Primary extranodal soft-tissue XXXX with abundant immunoglobulin inclusions mimicking @entity4618 : a case report.

@entity1 @entity1071 @entity706 @entity5 @entity20392 @entity1892 @entity4618 @entity158
INTRODUCTION: Immunoglobulin inclusions are found in B-cell neoplasms as well as in crystal-storing histiocytosis associated with B-cell @entity1071 . At times, the deposits may be so profound as to obscure the diagnosis and may even lead to misdiagnosis. We report one case of low-grade extranodal @entity706 with abundant immunoglobulin inclusions and emphasize the need for immunophenotyping and molecular assay to make the right decision in diagnosis. To the best of our knowledge, this is the first report of extranodal @entity1892 with abundant intracellular immunoglobulin accumulation. CASE PRESENTATION: A 62-year-old Asian @entity1 from China presented with a 13-year history of a right shoulder mass with recent ongoing @entity158 . A @entity20392 located in the posterior muscles of the neck was suggested by magnetic resonance imaging, and extended local excision was performed. A biopsy, however, revealed large, isolated rhabdoid cells in a diffuse pattern with mild atypia and eosinophilic cytoplasm. @entity706 were interspersed among these cells. The diagnosis was initially suggested to be @entity4618 . The final diagnosis of @entity706 was made after immunohistochemical, ultrastructural and molecular studies. CONCLUSION: We emphasize this histopathologic and immunohistochemical finding because of the potential for confusion with other @entity5 or disorders, such as @entity4618 or crystal-storing histiocytosis.
