XXXX shows the same HLA class II pattern as @entity1723 .

@entity1 @entity8167 @entity6 @entity3098 @entity1669 @entity1723 @entity195 @entity12010 @entity792 @entity1533 @entity4107
@entity12010 ( @entity12010 ) type 2 is defined by the manifestation of at least two @entity792 . Only few data exist on genetic associations of @entity12010 . In this controlled study, 98 @entity1 with @entity12010 , 96 @entity1 with @entity1723 ( @entity1723 ), and 92 @entity1 with @entity1669 , both as a single @entity792 , were tested for association with alleles of the human @entity4107 loci @entity1533 , @entity8167 , and @entity3098 . @entity1 with @entity12010 had significantly more often the alleles @entity1533 *03 (P(c) < 0.0001), @entity1533 *04 (P(c) < 0.000005), @entity8167 *03 (P(c) < 0.0001), and @entity3098 *02 (P(c) < 0.05), when compared with controls. Less frequent in @entity12010 were @entity1533 *15 (P(c) < 0.05), @entity8167 *01 (P(c) < 0.0005), and @entity3098 *05 (P(c) < 0.005). With regard to frequency and linkage of these alleles, the susceptible haplotypes @entity1533 *0301- @entity8167 *0501- @entity3098 *0201 and @entity1533 *0401/04- @entity8167 *0301- @entity3098 *0302 were deduced. Protective haplotypes in this study were @entity1533 *1501- @entity8167 *0102- @entity3098 *0602 and @entity1533 *0101- @entity8167 *0101- @entity3098 *0501. Comparing @entity12010 @entity1 with vs without @entity195 , no significant differences regarding HLA class II alleles were noted in our collective. @entity1 with @entity1723 as a singular disease had the same susceptible and protective HLA alleles and haplotypes. The prevalence of @entity1533 *03 and @entity1533 *04 in @entity12010 @entity1 was not because of the presence of @entity6 , as the @entity12010 @entity1 without @entity6 had the same allele distribution. In conclusion, these data suggest a common immunogenetic pathomechanism for @entity1723 and @entity12010 , which might be different from the immunogenetic pathomechanism of other @entity792 .
