XXXX Outbreak in Isiro, Democratic Republic of the Congo, 2012: Signs and Symptoms, Management and Outcomes.

@entity1 @entity1944 @entity390 @entity2598 @entity548 @entity294 @entity391 @entity448 @entity1395 @entity166 @entity158 @entity4841 @entity311 @entity71133 @entity925 @entity221
UNASSIGNED: Data collected during the 2012 @entity2598 ( @entity2598 ) epidemic in the Democratic Republic of the Congo were analysed for clinical signs, symptoms and case fatality of @entity2598 caused by @entity71133 ( @entity71133 ), establishment of differential diagnoses, description of medical treatment and evaluation of the quality of clinical documentation. In a quantitative observational prospective study, global epidemiological data from 52 @entity1 (34 @entity1 within the community, 18 @entity1 treated in the Ebola Treatment Centre) were entered anonymously into a database, subsequently matched and analysed. Relevant findings include an over-representation of females among community @entity2598 cases (85.3%) and of community @entity2598 cases in the age group of 15-54 years (82.4%). All ETC @entity1 had @entity221 (55.6% of all 18 ETC @entity1 during their hospital stay) or self-reported @entity221 (88.2% upon admission) at some point of time during their illness. Major symptoms of ETC @entity1 during hospital stay included @entity1395 (82.4%), @entity448 (82.4%), @entity925 (70.6%), sore throat/difficulty swallowing (70.6%), @entity4841 (76.5%) and @entity390 (70.6%). Gastrointestinal signs and symptoms ( @entity390 , @entity294 , @entity391 ) (76.4%) as well as general @entity158 (94.1%) were frequent in ETC @entity1 . The median duration of @entity2598 was 18 days, while the mean incubation period was 11.3 days. Differential diagnosis of @entity2598 included @entity311 (28.3%), @entity1944 (10.9%), and @entity166 (10.9%). There was also an important variation in clinical evolvement. Quality of documentation was adversely affected by the way @entity1 file contents were transferred from inside to outside the high-risk zone, entailing a mean mismatch value of 27.3% between @entity1 file contents inside vs. outside the high-risk zone. This study adds further description of @entity2598 (frequently non-specific signs and symptoms, non frequent @entity548 , a long incubation period, long duration of disease) and emphasizes the need for improving clinical monitoring and documentation in @entity2598 outbreak settings.
