Clinico- pathological profile and course of XXXX in a tertiary care teaching hospital in western U.P. with special reference to @entity2 .

@entity1 @entity0 @entity706 @entity5 @entity2 @entity3483
BACKGROUND: @entity3483 is a major clinical problem associated with primary and metastatic @entity5 . Pleural effusions from an unknown primary are responsible for 7-15% of all @entity3483 . Presence of @entity3483 puts the @entity1 in advanced stage and renders the prognosis as poor. AIM: In this study we intend to find out the incidence of @entity3483 , its aetiology and clinical course in @entity1 attending a tertiary care teaching hospital. RESULTS: A total of 308 @entity1 were included in this study. A majority of the @entity1 were in age group 50- 70 years (median age = 58.8 years; range 32- 85 yrs). Male to female ratio was 2.5:1. The major primary @entity5 were @entity2 (135), @entity706 (40), @entity0 (36), female genital tract (30) gastrointestinal (21), and others (8). In 38 cases primary remained unknown. The yields of pleural fluid cytology, blind pleural biopsy, CT/USG guided pleural biopsy and thoracoscopy were 60%, 49%, 76% and 91% respectively. Chemical pleurodesis yielded complete response in 80%, incomplete response in another 13% @entity1 . Only 136 (44%) cases could be followed up for minimum of 6 months. A majority of them (95, 69.85%) died. CONCLUSION: We conclude that @entity3483 is a commonly misdiagnosed medical entity. @entity2 is the commonest cause. Despite all efforts, in about 15% of the cases, primary remains undiagnosed. Thoracoscopy/pleuroscopy is a cost effective measure for diagnosis. Chemical pleurodesis provides expected results but mortality remains high.
