Subgingival microflora and treatment in XXXX associated with @entity4752 .

@entity1 @entity2172 @entity527 @entity11281 @entity868 @entity235 @entity604 @entity6223 @entity5389 @entity4752 @entity3288 @entity10188 @entity1729 @entity2521 @entity3841 @entity2523
@entity6223 affects both primary and permanent dentition. The purpose of this study was to examine the composition of subgingival microflora of the permanent dentition in an 11-year-old Caucasian female, who had premature exfoliation of her deciduous teeth on her 5th year of age, and the response of this condition to the antibiotic therapy and supportive periodontal care. Gingival tissues were highly inflamed and @entity604 was detected radiographically. The @entity1 had experienced frequent @entity1729 , @entity5389 and recurrent @entity2172 . Her mother had history of early onset @entity2521 associated with @entity4752 . Blood chemistry tests and immunological examinations were also performed. @entity527 samples were collected from the proximal sites of permanent molars, incisors, @entity235 and maxillary premolars. 27 different microbial species were isolated from the subgingival microflora. Among the predominant species were @entity2523 (17.6%-7.3%), @entity3288 (12.4%-4.7%), @entity11281 sputigena (14.4%-10.4%), @entity11281 (13.2%-6.9%) and @entity3841 (9.3%-5.5%). Periodontal treatment consisted of scaling, root planing in conjunction with antibiotic administration of @entity10188 312.5 mg and @entity868 200 mg, each t.i.d. for 10 days. 3 weeks after the antibiotic therapy, bacterial samples were collected from the same sites. All the periodontal pathogens were recovered in lower levels and A.actinomycetemcomitans was almost eliminated in the 3-week period. The evaluation of clinical indices at 3, 6 and 12 months showed that periodontal treatment in conjunction with antibiotics was effective and rapidly followed by marked clinical improvement. The microbiological monitoring at 3, 6 and 12 months after antibiotic treatment and each time prior to supportive periodontal care, revealed that the periodontal pathogens fluctuated in low levels even 12 months after treatment and could be maintained at low level by supportive periodontal care at 3-month intervals.
