Fertility of young mares after long-term anabolic XXXX treatment.

@entity146 @entity5420 @entity134 @entity11330 @entity230 @entity21668 @entity72450
The effect of prior treatment with @entity21668 was studied in 46 three-year-old mares. In the preceding year, these mares had been assigned to 1 of 4 treatment groups and had received the manufacturer's recommended dosage of 1.1 mg of @entity72450 (BU)/kg of body weight, 4.4 mg of @entity72450 (4 BU)/kg, 1.1 mg of @entity11330 (ND)/kg, or 0.04 ml of @entity5420 oil/kg (control, C). Mares had received an injection every 3 weeks for 54 weeks for a total of 19 injections, with the final injection in December. In the following breeding season, fewer (P less than 0.05) mares in all groups previously administered @entity21668 displayed @entity146 than did mares in the control group. Duration of estrus was shortened (P less than 0.05) in mares that had received @entity230 . Abnormal sexual behavior that was observed during @entity134 treatment continued (P less than 0.05) for up to 6 months after treatment ceased. However, observations of @entity146 declined with time (P less than 0.05). All mares in each treatment group ovulated by the end of the trial, and the interval to first ovulation was similar (P greater than 0.05). Ovarian size, follicular development, and conditions of the tubular genitalia was adversely (P less than 0.05) affected in mares in all @entity134 -treatment groups until approximately the middle of March. After that time, no difference was noted among groups. First-cycle pregnancy rates were 83%, 67%, 50%, and 42% for mares in the untreated, BU, 4 BU, and ND groups, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
