Abdominal Visceral Fat Accumulation Measured by Computed Tomography is Associated with an Increased Risk of XXXX .

@entity1 @entity101 @entity6 @entity2299 @entity28 @entity2690 @entity5990 @entity8586 @entity1386 @entity165
BACKGROUND: Visceral adiposity is a strong determinant of @entity2690 resistance, which decreases @entity8586 response sensitivity, and increases @entity165 saturation in the gallbladder bile; thus, it potentially relates to @entity5990 development. We aimed to investigate whether visceral fat measured by computed tomography (CT) is a risk factor for @entity5990 . METHODS: A cohort of 717 @entity1 undergoing CT and ultrasonography was analyzed. The associations between body mass index (BMI), @entity1386 ( @entity1386 ) area, @entity1386 ( @entity1386 ) area, and @entity5990 were analyzed adjusted for age, sex, @entity101 , @entity6 , and @entity2299 . RESULTS: In multivariate analysis, @entity5990 was significantly associated with @entity1386 and @entity1386 areas for both categorical data and trend (P for trend <0.001, 0.009), but not BMI. Among @entity1 with BMI <25, @entity5990 remained significantly associated with @entity1386 area (P for trend 0.021) and @entity1386 area (P for trend 0.005). Interactions between the @entity28 indices and being elderly on the risk of @entity5990 were found; specifically BMI (P=0.005), @entity1386 (P<0.001), and @entity1386 (P=0.154). A significant association between all @entity28 indices and @entity5990 was seen in @entity1 aged <65 but not among those aged >= 65. However, no significant association was noted between the @entity28 indices and sex. CONCLUSIONS: CT-measured adipose tissue, rather than BMI, was a better predictor for risk of @entity5990 . This finding   applies to younger   @entity1 or even those with normal body weight,   suggesting the importance of abdominal visceral fat accumulation in the development of @entity5990 .
