[Local treatment with @entity1 laryngeal squamous carcinoma draining lymph node lymphocytes in XXXX bearing @entity1 @entity189 xenografts].

@entity1 @entity2047 @entity5 @entity19 @entity189 @entity3
OBJECTIVE: To increase the number of the @entity5 draining lymph nodes lymphocytes (TDLNLs) in @entity5 site and study its anti- @entity5 effect. METHODS: @entity2047 -activated TDLNLs were administrated by local injection in 10 @entity19 bearing @entity1 @entity5 at 10(7) cells/ @entity19 , once a week for two weeks. As a control, 10 @entity19 bearing @entity1 @entity5 were injected with D-Hanks buffer solution. RESULTS: The volume and weight of TDLNLs treated @entity5 were significantly reduced in comparison with those of the control (P < 0.05). The observed histopathologic characteristics of treated @entity5 were @entity5 necrotic foci and increased infiltration of lymphocytes in @entity5 and around @entity5 vessels. Proliferation of spleen nodules was also observed in the treatment group. Remote @entity3 was not found in this group. In contrast with the control group, @entity5 necrosis and proliferation of spleen nodules were not observed and infiltration of lymphocytes in the @entity5 was not significant. There was a lung @entity3 in the control group. CONCLUSION: Local injection of TDLNLs is effective against @entity1 @entity189 xenografts in @entity19 . It also could stimulate the immunoresponse of hosts and probably decrease the chance of @entity5 @entity3 .
