Age-stratified normal values for prostate volume, XXXX , maximum urinary flow rate, IPSS, and other LUTS/BPH indicators in the German male community-dwelling population aged 50 years or older.

@entity1 @entity1067 @entity1486
PURPOSE: To establish age-stratified normal values for prostate volume, serum total @entity1486 concentration, maximum urinary flow rate (Q (max)), micturition and postvoid residual urine volumes, IPSS, and quality of life. These community-derived values of healthy older @entity1 are necessary to correctly judge @entity1 with lower urinary tract symptoms due to @entity1067 (LUTS/BPH). METHODS: Analysis of LUTS/BPH-related determinants in community-dwelling @entity1 in the city of Herne, Germany after exclusion of subgroups with co-morbidities or co-medications with possible influence on the key items. RESULTS: The analysis is based on 1,763 @entity1 . In these @entity1 aged 50-80 years, mean total prostate volume continuously increased from 24 to 38 cc and mean @entity1486 concentration from 1.1 to 2.5 ng/ml. @entity1486 concentration in @entity1 with a prostate volume <25 cc also showed a continuous increase with aging, starting at 0.8 in the youngest and ending at 1.9 ng/ml in the oldest age group. Mean Q (max) of free uroflowmetry (from 22.1 to 13.7 ml/s) and mean micturition volume (from 329 to 193 cc) showed a continuous decrease that was dependent on prostate size. Mean postvoid residual urine was nearly unchanged over the age groups at approximately 20-30 cc. Although IPSS increased continuously with aging (from 4 to 7), QoL remained unchanged at 2 over the age groups. Prostate size had a minor impact on IPSS. CONCLUSIONS: Normal values for investigated LUTS/BPH-related determinants and the influence of aging hereon should serve as references during the assessment of Caucasian @entity1 in Europe.
