Disparities in prevalence, location, and shape characteristics of XXXX between South Korean and U.S. @entity1 .

@entity1 @entity19329 @entity5 @entity14 @entity652 @entity694
BACKGROUND: @entity694 screening is being introduced in many countries, but standard Western screening approaches may not be appropriate for Asian societies if differences in @entity694 epidemiology exist. Comparative analysis of @entity14 patterns in South Korean and Western subjects has implications for appropriate screening approaches in non-Western societies. METHODS: The results of concurrent screening colonoscopies performed in average-risk @entity1 50 to 69 years old in 2 teaching hospitals, Kyung Hee University Hospital (Seoul, South Korea) and Virginia Mason Medical Center (Seattle, @entity19329 ), were compared with respect to prevalence, histologic features, anatomic distribution, and shape characteristics of @entity14 . RESULTS: The U.S. (n  = 3460) and South Korean (n  = 2193) cohorts were similar with regard to the prevalence of @entity652 (28.5% vs 29.8%, respectively, P  = .312) and advanced @entity5 (6.4% vs 5.4%, respectively, P  =  .102), but the proportion of proximal @entity652 was greater in the U.S. cohort (62.8% vs 45.9%, P  <  .001). The prevalence of @entity652 and advanced @entity5 was similar in male @entity1 , but there was a greater prevalence of @entity5 (23.5% vs 18.8%, P  = .006) and advanced @entity5 (5.1% vs 2.7%, P  < .001) in U.S. @entity1 than South Korean @entity1 . When large (>= 10  mm) @entity652 were considered, proximal location and nonpolypoid (flat) shape were more common in the U.S. cohort (79.4% vs 37.1%, P  = .003 and 43.5% vs 12.3%, P  < .001, respectively). The overall prevalence of large flat @entity652 in the U.S. cohort was 5 times that of the South Korean cohort (2.6% vs 0.5%, P  < .001). Adjustment for sex ratio discrepancies (48.3% @entity1 in the U.S. cohort vs 60.8% in the South Korean cohort, P  < .001) did not result in any significant changes in the conclusions. CONCLUSION: Compared with Westerners, South Koreans have a more distal distribution of @entity652 and advanced @entity5 and lower prevalence of large flat @entity652 . South Korean @entity1 have a lower prevalence of @entity14 than Western @entity1 . Such disparities suggest that Western screening strategies cannot be  directly adopted by other countries, but need to be customized by society.
