XXXX leads to adequately increased erythropoiesis in asymptomatic Kenyan @entity1 .

@entity1 @entity32 @entity417 @entity9230 @entity69 @entity1307 @entity281 @entity311 @entity4765 @entity68
@entity417 is associated with a shift in @entity68 distribution from functional to storage compartments. This suggests a relative deficit in @entity1307 production or action similar to that observed in other infections. Our study in Kenyan @entity1 with asymptomatic @entity311 aimed at investigating whether @entity311 causes increased erythropoiesis, and whether the erythropoietic response appeared appropriate for the degree of resulting @entity417 . Longitudinal and baseline data were used from a trial with a 2 x 2 factorial design, in which 328 anemic Kenyan @entity1 were randomly assigned to receive either @entity68 or placebo, and @entity9230 - @entity4765 or placebo. Erythropoiesis was evaluated by serum concentrations of @entity1307 and soluble @entity69 receptor. Prospectively collected data showed that @entity281 resulted in decreased hemoglobin concentrations, and increased serum concentrations of @entity1307 and @entity69 receptor. Conversely, disappearance of malarial antigenemia resulted in increased hemoglobin concentrations, and decreased concentrations of these serum indicators. Additionally, our baseline data showed that current or recent @entity281 is associated with increased serum concentrations of @entity1307 and @entity69 receptor, and that these were as high as or perhaps even higher than values of @entity1 without @entity281 and without @entity32 . Our findings indicate that in asymptomatic @entity311 , the erythropoietic response is adequate for the degree of @entity417 , and that @entity32 probably plays no or only a minor role in the pathogenesis of the resulting @entity417 . Further research is needed to demonstrate the role of deficient @entity1307 production or action in the pathogenesis of the @entity417 of symptomatic @entity311 .
