Silent XXXX events after Pipeline embolization device: a prospective evaluation with MR diffusion-weighted imaging.

@entity1 @entity2806 @entity63 @entity16 @entity439 @entity1031 @entity3075
BACKGROUND: The development of @entity63 events is relatively common after endovascular interventions, and flow diverters may pose a particular threat owing to their increased technical complexity and high metal content. OBJECTIVE: To investigate the incidence and potential risk factors for @entity1031 after treatment with a Pipeline embolization device (PED). METHODS: This prospective study included a total of 59 @entity1 electively treated with a PED over 12   months. Postprocedural diffusion-weighted imaging sequences of the brain were obtained 24   h after interventions to detect @entity2806 . Demographic data, @entity439 characteristics, antiplatelet management, and perioperative data were correlated with the rate of @entity63 events. RESULTS: The incidence of silent @entity63 events after use of a PED was 62.7% (37 @entity1 ) and @entity16 occurred in 8.1% of affected @entity1 . Development of @entity63 events was significantly associated with older @entity1 (>= 60   years; p=0.038). Routine use of platelet function assays and newer @entity3075 receptor inhibitors (ticagrelor) were not associated with fewer @entity1031 . CONCLUSIONS: @entity1031 events are relatively common after treatment with a PED with an incidence comparable to stent-assisted and conventional coiling but the risk of @entity16 from @entity63 burden is low. Older @entity1 are at particularly increased risk of @entity1031 .
