Exocrine XXXX in @entity295 .

@entity1 @entity295 @entity326 @entity1457 @entity3124 @entity660 @entity3157 @entity1063
BACKGROUND: @entity295 in @entity3124 is associated with the progressive failure of multiple organs. This study aims to establish a correlation between the severity of @entity295 and exocrine @entity660 . MATERIALS AND METHODS: In a prospective cohort study pancreatic exocrine function was tested by means of a secretin-cholecystokinin test in 21 critically ill, mechanically ventilated @entity1 with @entity295 according to criteria of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee (ACCP/SCCM): 11 @entity1 with @entity1457 and 10 @entity1 without @entity1457 . Data were compared with seven healthy controls. RESULTS: The volume of duodenal fluid was not statistically different in the three groups. @entity295 @entity1 without @entity1457 had significantly reduced content of amylase and chymotrypsin in duodenal juice compared with healthy controls (P < 0.01). Secretion of amylase, chymotrypsin, trypsin (P < 0.01 each) and @entity3157 in duodenal fluid (P < 0.05) was impaired in the @entity326 @entity1 when compared with the healthy controls. The content of trypsin was different between @entity295 @entity1 and @entity326 @entity1 (P < 0.05). Spearman correlation analysis was significant between the amylase secretion and the APACHE III and SOFA scores (P < 0.01). The SOFA score was also related to secretion of trypsin (P < 0.05). In @entity1 on pressor therapy, use of @entity1063 was associated with a significant decrease in @entity3157 secretion (P < 0.05). CONCLUSIONS: @entity295 is associated with secretory @entity660 that is worse in @entity326 than in @entity295 without @entity1457 . Impaired exocrine function was significantly correlated to the APACHE III and SOFA scores.
