Urinary Incontinence and XXXX After Robotic Versus Open Radical Prostatectomy: A Prospective, Controlled, Nonrandomised Trial.

@entity1 @entity263 @entity323 @entity322
BACKGROUND: Robot-assisted laparoscopic radical prostatectomy (RALP) has become widely used without high-grade evidence of superiority regarding long-term clinical outcomes compared with open retropubic radical prostatectomy (RRP), the gold standard. OBJECTIVE: To compare @entity1 -reported @entity322 and @entity323 12 mo after RALP or RRP. DESIGN, SETTING, AND @entity1 : This was a prospective, controlled, nonrandomised trial of @entity1 undergoing prostatectomy in 14 centres using RALP or RRP. Clinical-record forms and validated @entity1 questionnaires at baseline and 12 mo after surgery were collected. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSES: Odds ratios (ORs) were calculated with logistic regression and adjusted for possible confounders. The primary end point was @entity322 (change of pad less than once in 24h vs one time or more per 24h) at 12 mo. Secondary end points were @entity323 at 12 mo and positive surgical margins. RESULTS AND LIMITATIONS: Of 2625 eligible @entity1 , 2431 (93%) could be evaluated for the primary end point. At 12 mo after RALP, 366 @entity1 (21.3%) were incontinent, as were 144 (20.2%) after RRP. The adjusted OR was 1.08 (95% confidence interval [CI], 0.87-1.34). @entity323 was observed in 1200 @entity1 (70.4%) 12 mo after RALP and 531 (74.7%) after RRP. The adjusted OR was 0.81 (95% CI, 0.66-0.98). The frequency of positive surgical margins did not differ significantly between groups: 21.8% in the RALP group and 20.9% in the RRP group (adjusted OR: 1.09; 95% CI, 0.87-1.35). The nonrandomised design is a limitation. CONCLUSIONS: In a Swedish setting, RALP for @entity263 was modestly beneficial in preserving erectile function compared with RRP, without a statistically significant difference regarding @entity322 or surgical margins. @entity1 SUMMARY: We compared @entity1 -reported @entity322 after prostatectomy with two types of surgical technique. There was no statistically significant improvement in the rate of urinary leakage, but there was a small improvement regarding erectile function after robot-assisted operation.
