Percentiles for central blood pressure and pulse wave velocity in XXXX and adolescents recorded with an oscillometric device.

@entity1 @entity101 @entity1556 @entity65 @entity122
OBJECTIVE: In adults with arterial @entity101 , measuring arterial stiffness by pulse wave velocity ( @entity122 ) can determine the extent of cardiovascular subclinical organ damage. @entity122 has independent predictive value for cardiovascular events, but there are currently no recommendations for measuring @entity122 in @entity1 . In addition, central systolic blood pressure (cSBP) strongly reflects vascular changes. The aim of this study was to establish percentiles for cSBP and @entity122 in @entity1 and adolescents to evaluate and classify altered vascular function in youths. METHODS AND RESULTS: We measured @entity122 and cSBP with an oscillometric device with inbuilt ARCSolver-algorithm (estimated by using the brachial waveform) and calculated smoothed reference percentiles for 1445 @entity1 and young adults (49.5% female; 13.41      2.80 years, range 8-22 years; @entity122 4.67      0.34  m/s; cSBP 100.7      8.9  mmHg) using the LMS-method based on age and height. @entity122 and cSBP increased with age and height, but slightly differently for @entity1 and @entity1 , possibly reflecting different growth patterns. Between 8 and 21 years, @entity122 increased from 4.29      0.32 to 4.98      0.33  m/s in @entity1 and from 4.27      0.18 to 5.22      0.46  m/s in @entity1 . While @entity1 showed a minor increase in cSBP (91.2      7.5 to 109.1      8.6  mmHg), the cSBP in @entity1 ranged from 90.0      5.8 to 110.5      9.6  mmHg with a more pronounced increase between 14 and 17 years. CONCLUSION: These percentiles for @entity122 and cSBP can help define arterial stiffness in youths and contribute to risk stratification for @entity65 . For example, in @entity1 with @entity1556 or isolated systolic @entity101 , @entity122 and cSBP can provide additional information about the function of the vascular system, thereby strengthening intervention strategies.
