Quality of life and psychological well-being in Spanish long-term survivors of XXXX : results of a controlled pilot study.

@entity1 @entity308 @entity1353 @entity5 @entity148 @entity978
Nowadays, the chemoradiotherapeutic protocols for @entity978 ( @entity978 ) achieve high curability rates. Hemato-oncologists focus on both avoiding medical and psychological sequelae of the treatment and returning @entity1 to a normal life. The quality of life and psychological well-being of Spanish @entity1 who are long-term survivors of @entity978 were studied and compared to the results obtained from healthy controls. Questionnaires on quality of life [European Organization for Research and Treatment of @entity5 (EORTC) QLQ30] and psychological status [hospital @entity148 and @entity308 (HAD) scale] were mailed to @entity978 @entity1 without active disease and free of second @entity5 and were also given to healthy controls. Of 67 selected @entity1 (68.6%), 46 were included in this study. The median follow-up for these 46 @entity1 was of 7.6 years (0.8-22.1) after being diagnosed. Although there were no differences between @entity1 and controls with regard to their global state of health and quality of life (72.9+/-22.7 vs 79.3+/-18.7; p=0.22), @entity1 presented a lower physical function (88.2+/-18.1 vs 96.5+/-9.7; p=0.05) and a worse social operation scale (81.5+/-25.4 vs 96.3+/-13.1; p= 0.0015) together with higher symptoms of @entity1353 (8.6+/-14.7 vs 0+/-0; p=0.03) and higher economic difficulties (23.1+/-38.3 vs 0.7+/-4.9; p=0.017) when compared with healthy controls. However, we did not find differences in the scores and the proportion of cases of @entity148 and @entity308 between the two groups. The quality of life questionnaire disclosed differences between @entity1 and controls in some functional and symptomatic scales. These differences can be read as a consequence of either the disease itself or the treatment received. However, the results of this controlled pilot study should be confirmed in a larger series of Spanish @entity978 survivors. In the future, these results could be a reference when new therapeutic protocols are designed to reduce the impact on the quality of life of the @entity1 . Socioeconomic support to the @entity1 should also be provided in order to improve their medical care.
