Quantitative Analysis of Wall Shear Stress for XXXX Carotid Bifurcation at Cardiac Phases by the Use of Phase Contrast Cine Magnetic Resonance Imaging: Computational Fluid Dynamics Study.

@entity1 @entity455 @entity5173 @entity731 @entity1642
PURPOSE: Detailed strategy for regional hemodynamics is significant for knowledge of plaque development on @entity455 such as @entity731 . The aim of this study was to derive relation between @entity731 and hemodynamics at @entity1 carotid bifurcation by the use of @entity5173 ( @entity5173 ), and to provide more accurate hemodynamic information. METHODS: Blood velocity datasets at common carotid artery were obtained by phase-contrast cine magnetic resonance imaging (PC cine MRI). Carotid bifurcation model was computed for systolic, mid-diastolic, and end-diastolic phase. Comparison of @entity1642 ( @entity1642 ) was performed for each cardiac phase. RESULTS: PC cine MRI provided velocity measurement for common carotid artery with various cardiac phases. The blood velocity had acute variation from 0.21 m/s to 1.07 m/s at systolic phase. The variation of @entity1642 during cardiac phase was presented at carotid bifurcation model. High shear stress area was observed at dividing wall for all cardiac phases. The systole-diastole @entity1642 ratio was 10.15 at internal carotid side of bifurcation. And low shear stress (<0.5 Pa) was observed at internal carotid side of bifurcation. CONCLUSION: Bifurcation area represented low shear stress and changed significantly @entity1642 . The specific area with significant change in shear stress and low shear stress had good agreement with predilection sites of @entity731 . The result suggested that hemodynamics was related to @entity731 , and @entity5173 analysis with various cardiac phases that were provided by PC cine MRI was allowed to determine an accurate analysis condition. This led to the representation of hemodynamics in vivo.
