@entity460 channel blockers for @entity3326 induced XXXX .

@entity1 @entity3326 @entity1032 @entity353 @entity1855 @entity910 @entity3931 @entity914 @entity3988 @entity161 @entity460 @entity594 @entity717
BACKGROUND: @entity910 is a disfiguring @entity717 of the orofacial region often caused by antipsychotic drugs. A wide range of strategies has been used to help manage @entity910 and, for @entity1 who are unable to have their antipsychotic medication stopped or substantially changed, the @entity460 -channel blocking group of drugs ( @entity3988 , @entity594 , @entity3931 , @entity1855 ) has been suggested as a useful adjunctive treatment. OBJECTIVES: To determine the effects of @entity460 -channel blocker drugs ( @entity3988 , @entity594 , @entity3931 , @entity1855 ) for treatment of @entity3326 induced @entity910 in @entity1 with @entity161 , @entity914 or other chronic mental illnesses. SEARCH STRATEGY: We updated previous searches of the Cochrane @entity161 Group Register (1982-2000), Cochrane Library (Issue 4, 2000), Cochrane @entity161 Group's register of trials (November 2000), EMBASE (1980-2000), LILACS (1982-2000), MEDLINE (1966-2000), PsycLIT (1974-2000), and SCISEARCH by searching the Cochrane @entity161 Group Register (September 2003). We searched references of all identified studies for further trial citations and contacted authors of trials. SELECTION CRITERIA: Randomised clinical trials comparing @entity460 -channel blockers to placebo or no intervention for @entity1 with both @entity910 and @entity161 or serious @entity1032 . DATA COLLECTION AND ANALYSIS: Data were to have been independently extracted and analysed on an intention-to-treat basis. The relative risk (RR) and 95% confidence intervals (CI) of homogeneous dichotomous data were to have been calculated using a random effects model, and, where possible, the number needed to treat calculated. @entity353 ( @entity353 ) were to have been calculated for continuous data. MAIN RESULTS: No trials were included. We excluded fourteen studies; eight were not randomised, one did not use @entity460 channel blockers and five small, randomised, studies reported no usable data. REVIEWER'S CONCLUSIONS: The effects of @entity460 -channel blockers for antipsychotic induced @entity910 are unknown. Their use is experimental and should only be given in the context of well designed randomised studies.
