[Amniotic membrane transplantation in severe XXXX . Preliminary results].

@entity1 @entity7499 @entity2372 @entity9849 @entity2687
PURPOSE: To evaluate amniotic membrane transplantation (AMT) in severe @entity2687 . METHODS: Amniotic membrane transplantation was performed in 14 eyes of 14 @entity1 from four groups: A, five severe ocular burns; B, four cases of @entity9849 ; C, three persistent epithelial defects after penetrating keratoplasty; D, two cases of @entity2372 . Five @entity1 underwent AMT alone; two @entity1 underwent AMT combined with limbal transplantation; the other three @entity1 had limbal transplantation performed before AMT. Eight @entity1 required combined penetrating keratoplasty. @entity1 with corneal stable reepithelialization, no @entity7499 , and no recurrence of the initial pathology were considered successful. RESULTS: The mean follow-up was 7+/-3 months. All but three @entity1 underwent corneal reepithelialization within 6 weeks of AMT, with a mean healing time of 31+/-23 days. The success rate was 75% at 6 months (Kaplan-Meier method). Three of four procedures in group B failed. In eight @entity1 , visual acuity improved, in one it worsened, and in the last five @entity1 it remained unchanged. Visual acuity increased by an average of 7+/-9 lines. CONCLUSION: AMT is a useful technique for ocular surface reconstruction, especially in association with limbal transplantation. It could also improve the prognosis of penetrating keratoplasty in @entity1 with severe corneal conditions.
