The Measurement of Intraocular Biomarkers in Various Stages of Proliferative XXXX Using Multiplex xMAP Technology.

@entity1 @entity650 @entity231 @entity6 @entity548 @entity7 @entity2533 @entity2297
Purpose. To determine the intraocular levels of growth factors and cytokines in @entity1 with various degrees of severity of @entity6 ( @entity6 ) using multiplex xMAP technology. Methods. A prospective cohort study of 61 eyes from 56 @entity1 who were divided into 3 groups based on the severity of @entity6 . @entity1 in group number 1 are those who presented @entity6 with no need of repeated surgical intervention; @entity1 in group number 2 had repeated @entity548 ; and @entity1 in group number 3 had @entity2297 . The concentrations of proangiogenic, antiangiogenic, inflammatory, and neurotrophic factors were measured in intraocular fluid. The results were also compared with levels of factors measured in 50 eyes from 50 @entity1 prior to senile @entity231 surgery (control group). Results. @entity1 with @entity2297 (the highest clinical severity group) had higher levels of @entity650 ( @entity650 ) (median1 37.19; median3 384.74; P = .00096), @entity2533 ( @entity2533 ) (median1 49.00; median3 414.40; P = .0017), and @entity7 ( @entity7 ) (median1 211.62; median3 352.82; P = .0454) compared with other @entity6 @entity1 . Conclusions. Results of our study imply that levels of @entity650 , @entity2533 , and @entity7 correlate with the severity of @entity6 .
