The effect of revascularization of XXXX on coronary flow reserve and peripheral endothelial function.

@entity1 @entity712 @entity101 @entity384 @entity2791 @entity740 @entity450 @entity4341 @entity4346 @entity453 @entity299 @entity731
BACKGROUND: @entity1 with @entity731 ( @entity731 ) are at increased risk of @entity299 because of associated @entity101 , @entity453 , @entity712 and @entity740 . Although suggested to be beneficial, the cardiac effects of renal artery revascularization have not been well characterized. Our aim was to analyze the effects of percutaneous dilatation of @entity2791 ( @entity2791 ) in @entity731 @entity1 on coronary and peripheral vascular function. METHODS: Nineteen @entity731 @entity1 [11 females and 8 males, age at study entry (mean    SD) 69    10 years] were treated by dilatation of unilateral (n = 9) or bilateral (n = 10) @entity2791 , mainly because of uncontrolled or refractory @entity101 . The @entity1 were studied before and after the procedure (103    29 days). They underwent echocardiography and peripheral artery endothelial function testing using @entity384 ( @entity384 ) of brachial artery at rest and during reactive @entity450 . Myocardial blood flow was measured using quantitative PET perfusion imaging at baseline and during @entity4341 -induced @entity450 . RESULTS: Peripheral endothelial function, tested by @entity384 , as well as systolic blood pressure and left ventricular mass were improved in @entity1 with bilateral @entity2791 . However, myocardial perfusion and coronary flow reserve (CFR) did not change after the @entity2791 dilatation. CONCLUSION: This is the first study to analyze the stage of myocardial perfusion and CFR in @entity731 @entity1 . Although peripheral endothelial function, systolic blood pressure and @entity4346 were improved in @entity1 with bilateral @entity2791 by revascularization of @entity2791 , it did not have any effect on coronary perfusion.
