XXXX in the elderly.

@entity1 @entity644 @entity8 @entity1494 @entity904 @entity1011 @entity811 @entity4434
OBJECTIVE: To investigate the glomerular and proximal tubular renal function and the prevalence of @entity1494 in the elderly. DESIGN: Cross-sectional study. SETTING: General community in the city of S  o Paulo. @entity1 : A population-based sample of 200 elderly subjects was randomly selected. Of these, 81 subjects (45 females and 36 males; mean +/- SD age: 73.7 +/- 6 years) accepted to undergo laboratory examination and were included in the study. MAIN OUTCOME MEASURES: 24-h @entity1011 clearance (CCr), microalbuminuria, urinary @entity904 -binding protein (urRBP), leukocyturia, @entity811 and total @entity644 . RESULTS: CCr was lower than 80 ml/min/1.73 m2 in 68% of the subjects. The median (range) CCr was 65 ml/min/1.73 m2 (21-112) in males and 77 ml/min/1.73 m2 (27-107) in females (p = 0.14). No individual had serum @entity1011 greater than 1.5 mg/dl. urRBP determination was normal in 79 of 81 subjects. The prevalence of microalbuminuria (> 20 micrograms/ml) was 31% (n = 25, 19 @entity1 and 6 @entity1 ). These individuals presented higher mean systolic blood pressure (147 +/- 20 vs. 135 +/- 22 mmHg, p = 0.02) and mean serum @entity1011 (1.13 +/- 0.20 vs. 0.96 +/- 0.20 mg/dl, p < 0.01) than those without microalbuminuria. The prevalence of leukocyturia (> 10,000/mm3), @entity811 (> 10,000/mm3) and total @entity644 (> or = 0.3 mg/dl) was 19%, 28% and 5% in males and 33%, 27% and 4% in females. CONCLUSIONS: @entity8 and @entity1494 are frequent features in the elderly, however, proximal @entity4434 is uncommon in this population.
