Rapid decrease in high density lipoprotein subfractions and postheparin plasma lipase activities after cessation of chronic XXXX intake.

@entity167 @entity5705 @entity9478 @entity412 @entity9477 @entity165
Regular intake of @entity167 is associated with elevated levels of high density lipoproteins (HDL). Opinions differ, however, on the HDL subfraction which is preferentially influenced by @entity167 . In the present study we measured the HDL subfraction lipid and protein concentrations and postheparin plasma lipase activities in chronic @entity167 users immediately after cessation of drinking and sequentially during one week of total abstention. The @entity9477 mass concentration decreased significantly already during two abstinent days the decline continuing until the 8th day. At this time the mean @entity9477 concentration had decreased by 38% from the initial value (P less than 0.05). The @entity9477 @entity165 , phospholipid and protein concentrations decreased in approximately similar proportions, whereas the @entity9477 @entity412 increased by 40%. The @entity9478 mass concentration decreased by 13% but this change was not significant. Also in @entity9478 the @entity165 , phospholipid and protein contents decreased to a similar extent but the @entity412 content rose. The postheparin plasma lipoprotein lipase activity decreased by 41% and the @entity5705 by 37% during the abstention. It is concluded that in chronic alcoholics @entity9477 accounts for the major part of the increase in HDL.
