Effect of CPAP on New Endothelial Dysfunction Marker, @entity22968 , in XXXX With Obstructive Sleep Apnea.

@entity22968 @entity1 @entity455 @entity384 @entity409 @entity27
UNASSIGNED: @entity27 ( @entity27 ) is associated with increased cardiovascular (CV) morbidity and mortality. @entity22968 is a surrogate @entity409 marker that may be associated with CV risk factors. In this study, we tested whether serum @entity22968 is a biomarker for @entity27 . Serum @entity22968 levels were measured at baseline in 40 @entity1 with @entity27 and 40 healthy controls and after 3 months of continuous positive airway pressure (CPAP) treatment in the @entity1 with @entity27 . All @entity1 were evaluated by full polysomnography. @entity384 ( @entity384 ) and carotid intima media thickness (cIMT) were measured in all @entity1 . @entity22968 levels were significantly higher in @entity1 with @entity27 than in healthy controls. After adjusting confounders, @entity22968 was a good predictor of @entity27 . @entity22968 levels correlated with @entity27 severity (measured by the @entity27 [ @entity27 ]). After 3 months of CPAP treatment, @entity22968 levels significantly decreased. @entity22968 levels were significantly and independently correlated with cIMT and @entity384 after multiple adjustments. The cIMT and @entity384 also had significant and independent correlation with @entity27 . @entity22968 might be a useful marker for the predisposition of @entity1 with @entity27 to @entity455 .
