[Clinical presentation and risk factors for surgery in XXXX ].

@entity1 @entity850 @entity30 @entity490
OBJECTIVE: To investigate the risk factors on initial surgery in @entity30 . METHODS: The clinical data of 173 @entity1 with @entity30 who were treated during 2010 and 2014 years in the Second Affiliated Hospital of Sun Yat-Sen University, were analyzed retrospectively. The @entity1 who had received intestinal resection or whose initial symptoms occurred at least 5 years at the end of the follow-up were recruited. Montreal classification was used to evaluate lesion location and disease behavior. The risk factors of the initial surgery were analyzed by using Logistic regression model. RESULTS: Eighty-five @entity1 (49.1%) received intestinal resection in 5 years after the onset of symptoms. The result of univariate analysis showed that the probability of surgical treatment is high in @entity1 who were male and those older than 40 years at diagnosis(P<0.05). Lesions involving upper digestive tract, @entity850 and penetrating lesions were also the risk factors on initial surgery in @entity30 (P<0.05). The result of multivariate analysis showed the relative risk of initial surgery was increased in male gender(OR=2.02, 95%CI:1.04-3.92) and in those who were older than 40 years at diagnosis(OR=2.34,95%CI:1.05-5.22). However, in @entity1 with @entity30 involving colon alone, the relative risk of initial surgery was decreased(OR=0.35, 95%CI:0.13-0.97). CONCLUSION: @entity490 is the most common clinical presentation in @entity30 . Disease behavior and operation is closely related. Older than 40 years at diagnosis and male gender is high risk factor for surgery while colonic lesion alone is protective factor.
