Immunoexpression of interleukin 17 in XXXX .

@entity1 @entity32 @entity2520 @entity738 @entity4155 @entity45
INTRODUCTION: Interleukin (IL)-17 expression has been detected in @entity2520 , but its role in the disease process remains unclear. The present study compared the expression of @entity4155 in @entity45 and @entity738 and evaluated the association of this cytokine with clinical and radiographic findings. METHODS: @entity2520 (18 cysts and 20 @entity738 ) were obtained from 38 @entity1 subjected to periradicular surgery. Some clinical, radiographic, and cone-beam computed tomographic features were recorded. Silanized slides containing paraffin sections were used for the immunohistochemical reactions using anti- @entity4155 antibody. Image analysis was performed using an optical microscope, and each sample was divided into 5 high-power fields, which were evaluated for the expression of @entity4155 in the epithelium and connective tissues. Results were evaluated for correlations with the lesion size and the occurrence of symptoms and sinus tract. RESULTS: Expression of @entity4155 was significantly higher in cysts than in @entity738 (P = .02). Among the @entity45 , a thin epithelium showed significantly increased labeling for @entity4155 when compared with a hyperplastic epithelium (P = .003). @entity4155 expression was usually associated with focal accumulations of polymorphonuclear leukocytes. No association of @entity4155 expression with symptoms, sinus tract, or lesion size was observed (P > .05). CONCLUSIONS: The present study reinforces the notion that @entity4155 may take part in the pathogenesis of @entity2520 . A role in the exacerbation of @entity32 and cyst formation is suspected. Further studies are required to shed light on the specific functions of @entity4155 in periradicular inflammatory processes.
