Primary XXXX : case report with long-term clinical and MRI follow-up.

@entity1 @entity353 @entity5 @entity73 @entity294 @entity75 @entity344 @entity1595 @entity1599 @entity74 @entity490
UNASSIGNED: @entity1595 ( @entity1595 ) is a rare @entity74 caused by the bacteria @entity1599 . In its classic form, it manifests with @entity344 including @entity294 , @entity490 , and @entity353 . However, various other systems can be affected, including the central nervous system (CNS). Even more rarely, the CNS is primarily affected without @entity344 and with a negative small bowel biopsy. The incidence of primary CNS @entity1595 is unknown. We report the case of a young female with the primary CNS form of @entity1595 . In this report, we highlight the main clinical features and diagnostic procedures that lead to the diagnosis and comment on the treatment and clinical response. We stress the importance of neuroimaging and brain biopsy. A unique feature of this case is that the @entity1 has been followed up for 12 years. At the time of diagnosis, no neurological manifestations were detected, although @entity5 in the right temporal lobe and hypothalamic infiltration were present on magnetic resonance imaging (MRI). The first neurological manifestations developed 2 years later despite recommended antibiotic treatment, with @entity73 developing more than 10 years later. According to the MRI findings and clinical course, the disease was active for several years when @entity75 on MRI appeared despite antibiotic therapy. In the discussion, we compare the present case with similar cases previously reported and we elaborate on the similarities and discrepancies in clinical features, diagnostic procedures, results, and treatment options.
