Pregnancy-associated esterase in sera of XXXX .

@entity1 @entity18617 @entity36434 @entity6201 @entity6599 @entity2975 @entity27358
Baboon serum samples were resolved by starch gel electrophoresis and @entity2975 gradient gel electrophoresis and stained with @entity6201 substrates for esterase activity. An esterase that hydrolyzed @entity36434 in preference to @entity18617 was found in very high activities in some individuals but not others. It migrated just cathodal of the albumin band in starch gels. In @entity2975 gradient gels, it co-migrated with albumin and had an apparent molecular weight of approximately 65,000 daltons. Electrophoretic analysis by gel electrophoresis of random serum samples from male and female @entity6599 indicated that this esterase was present only in the sera of pregnant @entity6599 . Further investigation of serial samples collected from carefully monitored @entity6599 confirmed that the amount of activity of this esterase was correlated with stage of pregnancy. Therefore, it was named @entity27358 ( @entity27358 ). @entity27358 was detectable by gel electrophoresis and chromogenic staining techniques as early as day 30 of pregnancy; its activity gradually increased with progressive pregnancy and reached maximum activity near full term (182 days). Soon after parturition, the activity of @entity27358 decreased rapidly and was not detected in maternal sera by day 14 postpartum. No evidence of @entity27358 was detected in sera of pregnant @entity1 .
