Sentinel node navigation surgery for lower XXXX .

@entity1 @entity5 @entity530 @entity3 @entity34
BACKGROUND: Lateral pelvic lymph node @entity3 is generally present in 17% of @entity1 with T3 lower @entity5 . However, such lymph node metastases cannot be accurately detected before surgery. Since 2001, we have performed sentinel node navigation surgery for @entity1 with T3 lower @entity5 considering the lymph nodes located between the @entity530 as the lateral sentinel lymph node (LSN). @entity1 AND METHODS: Between 2001 and 2010, 101 @entity1 with T3 lower @entity5 without distant @entity3 or peritoneal dissemination were prospectively enrolled in the study. @entity1 with negative lymph nodes in the mesorectum underwent only LSN dissection in the lateral pelvic space. @entity1 with metastatic lymph nodes detected in the mesorectum underwent lateral pelvic lymph node dissection (LPLD). RESULTS: Fifty-three out of the 101 @entity1 with pathologically-negative lymph nodes in the mesorectum and a negative LSN were clinically judged as having @entity34 because no recurrence was detected in the lateral pelvic space during the three years following surgery. The other 48 @entity1 underwent LPLD because of a positive lymph node in the mesorectum, and were further divided into two sub-groups, 40 with a negative and 8 with a positive LSN. Only the eight @entity1 with a positive LSN also had positive lymph nodes in the lateral pelvic space. CONCLUSION: @entity1 with T3 lower @entity5 in stage III may not require LPLD. LSN may be very useful to determine @entity34 during surgery.
