Effect of XXXX on clinical events after percutaneous coronary intervention.

@entity1 @entity2120 @entity548
OBJECTIVE: To explore the influence of @entity2120 on clinical events after percutaneous coronary intervention (PCI). METHODS: We recruited 400 @entity1 that had undergone the percutaneous coronary intervention without complications in the Cardiology Department of Changhai Hospital consecutively from May 2011 to December 2012. The @entity1 were randomly assigned to receive anticoagulation therapy ( @entity2120 ) or no anticoagulant. @entity1 were assessed for major adverse cardiac and cerebrovascular events (MACCEs) during hospitalization and at 1 and 12 months after PCI. RESULTS: There were no significant differences in the frequency of MACCEs between the two groups during hospitalization, at 1 month or 12 months post-PCI. During hospitalization, MACCEs occurred in 1.5% of the anticoagulation group versus 1.6% of the non-anticoagulation group (P>0.9). The groups had comparable rates of major @entity548 (3.6% vs 2.1%, P=0.37), but minor @entity548 was increased in the anticoagulation group (29.1% vs. 18.7%, P=0.016). At 1 month post-PCI, MACCEs occurred in 1.5% of the anticoagulation group and 2.6% of the non-anticoagulation group, (P=0.5), and at 12 months post-PCI, the rates were 5.6% vs. 6.2%, respectively (P=0.8). CONCLUSIONS: The frequency of MACCEs after PCI in the non-anticoagulation group was not significantly increased compared with that of the anticoagulation group. However, the rate of minor @entity548 during hospitalization is significantly lower in non-anticoagulation group than that in anticoagulation group. The results suggest that routine anticoagulation therapy after PCI is not necessary for @entity1 without procedure complications.
