XXXX causes brain plasticity: a functional MRI study.

@entity1 @entity130 @entity1347 @entity409 @entity397 @entity85 @entity8638 @entity942
BACKGROUND: The mechanoreceptors located in anterior cruciate ligament (ACL) constitute an afferent source of information toward the central nervous system. It has been proposed that @entity1347 causes a disturbance in neuromuscular control, affects central programs and consequently the motor response resulting in serious @entity409 of the injured limb. PURPOSE: The objective of this study was to investigate whether @entity8638 causes plastic changes in brain activation patterns. STUDY DESIGN: Case control study; Level of evidence, 3. METHODS: Seventeen right leg-dominant male @entity1 with @entity1347 and 18 matched healthy male @entity1 with no special sport or habitual physical activity participated in this study. @entity1 selection criteria comprised a complete right unilateral anterior cruciate @entity397 > or = 6 months before testing. Brain activation was examined by using functional magnetic resonance imaging technique (1.5-T scanner). RESULTS: Results show that @entity1 with anterior cruciate @entity942 had diminished activation in several sensorimotor cortical areas and increased activation in 3 areas compared with controls: presupplementary motor area, posterior secondary somatosensory area, and posterior inferior temporal gyrus. CONCLUSION: The current study reveals that anterior cruciate @entity942 can cause reorganization of the central nervous system, suggesting that such an injury might be regarded as a neurophysiologic @entity409 , not a simple peripheral @entity85 . This evidence could explain clinical symptoms that accompany this @entity130 and lead to severe @entity409 . Understanding the pattern of brain activation after a peripheral @entity130 such as @entity130 lead to new standards in rehabilitation and motor control learning with a wide application in a number of clinical and research areas (eg, surgical procedures, @entity1 re-education, athletic training, etc).
