Definitive radiotherapy following prostatectomy: results and XXXX .

@entity1 @entity263 @entity1184 @entity4 @entity4272 @entity532 @entity3142
Thirty-four @entity1 with @entity263 treated by prostatectomy received postoperative external beam radiation. Sixteen @entity1 were treated within 4 months of radical prostatectomy (group 1), 12 @entity1 were treated for @entity263 following initial enucleative prostatectomy for benign @entity1184 (group 2) and 6 @entity1 were treated for palpable local recurrence 4 to 10 years following radical prostatectomy (group 3). The indications for postoperative radiotherapy following radical prostatectomy included extracapsular extension, seminal vesicle invasion, peri-prostatic soft tissue involvement, positive margins or palpable local recurrence. Eighty-five percent of the @entity1 received whole pelvic radiation. All @entity1 then had a 2-week treatment rest followed by a reduced portal to the prostate bed to a dose of 6500 cGy. The local control rate after radiotherapy was 100% with a median follow-up of 4 years. The 5-year actuarial survival and disease-free survival rates for all @entity1 were 82 and 72%, respectively. In group 1, the 5-year actuarial survival and disease-free survival rates were 100 and 91%, respectively. In group 2, these rates were 77 and 64%. Three of the six @entity1 in group 3 died within 30 months of radiotherapy. Fourteen @entity1 (41%) had mild to moderate treatment related symptoms including seven @entity1 (21%) with lower @entity4 , five @entity1 (15%) with @entity3142 , two @entity1 (6%) with urethral stricture and three @entity1 (9%) with @entity4272 . Six of eight @entity1 who were potent prior to radiation retained potency thereafter. No severe @entity532 occurred. We conclude that external beam radiation therapy administered after prostatectomy resulted in an acceptable therapeutic ratio with 100% local regional control, and an acceptable complication rate (41%).
