Central corneal thickness in primary angle closure and open XXXX .

@entity1 @entity725 @entity2840 @entity227 @entity5494 @entity726 @entity2747
PURPOSE: To quantitatively analyze @entity2840 ( @entity2840 ) in @entity1 with primary @entity2747 (PACG) and @entity725 ( @entity725 ), and to evaluate its correlation with severity of @entity726 . METHODS: In this retrospective study, records of @entity1 with previously diagnosed @entity725 or PACG at a tertiary @entity726 service were reviewed. @entity2840 was measured by ultrasound pachymetry. @entity5494 ( @entity5494 ) on @entity227 ( @entity227 ) testing was recorded for @entity726 severity determination. @entity2840 and age- and sex-adjusted @entity2840 were compared among the study groups using Student's t-test and analysis of covariance (ANCOVA), respectively. Univariate and multivariate regression models were used for correlation of age, @entity5494 and @entity2840 . RESULTS: A total of 115 @entity1 with PACG, 215 with @entity725 , and 100 normal controls were included with mean age of 64.1    10.4, 59.9    10.5, and 62.04    10.80 years, respectively. @entity2840 was thicker in PACG eyes (545.5    46.1  m) as compared to @entity725 eyes (531.7    37.3  m) and controls (531.0    38.3  m) even after age and gender adjustment (ANCOVA, P = 0.05). @entity2840 was found to decrease with increasing age only in the @entity725 group (b = -0.57, P = 0.01). Disease severity ( @entity5494 of @entity227 ) was significantly and inversely correlated with @entity2840 in both @entity725 and PACG eyes (b = 1.89, P = 0.02; and b = 1.38, P = 0.04, respectively) after age and sex correction. CONCLUSION: PACG eyes had thicker @entity2840 as compared to @entity725 and normal healthy eyes in Iranian subjects. Severity of the disease was inversely correlated with @entity2840 in eyes with both @entity725 and PACG.
