XXXX in @entity785 ( @entity2631 ).

@entity1 @entity17351 @entity82 @entity8721 @entity1223 @entity1353 @entity2407 @entity4067 @entity2631 @entity730 @entity358 @entity4423 @entity7087 @entity785
One hundred sixty-five nonsmoking @entity785 @entity1 were evaluated by pulmonary function testing. @entity358 and an isolated reduction of the diffusing capacity of @entity1223 were the most frequent abnormalities. @entity1 with the @entity4067 ( @entity730 , @entity2407 , @entity4423 , @entity17351 , and @entity8721 ) had a similar frequency and severity of @entity358 compared with the @entity1 who had @entity7087 . @entity4067 @entity1 with @entity358 rarely had the anticentromere antibody and had more skin and joint involvement of their hands, compared with other @entity4067 @entity1 . @entity1353 and rales were most commonly found in @entity1 with @entity358 . @entity82 , shown on chest radiograph, and @entity358 correlated poorly with each other. @entity1353 was associated with restrictive disease, and rales were more commonly found in @entity1 with @entity82 . @entity1 with a restrictive abnormality had the worst prognosis, with a 5-year survival rate of 58%, although death from pulmonary causes was uncommon. Comparison of these nonsmoking @entity1 with 137 @entity2631 @entity1 who smoked, seen during the same time period, revealed more frequent and severe obstructive changes in smokers. Smoking @entity1 with @entity358 had more severe disease than nonsmoking @entity1 . The single breath diffusing capacity for @entity1223 was significantly decreased in the @entity1 who smoked compared with the nonsmokers. These data confirm that @entity358 are common in @entity1 with @entity785 including @entity4067 . Smoking appears to have an additive deleterious effect on pulmonary function and should be strongly discouraged.
