Multiple @entity1943 - and XXXX -containing carcinoids of the duodenum: report of a case treated by pancreas-sparing duodenectomy.

@entity1 @entity1127 @entity75 @entity5 @entity16857 @entity8243 @entity4303 @entity1943
A 59-year-old Japanese @entity1 was incidentally discovered to have @entity1127 in the duodenum by endoscopy during a health checkup. Laboratory studies showed an elevated level of serum @entity1943 . The mutation of the @entity16857 gene was not observed. An endoscopic examination revealed @entity75 in the bulbus and in the second portion of the duodenum. An upper gastrointestinal series also showed the @entity75 in the bulbus, and in the descending and horizontal portions of the duodenum. The biopsy specimen showed small monotonous cells with round nuclei compatible with a @entity5 . The @entity5 cells were positive for @entity1943 and @entity8243 . Based on the clinical diagnosis of @entity4303 of the duodenum, a pancreas-sparing duodenectomy was performed. Macroscopic findings showed about 30 polypoid lesions throughout the duodenum. The biggest one was not over 10 mm in size. A histological examination revealed well-demarcated @entity5 located in the submucosal layer. Immunohistochemically, the @entity5 were diffusely positive for @entity1943 and were scatteringly positive for @entity8243 . The @entity1 's postoperative course of treatment was uneventful and his postoperative serum @entity1943 went down to normal range. The pancreas-sparing duodenectomy is a safe and effective treatment in @entity1 with @entity4303 of the duodenum, that are smaller than 1 cm in size.
