Palliative treatment of XXXX : value of small-bore catheter thoracostomy and @entity3403 sclerotherapy.

@entity1 @entity1143 @entity5 @entity3403 @entity158 @entity3483 @entity221
OBJECTIVE: This study evaluates small-bore catheter thoracostomy combined with @entity3403 sclerotherapy for palliative treatment of presumed @entity3483 . SUBJECTS AND METHODS: Forty-seven consecutive @entity1 referred from the medical oncology department to the thoracic radiology section with known primary @entity5 and symptomatic @entity1143 over a 2-year period were treated with small-bore pleural catheter drainage followed by @entity3403 sclerotherapy. Of the 47 @entity1 , 20 (43%) died less than 30 days after sclerotherapy, one (2%) died without radiographic follow-up, and five (11%) were lost to follow-up. Twenty-one @entity1 formed the study group. Response to treatment was defined based on findings on follow-up chest radiographs obtained 30 days after sclerotherapy as complete (no reaccumulation of @entity1143 ), partial (accumulation above postpleurodesis level but below that at presentation), or as a failure (reaccumulation to the amount seen at presentation). RESULTS: Seventeen (81%) evaluable @entity1 showed complete response to sclerotherapy, three (14%) showed a partial response, and one (5%) showed no response. All complete and partial responders were clinically improved with resolution of their shortness of breath. Therefore, 95% of evaluable @entity1 had clinically and radiographically successful treatment. Six @entity1 underwent sclerotherapy when their tube output was greater than 100 ml/24 hr. Five of the six had completely successful pleurodesis, and one failed to respond. Two (10%) of the 21 @entity1 had greater than 150 ml drainage in the 24 hr after initial @entity3403 administration and were therefore given a second dose of intrapleural @entity3403 . Both of these @entity1 subsequently had less than 150 ml drainage in an additional 24-hr observation period and went on to complete response. Complications included three @entity1 (14%) with mild discomfort at the chest tube site during drainage, one @entity1 (5%) with @entity158 during instillation of @entity3403 , and one @entity1 (5%) with transient @entity221 (38.3 degrees C body temperature) one day after sclerotherapy. CONCLUSION: Small-bore catheter thoracostomy followed by @entity3403 sclerotherapy successfully resolves symptomatic @entity1143 in @entity1 with known primary @entity5 .
