Increasing @entity64 incidence and decreasing case fatality, 1989-1998: a study from the XXXX register in Malm  , Sweden.

@entity1 @entity583 @entity64
BACKGROUND AND PURPOSE: Although the incidence of and mortality from @entity583 ( @entity583 ) have declined in most industrialized countries, incidence studies of @entity64 have shown less consistent trends. This study examines time trends in the incidence of @entity64 and case fatality rates in relation to socioeconomic circumstances and history of @entity583 . METHODS: @entity64 incidence in the city of Malm  , Sweden (250,000 citizens), has been continuously monitored since 1989. All @entity1 50 to 79 years of age who experienced a first-ever @entity64 between 1989 and 1998 were included. RESULTS: We included 3621 @entity1 (1969 @entity1 , 1652 @entity1 ). The age-standardized incidence was 647 per 100,000 @entity1 -years for @entity1 and 400 per 100,000 @entity1 -years for @entity1 . The annual increase-3.1% in @entity1 (P<0.05) and 2.9% in @entity1 (P<0.05)-was more pronounced in the younger age groups and was lowest in areas with poor socioeconomic circumstances. We found that 13% of the @entity1 and 6% of the @entity1 had a history of @entity583 ; this proportion was stable over the study period. The average case fatality rates in 1989 to 1998 were 10% for @entity1 and 9.3% for @entity1 . Rates remained stable for @entity1 but declined significantly in @entity1 (odds ratio per year, 0.895; 95% confidence interval, 0.84 to 0.95). CONCLUSIONS: In this urban population, @entity64 incidence increased between 1989 and 1998. The rate of increase tended to be lower in residential areas with least favorable socioeconomic circumstances. The proportion with a history of @entity583 remained unchanged during the study period. There has been significant improvement in the case fatality rate in @entity1 but not in @entity1 .
