Gangliosides in various brain areas of three inbred strains of XXXX .

@entity19 @entity11688 @entity76 @entity4163 @entity7840
The @entity4163 patterns of @entity76 , cortex, pons-medulla, hypothalamus, hippocampus and caudate nucleus of three inbred strains of @entity19 (C57BL/6J, @entity7840 /2J and BALB/cJ) have been analysed. All brain areas contained both the simple and complex species of gangliosides. GD1a was the major @entity4163 in cortex, hippocampus and caudate nucleus whereas GT1b was the major species in @entity76 , hypothalamus and pons-medulla. In hippocampus, the percentages of GT1b and GD1a were quite similar. Pons and medulla exhibited the highest levels of @entity11688 (which approaches the value of GT1b) and the lowest values of GD1a. A @entity4163 , which was present in highest amounts in @entity76 disappeared after alkali treatment. Highly significant differences were observed in the amounts and patterns of gangliosides among brain areas of the three strains. Highly significant differences (p less than 0.001) were also found in the @entity4163 distribution of various brain areas among the strains, especially for tri- and tetrasialogangliosides between Balb and DBA. A significant difference of @entity11688 was observed in the @entity76 when comparing DBA with the two other strains. It is likely that the differences might be related to their relative abundances in certain cell types and for defining synaptic circuits in brain areas of some strains.
