Peripheral blood @entity1243 and @entity13490 levels as clinical activity biomarkers in Mexican XXXX @entity1 .

@entity1 @entity650 @entity1356 @entity310 @entity13490 @entity1243 @entity1254 @entity4155 @entity309
OBJECTIVE: To evaluate the association between the clinical activity of @entity309 patients and serum adipocytokines ( @entity1243 , @entity1254 and @entity13490 ) and inflammatory cytokines. METHODS: All @entity309 @entity1 fulfilled ACR 1987 criteria and were treated with DMARDs. Adipocytokine and inflammatory cytokine levels were evaluated using ELISA. RESULTS: 121 @entity1 were included in the study. Stratifying according to DAS28 (low, moderate and high activity), there were significant differences for @entity1243 , @entity13490 , @entity650 and @entity4155 , however, no differences were seen for @entity1254 , @entity310 or @entity1356 . Clinical activity positively correlated with @entity1243 , @entity13490 , @entity4155 and @entity650 levels, but not with @entity1254 , @entity310 or @entity1356 . @entity1254 levels negatively correlated with @entity310 and positively correlated with @entity1356 . @entity1356 positively correlated with @entity650 and negatively correlated with @entity310 and @entity4155 . CONCLUSION: Circulating @entity1243 , @entity13490 , @entity650 and @entity4155 levels positively correlate with @entity309 clinical activity in a manner independent of the subject's BMI. Complex relationships between inflammatory cytokines were observed in @entity309 @entity1 suggesting that other metabolic or inflammatory factors could be involved.
