[Significance of intracellular cytokines levels in peripheral lymphocytes for evaluation of surgical stress after hepatectomy in XXXX with @entity157 ].

@entity1 @entity650 @entity5 @entity409 @entity418 @entity157 @entity356
It is difficult to evaluate surgical stress of @entity1 with @entity157 ( @entity157 ). Cytokine production from the liver is decreased due to the @entity409 that is usually associated with HCCs. Therefore, we evaluated surgical stress after hepatectomy by measuring intracellular cytokines of lymphocytes in peripheral blood. We examined 22 @entity1 with @entity5 (8 with @entity157 , 10 with @entity356 , and 4 with @entity418 ). The concentrations of serum @entity650 levels 6 h after hepatectomy, gastrectomy, and esophagectomy were 268 +/- 84, 309 +/- 93, and 1,323 +/- 364 pg/ml, respectively. There was no significant difference between hepatectomy and gastrectomy, though based on clinical observations, it is estimated the surgical stress of hepatectomy was greater than that of gastrectomy. Conversely, the percentage of CD4+ @entity650 + cells 6 h after surgery was 8.5 +/- 2.8, 3.3 +/- 0.6, and 7.8 +/- 3.4%, respectively. The percentage of CD4+ @entity650 + cells after hepatectomy was significantly higher than that after gastrectomy. We estimated that the percentage of CD4+ @entity650 + cells was an appropriate indicator of surgical stress on @entity157 , because the percentage of CD4+ @entity650 + cells correlated well with the duration of surgery more than did the serum @entity650 levels. These results suggest that the percentage of CD4+ @entity650 + cells may help in accurately evaluating surgical stress in @entity1 with @entity409 such as @entity157 .
