Incidence, ocular findings, and systemic associations of XXXX : a population-based study.

@entity1 @entity851 @entity11339 @entity2788 @entity4643 @entity74 @entity299 @entity16453 @entity2169 @entity790
OBJECTIVE: To describe the incidence, ocular findings, and systemic associations of @entity4643 in a population-based cohort of @entity1 . METHODS: We retrospectively reviewed the medical records of pediatric (aged <19 years) @entity1 diagnosed as having @entity4643 from January 1, 1968, through December 31, 2007, as residents of Olmsted County, Minnesota. RESULTS: Thirty-three @entity1 were newly diagnosed as having @entity4643 (annual incidence, 2.4 per 100,000 residents <19 years old; prevalence, 1 in 2077 live births). Median @entity1 age at diagnosis was 3.9 months (range, 2 days to 18.4 years), and 22 @entity1 (67%) had unilateral involvement. Twelve @entity1 (36%) had involvement of the anterior segment only, 13 (39%) of the posterior segment only, and 8 (24%) of both. During median ophthalmologic follow-up of 9.2 years (range, 13 days to 35.9 years), 19 @entity1 (58%) had other @entity2788 , including amblyopia in 11 (33%) and strabismus in 10 (30%). During median medical follow-up of 16.8 years, 22 @entity1 (67%) were diagnosed as having a @entity74 , including abnormal development in 12 (36%) and @entity11339 ( @entity4643 , @entity299 , @entity16453 , @entity851 and development, @entity790 , and @entity2169 ) syndrome in 4 (12%). CONCLUSIONS: @entity4643 occurred in 1 in 2077 live births. More than half of the @entity1 were diagnosed as having an @entity2788 other than @entity4643 , including strabismus and amblyopia in approximately one-third. Two-thirds of @entity1 were diagnosed as having a @entity74 , including @entity11339 in 1 in 8 @entity1 .
