Echocardiographic Strain and Mortality in Black Americans With XXXX on Hemodialysis.

@entity1 @entity407 @entity712 @entity101 @entity6 @entity301 @entity6475 @entity65 @entity1002 @entity454
UNASSIGNED: @entity454 ( @entity454 ) presents a significant health burden and is associated with high @entity65 and mortality. This is particularly true in African Americans who generally have higher rates of @entity65 . Outcomes in @entity454 are related to extent of @entity65 , but markers for outcome are not clearly established. @entity6475 ( @entity6475 ) has emerged as an important measure of left ventricular systolic function that is additive to traditional ejection fraction (EF). It can be measured on routine digital echocardiography and is reproducible. This study tested the hypothesis that @entity6475 is associated with mortality in black Americans with @entity454 and preserved EF. Forty-eight outpatients undergoing hemodialysis, 59.4    13.3  years, with EF >= 50% were prospectively enrolled. @entity6475 , measured by an offline speckle tracking algorithm, ranged from  -8.6% to  -22.0% with a mean of  -13.4%, substantially below normal (-16% or more negative). The prevalence of @entity1002 , as determined by @entity6475 , was 89%. @entity1 were followed for an average of 1.9  years; all-cause mortality was 19% (9 deaths). @entity6475 was significantly associated with mortality (hazard ratio 1.15, 95% confidence interval 1.02 to 1.30, p  = 0.02), whereas EF was not. After adjustment for multiple potential confounders (age, gender, race, smoking, @entity101 , @entity6 , @entity407 , @entity301 , @entity712 , and EF), @entity6475 remained strongly associated with mortality (hazard ratio 1.30, 95% confidence interval 1.10 to 1.56, p  = 0.002). In  conclusion, @entity6475 is an important index in @entity1 with @entity454 , which is additive to EF as a marker for mortality in this high-risk group.
