Peripheral and autonomic nerve function in long-term @entity2690 -dependent XXXX .

@entity1 @entity4051 @entity6 @entity384 @entity2690 @entity1897 @entity19793
In a cross sectional study, motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV), beat-to-beat variation ( @entity19793 ) at rest and speed of @entity384 (SPD) have been investigated in 127 nonketonuric long-term @entity2690 -dependent @entity6 aged 19-72 yr and in age-matched control subjects. 84% of the @entity1 had electrophysiologic abnormalities, 58% had symptomatic @entity1897 , 35% had abnormal cardiac parasympathetic tests and 26% had abnormal pupillary tests. The most frequent pathologic feature was a decreased sural SNCV (66%). Among the @entity1 without symptomatic @entity1897 , 71% showed electrophysiologic abnormalities. MNCV and SNCV in median, peroneal and sural nerves correlated with @entity19793 (p less than 0.005), but only peroneal MNCV was related to SPD (p less than 0.005). There was also a relationship between @entity19793 and SPD (p less than 0.05). Glycosylated hemoglobin ( @entity4051 ) levels correlated inversely with median MNCV (p less than 0.001), and SNCV (p less than 0.03), peroneal MNCV (p less than 0.05) and sural SNCV (p less than 0.05). @entity1 with abnormal peripheral or autonomic nerve function tests or symptomatic @entity1897 had significantly higher @entity4051 levels than those with normal tests (p less than 0.04) or asymptomatic @entity1 (p less than 0.01). Median MNCV and SNCV, sural SNCV and @entity19793 deteriorated with age (p less than 0.05) and median SNCV and peroneal MNCV deteriorated with the duration of @entity6 (p less than 0.001). Our findings show an association between @entity1897 in long-term @entity2690 -dependent @entity6 .(ABSTRACT TRUNCATED AT 250 WORDS)
