Investigation of XXXX , IMP, NDM-1, @entity24197 AND OXA-48 enzymes in Enterobacteriaceae strains.

@entity2892 @entity2889 @entity24197 @entity2277 @entity2893 @entity580 @entity6543
Gram-negative bacteria especially Enterobacteriaceaespecies have become an increasing etiologic agent of @entity580 . The development of resistance to carbapenems have become an increasing problem in the treatment of @entity580 . Especially carbapenamases are common for Enterobacteriaceae strains. This study was performed to detect the types of carbapenemases in Enterobacteriaceaestrains isolated from various clinical samples. Enterobacteriaceae species were isolated from urine, blood, tracheal aspirates, wound, and other respiratory samples. Susceptibility of isolates to @entity2892 , @entity2889 and @entity6543 was tested. Carbapenemase genes were studied using HyplexSuperBug ID kit. @entity2277 (1-13), IMP (1-22), NDM-1, @entity24197 (1-10) and OXA-48 genes were investigated. Ninety-five isolates of Enterobacteriaceae spp. were included in the study. Sixty isolates were resistant to @entity2892 , @entity2889 and @entity6543 and 20 isolates were found resistant to @entity2892 or @entity6543 while 15 were susceptible to all carbapenems. Among the isolates with @entity2893 resistance, 57 were positive for one carbapenemase gene and susceptible isolates did not have carbapenemase gene. OXA-48 was found in 49 of the isolates (86%), NDM-1 in 6 (10.5%) isolates, @entity2277 in 2 isolates. IMP and @entity24197 gene loci were not identified. Carbapenemase genes play a crucial rolein the development and spread of resistant strains.
