XXXX in Parma's adult general population: a focus on age of onset.

@entity2701 @entity10 @entity1605
UNASSIGNED: In the present paper, we focus on the age of onset for @entity2701 in a population-based sample in the Parma, distinguishing its different subtypes and considering definite and probable diagnoses. Age of @entity10 onset is a useful clinical feature for differential diagnosis between primary @entity10 and between primary and secondary @entity10 forms. A total of 904 subjects representative of the Parma's adult general population were interviewed face to face by a physician from the Parma @entity10 Centre, using a validated questionnaire specially designed for the diagnosis of primary @entity10 according to the @entity1605 . In the majority of subjects diagnosed with definite @entity2701 , age of onset was 39  years or less, while mean age of onset was 29.7  years (SD 16.3  years, range 5-79  years), the median being 25  years. Both infrequent and frequent episodic definite @entity2701 first occurred in the majority of cases in the second, third and fourth decades. Subjects with chronic definite @entity2701 reported a later onset in life (i.e. fourth, fifth and sixth decades). In our study, mean age of onset for probable @entity2701 was 23.7  years (SD 9.2  years, range 10-40  years) and the median was 22  years. In no case did we find significant gender differences. Our study results are similar to most of those reported in the literature. Further research needs to be done in the Italian epidemiological context, given the lack of literature reports on this topic.
