Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With XXXX .

@entity1 @entity3458 @entity158
BACKGROUND: Vaso-occlusive @entity158 , the hallmark of @entity3458 ( @entity3458 ), is a major contributor to morbidity, poor health-related quality of life, and health care utilization associated with this disease. There is wide variation in the burden, frequency, and severity of @entity158 experienced by @entity1 with @entity3458 . As compared with health care utilization for @entity158 , a daily @entity158 diary captures the breadth of the @entity158 experience and is a superior measure of @entity158 burden and its impact on @entity1 . @entity158 diaries based on real-time data capture methods overcome methodological barriers and limitations of paper @entity158 diaries, but their psychometric properties have not been formally established in @entity1 with @entity3458 . OBJECTIVES: To develop and establish the content validity of a web-based multidimensional @entity158 diary for adolescents and young adults with @entity3458 and conduct an end-user review to refine the prototype. MATERIALS AND METHODS: Following identification of items, a conceptual model was developed. Interviews with adolescents and young adults with @entity3458 were conducted. Subsequently, end-user review with use of the electronic @entity158 was conducted. RESULTS: Two iterative cycles of in-depth cognitive interviews in adolescents and young adults with @entity3458 informed the design and guided the addition, removal, and modification of items in the multidimensional @entity158 diary. Potential end-users provided positive feedback on the design and prototype of the electronic diary. CONCLUSION: A multidimensional web-based electronic @entity158 diary for adolescents and young adults with @entity3458 has been developed and content validity and initial end-user reviews have been completed.
