Motion VEPs, stereopsis, and bifoveal fusion in XXXX with strabismus.

@entity1 @entity5971 @entity751
PURPOSE: The link between nasal-temporal motion asymmetries and anomalous binocular sensory function in infantile @entity5971 ( @entity5971 ) has led to the idea that visual evoked potential responses to horizontal motion (mVE) is an alternative measure of sensory binocularity to stereopsis. A second hypothesis is that the mVEP response is a marker for bifoveal fusion. The purpose of this study was to directly evaluate these two hypotheses by examining the correspondence between the mVEP response and both stereoacuity and bifoveal fusion in a cohort of strabismic @entity1 with variable binocular sensory function. METHODS: Motion VEPs, random dot stereopsis, and bifoveal fusion were measured in 94 @entity1 : 20 with infantile @entity5971 , 16 with infantile accommodative @entity5971 , 22 with late-onset accommodative @entity5971 , 10 with intermittent infantile strabismus, and 26 normal control @entity1 . RESULTS: @entity1 with infantile @entity5971 and infantile accommodative @entity5971 had high concordance between mVEP responses and stereoacuity and mVEP responses and bifoveal fusion. Asymmetric mVEP responses were highly concordant with both no measurable stereopsis and an absence of fusional vergence. @entity1 with late-onset accommodative @entity5971 and intermittent infantile strabismus revealed discordance between the mVEP response and stereoacuity and high concordance between the mVEP response and bifoveal fusion. Asymmetric mVEP responses were highly concordant with the absence of bifoveal fusion and the minimum-size prism to elicit fusional vergence. CONCLUSIONS: The qualitative and quantitative relationship between the mVEP response and fusional vergence suggests that the mVEP response is an objective measure of bifoveal fusion. The availability of such a test will facilitate studies of normal development of bifoveal fusion and development of @entity751 in strabismus.
