Association of gender to outcome after XXXX - a report from the International Cardiac Arrest Registry.

@entity1 @entity548 @entity55 @entity1272 @entity1167 @entity1371 @entity2332
INTRODUCTION: Previous studies have suggested an effect of gender on outcome after @entity1167 ( @entity1167 ), but the results are conflicting. We aimed to investigate the association of gender to outcome, coronary angiography (CAG) and adverse events in @entity1167 survivors treated with @entity2332 ( @entity2332 ). METHODS: We performed a retrospective analysis of prospectively collected data from the International Cardiac Arrest Registry. Adult @entity1 with a non-traumatic @entity1167 and treated with @entity2332 were included. Good neurological outcome was defined as a cerebral performance category (CPC) of 1 or 2. RESULTS: A total of 1667 @entity1 , 472 @entity1 (28%) and 1195 @entity1 (72%), met the inclusion criteria. @entity1 were more likely to receive bystander cardiopulmonary resuscitation, have an initial shockable rhythm and to have a presumed cardiac cause of arrest. At hospital discharge, @entity1 had a higher survival rate (52% vs. 38%, p   <   0.001) and more often a good neurological outcome (43% vs. 32%, p   <   0.001) in the univariate analysis. When adjusting for baseline characteristics, male gender was associated with improved survival (OR 1.34, 95% CI: 1.01-1.78) but no longer with neurological outcome (OR 1.24, 95% CI: 0.92-1.67). Adverse events were common; @entity1 more often had @entity1371 , @entity1272 and @entity548 requiring transfusion, while @entity1 had more @entity55 . In a subgroup analysis of @entity1 with a presumed cardiac cause of arrest (n   =   1361), @entity1 more often had CAG performed on admission (58% vs. 50%, p   =   0.02) but this discrepancy disappeared in an adjusted analysis. CONCLUSIONS: Gender differences exist regarding cause of arrest, adverse events and outcome. Male gender was independently associated with survival but not with neurological outcome.
