Outcome of idiopathic XXXX . A 20 year experience.

@entity1 @entity230 @entity8 @entity1987 @entity229 @entity786 @entity3450 @entity177 @entity134 @entity1985
112 @entity1 with idiopathic @entity1985 have been referred from 1970 through 1989 at the Department of Pediatrics, University of Berne. One @entity1 remitted spontaneously without medication. Ninety-eight @entity1 responded to @entity229 : 15 had a single bout of @entity3450 , 47 developed a tendency towards relapses and 36 @entity134 dependence. In 28 @entity1 with tendency towards relapses cure took place on either @entity229 alone or @entity229 plus @entity786 . In 18 @entity1 with @entity134 dependency cure took place on @entity229 alone or @entity229 plus @entity786 . Thirteen @entity1 failed to respond to @entity230 . The course of the disease was more benign in 68 @entity1 with @entity1987 as compared with 14 @entity1 with focal and @entity8 . Immunofluorescence studies demonstrated mesangial IgM deposits in 14 out of 54 @entity1 , but this finding was not a marker for poor @entity134 response or progression to @entity177 . The course of the disease was especially unfavourable in @entity1 with persisting @entity3450 on completion of the initial course of @entity134 therapy. In conclusion it appears appropriate to define the disease in terms of @entity134 responsiveness as @entity134 resistant @entity1 sometimes show normal glomeruli, @entity134 responsive sometimes have focal and @entity8 or mesangial IgM deposits, and decisions depend more on the @entity134 responsiveness than on the histological features.
