Percutaneous computed tomography-guided lung biopsy and XXXX : an assessment by intraoperative pleural lavage cytology.

@entity5 @entity1 @entity1143
BACKGROUND: Percutaneous computed tomography (CT)-guided needle biopsy remains one of the most important diagnostic tools in the management of lung nodules; however, it carries a risk of intrapleural dissemination of @entity5 cells. METHODS: CT-guided lung biopsy was performed before surgery in 171 (34.8%) of 491 @entity1 . A coaxial biopsy system was used that comprised a 19-gauge introducer needle and a 20-gauge core biopsy needle. A total of 412 (83.9%) of the 491 @entity1 underwent intraoperative pleural lavage cytology just after thoracotomy. Intraoperative pleural lavage cytology was performed immediately after opening the thorax, after the @entity1143 was gently washed with 50 mL of saline. RESULTS: No @entity1 had implantation of @entity5 cells in the chest wall after a median follow-up of 20.2 months. Intraoperative pleural lavage cytology results were positive for 5 (2.9%) of the 171 @entity1 who underwent CT-guided biopsy before surgery, in contrast to 13 (5.4%) of the 241 @entity1 who did not undergo biopsy before surgery. The difference between the biopsy and nonbiopsy groups was not statistically significant. When the analysis was limited to @entity1 with @entity5 , intraoperative pleural lavage cytology results were positive for 1 (0.8%) of the 128 @entity1 who underwent CT-guided biopsy, in contrast to 3 (2.7%) of the 110 @entity1 who did not undergo biopsy. This difference was also not statistically significant. CONCLUSIONS: No significant association was observed between percutaneous CT-guided lung biopsy and intraoperative pleural lavage cytology results, even in @entity1 with @entity5 . Percutaneous CT-guided lung biopsy with a coaxial needle does not seem to cause @entity1143 .
