Segmental arterial mediolysis: a precursor to XXXX ?

@entity1 @entity455 @entity527 @entity1593 @entity548 @entity1347 @entity3468 @entity4267 @entity1410 @entity439 @entity490 @entity2553
We describe five cases of @entity1347 ( @entity1347 ), formerly known as segmental mediolytic @entity3468 . @entity1347 occurs in epicardial coronary arteries and in the abdominal splanchnic arteries. @entity1 with abdominal @entity1347 are generally elderly, whereas coronary @entity1347 presents in neonates, @entity1 , and young adults. @entity1347 is initiated by mediolysis of the outer media, which can expand to involve the mid- and inner media. Accompanying alterations include @entity527 at the medial adventitial junction and replacement of the lysed muscle fibers by fibrin, erythrocytes, and granulation tissue. Transmural mediolysis results in arterial wall gaps frequently complicated by dissecting @entity1410 and @entity439 . @entity548 stem from these complications. @entity1347 involving abdominal splanchnic arteries clinically presents with @entity490 and distension, falling hematocrit, and shock. Simultaneous involvement of more than one abdominal artery is frequent, and branches of the @entity1593 are most commonly affected. Various disease states that provoke pathologic stimuli for endothelial mediated vasoconstriction occur in the immediate clinical background of @entity1 with @entity1347 . Certain morphologic features of @entity1347 suggest that this @entity455 is due to @entity2553 , which we putatively ascribe to focal endothelial paracrine dysfunction. Organization of uncomplicated @entity1347 lesions could resemble certain types of @entity4267 , suggesting that the genesis of such arterial lesions is related to @entity2553 .
