Clinical characteristics of XXXX treated with castellani solution.

@entity1 @entity75 @entity11477 @entity1776
Aim of the study is to observe clinical manifestations of @entity1776 ( @entity1776 ) treated with castellani solution. Twenty-four @entity1 (18 @entity1 and 6 @entity1 ; mean age, 49.7 years; range, 9-77 years) diagnosed with @entity1776 and treated with castellani solution were enrolled retrospectively. Topical treatment using castellani solution with or without curettage of a granular lesion and serial otoendoscopy-aided photographic documentation of the tympanic membrane were performed. Outpatient follow-up period ranged from 3 to 72 months and the mean follow-up period was 14.4 months. @entity1776 was classified into marginal/non-marginal type and ulcerative/polypoid subtype using a new scale. According to the scale used in this study, the marginal and ulcerative @entity1776 was the predominant type of @entity75 . Bacterial cultures of ear discharges from 19 @entity1 revealed Staphylococcus, Corynebacterium and @entity11477 in 12, 5, and 1 @entity1 , respectively and no growth of bacteria in one @entity1 . Of 24 @entity1 , 23 showed complete resolution of @entity1776 after treatment with castellani solution. However, one @entity1 had a persistent, small, dry, deepithelialized lesion and eight others required more than 3 months for complete recovery owing to a persistent residual lesion. There was recurrence in two @entity1 but the lesion resolved after additional castellani treatment. Topical application of castellani solution is a simple and effective treatment for @entity1776 . This study suggests a potential of castellani solution for treatment of @entity1776 with a serial photographic documentation and novel classification scale for description of lesions. A sufficiently long follow-up period is essential to confirm a complete recovery of @entity1776 .
