Impact of sleeve gastrectomy on XXXX in a morbidly obese population undergoing bariatric surgery.

@entity1 @entity344 @entity354
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has established popularity as a weight loss procedure based on its success. However, LSG's effect on @entity354 ( @entity354 ) is unknown. OBJECTIVES: To analyze the incidence of @entity354 after LSG and to compare the results in @entity1 with preexisting and de novo @entity354 . SETTING: Tertiary Medical center. METHODS: The authors performed a retrospective review of primary LSG from 2005 to 2013 and compared @entity1 with pre-existing and de novo @entity354 who underwent LSG. RESULTS: A total of 919 @entity1 underwent LSG. @entity354 was present in 38 (4%) of the LSG cohort. We identified 2 groups: Group A consisted of 25 (3%) @entity1 with de novo @entity354 , and Group B consisted of 13 (1%) @entity1 with pre-existing @entity354 . Diagnosis of @entity354 in both groups was determined by symptoms and history of proton pump inhibitor (PPI) treatment, upper @entity344 , esophagogastroduodenoscopy, and pH manometry. In Group A, 1 (4%) @entity1 was managed with over-the-counter drugs, 17 (68%) @entity1 were treated with low-dose PPI, 6 (24%) @entity1 were treated with high-dose PPI, and 1 (4%) @entity1 was lost to follow-up. Group B consisted of 9 (69%) @entity1 treated with low-dose PPI and 4 (31%) @entity1 treated with high-dose PPI. Medical treatment failed in 4 @entity1 (10.5%) who subsequently required conversion to laparoscopic Roux-en-Y gastric bypass (LRYGB). In Group A, 1 @entity1 (4%) required LRYGB, and in Group B, 3 @entity1 (23%) required LRYGB. The outcome of conversion for Group A was incomplete resolution of symptoms in the 1 @entity1 , whereas in Group B, all 3 @entity1 (100%) had complete resolution of @entity354 symptoms after LRYGB. CONCLUSIONS: In this study, 3% of @entity1 developed de novo @entity354 , but most responded to either low- or high-dose PPI, with 4% requiring conversion to LRYGB.
