The changing face of hospitalisation due to XXXX and perforation.

@entity1 @entity548 @entity117 @entity1066 @entity344 @entity694 @entity360
BACKGROUND: Temporal changes in the incidence of cause-specific @entity344 may be one of the factors underlying changing medical practice patterns. AIM: To report temporal changes in the incidence of five major causes of specific @entity344 events. METHODOLOGY: Population-based study of @entity1 hospitalised due to @entity360 and perforation from 1996 to 2005 in Spain. We report crude rates, and estimate regression coefficients of temporal trends, severity and recorded drug use for five frequent GI events. GI hospitalisation charts were validated by independent review of large random samples. RESULTS: The incidence per 100 000 @entity1 -years of hospitalisations due to @entity360 and perforation decreased over time [from 54.6 and 3.9 in 1996 (R   = 0.944) to 25.8 and 2.9 in 2005 (R   = 0.410) respectively]. On the contrary, the incidence per 100 000 @entity1 -years of @entity694 increased over time [3.3 and 0.9 in 1996 (R   = 0.443) and 8.0 and 2.6 in 2005 (R   = 0.715) respectively]. A small increasing trend was observed for the incidence per 100 000 @entity1 -years of intestinal perforations (from 1.5 to 2.3 events). Based on data extracted from the validation process, recent recorded drug intake showed an increased frequency of anticoagulants with @entity694 , whereas NSAID and low-dose @entity117 use were more prevalent in peptic @entity1066 and colonic diverticular @entity548 respectively. CONCLUSIONS: From 1996 to 2005, hospitalisations due to peptic @entity1066 and perforation have decreased significantly, whereas the number of cases of @entity694 have increased.
