Increased XXXX : a longitudinal study of their relationship in the community.

@entity1 @entity3556 @entity548 @entity458 @entity147 @entity1867 @entity3257
OBJECTIVE: To explore the temporal relationship between the development of self-reported symptoms of @entity3556 and the development of @entity458 among @entity1 in the community. DESIGN: Prospective cohort study using postal surveys at baseline and at 6 and 12 months. SETTING: An urban four-partner general practice with 10000 registered @entity1 . POPULATION: All @entity1 aged 18-54 years on the practice age-sex register. METHODS: Baseline postal questionnaire with follow up questionnaires sent at 6 and 12 months. MAIN OUTCOME MEASURES: The associations between the development of heavy periods and @entity458 . RESULTS: Two thousand and four hundred and thirty-five baseline questionnaires were sent out with an initial response rate of 76%. One thousand and five hundred and thirteen @entity1 (62%) responded to all three questionnaires. @entity1 with @entity458 at baseline were more likely to develop heavy periods 6 months later than @entity1 without @entity147 (adjusted odds ratio 1.87, 95% CI 1.15, 3.02). @entity1 with heavy periods at baseline were no more likely to develop @entity458 6 months later than @entity1 with @entity3257 (adjusted odds ratio 1.09, 95% CI 0.73, 1.63). Similar findings existed with respect to @entity1867 and @entity548 . Results of the 12-month analysis were similar. CONCLUSION: In the community, @entity458 appears to influence the future self-reporting of heavy periods and other symptoms of @entity3556 .
