Correlation between the AHCPR (Agency For Health Care Policy and Research) risk stratification and angiographic morphology in non-ST-segment elevation XXXX .

@entity1 @entity1187 @entity715 @entity301
OBJECTIVES: Risk stratification in acute coronary syndromes is an important diagnostic tool guiding future therapy. We evaluated the correlation between the AHCPR (Agency for Health Care Policy and Research) risk classification and angiographic morphology in @entity1 with non-ST-segment elevation @entity1187 (NSTE-ACS). STUDY DESIGN: A total of 163 @entity1 hospitalized with the diagnosis of NSTE-ACS were prospectively enrolled. All the @entity1 underwent AHCPR risk analysis followed by coronary angiography. Based on the AHCPR system, the @entity1 were classified as low (n=25, mean age 55  10 years), intermediate (n=55, mean age 58  10 years), and high (n=83, mean age 61  11 years) risk groups. RESULTS: The three groups were similar with regard to gender, age, and @entity301 risk factors (p>0.05). Comparison of the high-risk group with intermediate+low-risk group with regard to lesion morphology showed significantly higher rates of complex lesions (31.9% vs. 4.0%, p=0.001), total occlusion (23.2% vs. 0%, p=0.001), and intracoronary @entity715 (13% vs. 2%, p=0.02) in the high-risk group. In univariate analysis, high risk was significantly associated with the presence of complex lesion, total occlusion, intracoronary @entity715 , and TIMI flow <III. Of these, only the presence of complex lesion (p=0.005) and TIMI flow <III (p=0.02) were associated with high risk in multivariate analyses. CONCLUSION: Our findings show that the incidence of high-risk coronary morphology is increased in NSTE-ACS @entity1 having a high-risk profile according to the AHCPR classification.
