[Importance of cytologic examination of urine in the diagnosis of XXXX ].

@entity1 @entity2803 @entity8 @entity4295 @entity740 @entity205 @entity631
BACKGROUND: This paper presents our experience with cytologic examination of urine in diagnosing @entity8 . METHODS: The study group included 23 @entity1 with @entity8 , selected from 56 @entity1 who underwent renal transplantation. Etiologic diagnosis was made according to the clinical picture, histological findings during allograft biopsy, and cytologic examination of urine. Urine sediment was obtained in cytocentrifuge and was air dried and stained with May Grunwald Giemsa. RESULTS: Out of 23 @entity1 with allograft dysfunction in 18 (78.3%) @entity1 it was caused by acute rejection, and in 5 (8.9%) @entity1 by allograft infarction, @entity205 nephrotoxicity, @entity4295 and chronic @entity8 . In eighteen @entity1 (78.3%) cytologic examination of urine was pathologic, while in 16 (70%) clinical and histology findings coincided with urine cytology findings. Out of 18 @entity1 with acute allograft rejection in 15 @entity1 cytologic examination of urine coincided with acute rejection. Out of 7 @entity1 with expressed @entity205 nephrotoxicity, in 5 cytologic examination of urine confirmed the cause of allograft dysfunction, as well as in one of 2 @entity1 with @entity4295 . Cytologic examination of urine indicated parenchymal damage in 2 @entity1 with recurrent disease (membranoproliferative and focal sclerosing @entity631 ). In 4 of 5 @entity1 suffering from chronic rejection in a year's monitoring period, urine sediment periodically consisted of lymphocytes, neutrophilic leucocytes, monocyte/macrophages, tubular cells and cylindres, without the predominance of any cell type. In 3 @entity1 allograft dysfunction was caused by infective agents (bacteria, fungus, @entity2803 ). CONCLUSION: Cytologic examination of urine might be an alternative to histological in diagnosing acute allograft rejection and @entity4295 or nephrototoxicity. Also it might indicate parenchymal disease while the importance of urine cytology in @entity740 needs to be investigated further.
