Impact of the model C and @entity262 on gamma knife radiosurgery: an evaluation in XXXX .

@entity1 @entity5513 @entity262 @entity5
OBJECT: The technical advances associated with the model C gamma knife include a robotized system enabling automatic positioning of the stereotactic coordinates. The purpose of this study was to analyze the clinical impact of this technical modification. METHODS: The authors studied a sample of @entity1 with @entity5513 ( @entity5513 ). This sample included three groups treated using gamma knife radiosurgery. Group I comprised 21 @entity1 with @entity5513 treated just before the installation of the @entity262 ( @entity262 ). Group II included @entity1 in Group I with new dose plans created using the @entity262 (in other words, simulated dose plans). Group III consisted of a control group of 20 @entity1 matched for @entity5 grade with the previous group and treated recently with the @entity262 . Treatment times were calculated after correcting the time for each shot according to the age of the sources after reloading. The treatment times, including total time, irradiation time, and duration of the neurosurgical procedure, were analyzed. In addition, dose planning including number of isocenters, number of different collimators, malfunctions, and the conformity and selectivity indices were recorded. The trend was to reduce the mean number of collimator runs from 7.9 to 1.2 and to increase the mean number of shots from 7.9 to 15.6, mostly by using the 4-mm collimator exclusively. The @entity262 -related conformity and selectivity were improved from 95 to 97% and from 78 to 84%, respectively. The total treatment time was reduced by 53%, and time required to interact with the @entity1 in the room was considerably reduced (75%), giving the neurosurgeon greater freedom to perform other tasks during the treatment period. The reduction of the time spent by the neurosurgeon at work in the room was 84%. The total radiation time was increased by 54%. CONCLUSIONS: The preliminary results of this study indicate that the robotization of the gamma knife is likely a major advance in radiosurgery.
