Radionuclide esophageal emptying and manometric studies in XXXX .

@entity1 @entity1318 @entity6 @entity16 @entity344 @entity1897 @entity1208 @entity4148 @entity1282 @entity989 @entity2412
Esophageal function was prospectively studied in 50 consecutive insulin-requiring @entity6 @entity1 . The @entity1 were stratified in three groups: A) 18 without @entity1897 ( @entity1897 ); B) 20 with @entity1897 but no @entity4148 ; C) 12 with @entity1897 and @entity4148 . Twelve @entity1 (four B, eight C) had gastrointestinal symptoms including six with @entity1282 . Radionuclide esophageal emptying was abnormal in 55, 70, and 83% of @entity1 in groups A, B, and C, respectively. Eleven of the 12 (92%) symptomatic and 23 of the 38 (60%) asymptomatic @entity6 @entity1 had abnormal emptying. Five of six @entity1 with @entity1282 had abnormal emptying. Esophageal manometry was also performed in 15 @entity1 . Twelve @entity1 had abnormal manometry. These included nutcracker esophagus in two, @entity1318 in one, and increased percentage of multipeaked and simultaneous contractions in nine. There were no significant correlations between radionuclide esophageal emptying, manometric changes and symptoms. @entity344 were more common in the presence of @entity4148 . Delayed esophageal emptying was more profound in the presence of @entity1897 , but abnormal esophageal emptying was present in @entity1 with @entity16 as commonly as @entity1 without. Furthermore, the presence of @entity6 , duration or control of diabetics, and fasting blood sugar did not influence the frequency of abnormal esophageal emptying. Our data indicate that @entity1208 is common in male diabetics even in the absence of clinical @entity1897 and @entity989 , suggesting that @entity6 can occur in the absence of significant @entity2412 . Commonly observed abnormal esophageal manometry in diabetics is not necessarily accompanied by significant functional disturbances or symptoms.
