Presentation and treatment of uterine XXXX in adolescence: a systematic review.

@entity1 @entity417 @entity5 @entity490 @entity2909
UNASSIGNED: BackgroundUterine @entity2909 is the most common gynecological @entity5 in the reproductive years. However, it is extremely rare in adolescence (<1%), with few reports found in the literature. The biological behavior of such @entity5 in this age group is unknown, as well as the best possible treatment for this population. We aimed to analyze all available reports of uterine @entity2909 in adolescence.MethodsA systematic review was performed at PubMed/MEDLINE and EMBASE. Between 1965 and 2014, 19 reports were found on uterine @entity2909 in @entity1 under 18  years. The following parameters were discussed: age, @entity5 diameter, symptoms, clinical treatments, surgical treatments, hemodynamic changes.ResultsMean age was 15.35 (14  17) years. Mean @entity5 diameter was 12.28  cm (3  30) and median diameter was 10  cm. Most @entity1 presented with symptoms (87.5%), including abnormal uterine bleeding (10/18) and @entity490 (6/18). A pelvic mass was the most common finding. Two @entity1 required transfusion due to @entity417 . One @entity1 underwent abdominal hysterectomy, and the others underwent myomectomy. Mean follow-up was 1  year and 8  months, and only case recurred, after 6  months.ConclusionLeiomyomas   biologic behavior in adolescents may be different from that of older @entity1 , but their molecular characteristics still haven  t been analyzed. Optimal treatment is still not defined, but myomectomy has several advantages in this population. @entity2909 must be remembered as an important differential diagnosis of pelvic mass in adolescents.
