[Efficacy analysis of different follow-up methods in detecting first recurrence of XXXX ].

@entity1 @entity5 @entity706
OBJECTIVE: This study aimed to evaluate the value of different follow-up methods for the detection of first recurrence in @entity706 @entity1 in first complete remission (CR), and to find reasonable long-term follow-up strategies. METHODS: We retrospectively analyzed 277 @entity706 @entity1 who achieved CR after first-line therapies and subsequently relapsed. All @entity1 were divided into routine surveillance imaging group (group A) and irregular imaging follow-up visit group (group B). To compare the two groups of @entity1 with @entity5 burden ( @entity5 diameter and number of @entity5 invasion areas) at the time of relapse, and the number of imaging scans before the relapse. To analyze the main ways of finding @entity706 in the two groups. RESULTS: Among a total of 277 @entity1 , there were 187 @entity1 in the group A and 90 @entity1 in the group B. The @entity5 recurrence occurred in 120 cases (43.3%) within the first year, and 76 @entity1 (27.4%) in the second year. At the time of diagnosis of recurrence, the average maximum diameter of @entity5 in the groups A and B were (3.2    2.2) cm and (3.8    2.9) cm, respectively (P = 0.123). The two groups showed slight difference in number of @entity5 invasion areas (P = 0.050). At the time of diagnosis of recurrence, there were 3 of 121 @entity1 (2.5%) with maximum diameter of @entity5 more than 8 cm in the group A and 6 of 49 cases (12.2%) in the group B (P = 0.018). In the group A, the @entity1 had in average 4.9 times of imaging scans before recurrence, significantly more than the 0.22 times in the group B (P < 0.001). Among all @entity1 , the diagnosis of recurrence was based on imaging scans only in 59 @entity1 (21.3%). CONCLUSIONS: @entity706 @entity1 do not benefit from routine surveillance imaging to detect the @entity5 recurrence. It indicates that we should not rely solely on imaging examinations at follow-up visits, and should pay more attention on clinical signs and symptoms.
