Trends in incidence of XXXX in Denmark 1978-2006.

@entity43 @entity1 @entity5
OBJECTIVE: To examine period-, age- and histology-specific trends in the incidence rate of @entity43 in Denmark in 1978-2006. DESIGN: Register-based cohort study. SETTING: Denmark 1978-2006. POPULATION: 5079 @entity1 diagnosed with @entity43 in at least one of two nationwide registries (4312 @entity5 and 767 non-epithelial/unspecified @entity5 ). METHODS: Estimation of overall incidence rates and period-, age- and histology-specific incidence rates. Age-adjustment was done using the World Standard POPULATION. To evaluate incidence trends over time, we estimated average annual percentage change and 95% confidence intervals (CI) using log-linear Poisson models. MAIN OUTCOME MEASURES: Age-standardized and age-specific incidence rates and average annual percentage change. RESULTS: The incidence of @entity43 increased from 2.6 to 5.5 per 100,000 @entity1 -years between 1978 and 2006, with an average annual percentage change of 2.6% (95% CI: 2.2-3.0). The median age at diagnosis was 52 years. @entity1 40 years or older had a higher average annual percentage change than @entity1 younger than 40 years. @entity5 were mucinous (49.9%) and @entity5 (44.4%). @entity1 with @entity5 were younger at diagnosis (50 years) compared with @entity1 with @entity5 (53 years). @entity1 with @entity5 had a higher average annual percentage incidence change than @entity1 with @entity5 . CONCLUSIONS: The incidence rate of @entity43 increased significantly in Denmark in 1978-2006. In line with results for @entity43 , Denmark had a higher incidence rate of @entity43 compared with the other Nordic countries in 1978-2006.
