Pars plana vitrectomy for XXXX . Internal limiting membrane delamination vs posterior hyaloid removal. A prospective randomized trial.

@entity1 @entity6 @entity1103 @entity941 @entity20699
BACKGROUND: @entity6 , as well as subsequent ocular complications such as @entity1103 ( @entity1103 ), are of fundametal socio-economic relevance. Therefore, we evaluated the influence of internal limiting membrane (ILM) removal on longterm morphological and functional outcome in @entity1 with @entity6 ( @entity6 ) type 2 and chronic @entity1103 without evident vitreomacular traction. METHOD: Forty eyes with attached posterior hyaloid were included in this prospective trial and randomized intraoperatively. Prior focal (n   =   31) or panretinal (n   =   25) laser coagulation was permitted. Group I (n   =   19 @entity1 ) underwent surgical induction of @entity20699 ( @entity20699 ), group II (n   =   20 @entity1 ) @entity20699 and removal of the ILM. Eleven @entity1 with detached posterior hyaloid (group III) were not randomized, and ILM removal was performed. One eye had to be excluded from further analysis. Examinations included ETDRS best-corrected visual acuity (BCVA), @entity941 angiography (FLA) and OCT at baseline, 3 and 6  months postoperatively. Main outcome measure was BCVA at 6  months, secondary was foveal thickness. RESULTS: Mean BCVA over 6  months remained unchanged in 85% of @entity1 of group II, and decreased in 53% of @entity1 of group I. Results were not statistically significant different [group I: mean decrease log MAR 95% CI (0.06; 0.32), group II: (-0.02; 0.11)]. OCT revealed a significantly greater reduction of foveal thickness following @entity20699 with ILM removal [group I: mean change: 95% CI (-208.95   m; -78.05   m), group II: (-80.90   m: +59.17   m)]. CONCLUSION: Vitrectomy, @entity20699 with or without ILM removal does not improve vision in @entity1 with @entity6 and cystoid @entity1103 without evident vitreoretinal traction. ILM delamination shows improved morphological results, and appears to be beneficial in eyes with preexisting @entity20699 .
