What parameters from @entity419 PET/CT are useful in evaluation of XXXX ?

@entity1 @entity419 @entity75 @entity5 @entity378 @entity774
PURPOSE: Prior studies have suggested that @entity419 PET/CT can help characterize @entity75 and differentiate adrenal metastases from benign lesions. The aim of this study was to assess the value of @entity419 PET/CT for the differentiation of malignant from benign @entity75 . METHODS: This retrospective study included 85 @entity1 (47 @entity1 and 38 @entity1 , age 63.8        10.8  years) who had undergone @entity419 PET/CT (60  min after injection 300  -  370  MBq @entity419 ; Biograph 64 scanner) for evaluation of 102 nonsecreting @entity774 . For semiquantitative analysis, the maximum standardized uptake value (SUVmax), adrenal to liver (T/L) SUVmax ratio, mean CT attenuation value and @entity5 diameter were measured in all lesions and compared with the pathological findings. RESULTS: @entity5 (68  % of evaluated @entity5 ) had a significantly higher mean SUVmax (13.0        7.1 vs. 3.7        3.0), a higher T/L SUVmax ratio (4.2        2.6 vs. 1.0        0.9), a higher CT attenuation value (31.9        16. 7  HU vs. 0.2        25.8  HU) and a greater diameter (43.6        23.7  mm vs. 25.6        13.3  mm) than benign lesions. The false-positive findings were @entity378 and @entity5 . Based on ROC analysis, a T/L SUVmax ratio >1.53, an adrenal SUVmax >5.2, an attenuation value >24  HU and a @entity5 diameter >30  mm were chosen as the optimal cut-off values for differentiating @entity5 . The areas under the ROC curves for the selected cut-off values were 0.96, 0.96, 0.88 and 0.77, respectively. A multivariate logistic regression model revealed that the T/L SUVmax ratio was an independent prognostic factor for @entity5 (p   <   0.001); a CT attenuation value of >25 HU and a @entity5 diameter >30  mm had no additional individual importance in the diagnosis of @entity5 . CONCLUSION: Using a T/L SUVmax ratio >1.53 and an adrenal SUVmax >5.2 in @entity419 PET/CT led to high diagnostic sensitivity, specificity and negative predictive value for characterizing @entity5 . The diagnostic accuracies of the two parameters were comparable, but T/L SUVmax ratio was an independent predictor of @entity5 .
