Prevalence of bacterial pathogens in XXXX in a tertiary hospital, 1995-2001: any change in trend?

@entity1 @entity2782 @entity795 @entity130 @entity794 @entity2737 @entity4005 @entity526
BACKGROUND: Wound care is a very important aspect of surgical care. Knowledge of the epidemiology of bacterial pathogens associated with @entity2737 is critical in formulating policies on infection control. OBJECTIVE: To determine the prevalence of bacterial pathogens in wounds from various units of a Nigerian tertiary hospital orthopedics and traumatology department, as well as changes over time, if any, in the prevalence rates. METHODS: A retrospective study was conducted using laboratory records from 1995 to 2001. RESULTS: 670 bacterial isolates from 629 @entity1 were studied. The most common isolates were Pseudomonas spp.-29.9%, and @entity794 ( @entity794 )--27.5%. Others were @entity4005 spp.-18.5%, @entity795 spp.--15.1%, and @entity526 (E. coli)--7%. The least common were Streptococci--2%, and Enterococci--0.3%. Pseudomonas spp. accounted for 33% of isolates in the adult wards, while @entity794 was 21% and @entity526 8%. The pattem is similar in the pediatric ward (33.9%, 23.7%, and 8.5%, respectively) and Intensive Care Unit (ICU) (40%, 6.7%, and zero, respectively). @entity794 was the most common isolate from the orthopedic clinics (OPD) 40%, and the A_E (35%), followed by @entity2782 spp.-25.4% and 19%, respectively. The odds of a wound being infected with Gram-negative bacilli among inpatients compared with outpatients is 2.44 (95% CL = 1.72-3.47; P = 0.0000003) Between 1995 and 2001, the prevalence of Gram-positive bacteria decreased, while that of Gram-negative bacilli increased. The prevalence of Pseudomonas spp. and @entity794 also increased. CONCLUSION: Wounds from @entity1 in the orthopedics and @entity130 services are more frequently infected with Gram-negative bacilli than by Gram-positive bacteria. The prevalence of the former is higher in the ICU and least in the OPD. Pseudomonas spp. was the most common isolate. It was more common among inpatients, while @entity794 was more common among outpatients. The prevalence of Pseudomonas spp. in particular and Gram-negative bacilli in general is increasing.
