High prevalence of @entity14 in @entity1 with XXXX .

@entity1 @entity652 @entity1560 @entity5 @entity75 @entity7936 @entity1442 @entity1561 @entity14 @entity2513 @entity1141
OBJECTIVE: @entity1561 ( @entity1561 ) affects 20-40% of the general adult population. Due to shared risk factors, it is postulated that @entity1561 @entity1 have an increased risk of @entity14 and should be a target group for screening. The aim of this study was to examine the prevalence of @entity14 in @entity1561 @entity1 and the risk of @entity14 in relation to the severity of @entity1561 histology. Design Cross-sectional study. SETTING: University hospital with case recruitment from the community and clinics. @entity1 : Subjects aged 40-70 years were recruited for colonoscopic screening from two study cohorts: (1) community subjects; and (2) consecutive @entity1 with biopsy proven @entity1561 . In the community cohort, hepatic fat was measured by proton-magnetic resonance spectroscopy. MAIN OUTCOME MEASURES: Prevalence of @entity2513 . @entity14 was defined as @entity5 or @entity652 with villous architecture or high grade @entity1141 . RESULTS: @entity1561 @entity1 (N=199) had a higher prevalence of @entity2513 (34.7% vs 21.5%; p=0.043) and @entity1442 (18.6% vs 5.5%; p=0.002) than healthy controls (N=181). Thirteen of 29 (45%) @entity1561 @entity1 with @entity1442 had @entity75 in the right sided colon. Among @entity1 with biopsy proven @entity1561 , @entity1 with @entity7936 (N=49) had a higher prevalence of @entity652 (51.0% vs 25.6%; p=0.005) and @entity1442 (34.7% vs 14.0%; p=0.011) than those with simple @entity1560 (N=86). After adjusting for demographic and metabolic factors, @entity7936 remained associated with @entity652 (adjusted OR 4.89, 95% CI 2.04 to 11.70) and @entity1442 (OR 5.34, 95% CI 1.92 to 14.84). In contrast, the prevalence of @entity652 and @entity1442 was similar between @entity1 with simple @entity1560 and control subjects. CONCLUSIONS: @entity7936 is associated with a high prevalence of @entity2513 and @entity1442 . The @entity652 are found more commonly in the right sided colon. @entity14 screening is strongly indicated in this high risk group.
