Mild @entity2332 preserves @entity550 after resuscitation in a XXXX model of @entity1167 .

@entity1 @entity455 @entity550 @entity26 @entity772 @entity1585 @entity2224 @entity1167 @entity35 @entity2332
OBJECTIVE: Mild @entity2332 improves the outcomes of @entity772 @entity1 after @entity1167 . Its neuroprotective mechanism is not fully understood. We investigated the effects of mild @entity2332 on @entity550 and cerebral @entity26 extraction ratio. METHODS: Twenty-five @entity35 were randomized into the @entity1585 ( @entity1585 ), normothermic group (NT) or the sham control group. @entity2224 was electrically induced and untreated for 8 mins, followed by 8 mins of precordial compressions and mechanical ventilations. The core temperature in the @entity1585 group was reduced to 33  0.5  C at 14 mins after ROSC with a combination of ice packs, an electrical fan and a cooling blanket. The temperature was maintained at 33  C for 8hrs. Hemodynamics, @entity455 and @entity550 were measured at baseline, 2, 4 and 8hrs after ROSC. RESULTS: Microvascular flow index was significantly reduced in the NT and @entity1585 groups when compared with the SC group. A significant lesser reduction in microvascular flow index was observed in the @entity1585 group when compared with the NT group. Mild @entity2332 reduced the cerebral @entity26 extraction ratio after resuscitation when compared with the NT group. CONCLUSION: Mild @entity2332 improves the cerebral cortex microcirculatory blood supply/ @entity26 uptake mismatching after resuscitation. This may provide an additional cerebral protection.
