The risk of XXXX in @entity1 with @entity1318 . A population-based study.

@entity5 @entity1 @entity1318 @entity418
OBJECTIVE: To determine more precise and accurate @entity5 risk estimates for @entity1318 that could be used to plan surveillance. DESIGN: Cohort. SETTING: Swedish population. @entity1 : All @entity1 with @entity1318 listed in the population-based Swedish Inpatient Register from 1964 through 1989. MAIN OUTCOME MEASURES: The observed number of @entity5 in the cohort was compared with expected numbers of @entity5 (standardized incidence ratio [SIR]) for each 5-year age group and calendar year of observation, calculated using data from the Swedish @entity5 Registry. RESULTS: A total of 1062 @entity1 with @entity1318 accumulated 9864 years of follow-up. The mean age at entry was 57.2 years, and the mean age at @entity5 diagnosis was 71.0 years. @entity418 occurred in 24 @entity1 . The risk of @entity418 in the first year after @entity1318 diagnosis was extremely high (SIR, 126.3; 95% confidence interval [CI], 63.0 to 226.1) as a consequence of prevalent @entity5 leading to distal esophageal obstruction simulating @entity1318 . During years 1 to 24, the risk was increased more than 16-fold (SIR, 16.6; 95% CI, 8.8 to 28.3). Annual surveillance after the first year would require 406 endoscopic examinations in @entity1 and 2220 in @entity1 to detect one @entity5 . CONCLUSIONS: @entity1 with @entity1318 are at markedly increased risk of developing @entity418 . A substantial number of surveillance examinations might be required to screen for @entity5 , especially in @entity1 . It is not known whether surveillance will result in improved survival.
