@entity158 control in laparoscopic gynecologic surgery with/without preoperative (preemptive) XXXX @entity1372 injection: a randomized study.

@entity1 @entity14340 @entity1372 @entity6882 @entity158 @entity282
OBJECTIVE: To determine the effectiveness of preoperative @entity14340 @entity1372 injection for @entity158 relief after laparoscopic gynecologic surgery. MATERIAL AND METHOD: A prospective double-blind, randomized study was conducted in 268 @entity1 who underwent laparoscopic gynecologic surgery at Vajira Hospital between November 1, 2010 and March 31, 2011. The @entity1 were randomly allocated into two groups to receive either single intravenous 40 mg @entity14340 (treatment group; n = 133) or normal saline (control group; n = 135) 30 min before surgery. The degree of @entity282 was assessed every 2 h in the first 8 h postoperation, then every 4 h until completion of 24 h by using a verbal rating scale. Total consumption of @entity6882 over a 24-h period and the adverse events relevant to @entity14340 @entity1372 were also recorded. RESULTS: Mean @entity158 scores at all measured times in the treatment group were insignificantly lower than those in the control group (p = 0.106). The mean 24-h postoperative @entity6882 consumption in the treatment group was significantly lower compared to that in the control group (26.3 +/- 28.1 mg and 39.1 +/- 34.6 mg, respectively, p = 0.001). The proportion of @entity1 requiring @entity6882 in the treatment group was significantly lower than that in the control group (58.6% and 70.3%, respectively, p = 0. 045). No serious adverse events were observed in both groups. CONCLUSION: Preoperative @entity14340 @entity1372 significantly reduced postoperative @entity6882 requirement and consumption, while insignificantly declined the @entity158 scores. Serious adverse events were not encountered
