Regional cerebral blood flow and cytokines in young females with XXXX .

@entity1 @entity650 @entity308 @entity239 @entity1356 @entity13278 @entity2902 @entity1199 @entity687 @entity25 @entity13279 @entity2693
OBJECTIVE: To determine whether there is any difference in regional cerebral blood flow ( @entity13279 ) and serum cytokine levels and association between clinical parameters and @entity13279 and serum cytokine levels in young females with @entity239 ( @entity239 ). The other aim was to search whether the @entity308 state has any effect on these two parameters. METHODS: Nineteen @entity1 with @entity239 and 20 healthy @entity1 had 99mTc-HMPAO brain single-photon-emission computed tomography (SPECT) to evaluate @entity13279 . Serum interleukin (IL) levels ( @entity1356 , @entity2902 , @entity650 and @entity687 ) were measured. Clinical and psychological evaluation was also carried out in @entity239 @entity1 and healthy controls. RESULTS: The @entity1 with @entity239 had significantly higher radioactivity uptake ratio in right and left caudate nucleus (p = 0.009, p = 0.001, respectively) than healthy controls. There was statistically significant decrease in the @entity13278 uptake in the right superior parietal (p = 0.041), gyrus rectalis (p = 0.036) and pons (p = 0.023). @entity239 @entity1 had significantly higher serum @entity2902 and @entity687 levels (p = 0.023, p = 0.011, respectively) than controls. Additionally, @entity239 @entity1 had significantly higher @entity239 Impact Questionnaire (FIQ), Health Assessment Questionnaire (HAQ), and @entity308 ( @entity308 ) scores (p = 0.000) than controls. Interestingly, the @entity1 with mild @entity308 or without (i.e. @entity308 -score < or = 16) had significantly higher serum @entity687 levels (p = 0.027) and increased radioactivity uptake ratio in the pons (P = 0.036) than the @entity1 with more severe @entity308 (i.e. @entity308 -score > 16). With regard to regional cerebral blood flow, significant correlations were detected between RSP and morning @entity2693 (r = 0.70, p < 0.01) and @entity25 (r = -0.53, p < 0.05), and between gyrus rectalis and FIQ score. There were significant correlations between LCN and @entity1199 (P = 0.025), between RSP and morning @entity2693 (P = 0.006), @entity25 (P = 0.021) according to multiple regression analysis test. CONCLUSION: This study shows a significant increase in @entity13279 of caudate nuclei, a reduction in the pons, some cortical regions activity and a increase in @entity687 , @entity2902 levels of young female @entity1 with @entity239 . These findings are more prominent in @entity1 with low @entity308 scores.
