Outcomes and prognostic factors of primary XXXX following complete surgical resection: a single surgeon experience.

@entity5 @entity1 @entity356 @entity2467
OBJECTIVE: To examine the surgical outcomes and to identify prognostic factors influencing @entity5 recurrence and survival after curative resection of primary @entity356 as performed by one surgeon. MATERIAL AND METHOD: The medical records of @entity1 with primary @entity356 ( @entity2467 or @entity2467 -positive) who underwent curative resection by one surgeon between January 2001 and March 2009. The clinicopathological features, @entity5 recurrence, and recurrence-free survival were assessed. RESULTS: Twenty-two @entity1 (10 males and 12females) with a median age of 66 years (range, 39-98 yrs) were reviewed. According to the NIH risk criteria, high-risk, intermediate-risk and low-risk GISTs were found in 12 (54.5%), one (4.5%), and nine (41%) @entity1 , respectively. After a median follow-up of 42 months (range, 19-96 months), three @entity1 (13.6%) developed @entity5 recurrence, all of whom had high-risk GIST. No @entity1 died during this follow-up period The recurrence-free probability at 5 years was 88% (95% CI; 59%-97%). Univariable analysis showed that high mitotic count (> 5/50 HPF) was a significant predictor of @entity5 recurrence. CONCLUSION: Low and intermediate-risk @entity356 have an excellent prognosis after complete surgical resection alone, while high-risk group are associated with increased disease recurrence despite complete surgical resection. Adjuvant therapy should be advocated for @entity1 with high-risk gastric GISTs. High mitotic count is an important prognostic factor for recurrence after surgery.
