. A total of 54 kidneys (6.9%) progressed to significant @entity850 and 18 (2.3%) progressed to occlusion. Controlling for progression of @entity8 status demonstrated a strong association with baseline kidney length (P = .0006). Significant annualized change in @entity8 was observed (cm change/year +/- standard error of the mean [SEM]: 0.042 +/- 0.011; P = .0002) among both kidneys with and without critical disease at baseline, however, decline in length was significantly greater among kidneys exhibiting progression of @entity455 (-0.152 +/- 0.028 cm/year; comparison of slopes between groups P = .0005). In the absence of progression, the presence or absence of critical @entity2791 at baseline did not affect the rate of decline in @entity8 . Fitted models for the natural log transform of serum @entity1011 demonstrated a significant increase during follow-up (P < .0001). No association was observed between change in serum @entity1011 and baseline @entity455 status, or its progression. CONCLUSION: A total of 32% of @entity101 adults referred for @entity8 demonstrated hemodynamically significant @entity2791 . Regardless of the presence or @entity66 , a small percentage of @entity1 demonstrated anatomic progression of @entity731 . A total of 9.1% demonstrated anatomic progression and 2.3% progressed to occlusion. Although anatomic progression of @entity731 was associated with an increased rate of decline in @entity8 , progression did not predict a @entity177 . Intervention for @entity731 should be selective and reserved for strict indications.
