[Studies on the endocrinological metabolism of the parathyroid. II. Influence of XXXX on parathyroid function and @entity460 metabolism].

@entity1 @entity4545 @entity459 @entity5 @entity701 @entity460 @entity35 @entity1791 @entity461
@entity461 ( @entity461 ) is strongly concerned with the pathogenesis of urinary stones. @entity461 is mainly regulated by the serum @entity460 concentration and not by other hormones, as is usually the case. We studied whether @entity461 is also regulated by adrenocorticotrophic hormone ( @entity4545 ) or not. @entity4545 (0.25 mg) was injected intravenously to 17 @entity1 with @entity459 PHP, 7 @entity1 with @entity1791 , 7 @entity1 with @entity5 , and 6 control subjects. Serum @entity460 was significantly increased in only PHP. The serum @entity460 increase rate showed a significant positive correlation with serum alkaline phosphatase, and a negative correlation with the preinjected serum @entity460 . @entity461 was slightly increased in all four groups. Serum @entity701 and @entity4545 concentrations were not significantly different among the groups. @entity461 concentration in a culture medium of parathyroid tissues increased after @entity4545 addition. Serum @entity460 was significantly increased after @entity4545 injection in an adrenalectomized @entity35 , and decreased in a parathyroidectomized @entity35 . From our data and those of others, it appears that @entity4545 acts on the adrenal glands to decrease the serum @entity460 concentration, and might act directly on the parathyroid gland or bones to increase it.
