Utilization of intravenously administered glycogen by young XXXX .

@entity1 @entity1707 @entity1735 @entity21840 @entity1718 @entity413
Previous studies evaluated solutions of small oligosaccharides as potential sources of @entity1735 -derived energy for @entity1 fed intravenously. Although results with these solutions were disappointing, the data suggested that very large oligosaccharides were potential sources of intravenous @entity1735 . To test this hypothesis, four young @entity1707 (3.6 +/- 0.2 kg; mean +/- SD) were infused with sterile solutions for a 6-d period. On days 1 and 6, a balanced isotonic electrolyte solution was infused. On days 2-5 a 9% solution of glycogen was infused at a rate providing 17.7 +/- 0.77 g/d. For each study day the remaining portion of the energy, protein, essential @entity1718 and micronutrients was supplied enterally. No adverse reactions were noted during glycogen infusion, and the animals continued to grow. Glycogen utilization was 66.4 +/- 4.3%. Of the total @entity1735 excreted, 85.4% was composed of oligosaccharides of maltotetraose size or larger. Free @entity413 accounted for 3.5% of the total excreted, while maltose plus @entity21840 accounted for 11.1%. Plasma concentrations of oligosaccharide-bound @entity413 increased during glycogen infusion, rising from a base-line value of 11.0 +/- 14 mg/dL to an overall mean value for the 4-d period of 100.3 +/- 31.6 mg/dL.
