Diagnostic value of ultrasonography in @entity1 with palpable mammographically noncalcified XXXX .

@entity1 @entity854 @entity5 @entity0
PURPOSE: To analyze the diagnostic accuracy of mammography, ultrasonography (US), and both methods combined in evaluation of palpable noncalcified @entity0 . MATERIAL AND METHODS: Mammograms and sonograms of 200 @entity1 with palpable noncalcified breast masses were retrospectively analyzed independently by four experienced radiologists in 3 sessions: Mammography or US interpretations in the first two and combined reading in the last session. @entity854 and mammographically obvious @entity5 were excluded. Receiver operating characteristic (ROC) analyses were performed for 115 (60 benign and 55 malignant) @entity5 and subgroups according to tissue density and @entity5 size. A single ROC curve for each diagnostic test was obtained by pooling the individual ratings. The area under the ROC curve was used as a measure of diagnostic performance. RESULTS: US revealed significantly higher diagnostic performance than mammography for @entity5 larger than 2 cm. Combined reading showed significantly higher performance than mammography except for @entity5 smaller than 2 cm. The performance of all three tests was reduced in dense parenchyma, and significantly so for mammographic and combined interpretation. CONCLUSION: The accuracy of US in @entity1 with palpable mammographically noncalcified and not obviously malignant @entity0 is lower than reported for mixed sample populations. The accuracy of US may be influenced by breast parenchyma density. Combined reading offers the highest diagnostic accuracy.
