Effects of dialysis solution on the cardiovascular function in peritoneal dialysis XXXX .

@entity1 @entity384 @entity2998 @entity65 @entity204 @entity298
Objective @entity298 ( @entity298 ) @entity1 have an increased cardiovascular burden. In this study, we aimed to compare certain @entity298 solutions (Physioneal(  ) and Dianeal(  )) in terms of the ambulatory blood pressure, echocardiographic parameters (ECHO), @entity2998 , endothelial function and serum asymmetric dimethylarginine (ADMA) level. Methods A total of 45 @entity298 @entity1 were enrolled in this prospective randomized controlled study: 23 @entity1 in the Dianeal(  ) group and 22 @entity1 in the Physioneal(  ) group. Ambulatory blood pressure measurements, echocardiography, carotid artery intima-media thickness measurements and @entity384 ( @entity384 ) and ADMA values were obtained at baseline and 12 months. Results The baseline parameters were similar between the groups with respect to the echocardiographic parameters, 24-hour ambulatory blood monitoring measurements and ADMA and @entity384 levels. All 24-hour blood pressure monitoring measurements, except for the average daytime systolic blood pressure, were significantly decreased in both groups at the first year. In the Physioneal(  ) group, a significant decrease was observed with regard to the ADMA levels. Considering the @entity384 values, significant augmentation was seen at the end of the first year in both groups. Improvements in the @entity384 measurements were prominent in the Physioneal(  ) group; however, this finding was not statistically significant. Conclusion The use of solutions with a neutral pH in @entity298 @entity1 results in decreased ADMA levels, which may be an important contributor to reductions in the incidence of @entity65 and @entity204 in this population.
