Focal cortical dysplasias: MR imaging, histopathologic, and clinical correlations in surgically treated @entity1 with XXXX .

@entity1 @entity131 @entity75 @entity854 @entity302 @entity10067 @entity1141
BACKGROUND AND PURPOSE: @entity10067 ( @entity10067 ) covers a spectrum of conditions in which the neuropathologic and electroclinic presentations and the surgical outcomes vary. The aim of this study was to identify the MR features of histologic subtypes of @entity10067 that would be useful for differential diagnosis. METHODS: We reviewed the MR data of 49 @entity1 treated surgically for intractable @entity302 , who received a histologic diagnosis of @entity10067 not associated with other @entity75 except @entity131 and who were classified by histologic criteria as having @entity1141 (28 @entity1 ), @entity1141 (six @entity1 ), or @entity10067 (15 @entity1 ). RESULTS: From the MR features, it was generally possible to distinguish @entity10067 from architectural or @entity1141 (non- @entity10067 ). Findings suggesting @entity10067 were focal cortical thickening, blurring of the gray-white matter junction, and hyperintensity (on T2-weighted images) of subcortical white matter often tapering toward the ventricle. Focal @entity75 with shrinkage and moderate signal intensity alterations in the white matter core were present in most @entity1 with @entity1141 . The lesion was generally extratemporal in @entity10067 and temporal in @entity1141 . Ipsilateral @entity131 was often present in @entity1141 ( @entity854 ). CONCLUSIONS: In @entity1 with @entity10067 , @entity10067 and non- @entity10067 can usually be distinguished with MR imaging, although some overlap exists. A provisional MR diagnosis is important for presurgical investigations and surgical planning and may have prognostic implications.
