Lesion formation after pulmonary vein isolation using the advance cryoballoon and the standard cryoballoon: lessons learned from late XXXX enhancement magnetic resonance imaging.

@entity1 @entity47007 @entity75 @entity1347 @entity955 @entity2287
AIMS: To compare ablation lesion formation after pulmonary vein isolation (PVI) using the standard cryoballoon ( @entity47007 ) vs. the re-designed cryoballoon Arctic Front Advance (CB-A) using late @entity2287 enhancement magnetic resonance imaging (LGE-MRI) 3 months post-ablation. METHODS AND RESULTS: Thirty-six consecutive @entity1 with paroxysmal or short-lasting persistent @entity955 ( @entity955 ) were evaluated prospectively after PVI using the @entity47007 in the first 18 @entity1 and the CB-A in the subsequent 18 @entity1 . All @entity1 underwent LGE-MRI and a 7-day Holter electrocardiogram monitoring 3 months after ablation. Fifty-six per cent of the @entity1 were male (mean age 63.0    9.1 years). Fifty-six per cent in the first group and 89% in the second group were free of @entity955 recurrence 3 months after ablation (P = 0.025). Three months after ablation, LGE-MRI of the left atrium showed complete circular lesions in 35% of PVs in the first group and in 32% of PVs in the second group (n.s.). The left PVs showed a significantly higher proportion of @entity1347 compared with the right PVs (83 vs. 34%; P < 0.001). CONCLUSION: Cardiac MRI is able to visualize induced @entity75 after PVI and might be suitable to quantify ablation lesion amount. Ablation lesion formation did not differ significantly in @entity1 treated with the @entity47007 vs. the CB-A, despite a significantly lower rate of @entity955 recurrence after 3 months in the CB-A group. Left PVs showed a significantly higher amount of @entity75 compared with the right PVs. Larger and randomized studies are needed to understand the relationship between representable tissue lesions and success rates.
