Association of @entity1709 with XXXX and other @entity1374 and their relationship to the origin of the @entity1709 .

@entity1 @entity1375 @entity172 @entity1420 @entity1669 @entity1709 @entity5651 @entity4510 @entity195 @entity1374
@entity1709 is localized hyperpigmentation over the forehead, upper lips, cheeks, and chin. In this study, evidence suggesting an association between @entity1669 and @entity1709 and the relationship of @entity1374 to the origin of @entity1709 is presented. A total of 108 nonpregnant @entity1 , aged 20-56 yr, were divided into 2 groups for the purpose of this study: 1) @entity1709 , 84 @entity1 ; 2) control group, 24 @entity1 from the Dermatology Clinic matched for age and sex. @entity1374 ( @entity1374 ) were sought in all subjects. TRH-TSH tests were performed in @entity1 with @entity1709 and in those @entity1 with @entity5651 and/or positive @entity1374 tests from the control group. Studies were completed with serum T4, T3, and antithyroglobulin antibody (TGHA) measurements in all @entity1 with @entity1374 . In @entity1 with @entity1709 , the frequency of @entity1374 (58.3%) was 4 times greater than in the control group. The @entity1374 -negative @entity1 had 1) @entity4510 (13.1%), 2) @entity195 (2.4%), and 3) TSH hyperresponse to TRH in nongoitrous @entity1 (10.7%). @entity1 with positive @entity1374 tests (32.1%) were divided into 2 subgroups. One comprised those @entity1 with an apparently normal thyroid gland and thyroid function (n = 7), while the other included all @entity1 with @entity5651 and/or subclinical @entity1375 (n = 20). Regarding the origin of the @entity1709 , it was found that 70% of @entity1 who developed @entity1709 during pregnancy or while using oral contraceptives had @entity1374 compared to 39.4% of @entity1 with idiopathic @entity1709 . Subjects from the control group had a 12.5% incidence of @entity1374 , and only 8.3% had positive @entity1374 . @entity172 , @entity1420 , or both could be the triggering factor in the development of @entity1709 in @entity1 who have a particular predisposition toward both @entity1709 and @entity1669 . @entity1 with idiopathic @entity1709 had a lower frequency of @entity1374 , suggesting that there may be different genetic patterns linked to @entity1669 . We conclude that there is a true association between @entity1669 and @entity1709 , mostly in @entity1 whose @entity1709 develops during pregnancy or after ingestion of oral contraceptive drugs.
