[A case of group B streptococcal occult XXXX ].

@entity1 @entity3524 @entity281 @entity1892 @entity2259
We reported an @entity1 with occult @entity2259 caused by @entity1892 ( @entity1892 ). An 8-week-old @entity1 , who was uneventfully born to an 18-year-old mother, was hospitalized because of a 4-hour history of fever. On admission, she appeared nontoxic, and the temperature was 39.0 degrees C, and the pulse and respiratory rates were 162/min and 42/min, respectively. Laboratory findings showed a total white blood count of 5,200/microliter with 44% neutrophils and C-reactive protein of 0.7 mg/dl. Cerebrospinal fluid and urine examinations did not disclosed any abnormalities. After a complete evaluation of sepsis including cultures from blood, cerebrospinal fluid, urine, stool, and throat swab, intravenous @entity3524 was administered at 100 mg/kg/day in three fractions. Nine hours after the start of the culture, @entity1892 was isolated from blood, and thereafter from the throat, but not from other culture sites obtained on admission. However, at that time she fed well and her temperature was subsiding. Forty-eight hours after admission, she became afebrile and @entity3524 administration was continued for 7 days. Based on the examinations of minimal inhibitory concentrations of various antibiotics, serotype analysis, and restriction-digestion patterns of genomic DNA, the 3 @entity1892 strains isolated from the @entity1 's blood and throat and the maternal anus were identical, suggesting that the @entity1 was infected by her mother. This is the first report in Japan describing the clinical course of @entity2259 . According to a case series published in the English literature and our case, there are few clinical and laboratory markers predictive for @entity2259 , but this condition may develop focal invasive @entity281 . A high index of suspicion is required for correct diagnosis. Further accumulation of such @entity1 is warranted to establish the appropriate treatment.
