The value of HLA phenotypes in the prognosis of XXXX .

@entity1 @entity978
The study included 52 @entity1 with @entity978 , 32 males and 20 females, whose ages ranged from 3 to 36 years (34 under and 18 over 15 years). All @entity1 were carefully staged, and lymph-node biopsies were taken for histopathological examination. HLA phenotype determinations were carried out, and the frequencies were statistically compared with those of normal Egyptian controls. We followed the @entity1 for 3 years to monitor the effect of therapy. In order to determine the prognostic value of @entity1 ' characteristics (age, stage, histologic pattern and HLA phenotypes), statistical analysis and retrospective stratification studies were performed. The frequency of HLA-AI was significantly increased in our @entity1 . The relative risk showed that @entity1 carrying the AI antigen are 6 times more susceptible than those lacking it. There was no significant difference in the frequency of AI antigen in relation to the histopathologic subtypes. Furthermore, the results revealed a prognostic value of the HLA marker. In conclusion, we suggest that chemotherapy should be added to radiotherapy of marker-positive @entity1 at any stage.
