Claudin-7-positive synchronous spontaneous @entity1419 , @entity420 and XXXX in a Bearded dragon ( @entity34450 ).

@entity5 @entity201 @entity1419 @entity34450 @entity2915 @entity652 @entity420
In this study, synchronous spontaneous, independent liver and @entity5 were detected in a Bearded dragon ( @entity34450 ). The @entity5 consisted of @entity1419 as well as in situ @entity420 and two @entity652 . The biliary epithelial cells and the @entity201 showed @entity2915 -immunoreactivity for claudin-7. The gallbladder epithelial cells, its @entity652 and @entity420 showed basolateral cross-reactivity for claudin-7. We think that the humanised anti-claudin-7 antibody is a good marker for the detection of different primary cholangiocellular and @entity5 in Bearded dragons. The cholangiocytes, the @entity201 , the endothelial cells of the liver and the epithelial cells and @entity5 all showed claudin-5 cross-reactivity. The humanised anti-cytokeratin AE1-AE3 antibody showed cross-reactivity in the biliary epithelial cells, @entity201 cells, epithelial cells and @entity5 cells of the gallbladder. It seems that this humanised antibody is a useful epithelial marker for the different neoplastic lesions of epithelial cells in reptiles. The humanised anti-a-smooth muscle actin (a-SMA) antibody showed intense cross-reactivity in the smooth muscle cells of the hepatic vessels and in the muscle layer of the gallbladder. The portal myofibroblasts, the endothelial cells of the sinusoids and the stromal cells of the @entity201 and @entity5 were positive for a-SMA. The antibovine anti-vimentin and humanised anti-Ki-67 antibodies did not show crossreactivity in the different samples from the Bearded dragon.
