[Creation of a model for XXXX in @entity95 embryos].

@entity3570 @entity1 @entity1494 @entity1276 @entity853 @entity95 @entity9960 @entity451 @entity85 @entity1241 @entity250
@entity3570 causes @entity451 , @entity1241 , @entity1494 , @entity250 , @entity1276 and @entity853 in newborns. Its ethiology and pathogenesis are still not known, and probably multifactorial. AIM: To determine whether spinal cord exposition to the amniotic space causes a functional (impairment) and anatomic lesion similar to that of @entity1 @entity9960 . MATERIAL AND METHODS: Forty-eight fetal @entity95 underwent to create @entity3570 on the 23rd gestational day (term is 31 days). The procedure consisted of lumbosacral skin excision and posterior laminectomy. The fetuses are allowed to continue their gestation. On the 30th gestational by the operated fetuses were harvested, together with a group of nonoperated littermates for control. A clinical and neurologic evaluation was done, as well a study of somato-sensorial evoked potentials in the upper and lower limb and histologic study of the affected vertebral and cordial segment. RESULTS: The 26 surviving animals had @entity85 and lack of movement of the lower limbs. Evoked potentials showed absent response to stimuli in the lower limbs of animals with @entity3570 , whereas upper limbs and control animals did respond. Histologically the spinal cord of the operated @entity95 was uncovered and flattened. CONCLUSION: This model of @entity9960 in fetal @entity95 reproduces a variety of features similar to @entity1 @entity3570 , and hence can be used to study the pathophysiology of @entity3570 .
