Prevalence and clinical significance of XXXX .

@entity1 @entity339 @entity3454 @entity1000 @entity10860 @entity74 @entity337 @entity299 @entity1146 @entity2333 @entity884
The prevalence and clinical significance of @entity10860 were determined prospectively in 2000 consecutive @entity1 undergoing routine clinical cross sectional echocardiography. Two hundred and twelve @entity1 were excluded because the aortic cusps were not adequately visualised. @entity10860 was defined as downward displacement of cuspal material below a line joining the points of attachment of the aortic valve leaflets. Twenty four cases of @entity10860 (1.2%) were identified. The @entity1 were aged 12-64 years and nine were @entity1 . All had underlying @entity299 and the commonest lesion (in 11 cases) was prolapse of the larger cusp in bicuspid valves. @entity10860 was seen in four @entity1 with @entity3454 (two with severe regurgitation), one of whom had marfanoid aortic root dilatation. The remaining examples of aortic prolapse were seen in @entity1 with @entity74 including one with @entity1146 , two with @entity2333 (one with dissection and one with @entity1000 ), and one case of severe @entity339 . Valves destroyed by @entity884 were seen in two cases. @entity10860 may be detected in various @entity299 and does not imply the presence of @entity337 , but when bicuspid aortic valves are present it may well be important in producing such regurgitation. Although @entity10860 may be associated with severe forms of @entity3454 , these @entity1 rarely have @entity337 .
