Robotic radiosurgery for the treatment of medium and large XXXX .

@entity1 @entity548 @entity5 @entity726 @entity1103 @entity2184 @entity320
UNASSIGNED: The aim of the study was to analyze the local efficacy and eye retention rate after frameless, image-guided robotic radiosurgery against @entity2184 . A total of 217 @entity1 , mostly with medium and large unilateral uveal @entity320 (3% small, 62% medium, and 35% large) were treated. The median age was 64 years (range 21-95 years). All @entity1 underwent a single-session procedure beginning with retrobulbar anesthesia, followed by MRI and computerized tomography scanning to generate the treatment plan. The @entity5 dose was 18-22   Gy (mean, 20.3   Gy) prescribed to the 70% isodose line. Follow-up occurred at 3, 6, 12, and 18 months and yearly thereafter with clinical, ultrasound, and MRI studies. The median follow-up time was 26.4 months. All @entity1 were treated in the frameless setup within 3   h. The actuarial 3- and 5-year eye retention rates were 86.7 and 73%, respectively. Local control at 3 and 5 years was 87.4 and 70.8%, respectively. Serviceable vision was maintained in 30.9% of @entity1 at last follow-up. Treatment-induced @entity726 developed in 33 @entity1 at a median 20.8 months (range, 5.8-54.0 months). Other adverse effects were @entity548 (26 @entity1 ) and @entity1103 (seven @entity1 ). Frameless, single-session, image-guided robotic radiosurgery is an effective and straightforward treatment option for @entity1 with medium and large @entity2184 that are otherwise difficult to treat.
