Prevalence of Congenital @entity299 in XXXX with Orofacial Clefts: A Systematic Review.

@entity1 @entity13797 @entity15853 @entity299 @entity118 @entity3384
BACKGROUND: The reports on prevalence rates of @entity299 ( @entity299 ) in @entity1 with @entity13797 ( @entity13797 ) have varied widely. OBJECTIVE: To systematically review the prevalence rates of @entity299 in @entity1 with @entity13797 . MATERIAL AND METHOD: A computer search was conducted through the PubMed from 1950 to June 2015 using key words or search terms of @entity299 , @entity13797 , @entity3384 and prevalence. RESULTS: The search resulted in nine studies with 598 @entity299 cases identified in 5,707 @entity1 with @entity13797 . The prevalence of @entity299 in @entity1 with @entity13797 ranged from 3.9% to 23.9%. The five prospective studies had prevalence rates of 12.0% (95% confidence interval [CI]: 10.9 to 13.2) whilst the four retrospective studies had prevalence rates of 8.6% (95% CI: 7.5 to 9.8). Concerning the prospective studies, the newborn study had a higher prevalence than those of other childhood studies [23.9% vs. 11.5% (95% CI: 10.4 to 12.7)]. The newborn study with the use of echocardiography had a higher prevalence than those without using echocardiography (23.9% vs. 12.8%). @entity118 was the most frequent CHD found. CONCLUSION: CHD is commonly found in a @entity1 with @entity15853 . Echocardiography should be used to assess CHD in @entity1 with @entity13797 .
