Liver transplantation for XXXX : a long-term clinicopathologic study.

@entity1 @entity295 @entity63 @entity5 @entity22301 @entity991 @entity409 @entity29 @entity813 @entity204 @entity775
The course and outcome of @entity1 after liver transplantation (LT) for @entity991 ( @entity991 ) are still debated. Our purpose is to define retrospectively, the post-LT clinicopathologic findings seen in 51 @entity991 @entity1 with a follow-up of 2 to 14 years. Of the total 51 @entity1 , 16 with native liver @entity22301 (XGC) had median graft and @entity1 survival of 573 and 835 days, respectively compared with 2489 and 2794 days, respectively, in 35 @entity1 without XGC. Perioperative complications resulted in 9 early @entity204 (day 0 to 52). Of the remaining 42 @entity1 , 6 had recurrent @entity991 (R- @entity991 ) with typical histologic and cholangiographic findings, 12 had @entity409 -not otherwise specified with histology of @entity775 , 3 had chronic rejection, 4 had @entity63 , and 17 had no recurrence. The presence of @entity29 , total @entity63 time of > or =11 hours, recipient-donor ABO and HLA Class I and II matches, and the type of immunosuppression did not affect the post-LT outcome. Recipient-donor gender mismatch was more common in R- @entity991 than in the nonrecurrent group (P=0.045). Post-LT @entity5 were significantly more common in the nonrecurrent cases compared with all others combined (P=0.031) and caused @entity204 in 4. The majority of @entity204 (11/13) in other groups were due to @entity295 complicating @entity813 . In conclusion, allograft @entity409 was seen in 18 (43%) of 42 long-term post-LT @entity991 @entity1 , with progression in 5 of 18 @entity1 . Features of @entity991 were seen in 6 (33%) of 18. Native liver XGC negatively impacted post-LT graft and @entity1 survival. Increased incidence of @entity5 in the nonrecurrent group may reflect overimmunosuppression in those @entity1 .
