The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of XXXX .

@entity1 @entity8393 @entity8942 @entity591 @entity3257
In 96 cases of @entity8942 , results of chronic pharmacological assessment (CPA) were compared with acute electrophysiological-pharmacologic assessments ( @entity8393 ) to evaluate the usefulness of @entity8393 . I. @entity1 with sustained VT (31 cases): Sustained VT and repetitive ventricular response (RVR) could be induced in 61% and 23% respectively. More than one effective drug was found by @entity8393 for 23 of 24 subjects. Of the 22 followed by CPA, the effectiveness of medication was excellent for 14 (64%), moderate for 1, slight for 4, and ineffective for 3 (14%). II. @entity1 with @entity3257 (23 cases): RVR could be induced in 52%. Effective medication was identified by @entity8393 for 8 of 10 @entity1 . Of the 7 followed by CPA, the effectiveness of medication was excellent for 2(28.5%) moderate for 2, and ineffective for 3. III. @entity1 with PSVT (42 cases): PSVT could be induced in 90% of cases. Effective medication was found for all 31 cases which underwent @entity8393 . Of the 23 cases followed by CPA, the chronic efficacy of drugs was excellent for 7 (30%), moderate for 5 (22%), slight for 7 (30%), and noneffective for 4 (18%). Therefore, we conclude that the usefulness of @entity8393 differs according to the type of @entity591 . @entity8393 is most useful in predicting chronic results for @entity1 with sustained VT, especially when the sustained VT is readily reproducible by electrical stimulation. It is less useful for nonsustained VT and PSVT. With nonsustained VT, @entity8393 is limited by difficulty in repeatedly inducing RVR, and by difficulty in predicting the appropriate medication for chronic oral therapy. With PSVT, even though the PSVT can be induced with greater success, @entity8393 is limited by variations in pharmacologic effects over time, which create discrepancies between @entity8393 and CPA.
