Yield of Repeat Endoscopy in XXXX with No @entity1141 and @entity258 : A Population-Based Study.

@entity1 @entity355 @entity5 @entity258 @entity420 @entity1141
BACKGROUND: The yield of early repeat endoscopy in @entity1 with @entity355 ( @entity355 ) is not well established. AIMS: To determine how often early repeat endoscopy detected missed @entity1141 or @entity420 ( @entity420 ) in a population-based cohort of @entity1 with @entity355 . Secondary aims were to identify risk factors for missed @entity1141 / @entity420 and compare detection of prevalent versus incident HGD/ @entity420 . METHODS: A population-based cohort of @entity355 subjects in Olmsted County, MN, was studied. @entity1 with @entity355 or @entity258 ( @entity258 ) who underwent repeat endoscopy within 24  months were included. Those with a worse histologic diagnosis on repeat endoscopy were considered to have missed @entity1141 / @entity420 . Baseline characteristics among @entity1 with and without missed @entity1141 / @entity420 were compared. The absolute numbers of asymptomatic prevalent or missed, and incident HGD/ @entity420 in the entire cohort were ascertained. RESULTS: Of 488 @entity355 cases, 210 were included for the primary aim of this study. Repeat endoscopy revealed four HGD/ @entity420 (1.9  %) and 16 @entity258 (8.8  %) for a combined miss rate of 9.5  %. Long-segment @entity355 (LSBE) and lack of PPI use were predictors of missed @entity1141 / @entity420 (P  =  0.008), but adherence to biopsy protocol was not. Increased prevalent HGD/ @entity420 (n  =  30) rather than incident HGD/ @entity420 (n  =  22) was identified during a median 4.8  years of follow-up in this cohort. CONCLUSIONS: @entity1141 / @entity420 is commonly missed at initial @entity355 diagnosis, particularly in @entity1 with LSBE and no PPI use. Efforts should be made to enhance the sensitivity of detecting @entity1141 / @entity5 around the time of initial @entity355 diagnosis.
