SPECT perfusion patterns distinguish psychogenic from essential XXXX .

@entity1 @entity75 @entity1002 @entity400 @entity717 @entity13279
BACKGROUND: Psychogenic @entity717 pose formidable challenges to diagnosis and treatment reflecting our limited understanding of the basic brain mechanisms that cause them. Recently, functional brain imaging has been utilized to study @entity717 . OBJECTIVES: To identify characteristic patterns of cerebral perfusion distinguishing psychogenic @entity400 (PT) from essential @entity400 (ET). METHODS: We studied five @entity1 each with PT, ET and normal controls. SPECT imaging was performed at rest and during a @entity400 -inducing motor task. RESULTS: In ET, rest imaging revealed increased @entity13279 (relative cerebral blood flow) in cerebellar hemispheres and @entity75 . During the motor task, ET @entity1 demonstrated increased @entity13279 in the supplementary motor area (SMA) and contralateral motor cortex and reduced @entity13279 in the cerebellum and visual cortex. In contrast, PT images at rest revealed increased @entity13279 in @entity1002 . Motor task imaging revealed increased @entity13279 in the cerebellum and reduced @entity13279 in anterior regions of the default mode network. CONCLUSIONS: Our study revealed distinct patterns of cerebral perfusion during rest and motor task that distinguish PT from ET. Deactivation of the default mode network may serve as a marker for @entity717 .
