Relationship of contractile function to transmural extent of @entity1188 in XXXX with chronic @entity453 .

@entity1 @entity583 @entity66 @entity1188 @entity453
OBJECTIVES: We sought to determine the relationship of contractile function to the transmural extent of @entity1188 (TEI) in @entity1 with chronic @entity453 . BACKGROUND: In the setting of reperfused, chronic @entity583 ( @entity583 ), the relationship of contractile function to the TEI has not been established. METHODS: We studied function by cine magnetic resonance imaging (MRI) and the TEI by contrast-enhanced MRI in 31 @entity1 with @entity66 162 +/- 62 days after reperfused first @entity583 . RESULTS: Of all 516 segments with @entity583 , blinded observers were unable to detect abnormal thickening in 193 (37%), and wall thickening measured quantitatively in these segments was 66 +/- 28%. Of the 193 segments, 163 (84%) were @entity1188 limited to the subendocardium. The average TEI reached 53% before half of the @entity1 had abnormal contractile function. When @entity1 with small @entity583 (< or =5% of total left ventricular [LV] mass) were excluded, the average TEI reached 43% before half the @entity1 had abnormal function. In subjects with small @entity583 (< or =5% of total LV mass [n = 13]), even segments with TEI >75% had normal function (14 of 14) because they were surrounded by normally moving neighbor segments. CONCLUSIONS: In the setting of reperfused chronic @entity583 , the TEI approaches 50% before contractile dysfunction can be systematically identified. Contractile function cannot be used to rule out chronic @entity583 .
