XXXX : The Hazards of Corticosteroid Monotherapy.

@entity1 @entity1713 @entity1596 @entity228 @entity17577 @entity281
PURPOSE: To describe fulminant toxoplasma retinochoroiditis induced by @entity228 monotherapy. METHODS: Clinical records of nine @entity1 were reviewed. RESULTS: All @entity1 (five female, four male; aged 15-64 years) had been misdiagnosed as unilateral non-infectious @entity1596 and given systemic and/or local corticosteroid injections elsewhere. Mean disease duration before referral was 105.6    71 (45-240) days. Visual acuity at presentation was <20/200 in six eyes. Average lesion size was 6.6 disc areas in eight eyes and all four quadrants were involved in one. Toxoplasma DNA was detected in eight tested eyes. Mean duration of anti-toxoplasmic therapy was 92.5    37.1 days. Three eyes developed @entity1713 . Four @entity1 underwent pars plana vitrectomy. Final visual acuity was <20/200 in five eyes. CONCLUSIONS: Iatrogenic immunosuppression due to initial misdiagnosis may lead to an aggressive course and serious complications of @entity17577 , a potentially self-limiting @entity281 .
