The toxic effect of diquat on the XXXX lung after intratracheal administration.

@entity6453 @entity137 @entity8229 @entity358 @entity35
Diquat @entity137 to the lung was evaluated in @entity35 . Diquat was administered intratracheally (i.t.) and its toxic potential was compared with that of @entity6453 . Diquat showed toxic effects in the lung when administered i.t. In previous research, diquat administered by the intravenous (i.v.) or oral (p.o.) route had little effect on the lung. a sufficient dose of @entity8229 administered i.t. would be potentially toxic to the lung, but diquat is much less toxic to the lung than @entity6453 , which is actively taken up by lung tissue. This suggests that diquat is not actively taken up by lung tissue when administered i.t., but may be passively taken up by the lung tissue and induce @entity358 .
