Vascular invasion is not a risk factor in XXXX recurrence.

@entity5 @entity1 @entity2802
AIM: The outcome of the treatment of @entity5 remains poor despite improved treatment modalities and recurrence remains a major problem despite improved staging and treatment. The aim was to identify the independent risk factors responsible in the recurrence of @entity5 . METHODS: The @entity1 who had elective oesophagectomy (n = 244) with curative intent were studied. One hundred and eighty four @entity1 had surgery alone, 44 @entity1 had neo-adjuvant chemotherapy and surgery while 16 @entity1 had neo-adjuvant chemotherapy, surgery and adjuvant chemotherapy. We have analyzed @entity1 who had surgery alone (n = 184). Data was collected for demography, type of operation, histology, staging ( @entity2802 ), vascular invasion (VI), differentiation of @entity5 , type of chemotherapy and recurrence of @entity5 . RESULTS: The median age was 67 years (IQR 60, 71). The T1, T2, T3 distribution was 10%, 24% and 66% respectively. Forty percent had no nodal involvement (N0) and 60% had N1 stage disease. Twenty three percent of @entity1 had vascular invasion. Univariate analysis of histo-pathological factors identified lymph node yield (p = 0.06), curative resection R0 (p = 0.004) and vascular invasion (VI) (P = 0.69) as prognostic indicators of recurrence. Multivariate analysis showed that number of lymph nodes yielded (p = 0.01) and R0 resection remain independent indicators of recurrence of @entity5 . However, VI (p = 0.2) and age at disease onset (p = 0.8) were not indicators of recurrence in @entity5 @entity1 . CONCLUSION: R0 and lymph node yield may help to predict the recurrence of @entity5 . However the presence of VI may not be a significant risk factor in disease recurrence.
