Neoadjuvant radiotherapy and reconstruction using autologous vein graft for the treatment of XXXX .

@entity1 @entity242 @entity5 @entity1822 @entity3 @entity6323
BACKGROUND AND OBJECTIVES: Inferior vena cava (IVC) @entity1822 are rare and are a relatively small subset of @entity242 . The current approach is resection and ligation or reconstruction of the IVC. This study was undertaken to analyze the outcomes associated with the use of neoadjuvant radiotherapy and IVC reconstruction in the treatment of @entity6323 . METHODS: A retrospective clinicopathological review of @entity1 treated during a 10-year period. RESULTS: Four @entity1 were treated with neoadjuvant radiotherapy, median 47.5   Gy, all underwent margin negative resection with 75% of the @entity5 being high grade and all @entity1 requiring resection of adjacent organs. Reconstruction of the IVC was performed with an autologous superficial femoral vein graft. There were no mortalities and the morbidity rate was 50%. At a median follow up of 37 months; two @entity1 had a patent IVC, no @entity1 had a local recurrence, and one @entity1 developed a distant @entity3 treated successfully with metastectomy. CONCLUSIONS: Neoadjuvant radiotherapy and resection of the @entity6323 resulted in 100% local control, and all @entity1 are alive at median follow up of 37 months. IVC reconstruction with the superficial femoral vein is safe and associated with acceptable short and long term morbidity.
