Neutrophil-to-lymphocyte ratio: could it be used in the clinic as prognostic marker for XXXX ?

@entity1 @entity7158 @entity677 @entity39 @entity5 @entity3 @entity674
BACKGROUND/AIMS: The association between systemic inflammatory response and @entity5 biology has been well documented over the last decade. The aim of this study is to investigate the prognostic role of neutrophilto- lymphocyte ratio (NLR) in @entity674 ( @entity674 ). METHODOLOGY: A prospectively recorded database of 67 @entity1 who underwent surgical resection for @entity677 was reviewed. High and low NLR were defined with respect to the sample median, which was 1.92. Demographical, clinicopathological, and surgical characteristics were analyzed as well as disease free survival (DFS) rates according to NLR classification. RESULTS: We observed better disease free survival rates in @entity1 with low NLR compared to @entity1 with high NLR (85.7% and 69%, respectively; p=0.037). Estimated five-year overall and disease free survival rates were 95.1% and 78.7%, respectively. In univariate analysis @entity7158 , @entity5 size, mitotic rate, presence of @entity39 , lymph node @entity3 , surgical margin status, risk category and NLR were associated with DFS. On multivariate analysis sarcomatosis (HR: 30.455), surgical margin status (HR: 4.228) and @entity39 (HR: 4.415) were found as independent prognostic factors for DFS. CONCLUSIONS: NLR can give information about inflammatory status, @entity5 aggressivity and prognosis in @entity677 @entity1 . It could be a new prognostic factor for @entity677 @entity1 .
