Expression of @entity986 protein and XXXX in periampullary @entity189 .

@entity1 @entity3123 @entity1124 @entity986 @entity5 @entity189 @entity4910 @entity2269 @entity3 @entity5436
OBJECTIVE: The majority of the @entity5 in periampullary region are @entity3123 . The aim of this study was to compare histopathological features of ampulla of @entity189 with @entity1124 and to determine diagnostic and predictive values of @entity986 protein and @entity4910 expression. MATERIAL AND METHOD: Tissue samples from @entity1124 were obtained from 31 @entity1 who underwent pancreticoduodenectomy for @entity189 . The study group was composed of 12 @entity1 and 19 @entity1 . Their median age was found to be 62.32 years (range 26-85 years). The parameters analyzed in the study included lymph node @entity3 , perineural invasion, differentiation, duodenal invasion, grade of @entity5436 and @entity986 and @entity4910 expression in tumoral and peritumoral pancreatic tissues. RESULTS: In both @entity5 groups, the loss of @entity986 protein expression was significantly correlated with perineural invasion (p = 0.0001). Perineural invasion was more frequent in the @entity1124 group than the ampulla of @entity189 group (p = 0.01). When desmoplasia and lymphoplasmacytic stromal infiltration were examined, desmoplastic reaction was significantly higher in @entity1124 than ampulla of @entity189 (p = 0.01). No significant difference was observed between @entity5 groups for @entity4910 (p > 0.05). CONCLUSION: The results suggest that loss of @entity986 protein expression may be a sign for poor prognosis in @entity5 that is correlated mainly with perineural invasion. @entity2269 stromal reaction may be a distinctive feature for @entity1124 compared with ampulla of @entity189 .
