Superficial XXXX : clinicopathologic aspects and involvement of extracellular matrix proteoglycans.

@entity1 @entity32 @entity1333 @entity5 @entity3468 @entity439 @entity24319 @entity2849 @entity130 @entity7597
The distribution of proteoglycans in 21 temporal and two ulnar @entity2849 was studied immunohistochemically. A history of @entity130 was elicited in six cases, and 16 of the lesions were pulsatile. The clinical diagnosis was @entity439 or cyst in 18 @entity1 , possible @entity3468 in two @entity1 , @entity5 in one @entity1 , and unknown in the remaining @entity1 . Histologically, there was a prominent myxoid neointimal response in the walls of each interrupted artery. The remnant arterial segment was often inconspicuous. Prominent smooth muscle cell proliferation and granulation tissue response with @entity32 led to misdiagnosis of @entity5 or @entity1333 , respectively, in 11 cases. Immunohistochemical staining for proteoglycans demonstrated abundant, diffuse @entity24319 in interrupted wall segments. @entity7597 was confined to collagenized and vascularized areas. In some portions of medial disruption, in which angiogenesis was prominent, decorin was expressed within endothelial cells of neocapillaries. These findings demonstrate that superficial @entity2849 may be mistaken clinically and pathologically for unrelated entities. The immunohistochemical studies confirm that @entity24319 is upregulated in areas of tensile stress. In addition, the presence of endothelial expression of decorin supports the concept of decorin's involvement in angiogenesis.
