[Analysis of the present status of conservative therapy of XXXX ].

@entity1 @entity8 @entity1522 @entity8518 @entity177 @entity460 @entity1011
Treatment by dialyzing represents an important contribution to the therapy of @entity8518 @entity1 . On the other hand, besides high financial costs it is not possible to forger significant social and psychic consequences of this therapy. The present paper aimed at a pharmacoeconomic evaluation of the costs of conservative treatment of @entity8518 @entity1 . The secondary aim was to compare the costs of conservative treatment in @entity1 with markedly limited renal functions, @entity1011 clearance (Ccr < 0.4 ml/s), with those in @entity1 with only slightly and medium-reduced renal functions (Ccr 0.4-1 ml/s). Health documentation from three nephrological out- @entity1 surgeries was used to evaluate the results, the criterion for the selection of @entity1 being a nephrological diagnosis with Ccr below 1 ml/s. The group comprised 102 @entity1 aged 21-84 years (average age being 63.99 years), including 56 females (54.9%) and 46 males (45.1%). According to the stage of @entity8 , they were divided into two groups. The @entity1 with slightly and medium-reduced renal functions (Ccr 0.4-1.0 ml/s) represented nearly three quarters, whereas the @entity1 with markedly reduced renal functions (Ccr < 0.4 ml/s) only slightly more than one quarter. In the group under study, the pharmacotherapeutic costs represented 2,889,778.0 SK/year (28,331.16 SK/1 @entity1 /1 day), in @entity1 with @entity177 the costs being markedly higher (47,427.3 SK/1 @entity1 /1 day in comparison with 21,456.7 SK/1 @entity1 /1 day). Of total pharmacotherapeutic costs, 29.38% was represented by antihypertensive agents, 24.47% by preparations supplementing essential @entity1522 , 14.83% by hypolipidemic agents, 14.37% by preparations supplementing @entity460 , 6.19% by antianaemic agents, and 7.76% by other drugs. The results demonstrate that pharmacotherapy of @entity8 is costly but in comparison with elimination methods (dialysis) it is incomparably less expensive. The spectrum of employed agents is in agreement with the present-day trends in conservative treatment which decelerates the progress of @entity8 .
