Use of atosiban in a twin pregnancy with extremely preterm XXXX in the membrane of one twin: a case report and literature review.

@entity1 @entity3556 @entity3152 @entity9803 @entity2400 @entity9994 @entity397 @entity358
OBJECTIVE: Pregnancies with extremely preterm @entity397 of membranes (EPPROM), especially before 20 weeks of gestation, are usually considered to be a termination of pregnancy. By improvement of obstetric and neonatal care, we can prolong the pregnancy across the threshold of survival by aggressive tocolysis. CASE REPORT: Using intrauterine insemination, a 32-year-old @entity1 became pregnant with twins (first pregnancy). @entity9803 occured since 9 weeks of gestation and EPPROM of the upper twin was noted at 18 weeks. Massive @entity3556 and vigorous uterine contractions occurred at 22 weeks. Poor control of @entity3152 occurred using @entity9994 and @entity2400 . Atosiban was applied to calm uterine activities. After discontinuation of atosiban at 30 weeks, the uterine contractions became severe again and an emergency cesarean section was performed to deliver two live, premature babies weighing 1,518 g and 830 g, respectively. Twin A was healthy, weighing 2,030 g at 35 days after birth and subsequently discharged. The smaller twin B was dependent on continuous positive airway pressure and died of @entity358 120 days after birth. CONCLUSION: Comparing to other tocolytic agents, Atosiban has few side effects and assisted in prolonging a pregnancy involving twins that experienced EPPROM.
