Relationship between nuclear morphometry, DNA content and resectability of XXXX .

@entity1 @entity788 @entity5 @entity20168 @entity982
AIM: To investigate the association of nuclear morphometry and DNA content with resectability of @entity788 . METHODS: A total of 36 @entity1 with @entity788 were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of @entity5 cells were analyzed by IBAS autoimagine analyzer from @entity982 -embedded materials. Localization size, histological type and grade, and clinical stage of the @entity5 were evaluated. Factors influencing resectability of @entity788 were investigated using stepwise regression analysis. RESULTS: Statistical significance was found in nuclear DNA content (integrated optical density, IOD) of @entity5 cells (1.64+/-0.41 vs 2.96+/-0.55), DNA ploidy, ages (46.5+/-5.3 years vs 58.6+/-0.7 years) and @entity5 volumes (298.1+/-101.5 cm(3) vs 634.7+/-512.5 cm(3)) in both groups (P<0.05), and no difference was found in the nuclear morphometry (P>0.05). The rates of diploid/tetraploid and aneuploid were 66.7 % and 33.3 % in resectable group respectively, and 38.9 % and 62.1 % in unresectable group, respectively (P<0.05). IOD (X(12)), ploidy status (X(12)) and clinical stage ( @entity20168 ) were radical resectable indicators with statistical significance. The regression equation for resectability was Y=-9.2053+3.5428X(12)+2.5390X(13)-2.3001X(3) (RR=0.8780, P<0.01). CONCLUSION: There is a high correlation between resectability of @entity788 and their DNA contents, DNA ploidy status and clinical stage.
