Is There a Relationship between Obstructive Sleep Apnea Syndrome Severity and XXXX ?

@entity1 @entity29869 @entity27 @entity28
BACKGROUND: @entity27 ( @entity27 ) and @entity28 frequently occur together. The relationship between increased appetite and @entity28 is well known; however, despite existing knowledge about the relationship between @entity27 and @entity28 , it is not fully understood. OBJECTIVES: This study aimed to evaluate the relationship between @entity27 and the appetite-suppressing hormone @entity29869 independent of body mass index (BMI). METHODS: A total of 134 cases were included in the study; 102 with @entity27 ( @entity27 group) and 32 healthy controls (control group). All cases underwent polysomnography, and @entity29869 levels were determined. RESULTS: @entity29869 levels were significantly lower in the @entity27 group compared to the control group (3,776.5    204.8 and 4,056.2    101.5 pg/ml, respectively; p < 0.001). In addition, there was a statistically significant negative correlation between @entity29869 and the @entity27 index (r = -0.543; p < 0.001). The statistically significant relationship persisted after adjusting for confounding intergroup factors such as age, gender and BMI (p < 0.001). In the @entity27 group, there was a statistically significant correlation between @entity29869 and neck circumference (r = -0.304; p = 0.02) but not between @entity29869 and BMI and waist circumference. There was no statistically significant difference in @entity29869 levels between the sexes. CONCLUSION: @entity27 @entity1 have lower @entity29869 levels compared to controls, and a greater @entity29869 deficit corresponds to an increased severity of @entity27 and an increased neck circumference. Replacement therapy may be a potential treatment for obese @entity27 @entity1 who have lower @entity29869 levels, which may have additional benefits through appetite suppression and weight loss.    2015 S. Karger AG, Basel.
