Stage I noninvasive and minimally invasive XXXX : comprehensive @entity5 associated with improved survival.

@entity5 @entity1 @entity189 @entity1204
OBJECTIVE: The aim of this study was to determine if comprehensive surgical @entity5 is a better predictor of outcome than incomplete @entity5 for @entity1 with stage I noninvasive or minimally invasive ( <=3 mm) @entity189 ( @entity189 ). METHODS: Retrospective chart review was used to identify @entity1 undergoing hysterectomy at the Johns Hopkins Hospital from 1989 to 2010. Relevant clinical and pathologic data were extracted. @entity1 with noninvasive and minimally invasive ( <=3-mm myometrial invasion) @entity189 were identified. Stage was assigned based on the 2009 International Federation of Gynecology and Obstetrics @entity1204 criteria. Survival curves were generated using the Kaplan-Meier method. RESULTS: We identified 63 @entity1 with noninvasive or minimally invasive ( <=3 mm) @entity189 . Stages I, II, III, and IV disease were noted in 65% (41/63), 6% (4/63), 14% (9/63), and 14% (9/63) of the @entity1 , respectively. Lower stage was associated with a significantly improved disease-specific survival (P = 0.001). @entity5 , including total hysterectomy, bilateral salpingo-oophorectomy, pelvic and para-aortic lymphadenectomy, omentectomy, and peritoneal biopsies, was completed in 29% (12/41) of the @entity1 with stage I disease. There were no disease-specific deaths in the comprehensive @entity5 group. Compared with incomplete @entity5 , comprehensive @entity5 was associated with a significantly improved disease-specific survival (P = 0.039). CONCLUSIONS: @entity1 with stage I noninvasive and minimally invasive @entity189 on comprehensive @entity5 have an excellent prognosis. Adjuvant therapy may not benefit this @entity1 population.
