Blastic natural killer-cell lymphoma of the skin associated with @entity2590 or XXXX : a coincidence or more?

@entity1 @entity10730 @entity27487 @entity404 @entity2940 @entity417 @entity2590 @entity1503 @entity1778 @entity1892 @entity272 @entity9713 @entity2981 @entity1141
We report three @entity1 with blastic natural killer (NK)-cell lymphoma of the skin associated with @entity2590 ( @entity2590 ) (two @entity1 ) or subacute @entity1778 (one @entity1 ). In two @entity1 @entity2590 was diagnosed before @entity272 ; the @entity1 with @entity1778 initially presented with @entity272 . Our @entity1 had several clinical features in common, namely multiple @entity272 with a @entity2981 -like appearance, involvement of the oral mucosa, and good general status at presentation but very rapid deterioration in the course of the disease. All @entity1 died of disease 4-14 months after the diagnosis. Histopathologically, there were cutaneous infiltrates of slightly pleomorphic medium-sized cells expressing @entity404 , @entity2940 , @entity10730 (focally) and being negative for surface CD3, cytotoxic molecules, B-cell-associated markers and myelomonocytic markers. Erythrocyte extravasation was seen in all @entity1 . T-cell receptor genes were in germline configuration. @entity2590 was classified as @entity1503 with @entity1141 and @entity27487 and @entity417 with transition to @entity417 . We reviewed similar cases reported in the literature showing coexistence of @entity1892 / @entity1778 and @entity2590 or @entity1778 . We conclude that given an overall limited number of reported cases of @entity1892 / @entity1778 , its association with various @entity9713 seen in a subset of @entity1 ( approximately 15-20%) is more than coincidental and may indicate their common origin.
