A biography of XXXX and medicine in Hong Kong and China.

@entity1 @entity4447 @entity2799 @entity137 @entity1778 @entity4801 @entity3494
@entity4447 has been used in traditional Chinese medicine for over 5000 years, but lost its appeal due to its @entity137 . It was rediscovered in western medicine and enjoyed a renaissance from 1830 to 1930, as the first effective chemotherapy against syphilis, @entity4801 and @entity1778 . These years were also a time of political turmoil in China. The Nanking treaty (29 August 1842) turned Hong Kong into a colony, while the Xinhai Revolution (10 October 1911) gave birth to a republic of China. @entity3494 returned to China and Hong Kong with the establishment of the first medical schools from 1887 to 1920. Until 1950, oral @entity4447 was the standard anti-leukaemic treatment in Queen Mary Hospital. The advent of alkylating chemotherapeutic agents replaced @entity4447 in Hong Kong and around the world. In the 1970s, however, the specific activity of @entity4447 against @entity2799 was re-discovered during the Cultural Revolution in Harbin, China. In 1997, Hong Kong was returned to China. In the same year, @entity4447 returned to the world stage. Intravenous @entity4447 became the worldwide standard therapy for relapsed @entity2799 . Oral administration of @entity4447 was revived in Hong Kong in 2000. This resulted in the first locally produced, registered, patented prescription drug in Hong Kong. Pending imminent manufacture, this product is poised to revolutionise @entity2799 care and may hold the key to saving the lives of @entity2799 @entity1 worldwide. The remarkable journey of @entity3494 in the setting of medical history of China and Hong Kong is reviewed.
