XXXX . Report of a case with cytologic, histologic and ultrastructural findings.

@entity1 @entity146 @entity5 @entity1325 @entity160 @entity2277 @entity4177
@entity4177 , although rare, is the most common primary @entity5 of the liver in @entity1 . In this paper we describe a case of @entity4177 with unusual cytologic features and present the histologic, immunocytochemical and ultrastructural features of this @entity5 . A 7-month-old @entity1 presented with a large hepatic mass and metastatic nodules in both lungs. Intraoperative biopsy revealed a @entity4177 . Aspiration biopsy yielded a highly cellular aspirate with cords of pleomorphic cells embedded in a mucoid matrix. Histologic sections showed a diffusely infiltrative @entity5 composed of sheets and cords of highly pleomorphic cells. The neoplastic cells stained strongly positive for cytokeratin CAM 5.2 and @entity1325 and focally positive for @entity160 , ferritin, carcinoembryonic antigen and @entity2277 . Ultrastructurally, the neoplastic cells had abundant intercellular junctions and intracytoplasmic aggregates of intermediate filaments. A mucoid matrix, to our knowledge, has not been reported as a finding on aspiration biopsy. This @entity1 presented with pulmonary metastases, and thus we think the mucoid matrix may be a marker of a more @entity146 . This case illustrates additional cytologic features of @entity4177 and the usefulness of aspiration biopsy in the rapid diagnosis of this rare @entity5 .
