[Interstitial XXXX in @entity370 . Effect of corticosteroid therapy and long-term evolution. Retrospective study of 22 cases].

@entity1 @entity8 @entity738 @entity1986 @entity1011 @entity370 @entity454
@entity1986 ( @entity1986 ) with or without epithelioid @entity738 is the most frequent form of @entity8 in @entity370 . Nevertheless, few studies have provided conclusions about its treatment and long-term outcome. We report 22 cases collected over a 20-year period in 9 nephrologic departments of the west of France. We discuss the criteria which permit @entity370 to be distinguished from other causes, particularly of @entity1986 drugs. Twenty @entity1 were treated with corticoids. In 18 the result could be evaluated on at least 12 months. In 11 there was a decrease of plasma @entity1011 (Pc) and in 8 of these cases this decrease reached 50%. Of the 12 who were followed from 1 to 17 years, 4 obtained a reduction of Pc of at least 50%. These improvements occurred even in @entity1 whose Pc was initially higher than 300 mumol/l. Only 2 @entity1 reached @entity454 and hemodialysis within the observation period, one as early as the first month, the other after 6 years. Five relapses were observed after stopping treatment but 4 responded again favorably upon resumption. Two @entity1 who received no treatment at all nevertheless had stabilization or improvement of their renal function with a follow-up of 5 years for one case. It may be concluded that the long-term prognosis of @entity370 @entity1986 can be fairly good but there is no proof that it depends mainly on corticosteroid therapy.
