Cytology for the detection of early recurrence of XXXX in the vaginal vault.

@entity1 @entity75 @entity5 @entity1204
OBJECTIVE: The real benefit of follow-up cervical cytology in @entity1 treated for gynecological @entity5 is unclear. This study was designed to assess the rate of success of cytological examinations in the detection of early vaginal recurrence of gynecological @entity5 in @entity1 found by other methods to have vaginal recurrence of cervical and @entity1204 . DATA SOURCES: Records of cytological examinations. STUDY SELECTION: Thirty-three @entity1 treated for early and invasive cervical and @entity1204 with recurrence in the vaginal vault were retrospectively analyzed. DATA EXTRACTION: Records from 1979 to 2010. DATA SYNTHESIS: Sixteen @entity1 (48.5%) had symptomatic vaginal recurrence associated with distant metastases, whereas 17 (51.5%) had vaginal recurrence only. Cytology was negative in 12 @entity1 (36.4%) with both symptomatic and asymptomatic recurrence and positive in the other 21 (63.6%). In 9 of these 21 @entity1 (42.9%), the disease was limited to the vaginal vault, whereas the remaining 12 (57.1%) presented with @entity75 associated with distant metastases. Cytology was positive in 9 of the 17 (52.9%) @entity1 whose recurrence was limited to the vaginal vault and negative in 8 (47.1%). CONCLUSION: Vaginal cytology yielded false-negative results in almost half of the @entity1 with vaginal recurrence of gynecological @entity5 . Patents of methods used for early diagnosis and detection of immortalization of cervical @entity5 are also reviewed in this article.
