Microscopic Nail Clipping Findings in XXXX With Psoriasis.

@entity1 @entity1569 @entity47540 @entity6313 @entity5441 @entity854 @entity7064
BACKGROUND: Nail clipping microscopy is a valuable diagnostic tool in @entity6313 but has not been explored for the diagnosis of @entity47540 caused by @entity1569 . The objective of this study was to try to establish criteria for the diagnosis of @entity1569 by this method. METHODS: Cross-sectional study of adult @entity1 with clear-cut @entity1569 is divided into 2 groups: (1) with @entity47540 and (2) with clinically normal nails. The @entity1 were evaluated regarding gender and age, among other clinical variables. The samples were coded to allow blinded microscopic interpretation for nail plate and subungual region thickness and for the presence or absence of corneocytes, neutrophils, serous lakes, blood, bacteria, onychokaryosis, @entity5441 nuclear shadows, and fungi. RESULTS: Ninety-six @entity1 with @entity1569 were enrolled in this study. There were 40 male and 56 female subjects; ages varied from 16 to 87 years (mean, 51 years). @entity47540 was detected in 51 @entity1 (53%). On average, nail plate thickness and subungual region thickness measured 0.44 and 0.19 mm in the @entity47540 group and 0.41 and 0.14 mm in the clinically normal group (P > 0.05). @entity7064 presented 4.5 layers of corneocytes, on average, in contrast to the average of 2.4 in the clinically normal-looking nails (P = 0.0004). Neutrophils (12%), serous lakes (46%), blood collections (11%), bacteria (74%), fungi (20%), onychokaryosis, and @entity5441 nuclear shadows were all more common in the @entity47540 group but not in a statistically significant standard when compared with the other group (P > 0.05). CONCLUSIONS: Nail clippings from @entity1 with @entity1569 present abnormally thickened subungual region with prominent hypercorneocytosis, serous lakes, bacteria, neutrophils, and blood collections. If fungi are present, usually there are spores. Clinically, normal-looking nails in @entity1 with @entity1569 can present @entity854 .
