In vitro antibacterial, phototoxic, and synergistic activity of XXXX extracts from Costus cf. arabicus L.

@entity1068 @entity581 @entity526 @entity794
In this study, @entity1068 extracts of stems and leaves of Costus cf. arabicus L. were evaluated for antibacterial activity against multidrug-resistant strains of @entity526 and @entity794 aureus. The antibacterial and modulatory activities of the extracts were assayed by microdilution. The light-enhanced antibacterial activity was assayed by a light regimen. The growth of the bacteria tested was not inhibited by the extracts. The minimum inhibitory concentration values were >= 1,024  g/mL. However, the antibiotic activity of @entity581 was synergistically enhanced when these extracts at subinhibitory concentrations were combined with the antibiotics. Also, both extracts showed activity against the wild-type bacterial strains, but the leaf extract was the more active extract, being active against both @entity794 and @entity526 . Therefore, we conclude that the @entity1068 extracts of stems and leaves of C. cf. arabicus L. have potential light-induced antibacterial activity and synergistic antibiotic activity. This study showed that these extracts may be a promising source of antibacterial and modulatory agents.
