[Effects of XXXX alone or exercise combined on capillarization of @entity35 gastrocnemius muscle and its mechanism].

@entity2478 @entity2295 @entity12186 @entity519 @entity194 @entity35 @entity6667
OBJECTIVE: To study the effects of @entity519 and @entity519 -combined-exercise on @entity2478 and @entity6667 ( @entity6667 ) and its receptor @entity12186 of skeletal muscle in @entity35 . METHODS: Myosin-ATPase histochemistry was used to assay the size and @entity2478 of skeletal muscle. @entity6667 and its receptor @entity12186 were studied by immunohistochemistry. RESULTS: Five-week @entity519 (simulated 5,000 m altitude) resulted in a decrease in cross-sectional area of skeletal muscle fiber and an increase in @entity2478 ( @entity2478 ), but the capillary/fiber ratio (C/F) remained unchanged. After 5-week-exercise at high altitude (1 h/d, 6 d/w), the muscle fibers did not undergo @entity194 . At the same time, @entity2478 and C/F were increased. @entity6667 protein was found primarily in the matrix between muscle fibers; @entity6667 receptor- @entity12186 was shown mainly in endothelial cells of capillary. @entity6667 was more strongly stained in the skeletal muscle of @entity519 -combined-exercise @entity35 than the other two groups. CONCLUSION: @entity519 itself can not induce @entity2295 , while @entity519 -combined-exercise @entity35 show capillary proliferation in skeletal muscle. @entity6667 and its receptor might play roles in this process.
