The Epidemiology and Health Care Burden of XXXX : A Population-Based Study.

@entity1 @entity1162 @entity2633 @entity924
BACKGROUND: @entity924 ( @entity2633 ) is a common condition both in primary care and specialty clinics. PURPOSE: To evaluate the natural history (ie, incidence, recurrence, and progression to surgery) of @entity924 in a large population. STUDY DESIGN: Descriptive epidemiology study. METHODS: The study population comprised a population-based incidence cohort of @entity1 with new-onset @entity924 between January 1, 2000, and December 31, 2012. The medical records of a 10% random sample (n = 576) were reviewed to ascertain information on @entity1 and disease characteristics, treatment modalities, recurrence, and progression to surgery. Age- and sex-specific incidence rates were calculated and adjusted to the 2010 US population. RESULTS: The age- and sex-adjusted annual incidence of @entity924 decreased significantly over time from 4.5 per 1000 @entity1 in 2000 to 2.4 per 1000 in 2012 (P < .001). The recurrence rate within 2 years was 8.5% and remained constant over time. The proportion of surgically treated cases within 2 years of diagnosis tripled over time, from 1.1% during the 2000-2002 time period to 3.2% after 2009 (P < .00001). About 1 in 10 @entity1 with persistent symptoms at 6 months required surgery. CONCLUSION: The decrease in incidence of @entity924 may represent changes in diagnosis patterns or a true decrease in disease incidence. Natural history data can be used to help guide @entity1 and providers in determining the most appropriate course at a given time in the disease process. The study data suggest that @entity1 without resolution after 6 months of onset may have a @entity1162 and may need surgical intervention.
