[Cerebrovascular reactivity in XXXX (preliminary results)].

@entity1 @entity2175 @entity6 @entity3791 @entity413
AIMS: Previously numerous investigators reported about impairment of cerebrovascular reserve capacity in @entity6 . However, no similar data are available about @entity1 suffering from @entity2175 . The goal of the study was to assess cerebrovascular reserve in Type II @entity6 @entity1 . @entity1 AND METHODS: 14 @entity2175 @entity1 and 20 healthy controls were studied. Middle cerebral artery mean blood flow velocity was measured at rest and during 20 minutes after i.v. administration of 1 g. @entity3791 . Velocities measured after @entity3791 were compared to resting values and were expressed as the percent increase of the mean velocity. Data obtained in diabetics and healthy @entity1 were compared using Student's t-test. The correlation between age of the @entity1 , @entity6 duration, actual blood @entity413 -, insulin-, glycosylated hemoglobin-, urine microalbumin concentrations and resting blood flow velocity and cerebrovascular reserve capacity was assessed using linear regression analysis. RESULTS: Resting cerebral blood flow velocities, cerebrovascular reactivity and reserve capacity did not differ from that of healthy controls. No correlation has been found between obtained laboratory parameters and resting cerebral blood flow velocities and cerebrovascular reserve capacity. CONCLUSIONS: Vasodilatory ability of the cerebral arterioles in @entity2175 - @entity1 did not differ from that of healthy control @entity1 . Further studies are needed to find out an accurate screening method for detection of cerebral microangiopathic changes in @entity6 .
