Job strain and the prevalence and outcome of XXXX .

@entity1 @entity583 @entity301 @entity797 @entity951 @entity299 @entity453 @entity204
BACKGROUND: It has been hypothesized that jobs that have both high psychological demands and low decision latitude ("job strain") can lead to @entity301 . The objective of this study was to test whether job strain was correlated with the presence of @entity301 at angiography or with long-term outcome in @entity1 with @entity301 . METHODS AND RESULTS: Employed @entity1 under the age of 65 years undergoing diagnostic coronary angiography completed a self-administered questionnaire about their job duties and work environment. Job strain was measured by the method of Karasek. @entity1 were separated into three groups, based on extent of @entity301 : significant disease (> or = 75% stenosis), insignificant disease (> 0% but < 75% stenosis), and normal coronary arteries. Statistical analyses were performed using logistic regression and the @entity797 proportional hazards model. The 1489 @entity1 enrolled had a median age of 52 years; 76% were male and 88% were white. By design, all @entity1 were employed, 60% in white-collar jobs and only 16% in jobs requiring heavy labor. Traditional cardiac risk factors were most prevalent in the 922 @entity1 with significant @entity453 , at intermediate levels in the 204 @entity1 with insignificant disease, and least prevalent in the 363 @entity1 with normal coronary arteries (all P < .01). Job strain was actually more common in @entity1 with normal coronary arteries (35%) than in @entity1 with insignificant (26%) or significant disease (25%, P < .002). In a multivariate analysis, job strain was not significantly correlated with the presence of @entity301 . Job strain was not correlated with @entity951 frequency at the time of angiography. Job strain was not a predictor of @entity299 ( @entity204 or nonfatal @entity583 ) during follow-up. CONCLUSIONS: Job strain was not correlated with the prevalence or severity of @entity453 in a cohort of @entity1 undergoing coronary angiography. The outcome of @entity1 with angiographically defined @entity301 was not affected by the level of job strain as measured by the method of Karasek.
