Influence of wound scores and microbiology on the outcome of the XXXX .

@entity1 @entity3256 @entity2176 @entity6 @entity5176 @entity4034 @entity794 @entity3524 @entity526 @entity1851
AIMS: To establish if the microbiology and the TEXAS, PEDIS and Wagner wound classifications of the @entity6 ( @entity6 ) predict amputation. METHODS: Prospective cohort study of 250 @entity1 with @entity6 from 2009 to 2013. Tissue samples for culture were obtained and wound classification scores were recorded at admission. RESULTS: Infection was monomicrobial in 131 @entity1 (52%). @entity794 was the most frequent pathogen (76 @entity1 , 30%); being @entity3256 -resistant @entity794 in 26% (20/76) @entity526 and Enterobacter faecalis were 2nd and 3rd most frequent pathogens. Two hundred nine @entity1 (85%) needed amputation being major in 25 @entity1 (10%). The three wound scales associated minor amputation but did not predict this outcome. Predictors of minor amputation in the multivariate analysis were the presence of @entity4034 , the location of the wound in the forefoot and of major amputation elevated @entity1851 ( @entity1851 ) levels. A low ankle-brachial index (ABI) predicted major amputation in the follow-up. Overall, 74% of gram-positives were sensitive to @entity5176 and 98% to @entity2176 and 90% of gram-negatives to @entity3524 and 95% to carbapenems. CONCLUSIONS: The presence of @entity4034 and the location of the wound in the forefoot predict minor amputation and elevated @entity1851 levels predict major amputation. In the follow-up a low ABI predicts major amputation.
