Volumetric Modulated Arc Therapy of the Pelvic Lymph Nodes to the Aortic Bifurcation in Higher Risk Prostate Cancer: Early XXXX Outcomes.

@entity1 @entity137 @entity263 @entity5 @entity344 @entity1486
Background. Treatment of pelvic lymph nodes (PLNs) in higher risk @entity263 is controversial. The primary focus of the study was to evaluate the early @entity137 profile for this cohort of @entity1 treated with Volumetric Modulated Arc Therapy (VMAT). Methods. @entity1 , @entity5 , and treatment characteristics of those who received VMAT from May 2010 to December 2012 were analysed. A simplified contouring process of the PLNs to the aortic bifurcation was developed based on consensus guidelines. @entity344 were documented according to the Radiation Therapy Oncology Group (RTOG) Version 2 Guidelines. Successive @entity1486 (PSA) values after treatment were measured on average 3 months apart. Results. 113 @entity1 were treated between May 2010 to December 2012 with a median follow-up of 14 months. No @entity1 experienced acute grade 3 or 4   GU and @entity344 . Only 1 @entity1 experienced a late grade 3   GU complication. No late grade 4   GU or GI events have yet occurred. Conclusions. This study reviews the first Australian experience of VMAT in the treatment of pelvic lymph nodes in @entity263 , specifically to the level of the aortic bifurcation. It demonstrates a favorable acute @entity137 profile whilst treating large PLN volumes with optimal dose coverage.
