Is XXXX -dependent lipase concentration in serum of any help in @entity788 diagnosis?

@entity1 @entity3123 @entity788 @entity82 @entity5 @entity660 @entity409 @entity6741 @entity3619
The diagnostic value of @entity6741 -dependent lipase for @entity660 was tested in sera of 187 @entity1 . Of these @entity1 , 76 suffered from @entity3123 , 43 from nonmalignant @entity409 ( @entity82 and @entity3619 ), 18 from acute @entity788 , and 20 from chronic @entity788 . The remaining subjects were controls without pancreatic pathology. @entity6741 -dependent lipase was determined by a sandwich enzyme-linked immunosorbent assay using polyclonal antibodies. Amylase and CA 19-9 antigen were also determined. In sera from control @entity1 , the mean level of @entity6741 -dependent lipase was 1.5 micrograms/L. This level is quite similar to that of @entity1 with @entity409 (1.1 micrograms/L) and with chronic @entity788 (1.4 micrograms/L), but it was raised to 3.5 micrograms/L in @entity1 with acute @entity788 and decreased to 0.5 microgram/L in subjects with @entity788 . Thirty percent of control subjects and 73% of @entity5 @entity1 had a @entity6741 -dependent lipase serum level below the cutoff value of 0.5 microgram/L. In acute @entity788 , 11 of 16 subjects had levels above 1.5 micrograms/L. Amylase level largely increased in acute @entity788 but was normal in all other groups. Concerning CA 19-9 antigen, 65% of control @entity1 and > 80% of @entity1 with nonmalignant pancreatic or @entity409 had normal levels. In sera from @entity5 @entity1 , 80% presented with high levels. Accordingly, 36 of 38 @entity1 with @entity788 had either low serum levels of @entity6741 -dependent lipase (< 0.5 microgram/L) or high values of CA 19-9 antigen (> 37 U/ml; sensitivity 95%).(ABSTRACT TRUNCATED AT 250 WORDS)
