Cardiovascular risk profile and use of XXXX at the age of 70 years: a comparison of two Finnish birth cohorts born 20 years apart.

@entity1 @entity3657 @entity301 @entity65 @entity6817
OBJECTIVE: to compare @entity65 and risk factor profiles of two 70-year-old cohorts of Finns examined in 1991 and 2011 and to describe prevalence of statin use according to cardiovascular risk in the later cohort. METHODS: 1920-born cohort of community-dwelling 70-year-old @entity1 (n = 1032) participated in comprehensive health surveys, physical and laboratory examinations in the Turku Elderly Study (TUVA) during 1991-92. In 2011, identical examination pattern was performed, in a 1940-born cohort of 70-year-old @entity1 (n = 956) from the same area. Prevalence of @entity65 ( @entity65 ) and risk factors in the two cohorts was compared. Further, each cohort was divided into three cardiovascular risk groups (high, moderate and low) based on their estimated risk. Prevalence of statin use was calculated among each risk group in the 1940 cohort. RESULTS: @entity301 (25 versus 11%) and @entity3657 (9 versus 2%) were more common in the 1920 than 1940 cohort, respectively. Lipid profile was worse and blood pressure higher in the earlier cohort, whereas use of @entity6817 and antihypertensives was more common in the later cohort. Forty-two per cent of the 1920 cohort and 29% of the 1940 cohort were estimated to have high cardiovascular risk. In the 1940 cohort, a total of 36% used @entity6817 . Statin use was most common among high-risk @entity1 . CONCLUSIONS: seventy-year olds examined in 2011 had less @entity65 morbidity than their counterparts 20 years earlier, and their cardiovascular risk factors were better controlled which is reflected in higher use of preventive medications, such as @entity6817 and antihypertensives.
