Antifungal agent utilization evaluation in hospitalized neutropenic XXXX @entity1 at a large teaching hospital.

@entity1 @entity2379 @entity2380 @entity5 @entity5074
To evaluate pattern of using of three antifungal drugs: @entity2380 , @entity2379 and @entity5074 , at the hematology-oncology and bone marrow transplant wards of one large teaching hospital. In a prospective cross-sectional study, we evaluated the appropriateness of using antifungal drugs in @entity1 , using Infectious Disease Society of America (IDSA) and National @entity5 Network (NCCN) guidelines. All the data were recorded daily by a pharmacist in a form designed by a clinical pharmacist and infectious diseases specialist, for antifungals usage, administration, and monitoring. During the study, 116 @entity1 were enrolled. Indications of prescribing @entity2379 , @entity2380 , and @entity5074 were appropriate according to guidelines in 83.4%, 80.6%, and 76.9% respectively. The duration of treatments were appropriate according to guidelines in 75%, 64.5%, and 71.1% respectively. The dose of @entity5074 was appropriate according to guidelines in 46.2% of @entity1 . None of the @entity1 received salt loading before administration of @entity2379 . The most considerable problems with the mentioned antifungals were about the indications and duration of treatment. In addition, prehydration for @entity2379 and dosage of @entity5074 were not completely compatible with the mentioned guidelines. A suitable combination of controlling the use of antifungals and educational programs could be essential for improving the general process of using antifungal drugs at our hospital.
