[Use of thrombolytic therapy and rheolytic thrombectomy in treatment of XXXX ].

@entity1 @entity358 @entity1151
UNASSIGNED: The article deals with the results of combined treatment of @entity1 with @entity1151 by means of systemic thrombolytic therapy, anticoagulant therapy, and rheolytic thrombectomy during the period from 2012 to 2013. Thrombolytic therapy was used in 78 of 187 @entity1 with the confirmed diagnosis of @entity1151 (Group 1). The diagnosis was verified and therapeutic results were controlled by means of contrast-enhanced spiral computed tomography and perfusion scintigraphy. Thrombolysis was carried out using: tissue plasminogen activator - alteplase (61 cases) with administration of the full dose during 2 hours, streptokinase (14 cases) at a dose of 1.5 million IU in the mode of prolonged infusion during 24 hours and urokinase (3 cases) at a dose of 4400 IU/kg during 12 hours. 109 @entity1 were subjected to anticoagulant therapy (Group 2). Five @entity1 were subjected to rheolytic thrombectomy for desobstruction of the pulmonary artery. The method was used in @entity1 with previously performed ineffective or partially effective thrombolytic therapy, as well as in @entity1 with contraindications to thrombolysis. The lethality rate for TLT amounted to 5.4% and that for anticoagulant therapy 26.6%. Probability of a lethal outcome in Group 2 (anticoagulant therapy) turned out to be 6.71 times higher as compared with Group 1 (thrombolytic therapy). In all cases of using rheolytic thrombectomy we managed to achieve a decrease of the Miller index and systolic pressure in the pulmonary artery. @entity358 was complete in 3 cases. In two cases rheolytic thrombectomy was partially effective and the @entity1 underwent repeat thrombolysis with a good clinical outcome. Using systemic thrombolysis in @entity1 with @entity1151 demonstrated a positive effect on the prognosis of survival. Rheolytic thrombectomy contributed to improvement of the results of thrombolytic therapy and may be used as an alternative method of treatment.
