[One year follow-up study of the recovery of XXXX induced by formulated herb drugs].

@entity4545 @entity1887 @entity701
Previous studies have found that taking formulated herb drugs may reduce the serum @entity701 level which may result in an @entity1887 . We suspect that this effect is induced by corticosteroids artificially mixed in formulated herb drugs. The objectives of this study were to determine the time course of serum @entity701 and plasma @entity4545 ( @entity4545 ) levels, and whether pituitary-adrenal function recovers after quitting formulated herb drugs for a period of one year. Forty eight subjects with an initial serum @entity701 level smaller than 10.7 micrograms/dL due to the intake of formulated herb drugs were recruited. They were tested for serum @entity701 and plasma @entity4545 levels at 08:00 6, 9 and 12 months after quitting formulated herb drugs, respectively. The diagnosis of @entity1887 was confirmed by an @entity4545 test at 9 months and 12 months after quitting the formulated herb drugs. The follow-up rates ranged from 63% to 71%. The 08:00 serum @entity701 levels at the initial test, 6 months, 9 months, and 12 months were 4.4 +/- 0.5 micrograms/dL, 6.6 +/- 0.8 micrograms/dL, 6.6 +/- 0.7 micrograms/dL, 6.2 +/- 0.8 micrograms/dL, respectively, (interpersonal p = 0.0001, intrapersonal p = 0.0004, repeated measures ANOVA test.) The 08:00 plasma @entity4545 levels at the initial test, 6 months, 9 months and 12 months were 33.8 +/- 6.4 pg/mL, 67.6 +/- 16.8 pg/mL, 21.0 +/- 3.2 pg/mL, 16.3 +/- 2.2 pg/mL, respectively (interpersonal P = 0.0001, intrapersonal P = 0.0003, repeated measures ANOVA test.) The statistical significance was the same after logarithmic transformation of the @entity4545 levels.(ABSTRACT TRUNCATED AT 250 WORDS)
