Early Clinical Results of a Novel Ab Interno Gel Stent for the Surgical Treatment of XXXX .

@entity1 @entity227 @entity1538 @entity1138 @entity726
PURPOSE: To evaluate the intraocular pressure (IOP) lowering effect of the XEN140 microfistula gel stent implant for the surgical treatment of @entity1538 . @entity1 AND METHODS: Forty-nine eyes of 49 @entity1 with an IOP>18 mm Hg and  <=35 mm Hg were studied in a prospective nonrandomized multicenter cohort trial of the surgical implantation of the XEN140 implant in @entity1 with @entity1538 . Complete success was defined as a postoperative IOP <=18 mm Hg with >= 20% reduction in IOP at 12 months without any @entity726 medications. Failure was defined as @entity227 or worse, need for additional @entity726 surgery, or <20% reduction of IOP from baseline. RESULTS: The average age was 64.3 (28.1 to 86.9) years old. Twenty-one eyes had prior failed trabeculectomy with @entity1138 surgery. IOP at 12 months decreased from a mean of 23.1 (  4.1) mm Hg to 14.7 (  3.7) mm Hg for a 36.4% reduction in IOP from baseline. The number of @entity1 at 12 months who achieved an IOP <=18 mm Hg and >= 20% reduction in IOP was 40 (89%). The number of @entity1 who achieved an IOP <=18 mm Hg and >= 20% reduction in IOP without antiglaucoma medications was 18 (40%). CONCLUSIONS: The XEN140 gel stent lowers IOP with few complications when implanted for the surgical treatment of @entity1538 .
