Double-blind, randomized, controlled trial of local anesthetic use for iliac crest donor site XXXX .

@entity1 @entity11375 @entity1341 @entity1286 @entity158
Autogenous iliac crest bone grafts are often used for @entity1 undergoing @entity11375 ( @entity11375 ). Study findings have shown that @entity158 at the iliac crest donor site can often be more severe than that at the primary operation site. A method used to eliminate @entity158 after bone harvesting involves infiltration of a local anesthetic directly into the site. This study examined the efficacy of local anesthetic infiltration in the control of donor site @entity158 , utilizing a randomized, double-blind, placebo-conrolled design. All @entity1 received standard postoperative intravenous and oral analgesic. Those in the study group also received six injections of @entity1341 0.25% into the donor site, while @entity1 in the placebo group received normal saline injections. @entity1 receiving @entity1341 (n = 14) consistently reported lower @entity158 scores than @entity1 receiving the placebo (n = 8), with significant differences noted 3 hours after the first and second doses of the study drug. The @entity1341 group's mean @entity1286 intake for the first 24 hours after surgery was found to be lower (32 mg; placebo 44 mg), whereas @entity1 younger than 49 years who received @entity1341 were found, on average, to have stayed in the hospital one day less (3.6 days) than placebo group @entity1 (4.5 days). Younger @entity1 receiving @entity1341 required less @entity1286 and had, on average, a reduced length of stay. The clinical implication of using local anesthetic for the relief of donor site @entity158 suggests that it is a safe and efficacious technique.
