@entity935 administration in oliguria and XXXX .

@entity1 @entity935 @entity908 @entity3124 @entity1483 @entity1372 @entity177 @entity17258 @entity1576
@entity177 significanlty worsens the prognosis of many @entity3124 , particularly in @entity1 with @entity1576 . In 52 @entity1 , a continuous infusion of @entity935 , 1.5-2.5 micrograms/kg . min, was administered when @entity908 clearance (Ccr) fell below 40 ml/min and urinary output was less than 1 ml/kg . h despite normal intravascular volume. In 18 @entity1 , a continuous infusion of @entity1483 (3-5 mg/kg . day) was also administered. Daily, two 3-h collections of urine and blood specimens were obtained to determine Ccr, osmolar clearance (Cosm), free water clearance ( @entity17258 ) and excreted fraction of filtered @entity1372 (FENa); one collection was made during @entity935 infusion and one while the infusion was suspended. Cardiac output and pulmonary venous admixture were also measured. The authors obtained 199 urine collections in 52 @entity1 ; considering the aggregate @entity1 pouplation, urinary output increased by 42.3% (30.2 +/- 3.45 (SEM) ml/h), on @entity935 infusion. Cosm, FENa, and Ccr were also higher on @entity935 . @entity17258 and hemodynamic variables were not altered by @entity935 infusion. When @entity1 were startified on the basis of mechanical ventilatory support, Ccr and @entity1483 administration, @entity935 infusion essentially caused the same changes in the variables studied as described for the aggregate @entity1 population. Diuresis and @entity1372 excretion increased significantly on @entity935 even in those @entity1 receiving @entity1483 infusion. The authors conclude that fluid and osmolar load can be eliminated more effectively in @entity3124 @entity1 with continuous infusion of 1.5-2.5 micrograms/kg . min of @entity935 .
