Soy @entity6400 : no effects on bone mineral content and XXXX in healthy, menstruating young adult @entity1 after one year.

@entity1 @entity79 @entity6400 @entity3093
BACKGROUND: The effects of @entity3093 -enriched soy protein on @entity1 bone mineral content (mass) and density in healthy, menstruating young adult females have not been examined in a comparative prospective investigation. Peri- and post-menopausal @entity1 have been reported to show beneficial effects of @entity6400 on bone measurements. Therefore, young @entity1 may also be able to improve their accrual of peak bone mineral content (BMC) and @entity79 ( @entity79 ) during the early adult years of bone consolidation with an @entity3093 -enriched diet. OBJECTIVES: In this controlled, double-blind intervention, we tested the hypothesis that an @entity3093 -rich soy protein diet increases BMC and @entity79 in young adult females over a period of one year in comparison to a control group receiving soy protein that has @entity6400 removed. DESIGN: Young healthy @entity1 of any ethnic background, 21 to 25 years of age, were divided into two groups, placebo (n = 13) and supplement (n = 15). The soy protein supplement was enriched with @entity6400 ( approximately 90 mg of total @entity6400 /day), whereas the control protein diet was @entity3093 -deficient, even though it contained the same amount of soy protein and other ingredients as the @entity3093 -rich diet. Dual-energy x-ray absorptiometric (DXA) measurements of BMC and @entity79 were made at baseline and at 6 and 12 months. DXA estimates of body composition, including fat mass and lean body mass, were generated from whole-body BMC measurements. BMI was calculated as weight (kg) over height (m) squared. Physical activity was assessed, and three-day dietary records were taken at entry (baseline) and at 6 and 12 months. RESULTS: No changes in @entity79 after 12 months were found in either the @entity3093 -treated (treatment) group or the @entity3093 -deficient (control) group. Other variables also remained essentially constant over the 12-month period, including normal menstrual patterns in both the treatment and control groups. CONCLUSIONS: The @entity3093 -rich soy preparation had no effects on BMC and @entity79 over a 12-month period in young healthy adult females with normal menses. An @entity3093 -rich supplement appears to have little or no effect on bone in young adult @entity1 with normal ovarian function, at least over this 12-month study period.
