Stressful life events predict XXXX relapse following remission: six-year prospective outcomes.

@entity1 @entity7027 @entity146 @entity2613 @entity1277 @entity1279 @entity1314
OBJECTIVE: To examine prospectively the natural course of @entity1279 ( @entity1279 ) and @entity1277 not-otherwise-specified (EDNOS) and test for the effects of @entity7027 ( @entity7027 ) on relapse after remission from these @entity1277 . METHOD: 117 female @entity1 with @entity1279 (N = 35) or EDNOS (N = 82) were prospectively followed for 72 months using structured interviews performed at baseline, 6- and 12-months, and then yearly thereafter. @entity2613 were assessed with the structured clinical interview for DSM-IV, and monitored over time with the longitudinal interval follow-up evaluation. @entity1314 were assessed with the diagnostic interview for DSM-IV-personality-disorders, and monitored over time with the follow-along-version. The occurrence and specific timing of @entity7027 were assessed with the life events assessment interview. Cox proportional-hazard-regression-analyses tested associations between time-varying levels of @entity7027 and @entity2613 relapse, controlling for comorbid @entity146 , @entity2613 duration, and time-varying @entity1314 status. RESULTS: @entity2613 relapse probability was 43%; @entity1279 and EDNOS did not differ in time to relapse. Negative @entity7027 significantly predicted @entity2613 relapse; elevated work and social stressors were significant predictors. Psychiatric comorbidity, @entity2613 duration, and time-varying @entity1314 status were not significant predictors. DISCUSSION: Higher work and social stress represent significant warning signs for triggering relapse for @entity1 with remitted @entity1279 and EDNOS.
