Involvement of oral tissues by XXXX : a literature review and report of eight new cases.

@entity1 @entity1582 @entity527 @entity2783
OBJECTIVE: @entity2783 is a term used to describe a group of diseases in which there is an extracellular deposition of amorphous fibrillar proteins known as amyloid. The aim of this study was to present clinicopathological data from eight oral @entity2783 @entity1 and a deep review of the literature about the disease. MATERIALS AND METHODS: A retrospective study was conducted based on the records of oral @entity2783 @entity1 diagnosed in our institution between 1978 and 2012. The clinicopathological features and immunohistochemical (IHC) staining with anti-kappa and anti-lambda light chain antibodies were carried out and analyzed. RESULTS: Eight @entity1 were diagnosed with the disease; the tongue and @entity1 in their sixth decade of life were mostly affected. All lesions demonstrated apple-green birefringence and immunoreactivity for kappa-light chain, and four cases also showed lambda positivity. According to our series, four cases were diagnosed with @entity2783 and four with @entity1582 . Prognosis for the systemic ones was gloomy, but good for the localized ones, which was characterized by a slow pattern of deposition without evolution to systemic involvement. CONCLUSIONS: This study reinforces our knowledge about predilections, outcomes, and the importance of making a correct and quick diagnosis of @entity2783 and shows the necessity of more studies detailing @entity2783 predilection on a global scale. The importance and utility of IHC in the typing of the biochemical nature of @entity527 are becoming increasingly necessary for proper management of the @entity1 . Correct classification of the type of amyloid is important for treatment consequences. CLINICAL RELEVANCE: This article highlights the clinicopathological data of @entity1 with @entity2783 affecting oral tissues and compare these new findings with other worldwide descriptions. Because of its rarity, such data are often unfamiliar to most clinicians and pathologists.
