Burden of Gastrointestinal and XXXX in Iran: Estimates Based on the Global Burden of Disease, Injuries, and Risk Factors Study, 2010.

@entity1 @entity1085 @entity82 @entity99 @entity10189 @entity698 @entity96 @entity5163 @entity294 @entity409 @entity1157 @entity344 @entity3851 @entity3621 @entity204 @entity166 @entity9317
BACKGROUND @entity409 ( @entity409 ) constitute a noteworthy portion of causes of @entity204 and disability in Iran. However, data on their prevalence and burden is sparse in Iran. The Global Burden of Disease (GBD) study in 2010 has provided invaluable comprehensive data on the burden of @entity409 in Iran. METHODS Estimations of @entity204 , years of life lost due to @entity204 (YLL), years of life lost due to disability (YLD), disability-adjusted life years (DALY), life expectancy, and healthy life expectancy have been reported for 291 diseases, 67 risk factors, 1160 sequelae, for both sexes and 19 age groups, form 1990 to 2010 for 187 countries. In the current paper, 5 major categories of @entity409 have been investigated as follows: GI @entity166 , @entity96 , @entity409 , @entity3851 , and other digestive diseases. RESULTS Among @entity1 , 7.6% of all @entity204 and 3.9% of all DALYs were due to digestive and @entity409 in 2010. The respective figures in @entity1 were 7.8% of @entity204 and 4.6% of DALYs. The most important cause of @entity204 among @entity1 under 5 is @entity294 . Among adults between 15 to 49 years old, the main causes of @entity204 are @entity96 and @entity82 , while @entity294 still remains a major cause of DALY. Among adults 50 years and above, @entity96 and @entity82 are the main causes of both @entity204 and DALYs. @entity3621 and @entity9317 , @entity5163 , @entity1085 and @entity1157 , @entity99 , @entity10189 , @entity698 , and @entity99 mainly cause disability rather than @entity204 . CONCLUSION GBD study provides invaluable source of data on burden of @entity409 in Iran. However, there exist limitations, namely overestimation of burden of @entity96 and underestimation of the burden of @entity344 that are usually diagnosed in outpatient settings. The collaboration of scientists across the world and specifically those from developing countries is necessary for improving the accuracy of future updates of GBD in these countries.
