The role of @entity10221 in XXXX reproduction.

@entity1 @entity251 @entity43289 @entity9388 @entity3421 @entity1919 @entity10221 @entity15774 @entity12627
@entity10221 transcription factors are emerging as critical players in @entity1 reproductive development and function. @entity15774 contributes to fetal male gonadal development by regulating genes mediating M  llerian duct regression and the onset of @entity251 production. @entity12627 expression appears to be sexually dimorphic being transiently expressed in the germ cell lineage of the fetal ovary but not the fetal testis. In the reproductive system, @entity3421 is exclusively expressed in Sertoli cells at specific seminiferous tubule stages. In addition, @entity15774 and @entity43289 are localized primary to ovarian and testicular somatic cells. The majority of cell transfection studies demonstrate that @entity3421 and @entity15774 can stimulate inhibin subunit gene promoter constructs. Other studies provide strong evidence that @entity15774 and @entity43289 can activate genes mediating gonadal cell steroidogenesis. @entity12627 and @entity9388 are found in pituitary and placental cells and can regulate alpha-glycoprotein subunit gene expression. Gonadal expression and activation of GATAs appear to be regulated in part by gonadotropin signaling via the @entity1919 -protein kinase A pathway. This review will cover the current knowledge regarding @entity10221 expression and function at all levels of the reproductive axis.
