Amniotic fluid @entity1421 in pregnancies complicated by XXXX .

@entity1 @entity32 @entity2907 @entity650 @entity1421 @entity5870 @entity13493
OBJECTIVE: To determine amniotic fluid @entity1421 concentrations in @entity1 @entity13493 ( @entity13493 ) with respect to microbial invasion of the @entity2907 (MIAC), @entity32 (IAI), microbial-associated IAI, histological @entity5870 , and short-term neonatal morbidity. METHODS: One hundred forty-five @entity1 with singleton pregnancies were included in this study. Amniotic fluid samples were obtained by transabdominal amniocentesis and were assayed for @entity1421 concentrations by ELISA. IAI was defined as amniotic fluid @entity650 > 745 pg/mL. Microbial-associated IAI was defined as the presence of both MIAC and IAI. RESULT: No differences in @entity1421 concentrations were found between @entity1 with and without MIAC (p=0.27). @entity1 with IAI (p=0.0008) and microbial-associated IAI (p=0.01) had higher @entity1421 concentrations than @entity1 without these complications. @entity1 with histological @entity5870 had higher @entity1421 concentrations only in crude analysis (p=0.02), but not after adjustment for gestational age at sampling (p=0.10). No associations between amniotic fluid @entity1421 concentrations and the selected conditions of severe neonatal morbidity were found. CONCLUSIONS: The intraamniotic inflammatory response either to infectious or to non-infectious stimulus, but not microbial invasion of the @entity2907 per se, seems to be a main factor associated with the elevation of the amniotic fluid @entity1421 concentrations in @entity1 with @entity13493 .
