The choice of estimating equations for glomerular filtration rate significantly affects the prevalence of XXXX in a multi-ethnic population during health screening.

@entity1 @entity644 @entity8 @entity470 @entity740 @entity633 @entity72398 @entity1011 @entity811
BACKGROUND: @entity1 present to the National University Hospital of Singapore and select one of several health screening packages after counselling. The prevalence of @entity740 ( @entity740 ) in this population when different glomerular filtration rate (GFR) estimating equations are used has not been examined. METHODS: Demographic data and urinalyses of @entity1 from 2000 to 2005 were extracted from laboratory computer databases and analysed. @entity740 was classified into stages according to the US National Kidney Foundation guidelines by @entity470 (mL/min per 1.73 m(2)) using the four-variable Modification of Diet in @entity8 equation. GFR of ethnic Chinese was also estimated using Ma's equation 8 (cGFR). Stage 1 and normal ( @entity470 or cGFR > 90) was discriminated by urinary microscopy or dipstick for @entity644 , @entity633 , @entity811 or leukocyturia. RESULTS: There were 3979 screenings (55.9% males, 61.9% Chinese). Means: age = 47.0 +/- 12.3 years, @entity1011 = 80.1 +/- 26.5 micromol/L, @entity470 = 89.6 +/- 19.7, cGFR = 110.8 +/- 23.8 and ( @entity470 + cGFR) = 102.5 +/- 24.9. By @entity470 in all @entity1 , the prevalence of @entity740 was 45.7%, 50.6%, 3.3%, 0.3% and 0.08% for stages normal @entity72398 , respectively. For Chinese @entity1 only, @entity470 and cGFR resulted in a different distribution ( @entity470 %/cGFR%): 24.9/50.5, 15.2/29.3, 56.8/19.7, 3/0.8, 0.2/0.2, 0/0 for stages 'Normal', 1, 2, 3, 4 and 5, respectively (P < 0.001). CONCLUSION: The prevalence of moderate to severe @entity740 (stage 3 to 5) in @entity1 presenting for health screening in Singapore was 3.7%. Notably, the prevalence of mild to moderate @entity740 (stages 1, 2 and 3) in Chinese @entity1 was affected significantly by the choice of GFR estimating equation.
