Predictors of Poor Quality of Life 1 Year After XXXX .

@entity1 @entity308 @entity295 @entity1276 @entity510 @entity55 @entity73 @entity1188
BACKGROUND: Risk factors for poor quality of life (QOL) after @entity510 ( @entity510 ) remain poorly described. OBJECTIVE: To identify the frequency and predictors of poor QOL 1 year after @entity510 . METHODS: We studied 1-year QOL in a prospectively collected cohort of 1181 consecutively admitted @entity510 survivors between July 1996 and May 2013. @entity1 clinical, radiographic, surgical, and acute clinical course information was recorded. Reduced QOL (overall, physical, and psychosocial) at 1 year was assessed with the Sickness Impact Profile and defined as 2 SD below population-based normative Sickness Impact Profile values. Logistic regression leveraging multiple imputation to handle missing data was used to evaluate reduced QOL. RESULTS: Poor overall QOL was observed in 35% of @entity1 . Multivariable analysis revealed that nonwhite ethnicity, high school education or less, history of @entity308 , poor clinical grade (Hunt-Hess Grade >= 3), and delayed @entity1188 were predictors of poor overall and psychosocial QOL. Poor physical QOL was additionally associated with older age, @entity1276 , @entity55 , and @entity295 . At 1 year, @entity1 with poor QOL had increased difficulty concentrating, @entity73 , @entity308 , and reduced activities of daily living. More than 91% of @entity1 with poor QOL failed to fully return to work. These @entity1 frequently received physical rehabilitation, but few received cognitive rehabilitation or emotional-behavioral support. CONCLUSION: Reduced QOL affects as many as one-third of @entity510 survivors 1 year after @entity510 . Delayed @entity1188 is the most important in-hospital modifiable factor that affects QOL. Increased attention to cognitive and emotional difficulties after hospital discharge may help @entity1 achieve greater QOL.
