Standardized uptake value and apparent diffusion coefficient of XXXX evaluated with integrated whole-body PET/MR: Correlation with pathological prognostic factors.

@entity1204 @entity1 @entity5 @entity3
PURPOSE: To evaluate the correlation between maximum standardized uptake value (SUVmax ) and minimum apparent diffusion coefficient (ADCmin ) of @entity1204 derived from an integrated positron emission tomography / magnetic resonance (PET/MR) system and to determine their correlation with pathological prognostic factors. MATERIALS AND METHODS: This prospective study was approved by the Institutional Review Board of the hospital, and informed consent was obtained. Between April and December 2014, 47 consecutive @entity1 with @entity1204 were enrolled and underwent simultaneous PET/MR examinations before surgery. Thirty-six @entity1 with measurable @entity5 on PET/MR were included for image analysis. Pearson's correlation coefficient was used to evaluate the correlation between SUVmax and ADCmin of the @entity5 . The Mann-Whitney U-test was utilized to evaluate relationships between these two imaging biomarkers and pathological prognostic factors. RESULTS: The mean SUVmax and ADCmin were 14.7        7.1 and 0.48        0.13 * 10(-3) mm(2) /s, respectively. A significant inverse correlation was found between SUVmax and ADCmin (r   =   -0.53; P   =   0.001). SUVmax was significantly higher in @entity5 with advanced stage, deep @entity3 , cervical invasion, lymphovascular space involvement, and lymph node @entity3 (P   <   0.05). ADCmin was lower in @entity5 with higher grade, advanced stage, and cervical invasion (P   <   0.05). The ratio of SUVmax to ADCmin was higher in @entity5 with higher grade, advanced stage, deep @entity3 , cervical invasion, lymphovascular space involvement, and lymph node @entity3 (P   <   0.05). CONCLUSION: SUVmax and ADCmin of @entity1204 derived from integrated PET/MR are inversely correlated and are associated with pathological prognostic factors.
