Spinal anaesthesia with adjunctive intrathecal @entity1286 versus continuous lumbar plexus blockade: a randomised comparison for XXXX after hip replacement.

@entity1 @entity26 @entity4784 @entity1337 @entity16 @entity111 @entity1286 @entity158 @entity282
Following elective total hip replacement, both continuous lumbar plexus blockade and spinal anaesthesia (with adjunctive intrathecal @entity1286 ) have shown early outcome benefits over opioid @entity1337 and single-injection nerve block. However, the two techniques have not been compared in a prospective randomised manner. Our study examined 50 @entity1 undergoing elective hip joint replacement who were randomised to receive spinal anaesthesia (with adjunctive intrathecal @entity1286 0.1 mg) or @entity1 -controlled continuous lumbar plexus blockade. All surgery was conducted under general anaesthesia. Measured outcomes included numerically rated @entity282 , @entity4784 and indices of mobilisation together with complications. Results show that block placement time was marginally shorter for the spinal group (5 versus 7 minutes, P=0.01). The primary outcome, @entity158 on movement/mobilisation during the first 24 hours, was not statistically significantly different between groups. @entity1 in the lumbar plexus group were given more intraoperative opioid and rescue @entity1286 in the post-anaesthesia care unit (median = 4 versus 0 mg, P <0.001), with correspondingly higher @entity158 scores (median 5/10 versus 0/10, P <0.001). @entity158 scores during the subsequent 24 hours were similar between groups, but more @entity1 in the spinal group were given rescue @entity1286 (5 versus 0, P=0.02). Physiotherapy mobilisation indices appeared similar between groups. More spinal group @entity1 reported @entity111 (12 versus 5, P=0.01), but antiemetic requirements, episodes of disorientation, arterial @entity26 desaturation and falls were all similar between groups. Postoperative symptoms suggestive of @entity16 or injury did not differ between groups. We found that following elective hip joint replacement, compared to continuous lumbar plexus blockade, spinal anaesthesia incorporating adjunctive intrathecal @entity1286 did not result in a statistically significant difference in @entity158 on movement/mobilisation during the first 24 hours, although it was associated with better @entity1337 in the post-anaesthesia care unit. Subsequently, however, these @entity1 appeared to require more rescue @entity1286 and more of them reported @entity111 .
