OS101. The brain study: cognition, quality of life and social functioning following XXXX .

@entity1 @entity146 @entity73 @entity2673 @entity2704 @entity3036 @entity1468
INTRODUCTION: Previously preeclamptic @entity1 may express @entity73 , which have largely been ignored or attributed to the stresses of a complicated pregnancy. OBJECTIVES: This study aimed to identify the scope of neurocognitive and @entity2673 following @entity1468 . METHODS: Through website promotion and a mass e-mail members of the USA-based Preeclampsia Foundation who experienced @entity1468 in the past 20 years were invited to complete a web-based survey, consisting of a questionnaire about current and past medical health, the Cognitive Failures Questionnaire (CFQ), the abbreviated WHO Quality Of Life questionnaire (WHOQOL-BREF), and the Social Functioning Questionnaire (SFQ). @entity1 were stimulated to ask a friend who had a normotensive pregnancy to complete the survey as well (controls). @entity1 with current or past neurological conditions were excluded. Analysis was performed using Mann Whitney U test and linear regression. RESULTS: 966 cases and 342 controls were included. Median age was 34, median time since first pregnancy 4 and 5 years respectively. Cases scored significantly worse on all three questionnaires, and more often underwent @entity146 therapy, currently or in the past. There was a significant effect of @entity2704 on all questionnaires and of @entity3036 on CFQ score. Cronbach's alphas were >0.7, indicating good internal consistency of the questionnaires. Results are expressed as median (range) or number (percentage) (   )p<.001. CONCLUSION: Previously preeclamptic @entity1 report more @entity73 , and worse quality of life compared to @entity1 who had normotensive pregnancies. Health care providers and @entity1 should be aware of this so that affected @entity1 may receive recognition, psychological care and escape from the ignorance of their environment. Our findings may stimulate research relating to the origin and management of these important issues.
