Prognostic value of @entity296 recognized by low-dose XXXX echocardiography in chronic @entity1002 .

@entity1 @entity296 @entity452 @entity583 @entity453 @entity204 @entity1002
This study assesses the prognostic value of @entity296 recognized as a contractile response to inotropic stimulation in @entity1 with @entity1002 in a large-scale prospective, multicenter, observational study. Four hundred twenty-five @entity1 (mean age 61 +/- 10 years) with angiographically proven @entity453 , previous (>3 months) @entity583 , and severe @entity1002 (ejection fraction <35%; mean 28 +/- 6%) were enrolled in the study. Each @entity1 underwent low-dose @entity452 echocardiography (up to 10 microg/kg/min). Myocardial viability was identified as a rest-stress variation (Delta) in the wall motion score index (WMSI), in which each segment was scored from 1 = normal to 4 = dyskinetic in a 16-segment model of the left ventricle. Myocardial viability was identified as an improvement of >/=0.40 in WMSI. All @entity1 were followed for a median of 3.1 years. One hundred eighty-eight were revascularized either by coronary artery bypass grafting (n = 118) or coronary angioplasty (n = 70). The only end point analyzed was @entity204 . In the revascularized group, @entity204 occurred in 4 of the 52 @entity1 with and in 37 of the 136 @entity1 without @entity296 (7.7% vs 27.2%, p <0.003). Kaplan-Meier survival estimates showed a better outcome for those @entity1 with compared to @entity1 without @entity296 who underwent coronary revascularization (90.1% vs 62%, p <0.0078). Thus, in severe @entity1002 , @entity296 by low-dose @entity452 echocardiography is associated with improved survival in revascularized @entity1 .
