The prevalence of @entity729 in XXXX with @entity454 on hemodialysis: a cross-sectional observational study.

@entity1 @entity1095 @entity101 @entity6 @entity7874 @entity730 @entity729 @entity340 @entity65 @entity454
BACKGROUND: This multicenter international cross-sectional observational study characterized vascular and @entity340 burden and correlations with pulse pressure, @entity6 , @entity101 , and @entity65 in prevalent hemodialysis @entity1 . METHODS: We enrolled 275 consecutive adults with @entity454 on maintenance hemodialysis for    3 months. Coprimary endpoints were prevalences of: (1) echocardiographic @entity730 in mitral valve, aortic valve or mitral annulus; (2) @entity729 by plain lateral lumbar X-ray. Correlations among @entity730 sites and with demographics and comorbidities were determined. Pulse pressures were determined. RESULTS: Subjects' mean        standard deviation (SD) age was 56        15.9 years; mean (SD) dialysis duration was 4.5        4.3 years. Overall, 100% of echocardiographically imaged @entity1 (n   =   243) had @entity730 in aortic valve, mitral valve, or mitral annulus; 77.8% of X-rayed @entity1 (n   =   248) had @entity730 . Radiographic @entity730 score correlated significantly with @entity730 of aortic valve (p   <   0.0001) and mitral annulus (p   =   0.0001) but not mitral valve. Aortic valve, mitral valve, and @entity730 correlated significantly among themselves (p   <   0.0001). Moderate/severe @entity7874 was significantly more prevalent in @entity1 aged    65 years than <65 years, @entity1 than @entity1 , and Whites than African Americans. Pulse pressure correlated significantly with @entity729 score (p   =   0.0049) but not with @entity340 at any site. CONCLUSIONS: Vascular and @entity340 are highly prevalent in the hemodialysis population. @entity1095 correlates significantly with elevated pulse pressure and can be assessed easily using lateral lumbar X-ray. Further studies investigating the interaction between pulse pressure and development or progression of @entity729 are of interest.
