Evolution of gender-related differences in outcomes from two decades of XXXX repair.

@entity1 @entity449 @entity1070 @entity439 @entity299 @entity1029
OBJECTIVE: @entity1 have been under-represented in trials that set guidelines for the management of @entity449 . Several studies reported inferior outcomes in @entity1 compared with @entity1 after @entity439 repair (EVAR). We investigated the relationship between gender and outcomes after EVAR. METHODS: A total of 1380 consecutive @entity1 underwent elective EVAR from 1992 to 2012. Baseline, intraoperative, and postoperative variables by gender were analyzed from a prospective database. RESULTS: The cohort comprised 214 @entity1 (15.5%) and 1166 @entity1 (84.5%). @entity1 were older than @entity1 at repair (77.8 vs 74.5  years, P  < .001) and had less @entity299 (P  = .005). They had shorter (19.8     12.9 vs 26.3     14.7  mm; P  < .001) more angulated aortic necks (38.8       16.1   vs 31.2       14.7  ; P  < .001) and fewer @entity1029 (P  = .002). @entity1 had more arterial reconstructions (iliac conduits, P  = .006; thrombolysis and thrombectomy, P  = .013; patch angioplasty, P  < .001; endarterectomy, P  < .001), more perioperative complications (16.9% vs 9.1%; P  = .001), and more in-hospital days (4.1 vs 3.4  days; P  = .029). Perioperative mortality was equivalent ( @entity1 : 2% vs @entity1 : 2.3%; P  = .73). Mean follow-up was 30.9  months. @entity1 and @entity1 experienced equivalent @entity439 -related deaths and overall survival. Survival curve analysis showed @entity1070 were more likely to develop in @entity1 than @entity1 (P  = .005); however, there was no difference in rates of arterial reinterventions required for each gender during the follow-up period. CONCLUSIONS: Female gender is associated with more periprocedural complications, adjunctive arterial procedures, and increased @entity1070 but does not affect long-term reinterventions or survival. Further studies are warranted to elucidate the effect of gender on outcomes. These data should be considered when selecting EVAR for @entity1 and @entity1 .
