Treating @entity101 in hemodialysis improves symptoms seemingly unrelated to XXXX .

@entity1 @entity3887 @entity101 @entity1353 @entity5507 @entity1295 @entity3795 @entity3593 @entity2165 @entity65
BACKGROUND: Among hemodialysis @entity1 , probing dry weight is an effective strategy for improving control of @entity101 . Whether controlling @entity101 improves or worsens symptoms among such @entity1 remains unclear. The purpose of the study was to develop a tool to evaluate symptoms and examine the relationship of the change in these symptoms with blood pressure (BP) control. METHODS: Among @entity1 participating in the Hemodialysis @entity1 Treated with @entity2165 or @entity3593 (HDPAL) randomized controlled trial, a confirmatory factor analysis ( @entity3795 ) was performed to establish the relationship between symptoms and organ systems. Next, the change in symptom scores pertaining to organ systems was analyzed using a mixed model. Finally, the independent effect of lowering home BP on change in symptoms was evaluated. RESULTS: Among 133 @entity1 where symptoms were available at baseline, @entity3795 revealed four level 1 domains: gastrointestinal symptoms, dialysis-related symptoms, @entity65 and general symptoms. All except dialysis-related symptoms were ascribed to @entity5507 (level 2 domain). Uremic symptoms improved over 6 months and then increased. Dialysis-related symptoms ( @entity1295 ) did not worsen despite lowering home BP. Probing dry weight was independently associated with an improvement in @entity65 such as @entity1353 . CONCLUSIONS: Reducing BP through the use of a strategy that includes volume control and medication improves symptoms seemingly unrelated to @entity3887 . In long-term hemodialysis @entity1 , treating @entity101 using home BP measurements may improve well-being.
