[Pathological study on the expression of cell adhesion molecules and @entity3 suppressor gene in XXXX and @entity1377 ].

@entity3557 @entity1377 @entity5962 @entity18962 @entity189 @entity1759 @entity6888 @entity3 @entity259
OBJECTIVE: To investigate the relationship between expression of cell adhesion molecular @entity1759 , @entity5962 ( @entity5962 ) and metastatic suppressor gene @entity18962 as well as the clinicopathologic features including cell differentiation, invasion and @entity3 of thyroid follicular-derived @entity189 . METHODS: Forty two (42) @entity259 ( @entity6888 ) and 54 @entity1377 ( @entity3557 ) were collected for studying the expression of @entity1759 , @entity5962 and @entity18962 using immunohistochemical staining. RESULTS: Neoplastic epithelium and infiltrating lymphocyte expressed @entity1759 in an intense plasma membrane pattern. @entity1759 expression rates in poorly differentiated @entity6888 (80%) and @entity3557 cases with @entity3 (78%) were significantly higher than those of well-differentiated @entity6888 cases (64%) and @entity3557 without @entity3 cases (59%) respectively. @entity259 tissue was positive for @entity5962 and @entity18962 in a cytoplasm pattern. Well-differentiated @entity6888 presented a higher @entity5962 and @entity18962 expression rate than poorly-differentiated @entity6888 , but both had a lower expression rate than that of @entity3557 (70% and 76%, P < 0.01). The expression rate and intensity of @entity5962 and @entity18962 were lower and less in metastatic @entity3557 than those in primary @entity3557 . Expression rate of @entity1759 (72%) in thyroid follicular-derived @entity189 was higher than those of @entity5962 (54%, P < 0.01) and @entity18962 (61%, P < 0.05). @entity5962 expression was adversely correlated with that of @entity18962 (chi(2) = 15.75, P < 0.011, r = 0.522 2). There was a reverse relationship between expression of @entity1759 and @entity5962 or nm23 (P > 0.05). CONCLUSIONS: Cell differentiation degree in @entity6888 and @entity3 in @entity3557 have positive correlation with the expression of @entity5962 and nm23, but have a reverse correlation with the expression of @entity1759 . There was a relationship between expression of @entity1759 , @entity5962 , nm23 and the characteristics of the degree of differentiation, metastatic potential and the prognosis of thyroid follicular-derived @entity189 .
