Fine structure of the organic matrix of XXXX pancreatic stones.

@entity1 @entity788 @entity6220 @entity16127 @entity4959
Pancreatic stones that were removed from the pancreatic ducts of @entity1 with chronic calcifying @entity788 were decalcified so the organic matrix could be studied by scanning and transmission electron microscopy. The observations made by scanning electron microscopy were compared with those made on undecalcified stones, and the findings were correlated with light microscopic observations. After the @entity4959 was removed, the stones consisted of multiple partitions arranged like a sponge. They were embedded in a gel-like matrix. The organic partitions frequently were composed of dense surface layers and @entity6220 , which had surrounded and bound @entity4959 crystals. The organic matrix was heterogeneous in texture. Some areas had dense, regular, proteinaceous fibrous material. Deposits resembling fibrin were observed. Altered cellular constituents appeared to make up minor portions of the matrix. @entity4959 , which was precipitated in vitro in pancreatic juice, resembled the morphology of pancreatic stones more than that of pure @entity4959 crystals. These results are consistent with the coformation of pancreatic stones from constituents in the pancreatic juice [including @entity16127 ( @entity16127 ), glycosaminoglycans, and occasional cells] and precipitated @entity4959 .
