Serial changes of elevated serum IgG4 levels in IgG4-related XXXX .

@entity1 @entity788 @entity10972 @entity991 @entity262 @entity1126 @entity5441 @entity4611 @entity134 @entity9353 @entity2403
OBJECTIVE: @entity788 ( @entity788 ) and @entity9353 have recently been recognized as pancreatic or salivary gland lesions of IgG4-related @entity262 . These are frequently associated with elevated serum IgG4 levels. This study aimed to clarify clinical implications of serial changes of elevated serum IgG4 levels in IgG4-related @entity262 . METHODS: Serial changes of elevated serum IgG4 levels were examined in patients with IgG4-related @entity262 . @entity1 Serial changes of elevated serum IgG4 levels were examined in 44 @entity1 : @entity788 (n=24), @entity9353 (n=8), @entity788 (n=5), @entity1126 (n=1), @entity991 (n=1), @entity5441 (n=1), @entity10972 (n=1), @entity4611 (n=1), idiopathic @entity788 (n=1), and @entity2403 (n=1). RESULTS: The serum IgG4 levels decreased in all @entity1 with @entity788 and @entity9353 after @entity134 therapy. The serum IgG4 levels were normalized in 46% of @entity788 @entity1 and 38% of @entity9353 patients. The serum IgG4 levels were not normalized at remission in 3 of 4 relapsed @entity788 @entity1 , and re-elevation of serum IgG4 levels was detected in all relapsed patients. Elevated serum IgG4 levels decreased in 3 @entity1 with @entity788 after resection or chemotherapy, and decreased in @entity1 with @entity5441 , @entity991 , and @entity4611 after @entity134 therapy. CONCLUSION: Measurement of serial serum IgG4 levels is useful to determine the disease activity of IgG4-related @entity262 .
