Relationship between age and subtypes of XXXX in @entity191 .

@entity1 @entity935 @entity191 @entity1833 @entity716
OBJECTIVE: Psychotic symptoms (PS) in @entity191 ( @entity191 ) usually develop as a side effect of the dopaminergic therapy and consist of @entity1833 and delusions. We observed that @entity191 @entity1 who developed delusions tend to be younger than those with @entity1833 and we aimed to investigate the validity of this observation. METHODS: The medical records of 127 @entity191 @entity1 with PS were reviewed and 76 @entity1 who were on treatment with @entity935 agonists with or without levodopa at the time of developing PS were included. @entity1 were stratified into 3 groups according to the subtypes of PS: @entity1 with solely @entity1833 (n = 46), solely delusions (n = 18), and both types (n = 12). The groups were compared with respect to the age-at-onset of @entity191 and PS, duration of @entity191 , Activities of Daily Living (ADL) and motor subscale scores of Unified @entity191 Rating Scale (UPDRS), and levodopa equivalent dose of the dopaminergic agents administered at the time of PS onset. RESULTS: The mean age-at onset of @entity191 and PS was significantly younger (p = 0.0001) in @entity1 with delusions (49 and 55.9 years) than those with @entity1833 (61.9 and 68.9 years). The same parameters were also significantly different (p = 0.002 and p = 0.001, respectively) between the groups of @entity1 with concurrent delusions and @entity1833 (51.7 and 57.2 years) and those with only @entity1833 . ADL and motor subscale scores were higher in @entity1 with @entity1833 (p = 0.016 and p = 0.013) compared with those noted in @entity1 with delusions despite similar disease duration. The mean levodopa equivalent doses of the dopaminergic agents administered at the time of onset of PS did not differ between the groups. CONCLUSION: This study supported an association of delusions with younger onset of both @entity191 and @entity716 as compared with @entity1833 . However, additional factors related to this association remain to be elucidated.
