Local allergic nasal reactions convert to classic XXXX : a long-term follow-up.

@entity1 @entity566 @entity4186 @entity56
BACKGROUND: There is poor knowledge about the evolution of the negative skin test in local @entity566 over time. Does the negative skin test of @entity1 with @entity566 remain negative permanently or does it become positive? METHODS: We describe our long-term observation concerning the evolution of the negative skin test over time. This is a retrospective, follow-up study using data from the medical records of a group of @entity1 with local @entity566 . A total of 42 @entity1 aged between 3 and 70 years (median age: 31.5 years) were studied. The duration of follow-up varied from 1 to 27 years. Skin tests were performed using the skin-prick test and intracutaneous techniques for pollen, molds, mites, feathers (goose and @entity4186 ) and animal danders. Nasal provocation tests were conducted with the same allergens. Additionally, specific IgE in 17 @entity1 was measured by enzyme allergosorbent test. RESULTS: During the period of observation, the negative skin test reactions converted into positive reactions in 17 @entity1 (40%). In addition to the negative skin reactions, 55% of the @entity1 also presented positive skin reactions. The conversion rate was higher in @entity1 and adolescents than in adults. In 4 @entity1 , conversions occurred >7 years after the initial examination. Specific IgE was negative in all but 2 @entity1 , in whom the conversion in the skin test was accompanied by a switch from negative to positive specific IgE. CONCLUSION: Conversions from local to @entity56 appear to be a common phenomenon.
