Immunohistochemical localization of @entity310 , XXXX and @entity1722 protein in hyperplastic human prostates.

@entity251 @entity310 @entity1067 @entity470 @entity7790 @entity406 @entity1486 @entity1722
@entity310 ( @entity7790 ) is a potent mitogenic factor which acts by binding to the epidermal growth factor (EGF). @entity1722 is a member of the EGF receptor family and is known to be associated with cellular growth and differentiation. The roles played by these factors in @entity1067 ( @entity1067 ) are not clearly known. In the present study, expression of these factors was investigated immunohistochemically in frozen and @entity406 fixed prostate tissues from subjects suffering from @entity1067 . Intracytoplasmic localization of @entity7790 was observed in the epithelium of nine out of 39 (23.07%) cases. Twenty-six out of 36 (72.22%) frozen @entity1067 tissues exhibited moderate to strong staining for immunoreactive @entity470 in the cell membrane. @entity1722 oncoprotein was localized in 35 out of 39 cases (89.74%) with the intensity of staining being variable. All nine cases positive for @entity7790 were also positive for both @entity470 and @entity1722 protein. Staining reaction had no correlation with the serum @entity251 , prostate specific acid phosphatase and @entity1486 levels. Immunohistochemical studies indicate the expression of @entity7790 , EGF receptor and @entity1722 protein in @entity1067 tissues. Further study is required to elucidate the precise roles played by these factors in benign growth of prostates.
