@entity2100 and XXXX : two different forms of presentation of FSH-secreting @entity977 in adolescence.

@entity1 @entity4089 @entity9229 @entity28 @entity4611 @entity2100 @entity977 @entity1943 @entity7961
BACKGROUND: FSH-secreting @entity977 are extremely rare in @entity1 and are seldom associated with clinical manifestations of high serum gonadotrophin levels. Thus, most @entity1 have a late presentation, usually as macroadenomas. CASE REPORTS: Two different clinical forms of presentation of FSH-secreting @entity977 are reported: one in a 12-year-old @entity1 with @entity2100 due to a @entity4611 , probably FSH-secreting, and the other in a 15-year-old @entity1 with @entity7961 due to an FSH-producing macroadenoma. Both @entity1 presented slightly high or high FSH with low LH and high inhibin B levels. In the first case, the microadenoma was treated medically with @entity9229 , which failed to reduce FSH and inhibin B levels. No radiological progression has been observed despite increasing testicular volume. In the second case, surgery was performed on the macroadenoma, leading to a decrease in FSH and inhibin B levels. The @entity1 developed severe @entity28 and is currently under treatment with @entity1943 . CONCLUSIONS: FSH-secreting @entity977 have an extremely variable clinical expression. The discrepancy between normal or slightly increased FSH and low LH values, together with high inhibin B levels, strongly suggests FSH @entity4089 which should be studied.
