Ambulatory scintigraphic assessment of transient changes in left ventricular function: a new method for detection of silent XXXX .

@entity662 @entity1 @entity1136 @entity296 @entity308 @entity409 @entity1459 @entity453 @entity1002
Demonstration of @entity1002 in the absence of @entity662 should provide important confirmation of silent @entity296 in @entity1 with asymptomatic ST segment changes. For this purpose, a new portable scintillation probe (VEST) similar to a miniaturized nuclear stethoscope combined with a Holter ECG was evaluated. After standard equilibrium radionuclide angiocardiography with @entity1136 labelled red blood cells, the VEST was positioned under gamma-camera control and data were recorded from 1-12 h in 61 unselected @entity1 . Ejection fraction (LVEF), relative changes in volumes, heart rate and ST segment changes were determined. Reproducibility of LVEF at rest (r = 0.91; variability 3.8 +/- 3%, N = 19) and during exercise (r = 0.98; variability 3.2 +/- 2%, N = 19) was good. In 15 asymptomatic exercise tests four different patterns of LVEF and ST segment responses were identified: (1) decrease in LVEF followed by significant ST @entity308 (five times); (2) ST @entity308 followed by decrease in LVEF (three times); (3) decrease in LVEF without significant ST changes (three times); and (4) ST @entity308 without significant LVEF change (four times). In this still small series, patterns (1) to (3) corresponded to @entity1 with documented @entity453 , which was not the case for pattern (4). For detection of silent ischaemia at rest, a decrease in LVEF of greater than 5% lasting for greater than 1 min was defined as @entity409 . Using this definition, four spontaneous episodes of silent @entity409 could be demonstrated in two of three CCU @entity1 with @entity1459 during 160-680 min of data recordings without simultaneous ST changes.(ABSTRACT TRUNCATED AT 250 WORDS)
