[Total pancreatectomy for mucinous XXXX ].

@entity1 @entity788 @entity6 @entity5 @entity8940 @entity299 @entity7157
AIM OF THE STUDY: To report our experience of total pancreatectomy (TP) in ten @entity1 with mucinous @entity788 (MPT), to discuss pre and peroperative investigations in the management of MPT, and operative, functional and carcinologic results after TP. @entity1 AND METHODS: This retrospective study from January 1985 to January 2001 included ten @entity1 , 5 @entity1 and 5 @entity1 (mean aged: 64 years). Six @entity1 underwent one step TP for @entity5 ( @entity5 ) in 5 cases, and multifocal @entity8940 in one case. Four @entity1 underwent a second step TP for @entity5 recurrence (2 @entity5 , and 2 @entity7157 ) which occurred 12 to 121 months post operatively (mean: 49 months). RESULTS: Post TP @entity6 was controlled by insulinotherapy (3 injections a day), except in one @entity1 who needed insulin administration through a pump. One @entity1 , with @entity7157 , died from @entity5 recurrence 18 months after TP and 140 months after the initial pancreaticoduodenectomy. One @entity1 died from @entity299 34 months postoperatively. The 8 other @entity1 were alive with a mean follow-up of 33 months (range 11-61 months). CONCLUSION: Curative surgery for mucinous @entity5 of the pancreas may require TP, which is indicated preoperatively according to imaging, or intraoperatively following surgical findings and frozen section of the pancreatic margin. Totalization of a previous partial pancreatectomy is mandatory in case of @entity5 persistence or recurrence in the pancreatic remnant. @entity6 can be managed successfully by a specialized team.
