XXXX arising after endoscopic mucosal resection for @entity957 of the esophagus.

@entity1 @entity135 @entity1496 @entity5 @entity957 @entity1721 @entity418
BACKGROUND AND STUDY AIMS: It is well known that @entity1 with @entity135 often have synchronous or metachronous @entity957 of the esophagus. However, the prevalence of subsequent @entity135 in @entity1 with early-stage @entity418 is still unknown. The aims of this study were to analyze the frequency of metachronous @entity135 after endoscopic mucosal resection (EMR) for @entity418 and to investigate whether minute @entity1496 -unstained areas, often associated with @entity957 , would be an index for metachronous @entity135 . @entity1 AND METHODS: 99 @entity1 with @entity1721 who underwent EMR were studied. Based on the @entity1496 -staining pattern at initial EMR, they were categorized into those with uniform (group U) and scattered (group S) types of background mucosa. @entity1 were monitored endoscopically and otolaryngologically (group U, median 46 months, range 12-83 months; group S, median 44 months, range 13-80 months). RESULTS: In total, 5/99 @entity1 (5.1 %) were found to have metachronous @entity135 during the follow-up, including 4/20 @entity1 (20 %) in group S. In three cases laryngeal or @entity5 was found by endoscopic examination. The cumulative proportion of metachronous @entity135 -free subjects was significantly lower in group S than group U (P = 0.0007). CONCLUSIONS: Among @entity1 who undergo EMR for @entity418 , those with scattered-type @entity1496 staining of the background mucosa have an increased risk of metachronous @entity135 , and should therefore be closely observed. Careful endoscopic observation led to early detection of laryngeal and @entity5 .
