[Vascular changes in sporadic XXXX . Epidemiology, pathogenesis, clinical picture and diagnosis with particular consideration of angiographic documentation].

@entity548 @entity63 @entity1508 @entity1373 @entity6116 @entity999 @entity2704 @entity2473 @entity8327 @entity715 @entity2119 @entity4288
Whereas the epidemic form of @entity8327 has been rare in the 20th century, the sporadic form has a wide distribution as a consequence of therapy with ergot-derivative drugs. Favourable prognosis of the condition, with complete recovery from the @entity63 peripheral circulatory disorders can be obtained by early diagnosis. Precise evaluation of the history, with recognition of treatment of @entity2704 or @entity548 with ergot alkaloids, can be determinative in diagnosis. The specific pattern of the angiographic findings, as we saw it in 6 cases within the last 4 years, decisively confirms the diagnosis. We could demonstrate thread-, thorn- and hour glass-like narrowing of the vessels, due to @entity2473 . Total occlusion with the development of collaterals may occur, but we saw no @entity715 formation. The stenotic arterial segments had smooth margins. The distribution of the involved arteries was more focal than generalized and more peripheral than central. In two cases @entity2473 could be abolished immediately by a pharmaceutical (i.a. injection of @entity6116 ) or by anesthetic procedures ( @entity1508 ). The phenomenologic data, together with the complete reversal of the circulatory @entity63 after therapy (particularly the absolute ban of ergots) in most cases, is so specific that other diseases of @entity63 nature ( @entity999 , @entity4288 , @entity2119 , @entity1373 ) can be excluded.
