The adreno-sympathetic system, the genetic predisposition to XXXX , and stress.

@entity1 @entity1032 @entity101 @entity29597 @entity1425 @entity1882 @entity2922 @entity1063
The blood pressure, heart rate, and plasma @entity2922 (CA) response to standing and mental stresses were studied in 14 normotensive subjects with normotensive parents (PNT group), 14 normotensive subjects with @entity101 parent(s) ( @entity29597 group), and eight borderline @entity101 @entity1 (BHT group). Mean basal plasma @entity1063 (NE) concentration in BHT group (302 +/- 94 pg/ml) and PHT group (289 +/- 167 pg/ml) were significantly higher than in PNT group (205 +/- 76 pg/ml). Significant differences in the mean basal plasma @entity1425 (E) were found only between the PNT and BHT groups (22 +/- 12 vs 43 +/- 18 pg/ml, p less than 0.01). Both plasma NE and E increased significantly on standing in all groups. With @entity1032 , plasma E increased significantly, though plasma NE did not change significantly in all three groups. The mean changes in blood pressure, heart rate, and plasma CA in response to standing and mental stresses were not different in the three groups. However, a higher incidence (50%) of high blood pressure responders (greater than or equal to 20 mmHg in systolic blood pressure) to @entity1032 was found in the PHT group compared with PNT (14%) and @entity1882 (12%). The high responders in the PHT group had significantly higher mean plasma E concentrations throughout the experiment. Also, their increases in plasma NE and E in response to @entity1032 were higher than those of the low responders. The results indicate that genetic predisposition to @entity101 plays a significant role in determining plasma @entity2922 levels and the responsiveness to stress, especially to @entity1032 .
