Accuracy of diagnostic imaging as determined by delayed operative intervention for advanced XXXX .

@entity1 @entity66 @entity5 @entity2996 @entity521 @entity2246
Current treatment of newly diagnosed widespread @entity521 may include chemotherapy, delayed surgical resection, marrow ablative chemoradiotherapy, and bone marrow transplantation. @entity2996 ( @entity2996 ) with computerized tomography (CT) or magnetic resonance imaging (MRI) has been used to determine response to therapy and timing of delayed resection. We assessed the accuracy of @entity2996 in 25 @entity1 (26 total cases) treated over 21 months. @entity5 size and location were estimated prior to surgical resection by @entity2996 , and the sensitivity and specificity of these studies were determined from operative findings. @entity2996 consisted of CT (15), MRI (8), and MRI and CT (3). Discordance between @entity2996 and operative findings was found in ten @entity1 (38%). This included three @entity2246 (12%), including two false-positives and one false-negative. Seven errors of specificity were noted; they included a positive scan with no viable @entity5 identified (3), much more @entity66 (3), or less @entity66 (1). Viable @entity5 was identified in 18 cases, and in 11 @entity1 , complete resection of macroscopic @entity5 at the primary site was carried out. Ten of 13 @entity1 operated on within 5 months of beginning chemotherapy were rendered grossly free of @entity521 at the primary site after surgery. Eight of 12 @entity1 operated on 6 months or longer after starting chemotherapy were rendered grossly free of @entity5 at the primary site. Bone marrow transplantation was performed in 21 @entity1 , ten of whom are alive with a median follow up of 20 months. Survival was similar for @entity1 who underwent surgical resection at less than or equal to 5 v greater than 6 months after starting chemotherapy.(ABSTRACT TRUNCATED AT 250 WORDS)
