Initial experience using microwave ablation therapy for XXXX treatment: 18-month follow-up.

@entity1 @entity5 @entity703
OBJECTIVES: To assess efficacy and morbidity of microwave ablation (MWA) for small @entity703 in an initial cohort of @entity1 . MWA is a recently introduced thermal needle ablation treatment modality with theoretical advantages compared with radiofrequency ablation, such as greater intratumoral temperatures, lack of a grounding pad, and superior convection profile. However, experience has been limited in the @entity1 kidney. METHODS: Ten @entity1 with a single, solid-enhancing @entity703 from June 2008 to November 2008 received laparoscopic or computed tomography-guided percutaneous MWA at a tertiary referral center with >= 14 months of follow-up. MWA was performed using the Valleylab Evident, 915-MHz MWA system at 45 W with intraoperative biopsy before ablation, and peripheral fiberoptic thermometry to determine the treatment endpoints. The @entity1 were followed up with contrast-enhanced computed tomography at 1 month, 6 months to 1 year, and annually to monitor for @entity5 recurrence. RESULTS: The follow-up duration for the 6 male and 4 female @entity1 (mean @entity5 size 3.65 cm, range 2.0-5.5; mean age 69.8 years) was 17.9 months. The recurrence rate, defined by persistent enhancement, was 38% (3 of 8). The intraoperative and postoperative complication rate was 20% and 40%, respectively. CONCLUSIONS: MWA resulted in poor oncologic outcomes with a significant complication rate at an intermediate level of follow-up. However, MWA has promising theoretical advantages and should not be discarded. Additional studies should be considered to better understand the microwave-tissue interaction and treatment endpoints for different size renal masses before widespread use.
