Laser surgery of early XXXX in elderly.

@entity5 @entity1 @entity957 @entity1803
Aim of this retrospective study is to evaluate the impact of transoral laser surgery of early @entity5 in elderly @entity1 in terms of feasibility, disease-free survival, overall survival and organ preservation, in a single Institute (European Institute of Oncology). A total of 122 @entity1 (male/female ratio 113/9), over 70s with untreated early stage @entity5 , were consecutively evaluated and treated at the European Institute of Oncology from 2000 to 2008. None had contraindications to general anaesthesia and all @entity1 signed informed consent to this surgical treatment. The severity of pre-operative comorbidities and the intra-operative risk were evaluated according to the American Society of Anaesthesiologists Grading classification. All @entity1 underwent laser cordectomies according to the European Laryngological Society classification. Histopathological examination demonstrated no evidence of @entity5 (pT0) in 19 @entity1 (calculated only in @entity1 with a previous vocal cord biopsy positive for @entity957 ), pTis in 18, pT1a in 53, pT1b in 16, pT2 in 14 and @entity1803 in 2, respectively. A 10-year overall survival, a @entity5 specific survival and a @entity5 -specific survival were, respectively, 64.9%, 84.8% and 94.3%. In conclusion, transoral laser surgery is feasible in elderly @entity1 with early stage @entity5 , providing good results in terms of disease-free survival, organ preservation and quality of life. Our group of elderly @entity1 had no intra-operative or post-surgical complications and resumed normal activities the day after discharge from hospital. Considering these factors, we can assess, that transoral laser surgery, therefore, represents a modern treatment that should be offered as an alternative to conventional radiotherapy in elderly @entity1 with early @entity5 referred to medical centres with expertise for this surgical procedure.
