Occupational asthma and XXXX in workers from a @entity71499 production line.

@entity1 @entity2490 @entity71499 @entity56 @entity1576 @entity9416 @entity7446
OBJECTIVES: A wide range of low-molecular-weight agents can cause @entity7446 . The chemical industry is an environment in which numerous hazardous substances are used. @entity71499 ( @entity71499 ) is one of them (along with its precursors). METHODS: Five @entity1 from a @entity71499 production line with suspected @entity7446 and @entity2490 were examined. During the first visit, skin prick tests, total @entity9416 ( @entity9416 ), a nonspecific bronchoprovocation test, and specific bronchoprovocation tests using occupational agents were performed to confirm the diagnosis of @entity56 . During the follow-up visit (1-3 years after removal from exposure), all of the tests (except the specific bronchoprovocation test) were performed again. RESULTS: At the first hospitalization, the total @entity9416 levels were increased in three @entity1 . In addition, skin prick tests and the nonspecific bronchoprovocation test were positive for three @entity1 . After the specific bronchoprovocation test, serious bronchoconstriction occurred in three @entity1 ; symptoms of @entity2490 were present in all five @entity1 . Several years after removal from exposure to the occupational agents, normalization (with respect to the parameters followed) was not yet complete for all of the @entity1 . CONCLUSIONS: The process of @entity71499 production seems to be hazardous and is likely to cause @entity1576 . The prognosis of @entity56 caused by these products is not very favorable. @entity56 (despite the removal from occupational allergen exposure) persisted even after several years.
