Fine-needle aspiration cytology guided by endoscopic ultrasonography: results in 141 XXXX .

@entity1 @entity788 @entity75 @entity5 @entity344
BACKGROUND AND STUDY AIMS: Diagnosis of @entity75 , @entity788 , and mediastinal or celiac lymph nodes or masses is possible using endoscopic ultrasonography (EUS), but histological confirmation to differentiate between benign and @entity5 is still required. The aim of this study was to evaluate the efficacy of a new method of EUS-guided fine-needle aspiration biopsy of intramural and @entity75 . @entity1 AND METHODS: From October 1991 to September 1994, EUS-guided fine-needle aspiration biopsy was carried out in 141 @entity1 with findings of mediastinal masses (18 cases), mediastinal lymph nodes (24 cases), @entity5 (seven cases), celiac lymph nodes (26 cases), large gastric folds with negative endoscopic biopsy (13 cases), @entity788 (43 cases), a small liver metastasis (five cases), @entity5 (four cases), and an adrenal metastasis (one case). The EUS examination was performed using a Pentax-Hitachi FG 32-UA system. RESULTS: A malignant @entity5 was diagnosed in 110 of the 141 @entity1 . EUS-guided fine-needle aspiration was positive in 85 cases. In 15 cases, an adequate specimen could not be obtained (10.6%). The sensitivity and specificity of the diagnosis of @entity5 were 77.0% and 100%, respectively. Results were better for mediastinal masses (sensitivity 88%), mediastinal lymph nodes (81%), and celiac lymph nodes (80%) than for @entity788 (75%) or @entity5 (60%). CONCLUSIONS: These results suggest that EUS-guided fine-needle biopsy using a curved-array transducer represents a step forward in the tissue diagnosis of @entity344 .
