Treatment of hyperlipidemia in XXXX .

@entity1 @entity1007 @entity301 @entity453 @entity165
OBJECTIVE: To assess the evidence that lipid lowering prevents @entity301 ( @entity301 ) events in @entity1 . DATA SOURCES: English-language literature assessing the effects of @entity165 lowering with dietary and/or drug interventions as primary or secondary prevention on @entity301 events in @entity1 . MAIN OUTCOME MEASURES: @entity301 and total mortality were the primary outcomes assessed. Angiographic regression of @entity453 was a secondary outcome. STUDY SELECTION, DATA EXTRACTION, AND DATA SYNTHESIS: All nine of the identified studies that met the criteria were included. Relative risks for @entity301 and total mortality were calculated from available data. Summary relative risks were calculated using meta-analytic techniques. CONCLUSIONS: There is no evidence from primary prevention trials that @entity165 lowering affects total mortality in healthy @entity1 , although the available data are limited. Limited evidence suggests that treatment of @entity1007 in @entity1 with @entity301 may decrease @entity301 mortality. Future research should address the role of dietary and other nondrug treatment of @entity1007 in @entity1 at high risk for @entity301 .
