Quality of life in nonorganic and XXXX : I. Comparison with normative data.

@entity1 @entity2147 @entity22 @entity1316 @entity148 @entity35 @entity25 @entity386
Subjective health-related quality of life (HRQoL) was investigated in 100 @entity1 with disturbed sleep (39 @entity1 aged 52 +/- 13 years and 61 @entity1 aged 53 +/- 10 years) referred to the sleep laboratory and compared with HRQoL in 100 normal healthy adults. Measurements included the Quality of Life Index (QLI) (Mezzich and Cohen), and objective (polysomnographic) and subjective (psychometric) quality of sleep and awakening. Statistical analysis (Mann-Whitney U-test) showed HRQoL to be significantly reduced in @entity25 ( @entity25 ), with a more pronounced reduction in nonorganic than in organic @entity25 . @entity1 with @entity2147 were more disturbed than those with @entity22 . Within organic @entity25 , @entity1 with @entity386 were more disturbed than those with obstructive snoring. Out of ten elementary HRQoL components, seven were disturbed in @entity25 : physical well-being, psychological well-being, self-care and independent functioning, occupational functioning, interpersonal functioning, personal fulfillment, and overall quality of life. No differences between @entity1 and normal healthy subjects where found in the components social support, community and services support or spiritual fulfillment. @entity1 suffering from nonorganic @entity25 had significantly worse scores in physical and psychological well-being and overall quality of life than those with organic @entity25 . @entity1 with both @entity25 and additional diagnoses of @entity1316 had more profoundly reduced HRQoL than those with @entity148 . Follow-up of 51 @entity1 (31 with nonorganic @entity25 and 20 with organic @entity25 ) one year after sleep laboratory investigation and subsequent treatment found significantly improved HRQoL compared with pre-treatment. Moreover, @entity1 diagnosed and treated in the sleep laboratory showed lower re-hospitalization @entity35 .
