Prescription trajectories and effect of total hip arthroplasty on the use of analgesics, hypnotics, antidepressants, and anxiolytics: results from a population of total hip arthroplasty XXXX .

@entity1 @entity308 @entity148 @entity572 @entity158 @entity1118
UNASSIGNED: @entity572 ( @entity572 ) has been shown to reduce @entity158 and improve function. In addition, it is suggested that @entity572 improves sleep and alleviates symptoms of @entity148 and @entity308 . @entity1 with @entity1118 are frequent users of analgesic and psychotropic drugs and thereby risk adverse drug events. The impact of @entity572 on such drug use has not been thoroughly investigated. Based on merged data from the Norwegian Prescription Database and the Norwegian Arthroplasty Register, this study sought to investigate redeemed medications in a complete population (N = 39,688) undergoing @entity572 in 2005 to 2011. User rates and redeemed drug volume of analgesics (nonsteroid anti-inflammatory drugs (NSAIDs), opioids, and nonopioids) and psychotropics (hypnotics, anxiolytics, and antidepressants) were calculated for 4 quarters before and 4 quarters after surgery. We analysed preoperative prescription trends (Q1 vs Q4), postoperative prescription (Q4 vs Q5), and long-term effect of surgery (Q4 vs Q8). Before surgery, use of all drug groups increased from Q1 to Q4. Use of opioids, nonopioids, and hypnotics dramatically increased from Q4 to Q5. Long-term (Q4 vs Q8) surgery reduced prescriptions of analgesics, hypnotics, and anxiolytics, but not antidepressants. Overall, the present results extend the positive effects of @entity572 to include reduced reliance on medication to alleviate symptoms.
