XXXX of the anal sac glands in ranch mink.

@entity2741 @entity5 @entity189 @entity1800 @entity3
During a 14-year period, @entity189 of the anal sac apocrine glands was found in 52 pastel and 8 sapphire mink (Mustela vison) kept for studies on slow @entity1800 . The pastel mink varied in age from 72 to 135 months (mean age 108 months), the sapphire mink from 63 to 100 months (mean age 81 months). All but one pastel mink were females. The @entity5 varied in size from masses that caused bulges in the perineum to those that were found only after microscopic examination of the anal sac glands. Although the @entity5 grew mainly by expansion with little local infiltration, 41 of the 60 @entity5 had metastasized to the regional lymph nodes and sometimes also to more distant sites. The striking propensity of the @entity189 to @entity3 while still small, even microscopic, often resulted in massive secondary growths, notably in the iliac lymph nodes. @entity2741 did not accompany the @entity189 . Its varied microscopic appearance included solid, glandular, squamous cell, and spindle or round cell components. Combinations of them formed mixed or complex histologic patterns, no doubt largely attributable to neoplastic proliferation of myoepithelial cells and squamous metaplasia of the apocrine gland epithelium. Although its cause remains obscure, the @entity189 appeared to arise from small foci of hyperplastic apocrine glands, sometimes in relation to both anal sacs. The @entity5 is a common and distinctive expression of @entity5 in older ranch mink.
