Transcranial magnetic stimulation after XXXX .

@entity1 @entity64 @entity713 @entity9808 @entity854
OBJECTIVES: The objective of this study was to assess the sensitivity of motor-evoked potentials (MEPs) elicited by @entity9808 ( @entity9808 ) in demonstrating the possible subclinical impairment of the corticospinal pathway after recovery, in @entity1 with a clinical history of @entity64 ( @entity64 ) due to a single lacunar infarct detectable by magnetic resonance imaging (MRI). METHODS: MEPs were recorded from the first dorsal interosseous muscle of 20 healthy subjects and 40 @entity1 , 6 months or more after @entity64 onset. @entity1 were evaluated clinically by means of the @entity64 scale, the Medical Research Council (MRC) scale and the Barthel Index. The @entity1 with full hand strength recovery and the normal controls were also tested by means of the 9-hole peg test. RESULTS: Motor threshold (MT), MEP amplitude and @entity713 ( @entity713 ) of the affected side were significantly different from those of the normal side and of the control subjects. MT, MEP amplitude and @entity713 obtained after stimulation of the affected hemisphere were significantly correlated with the MRC scale values of the affected hand. Eighty-six percent of @entity1 with persistent hand strength deficit showed @entity854 . In 21 @entity1 with complete clinical recovery, a significant increase in MT and decrease in MEP amplitude on the affected side were observed. CONCLUSIONS: After @entity64 , neurophysiological changes may persist despite complete clinical recovery. @entity9808 represents a sensitive tool that enables to demonstrate objectively the clinical and subclinical impairment of the corticospinal pathway.
