[Detection, quantification and localization of XXXX : comparison of thallium single photon emission computer tomography with biplane angiography].

@entity1 @entity583 @entity1188
Thallium-201 single photon emission computed tomography (SPECT) is a new method for the scintigraphic visualization of the left ventricular myocardium. With SPECT a three-dimensional imaging by computerized slicing of the myocardium in various axes is possible. To investigate the capabilities of this new imaging technique, detection and quantification of remote transmural @entity1188 were compared with ventriculographic, coronarographic and electrocardiographic findings. 31 of 80 investigated @entity1 had had a prior @entity583 . The left ventricular myocardium was divided into 7 regions in the scintigraphic as well as in the angiographic studies. In a total of 560 segments the sensitivity of SPECT for @entity1188 detection was 87.5% with a specificity of 99.8%. @entity1188 which were not detected scintigraphically were relatively small (mean 13.5% of the circumference). To quantify the @entity1188 , the size of the defect was determined scintigraphically from a sagittal long axis and two short axes, and the images compared with angiographic @entity1188 sizes (% of the circumference) according to the method of Feild et al. A good correlation without overestimation of the size by one method (SPECT defect = 0.93 X ventriculographic defect - 1.2%; r = 0.7, p less than 0.001) was obtained. Also a good separation of the perfusion areas of the coronary arteries due to the three-dimensional imaging with SPECT was possible. Thus, by employing Thallium-201 SPECT of the left ventricular myocardium exact localization and quantification of transmural @entity583 with a positive predictive value of 98% can be achieved.
