Oral XXXX : from the pathological viewpoint.

@entity1496 @entity2735 @entity75 @entity5 @entity957 @entity189 @entity5436 @entity2784 @entity1141
Under the widely used World Health Organization (WHO) classification for the pathological diagnosis of oral @entity75 , @entity1141 , which is graded as mild, moderate or severe, and @entity2735 ( @entity2735 ), which is a @entity189 , are classified as precursor lesions of @entity957 . Since the first edition (Wahi et al. International histological classification of @entity5 no. 4, WHO, Geneva, 1971), the criterion for @entity2735 --that all epithelial layers are replaced by atypical cells--has remained unchanged. However, this @entity189 sequence theory was introduced from the viewpoint of pathological changes in the uterine cervix: in contrast, almost all @entity75 and @entity2735 of the oral mucosa show superficial maturation and differentiation. Based on this recognition, the @entity2784 ( @entity2784 ) classification and Ljubljana classification were included in WHO's latest edition published in 2005. Although the WHO classification is commonly used in Japan, recent developments in oral oncology have promoted modifications of the classification used in this country. In 2005, the Working Group of the Japan Society for @entity5 advocated @entity1496 staining and proposed a modified @entity2784 system, and in 2007, the Working Committee of the Japanese Society for Oral Pathology (JSOP) reported a new @entity2735 (JSOP) definition that included differentiated-type @entity2735 . In 2010, based on these studies, a new entity--oral @entity5436 (OIN)--was included in the first edition of General Rules for Clinical and Pathological Studies on @entity5 . In this review, we focus on the OIN/ @entity2735 (JSOP) new classification of @entity75 in oral mucosa, which further advances the concept of @entity2784 .
