XXXX Incidence and Mortality, United States 1999-2011.

@entity5 @entity1 @entity204 @entity1086
BACKGROUND: @entity1086 is a rare @entity5 with unusual distribution, and few population-based estimates for the United States have been published. METHODS: Using population-based @entity5 incidence and mortality data, we examined U.S. @entity1086 incidence and @entity204 rates for 2007-2011 and trends for 1999-2011. RESULTS: During 2007 to 2011, approximately 3,700 @entity1 were diagnosed with primary @entity1086 (rate = 1.13 cases per 100,000) and 2,000 died from the disease (rate = 0.62 @entity204 per 100,000) each year in the United States. Two thirds of @entity1086 cases and @entity204 occurred among @entity1 . @entity1086 incidence and @entity204 rates were three times higher among American Indian and Alaska Native @entity1 than non-Hispanic white @entity1 . By state, @entity1086 incidence and @entity204 rates ranged by about 2-fold. During 1999 to 2011, @entity1086 incidence rates decreased among @entity1 but remained level among @entity1 ; @entity204 rates declined among @entity1 but stabilized among @entity1 after declining from 1999 to 2006. @entity1086 incidence rates increased in some subgroups, notably among black @entity1 , those aged <45 years, and for endocrine @entity5 . CONCLUSIONS: Data from U.S. population-based @entity5 registries confirm that @entity1086 incidence and @entity204 rates are higher among @entity1 than @entity1 , highest among American Indian and Alaska Native @entity1 , and differ by region. While overall incidence and @entity204 rates decreased during 1999 to 2011, incidence rates increased among some small subgroups. IMPACT: Surveillance of @entity1086 incidence and mortality, particularly to monitor increases in subgroups, may provide clues to etiology and stimulate further research.
