[The study of washing operative wound with XXXX solution in the orthopedic surgery].

@entity1 @entity8 @entity4509 @entity86 @entity4028
For the purpose of preventing @entity86 , investigation was carried out on effectiveness and safety of @entity4509 (AMK) after washing wound surface with its solution. 500 ml saline solution containing 400 mg AMK was used for washing. As the result, no @entity86 were observed in all the 19 @entity1 operated in our department. Neither abnormal findings to be regarded as abnormalities in blood test nor side-effects caused by washing were also observed. The blood samples obtained after washing did not show measurable AMK in all cases. It is said that use of antibiotics with 1) a wide-range of spectrum, 2) a bactericidal action and 3) low cross resistance against other antibiotics is preferable in washing wound surface in order to prevent @entity86 . Under these circumstances, administration of @entity4028 antibiotics is used frequently. Concerning the use of @entity4028 antibiotics, however, it is necessary to pay @entity8 . The previous study has revealed that AMK is lower in auditory and @entity8 than other @entity4028 antibiotics. AMK is thought, therefore, to be free from fear of auditory and @entity8 after washing and also to be one of effective antibiotics.
