XXXX involving the "Streptococcus milleri" group: analysis of 19 cases.

@entity1 @entity5 @entity281 @entity733 @entity2259 @entity130
During a 3-year study period, 19 @entity1 at the University Hospital of Maastricht developed bloodstream infections with species of the "Streptococcus milleri" group, for an incidence of 0.33 per 1,000 admissions. The @entity1 ' median age was 48 years; the male-to-female ratio was 2.8. Eleven @entity1 (57.9%) had underlying diseases, among which @entity5 was predominant. Local @entity130 to the mucosal barrier was an important risk factor. An associated site of @entity281 was found most frequently in the abdominal and thoracic cavities (nine and five cases, respectively). @entity2259 was polymicrobial in four of 19 episodes. The 20 infecting S. milleri strains were identified to the species level; Streptococcus anginosus was the most prevalent (16 strains). Eight strains carried Lancefield group C. The isolates were sensitive to most antibiotics. @entity733 formation was documented in nine cases (47.3%); repeated drainage procedures were required in half of these episodes. Mortality was high (five of 19 @entity1 , or 26.3%).
