Remembering or knowing: electrophysiological evidence for an episodic @entity2414 in XXXX .

@entity1 @entity73 @entity2414 @entity161
BACKGROUND: In @entity161 , impaired conscious retrieval of past events and facts may represent a selective cognitive @entity2414 against a background of a generalized @entity73 . We aimed to disentangle the neural subprocesses leading to this deficit applying the 'Remember/Know procedure'. METHOD: Event-related potentials (ERPs) were recorded as 14 @entity161 @entity1 and 14 controls recognized an equal mixture of previously presented old and new words. For recognized old words, @entity1 were required to judge whether recognition was associated with recollection ('Remember') or familiarity ('Know'), either reflecting episodic or semantic memory. RESULTS: @entity1 showed a lack of 'Remember responses', which led to more opportunities to make 'Know responses'. ERPs for 'Remember' compared to 'New responses' differed consistently in controls over left temporo-parietal and right frontal electrode sites. Although @entity161 @entity1 showed the same topography for this Remember old/new effect, it was apparent over temporoparietal sites for only 800 ms and over right frontal sites for 1100 ms post-stimulus. For controls, the Know old/new effect was elicited over temporo-parietal sites between 500 and 800 ms. For @entity1 , it showed a widespread maximum over frontal sites between 500 and 1100 ms. CONCLUSIONS: The shorter time course of the left temporo-parietal Remember old/new effect suggests that the @entity1 ' episodic @entity2414 was possibly mediated by a dysfunction of the mediotemporal regions. The more widespread frontal Know old/new effect in the @entity1 suggests that the prefrontly mediated processes associated with retrieval of semantic memory may be enhanced compensatorily.
