[Primary malignant T-cell-rich XXXX of the central nervous system: a case report].

@entity1 @entity1032 @entity66 @entity706 @entity1313 @entity1269 @entity5 @entity1892 @entity5855 @entity1662
An autopsy case of primary intracranial T-cell-rich @entity1892 in a 69-year-old female is presented. The @entity1 was admitted with a diagnosis of a @entity1313 in July 1993 and a month long history of @entity1032 , motor weakness of the right arm and leg, and a tendency toward somnolence. Neurological examination revealed disturbance of @entity1662 , @entity1269 , and papilloedema. However, her general physical examination was unremarkable. A CT scan and MR imaging revealed an irregular enhanced @entity66 at the paraventricular deep white matter in the bilateral parieto-occipital lobe. The @entity1 was treated with surgical biopsy of the @entity5 followed by combined radiotherapy (a total of 50 Gy) and chemotherapy. Following repetitive episodes of remission and exacerbation, the @entity1 expired about seven months after the onset of symptoms. Histopathological diagnosis of the @entity5 was @entity706 (diffuse medium-sized cell type). In the immunohistochemical study, most of the @entity706 cells had T-cell markers, such as @entity5855 . Some of the @entity706 cells were L26-positive. Neither glial fibrillary acidic protein nor neuron specific enolase were reactive with the @entity706 cells. At post-mortem examination, the specimens disclosed diffuse infiltration of medium-sized @entity706 cells. By contrast, most of the @entity706 cells were shown to be positive by the analysis of L26. None of the @entity706 cells exhibited the presence of @entity5855 . These immunohistochemical evaluations conform to the criteria of T-cell-rich @entity1892 .
