Timing of Percutaneous Coronary Intervention in Troponin-negative @entity1 With XXXX Without Persistent ST-segment Elevation: Preliminary Results and Status Quo in German Chest Pain Units.

@entity1 @entity1187 @entity1459 @entity662
OBJECTIVE:: Management of @entity1187 without persistent ST-segment elevation (NSTE-ACS) and @entity1459 ( @entity1459 ) remains challenging. The study aimed to analyze the current management of @entity1459 @entity1 in German @entity662 units focussing on the different time lines of invasive strategy. METHODS:: A total of 1400 @entity1459 @entity1 admitted to a certified @entity662 unit were enrolled. Analyses of high-risk criteria with indication for invasive management and of 3-month clinical outcomes were performed by subgrouping @entity1459 @entity1 to immediate and early invasive (<8 hours), early elective invasive (8-24 hours), late elective invasive (24-72 hours) strategy, and without percutaneous coronary intervention (PCI). RESULTS:: Coronary angiography was performed in 60.6% of the @entity1459 @entity1 , whereas PCI was necessary in 37%. Only 1.4% of the @entity1459 @entity1 obtained immediate PCI within the first 120 minutes. In 16.9%, @entity1 received PCI within the first day of hospitalization or even within the first 8 hours after admission in another 7.7%, although the Global Registry of Acute Coronary Events (GRACE) score at admission was below 140. In the remaining 12.4% of the @entity1459 @entity1 , PCI was performed within 24-72 hours after admission. Those @entity1 exhibited a higher prevalence of secondary risk markers than those with conservative treatment regimen. CONCLUSIONS:: To date, almost two-third of @entity1459 @entity1 at intermediate to high risk receive rapid invasive regimen within the first 24 hours after admission. Oncoming studies will have to analyze its overall guideline-adherence and resulting differences in major adverse events.
