Long pulsed 1064 nm Nd:YAG laser treatment for XXXX : evaluation of new parameters.

@entity1162 @entity158 @entity272
INTRODUCTION: Among non-ablative devices for @entity272 , @entity1162 ( @entity1162 ) has considerable effectiveness. It can penetrate to deep dermis due to its longer wavelength. This study assesses the efficacy and safety of @entity1162 applying new parameters for skin rejuvenation in Korean subjects. METHODS: A prospective randomized split-faced study was done (n = 20). Half of the face was treated with three passes of @entity1162 at a spot size of 12 mm, 20-24 J/cm(2) fluence, 12 ms width, and frequency of 2 Hz, for three sessions, every four weeks. Outcomes were measured by wrinkle evaluation of blinded investigators, subjects' self-assessment, objective measurements of elasticity, and skin biopsy. RESULTS: Four weeks after the final treatment sessions, the average wrinkle grades of the treated side were reduced by 45.1%. Skin elasticity was significantly increased. The increment of collagen and elastic fiber in papillary dermis was confirmed histologically. No adverse reaction was reported. @entity158 on the treated side was mild without needing anesthesia. DISCUSSION: The authors studied new parameters for @entity1162 for improvement of wrinkles and @entity272 with fewer treatment sessions without serious complications. Histologic findings corresponded to clinical improvement. CONCLUSION: New parameters of @entity1162 can achieve wrinkle improvement with few side effects.
