@entity8277 expression in follicular and stromal compartments of the @entity1 ovary over the course of follicular growth, regression and XXXX .

@entity1 @entity1885 @entity2690 @entity8277 @entity1146
The cytologic localization and cellular levels of @entity2690 receptors in the @entity1 ovary during follicular growth, regression and @entity1146 were examined by the avidin/ @entity1885 immunoperoxidase techniques with a monoclonal antibody to @entity8277 . In primordial follicles, only the oocyte showed a weak immunostaining for @entity8277 , whereas the stromal cells surrounding primordial follicles were moderately immunostained. The earliest stage of follicular growth at which immunostaining for @entity8277 in granulosa cells and theca interna cells became apparent was the preantral stage. With the increase in the size of the follicles, the immunostaining of the oocyte and follicular elements intensified, whereas the staining intensity of the stromal cells surrounding growing follicles was reduced compared to those surrounding primordial follicles. The immunostaining in granulosa and theca interna cells persisted in the corpus luteum, and further intensified during the midluteal phase. In the regressing corpus luteum, the immunostaining was present only in the peripheral lutein cells adjacent to the central scar tissue. The corpus albicans was negative for the immunostaining, but the surrounding stromal cells exhibited predominant staining. In atretic follicles, the theca interna cells exhibited intense staining for @entity8277 without appreciable staining in the scattered granulosa cells, whereas the surrounding stromal cells were moderately immunostained. This is the first study to demonstrate notable changes in @entity8277 expression in the oocyte, granulosa cells, theca cells, lutein cells and surrounding stromal cells during follicular growth, regression and @entity1146 . The results obtained indicate @entity2690 participation in oocyte maturation, follicular growth and stromal cell function. The increased expression of @entity2690 receptors in theca interna cells of atretic follicles and in stromal cells surrounding the corpora albicans raises the intriguing possibility of @entity2690 involvement in the transformation of theca interna cells into stromal cells. This implies that @entity2690 may participate in remodelling ovarian local tissues following follicular @entity1146 and luteolysis in the @entity1 ovary.
