Prognostic evaluation of @entity3558 -5AC expression in XXXX , mass-forming type, following hepatectomy.

@entity1 @entity146 @entity5 @entity5091 @entity5089 @entity1419 @entity3558 @entity3 @entity21826
AIM: This study aimed to investigate the clinicopathological predictors of survival in @entity1 with @entity1419 , mass-forming type (ICC-MF), following curative intent hepatectomy. METHODS: Clinical characteristics and outcomes were analyzed in a series of 42 @entity1 who underwent curative hepatectomy for ICC-MF between February 1987 and December 2012. The relationship between immunohistochemical expression profiles of @entity3558 ( @entity3558 ) core proteins ( @entity5091 , @entity5089 , and @entity21826 ) and surgical outcomes was examined. RESULTS: The overall median follow-up period was 2.6 years (0.2-17.9). Bile duct reconstruction (p  =  0.017), lymph node @entity3 (p  =  0.049), maximal mass diameter >= 5.0  cm (p  =  0.002), and @entity5089 expression (p  =  0.003) were identified as significant adverse predictors of overall survival by univariate analysis. Bile duct reconstruction (p  =  0.048), maximal mass diameter  >= 5.0  cm (p  =  0.002), and @entity5089 expression (p  =  0.005) were found to be independent predictors of poor prognosis by multivariate analysis. Maximal mass diameter >= 5.0  cm (p  =  0.011) was found to be an independent predictor for the @entity5 recurrence. There was a strong correlation between @entity5089 expression and lymph node @entity3 (p  =  0.021). @entity21826 expression was more frequent in @entity1 with concurrent @entity5089 expression (p  =  0.019). CONCLUSIONS: @entity5089 expression was significantly related to long-term prognosis and @entity146 development, and may be a useful prognostic marker.
