Incidence and Outcomes of XXXX After Orthotopic Cardiac Transplant: A Population-Based Cohort.

@entity1 @entity8 @entity101 @entity260 @entity810
OBJECTIVES: @entity810 is a frequent complication after orthotopic cardiac transplant. We aimed to describe the risk factors for @entity810 after cardiac transplant according to @entity8 : Improving Global Outcomes criteria. MATERIALS AND METHODS: We retrospectively studied a population-based cohort of cardiac transplant recipients (aged > 12 y) at Ba  kent University between February 2003 and January 2015. Of 94 @entity1 , 64 were evaluated and included in the study. The main outcome was @entity810 , defined and classified according to @entity8 : Improving Global Outcomes criteria, during 7 postoperative days. Other outcomes included risk factors, use of renal replacement therapy, @entity260 , mortality, and kidney recovery. RESULTS: Mean age at transplant was 34.14    16.30 years, and 45 @entity1 (70.32%) were @entity1 . @entity810 developed in 34 (53.12%) of 64 cardiac transplant recipients, with severity classified as stage 1 in 10 (15.62%), stage 2 in 14 (21.87%), and stage 3 in 10 (15.62%). Renal replacement therapy was given to 25 @entity1 (39.06%). @entity1 with @entity810 were significantly older (40.41    15.85 y vs 27.03    13.91 y; P = .001), had larger body surface area (1.78    0.28 m2 vs 1.61    0.31 m2; P = .033), and more frequently had a history of @entity101 (P = .011) and smoking (P = .007) than did @entity1 without @entity810 . They also had lower intraoperative urine output (453.380    266.85 mL) than did @entity1 who did not develop @entity810 (632.33    430.94 mL (P = .01). CONCLUSIONS: According to the @entity8 : Improving Global Outcomes criteria, @entity810 occurs in more than 50% of heart transplant @entity1 postoperatively. Older age, larger body surface area, and history of @entity101 and smoking are associated with acute @entity8 following orthotopic heart transplant.
