XXXX and @entity204 after coronary artery occlusion in the @entity35 . Continuous telemetric ECG monitoring in conscious, untethered @entity35 .

@entity1 @entity1165 @entity944 @entity235 @entity1188 @entity955 @entity1540 @entity35 @entity583 @entity943 @entity204
BACKGROUND: The onset of acute @entity583 ( @entity583 ) is accompanied by a rapid increase in electrical instability and often fatal @entity943 . The aim of this study was to assess the continuous @entity943 profile during the initial 48 hours after coronary artery ligation in the @entity35 in relation to time course, mortality, and @entity1188 size. METHODS AND RESULTS: Continuous ECG recording were obtained in 26 conscious, untethered @entity35 for 24 hours before and 48 hours after coronary ligation by use of an implantable telemetry system. All episodes of @entity1165 and @entity955 were counted and their durations summed. @entity1188 size was measured at 48 hours after @entity583 or after spontaneous @entity204 . After ligation, two distinctly active arrhythmogenic periods developed (A1, 0 to 0.5 hours; A2, 1.5 to 9 hours), each followed by a quiescent phase of low ectopy (Q1, 0.5 to 1.5 hours; Q2, 10 to 48 hours). The total mortality rate of 65% was found within the two active periods, with 13 of 15 @entity204 occurring in A2. @entity35 with larger @entity1188 (> or = 50%) and nonsurvivors tended to have increased @entity943 frequency and duration compared with both animals with smaller MIs (< 50%) and survivors. CONCLUSIONS: Two distinct arrhythmogenic periods occur in @entity35 with @entity583 that may be caused by different mechanisms and correspond to the bimodal @entity943 time course seen in @entity235 and @entity1 after @entity583 . Telemetric monitoring of the ECG in the conscious @entity35 after @entity1188 will be useful in assessment of the differential effects of therapeutic interventions on these two arrhythmogenic periods and in the study of potential mechanisms for the spontaneous resolution of @entity1540 and risk of @entity944 .
