Effect of a toothpaste containing XXXX , @entity4410 , and essential oils on gingival status in schoolchildren: A randomized clinical pilot study.

@entity1 @entity2413 @entity548 @entity14789 @entity4410 @entity1388
UNASSIGNED: Objective: This randomized double-blind in vivo pilot study has evaluated the effects of a toothpaste containing @entity1388 (control) versus toothpaste containing @entity1388 , @entity14789 , @entity4410 and essential oils (experimental) in controlling @entity2413 and @entity548 on probing in a sample of healthy schoolchildren. Method and Materials: In total, 48 @entity1 (8 to 10 years) were selected and randomly divided into two groups (experimental and control), using the two different toothpastes twice a day for 2 minutes each for a 4-week period. The investigation included an evaluation of plaque quantity, using the Turesky modified Quigley-Hein method, and @entity548 on probing that was recorded dichotomously. The unit of analysis was set at the gingival site level. Plaque Index and @entity548 on probing were analyzed using distribution tables and chi-square test. A generalized estimating equation was used to estimate the parameters of a generalized linear model with a possible unknown correlation between outcomes. Results: In total, 40 schoolchildren completed the trial. Considering each group separately, a statistically significant difference in plaque scores was recorded for both treatments (z-test = 9.23, P < .01 for the experimental toothpaste; and z-test = 7.47, P < .01 for the control toothpaste). Nevertheless, the effect over time was higher for the experimental toothpaste than for the control one (3.38 vs 1.96). No statistically significant results were observed regarding @entity548 on probing. Conclusion: The 4-week use of the experimental toothpaste seems to produce higher plaque reduction compared to fluoridated toothpaste without other antibacterial ingredients. This finding has to be confirmed in a larger study.
