Radiofrequency ablation of peripheral @entity96 : intraperitoneal 5% XXXX in water decreases postprocedural @entity158 .

@entity1 @entity96 @entity1286 @entity158 @entity413
OBJECTIVE: Our objective was to evaluate the clinical efficacy of the intraperitoneal instillation of 5% @entity413 in water (D5W) during radiofrequency ablation of peripheral @entity96 for decreasing postradiofrequency @entity158 and narcotic use. MATERIALS AND METHODS: This case-control study compared the hospital course of the last 20 @entity1 to undergo radiofrequency ablation of peripheral @entity96 at our institution. Ten consecutive subjects in the D5W group (seven @entity1 and three @entity1 ; age range, 37-78 years; mean, 58 years) were pretreated with intraperitoneal D5W (average, 963 +/- 436 [SD] mL) before the ablation. This group was compared with a control group of 10 @entity1 (five @entity1 and five @entity1 ; age range, 36-73 years; mean, 54 years) who did not receive intraperitoneal D5W. The size of the ablation zone, degree of liver capsule involvement, number of burns, @entity1 -reported @entity158 , @entity1 -controlled analgesia use, and length of hospital stay were recorded and compared between the groups. RESULTS: The @entity1 in the D5W group reported significantly less @entity158 in the first 24 hr after the procedure than did the controls (2.3 vs 6.3, p = 0.003) despite a significant decrease in @entity1 -controlled analgesia use (17.3 vs 125.1 mg of @entity1286 , p = 0.003). The differences in @entity158 and @entity1 -controlled analgesia use were greatest in the first 16 hr and decreased over time in both groups. The total volume of ablation (61.9 vs 45.2 cm(3), p = 0.44), liver surface involvement (6.2 vs 6.0 cm, p = 0.73), and number of burns (1.8 vs 1.1, p = 0.14) were slightly higher in the D5W group than in the control group, but this difference was not statistically significant. CONCLUSION: Pretreatment with intraperitoneal D5W before radiofrequency ablation of peripheral @entity96 decreased @entity158 , narcotic use, and length of hospital stay. The effect of pretreatment with D5W is greatest in the first 16 hr after the procedure.
