Iris-fixated phakic intraocular lens implantation to correct XXXX and a predictive model of endothelial cell loss.

@entity1 @entity393 @entity1714 @entity2516
PURPOSE: To report long-term results of Artisan phakic intraocular lens (pIOL) to correct @entity1714 and to propose a model predicting endothelial cell loss after pIOL implantation. SETTING: Quinze-Vingts National Ophthalmology Hospital, Paris, France. DESIGN: Retrospective, interventional case series. METHODS: Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and central endothelial cell count (ECC) were determined before and at yearly intervals up to 5 years after pIOL implantation. Linear model analysis was performed to present a model that describes endothelial cell loss as a linear decrease and an additional decrease depending on postoperative loss. RESULTS: A total of 49 @entity1 (68 eyes) implanted with pIOLs from January 2000 to January 2009 were evaluated. The mean preoperative and final spherical equivalent (SE) were -13    4.10 and -0.75    0.74 diopters (D), respectively. The mean preoperative and final central ECC were 2629    366 and 2250    454 cells/mm(2), respectively. There were no intraoperative complications for any of the eyes. One eye required surgery for repositioning the pIOL, and 1 eye required pIOL exchange for postoperative @entity2516 . The model predicted that for @entity1 with preoperative ECC of 3000, 2500, and 2000 cells/mm(2), a critical ECC of 1500 cells/mm(2) will be reached at 39, 28, and 15 years after implantation, respectively. CONCLUSIONS: Implantation of the pIOL was an effective and stable procedure after 5 years of follow-up. The presented model predicted @entity393 after pIOL implantation, which can assist ophthalmologists in @entity1 selection and follow-up. FINANCIAL DISCLOSURE: The authors report no conflict of interest.
