The preoperative study of mediastinal lymph nodes metastasis in XXXX by endoscopic ultrasonography (EUS) and helical computed tomography (CT).

@entity1 @entity1149 @entity2
OBJECTIVE: Accurate staging of mediastinal lymph nodes in @entity1 with @entity2 is fundamental for their treatment and prognosis. The aim of this study was to compare the value of EUS and CT staging in @entity1 with @entity1149 ( @entity1149 ) with postsurgical stage. METHODS: Ninety two @entity1 with @entity1149 underwent EUS and CT for preoperative detection of metastases to the mediastinal lymph nodes. EUS examinations were done with the ultrasonic linear array scanning echoendoscope (FG 32 UA, Hitachi/Pentax), CT-Toshiba Exvision GX scanner, with 24-s spiral acquisition, pitch 1:1 (7 mm collimation, 4 mm reconstruction index), during i.v. administration of non-ionic iodinated contrast media. RESULTS: The frequency of mediastinal involvement was 22.7%. The regions most accessible by EUS evaluation were subaortic, subcarinal and paraoesophageal lymph nodes. On a per- @entity1 basis, EUS and CT results were: sensitivity 70.0 and 60.0%, specificity 80.6 and 72.6%, accuracy 77.2 and 68.5%. On a per-sites basis, the sensitivity of EUS evaluation was 78.8%, specificity 89.9%, accuracy 87.7%, comparing with CT-63.6, 84.0, 79.9%, respectively. When the EUS and CT images were analysed in combination, the sensitivity increased to 86.4%. CONCLUSION: We believe that EUS and CT should be used together for preoperative non-invasive staging of mediastinal lymph nodes in @entity1 with @entity1149 .
