XXXX : a study of associated risk factors.

@entity1 @entity66 @entity548 @entity39 @entity28 @entity532 @entity4125 @entity221 @entity13171 @entity1851
BACKGROUND: @entity532 include @entity548 , bullous, abscessing and @entity39 . The risk factors predisposing @entity1 to local complications are not fully known. AIM: To examine local complications of @entity13171 and to identify possible risk factors predisposing to their appearance. METHODS: Medical records from all @entity1 hospitalized with complications of @entity13171 ( @entity4125 , bullae, @entity39 ), admitted to the University Hospital of Heraklion between 1994 and 2002, were retrospectively studied. Clinical and laboratory data were compared with those from @entity1 with @entity13171 without local complications. RESULTS: In total, 145 @entity1 were analysed, of whom 46 had @entity66 . Using bivariate analysis, the factors significantly associated with disease complications were found to be age >=  51 years, @entity28 , longer duration of local symptoms, and @entity221 on admission. During hospitalization, increased @entity1851 level, isolation of pathogens, longer duration of @entity221 and/or presence of leucocytosis, absence of response to initial antibiotic therapy, and longer length of hospitalization were also associated with complications in the bivariate analysis. However, in the multivariate analysis, @entity28 (OR 4.489, 95% CI 1.719-11.725, P = 0.002) was the only independent factor associated with complicated @entity13171 . CONCLUSIONS: This study found @entity28 to be an independent risk factor for local complications, of @entity13171 . Hence, @entity28 @entity1 with @entity13171 are prone to complications, and should be carefully evaluated because of the potential severity of disease and the increased risk of failure of empirical antimicrobial therapy.
