Prognostic significance of skin involvement from mucosal tumors of the XXXX .

@entity1 @entity135 @entity957
OBJECTIVE: To examine the hypothesis that skin involvement from @entity957 of the @entity135 is a prognostic indicator of a poor outcome. DESIGN: Retrospective review of cases and statistical assessment of median survival times. @entity1 : @entity1 with @entity957 of the @entity135 . Fifteen @entity1 had direct skin extension and 11 @entity1 had intradermal lymphatic spread. SETTING: University medical center. RESULTS: Direct skin involvement was a prognostic sign of poor outcome but was less ominous than skin involvement by intradermal lymphatic spread. The @entity1 with direct involvement had a 7-month median survival; those with lymphatic spread had a 3-month median survival. At 3 years, all but one @entity1 had died. Involvement of facial skin was better prognostically for duration of survival than was involvement of neck skin. Surgical resection of the involved skin in half of the @entity1 extended palliation 20 months beyond the median survival of the other @entity1 . CONCLUSIONS: Skin involvement from @entity957 of the @entity135 indicates a poor prognosis, but resection offers short-term palliation.
