Reproductive and gynecologic surgical experience in XXXX -exposed daughters.

@entity1 @entity2208 @entity249 @entity4743 @entity46 @entity5849 @entity4134 @entity4742
Information on reproductive history, gynecologic operations, and examinations was analyzed for 338 @entity4742 ( @entity4743 )-exposed and 298 unexposed @entity1 whose mothers participated in an evaluation of @entity4743 use in pregnancy 28 years ago. A history of infrequent menses (less often than every 36 days) was reported more commonly by the exposed @entity1 (32%) than by the unexposed @entity1 (15%) and the mean duration of menstrual flow was also less. A greater number of exposed @entity1 than unexposed @entity1 experienced @entity249 (53 versus 19). The reasons for these differences are not currently known. Comparison of the outcomes of first pregnancies showed a higher proportion of premature births, @entity2208 , and @entity5849 in the exposed @entity1 (P less than 0.001). The difference in the occurrence of @entity5849 was statistically significant (8 versus 0; P less than 0.005). An adverse pregnancy outcome was more likely in @entity4743 -exposed @entity1 with cervicovaginal ridges. However, when the outcome of all pregnancies were considered, 81% of the exposed @entity1 had at least one living @entity1 . More exposed @entity1 than unexposed @entity1 had gynecologic surgical procedures, which may, in part, be due to the increased medical surveillance of the exposed group. The spectrum of diseases at operation in both groups was similar. @entity4134 and @entity4134 were more commonly reported among the exposed @entity1 while the occurrence of @entity46 in both groups was similar. For the exposed @entity1 who had been examined at the Chicago Lying-In Hospital over a 4-year period, epithelial changes in the vagina had disappeared in 32% and cervicovaginal ridges had disappeared in 57%.
