Diffuse XXXX : characteristics and prognosis.

@entity1 @entity8 @entity64 @entity2758 @entity16 @entity2702 @entity519 @entity204 @entity867
OBJECTIVE: To study the clinical characteristics and prognosis of @entity1 with diffuse @entity2702 ( @entity2758 ). DESIGN: Retrospective chart review of all @entity1 (n = 16) with @entity2702 seen at Yale New Haven Hospital, Johns Hopkins Hospital, and St. Michael's Hospital. Up-to-date follow-up information was obtained in all living @entity1 . RESULTS: All @entity1 were severely @entity519 . @entity16 ( @entity64 or @entity867 ) had occurred in 70% of @entity1 by the time of diagnosis. During the follow-up period (mean, 6 years), three @entity1 died and two others developed new @entity16 . One of the @entity204 occurred perioperatively during lung transplantation. All @entity1 underwent transcatheter embolotherapy of any large pulmonary @entity2758 . A selected group underwent pulmonary flow redistribution, a novel technique. Oxygenation did not improve significantly with embolotherapy of the larger @entity2758 , but there was a small significant improvement in those @entity1 who underwent pulmonary flow redistribution. The majority (85%) of the living @entity1 are currently working or studying full-time. CONCLUSIONS: @entity1 with @entity2702 are at increased risk of @entity16 . Transcatheter embolotherapy does not significantly improve the profound @entity519 , but it may reduce the risk of @entity16 . Antibiotic prophylaxis is recommended for bacteremic procedures to prevent @entity867 . These @entity1 can live for many years and lead productive lives. We do not recommend lung transplantation because survival with disease is difficult to predict and we have observed a perioperative @entity8 .
