XXXX : a single treatment for hyperuricaemia and @entity101 ?

@entity1 @entity8 @entity101 @entity3811 @entity3833 @entity158 @entity210 @entity551 @entity17084 @entity414
@entity17084 is a drug with established uricosuric and @entity551 properties. We have examined its potential role as a single treatment for hyperuricaemia and @entity101 , 2 disorders which are commonly associated. In 17 subjects with @entity210 , blood @entity414 levels were reduced by approximately 50%. Eleven of these @entity1 also had @entity101 which was improved by @entity17084 . However, a statistically significant effect was observed only with standing diastolic blood pressure. Side effects included acute episodes of @entity210 in 4 @entity1 and transient @entity158 and @entity3833 in 1 @entity1 . The precipitation of @entity3811 is an acknowledged risk of all potent hypouricaemic drugs. The hazard of urate deposition in the renal tract implicit in the history of @entity158 is a more serious complication. Thus, it would appear that @entity17084 is a potentially valuable drug which may have a special role in @entity1 with hyperuricaemia and @entity101 . Further study is necessary to determine how it may be best administered without the risk of @entity8 .
