The epidemiology of XXXX as detected by spectral-domain optical coherence tomography: the beaver dam eye study.

@entity1 @entity227 @entity231 @entity6 @entity1713 @entity2994 @entity45 @entity989 @entity1020
PURPOSE: To describe the prevalence and interrelationships of epiretinal membranes (ERMs), vitreomacular traction (VMT), @entity1020 , @entity45 ( @entity45 ), lamellar macular holes (LMHs), full-thickness macular holes (FTMHs), and @entity227 in a population-based study of older adults. DESIGN: Cross-sectional study. @entity1 : There were 1913 @entity1 aged 63 to 102 years at the 20-year Beaver Dam Eye Study follow-up examination in 2008-2010, of whom 1540 (2980 eyes) had gradable spectral-domain optical coherence tomography (SD OCT) scans of the macula in at least 1 eye. METHODS: The presence of ERMs and other @entity989 was determined by standardized grading of macular SD OCT scans and photographs of 3 standard fields. MAIN OUTCOME MEASURES: Epiretinal membranes, VMT, @entity1020 , @entity45 , LMHs, FTMHs, and @entity227 . RESULTS: By using SD OCT, the prevalence of ERMs (34.1%), VMT (1.6%), @entity1020 (5.6%), @entity45 (20.0%), LMHs (3.6%), and FTMHs (0.4%) was estimated. The prevalence of @entity1020 (P < 0.001), ERMs (P < 0.001), and VMT (P = 0.005) increased with age; the prevalence of @entity45 (P = 0.05) decreased with age; and the prevalence of LMHs was not associated with age (P = 0.70). The prevalence of @entity1020 , LMHs, and ERMs was higher in eyes with a history of @entity231 surgery. Macular cysts and ERMs were more common in eyes with @entity989 , such as @entity6 , @entity2994 , and @entity1713 , than in eyes without these conditions. Macular cysts, ERMs, and FTMHs were associated with @entity227 . While adjusting for age and sex, @entity1020 (odds ratio [OR], 3.96; P < 0.0001), @entity45 (OR, 1.45, P = 0.007), LMHs (OR, 10.62; P < 0.001), VMT (OR, 2.72, P = 0.01), and @entity227 (OR, 3.23; P < 0.001) were more frequent in eyes with ERMs compared with eyes without ERMs. CONCLUSIONS: Epiretinal membranes are associated with @entity1020 , @entity45 , LMHs, VMT, and @entity227 . Further follow-up will allow better understanding of the natural history of ERMs and VMT and their relationships to the development of @entity1020 and LMHs in the aging population.
