Emerging links between non-neurogenic lower urinary tract symptoms secondary to benign prostatic obstruction, XXXX and its components: A systematic review.

@entity1 @entity2298 @entity28 @entity209 @entity1876
UNASSIGNED: We carried out a systematic review in order to determine the connection between lower urinary tract symptoms secondary to @entity1876 and @entity209 with its components. We searched the Cochrane Central Register of Controlled Trials, PubMed, EMBASE, the Cochrane Database of Systematic Review and Web of Science from their inception until January 2015 to identify all eligible studies on the effect of @entity209 (or component factors) on the presence or severity of lower urinary tract symptoms/ @entity1876 in @entity1 . This analysis was carried out according to the STrengthening the Reporting of OBservational studies in Epidemiology guidelines. In total, 19 studies were identified as eligible for this systematic review. The quality assessment score was >= 50% in more than half of the studies (11/19). The evidence synthesis showed a positive association between @entity209 , number of components and lower urinary tract symptoms/ @entity1876 . In particular, the major endocrine aberrations of this connection are central @entity28 and @entity2298 . The links between insulin resistance and lower urinary tract symptoms/ @entity1876 should be better investigated. Ethnic disparities in all examined studies showed a different impact of @entity209 on lower urinary tract symptoms/ @entity1876 severity and such influence still remain unclear. The relationship between @entity209 and lower urinary tract symptoms/ @entity1876 open the way for introducing physical activity and diet as recognized first-line interventions for treating lower urinary tract symptoms. However, this connection should be investigated in two different ethnic cohorts (i.e. Asian vs Caucasian) in order to better understand the impact of ethnic disparities on @entity209 and lower urinary tract symptoms/ @entity1876 severity.
