GLUCAGON PRESCRIPTION PATTERNS IN XXXX WITH EITHER TYPE 1 OR 2 DIABETES WITH NEWLY PRESCRIBED INSULIN.

@entity1 @entity6 @entity4053
OBJECTIVE: To describe glucagon prescription patterns in @entity1 with type 1 (T1DM) or type 2 @entity6 (T2DM) who received an initial insulin prescription. METHODS: Retrospective analyses were conducted with data from Truven Health MarketScan databases to assess time to glucagon prescriptions: filled within 1.5 months after index date (early) or after 1.5 months postindex (nonearly). The index date was the date of first insulin prescription between January 1, 2009 and December 31, 2011; for T2DM, without an insulin prescription in the previous 6 months; for T1DM, @entity6 diagnosis preindex or within 3 months postindex. RESULTS: Analysis included 8,814 @entity1 with T1DM and 47,051 with T2DM (49.3% and 2.4%, respectively) who had glucagon prescriptions filled. The median times to first glucagon prescription were 196 days (T1DM) and 288 days (T2DM). The rates of filling glucagon were highest in the first 1.5 months. The times to first @entity4053 -related emergency room (ER) visit for T1DM and T2DM cohorts were initially similar for those with early glucagon versus nonearly glucagon prescriptions. After 10.8 and 2.5 months postindex, respectively, the percentage of @entity4053 -related ER visits was lower for those with early glucagon prescriptions. CONCLUSION: Glucagon prescriptions filled for @entity1 with @entity6 who are initiating insulin are low. @entity1 with T1DM who were younger and healthier filled glucagon prescriptions more often; @entity1 with T2DM who were younger and sicker and had a higher percentage of @entity4053 -related ER visit history filled glucagon prescriptions more often. Glucagon filled early was associated with a lower incidence of @entity4053 -related ER visits. ABBREVIATIONS: ADA = American @entity6 Association CCI = Charlson comorbidity index CI = confidence interval ER = emergency room GBM = gradient boosting method HR = hazard ratio KM = Kaplan-Meier NPH = neutral protamine Hagedorn T1DM = type 1 @entity6 T2DM = type 2 @entity6 .
