Neutrophil chemiluminescence in burned XXXX .

@entity1 @entity697 @entity295 @entity894 @entity73 @entity69 @entity281 @entity4808
Phagocytic and bactericidal assays showed that a close correlation was present between bactericidal activity and neutrophil chemiluminescence (PMN-CL) (r = 0.81; p less than 0.01). This suggested that the microbicidal action of the neutrophil depends metabolically on the generation of oxygenating agents. PMN-CL and @entity894 ( @entity894 ) were measured in 36 burned @entity1 . The levels of serum @entity69 (Tf) were examined simultaneously by nephelometric method in order to determine the correlation between humoral-phagocyte axis of immune system and nutritional status. It was found that PMN-CL and @entity894 were generally lower in the greater than 35% TBSA burn group (PMN-CL, 1.85 +/- 0.21 cpm X 10(3), @entity894 , 0.69 +/- 0.06) compared with control subjects (PMN-CL, 3.55 +/- 0.15 cpm X 10(3), @entity894 , 1.05 +/- 0.04). It suggested that both neutrophil oxygenation activity and opsonic activity were @entity73 following severe @entity4808 . PMN-CL was higher in the smaller than 30% TBSA burn group during @entity281 phase as compared with control subjects (5.61 +/- 0.26 cpm X 10(3) vs. 3.55 +/- 01.5 cpm X 10(3); p less than 0.01). It remained high in @entity1 with persistent @entity281 , but fell to normal if appropriate therapy was instituted. This result indicated that the neutrophils of the majority of @entity1 with minor @entity4808 during @entity697 were in an activated state both metabolically and functionally. The occurrence of @entity295 was associated with a marked lowering of PMN-CL and @entity894 values, but no difference was noted before and after the development of @entity295 . The incidence of @entity295 was 85.7% when PMN-CL was lower than 2 cpm X 10(3).(ABSTRACT TRUNCATED AT 250 WORDS)
