Efficacy of multimodal analgesia injection combined with corticosteroids after XXXX cuff repair.

@entity1 @entity1667 @entity37978 @entity1342 @entity281 @entity272 @entity52910 @entity1286 @entity158 @entity717 @entity282 @entity3661
INTRODUCTION: Although @entity717 cuff repair is minimally invasive, there is still considerable @entity282 , especially during the first 48hours. The present study assessed the short-term efficacy and safety of @entity3661 ( @entity3661 ) injection associated to corticosteroids in @entity717 cuff tear surgery. MATERIAL AND METHOD: A single-center prospective randomized study included 50 @entity1 undergoing @entity717 cuff tear surgery. The study group received subacromial injection of a mixture of @entity1286 , @entity1342 and @entity1667 associated to intra-articular injection of @entity1286 plus @entity1667 ; the control group received only isotonic saline. All @entity1 had had 24hours self-administered @entity1286 associated to standard analgesia. Postoperative data were recorded at 30minutes and 1, 2, 4, 6, 12, 18 and 24hours: @entity158 intensity, @entity1286 intake and side effects, and also time to first @entity1286 bolus and additional analgesic intake. Constant, ASES and SST functional scores were recorded at 3 months. RESULTS: @entity282 was significantly less intense in the @entity3661 group than in controls at 30min, H1, H4, H6, @entity37978 , @entity52910 and H24 (P<0.05). A rebound at D10 occurred in both groups. During the first 24hours, @entity3661 significantly reduced cumulative resort to @entity1286 (P<0.05 at H1/2, P<0.001 at H1-24). Mean time to first bolus was significantly longer in the @entity3661 group (71.6 vs. 33min; P<0.05). The rate of opioid-related side effects was similar between groups. At last follow-up, functional scores were similar between groups. There were no cases of @entity281 or delayed @entity272 . CONCLUSION: @entity3661 associated to corticosteroids after @entity717 cuff tear surgery provided immediate benefit in terms of analgesia and @entity1286 sparing, without apparent risk of @entity281 . The practice is presently little known in France and deserves longer-term assessment, especially as regards functional rehabilitation and tendon healing. LEVEL OF EVIDENCE: 2.
