The effect of Katsura-uri (Japanese pickling @entity2487 , XXXX . conomon) and its derived ingredient @entity71460 on energy metabolism during aerobic exercise.

@entity1 @entity2487 @entity19 @entity26 @entity71460 @entity1735 @entity880 @entity8642 @entity413
PURPOSE: We investigated the effect of Katsura-uri (Japanese pickling @entity2487 ; @entity2487 . conomon) on energy metabolism during exercise in @entity1 and animal studies. METHODS: Eight healthy @entity1 (mean age, 21.4      0.7  years) participated in a single-blind, crossover study. Thirty minutes after ingesting the Katsura-uri drink or placebo drink, they exercised on a cycle ergometer at 40% maximal heart rate for 30  min. Respiratory gas analysis was performed during exercise to examine @entity26 consumption and substrate utilization. Blood biochemical parameters were evaluated during exercise. In the animal study, the effect of @entity71460 ( @entity8642 ), a Katsura-uri derived component was examined in @entity19 . Immediately after running at 25  m/min for 30  min, biochemical parameters in the hind limb muscle and blood of @entity19 were measured. RESULTS: @entity26 consumption during exercise was higher in the Katsura-uri condition (19.8      3.5  mL/kg/min) than the placebo condition (18.6      3.0  mL/kg/min) (P  <  0.05). The elevation of blood @entity880 was lower in the Katsura-uri condition (1.7      0.4  mM) than the placebo condition (2.2      0.6  mM) 15  min after beginning exercise (P  <  0.05). There was a higher positive correlation between @entity880 concentration and @entity1735 oxidation during exercise in the Katsura-uri condition (R(2)  =  0.86) compared to the placebo condition (R(2)  =  0.47). The decrease in intermuscular pH and the increase in blood @entity880 following exercise were prevented by @entity8642 supplementation (250  ppm) with significant differences in the @entity8642 -supplemented group compared to the control group. CONCLUSIONS: These results suggest that the ingestion of Katsura-uri and/or @entity8642 improves @entity413 metabolism and acidification in skeletal muscles during exercise in @entity1 and animal studies.
