The effect of anaesthetic management on @entity15901 ( XXXX ) levels after robotic surgical oncology.

@entity1 @entity8 @entity810 @entity1011 @entity15901
PURPOSE: The main objective of this study was to compare the effect of two anaesthetic techniques (general vs combined) on plasma levels of @entity15901 ( @entity15901 ) after robotic urogenital oncosurgery. The secondary objective was to correlate @entity15901 levels with the incidence of @entity810 ( @entity810 ). METHODS: This was a longitudinal prospective study. Forty @entity1 were included and randomized in 2 groups: group C (N=16 cases; combined general-epidural anesthesia) and group G (N=24 cases; control group with general anesthesia). Demographic data, Charlson Comorbidity Index, Apache II, SOFA and ASA scores were similar in both groups. Serum @entity1011 was determined preoperatively and every 24 hrs for 4 postoperative days to identify @entity810 according to RIFLE and AKIN criteria. Serum @entity15901 was determined at 6 and 12 hrs after induction of anesthesia. RESULTS: Serum creatinine increased at 24 hrs postoperatively in both groups as compared to baseline, but significant changes were registered only in the G group (pcontrol = 0.004). Serum @entity15901 increased significantly in both groups as compared with baseline levels (pcase=0.0034 vs pcontrol=0.0001). The incidence of @entity810 was 12.50% (95% CI 0.4-34) in the C group and 37.50% (95% CI 17-58) in the G group (p=0.0909), respectively. CONCLUSION: @entity8 and @entity810 occurred in robot-assisted laparoscopic urogenital oncosurgery under both general and combined anaesthesia. The incidence of @entity810 was lower in @entity1 undergoing combined anesthesia compared to general anaesthesia after robotic urogenital oncosurgery but the difference did not reach statistical significance. However, plasma levels of @entity15901 were significantly increased at 6 and 12 hrs in the general anaesthesia group as compared with combined anaesthesia. @entity15901 may be a better marker in detecting postoperative @entity810 . Further studies are needed.
