Macrophages and dendritic cells in the development of @entity99 leading to XXXX .

@entity1 @entity82 @entity1560 @entity8730 @entity469 @entity1578 @entity1575 @entity99
@entity1578 ( @entity1578 ) continues to be a serious problem due to different underlying disorders. Not only hepatocytes but Kupffer cells (KCs) and dendritic cells (DCs) are of importance in this instance. We wanted to investigate the possible role of KCs and liver DCs in the development of @entity99 in @entity1 with @entity1578 . Liver specimens from 23 @entity1 who died after @entity1578 were examined for the presence and distribution of @entity469 -positive KCs and @entity8730 -positive DCs by immunohistochemistry. The distribution of the @entity8730 -positive DC in the sinusoidal and the periportal spaces was not even. While 39.1% of @entity1 had a high sinusoidal density of @entity8730 -positive cells, 60.9% demonstrated a high density of @entity8730 -positive cells in the periportal tract. The number of @entity8730 -positive DCs in periportal tracts in @entity1 with advanced @entity1575 (n = 5) were high, while those with mild @entity1575 (n = 18) had low numbers of mature dendritic cells (  2=4.107; p=0.043). In addition, all @entity1 with intensive @entity82 had low counts of @entity469 -positive KC  s in portal tracts vs @entity1 with mild @entity82 of which 67% had high counts (  2=6.97; p=0.008). In seven of the @entity1 with moderate @entity1560 (87.5%) low numbers of @entity469 -positive KCs were found in sinusoids, in contrast to those with severe @entity1560 , where 12 @entity1 (80%) had high KC counts (  2=13.4; p less than 0.001). The distribution and number of @entity469 - positive KC and @entity8730 -positive DC reflect the progression of @entity1575 leading to @entity1578 .
