Living-donor liver transplantation for XXXX .

@entity1 @entity5 @entity260 @entity3 @entity157
In cadaveric liver transplantation, the Milan criteria have been accepted as the selection criteria for @entity157 ( @entity157 ) @entity1 in considering organ allocation. However, the situation is different in living-donor liver transplantation (LDLT), in which the donor has a strong preference for altruism. The authors describe herein their experience with LDLT for @entity157 @entity1 using their @entity1 selection criteria. From February 1999 to March 2002, right lobe LDLT was performed in 56 @entity1 with @entity157 . The authors' exclusion criteria included only those with extrahepatic @entity3 or vascular invasion detected during preoperative evaluation. Thirty @entity1 (54%) were in @entity5 , node, @entity3 stage IVa and 25 @entity1 (45%) did not meet the Milan criteria at the time of LDLT. The follow-up period was 1 to 39 months (median, 11 months). The overall survival rates at 1 and 3 years were 73% and 55%, respectively, and the latter was significantly lower than that of adult right lobe LDLT without @entity157 (71% at 3 years). Fourteen @entity1 died because of @entity260 without @entity5 recurrence. Thirty-six @entity1 survived without recurrence and six @entity1 had recurrence. Among the six @entity1 with recurrence, four had survived for 11 to 36 months after LDLT. In the analysis of @entity1 who survived longer than 3 months after transplantation, 19 of 20 within the Milan criteria survived without recurrence. However, 15 of 20 @entity1 beyond the criteria also survived without recurrence for 3 to 33 months (median, 12 months) and three of five @entity1 with recurrence were alive for 11 to 36 months (median, 20 months). Histopathologic grading and microscopic portal venous invasion had significant negative impact on @entity5 recurrence. LDLT was an effective treatment for uncontrollable @entity157 . Because many @entity1 who did not meet the Milan criteria survived without @entity5 recurrence after transplantation, different @entity1 selection criteria are necessary in LDLT to save those with advanced @entity157 .
