@entity1204 : I. A clinicopathologic study of clear-cell carcinoma and XXXX .

@entity1204 @entity1 @entity5 @entity189 @entity3 @entity204
In a pathologic review of 1224 cases of @entity1204 , 1023 were confirmed cases of @entity1204 . Fifty-six (5.5%) were clear-cell adenocarcinoma (CCE). Fifteen cases of " @entity189 " ( @entity189 ) were examined for comparison. Fifty-five @entity1 with CCE and all with @entity189 were followed for at least five years or until @entity204 . There were only 19 survivors among those with CCE. No five-year survivor subsequently died of disease. Of the 15 @entity1 with @entity189 , 13 survived for five years although two additional @entity1 died of recurrent disease at 5.4 and seven years. All survivors of CCE were Stage I @entity1 at the time of diagnosis. All were postmenopausal, and had a median age of 67 years compared with 58 years for @entity1 with @entity189 . Unlike @entity189 , the morphology of CCE was preserved in the subsequent hysterectomy specimen, in the recurrent disease, and in the @entity3 . CCE was proportionately more common in black @entity1 and the five-year survival was 12.5% as compared with 39.1% for white @entity1 . In contrast to @entity1204 in general, most @entity1 who failed treatment died of disease. There was no increase in the relative frequency over the 23-year time period of the study. Age at time of diagnosis seemed to be an important prognosticator. Prognosis also correlated well with stage of disease and depth of @entity3 . It correlated to a somewhat lesser extent with the method of treatment and had a poor correlation with the histologic pattern or degree of cellular differentiation: however, essentially all @entity5 were considered to be poorly differentiated. Finally, a histologic tissue marker in the form of hyalin-like, PAS-positive, diastase-resistant bodies was found in the 64% of the @entity1 with CCE.
