Cumulative prevalence of XXXX by young adulthood: a prospective cohort analysis from the Great Smoky Mountains Study.

@entity1 @entity74 @entity952 @entity146
OBJECTIVE: No longitudinal studies beginning in childhood have estimated the cumulative prevalence of @entity146 from childhood into young adulthood. The objective of this study was to estimate the cumulative prevalence of @entity146 by young adulthood and to assess how inclusion of not otherwise specified diagnoses affects cumulative prevalence estimates. METHOD: The prospective, population-based Great Smoky Mountains Study assessed 1,420 @entity1 up to nine times from 9 through 21 years of age from 11 counties in the southeastern United States. Common @entity146 were assessed in childhood and adolescence (ages 9 to 16 years) with the @entity1 and Adolescent Psychiatric Assessment and in young adulthood (ages 19 and 21 years) with the Young Adult Psychiatric Assessment. Cumulative prevalence estimates were derived from multiple imputed datasets. RESULTS: By 21 years of age, 61.1% of @entity1 had met criteria for a well-specified @entity146 . An additional 21.4% had met criteria for a not otherwise specified disorder only, increasing the total cumulative prevalence for any @entity74 .5%. Male subjects had higher rates of substance and @entity952 compared with female subjects; therefore, they were more likely to meet criteria for a well-specified disorder (67.8% vs 56.7%) or any disorder (89.1% vs 77.8%). @entity1 with a not otherwise specified disorder only were at increased risk for a well-specified young adult disorder compared with @entity1 with no disorder in childhood. CONCLUSIONS: Only a small percentage of young @entity1 meet criteria for a @entity74 at any given time, but most do by young adulthood. As with other medical illness, @entity146 is a nearly universal experience.
