Short-term reproducibility of ambulatory blood pressure monitoring in XXXX .

@entity1 @entity11559 @entity8 @entity101 @entity1556
BACKGROUND AND OBJECTIVES: Nondipping, defined as a less than 10% decline in Night:Day (N:D) ratio of blood pressure using 24 h ambulatory blood pressure monitoring, is associated with poor cardiovascular outcomes. However, its reproducibility has been questioned in @entity8 . MATERIALS AND METHODS: Twenty-five of 29 recruited @entity101 or @entity1556 @entity1 with @entity8 completed ambulatory blood pressure monitoring on two occasions, 7-15 days apart, on a stable antihypertensive regimen. Daytime and night-time were defined as 6:00-21:59 h and 22:00-5:59 h, respectively. Correlation and concordance coefficients for systolic blood pressure (SBP), diastolic blood pressure ( @entity11559 ), and heart rate were determined based on N:D and Asleep:Awake (A:A) ratios. Consistency of dipping was assessed by using Cohen's Kappa statistics. RESULTS: Mean (  standard deviation) for age, estimated glomerular filtration rate, differences in daytime and night-time SBP and @entity11559 were 43.12 years (8.55 years), 63.1 ml/min (20.5 ml/min), 11.74 mmHg (8.2 mmHg), and 10.82 mmHg (6.4 mmHg), respectively. Seventeen of 25 (68%) and 18 of 25 (72%) @entity1 maintained the same dipping category based on D:N or A:A separation. Cohen's Kappa was 0.34 for D:N ratio and 0.38 for A:A ratio. Correlation and concordance coefficients were 0.89 and 0.88 for daytime SBP, 0.91 and 0.91 for daytime @entity11559 , 0.79 and 0.78 for night-time SBP, 0.81 and 0.80 for night-time @entity11559 , 0.58 and 0.56 for N:D ratio of SBP, and 0.56 and 0.53 for N:D ratio of @entity11559 . Coefficients for A:A ratio were almost identical to N:D values except for A:A ratios of SBP (0.69 and 0.67) and @entity11559 (0.48 and 0.45). CONCLUSION: Repeated measures of SBP and @entity11559 , 7-15 days apart, are highly correlative and concordant in the studied population, but nondipping, even though predominant, was found to be modestly reproducible.
