Adrenoceptors mediating relaxation to XXXX in @entity35 isolated jejunum.

@entity1169 @entity30828 @entity3047 @entity1425 @entity3159 @entity3044 @entity35 @entity2661 @entity1063 @entity4338
1. The characteristics of adrenoceptors mediating relaxation to @entity2661 in @entity35 isolated jejunum were investigated. 2. @entity2661 and @entity3047 produced relaxation of the @entity4338 -contracted strips with an order of potency of @entity3044 (1.0) > @entity3047 (0.63) > @entity1063 (0.1) > @entity1425 (0.04). 3. In the presence of both @entity3159 (1 microM) and @entity1169 (1 microM) only small dextral shifts of the concentration-response curves to agonists were observed and an order of potency of @entity3047 (2.5) > @entity3044 (1.0) > @entity1063 (0.2) > @entity1425 (0.1) was obtained. 4. In the presence of @entity3159 (1 microM) and @entity1169 (1 microM), @entity30828 (0.1-10 microM) produced a concentration-dependent rightward shift of the concentration-response curve to @entity1425 with a Schild slope not significantly different from unity and a mean pA2 value of 7.01. 5. The resistance of relaxant responses to @entity1169 , the relatively high potency of @entity3047 compared to @entity2661 and the competitive antagonism of relaxant responses to @entity1425 by @entity30828 suggest that beta-adrenoceptors in @entity35 small intestine are mainly atypical in nature.
