The relationship between mediastinal lymph node attenuation with parenchymal lung parameters in XXXX .

@entity730 @entity82 @entity5636 @entity1600
OBJECTIVE: Attenuation changes on computed tomography (CT) in mediastinal @entity1600 ( @entity1600 ) may be related to lung alterations and functional impairment in @entity5636 . DESIGN: CT and clinical data of 41 (64.2 +/- 8.3 years) males with @entity5636 were retrieved. Attenuation type (calcified, hyperdense, normodense) and @entity730 pattern (central, eccentric, dense, eggshell, speckled) of mediastinal @entity1600 were evaluated; @entity1600 attenuation of uncalcified LNs quantified on CT in six @entity1600 stations. Nodular profusion (CT-NP) and progressive massive @entity82 (CT-PMF) were graded. Relationships between @entity1600 , CT, lung function and clinical parameters were determined. RESULTS: @entity1600 sites were paratracheal (n = 39), subcarinal (n = 39), tracheobronchial (n = 37), aortopulmonary (n = 37), hilar (n = 27), and peri-oesophageal (n = 21). LNs were calcified, hyperdense and normodense in 107, 85 and 54 @entity1600 stations, respectively. Uniformly calcified @entity1600 was most common, followed by speckled @entity730 . Central, eccentric and eggshell @entity730 was rare. CT-NP scores > or = 16 were associated with higher @entity1600 attenuation and number of calcified @entity1600 stations than CT-NP scores < 16. PMF had no influence over @entity1600 morphology or @entity730 pattern. @entity1600 attenuation correlated with CT-PMF (r = 0.36, P = 0.01), CT-NP (r = 0.54, P < 0.001) and DLCO/VA (r = -0.33, P = 0.02). CONCLUSION: Uniformly calcified and hyperdense LNs are common in @entity5636 , and eggshell @entity1600 @entity730 is rare. There are associations between @entity1600 attenuation and lung function impairment, and CT grades of nodular profusion and PMF.
