Increased defibrillator therapies during XXXX season in @entity1 without @entity683 vaccines.

@entity1 @entity683 @entity1002 @entity299
BACKGROUND: The association between @entity683 vaccination and @entity299 ( @entity299 ) therapies during @entity683 season is not known and is described in this study. Understanding this association is important since reduction in @entity299 therapies during @entity683 season via use of @entity683 vaccination would benefit @entity1 physically and psychologically. METHODS: @entity1 presenting to the Sunnybrook Health Sciences Center @entity299 clinic between September 1st, 2011 and November 31st, 2011 were asked to complete a survey evaluating their use of the @entity683 vaccine. The number of @entity1 with any @entity299 therapy and the total number of @entity299 therapies in the six months before and the three months during the 2010-2011 @entity683 season were determined. Poisson regression analysis was employed to assess differences in the average number of @entity299 therapies received during the @entity683 season based on vaccine status (vaccinated vs. unvaccinated). The analysis was repeated after limiting the cohort to @entity1 with a left ventricular ejection fraction  <=35%. RESULTS: A total of 229 @entity1 completed the survey, 78% of whom received the @entity683 vaccine. Four @entity1 had more than one @entity299 shock during the study period. Electrical storm was rare (n=2). A trend toward more @entity299 therapies (unadjusted incident rate ratio (IRR)=3.2; P=0.07) and appropriate @entity299 shocks (unadjusted IRR=9.0; P=0.17) was noted for unvaccinated compared to vaccinated @entity1 . This association persisted when analysis was limited to @entity1 with a left ventricular ejection fraction  <=35% (all @entity299 therapies: unadjusted IRR=5.8; P=0.045; adjusted IRR=2.6; P=0.33). No @entity1 who received the @entity683 vaccine, and had a reduced ejection fraction, received an approprite @entity299 shock during @entity683 season (unadjusted P<0.002). CONCLUSION: A trend toward more @entity299 therapies during @entity683 season was observed in @entity1 who did not receive the @entity683 vaccine compared to those who did. The association was stronger in @entity1 who received appropriate @entity299 shocks and in @entity1 with @entity1002 . Further work to confirm these findings is recommended.
