Analysis of Choroidal Thickness Using Spectral-Domain OCT in XXXX With Unilateral Amblyopia.

@entity1 @entity2194 @entity9340 @entity3193 @entity4457
PURPOSE: To compare the subfoveal, parafoveal, and peripapillary @entity2194 with those of fellow and control eyes. METHODS: This institutional study involved 114 eyes from 38 @entity1 with unilateral @entity4457 and 19 healthy @entity1 , aged 6 to 17 years. The cause of @entity4457 was identified as hyperopic @entity9340 in 17 cases and strabismus in 21 cases. All @entity1 underwent central macular thickness (CMT) and @entity3193 at seven retinal sites with spectral-domain optical coherence tomography (OCT). Statistical analysis was performed to compare the CMT and @entity2194 with control eyes. RESULTS: Average CMT was 248.31    24.18  m in amblyopic eyes, 249.76    26.08  m in fellow eyes, and 243.65    31.96  m in controls (P = .604). Average subfoveal choroidal thickness was 394.15    71.03  m in amblyopic eyes, 356.07    79.93  m in fellow eyes, and 319.44    87.29  m in controls (P = .000). The choroidal thickness of the subfoveal area and at 750- m intervals temporal and nasal to the fovea was significantly thicker in amblyopic eyes than in controls (P < .05). The choroidal thickness was significantly thicker in amblyopic eyes than in fellow eyes only at 750  m nasal to the fovea. Type and depth of @entity4457 did not differ significantly between foveal or parafoveal choroidal thickness (P > .05). There was a significant negative correlation between the nasal peripapillary choroidal thickness and the axial length in the amblyopic eyes (r = -0.37, P = .022). The choroidal thickness in the peripapillary area was not significantly different in the three groups (P > .05). CONCLUSIONS: This study demonstrated that choroidal thickness can be measured by spectral-domain OCT in @entity1 with @entity4457 . Subfoveal @entity2194 was significantly thicker than in control eyes. The amblyopic process may involve the choroid, but not the macula. However, further evaluation is needed.
