The Anti-Inflammatory Actions of Auricular Point Acupressure for XXXX .

@entity1 @entity650 @entity1643 @entity1356 @entity10132 @entity158 @entity1199 @entity3646
Background. Auricular point acupressure (APA) is a promising treatment for @entity158 management. Few studies have investigated the physiological mechanisms of APA analgesics. Method. In this pilot randomized clinical trial (RCT), a 4-week APA treatment was used to manage @entity1643 ( @entity1643 ). Sixty-one @entity1 were randomized into a real APA group (n = 32) or a sham APA group (n = 29). Blood samples, @entity158 intensity, and physical function were collected at baseline and after 4 weeks of treatment. Results. Subjects in the real APA group reported a 56% reduction of @entity158 intensity and a 26% improvement in physical function. Serum blood samples showed (1) a decrease in @entity1356 , @entity1199 , @entity650 , and @entity10132 [ @entity10132 ] and (2) an increase in @entity3646 . In contrast, subjects in the sham APA group (1) reported a 9% reduction in @entity158 and a 2% improvement in physical function and (2) exhibited minimal changes of inflammatory cytokines and neuropeptides. Statistically significant differences in @entity3646 and @entity10132 expression between the real and sham APA groups were verified. Conclusion. These findings suggest that APA treatment affects @entity158 intensity through modulation of the immune system, as reflected by APA-induced changes in serum inflammatory cytokine and neuropeptide levels.
