Microbiological characteristics of XXXX in @entity1 .

@entity1 @entity697 @entity5414 @entity4034 @entity794 @entity281 @entity582
UNASSIGNED: This study aimed to describe the microbiological characteristics of @entity5414 (SA) and @entity4034 ( @entity4034 ) in @entity1 . Cases of @entity1 (0-15 years) with SA/ @entity4034 were identified through a retrospective search of hospital discharge codes over a six-year period. In addition, a systematic literature search and meta-analysis of studies reporting culture results of @entity1 with SA/ @entity4034 was performed. In our retrospective chart review, we identified 68 cases of @entity4034 and 46 cases of SA. The most frequently cultured organisms in both conditions were Gram positive cocci, primarily @entity794 . On admission, most @entity1 had a normal WCC but elevated CRP and/or ESR. @entity582 was associated with a longer average length of hospitalisation for both @entity281 . Considering our results and the meta-analysis, we found low rates of culture-positivity in cases of clinically confirmed @entity281 . In SA, articular fluid was culture-positive in 42.49% (95% CI 28.39-57.23). In @entity4034 , intra-operative samples were culture-positive in 52.65% (95% CI 30.54-74.22,). @entity582 was detected in 23.91% (95% CI 8.40-44.24) of @entity1 with SA and 21.48% (95% CI 10.89-34.47) with @entity4034 . Despite appropriate sampling, a positive microbiological diagnosis is often lacking in paediatric @entity697 using standard culture-based methods. This highlights the need for validation and use of more sensitive diagnostic methods, such as PCR.
