[Repeat renal biopsy in XXXX : report of a case].

@entity1 @entity9538 @entity404 @entity1596 @entity2262 @entity1986 @entity32117 @entity617
A Japanese @entity1 aged 12 years who presented with a month history of @entity1596 developed a significant elevation of urinary @entity2262 ( @entity2262 ) up to 13,933 micrograms/l. A percutaneous renal biopsy revealed a dense @entity404 -positive T-cell infiltration with focal @entity9538 in the interstitium. The tubulointerstitial score (TI score) described by Foster et al. was 7 points. She was diagnosed as having @entity32117 ( @entity32117 ). Due to the severe @entity1986 , a 6-month course of @entity617 at the dose of 30 mg per alternate day was started. The levels of urinary @entity2262 dramatically decreased following treatment and the renal function remained normal. The second renal biopsy performed 6 months later revealed mild persistent @entity404 -positive T-cell infiltration associated with 19% periglomerular thickening, with the TI score of 4 points. These clinical observations suggest that the interstitial cell infiltration persists for a relatively long time in a proportion of @entity1 with @entity32117 . Since persistent @entity1986 has been known to be harmful to the kidney, we therefore speculate that prompt administration of corticosteroids might be beneficial to these @entity1 . Although the renal outcome of @entity32117 has been reported to be favorable to date, @entity1 with severe @entity1986 should be followed under close observation. Study of similar @entity1 is needed to clarify our understanding of effective therapy for @entity32117 .
