Single centre experience of @entity15726 in postural XXXX .

@entity1 @entity1295 @entity1163 @entity591 @entity15726
AIMS: Postural @entity591 (POTS) is associated with @entity591 on orthostasis. @entity1 frequently report palpitations, @entity1163 , and @entity1295 . Conventional therapy is effective in less than 60%. Case reports suggest @entity15726 (a selective sinus node blocker, with no effect on blood pressure) may alleviate POTS-related symptoms. This is a retrospective case-series. METHODS AND RESULTS: Postural @entity591 @entity1 prescribed @entity15726 were identified from the pharmacy database. Case notes were reviewed and @entity1 completed a symptom assessment tool. Twenty-two @entity1 were identified. Data were available from 20. Eight @entity1 reported reduced @entity591 and @entity1295 and four reported only reduced @entity591 . The most common reason for discontinuing @entity15726 was lack of efficacy (n = 6). Five @entity1 reported side-effects resulting in two discontinuing treatment. CONCLUSION: This retrospective case series indicates that 60% of @entity1 treated with @entity15726 report a symptomatic improvement. A randomized controlled trial accessing the efficacy of @entity15726 in POTS is indicated, particularly in @entity1 resistant to, or intolerant of, conventional therapy.
