Intraoperative XXXX Assay during Minimally Invasive Parathyroidectomy May Be Helpful in the Detection of Double @entity652 and May Minimise the Risk of Recurrent Surgery.

@entity1 @entity459 @entity3 @entity3243 @entity652 @entity461
Background. @entity3 ( @entity3 ) is increasingly replacing the traditional bilateral neck exploration in the treatment of @entity459 ( @entity459 ). Intraoperative @entity461 (IOPTH) measurement has recently been introduced as a useful adjunct in confirming successful excision of abnormal parathyroid gland. Aims. We evaluate the safety, efficacy, and clinical usefulness of IOPTH measurement during @entity3 in a district general hospital. Methods. Retrospective review of eleven consecutive @entity1 with @entity459 who underwent @entity3 with IOPTH, following preoperative assessment with ultrasound and sestamibi scans. Results. All @entity1 had successful removal of the abnormal parathyroid gland. The concordance rate between ultrasound and sestamibi scan in localising the @entity3243 was 82%. IOPTH measurement confirmed the removal of @entity652 in all cases and, in one case, led to identification of a second @entity652 , not localised preoperatively. The median hospital stay was 2 days (range 1-7 days). All @entity1 remained normocalcaemic after a median of 6 months (range 1-10 months). Conclusions. @entity3 is a feasible, safe, and effective method for treatment of @entity459 . The use of IOPTH monitoring potentially offers increased sensitivity in detecting multiglandular disease, can minimise the need and risk associated with recurrent operations, and may facilitate cost-effective minimally invasive surgery.
