XXXX . A report of the clinicopathological features and treatment of seventy-eight cases.

@entity1 @entity511 @entity1492 @entity421 @entity258
@entity511 is a highly malignant variant of @entity511 . Approximately 11 per cent of @entity511 can be expected to dedifferentiate into more anaplastic lesions. In this report, we analyze the clinicopathological features and treatment of seventy-eight lesions of this type. The ages of the @entity1 ranged from nineteen to eighty-two years (average, 54.6 years). The cartilaginous precursor was central in most @entity1 . Eleven of the lesions developed in the site of a previously resected @entity258 . Dedifferentiation was from @entity258 to @entity421 in forty-two @entity1 , to @entity1492 in thirty-three, and to malignant (fibrous) histiocytoma in three. Perforation of the cortex and a soft-tissue mass were found in most of the @entity1 . Widespread metastatic disease within two years after resection was a frequent finding. The over-all five-year-survival rate was 10.5 per cent. Any potential for a "cure" is related to early diagnosis and adequate surgical treatment by amputation or resection.
