Does XXXX conform to a distinctive pattern in obstructive sleep apnea syndrome?

@entity1 @entity303 @entity73 @entity1030 @entity409 @entity27 @entity195
@entity27 ( @entity27 ) is a recognized cause of @entity73 . By using a cross-sectional comparative study, we aimed to verify whether neuropsychological performance of untreated @entity27 @entity1 conforms to a distinctive pattern. Forty-nine newly diagnosed, untreated @entity27 @entity1 , 27 with @entity303 ( @entity303 ), 31 with mild to moderate @entity303 of @entity195 (DAT) and 63 with severe @entity1030 ( @entity1030 ), all free from major comorbid dementing conditions were chosen for the study. The groups were matched for age and education. We found a bimodal distribution of cognitive performance in @entity27 group, which was therefore divided into two clusters having better (OSAb, n = 35) and worse (OSAw, n = 14) performance on a battery of 10 cognitive indexes. Cognitive performances of OSAb, OSAw, @entity303 , DAT and @entity1030 were compared by discriminant analysis. OSAb performed better than OSAw in all but one test. Deductive thinking and verbal attainment were more severely impaired in OSAw than in @entity1030 @entity1 . Constructive ability, deductive thinking and both verbal attainment and immediate memory were comparably impaired in OSAw and DAT. The mean neuropsychological scores of OSAw and @entity303 were comparable, but 71% of OSAw @entity1 had a distinctive cognitive profile, i.e. a group specific pattern of @entity73 , according to discriminant analysis. One of four newly diagnosed @entity27 @entity1 had a severe and distinctive @entity409 mainly involving inductive and deductive thinking, and constructive ability. Some analogy with cognitive pattern of @entity303 suggests that a mainly subcortical damage underlies this dysfunction.
