MRI Features of XXXX That Predict Favorable Clinicopathologic Outcomes.

@entity1 @entity1358 @entity5 @entity3
OBJECTIVE: The purpose of this article is to determine whether MRI features of @entity1358 ( @entity1358 ), such as enhancing solid component and T1 signal intensity, are associated with clinicopathologic outcomes. MATERIALS AND METHODS: This retrospective study included 241 RCCs in 230 @entity1 who underwent preoperative MRI, had pathologic analysis results available, and were monitored for at least 3 months. A radiologist assessed @entity5 features on MRI, including unenhanced T1 signal relative to renal cortex and the percentage of solid enhancing components. The electronic medical record or follow-up images were reviewed to assess for the development of local recurrence or @entity3 . Statistical analysis was performed to correlate imaging features at MRI with pathologic and clinical outcome. RESULTS: The following @entity5 features were observed: predominantly cystic morphologic features (defined as solid component  <= 25%, n = 33), solid component greater than 25% (n = 208), T1 hypointensity (n = 97), and T1 intermediate intensity or hyperintensity (n = 144). Local recurrence or @entity3 were observed in 14 @entity1 . Compared with T1-intermediate or -hyperintense lesions, T1-hypointense RCCs were more likely to be low stage (90.7% vs 74.3%; p = 0.001) and low grade (78.9% vs 41.8%; p < 0.001) and had a lower rate of recurrence or @entity3 (3.3% vs 8%; p = 0.167). Compared with lesions with greater than 25% solid enhancement, predominantly cystic RCCs were more likely to be lower stage (93.9% vs 78.8%; p = 0.053) and lower grade (94.7 vs 56.5%; p < 0.001) and to have no incidence of recurrence or @entity3 (0% vs 6.9%; p = 0.227). RCCs that were both cystic and T1 hypointense (n = 14) were lower stage (100% vs 79.6%; p = 0.047) and lower grade (92.9% vs 58.1%; p = 0.01) and had no recurrence or @entity3 on follow-up. CONCLUSION: Cystic and T1-hypointense @entity1358 show less-aggressive pathologic features and favorable clinical behavior.
