Demographic patterns of cutaneous T-cell lymphoma incidence in Texas based on two different XXXX registries.

@entity1 @entity3217 @entity5 @entity1442 @entity42424 @entity37923
@entity42424 ( @entity42424 ) are rare, but potentially devastating @entity5 , with @entity3217 fungoides and S  zary Syndrome being the most common. In our previous study, we identified and described regions of geographic clustering of @entity37923 cases in Texas by analyzing ~1990 @entity1 using two distinct @entity5 registries. In the current work, we describe in detail demographic patterns for this @entity5 in our study population and apply logistic regression models to analyze the incidence of @entity37923 by sex, race, age, and clinical stage at the time of diagnosis. Furthermore, using Fisher's exact test, we analyze changes in incidence over time in the identified Houston communities with unusually high @entity37923 incidence. While @entity37923 primarily affects Caucasian individuals >55  years old, we confirm that it presents at a younger age and with more @entity1442 stages in African-American and Hispanic individuals. Also, we demonstrate a significant increase in @entity37923 incidence over time in the identified communities. Spring, Katy, and Houston Memorial areas had high baseline rates. Furthermore, a statistically significant disease surge was observed in these areas after ~2005. This report supplements our initial study documenting the existence of geographic clustering of @entity37923 cases in Texas and in greater detail describes demographic trends for our @entity1 population. The observed surge in @entity37923 incidence in the three identified communities further argues that this @entity5 may be triggered by one or more external etiologic agents.
