Pre- and postnatal diagnosis of XXXX : a series of 107 cases.

@entity1 @entity4218 @entity600 @entity2008 @entity85
This is a 3-year retrospective study of 107 cases presenting with @entity4218 detected either on prenatal ultrasound scan, or after birth. These @entity4218 are @entity600 , and can be isolated, syndromic, or associated with multiple @entity600 . Cases were ascertained through the prenatal diagnosis center, the pediatrics department, and the feto-pathology department. Several criteria were analyzed including sex ratio, prenatal diagnosis, karyotype, termination of pregnancies, clinical or pathological examination, pediatric or surgical and/or genetic assessment, and whether or not a diagnosis was made. @entity85 and syndactyly were excluded. @entity4218 were detected prenatally in 45% of the cases, and a diagnosis was made in 78%, including isolated, syndromic, or @entity2008 . Sixty-one per cent of the @entity1 had follow-up, either pediatric, surgical, or genetic. Prenatal multidisciplinary assessment is fundamental to assist with counseling, as is the post-natal follow-up of the @entity1 . The diagnosis, if made, will obviously influence the information that will be given to the parents and the management of the @entity600 . If the pregnancy is terminated, feto-pathological examination is essential to help make a diagnosis, and guide recurrence risks. We are currently undertaking a prospective study, and we will develop a protocol of investigations in the future, depending on the type of the @entity600 identified.
