A comparison of @entity548 and transfusion in XXXX who undergo coronary artery bypass grafting via sternotomy with and without cardiopulmonary bypass.

@entity1 @entity453 @entity190 @entity548
OBJECTIVE: To determine whether there is a difference between on-pump cardiopulmonary bypass (CABG) and @entity453 ( @entity453 ) without heparin reversal with regard to @entity548 , transfusion requirements, and incidence of surgical re-exploration of the mediastinum. DESIGN: Retrospective chart review. SETTING: A large academic medical center. @entity1 : Two hundred adult @entity1 undergoing cardiac surgery. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: One hundred CABG @entity1 were compared with 100 @entity453 @entity1 . Statistical significance was measured with P values of <or=0.05. The heparin was not reversed in the @entity453 @entity1 . CABG @entity1 received more intraoperative allogeneic red blood cells (median 250 mL v 0 mL, p = 0.002), intraoperative autotransfusion (IAT) (550 mL v 425 mL, p = 0.001), platelets (9% v 1%, p = 0.009), and less albumin (0 mL v 250 mL, p = 0.001) than @entity453 @entity1 . Postoperatively, CABG @entity1 were more likely to receive fresh-frozen plasma (19% v 8%, p = 0.03) and less likely to receive IAT than the @entity453 group. During the initial 4-hour postoperative period, @entity453 @entity1 exhibited greater @entity190 via chest tube (290 mL v 385 mL, p = 0.003); however, at 12 hours and 24 hours postoperatively, there was no statistical difference in @entity190 between the 2 groups. There were no statistically significant differences in surgical re-exploration of the mediastinum between the CABG and @entity453 groups. CONCLUSION: Despite not reversing the heparin at the end of the @entity453 surgery, @entity453 surgery was associated with an overall reduction in allogeneic transfusion requirements.
