Association of the number of sentinel lymph nodes harvested with survival in XXXX .

@entity1 @entity1600 @entity0 @entity66
AIMS: In @entity1 with @entity0 , the association between the number of @entity1600 ( @entity1600 ) removed and survival is poorly known. Our objective was to evaluate this association on @entity66 ( @entity66 ). METHODS: Data of 144 517 @entity1 with invasive T1-3M0 @entity0 and initial treatment with @entity1600 biopsy were extracted from the SEER database. Univariate and multivariate analyses were performed. RESULTS: The number of SLNs harvested and the completion of @entity1600 ( @entity1600 ) were not associated with @entity66 improvement for @entity1 without metastatic nodes. After adjustment, @entity1 with three SLNs had a better @entity66 than did other groups (HR of 0.73 CI 95% [0.60-0.88], p  =  0.001). This result was mainly driven by the group of @entity1 with one metastatic LN. When @entity1 had two or more metastatic LNs, there was no difference in @entity66 according to the number of SLNs or to completion of @entity1600 . CONCLUSIONS: The number of @entity1600 harvested was associated with @entity66 . According to @entity66 , the optimal number of SLNs harvested was three in this large series, thereby calling into question the understaging or undertreatment of @entity1600 biopsy in which only one or two SLNs are harvested but also the therapeutic effect of completion @entity1600 .
