Platelet activation after endovascular repair of XXXX .

@entity1 @entity439 @entity8729 @entity2635 @entity1028 @entity4210 @entity1851
AIM: To investigate the effect of @entity439 repair (EVAR) on platelet (PLT) function and reveal possible associated factors. METHODS: Fifty consecutive @entity1 were included. PLT count and activation ( @entity8729 - @entity4210 ), white blood cell (WBC) count, and high sensitivity @entity1851 (hs-CRP) were measured preoperatively, at the first and third postoperative day. RESULTS: EVAR elicited a significant reduction in PLT count from baseline to first day after EVAR (p   <   0.001), while no significant difference was noted between the first and third day. Furthermore, @entity8729 expression was markedly elevated at the first day after EVAR (median % positive PLTs from 13.7 at baseline to 22.1, p   =   0.05), but returned to baseline levels by the third day. Maximum @entity1028 diameter was the only factor that significantly affected the @entity8729 values (p   =   0.005). Postoperative @entity4210 values were significantly correlated with total @entity439 volume (p   =   0.05) and were higher in endografts made from @entity2635 (p   =   0.01). There were no correlation between PLT activation and hs-CRP, WBC, maximum temperature, and 30-day morbidity. CONCLUSION: EVAR has elucidated a significant reduction in PLT count and increase in PLT activation at the immediate postoperative period. The type of the endograft material and the @entity439 maximum diameter and volume appear to play an important role in PLT activation.
