Anti-m  llerian hormone, antral follicle count and ovarian volume predict menstrual cycle length in healthy XXXX .

@entity1 @entity230 @entity248
OBJECTIVE: Although menstrual cycle length is one of the main concerns of @entity1 and may have important health consequences, little is known about its predictors. The aim of this study was to identify predictors of menstrual cycle length variability in healthy @entity1 . DESIGN: Prospective cross-sectional study. @entity1 : 200 healthy @entity1 aged 21-45. MEASUREMENTS: A questionnaire was administered to determine lifestyle factors. Ovarian parameters, metabolic parameters, pituitary hormones, sex @entity230 , and anti- m  llerian hormone ( @entity248 ) were measured. RESULTS: @entity1 with long (>= 35 days) and normal (25-34 days) menstrual cycles had >5-fold and >2-fold higher serum @entity248 levels, respectively, compared to those with short cycles (<25 days). Menstrual cycle length was associated with age but not lifestyle factors. Only one factor group (- @entity248 , antral follicle count [AFC], ovarian volume, testosterone and LH) was significantly associated with menstrual cycle length. Within this factor group, only the ovarian parameters ( @entity248 , AFC, ovarian volume) predicted menstrual cycle length. Each SD increase in @entity248 (32.9 pmol/L) and ovarian volume (2.29 cm(3) ) was associated with 2.80-fold (95% CI: 1.67-4.69) and 1.62-fold (95% CI: 1.08-2.43) increased risks, respectively, for longer menstrual cycles. CONCLUSIONS: @entity248 , AFC, and ovarian volume are positively associated with menstrual cycle length in healthy @entity1 . Our identification of @entity248 as an independent predictor of menstrual cycle length puts forth a new notion of utilizing menstrual cycle length to predict possible @entity248 -dependent/associated outcomes. In addition, this novel relationship may facilitate the interpretation of @entity248 levels and its clinico-pathological significance across different centres. This article is protected by copyright. All rights reserved.
