Usefulness of programmed stimulation in predicting efficacy of @entity2779 in long-term antiarrhythmic therapy for paroxysmal XXXX .

@entity1 @entity2917 @entity591 @entity4710 @entity3153 @entity2779
The electrophysiologic effects of intravenous (i.v.) and oral @entity2779 were evaluated in 14 @entity1 with @entity3153 and in 10 @entity1 with @entity2917 reentrant @entity591 . The effective refractory periods of the right atrium and the AV node increased after both preparations. In @entity1 with @entity3153 , i.v. @entity2779 blocked anterograde accessory pathway conduction in 2 @entity1 and retrograde conduction in 1; during oral therapy, accessory pathway conduction block occurred in 2 additional @entity1 . The mean cycle length of the @entity4710 ( @entity4710 ) increased from 338 +/- 60 ms to 387 +/- 56 ms (p less than 0.05) after i.v. application, and from 336 +/- 65 ms to 367 +/- 65 ms (p less than 0.05) during oral @entity2779 . The shortest pacing interval maintaining a 1:1 AV conduction increased from 325 +/- 65 ms to 368 +/- 81 ms (p less than 0.05) after i.v. infusion, and from 333 +/- 57 ms to 369 +/- 75 ms (p less than 0.05) during oral therapy. There was no difference in the electrophysiologic effects between i.v. and oral @entity2779 . The induction of @entity4710 was prevented by i.v. @entity2779 in 10 of 20 @entity1 and in 4 additional @entity1 with oral @entity2779 . During follow-up, 6 of 7 @entity1 , whose @entity4710 could not be initiated by electrophysiologic drug testing, remained free from recurrences, whereas 5 of 7 @entity1 with inducible @entity591 had recurrences of @entity4710 . Thus, in @entity1 with @entity4710 , @entity2779 prolonged accessory pathway and AV nodal conduction and had a beneficial effect on circus @entity591 .(ABSTRACT TRUNCATED AT 250 WORDS)
