Increases in Drug and Opioid XXXX Deaths - United States, 2000-2014.

@entity4521 @entity1 @entity4784 @entity4968 @entity3575 @entity158 @entity284 @entity204 @entity1445 @entity734 @entity3257
UNASSIGNED: The United States is experiencing an epidemic of @entity1445 ( @entity4968 ) @entity204 . Since 2000, the rate of @entity204 from drug @entity1445 has increased 137%, including a 200% increase in the rate of @entity1445 @entity204 involving opioids ( @entity158 relievers and @entity4521 ). CDC analyzed recent multiple cause-of- @entity204 mortality data to examine current trends and characteristics of @entity1445 , including the types of opioids associated with @entity1445 . During 2014, a total of 47,055 @entity1445 occurred in the United States, representing a 1-year increase of 6.5%, from 13.8 per 100,000 @entity1 in 2013 to 14.7 per 100,000 @entity1 in 2014. The rate of @entity1445 increased significantly for both sexes, @entity1 aged 25-44 years and >= 55 years, @entity3257 , and in the Northeastern, Midwestern, and Southern regions of the United States. Rates of opioid @entity1445 @entity204 also increased significantly, from 7.9 per 100,000 in 2013 to 9.0 per 100,000 in 2014, a 14% increase. Historically, CDC has programmatically characterized all @entity158 reliever @entity204 (natural and semisynthetic opioids, @entity284 , and other synthetic opioids) as "prescription" opioid @entity1445 (1). Between 2013 and 2014, the age-adjusted rate of @entity204 involving @entity284 remained unchanged; however, the age-adjusted rate of @entity204 involving natural and semisynthetic @entity158 relievers, @entity4521 , and synthetic opioids, other than @entity284 (e.g., @entity3575 ) increased 9%, 26%, and 80%, respectively. The sharp increase in @entity204 involving synthetic opioids, other than @entity284 , in 2014 coincided with law enforcement reports of increased availability of illicitly manufactured @entity3575 , a synthetic opioid; however, illicitly manufactured @entity3575 cannot be distinguished from prescription @entity3575 in @entity204 certificate data. These findings indicate that the opioid @entity1445 epidemic is worsening. There is a need for continued action to prevent @entity4784 , @entity734 , and @entity204 , improve treatment capacity for @entity4784 , and reduce the supply of illicit opioids, particularly @entity4521 and illicit @entity3575 .
