Risk factors for severe XXXX after valve replacement and aortocoronary bypass operations: analysis of 246 cases by logistic regression.

@entity1 @entity295 @entity6 @entity55 @entity548 @entity2348 @entity2737 @entity281 @entity340
Risk factors for severe @entity2348 , that is, @entity2737 , @entity55 , @entity295 , and @entity340 , were evaluated in 246 consecutive @entity1 undergoing valve replacement (N = 84) or aortocoronary bypass operation (N = 162). Multiple logistic regression analysis was applied to determine the ability of putative risk factors to predict @entity281 . The risk factors considered were age, sex, @entity6 , duration of cardiopulmonary bypass (CPB), duration of operation, amount of blood restored on the day of operation, repeat thoracotomy for @entity548 , intraaortic balloon pumping, reoperation, emergency operation, and the professional status of the surgeon. Severe @entity281 occurred in similar frequency after valve replacement (8/84; 9.5%) and aortocoronary bypass (11/162; 6.8%). For @entity1 who had a bypass procedure, repeat thoracotomy was the only factor significantly associated with @entity281 (p = 0.0004). However, the classification analysis revealed that this variable alone is too unspecific for a reliable prediction. Univariate analysis indicated that restoration of more than 2,500 ml of blood (p = 0.0001), reoperation (p = 0.0821), duration of operation (p = 0.0061), duration of CPB (p = 0.0318), and intraaortic balloon pumping (p = 0.0281) were associated with @entity281 following valve replacement. A model with three variables emerged from the multiple logistic regression: after correction for blood restoration, reoperation, and duration of CPB, no other variable was of additional predictive value. For @entity1 who underwent valve replacement, the model performed well in predicting complications. The classification analysis revealed a high correspondence between observed and predicted @entity281 : it correctly predicted 75% of the @entity1 with @entity281 and 96% of those without @entity281 .(ABSTRACT TRUNCATED AT 250 WORDS)
