[The nature of immunohistochemically defined astrocytic cells in XXXX @entity11 ].

@entity21078 @entity330 @entity5 @entity1184 @entity11 @entity331 @entity40 @entity35 @entity7229
The nature of astrocytic cells in @entity35 @entity11 induced by @entity330 ( @entity331 ) was studied by means of immunohistochemically demonstrating @entity40 ( @entity40 ), @entity7229 and beta-subunit of S 100 protein ( @entity21078 ) on paraffin sections. A special attention was paid to elucidating whether astrocytic cells would be neoplastic or not. The astrocytic cells in @entity5 were compared with astrocytes in normal @entity35 brains and reactive astrocytes around a stab wound for their morphology, distribution and immunohistochemical characteristics. @entity40 positive astrocytic cells in @entity5 were roughly divided into astrocytic cells and @entity1184 cells that showed morphologically similar appearance to fibrous astrocytes and @entity1184 reactive astrocytes around a stab wound respectively. A few multi-nucleated pleomorphic cells regarded as a kind of @entity1184 cells were also noted in gross @entity5 . @entity40 positive cells were diffusely distributed in early neoplastic proliferations and microtumors, while in gross @entity5 they tended to be localized at the periphery. The @entity40 positive cells were scattered among negative cells of @entity5 , forming no @entity5 mass. These findings suggest that the @entity40 positive cells show no @entity5 , even though histopathologically they exhibit atypism or pleomorphism. The quantitative analysis of @entity40 positive cells in @entity5 indicated more than 8% in most @entity5 in the white matter, whereas less than 8% in @entity5 in the gray matter and approximately 5% in gross @entity5 . The predominance of @entity40 positive cells in the white matter was also observed in lesions induced by a stab wound.(ABSTRACT TRUNCATED AT 250 WORDS)
