Hyperinfection syndrome in XXXX : report of two cases.

@entity1 @entity1712 @entity1252 @entity5506 @entity13739 @entity8143 @entity360
Hyperinfection in @entity13739 has been associated with corticosteroid treatment. Other immunodepressive conditions also seem to facilitate the state of hyperinfection. The etiologic diagnosis of this @entity8143 can be difficult to reach and a positive urine microscopy is unusual. We report two @entity1 under corticosteroid therapy with disseminated @entity13739 ; both had @entity1712 . The first @entity1 , followed for 8 years for @entity5506 , recently developed abdominal symptoms. A colonoscopy was performed 1 month before admission and the biopsy was thought to show nonspecific changes. At admission, few larvae of Strongyloides stercoralis were disclosed by urine microscopy, and a review of the colonic biopsy uncovered a few larvae of Strongyloides. The patient received anti-helmintic therapy with a dramatic improvement. The second @entity1 , under treatment for @entity1252 for 3 years, was admitted with pulmonary symptoms and during admission developed massive @entity360 . @entity13739 was discovered only at autopsy. The low suspicion index for @entity13739 resulted in delaying the etiologic diagnosis in one @entity1 and in failing to diagnose the disease in the other. The morphologic features of the parasite in the two cases are presented with emphasis on the difficulties of recognizing the larvae in the intestinal biopsy.
