Injection of diethylstilbestrol on the first day of incubation affects morphology of sex glands and reproductive behavior of XXXX .

@entity5872 @entity4336 @entity4743
@entity5872 eggs were injected with @entity4743 (0.9-1,000 micrograms) dissolved in 50-microliter of @entity4336 oil on day 1 of incubation. Higher doses of @entity4743 (250-1,000 micrograms) reduced hatchability to 37-33% compared to 61% for @entity4336 oil-injected controls. Lower doses of @entity4743 (0.9-125 micrograms) had no effects on hatchability. In a second study, eggs were injected with 0.9 or 1.9 micrograms of @entity4743 and the survivors were assessed up to 12 weeks posthatch. @entity4743 did not affect hatchability, but did increase mortality during the first 4 weeks posthatch. Females were affected more than males. At 10 days of age, open-field activity of some birds was examined. The acquisition and reversal of a visual discrimination task was studied at 6 weeks of age. @entity4743 had no effect on these measurements. Ten females from each group were chosen randomly to determine egg production over a single 28-day period beginning at 6 weeks of age. Exposure to @entity4743 blocked egg production in these birds. The oviduct weights of 12-week-old females were decreased by 50%, but ovarian weights were not affected. Testicular weights were not affected. In a third study reproductive behaviors and social-dominance behaviors of males were markedly attenuated in birds exposed to 0.48 or 1.9 micrograms @entity4743 in ovo.
