Fetal limb soft tissue assessment for prediction of birth weight and umbilical cord blood analytes in gestational XXXX .

@entity1 @entity6 @entity442 @entity2690 @entity1307 @entity7396
OBJECTIVE: To evaluate the value of third trimester ultrasound (estimated fetal weight, cheek-to-cheek diameter, sectional Wharton's jelly area, sectional areas and fractional volumes in extremities) to predict birth weight and cord biochemical markers at birth (leptin, insulin, @entity2690 , @entity442 , @entity1307 and ferritin) in @entity6 . METHOD: Prospective study in 49 @entity1 with gestational @entity6 . An ultrasound was performed between 32 and 34   weeks. Clinical data were collected, and a blood sample was obtained from cord after birth. ROC curve models were evaluated for 75(th) and 90(th) birth weight percentile. Univariate and multivariate models were used to assess the association between ultrasound and neonatal outcomes. RESULTS: Sectional areas and fractional volumes showed significant differences and highest AUC values for predicting birth weight. A significant association was found for extremities measurements with total birth weight and its percentile. The only marker which showed a significant association to estimated fetal weight was @entity1307 . Sectional areas and fractional volumes related to cord leptin, @entity1307 , insulin and @entity2690 . CONCLUSION: Sectional areas and fractional volumes improve the predictive value of estimated fetal weight in @entity6 . They also show a predictive association to biochemical changes in cord (leptin, insulin and @entity1307 ) related to increased adiposity and risk of @entity7396 .    2015 John Wiley _ Sons, Ltd.
