[Preoperative management of uterine XXXX using pituitary gonadotropin-releasing hormone analogues].

@entity20866 @entity1 @entity21278 @entity548 @entity5 @entity7296 @entity1868
Uterine @entity20866 shows a frequency from 25 to 30% in reproductive age @entity1 . Traditional treatment is hysterectomy or myomectomy independently from fertility wishes of the @entity1 . Its growth has been associated to estrogenic activity. Because of this, several substances have been used to diminish @entity5 size, pre-operatively. The use of analogues of liberating hormone of hypophysiary gonadotropins (GnRH), given to favor surgical technique, to diminish @entity548 and to avoid blood transfusions. Clinical efficiency of the use of @entity21278 in @entity1 with uterine leyomiomatosis, pre-operatively during three months, was studied in this paper. The study was prospective, comparative, blind and with longitudinal measurements. Twenty eight @entity1 were included. Group I (n = 13) and Group II (n = 15) control without treatment. Observation units included FSH, LH, E2, @entity7296 , HCT, USG basal, 30, 60, 90 days. Results showed a diminution of more than 80% of the initial uterine volume, and of 30% of the @entity1868 independently measured. Side effects, tolerance and efficacy of the used compound, are mentioned.
