[ XXXX LEVELS AS A RISK FACTOR DURING PREGNANCY; BIOLOGICAL MODELING; SYSTEMATIC REVIEW].

@entity1 @entity172 @entity101 @entity6 @entity66 @entity1674 @entity2690 @entity412 @entity1468 @entity65
INTRODUCTION: introduction: Some of the diseases that can appear in pregnancy (gestational @entity6 , @entity101 and @entity1468 ) are being associated with an increased risk of heart throughout @entity66 . This should be present in future assessments of the health of @entity1 . One of the most important biomarkers in @entity65 is the @entity412 level, and that undergoes a significant change during pregnancy. OBJECTIVE: the objective of this review is to analyze the studies that have investigated @entity412 levels during pregnancy as a risk factor for @entity65 in the last weeks of pregnancy and childbirth. METHODS: a systematic search was made and 14 specific articles on the subject were selected following the PRISMA guidelines. RESULTS: in normal pregnancy decreased the level of lipids in the first weeks, followed by a gradual increase. Especially high from the 12th week of gestation. This increase in plasma levels of circulating lipids occurs linearly, reaching a peak a few days before delivery. This increase results because of the increased @entity172 levels and @entity2690 resistance. It has also been associated with prolactin levels. CONCLUSIONS: through this review, it has been able to demonstrate the relationship of elevated @entity1674 some pathologies or more frequent changes in risk pregnancies, in which a significantly higher elevation occurs compared to normal pregnancies. It is in this context that the biological modeling may be particularly important, facilitating the creation of models and percentile curves applicable to the population, and allow monitoring of changes in @entity1674 , which end up pointing situations passing be predictors of a potentially pathological situation. Thus, appropriate interventions would be carried rafter more briefly, and see so favored adequate primary prevention.
