The CAHP ( @entity1167 Hospital Prognosis) score: a tool for risk stratification after out-of-hospital XXXX .

@entity1 @entity1425 @entity944 @entity1167
AIMS: Survival after out-of-hospital @entity1167 (OHCA) remains disappointingly low. Among @entity1 admitted alive, early prognostication remains challenging. This study aims to establish a stratification score for @entity1 admitted in intensive care unit (ICU) after OHCA, according to their neurological outcome. METHODS AND RESULTS: The CAHP ( @entity1167 Hospital Prognosis) score was developed from the @entity944 Expertise Center registry (Paris, France). The primary outcome was poor neurological outcome defined as Cerebral Performance Category 3, 4, or 5 at hospital discharge. Independent prognostic factors were identified using logistic regression analysis and thresholds defined to stratify low-, moderate-, and high-risk groups. The CAHP score was validated in both a prospective and an external data set (Parisian @entity1167 Registry). The developmental data set included 819 @entity1 admitted from May 2011 to December 2012. After multivariate analysis, seven variables were independently associated with poor neurological outcome and subsequently included in the CAHP score (age, non-shockable rhythm, time from collapse to basic life support, time from basic life support to return of spontaneous circulation, location of @entity1167 , @entity1425 dose, and arterial pH). Three risks groups were identified: low risk (score  <=150, 39% of unfavourable outcome), medium risk (score 150-200, 81% of unfavourable outcome) and high-risk group (score >= 200, 100% of unfavourable outcome). The AUC of the CAHP score were 0.93, and the discrimination value in the validation data sets was consistent (respectively, AUC 0.91 and 0.85). CONCLUSION: The CAHP score represents a simple tool for early stratification of @entity1 admitted in ICU after OHCA. A high-risk category of @entity1 with very poor prognosis can be easily identified.
