A proposed classification of XXXX based on kinetic information: derived from a comparison of risk factors in 168 primary operable @entity0 .

@entity172 @entity0 @entity1420 @entity5 @entity1014 @entity3
Flow cytometric DNA analysis was performed on 168 consecutive primary operable @entity0 and the results correlated with @entity1014 labeling, @entity172 receptor (ER) and @entity1420 receptor values, and various histologic parameters. Seventy-five @entity5 (45.0%) were diploid and 93 (55.0%) aneuploid. In 83.9% of @entity5 , the DNA index fell between 1.1 and 2.0. Thirteen @entity5 were hypertetraploid and three hypodiploid. The percent of S-phase @entity5 (SpF) varied from 1.1% to 24.4%, with a mean of 8.0% and a median of 7.1%. The mean SpF of @entity5 was 5.2%; of @entity5 , 10.3%. There was no significant correlation between SpF or ploidy and @entity5 size or axillary lymph node status. The @entity1014 labeling index (TLI) varied from 0.2 to 23.1, with a mean of 7.5 and a median of 6.1. There was good correlation between TLI and SpF (r = 0.892, P = 0.0001). ER-negative @entity5 had a significantly higher mean SpF (10.3%) than did ER-positive @entity5 (6.7%), but there was no significant correlation between ploidy and receptor positivity or negativity. There was a good correlation between @entity3 , poor cytologic differentiation, aneuploidy, and above-median SpF. Only a fair correlation was observed between mitotic rate and SpF. A classification of invasive @entity0 based on ploidy and SpF is proposed.
