Psammomabody content and DNA-flow cytometric results as prognostic factors in advanced XXXX .

@entity43 @entity1 @entity189 @entity5
138 advanced @entity43 --all FIGO stages III/IV--were investigated by prognostic morphological @entity5 grading and rate of psammomabody content--subdivided in to @entity189 with a high, a moderate and a low rate of psammomabodies and a group of @entity189 without psammomabodies. Additionally 91 of these @entity5 were examined by DNA-flow-cytometry--respectively DNA-ploidy and s-phase-fraction. All prognostic factors were correlated to the overall survival time. The psammomabody content factor is only important if histologically a high or moderate rate of psammomabodies is found in the @entity5 tissue. Tumours with a low rate of psammomabodies do not differ from @entity5 without psammomabodies. DNA-flow-cytometry is a qualified method to demonstrate a slow @entity5 growth tendency. The majority of @entity189 with a high rate of psammomabodies is DNA-diploid and has a low -phase-fraction. The overall survival rate for these @entity5 is much better. @entity5 grading--a more subjective method--is also of high value, but there is a certain difficulty in reproducing the results in individual cases. By the combination of the two morphological methods--semiquantitative assessment of psammomabodies and DNA-flow-cytometry--we were able to discover a small group of @entity1 with advanced @entity43 who have a favourable prognosis.
