@entity1313 imaging using a XXXX glioma model.

@entity3038 @entity1313 @entity235 @entity5 @entity7241 @entity10817 @entity2287
A @entity235 @entity3038 model was used to study the effectiveness of magnetic resonance imaging (MRI) with @entity2287 contrast enhancement in defining the histologic margins of @entity1313 . The effectiveness of this technique was compared to conventional computed tomography (CT) using iodinated contrast enhancement. Cultured @entity235 @entity3038 cells were injected into the left hemisphere of adult mongrel @entity235 . The @entity235 developed @entity1313 and progressive clinical signs. Serial MRI with and without @entity7241 was compared to serial CT with and without @entity10817 obtained on the same days. After the final scans, animals were sacrificed; the brains were removed and processed for routine histopathologic study. All @entity5 were visualized with contrast-enhanced MRI which proved most sensitive. @entity7241 caused bright enhancement of @entity5 in a distribution that consistently corresponded to areas of pathologically proved @entity5 infiltration. Gross and microscopic autopsy findings correlated better with MRI than with CT which tended to produce poorer resolution and underrepresent the size of viable @entity5 . @entity2287 -enhanced MRI is more accurate than unenhanced MRI, unenhanced CT, or enhanced CT in defining the histologic margins of @entity5 .
