XXXX with a deceptive pattern of spread to the uterine cervix: a manifestation of @entity1204 liable to be misinterpreted as an independent carcinoma or a benign lesion.

@entity1204 @entity1 @entity172 @entity2785 @entity5 @entity75 @entity1373 @entity854
The prognosis of @entity1204 is determined in part by stage; endocervical stromal involvement (stage IIB) imparts a worsened prognosis. We describe a deceptive pattern of stage IIB disease that mimics a primary @entity2785 and may lead to understaging of @entity1204 . Fifteen cases of @entity1204 with a peculiar pattern of cervical involvement were identified from our consultation files. All cases were referred in consultation because of doubt about the nature of the cervical process and its relation to the @entity5 ; in a few instances, the cervical proliferation was considered possibly benign and in one case was misinterpreted as @entity1373 . The @entity1 ranged from 49 to 84 years in age (mean age 64.9 years). There was usually a grossly evident @entity1204 . The cervix was unremarkable grossly in at least 11 @entity1 . The cervical @entity5 were composed of variably shaped, often tubular glands with little or no stromal response and mainly invaded as widely spaced glands that often appeared deceptively benign. In 14 cases luminal secretions, mainly eosinophilic, were identified, often leading to consideration of a @entity75 . Ten of the @entity1204 were grade 1, four grade 2, and one grade 3. One was noninvasive, nine superficially invasive, and five deeply invasive. In four cases myoinvasion had, at least in part, a diffusely infiltrative pattern. The @entity5 in the cervix showed no in situ component and no definite surface involvement. Continuity with the @entity5 could be demonstrated in 12 cases. Ten of the cervical @entity5 invaded more deeply than the @entity1204 , four invaded to a similar depth, and only one was more superficial than its endometrial counterpart. The cervical and @entity5 had a similar immunoprofile in nine cases: all were vimentin positive, eight @entity172 positive and one negative, four carcinoembryonic antigen negative, and five with focal apical or rare cytoplasmic staining. This immunoprofile in conjunction with routine morphologic similarity between the two @entity5 and the usual documented continuity between them indicate that the cervical process represents spread from the @entity1204 . It is important for both therapeutic and prognostic reasons that the @entity854 is not misinterpreted as a benign or malignant primary endocervical glandular process.
