Reproductive physiology and behavior in the male XXXX following acute and chronic peripheral adrenergic depletion by @entity2997 .

@entity2997 @entity251 @entity308 @entity146 @entity2754 @entity35
The effect of @entity2997 , an adrenergic neuron blocking agent, on @entity146 , penile reflexes, and spontaneous seminal emission (SSE) in the @entity35 was studied by acute (i.e., 4 hours prior to testing) and daily IP injection of a low (5 mg/kg) and moderately high (25 mg/kg) dose of the drug. Acute low dose treatment eliminated the expulsion of a seminal plug with behavioral ejaculation without affecting @entity146 ; while acute high dose administration significantly decreased the number of intromissions preceding ejaculation and eliminated emission in copula and SSE for 3 days, with no evidence of @entity2754 . Acute high dose treatment also increased the number of long flips displayed in the penile reflex test, and resulted in significant @entity308 in plasma @entity251 (T) and luteinizing hormone (LH) levels. Daily injection with the low dose eliminated emission in and ex copula for 4 weeks, without altering @entity146 or penile reflexes. Seminal emission in copula reappeared more rapidly after stopping injections than SSE. Chronic high dose treatment was also without effect on copulatory activity. There was a partial recovery of emission in copula by the fourth week of treatment, suggesting that a nonadrenergic mechanism had assumed this function. In penile reflex tests conducted after 4 and 8 weeks, significantly fewer erections were displayed by drug-treated animals. During the period of initial recovery of emission in copula, emission during the reflex test was markedly increased, but SSE was decreased. Plasma T was significantly suppressed after two and four weeks of daily injections, but not thereafter, while plasma LH levels were not affected by the drug.
