XXXX transmitted by laser-generated plume (aerosol).

@entity1 @entity5 @entity1800 @entity544 @entity291
OBJECTIVE: To evaluate the possibility of disease transmission through liberated plume from virally infected tissue that is exposed to the @entity544 laser. DESIGN: @entity291 papillomavirus-induced cutaneous fibropapillomas were exposed to the @entity544 laser. Laser settings were within the range of clinically used settings. The laser plume (aerosol) was suctioned and collected and then reinoculated onto the skin of @entity291 . SETTING: University laboratory research center. MAIN OUTCOME MEASURES: Laser plume viral content and postinoculation @entity5 growth were analyzed and documented. RESULTS: Collected laser plume contained papillomavirus DNA in all tested laser settings. The viral DNA was most likely encapsulated. Tumors developed at laser plume-inoculated sites for all laser parameter settings. Histological and biochemical analyses revealed that these @entity5 were infected with the same virus type as present in the laser plume. CONCLUSIONS: Laser plume has been shown, for the first time to our knowledge, to actually transmit disease. Strict care must be maintained by the laser practitioner to minimize potential health risks, especially when treating @entity1800 or @entity1 with @entity1800 .
