XXXX : a population-based study in Olmsted County, Minnesota.

@entity1 @entity15 @entity7995
We reviewed the records of all @entity1 with @entity7995 ( @entity7995 ) in Olmsted County, Minnesota, identified through the comprehensive records-linkage system at the Mayo Clinic, and identified 156 @entity7995 @entity1 from 1935 to 1991 who had onset of the disease while residing in Olmsted County (incidence cases). Poisson regression analysis revealed that age, gender, and calendar year were associated with incidence. The annual age- and sex-adjusted incidence rate was 5.1 per 100,000 @entity1 -years from 1985 to 1991. On December 1, 1991, 128 @entity1 with a documented history of @entity7995 resided in Olmsted County (prevalence cohort). The age- and sex-adjusted prevalence rate per 100,000 was 115. The average length of follow-up for the incidence cohort was 13.2 years. Life table analysis showed that 39% of the 95 @entity1 with isolated @entity7995 in the incidence cohort had progressed to clinically definite @entity15 ( @entity15 ) by 10 years of follow-up, that 49% had by 20 years, 54% by 30 years, and 60% by 40 years. There was no difference in the risk of developing @entity15 between @entity1 and @entity1 . The presence of venous sheathing (p = 0.044) and evidence for recurrent @entity7995 (p < 0.0001) were associated with an increased likelihood of developing @entity15 . The estimated 25-year survival rate was 88.3% +/- 5.8% for the incidence cohort with isolated @entity7995 , compared with 83.9% for the general US population of similar age and sex.
