Leg XXXX as a long-term complication of @entity1150 .

@entity1 @entity174 @entity1066 @entity49 @entity1150 @entity1031 @entity6008
OBJECTIVE: To evaluate the role of @entity1150 as a cause of @entity6008 . @entity1 AND METHODS: A population-based, case-control study was conducted in Central and North Auckland, New Zealand. Cases comprised 241 @entity1 aged 40 to 99 years and on the electoral roll, with current @entity6008 (all types). Cases were identified by means of notification from health professionals and by self-referral. Controls were 224 @entity1 in the same age group, without @entity6008 , who were selected from the electoral roll by using a stratified random sampling process. MAIN OUTCOME MEASURES: The occurrence of leg @entity1066 as a consequence of exposure to @entity1150 or being at high risk of @entity1150 (that is, @entity1 with a family history of @entity1150 , and/or a history of @entity174 and/or hip, leg, or foot surgery). RESULTS: After adjustment for age, sex, and other potential confounding factors, @entity1 who had a diagnosed @entity1031 were at almost three times higher risk of having a leg @entity1066 (odds ratio, 2.92; 95% confidence interval (CI), 1.47 to 6.08). In addition, @entity1 who had been at high risk of a @entity49 but were not diagnosed with this condition (eg, @entity1 with a history of major leg surgery) were also at increased risk of @entity1066 (odds ratio, 2.25; 95% CI, 1.49-3.42). Overall, 56% (95% CI, 33% - 71%) of @entity6008 were attributed to being at high risk of @entity1150 . CONCLUSIONS: @entity1150 and factors that place @entity1 at high risk of @entity1150 are an important cause of @entity6008 in older @entity1 . This finding strengthens the rationale for the routine and long-term use of thromboprophylaxis, particularly in high-risk @entity1 .
