Preoperative pulmonary function tests predict mortality after surgical or transcatheter XXXX .

@entity1 @entity26 @entity886 @entity358 @entity230 @entity472
OBJECTIVES: To determine the role of preoperative pulmonary function tests (PFTs) in @entity1 with @entity472 ( @entity472 ) evaluated for @entity886 ( @entity886 ), and to evaluate the association between @entity358 and mortality in specific subgroups. METHODS: Between 2008 and 2013, 535 @entity1 with preoperative PFTs underwent @entity886 (transcatheter @entity886 [TAVR], n  =  246; surgical @entity886 [SAVR], n  =  289). The severity of @entity358 determined by the Society of Thoracic Surgeons (STS) definition was evaluated in those with and without a clinical suspicion for @entity358 (smoking, inhaled @entity230 /bronchodilators, or home @entity26 ). The association between @entity358 and 1-year mortality was evaluated. RESULTS: Of the 186 @entity1 (35%) without suspected @entity358 , 39 (21%) had  moderate/severe @entity358 by PFT analysis. Among all @entity1 , 1-year mortality was 12% in those with no @entity358 , 17% in those with no mild @entity358 , 22% in those with moderate @entity358 , and 31% in those with severe @entity358 (P  <  .001, log-rank test). After adjustment, moderate/severe @entity358 was associated with increased 1-year mortality (adjusted hazard ratio, 2.07; 95% confidence interval, 1.30-3.29; P  =  .002); this association was not altered by smoking history, suspicion of @entity358 , New York Heart Association class, or @entity886 type (interaction P value nonsignificant for all). CONCLUSIONS: In @entity1 with @entity472 evaluated for @entity886 , the STS risk score is significantly influenced by the severity of @entity358 , which is determined predominantly by PFT results. Even when @entity358 is not suspected, PFTs are abnormal in many @entity1 undergoing @entity886 . Moderate/severe @entity358 , diagnosed predominantly by PFTs, is an independent predictor of mortality after SAVR or TAVR. Collectively, these findings suggest that PFTs should be a routine part of the risk stratification of @entity1 considered for @entity886 .
