Intermediate XXXX : long-term course and visual outcome.

@entity1 @entity1018 @entity227 @entity32 @entity738 @entity231 @entity4 @entity1596 @entity262 @entity1939 @entity370 @entity15
AIM: In this retrospective cohort study we investigated the long-term course and visual outcomes of intermediate @entity1596 (IU). METHODS: We performed an institutional study of @entity1 with IU with a follow-up of at least 10 years, followed at a tertiary referral centre. RESULTS: We studied 29 @entity1 with unilateral or bilateral IU. The average age at onset of IU was 31 (range 8-64) years. At onset, three @entity1 (10%) had associated @entity262 (two with @entity370 and one with @entity15 ) and one @entity1 had @entity738 annulare. During the follow-up period, one additional @entity1 was diagnosed with @entity370 and one with @entity15 . The percentage of eyes with @entity1939 and @entity227 gradually increased over time (from 9/53 (17%) at onset to 15/53 (28%) at 10-year follow-up), with @entity4 , @entity231 and vitreous opacities being the most common causes of @entity1018 . The presence of associated anterior @entity1596 was more frequently noted in @entity1 younger than 20 years at onset. Remissions of @entity32 of at least 1 year were noted in 10/29 (34%) of @entity1 . The mean time-to-remission was 8.6 years; @entity1 who had remissions were younger at the onset of IU than those with ongoing active IU (p = 0.036). Remissions of IU showed borderline association with the absence of @entity262 (p = 0.046). CONCLUSIONS: One-third of IU @entity1 achieved a remission of their @entity32 for longer than 1 year and had a mean time-to-remission of 8.6 years. @entity1 who were younger at onset of IU were more likely to achieve remission than those who were older at onset.
