Lung transplantation for XXXX --a single center experience over 8 years.

@entity1 @entity4095 @entity6 @entity26 @entity281 @entity358 @entity3147 @entity1779 @entity4154 @entity204 @entity1577
OBJECTIVE: Colonization of the lung and mediastinal lymph nodes with multi-resistant bacteria, @entity6 and @entity3147 represent potential risk factors for lung transplantation in @entity1577 . We therefore reviewed our experience in this @entity1 population. METHODS: Between December 1988 and March 1997, 219 lung and heart-lung transplantations were performed at our institution. Of these, 39 procedures were done in 35 @entity1 with @entity1577 . All candidates (mean age 26 years) were @entity26 dependent (preoperative mean @entity4095 : 44.8 +/- 9.1 Torr, preoperative mean PCO2: 53.4 +/- 10.5 Torr, one @entity1 on respirator). Of the primary operations, 34 were performed as bilateral sequential lung transplants, one as a heart-lung transplantation. RESULTS: Mean duration on respirator for survivors was 3.1 (1-12) days, mean ICU and hospital stay were 4.7 (1-13) and 28 (12-79) days, respectively. The 3-month mortality rate was 5.7% (two @entity1 died due to acute graft failure on days 36 and 73). Other causes of @entity204 in the follow-up were @entity1779 (one @entity1 ) and chronic graft failure (three @entity1 ). The survival rates were 91% at 1 year, 83% at 3 years and 76% at 5 years. In eight @entity1 , a @entity4154 ( @entity4154 ) developed (in four cases grade 3). The freedom of @entity4154 (grade 1 or more) at 1, 3 and 5 years was 87, 79 and 55%, respectively. Four retransplantations were performed. Of the 29 @entity1 alive, only seven are physically limited. CONCLUSION: Bilateral lung transplantation for @entity1577 allows for acceptable early- and long-term results. Postoperative survival is not impaired by @entity281 , @entity6 and @entity3147 . Long-term functional outcome seems to be comparable to lung transplantation in @entity1 without @entity358 .
