Prenatal exposure of a @entity1 with XXXX to 'horsetail' ( @entity26360 ) herbal remedy and alcohol: a case report.

@entity1 @entity15248 @entity137 @entity353 @entity28598 @entity2438 @entity245 @entity9138 @entity26360 @entity72 @entity74 @entity1068
INTRODUCTION: @entity2438 is a @entity245 in which the interactions of genetic, epigenetic and environmental influences are thought to play a causal role. In @entity1 , throughout embryonic and fetal life, brain development is exquisitely susceptible to injury caused by exposure to toxic chemicals present in the environment. Although the use of herbal supplements during pregnancy is relatively common, little information is available on their association with fetal neurodevelopment. This is, to the best of our knowledge, the first report in the literature to associate a new plausible mechanism of @entity137 with a case of @entity72 through a @entity15248 potentiated by concomitant use of herbal supplements and @entity1068 exposure. CASE PRESENTATION: We describe the pediatric environmental history of a three-year-old Caucasian @entity1 with an @entity72 . We utilized her pediatric environmental history to evaluate constitutional, genetic, and environmental factors pertinent to manifestation of @entity74 . Both parents reported prenatal exposure to several risk factors of interest. A year prior to conception the mother began a @entity353 diet and ingested 1200 mg/day of 'horsetail' ( @entity26360 ) herbal remedies containing thiaminase, an enzyme that with long-term use can lead to @entity15248 . The mother reported a significant @entity353 during the pregnancy and a @entity28598 . @entity9138 ( @entity9138 ) deficiency could have been potentiated by the horsetail's thiaminase activity and @entity1068 exposure during pregnancy. No other risk factors were identified. CONCLUSIONS: A detailed and careful pediatric environmental history, which includes daily intake, herbal remedies and @entity1068 exposure, should be obtained from all @entity1 with @entity72 . Maternal consumption of @entity1068 and of herbal supplements with suspected or potential @entity137 should be avoided during pregnancy. The prospective parents should perform preconception planning before pregnancy.
