Complications and fetal outcome in XXXX pregnancy. Intensified conventional versus insulin pump therapy.

@entity1 @entity3152 @entity6 @entity3465 @entity5835 @entity1592 @entity1468 @entity73200
From 1978 to 1986 a total of 189 pregnant @entity6 @entity1 gave birth at our hospital. In this randomized prospective study the influence of @entity6 treatment in normoglycemic @entity1 , continuous subcutaneous insulin infusion (n = 48) versus intensified conventional treatment (n = 41), is evaluated. These two groups of @entity1 are further compared to @entity1 (n = 28) who underwent conventional @entity6 treatment during pregnancy. It can be shown from our data that the rate of complications such as @entity1468 , @entity1592 , @entity3152 and @entity3465 can be reduced by intensified conventional and insulin pump treatment as compared to conventionally treated @entity1 with late onset of pregnancy care. As expected, in the groups of CSII and @entity5835 @entity1 no difference in the rate of pregnancy complications nor in fetal outcome could be demonstrated. Among CSII pregnancies 12/48 were complicated, in the @entity5835 population the respective figure was 13/41 ( @entity73200 ). The mean gestational age at the time of delivery ranged between 38 and 40 weeks, depending on the severity of @entity6 . CT @entity1 were delivered earlier in all White classes. Fetal morbidity was nearly equal in CSII and @entity5835 @entity1 , in CT @entity1 it was greatly enhanced. Also the mortality (perinatal and neonatal) was considerably larger in CT @entity1 (6/28), again, in the CSII and @entity5835 population the mortality was nearly identical (2/48 and 3/41). We conclude, from our prospective information, that insulin pump therapy during pregnancy is indicated if intensified conventional treatment does not lead to normoglycemia.(ABSTRACT TRUNCATED AT 250 WORDS)
