XXXX on a great toe: a case report.

@entity242 @entity8650 @entity5 @entity1313 @entity469 @entity241 @entity3291 @entity4483 @entity3778 @entity3074 @entity2280 @entity81
@entity3074 is a common benign @entity5 with many clinicopathological variants. @entity3074 is one of these variants, which is characterized by marked stromal mucin deposition. This report presents a case of @entity3074 on a great toe that had been slowly growing for two years. Histopathologically, the relatively well-circumscribed @entity5 was separated from the epidermis by a small grenz zone. The @entity5 tissue consisted of oval to spindle-shaped cells with well-defined cell borders and spindly condensed nuclei. No cytologic atypia or mitotic figures were found. Although most of the @entity5 cells were embedded in a prominently myxoid stroma, typical features of classic @entity3074 including a storiform growth pattern and more densely packed collagen were observed at the periphery. Immunohistochemically, the @entity5 cells showed positive staining for @entity469 and @entity3778 , and negative staining for @entity2280 and @entity4483 . Histopathological differential diagnoses of @entity3074 include @entity8650 with myxoid @entity5 stroma, such as superficial acral @entity81 , cellular digital fibroma, @entity3291 , @entity241 protuberans and low-grade @entity242 . Immunohistochemical staining can be useful in the differential diagnosis of these @entity5 . This case highlights the challenges encountered in the histopathological interpretation of @entity3074 . Pathologists should keep in mind the diagnosis of @entity3074 when dealing with @entity1313 arising on acral sites.
