Serial stereotactic biopsies and CT scan in @entity11 : correlative study in 100 XXXX , oligo- @entity816 and oligodendrocytomas.

@entity3271 @entity5 @entity4 @entity11 @entity816 @entity2383
Histologic features of 100 supra-tentorial @entity816 , @entity3271 and oligo- @entity816 obtained from serial stereotactic biopsies were compared with the corresponding CT scans. Topographic comparisons provided by visualization of the biopsy trajectories on post-biopsy CT scans were available in 24 cases. Areas of contrast enhancement and low attenuation were compared with the histologic grade of @entity5 , @entity5 delimitation and structural type. The latter was determined as follows: @entity5 tissue without significant peripheral @entity5 cells; Type II-solid @entity5 tissue associated with peripheral @entity5 cells; Type III- @entity5 cells only. There was a strong correlation between areas of contrast enhancement and @entity5 microvascularity. In addition, contrast enhancement occurred only in the solid @entity5 tissue component of the @entity5 . This correlation accounted for the relationship observed between CT images and the structural type of @entity11 . Contrast enhancement was constant in structural @entity11 , @entity2383 , and @entity2383 . No correlation was found between @entity5 and contrast enhancement. Contrast enhancement occurred in all grades of @entity5 but was a constant feature of grade 4 @entity11 . The volume of the @entity5 could not be reliably determined from CT images alone. Areas of low attenuation on contrast CT scans could correspond to either @entity4 or to @entity4 parenchyma infiltrated by @entity5 cells. Serial stereotactic biopsies combined with calculations based on the CT scan provided a more precise definition of the @entity5 volume and identification of structural type. Such classification may prove useful in prospective analysis of various modes of therapy.
