[Cardiovascular autonomous dysfunction in diabetics: the influence of disease duration, glycoregulation degree and XXXX type].

@entity1 @entity6 @entity1723 @entity4148 @entity209 @entity551 @entity65
INTRODUCTION: @entity65 ( @entity65 ) in @entity6 has not been still defined clinically and aetiopathogenetically. OBJECTIVE: The aim of this study was to determine the influence of disease duration, glycoregulation degree and @entity65 in our group of @entity1 . METHOD: This study included diabetics, (100 @entity1 ) the same number of @entity1 with @entity1723 and II as well as 20 healthy individuals in the control group. Classic Ewing's cardiovascular tests were used for @entity65 diagnosis: (1) the cardiovascular response to Valsalva manoeuvre, (2) the cardiovascular response to deep breathing (the so-called E/I ratio), (3) the cardiovascular response to rising (the so-called 30/15 ratio), (4) the test of @entity551 and (5) the TA response to handgrip. It has been arbitrarily taken that @entity1 , whose score of "parasympathetic" tests (Valsalva manoeuvre, E/I ratio, 30/15) is equal or bigger than 1.5 (out of possible 3), have damage of the parasympathetic part of the @entity4148 while @entity1 , whose score of "sympathetic tests" (the test of @entity551 and TA response to hand-grip is equal or bigger than 1 (out of possible 2), have damage of the sympathetic part of the @entity4148 . The @entity1 whose total score is equal or bigger than 2 have @entity65 . The glycoregulation degree is determined by the level of HbA1c. RESULTS: There is a statistically significant, positive correlation between the values of the parasympathetic score and disease duration as well as between the total score, that is, @entity65 and disease duration. The connection between the sympathetic score, that is, damage of the sympathetic part of the @entity4148 and disease duration has not been observed. There is a positive correlation between the values of the parasympathetic score and HbA1c. The same pattern exists regarding the ratio of damage of the sympathetic part of the @entity4148 and the value of HbAlc, as well as the ratio of @entity65 , that is, the total score and HbA1c. Almost twofold, a bigger coefficient of correlation between the sympathetic score and HbA1c in relation to the coefficient of correlation of the parasympathetic score and HbA1c, points to bigger sensitivity of the sympathetic part of the @entity4148 to subacute deterioration of glycoregulation. The correlation between the values of autonomous scores and @entity6 type has not been noted. CONCLUSION: Our results show that besides disease duration, the subacute deterioration of glycoregulation also leads to the appearance of @entity65 in @entity6 . The sympathetic nervous tissue is functionally more sensitive than the parasympathetic one to @entity209 in @entity6 . The @entity65 will occur independently of the type of @entity6 .
