Morphologic classification of microvessels in XXXX is associated with the prognosis after resection.

@entity1 @entity5 @entity2279 @entity2280 @entity157 @entity1349
BACKGROUND AND AIM: The relationship between @entity157 ( @entity157 ) and the prognosis of @entity1 still remains controversial. The aim of the present study was to investigate the prognostic significance of morphologic features of the microvessels in @entity1 with @entity157 after resection. METHODS: The paraffin-embedding specimens of 98 consecutive @entity157 @entity1 , who received primary resection between 2000 and 2002, were collected from our prospective established @entity5 bank. The intratumoral microvessels were evaluated by immunohistochemical staining for @entity2279 and @entity2280 . The disease-free survival (DFS) and @entity1349 ( @entity1349 ) of @entity1 were analyzed by Kaplan-Meier analysis and Cox proportional hazards regression model. RESULTS: There are two distinct microvessel types: capillary-like and sinusoid-like were identified in @entity5 tissues. The @entity1 could be divided into two groups according to their microvessel types. Both DFS and @entity1349 of capillary group @entity1 (n = 65) were better than those of sinusoid group @entity1 (n = 33). Multivariate analyses showed that the microvessel type was an independent risk factor for DFS (P = 0.016) and @entity1349 (P = 0.004) of this cohort. Capillary-like microvessels were more common in small @entity157 , and were significantly associated with higher microvessel density, while sinusoid-like microvessels were significantly correlated with lower microvessel density. CONCLUSIONS: The results of our study suggested that the microvessel type is an effective predictor of survival in @entity1 with @entity157 after resection, which might serve as potential novel therapeutic targets for prevention of the recurrence of @entity157 after resection.
