XXXX : clinical character, investigation, and outcome.

@entity1 @entity2321 @entity712 @entity6016 @entity55 @entity8314 @entity1252 @entity3830 @entity2526 @entity358 @entity272 @entity6015 @entity2406
@entity8314 is an uncommon maternal auto-antibody-associated disease characterized by cutaneous, cardiac, hepatic, hematological, neurological, and @entity358 . A retrospective study was performed to review clinical manifestations, investigation results, outcomes of @entity8314 @entity1 and their mothers at the Department of Pediatrics, Siriraj Hospital during 1993 to 2008. Seventeen @entity8314 @entity1 (10 @entity1 and seven @entity1 ) were identified. Cutaneous, cardiac, hepatobiliary, and hematological involvement was found in 70.6%, 64.7%, 52.9%, and 35.3% of @entity1 , respectively. @entity272 were erythematous patches (91.7%), subacute @entity3830 (50%), petechiae (41.7%), persistent @entity2321 marmorata (16.7%), and discoid lesions (8.3%). @entity6015 was found in nine cases, and @entity2526 were found in nine cases. All sera of @entity1 were positive for antinuclear antibodies. Patients (87.5%) showed positive antiRo/SSA, and 50% had positive antiLa/ @entity6016 antibodies. Most @entity8314 mothers (64.7%) were asymptomatic. Five mothers were diagnosed with @entity1252 , and one mother was diagnosed with @entity2406 . All maternal sera was positive for antinuclear antibodies and antiRo/SSA antibody. Seven @entity1 required pacemaker implantation. The mortality rate was 11.8%, caused by @entity712 and @entity55 . Antinuclear antibody tests should be used as one of the screening tests in mothers or @entity1 suspected of having @entity8314 .
