XXXX : Measuring intracranial volume change following fronto-orbital advancement using three-dimensional photogrammetry.

@entity1 @entity91
UNASSIGNED: There is still disagreement regarding the intracranial volumes of @entity1 with @entity91 compared with healthy @entity1 . This study aimed to compare the intracranial volume of @entity1 with @entity91 before and after surgery to an age- and sex-matched control cohort using three-dimensional (3D) photogrammetry. Eighteen @entity1 with @entity91 were operated on using standardized fronto-orbital advancement. Frontal, posterior and total intracranial volumes were measured exactly 1 day pre-operatively and 10 days post-operatively, using 3D photogrammetry. To establish an age- and sex-matched control group, the 3D photogrammetric data of 634 healthy @entity1 between the ages of 3 and 13 months were analyzed. Mean age at surgery was 9 months (SD 1.7). Prior to surgery, @entity1 with @entity91 showed significantly reduced frontal and total intracranial volumes compared with the reference group, but similar posterior volumes. After surgery, frontal and total intracranial volumes did not differ statistically from the control group. As @entity1 with @entity91 showed significantly smaller frontal and total intracranial volumes compared with an age- and sex-matched control group, corrective surgery should aim to achieve volume expansion. Furthermore, 3D photogrammetry provides a valuable alternative to CT scans in the measurement of intracranial volume in @entity1 with @entity91 , which significantly reduces the amount of radiation exposure to the growing brain.
