Pediatric XXXX : a retrospective series.

@entity1 @entity41 @entity428 @entity5 @entity16 @entity7667
OBJECT: The aim of this study was to retrospectively review the clinical presentation, the roles of surgery and adjuvant therapy, and the treatment-related morbidity in @entity1 with a @entity7667 in the posterior fossa and to try and determine the prognostic factors. METHODS: Between 1991 and 2006, 10 @entity1 were treated for a posterior fossa @entity7667 at the authors' institution. The mean age of the @entity1 , the duration of symptoms prior to diagnosis, and the follow-up were 8.2, 2.4, and 3.9 years, respectively. Nine of the @entity1 presented with symptoms of @entity428 . Preoperative imaging showed enhancement in all @entity1 ; in eight it was in a patchy distribution. The operations consisted of radical resection (> 75%) in seven @entity1 , biopsy in two, and a total macroscopic excision in one. RESULTS: The surgical procedure did not cause deterioration in the @entity16 in any of the @entity1 . There was no recurrence in the @entity1 who underwent total macroscopic excision of the @entity5 , and there has been no @entity5 progression in three @entity1 , two of whom have had no evidence of enhancement of the postoperative @entity41 . The @entity5 has progressed in six @entity1 , requiring further surgery in three, chemotherapy in four, and radiotherapy and second-line chemotherapy in one @entity1 to control the @entity5 . CONCLUSIONS: The imaging of @entity7667 in the posterior fossa showed patchy enhancement. The @entity1 in whom it was possible to achieve a radical resection, aimed at removing at least the enhancing portion of the @entity5 , have not required further treatment. A second excision, for progressive @entity5 , is an effective adjuvant therapy.
