[ @entity5 with XXXX ].

@entity1 @entity6585 @entity5 @entity75 @entity2150 @entity205 @entity1893 @entity236
AIM: To detect and verify the existence of a specific form of T-cell @entity5 accompanied by @entity75 of bone marrow and @entity2150 . MATERIAL AND METHODS: Four @entity1 with @entity2150 were examined using clinical, histological, cytological, cytogenetic, and immunophenotypic methods. RESULTS: Four cases of @entity5 of bone marrow with clinical and morphological manifestations of @entity2150 and scanty proliferation activity in bone marrow alone were diagnosed. The proliferation activity in bone marrow was observed as formation of small clusters composed of small-size lymphoid cells with dense nucleus. Dynamic monitoring of two @entity1 revealed a trend toward an increase in the lymphoproliferation base against the remaining clinical picture of @entity2150 . The T-cell immunophenotype characterized by disappearance of some markers or decrease in their density, was observed only in some blood and bone marrow lymphocytes. The most significant changes of immunophenotype were observed in one of the @entity1 (CD2+CD3-CD4-CD5-CD7-CD8-CD16-CD56-CD45RO++). The same @entity1 had pronounced cytogenetic changes (47XY+Y[8], 47, XY, del(1)( @entity6585 ) [23], 46 XY [3]) and resistance to routine therapy, including @entity205 . In one @entity1 the process transformed into @entity1893 . CONCLUSION: The results obtained in four @entity1 allow their clinicomorphological characteristics to be regarded as particular forms of @entity5 accompanied by @entity236 and @entity2150 .
