Effect of modified Widman flap surgery and systemic XXXX on the subgingival microbiota of periodontal lesions.

@entity6730 @entity2868 @entity527 @entity23613 @entity2520 @entity6419 @entity3288 @entity885 @entity8211 @entity11625 @entity803 @entity2523
33 subjects with evidence of active @entity2520 were treated by modified Widman flap surgery and systemic @entity803 (1 g/day for 21 days). @entity527 samples were taken from 41 sites in 12 of these subjects before and 6 months after therapy for predominant cultivable microbiota studies. Mean pocket depth and attachment levels in the 41 sampled sites were 7.1 +/- 2.9 mm and 7.7 +/- 3.2 mm prior to therapy and 4.8 +/- 2.3 mm and 6.2 +/- 3.4 mm after therapy. @entity11625 and @entity23613 were more frequently detected in samples taken after therapy, while @entity2868 , S. morbillorum, @entity8211 and W. recta were less frequently detected after therapy. A. actinomycetemcomitans were detected in 7 sites pretherapy and 1 site post therapy. The frequency of detection of @entity2523 and @entity3288 was virtually unchanged. The mean levels of the Actinomyces sp., A. actinomycetemcomitans, @entity2523 , @entity3288 , S. morbillorum, @entity8211 and W. recta were decreased after therapy, while the mean levels of @entity11625 , @entity6419 , @entity885 II and @entity23613 were increased after therapy. @entity23613 showed the greatest increase to 8.2% of the microbiota. In the second phase of the study, @entity527 samples from 94 sites in the 33 treated subjects were analyzed by predominant cultivable techniques. As a result of therapy, 24 sites exhibited @entity6730 greater than 2 mm, 23 sites exhibited "gain" greater than 2 mm and the remaining 47 sites were considered to be unchanging.(ABSTRACT TRUNCATED AT 250 WORDS)
