[Relation of serum @entity1243 and XXXX to cardiovascular risk factors in older adults: a Guangzhou biobank cohort study-CVD].

@entity1 @entity1243 @entity1254 @entity412 @entity413 @entity165
OBJECTIVE: To study the serum @entity1243 and @entity1254 levels among relatively healthy older @entity1 and their association with traditional cardiovascular risk factors. METHODS: Personal medical history and blood sample were collected from 1515 older @entity1 of Guangzhou. Fasting serum @entity413 , lipids, @entity1243 and @entity1254 were measured. RESULTS: (1) In relatively healthy older adults aged 50 or above, from Guangzhou, the following data were seen: serum @entity1243 levels (x(-)    s) in @entity1 and @entity1 were (3.90    2.36) ng/ml and (12.17    2.01) ng/ml respectively; serum @entity1254 levels in @entity1 and @entity1 were (5.33    2.78) mg/L and (7.18    2.58) mg/L respectively. (2) Serum @entity1243 and @entity1254 level increased with age. After adjusting for body mass index, the trend for serum @entity1243 level in @entity1 (P < 0.001) and @entity1254 level in @entity1 (P < 0.05) were significantly associated with age. (3) No association was found between cigarette smoking and levels of @entity1243 or @entity1254 in both @entity1 and @entity1 after adjusting for age (P from 0.09 to 0.76). (4) In both @entity1 and women, serum @entity1243 and @entity1254 levels were positively associated with waist circumference/body mass index, systolic blood pressure, low-density lipoprotein @entity165 and @entity412 (P from 0.04 to < 0.001). In @entity1 , @entity1243 was also significantly associated with the increase of diastolic blood pressure and @entity413 but decreased with high-density lipoprotein @entity165 (P from 0.03 to 0.02). (5) Decreased @entity1254 level was associated with increased waist circumference and @entity412 in both @entity1 and @entity1 (P from 0.003 to < 0.001) and with the increased body mass index, fasting plasma @entity413 as well as with decreased high-density lipoprotein @entity165 in @entity1 (P from 0.05 to < 0.001) but with increased systolic blood pressure and total @entity165 in @entity1 (P from 0.05 to 0.006). CONCLUSION: In Guangzhou city, among relatively healthy older adults aged 50 or above, their serum @entity1243 and @entity1254 levels were lower in @entity1 than in women. Serum @entity1243 level in @entity1 and @entity1254 level in @entity1 were significantly associated with the increase of age. Increased @entity1243 and decreased @entity1254 levels were associated with increased traditional cardiovascular risk factors.
