Quality of life after surgical decompression for space-occupying XXXX : Systematic review.

@entity1 @entity308 @entity2500 @entity1188
BACKGROUND AND PURPOSE: In @entity1 with space-occupying @entity2500 , surgical decompression strongly reduces risk of death and increases the chance of a favorable outcome. This comes at the expense of an increase in the risk of survival with (moderately) severe disability. We assessed quality of life, @entity308 , and caregiver burden in these @entity1 . SUMMARY OF REVIEW: We systematically reviewed the literature by searching MEDLINE, EMBASE, and PsycINFO up to March 2014. We included randomized controlled trials, cohort studies, case-control studies, and case series with quality of life, @entity308 , or caregiver burden as primary or secondary outcome. Seventeen articles reporting on 459 @entity1 were included. At final follow-up at 7 to 51 months, 1344 @entity1 (30%) had died, and 34 (11%) were lost to follow up. Data on 291 @entity1 were available, of whom 81 of 213 survivors (39%) achieved good functional outcome at final follow-up (modified Rankin Scale  <=3). Mean quality of life was 46% to 67% of the best possible score when based on questionnaires or visual analogue scales. At final follow-up, 143 of 189 @entity1 (76%) would in retrospect again choose for surgical decompression. Severe @entity308 were present in 14 of 113 @entity1 (16%). Three studies investigated caregiver burden and reported substantial burden. @entity1 more than 60 years old had a lower quality of life in comparison with younger @entity1 . CONCLUSIONS: Most @entity1 treated with surgical decompression for space-occupying @entity1188 have a reasonable quality of life at long-term follow-up and are satisfied with the treatment received. Severe @entity308 are uncommon.
