XXXX : spectrum of disease and imaging presentation.

@entity5 @entity1614 @entity242
OBJECTIVES: To describe the imaging findings of a series of myxoinflammatory @entity242 (MFSs) from our institution, including a case of dedifferentiated @entity1614 and two cases with areas of high-grade @entity5 , in addition to typical cases of low-grade @entity5 . To correlate the imaging findings with the pathologic features of these @entity5 . SUBJECTS AND METHODS: IRB approval was obtained. Retrospective search of the pathology database at our institution from 2000 to 2015 identified seven cases of @entity1614 with available imaging. Imaging, pathology, and clinical data were reviewed. RESULTS: Unlike the majority of well-differentiated @entity5 in our series (four cases), one @entity5 showed dedifferentiation and two cases had areas of high-grade @entity5 . The dedifferentiated @entity5 showed peripheral post-contrast enhancement. One case with a substantial high-grade component showed osseous destruction and peripheral enhancement in the high-grade area, while the low-grade component enhanced diffusely. The second case had a small high-grade area and showed diffuse enhancement. All three of these cases had non-acral locations and lacked association with a tendon. The four cases of low-grade @entity1614 demonstrated diffuse enhancement, were located in the distal extremities, and were associated with a tendon. CONCLUSION: The imaging findings of dedifferentiated and high-grade @entity1614 differ from the more typical @entity5 in that they have nonenhancing areas, a non-acral location, lack association with a tendon, and may involve bone. The radiologist should be aware that @entity1614 represents a spectrum that includes @entity5 , @entity5 with high-grade areas, and @entity5 with dedifferentiation and that this spectrum presents with differing imaging features.
