Optical coherence tomography assessment of retinal nerve fiber layer thickness changes after XXXX surgery.

@entity1 @entity227 @entity231 @entity726 @entity2790
PURPOSE: To assess changes in retinal nerve fiber layer (NFL) thickness in @entity726 @entity1 after filtration surgery by using optical coherence tomography (OCT). DESIGN: Retrospective observational case series. @entity1 : Thirty-eight eyes of 31 @entity726 @entity1 who underwent trabeculectomy or a combined procedure of @entity231 extraction and trabeculectomy were evaluated retrospectively. METHODS: Eyes were imaged with OCT before surgery (1 week to 6 months before surgery; mean +/- standard deviation [SD], 71.3 +/- 61.2 days) and after surgery (6-12 months after surgery; 247.2 +/- 63.5 days) to measure peripapillary NFL thickness. MAIN OUTCOME MEASURES: Changes in mean and segmental NFL thickness with respect to age, postoperative change in @entity2790 ( @entity2790 ), preoperative @entity227 . RESULTS: A significant increase in the overall mean NFL thickness was present after surgery (P < 0.0001). Segmental analysis found a significant increase in NFL thickness in the nasal, superior, and temporal quadrants. @entity2790 decreased after surgery from 22.0 +/- 6.4 mmHg to 11.4 +/- 4.7 mmHg (mean +/- SD). Twenty-eight (73.7%) of 38 eyes had an @entity2790 >30%. The mean NFL thickness increase (0.5- microm/mmHg decrease of @entity2790 ) was significantly correlated with the @entity2790 (r = -0.41; P = 0.03). No correlation was found between NFL thickness changes and age, preoperative @entity227 . CONCLUSIONS: A significant increase of the mean NFL thickness, which was related to @entity2790 , was detected after @entity726 filtration surgery.
