Functional residual capacity and static compliance during the first year in preterm XXXX treated with surfactant.

@entity1 @entity649 @entity1030
Individual lung development during the first year of life was studied in surfactant treated preterm @entity1 with @entity649 ( @entity649 ) and healthy controls, as well as in a group who subsequently developed @entity1030 ( @entity1030 ). Lung development was assessed from functional residual capacity (FRC) and compliance of the respiratory system (Crs). Twenty-one @entity1 with @entity649 after preterm birth received surfactant treatment. Six of them developed @entity1030 . Eighteen preterm @entity1 without @entity649 served as a control group. Lung function measurements were performed at term age and 4, 8, and 12 months afterwards. FRC was obtained by means of the closed-system helium dilution technique whereas static Crs was obtained by means of the weighted spirometer technique. At term age, FRC was lower in the @entity1030 group compared with uncomplicated @entity649 and controls (p < 0.05). No significant differences between groups were found in the development of FRC during the first year of life (p = 0.4). No differences were found in Crs during the first year of life in surfactant treated @entity1 who recovered from uncomplicated @entity649 and the control group. However, lower values were found in the @entity1030 group (p < 0.05). We conclude that surfactant treated @entity1 without @entity1030 have similar lung development during the first year of life as control preterm @entity1 .
