Vascular distribution in ruptured XXXX cranial cruciate ligament.

@entity129 @entity11691 @entity235 @entity397 @entity528
OBJECTIVE: To (1) determine the microanatomic vascular distribution in ruptured @entity235 @entity129 ( @entity129 ) using specific vascular immunohistochemical techniques, and (2) compare vessel density between ruptured and intact @entity235 @entity129 and between different areas of interest in @entity397 using histomorphometric analysis. STUDY DESIGN: In vitro study. ANIMALS: @entity235 (n=41) admitted for surgical treatment of @entity397 and 19 @entity235 euthanatized for nonorthopedic conditions. METHODS: Diseased (variable @entity397 ) and intact (normal control) @entity129 were processed for immunohistochemical staining specific to vessels ( @entity11691 , laminin). Mean vascular density was assessed and compared in areas of interest (torn end versus remaining core regions of @entity129 , proximal femoral versus distal tibial core @entity129 regions). RESULTS: @entity397 was more vascular than intact @entity129 ; however there was no difference in vascular density between the torn end and the remaining core area of the @entity397 . @entity397 was vascularized to a greater degree at the proximal portion than the distal portion of the @entity129 . @entity397 CCLs had a higher vessel density than completely ruptured CCLs. CONCLUSIONS: Vascular density is increased in diseased @entity129 compared with intact @entity129 . It remains to be determined whether this finding is associated with the cause of @entity397 or is a result of @entity528 and @entity397 .
