XXXX : Clinical and ultrastructural features of a new family.

@entity1 @entity1711 @entity14968 @entity1710 @entity74 @entity29883 @entity8032
Objective: This article describes the diagnosis, clinical and microscopic (histopathology and ultrastructural) features and treatment of a new family with @entity29883 ( @entity29883 ) and highlights the importance of this @entity74 . Study Design: To characterize the pattern of inheritance and the clinical features, members of a new family with @entity29883 were examined. The pedigree was reliably constructed including the four latest generations of family. @entity1710 and @entity1711 staining and ultrastructural analysis were performed with the gingival tissue. Results: Examination of the family pedigree revealed that the @entity1 III-2 represent the index @entity1 of this family (initial @entity1 with a mutation), which was transmitted to her daughter through an autosomal dominant mode of inheritance. The affected @entity1 showed a generalized @entity8032 . The @entity1 was treated with surgical procedures of gingivectomy and gingivoplasty. The diagnosis was confirmed by histopathology examination that showed a well-structured epithelium with @entity14968 inserted in fibrous connective tissue with increased amount of collagen. The ultrastructural aspects of the tissue show collagen fibrils exhibiting their typically repeating banding pattern with some fibrils displaying loops at their end. Moreover, it was possible to seen in some regions fibrillar component presenting tortuous aspects and loss of the alignment among them. Conclusions: This @entity29883 frequently resulted in both esthetic and functional problems. The genetic pattern of this Brazilian family suggested a new mutation, which was later transmitted by an autosomal dominant trait.
