Application of 256-channel dense array electroencephalographic source imaging in presurgical workup of XXXX .

@entity1 @entity410 @entity1315 @entity302 @entity72187
OBJECTIVE: This study evaluated the localization precision of 256-channel dense array electroencephalographic source imaging ( @entity72187 ) in comparison to conventional noninvasive tools. In addition, the study was designed to analyze the relationship between the 256-channel @entity72187 source patterns and surgical outcome. METHODS: Forty-three @entity1 with @entity1315 ( @entity1315 ) who underwent one-stage resective surgeries were recruited in this study. We compared @entity72187 with other noninvasive evaluation methods by comparing results with resections that eliminate or significantly reduced @entity410 according to sub-lobule and lobule criteria. Sensitivity and specificity of multiple evaluation methods were calculated. Kaplan-Meier analysis was performed to evaluate the relationship between source patterns and surgical outcome. RESULTS: @entity72187 showed the best sensitivity (sub-lobule, 91.4%; lobule, 97.1%) and specificity (75%) for both sub-lobule and lobule criteria. The Kaplan-Meier survival analysis showed that cases with "single source" had better prognosis than with "multiple sources" (p<0.05); cases of "sources within resection" showed better surgical prognosis than cases of "sources outside resection" (p<0.05). CONCLUSION: In this study, 256-channel @entity72187 provided a higher clinical yield than the other most broadly used noninvasive presurgical workup tools. @entity72187 results with "single source" correlated strongly to good prognosis, while cases with "multiple sources" may cautiously be considered as candidates for one-stage resective surgeries. The resection of the irritative zone identified by @entity302 ( @entity302 ) was related to good surgical prognosis in @entity1315 . SIGNIFICANCE: In the presurgical workup of @entity1315 , the clinical yield of 256-channel @entity72187 is high. Patterns of @entity72187 results are related to surgical prognosis, and they can be instructive for presurgical planning. The resection of the irritative zone can be related to good surgical prognosis in @entity1315 .
