Perinatal management of XXXX associated with anti-group A antibody.

@entity1 @entity932 @entity882 @entity229 @entity16978 @entity204
OBJECTIVE: To prevent @entity16978 due to anti-group A antibody perinatal management was performed. BACKGROUND: We previously reported a case of severe @entity932 associated with @entity16978 due to anti-group A isoantibody. MATERIAL/METHODS: A 40-year-old Japanese @entity1 , gravida 4 para 1, was pregnant with her second baby. The previous sibling developed severe @entity882 and died 10   days after birth due to @entity932 . He was diagnosed with @entity16978 ; the causative antibody was found to be the anti-group A antibody. @entity229 was started at 7   weeks' gestational age. Intravenous immunoglobulin 1   g   kg(-1)    week(-1) was started at 29   weeks' gestational age and continued to delivery. Serological studies and genotyping were performed. RESULTS: The second @entity1 was delivered at 33   weeks' gestational age by caesarean section. He was discharged without @entity932 or @entity882 . The anti-group A antibody titre in the maternal serum was 2048-4096 (normal range: 4-64). The anti-group A antibody titre in the newborn's serum was 4. Cross-matching between the maternal serum and the paternal platelets was positive. CONCLUSION: Owing to the history of @entity16978 causing @entity932 and @entity204 of the previous sibling, strict follow-up of the subsequent pregnancy was conducted.
