Leaflet-Chordal Relations in @entity1 with XXXX .

@entity3656 @entity1 @entity339
BACKGROUND: The strategy for mitral valve (MV) repair has recently focused on the restoration of the submitral apparatus. However, the relationship between geometric changes of the submitral apparatus and the mitral leaflets has not been systematically investigated. The aim of this study was to determine the relationships among @entity3656 ( @entity3656 ) and LV size and leaflet surface area (LSA) in normal subjects, @entity1 with primary (degenerative) @entity339 (PMR), and @entity1 with functional (secondary) @entity339 (FMR). METHODS: A total of 72 @entity1 who underwent three-dimensional transesophageal echocardiography, including: 27 with PMR with isolated P2 flail leaflet, 25 with FMR with greater than mild @entity339 , and 20 with normal mitral valves. LSA was quantified at midsystole from full-volume midesophageal views. @entity3656 was calculated by averaging the lengths of eight primary chords from transgastric full-volume data sets using multiplanar reconstruction. RESULTS: Both @entity3656 and LSA in the PMR group were significantly longer compared with the FMR and normal control groups. No difference in @entity3656 was noted between @entity1 with FMR and normal subjects. In all three groups, @entity3656 and LSA did not correlate with LV systolic or diastolic dimensions. Although @entity3656 did not correlate with LSA in the FMR group, a moderate correlation (R  =  0.62) was observed in the PMR group. CONCLUSIONS: In @entity1 with FMR with greater than mild @entity339 , the chords retain normal length, despite LSA and LV enlargement. In @entity1 with PMR with flail P2 scallops, @entity3656 elongation of primary chords is associated with larger LSA but not with LV dimensions. This information may have implications for clinical strategies for mitral valve repair surgery, including the submitral approach and percutaneous procedures.
