Interruption of Electrical Conductivity of XXXX Dental Implants Suggests a Path Towards Elimination Of Corrosion.

@entity1 @entity2133 @entity737 @entity79 @entity702
@entity737 is an inflammatory disease that results in the destruction of soft tissue and bone around the implant. @entity702 implant corrosion has been attributed to the implant failure and cytotoxic effects to the alveolar bone. We have documented the extent of @entity702 release into surrounding plaque in @entity1 with and without @entity737 . An in vitro model was designed to represent the actual environment of an implant in a @entity1 ' @entity2133 . The model uses actual oral microbiota from a volunteer, allows monitoring electrochemical processes generated by biofilms growing on implants and permits control of biocorrosion electrical current. As determined by next generation DNA sequencing, microbial compositions in experiments with the in vitro model were comparable with the compositions found in @entity1 with implants. It was determined that the electrical conductivity of @entity702 implants was the key factor responsible for the biocorrosion process. The interruption of the biocorrosion current resulted in a 4-5 fold reduction of corrosion. We propose a new design of dental implant that combines @entity702 in zero oxidation state for osseointegration and strength, interlaid with a nonconductive ceramic. In addition, we propose electrotherapy for manipulation of microbial biofilms and to induce @entity79 in @entity737 @entity1 .
