@entity15018 in New Zealand XXXX with @entity453 .

@entity1 @entity455 @entity583 @entity66 @entity13799 @entity15018 @entity453 @entity1718 @entity1851
BACKGROUND: Dietary surveys indicate that New Zealanders have a low intake of @entity15018 ( @entity13799 ) with little derived from industrial sources. This observational cross-sectional study in New Zealand @entity1 with surgical @entity453 assesses the plasma levels of @entity13799 and the association of @entity13799 levels with clinical markers of @entity455 . METHODS: 390 @entity1 with severe coronary artery had fasting blood tests taken. Plasma levels of four @entity13799 derived from hydrogenated vegetable oils and ruminant animal products were measured by gas chromatography. Relations between plasma @entity13799 levels and the recent occurrence of @entity583 , the presence of @entity66 , and serum levels of @entity1851 ( @entity1851 ) were assessed. RESULTS: The median @entity13799 level was 0.85% by weight of total @entity1718 (IQR 0.59-1.79%), with skewed distribution to the right. For the lowest (<0.74%), middle (0.74-1.07%), and highest (>1.07%) thirds of total @entity13799 , respectively, the proportion of @entity1 with @entity66 was 10%, 16%, and 27% (p   =   0.0004). Plasma @entity1851 also increased by tertile of @entity13799 (median 2.0, 2.9, 3.2   mg/l, p   =   0.007). The association with @entity66 and @entity1851 remained significant after adjustment for risk factors. Significant associations were present between plasma @entity13799 from both ruminant and hydrogenated vegetable oil sources and these markers of cardiovascular risk. CONCLUSIONS: There is an association between relatively low plasma levels of total @entity13799 , mostly derived from ruminant sources, and an increased risk of @entity66 and increased @entity1851 in @entity1 with severe @entity453 . These high-risk @entity1 may benefit from a targeted approach to minimize all sources of @entity13799 in the diet.
