XXXX and the risk of early and late mortality after coronary artery bypass graft surgery.

@entity1 @entity28 @entity548 @entity2737 @entity204
BACKGROUND: @entity28 is often considered to be a significant risk factor for postoperative mortality when selecting candidates for coronary artery bypass grafting (CABG). METHODS: We included all @entity1 undergoing a first isolated CABG at the Karolinska Hospital in Stockholm, Sweden, between 1980 and 1995 (n = 6728). @entity1 were categorized on the basis of body mass index (BMI): non-overweight (BMI <25 kg/m2), overweight (25 kg/m2 < or = BMI <30 kg/m2), and @entity28 (BMI > or =30 kg/m2). Multivariate Cox regression was used to assess the risk of re-operation for @entity548 , @entity2737 , and early (< or =30 days) and late (< or =5 years) mortality rates. RESULTS: The average length of follow-up was 6.5 years. There were 252 re-operations for @entity548 , 53 deep sternal wound infections, and 628 @entity204 . @entity1 who were @entity28 had a significantly lower risk of re-operation for @entity548 (risk ratio [RR], 0.32; 95% CI, 0.19-0.53), but a greater risk of @entity2737 (RR, 2.66; 95% CI, 1.21-5.88) compared with @entity1 who were not overweight. However, @entity1 who were @entity28 and @entity1 who were not overweight experienced similar 30-day (RR, 0.65; 95% CI, 0.34-1.27), 1-year (RR, 0.56; 95% CI, 0.29-1.10), and 5-year mortality rates (RR, 0.91; 95% CI, 0.66-1.25). Results for @entity1 who were overweight were consistent with those of @entity1 who were @entity28 . CONCLUSION: @entity1 who are @entity28 are not at a greater risk of early and late mortality after CABG compared with @entity1 who are not overweight, although they appear to have a lower risk of re-operation for @entity548 and a greater risk of @entity2737 . Therefore, obesity per se is not a contraindication for CABG.
