Quality of Life in XXXX Suffering from Active Exudative Age-Related Macular Degeneration: The EQUADE Study.

@entity1 @entity1020 @entity227 @entity7
PURPOSE: @entity1020 ( @entity1020 ) is the main cause of @entity227 in the elderly population. With the use of anti- @entity7 , the visual outcomes of exudative @entity1020 @entity1 have been improved. This study was aimed at assessing the quality of life (QoL) of exudative @entity1020 @entity1 treated with ranibizumab and at determining its drivers in a real-life setting. METHODS: We performed a national, cross-sectional, observational survey based on questionnaires sent to members of French associations relative to @entity1020 between December 2012 and March 2013. @entity1 suffering from exudative @entity1020 with at least one intravitreal injection of ranibizumab within the last 6 months were included. Demographics, @entity1020 characteristics, visual acuity (VA) and past and ongoing treatments were collected. The 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) was self-administered. A multivariate model was used to identify QoL drivers. RESULTS: 416 questionnaires fulfilled the complete criteria for both QoL and cost analyses. The mean age of exudative @entity1020 @entity1 was 78.0 years and bilateral involvement was reported in 60.4%. The overall mean QoL score was 53.4. Mental health, driving and role difficulties were the most widely affected domains. After bivariate analyses, long-term illness status, worse VA and higher number of unpaid aids were associated with worse QoL, with odds ratios of 2.4, 5.2 and 11.6, respectively. The mean cost per year and per @entity1 was 1,741 EUR. The main components of costs were aids and services and the purchase of visual equipment. CONCLUSIONS: The main predictors of QoL in exudative @entity1020 @entity1 treated with ranibizumab are VA outcomes, home healthcare and social services provided to the @entity1 .    2015 S. Karger AG, Basel.
