Trends in lipid levels and @entity1007 in XXXX and normotensive finnish adults from 1982 to 1997.

@entity1 @entity101 @entity1007 @entity165
OBJECTIVES: To assess the trends in lipid levels and awareness of @entity1007 in @entity101 and normotensive population in Finland from 1982 to 97. DESIGN: Four independent cross-sectional population surveys conducted in 1982, 1987, 1992 and 1997. SETTING: The provinces of North Karelia and Kuopio in eastern Finland and the region of Turku-Loimaa in south-western Finland. SUBJECTS: @entity1 and @entity1 aged 25-64 years, selected randomly from the national population register. The subjects were classified to four groups according to their blood pressure level and treatment status: normotensive, unaware @entity101 , aware but not treated @entity101 and treated @entity101 . The total number of @entity1 was 24 083. MAIN OUTCOME MEASURES: We assessed the mean serum total @entity165 and HDL @entity165 concentrations, the prevalence of @entity1007 (total @entity165 >/=6.5 mmol L-1 or the use of lipid-lowering drugs), the prevalence of a high ratio of total @entity165 to HDL @entity165 (ratio >/=5) and the awareness of @entity1007 amongst the four study groups. RESULTS: Mean total @entity165 , the prevalence of @entity1007 and the prevalence of a high ratio of total to HDL @entity165 decreased, whereas the awareness of @entity1007 increased significantly in all study groups. The decline in mean total @entity165 was largest in treated @entity101 subjects of both sexes (13% in @entity1 , 14% in @entity1 ). Mean HDL @entity165 increased significantly in all study groups except in the unaware @entity101 @entity1 , but it remained significantly lower in treated @entity101 @entity1 in both sexes compared with the other groups (P < 0.001). CONCLUSIONS: The lipid profile of both the @entity101 and normotensive population has significantly improved in both the @entity101 and normotensive population in Finland from 1982-97. The introduction of newer antihypertensive drugs has not had any effect on the HDL @entity165 level amongst treated @entity101 @entity1 at the population level.
