Chronic stimulation of the globus pallidus internus for control of XXXX .

@entity3519 @entity1 @entity3520
Our experience of deep brain stimulation of the globus pallidus internus (GPi-DBS) for @entity3519 is summarized. A total of 5 @entity1 with @entity3520 underwent GPi-DBS. There were 3 males and 2 females. The age at onset of @entity3519 ranged from 8 to 45 years and the age at surgery for GPi-DBS ranged from 17 to 59 years. Two of the @entity1 had been treated previously by bilateral thalamotomy or unilateral pallidotomy at other clinics and then developed new symptoms or recurrence. All were stimulated bilaterally. No surgical complications were encountered. The symptoms of @entity3519 were scored by the Burke-Fahn-Marsden @entity3519 rating scale (BFMDRS). The scores ranged from 18 to 62 before surgery. An improvement in the symptoms of @entity3519 was observed soon after the initiation of GPi-DBS, and additional progressive improvement was noted during a period of months or even years after surgery. The score at 6 months after surgery reached a level ranging from 4 to 23. The improvement in score ranged from -51% to -92%. GPi-DBS produced a marked effect even in @entity1 who had previously undergone thalamotomy or pallidotomy. At 6 months after surgery, all @entity1 were receiving bipolar stimulation with a wide interpolar distance, using contact 0 or 1 as the cathode and contact 2 or 3 as the anode. Stimulation was being performed at an intensity of around 2.0 V with a pulse width of 0.21 ms at a high frequency ranging from 120 to 140 Hz. GPi-DBS represents an important therapeutic option in many @entity1 with @entity3520 .
