XXXX and aging: clinical and hormonal factors.

@entity1 @entity323 @entity251 @entity11539 @entity4611 @entity6126 @entity731 @entity250
A cross-sectional study of 216 impotent @entity1 aged 40 to 79 years (mean age 60.9 years) was conducted to determine if there are age-related changes in clinical and hormonal parameters in an impotent population. There was a slight increase in the degree of @entity250 with age, with @entity323 occurring in a larger percent of the 60- and 70-year-olds than in the younger @entity1 (41% vs 27% for the 40 year olds, P less than .05). No @entity1 above the age of 70 years reported any full erections, even of short duration. In contrast, reported levels of libido did not vary significantly with age. Abnormal penile Doppler studies diagnostic of @entity11539 were found in 17.8% of the @entity1 tested, and an additional 17.8% were found to have evidence suggestive of a vascular etiology. These abnormal vascular findings were associated with an extremely high prevalence of clinically apparent @entity731 in this population. In 22.9% of the subjects, an abnormal vascular response was found only on exercise, ie, a "pelvic steal", which only occurred above the age of 50 years. There was a marked age-related alteration in the concentration of @entity251 (T) and bioavailable @entity251 (BT), but no statistically significant change in the levels of gonadotropins with age. An increase in the prevalence of @entity6126 with age was found, which suggested an increasing prevalence of hypothalamic @entity4611 in this @entity1 group. For both vascular and hormonal changes (such as low T and BT), the greatest changes appear to occur after the age of 50.(ABSTRACT TRUNCATED AT 250 WORDS)
