Religiosity, spirituality, and XXXX in African-Americans at risk for having a hereditary cancer predisposing gene mutation.

@entity1 @entity308 @entity146 @entity5 @entity5345 @entity458
@entity458 has been observed among @entity1 at increased risk for @entity5 . Researchers consider religiosity and spirituality (RS) to be positive coping mechanisms associated with @entity146 . Relatively little is known about the impact of RS on genomic health issues. The objectives of our study were: (1) describe the prevalence of RS and @entity308 and (2) explore how RS relates to @entity458 in a cohort of individuals with a > or =25% prior probability of a genetic predisposition to @entity5 . @entity1 (n = 99) were drawn from an African-American, Louisiana-based kindred with a mutation at the @entity5345 locus. This analysis reports findings from a survey assessing RS and the use of three types of religious coping styles: collaborative, self-directing, and deferring. Clinically significant @entity308 were relatively high (27%); with females (33%) more likely than males (17%) to report symptoms (P < 0.01). The majority of @entity1 reported being highly religious. The most commonly employed religious problem solving style used by @entity1 was collaborative (X=22.9; SD=5.8) versus self-directing (X=12.8; SD = 5.1) and deferring (X=19.9; SD = 6.3). We did not observe significant associations between RS indicators and @entity458 , nor did we observe appreciable differences related to gender or risk perception. Although RS beliefs and practices are important for many African-Americans, we did not find evidence that indicators of self-reported RS are associated with @entity458 prior to genetic counseling and testing.
