ANALYSIS OF CHANGES IN CHARACTERISTICS OF SEVERE RETINOPATHY OF PREMATURITY XXXX AFTER SCREENING GUIDELINES WERE ISSUED IN CHINA.

@entity1 @entity1713 @entity989
PURPOSE: To describe the changes in the characteristics of @entity1 treated for severe @entity989 ( @entity989 ) in a tertiary referral unit in China after screening guidelines were issued in 2004 and to evaluate the effectiveness of the current criteria. METHODS: Information on consecutive @entity1 referred to a single eye department for treatment of Stage 3 (Type 1 pretheshold and threshold disease), Stage 4, and Stage 5 @entity989 between January 2001 and May 2012 was retrieved from medical records. RESULTS: The mean gestational age was 29.98    2.13 weeks (range 26-34 weeks), and the mean birth weight was 1,414.32    343.18 g (range 742-2,087 g). The proportion of @entity1 with Stage 4 and Stage 5 @entity989 decreased statistically significantly over time (P = 0.026 and P < 0.001, respectively) after screening guidelines for @entity989 were issued in 2004. The median postmenstrual age when @entity1 first visited the study hospital was 48.32 weeks (range 30-602 weeks); later presentation was significantly associated with more advanced @entity989 (P < 0.001). In addition, the postmenstrual age of first presentation showed a significant decrease over time (P < 0.001) after the screening guidelines were issued. The current Chinese screening guidelines cover 99.63% of @entity1 while 9.07% of @entity1 exceeded the U.K. screening criteria and 35.77% of @entity1 exceeded the U.S. criteria. CONCLUSION: After the government issued guidelines on @entity989 screening, the birth weight and gestational age of severe @entity989 @entity1 remain similar. Big @entity1 got severe @entity989 as before. But the awareness of @entity989 increased, the proportion of @entity1 with @entity1713 caused by @entity989 decreased, and the @entity1 received more timely treatment. The current @entity989 screening criteria are very effective.
