@entity157 formation in ddY XXXX with chronic schistosomiasis japonica.

@entity1 @entity308 @entity19 @entity5 @entity2043 @entity281 @entity2040 @entity157 @entity2042
Three hundred and ninety-five four-week-old SPF female ddY @entity19 were each exposed to 5 or 6 cercariae of @entity2042 (Japanese strain) on their shaved abdomens and were maintained in a conditioned clean environment and fed on sterilized food and water. Fecal examinations at 8 to 10 weeks postinfection (PI) revealed 169 @entity19 to be infected. More than half of them died within 30 weeks PI and 70 @entity19 that survived to the 50th week PI were sacrificed. At autopsy, we could find no schistosome eggs in the liver or intestinal wall of 9 @entity19 , and they were excluded. Out of 61 @entity19 which showed @entity2043 eggs in their livers, 48 had single or multiple @entity157 , while no @entity5 was observed in the livers of the 60 control @entity19 . The @entity5 were yellowish-white in color with distinct boundaries and the centers of the @entity5 were @entity308 in some cases. The size of the @entity5 varied from 1 to 20 mm in diameter. Most of the @entity5 retained the normal trabecular pattern, but in some cases the trabeculae were thickened, having wide vascular spaces. The @entity5 cells were PAS-negative and showed varieties of pleomorphism. The sizes of cells and nuclei varied greatly. These findings suggested some causal relationship between @entity2043 @entity281 and the @entity157 formation in the host's liver. In the chronic course of @entity2040 japonica in the endemic areas, @entity2043 @entity281 probably plays a role in @entity157 formation of @entity1 .
