XXXX as a predictor of complications in @entity5 @entity1 undergoing inguinal lymph node dissection.

@entity1 @entity66 @entity39 @entity5 @entity260 @entity6288 @entity281
PURPOSE: Lymphadenectomy (LND) is part of the surgical management of @entity5 but causes significant perioperative morbidity. We determined whether @entity6288 , a novel marker of nutritional status, is a predictor of @entity260 after LND. MATERIALS AND METHODS: Seventy-nine @entity1 underwent LND for @entity5 from 1999 to 2014, and 43 had available preoperative abdominal imaging. Skeletal muscle index (SMI) was calculated on axial computed tomography images at the third lumbar vertebrae, and an SMI of 55  cm(2)/m(2) was used to classify @entity1 as sarcopenic versus not. This classification was then correlated with @entity260 and survival. RESULTS: Median lumbar SMI was 54.7  cm(2)/m(2) with 22 (51.2  %) @entity1 categorized as sarcopenic versus 21 (48.8  %) who were not. Twenty-seven @entity260 occurred in 20 @entity1 within 30  days, of which 11 (40.7  %) were major (Clavien score  >= IIIa) and 16 (59.3  %) were minor. The most common complications were wound dehiscence (25.9  %), wound @entity281 (18.5  %), lymphocele (18.5  %), and flap @entity39 (14.8  %). On univariate analysis, the presence of @entity6288 , @entity66 , and lymphovascular invasion were predictors of @entity260 . On multivariate analysis, only @entity6288 was an independent predictor of 30-day complications [p  =  0.038; 95  % confidence interval (CI) 1.1-21.1]. Although @entity6288 was not statistically associated with worse overall survival (OS), there was a trend toward poorer outcomes in these @entity1 . CONCLUSIONS: @entity6288 can be a useful prognostic tool to predict the likelihood of @entity260 after LND for @entity5 . Preoperative nutritional supplementation may help reduce complication rates in the future.
