Expression of immunohistochemical markers according to histological type in @entity1 with XXXX .

@entity1 @entity7 @entity5091 @entity5962 @entity189 @entity2282 @entity3546 @entity5089 @entity420 @entity356
OBJECTIVE: We compared the biological characteristics of @entity356 ( @entity356 ) using immunohistochemical (IHC) staining among histological types. MATERIALS AND METHODS: IHC staining results were analyzed in 86 EGCs resected with endoscopic submucosal dissection to identify mucin phenotype and biological characteristics. RESULTS: The histological type was classified as @entity420 ( @entity420 ), mixed @entity420 (MAC), or @entity189 ( @entity189 ). Significant differences in @entity5091 (34.4% vs. 10.7%, p < 0.05) and @entity5089 (59.4% vs. 85.7%, p < 0.05) expression were observed between @entity420 and @entity189 . The poorly cohesive component of MAC showed stronger immunoreactivity to @entity2282 (46.2% vs. 14.3%, p < 0.05) but weaker reactivity to @entity5089 (57.7% vs. 85.7%, p < 0.05), compared to that of @entity189 . @entity5962 and @entity3546 expression levels significantly decreased in the poorly cohesive component of MAC (15.4% vs. 90.6%, p < 0.05; 7.7% vs. 90.6%, p < 0.05, respectively) and @entity189 (10.7% vs. 90.6%, p < 0.05; 14.3% vs. 90.6%, p < 0.05, respectively), compared to @entity420 . However, @entity7 expression significantly increased in the poorly cohesive component of MAC (42.3% vs. 9.4%, p < 0.05) and @entity189 (39.3% vs. 9.4%, p < 0.05), compared to @entity420 . CONCLUSION: IHC analysis showed that @entity356 histological types differ in terms of mucin phenotype and biological characteristics. The poorly cohesive components showed decreased @entity5962 and @entity3546 expression levels and increased @entity7 expression. These characteristics may contribute to the poor prognosis of @entity1 with MAC and @entity189 .
