Association of XXXX blood types with the risk of in-stent restenosis.

@entity1 @entity412 @entity6910
OBJECTIVES: To investigate the prevalence of in-stent restenosis (ISR) in @entity1 with various @entity6910 blood types. METHODS: Clinical information from 150 @entity1 with a confirmed diagnosis of ISR and 150 @entity1 with a diagnosis of patent coronary stents in the secondary angiography was collected. Comprehensive demographic and laboratory data, including @entity6910 and Rhesus blood groups, as well as comorbid conditions and vessel and stent characteristics, were recorded for each @entity1 . The association of @entity6910 blood groups with the risk of ISR before and after controlling for coronary risk factors was determined. Categorical data were analyzed with the Chi-square test and numerical values were analyzed with t-tests. Binary logistic regression models were constructed to compare type A and non-A for the frequency of risk factors. RESULTS: A total of 392 stents were implanted in 300 @entity1 . Two hundred and fourteen stents (54.6%) were patent and 178 stents (45.4%) were stenosed. Blood group A was significantly more common in the ISR group (43.3% vs. 28.7%, p=0.03). However, the frequencies of other blood types, as well as Rh antigen, were similar between the two groups. @entity412 and low-density lipoproteins were the only significantly different variables (221    198 mg/dL vs. 138    76 mg/dL, p<0.001 and 108    36 mg/dL vs. 96    73 mg/dL, p=0.04, in type-A vs. non-A, respectively). After matching for coronary risk factors, there was no difference between A blood type @entity1 and their controls. CONCLUSION: ISR is significantly more prevalent in individuals with the type A blood group. However, this higher association is most likely due to higher atherogenic conditions in @entity1 within this population.
