XXXX ? A pilot study with confocal laser scanning microscopy.

@entity1 @entity75 @entity24113 @entity272 @entity4891 @entity4653
BACKGROUND: Differentiation of some @entity24113 ( @entity4891 ) lesions is a challenge. @entity4653 ( @entity4653 ) has been proved to be useful in the diagnosis of @entity272 ; however, to date, there is no report on the differential study of the two diseases with @entity4653 . OBJECTIVES: To obtain the @entity4653 image characteristics of SK and @entity4891 , and then test the differential ability of @entity4653 imaging. METHODS: We recruited 10 @entity1 with typical lesions of SK under @entity4653 images to validate the features reported. Another 10 @entity1 with typical @entity75 were also recruited, imaged with @entity4653 and biopsied to obtain the features under @entity4653 images based on histology analysis. Then, we attempt to summarize and refine those characteristics collected to obtain the most significant ones. All the cases with lesions suggestive of SK or @entity4891 were advised to undergo imaging with @entity4653 , and if @entity4653 imaging reflected discordantly with the clinical diagnosis, a biopsy was suggested for the exact lesion imaged. Those cases with @entity4653 and histology results were collected. Finally, two clinical dermatologists, who had no previous experience with @entity4653 , were tested with the simplified features of @entity4653 images to differentiate the suspected lesions of SK and @entity4891 among the cases collected. RESULTS: In total, there were 58 cases with @entity4653 images and histology results collected, in which, 40 cases were diagnosed as SK and 18 cases as @entity4891 by histology. The two blinded dermatologists' judgments were identical to histology analysis. CONCLUSION: @entity4653 proved to be valuable in the differential diagnosis of SK and @entity4891 . The simplified characteristics were easily understood and acceptable to those with no previous experience of @entity4653 .
