Bedside assessment of @entity121 muscle by ultrasound after admission for acute exacerbations of chronic XXXX .

@entity1 @entity1353 @entity26 @entity1576 @entity204 @entity121
RATIONALE: Hospitalization represents a major event for the @entity1 with chronic @entity1576 . There is a high risk of readmission, which over the longer term may be related more closely to the underlying condition of the @entity1 , such as skeletal @entity121 . OBJECTIVES: We assessed the risk of hospital readmission at 1 year, including measures of lower limb muscle as part of a larger clinical trial. METHODS: @entity1 hospitalized with an exacerbation of chronic @entity1576 underwent measures of muscle function including @entity121 ultrasound. Independent factors influencing time to hospital readmission or @entity204 were identified. @entity1 were classified into four quartiles based on @entity121 size and compared. MEASUREMENTS AND MAIN RESULTS: One hundred and ninety-one @entity1 (mean age, 71.6 [SD, 9.1] yr) were recruited. One hundred and thirty (68%) were either readmitted or died. Factors associated with readmission or @entity204 were age (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.08; P   =   0.015), Medical Research Council (MRC) @entity1353 grade (OR, 4.57; 95% CI, 2.62-7.95; P   <   0.001), home @entity26 use (OR, 12.4; 95% CI, 4.53-33.77; P   <   0.001), @entity121 (rectus femoris) cross-sectional area (Qcsa) (OR, 0.34; 95% CI, 0.17-0.65; P   =   0.001), and hospitalization in the previous year (OR, 4.82; 95% CI, 2.42-9.58; P   <   0.001). In the multivariate analyses, home @entity26 use (OR, 4.80; 95% CI, 1.68-13.69; P   =   0.003), MRC @entity1353 grade (OR, 2.57; 95% CI, 1.44-4.59; P   =   0.001), Qcsa (OR, 0.46; 95% CI, 0.22-0.95; P   =   0.035), and previous hospitalization (OR, 3.04; 95% CI, 1.47-6.29; P   =   0.003) were independently associated with readmission or @entity204 . @entity1 with the smallest muscle spent more days in hospital than those with largest muscle (28.1 [SD, 33.9] vs. 12.2 [SD, 23.5] d; P   =   0.007). CONCLUSIONS: Smaller @entity121 muscle size, as measured by ultrasound in the acute care setting, is an independent risk factor for unscheduled readmission or @entity204 , which may have value both in clinical practice and for risk stratification.
