Secondary prognosis after XXXX of atrial origin: the role of left @entity955 .

@entity1 @entity64 @entity117 @entity999 @entity955 @entity204 @entity1229
BACKGROUND: Secondary prevention studies for @entity64 show a remarkable variability in @entity64 recurrence rates. Various reports have raised questions regarding differences in baseline clinical characteristics and in methodology to explain this wide variability. HYPOTHESIS: The purpose of the present study is to examine the 2-year outcome after first @entity64 of atrial origin and to correlate secondary prognosis with left @entity955 . METHODS: Baseline evaluation included computed tomographic and/or magnetic resonance scanning, Doppler scanning, digital subtraction angiography, and transthoracic and transesophageal echocardiography to establish the diagnosis of @entity999 . Twenty-six @entity1 in nonrheumatic @entity955 and 13 in sinus rhythm were followed for recurrent @entity64 as endpoints (event +/-). RESULTS: @entity1 in sinus rhythm had a total of 23% (standard deviation +/- 12%) recurrence rate. All event (+) @entity1 were on @entity117 and died from this second @entity64 . Of @entity1 in nonrheumatic @entity955 , 50% were event (+) at the end of the first year ( @entity204 rate 46%). @entity1 on @entity1229 therapy had 20% recurrence rate versus 70% on @entity117 (relative risk 0, 18, 95% confidence interval, 0.05-0.48, p 0.041). Inward peak velocity of left @entity955 was the only echocardiographic variable significantly reduced in event (+) @entity1 (21 +/- 7 vs. 31 +/- 17 cm/s, p 0.048). CONCLUSIONS: @entity1 with nonrheumatic @entity955 and first @entity64 are at increased risk for recurrence if severe dysfunction of the left @entity955 is present and if they do not receive @entity1229 treatment. @entity1 with sinus rhythm and first @entity64 form a small @entity64 subgroup, in which recurrences are accompanied by a remarkably high @entity204 rate.
