The adjuvant role of two cycles of MOPP and low-dose lung irradiation in stage IA through IIB XXXX : preliminary results.

@entity1 @entity978 @entity1073 @entity66
Fifty-eight laparotomy-staged I and II @entity1 with upper torso presentations of @entity978 and 8 @entity1 with lymphangiogram-staged @entity66 were treated with radiotherapy alone or with 2 cycles of MOPP and radiotherapy. @entity1 with @entity66 with either no mediastinal or only small mediastinal disease without hilar involvement and with no "B" symptoms were treated with mantle radiotherapy alone. @entity1 with large mediastinal masses or hilar disease were treated with 2 cycles of MOPP followed by @entity1073 and low dose lung irradiation. Those for whom "B" symptoms were the only adverse prognostic feature received 2 cycles of MOPP and mantle radiotherapy. @entity1 with @entity66 were treated with radiotherapy alone if the disease was limited to the pelvis. Those with more extensive disease received 2 cycles of MOPP prior to radiotherapy. The 4-year survival for all 66 @entity1 was 97%. The corresponding disease-free and freedom from second relapse figures were 77% and 92%. Survival for the @entity1 with unfavorable presentations who received 2 cycles of MOPP and radiotherapy was 100%. It was 92% for the group with favorable presentations who were treated with radiotherapy only.
