Changes in the Pattern of XXXX in Czech Republic.

@entity1 @entity459 @entity8 @entity10189 @entity101 @entity6 @entity788 @entity1295 @entity425 @entity2963 @entity460 @entity652 @entity2742 @entity4903 @entity1374
UNASSIGNED: @entity459 ( @entity459 ) is currently the most common @entity4903 in Czech Republic after @entity6 and @entity1374 particularly in postmenopausal @entity1 . Over the past 40 years @entity459 has changed from a rare severe @entity8 with @entity101 , @entity10189 , @entity788 , easy @entity1295 and proximal @entity425 . During 43 years we have examined one of the greatest groups of @entity1 with @entity459 . In the early 1970 the estimated incidence of @entity459 in former Czechoslovakia was approximately 8 cases per 100 000 @entity1 per year. Our data showed that the incidence of @entity459 increased sharply to 24 cases per 100 000 @entity1 per year in same community with the introduction of automated serum @entity460 and iPTH measurement. The disease is four times more frequent in @entity1 as in @entity1 . The ratio @entity1 to @entity1 did not changed since 1981. However the incidence of @entity459 changed in Czech Republic from previous years, it develops around the fifth decade of life and is increasingly discovered with advancing age. The incidence of @entity101 , @entity6 , @entity2963 , @entity788 and @entity10189 among @entity1 with @entity459 is higher as compared with the incidence of these diseases in the general population. However there are still @entity1 suffering from bone and renal complication of @entity459 . Removing the @entity652 by an experienced surgeon is the first choice of treatment of @entity1 with @entity459 . The study offers valuable data on the actual state of @entity2742 @entity1 in the Czech Republic.
