Efficacy of @entity3400 / XXXX in the treatment of experimental @entity1320 .

@entity1 @entity801 @entity254 @entity7120 @entity3400 @entity35 @entity1320 @entity3402
A reproducible animal model of @entity1320 was devised to simulate @entity1320 in @entity1 and emulate clinical trials. Preoperatively, @entity35 were fed lean ground beef for two weeks to change their intestinal flora to one similar to that of @entity1 . A 1 cm segment of ileum was isolated on its vascular pedicle. The intestine was then divided at each end of the segment and continuity re-established by end-to-end @entity254 . The isolated segment was returned to the abdominal cavity. This model was used to compare @entity3400 / @entity7120 with imipenem and with @entity3402 plus @entity801 in treating the resulting infections. Eighty per cent of untreated animals died within three days. Treated animals had significantly reduced mortality and increased cure rates. One treated animal (in the @entity3402 - @entity801 group) died. These results support the findings of the efficacy of @entity3400 / @entity7120 in treating @entity1320 in @entity1 clinical trials.
