Long-Term Outcomes of Older Adults with and Without XXXX Immediately After Recovery from General Anesthesia for Surgery.

@entity933 @entity1 @entity260
OBJECTIVE: @entity260 , occurring days after surgery, is associated with both short- and long-term adverse events. Postanesthesia care unit (PACU) @entity933 , immediately after recovery from anesthesia, is associated with continued @entity933 in the succeeding days and adverse cognitive outcomes at discharge. Longer-term consequences are unclear. The objective was to evaluate 18-month outcomes of @entity1 with versus without @entity933 in the PACU after surgery with general anesthesia. METHODS: In a prospective, observational, cohort study, 91 consecutive English-speaking @entity1 , aged at least 70 years and capable of independently providing informed consent before surgery, were followed after admission for a surgical procedure in one teaching hospital. @entity1 completed cognitive testing before surgery. After recovery from general anesthesia, they were evaluated for a DSM-IV diagnosis of @entity933 . @entity1 or proxies were evaluated, at a median of 19 months after surgery (interquartile range: 18-20 months), for survival, cognitive and physical functioning, and healthcare utilization outcomes. RESULTS: All 91 @entity1 or proxies (41 with @entity933 [45%]) were contacted at follow-up, with 7 deaths (8%) and 3 declining further participation (3%); 81 (96% of survivors) completed follow-up evaluations, demonstrating no significant cognitive or functional decline from baseline, with 75% of the cohort living independently in the community, and no differences in any outcomes between @entity1 with versus without PACU @entity933 . CONCLUSION: In a small cohort of older @entity1 evaluated 18 months after surgery, we could not detect an association of @entity933 diagnosed in the PACU with @entity1 survival, cognitive/physical functioning, and healthcare utilization.
