Use of beta-blockers and effects on heart rate and blood pressure post- XXXX : are we on target?

@entity1 @entity1187 @entity1164 @entity1459 @entity1406 @entity583 @entity551
BACKGROUND: beta-blockers have been shown to benefit @entity1 after @entity583 by decreasing mortality, @entity1164 , and reinfarction. Although beta-blockers are recommended for all @entity1 with @entity1187 ( @entity1187 ) without contraindications, a target heart rate (HR) is recommended only for @entity1 with @entity1459 /non ST-elevation @entity583 . A contemporary series documenting trends in beta-blocker usage and achieved @entity551 (BP) is not available. The study objectives were to monitor trends in HR and BP in relation to beta-blocker use in a contemporary series of @entity1 with @entity1187 . METHODS: In this observational study, 300 consecutive @entity1 with proven @entity1187 had HR and BP values collected hourly from admission until hospital discharge and averaged at multiple intervals throughout hospital stay. Data on baseline demographic characteristics, beta-blocker doses, and titration schedules, procedures performed, cardiac regimens, concurrent medical issues, and contraindications to therapy were collected. RESULTS: Only 5.3% achieved an average HR of 50 to 60 beat/min throughout the hospital stay. Overall, the average HR was 74 beat/min and average BP was 115/64 mm Hg. Admission daily doses of @entity1406 averaged 58 mg compared to discharge daily doses of 88 mg; only 52% of @entity1 had dosage increases. CONCLUSIONS: Although effective levels of BP were maintained during hospitalization for an @entity1187 , target HRs were generally not achieved. Future studies are needed to determine the relationship between treatment objectives and clinical outcomes in the present era of @entity1187 management.
