Binarization of enhanced depth imaging optical coherence tomographic images of an eye with XXXX : a case report.

@entity1 @entity2479 @entity40271 @entity1829 @entity3193
BACKGROUND: To report a thicker choroid and larger choroidal luminal area in an eye with @entity40271 . To the best of our knowledge, this is the first report demonstrating an increase in the @entity3193 in a case of @entity40271 . In addition, we report the changing appearance of @entity2479 over a 16-year period. CASE PRESENTATION: A 27-year-old @entity1 , who was diagnosed with @entity40271 at age 11  years, visited our clinic. Her best-corrected visual acuity was 20/12.5 in the right eye and light perception in the left eye. Severely dilated, tortuous vascular loops were distributed from the optic disc over all four quadrants of the left fundus. The vascular loops in some areas were more dilated and tortuous than 16  years earlier. Optical coherence tomography (OCT) showed @entity1829 with @entity3193 in the left eye. The subfoveal choroidal thickness was manually measured by the caliper function in the enhanced depth imaging OCT (EDI-OCT) images. Binarization of the EDI-OCT images was performed with publicly accessible ImageJ software. The examined area of the subfoveal choroid was 1,500   m wide, and the dark areas representing the luminal areas were traced by the Niblack method. After determining the distance of each pixel, the luminal area was automatically calculated. The subfoveal choroidal thickness was 250   m in the right eye and 462   m in the left eye. The luminal area of the 1,500- m-wide subfoveal choroid was computed to be 307,165.6   m(2) in the right eye and 545,780.7   m(2) in the left eye. CONCLUSIONS: The EDI-OCT images showed a thicker choroid, and binarization of the EDI-OCT images showed that the luminal areas were significantly larger in the affected eye, suggesting a dilatation of the choroidal vessels. The results demonstrated that conversion of EDI-OCT images to binary images was a useful method to quantify the @entity3193 .
