Lifetime cost of @entity7135 in France: Scenarios of severe @entity693 and septicemia with XXXX .

@entity1 @entity18536 @entity740 @entity693 @entity2319 @entity302 @entity7135
UNASSIGNED: @entity7135 ( @entity7135 ) is life-threatening and can result in severe sequelae. In France, no data have been published on the costs of severe @entity7135 cases. Two realistic scenarios were developed with national experts (clinicians and social workers): a 6-year-old @entity1 with @entity18536 with amputation of both legs below the knee (case A) and a 3-year-old with @entity693 and severe neurological sequelae (case B). Additional scenarios included other typical sequelae of @entity7135 such as @entity740 ( @entity740 ), profound @entity2319 and @entity302 . Data on healthcare, disability, educational and other resource use were obtained from experts and families of @entity1 with similar sequelae. Unit costs (2013) were mainly obtained from the literature and the National Health Insurance (NHI). Time horizon was based on life expectancies of @entity1 (77 and 55 years, respectively). A 4% discount rate decreasing to 2% after 30 years was applied. Costs are presented from the perspective of the NHI, publicly funded organizations and @entity1 ' families or their private health insurances. @entity18536 with amputations is associated with a lifelong discounted cost of    768,875. Adding @entity740 doubles the amount (   1,480,545). @entity693 with severe neuro-cognitive sequelae results in a lifelong discounted cost of    1,924,475. Adding profound @entity2319 and @entity302 slightly increases the total cost (   2,267,251). The first year is the most expensive in both scenarios (   166,890 and    160,647 respectively). The main cost drivers for each scenario are prostheses and @entity1 /adult stays in healthcare facilities, respectively. Overall, @entity1 ' families or his private insurance had to pay around 13% of total cost (101,833    and 258,817   , respectively). This study fills a gap in the body of knowledge on @entity7135 sequelae care and lifetime costs in France. The potentially high economic burden of @entity7135 , in addition to its physical, psychological and social burden, reinforces the need for prevention.
