Preincisional local infiltration of XXXX at the trocar site versus intravenous @entity1340 for @entity158 control after laparoscopic cholecystectomy.

@entity1 @entity1340 @entity3522 @entity1219 @entity158 @entity282 @entity1209
STUDY OBJECTIVE: To compare the effects of preoperative intravenous (IV) @entity1340 and preoperative @entity1340 infiltration of trocar sites on @entity282 and @entity1209 ( @entity1209 ) after laparoscopic cholecystectomy. DESIGN: Prospective, randomized study. SETTING: Operating room, recovery room, and surgical ward. @entity1 : 70 ASA physical status 1 and 2 @entity1 , aged 20-70 years, scheduled for elective laparoscopic cholecystectomy. INTERVENTIONS: In Group I, @entity1 received IV 2.0 mg/kg of @entity1340 ; in Group II, trocar insertion points were infiltrated with 2.0 mg/kg of @entity1340 in 20 mL of 0.9% @entity1219 . MEASUREMENTS: @entity158 scores, sedation scores, postoperative analgesic requirement, and @entity1209 were recorded at 0 and 30 minutes and one, three, 6, 12, and 24 hours. At 30 minutes and one hour, @entity158 localization (incisional or diffuse abdominal) was also recorded. MAIN RESULTS: Visual analog scale scores at 30 minutes were significantly lower in Group II [3 (0-7)] than Group I [6 (3-8)] (P < 0.001). In Group I, 91.4% of @entity1 received @entity3522 , while 68.6% of Group II @entity1 received @entity3522 (P = 0.002). The time to first analgesic requirement was significantly lower in Group II (P = 0.004). At the 30-minute measurement time, a significant difference was recorded between the groups in incisional @entity158 (P < 0.001). There was also a significant difference between groups in the frequency of @entity1209 . CONCLUSIONS: Trocar site infiltration of @entity1340 improves early @entity282 and decreases @entity1209 .
