Normal values of quantitative T2' in a spontaneously @entity101 XXXX prone @entity35 stem at 3T.

@entity1 @entity64 @entity101 @entity63 @entity35
INTRODUCTION: Regarding therapy and prognosis of acute @entity63 @entity64 the identification of @entity63 penumbra is pivotal. A promising candidate is BOLD-imaging using qT2'-maps. For valid interpretation of experimental studies in animals normal values for qT2' are needed. Normal values in @entity1 at 1.5T already exist. Normal values for cortical and subcortical structures in a spontaneously @entity101 @entity64 prone @entity35 stem (SHR-SP) at a fieldstrength of 3T are reported. MATERIALS AND METHODS: 39 (20 males and 19 females) spontaneously @entity101 @entity64 prone (SHRSP) @entity35 were examined in a 3T scanner using a dedicated small animal coil. Mean weight was 144.1    8.2g and mean age was 60.2    2.7 days. For the calculation of qT2' multiple echo T2w and T2 w images were acquired. ROIs were placed into deep and cortical grey matter in five different brain regions to obtain values for qT2', qT2 and qT2. RESULTS: Mean qT2' for cortical grey matter was 74.76    33.27 ms and 67.73    17.86 ms for deep grey matter. The 99% confidence interval for cortical grey matter was 69.91-79.61 ms. For qT2 it was 79.02    2.9 ms and 70.45    1.89 ms, respectively. For qT2 it was 34.65    5.25 ms and 31.9    2.9 ms. CONCLUSION: The values for qT2' presented here can serve as reference values for further studies examining the @entity63 penumbra in a @entity35 model.
