Cryptococcal XXXX with multiple sites of involvement in the lower extremities.

@entity1 @entity2379 @entity39 @entity2380 @entity1327 @entity11937 @entity281 @entity364 @entity221 @entity2059
BACKGROUND: Cryptococcal @entity39 that is localized to the lower extremities is very rare. OBJECTIVE: We describe a case of a renal transplant recipient who presented with @entity39 caused by @entity11937 fungus that is rarely associated with this disease. METHODS: This is a case report with literature review. RESULTS: The @entity1 was hospitalized, and the site of infection was debrided to the level of the periosteum. Cultures and histopathologic examination of biopsy material revealed an invasive @entity281 with a fungal organism that was consistent with @entity1327 . After 21 days on parenteral @entity2379 (Ambisome; Er-Kim Pharmaceuticals) treatment, the @entity1 was switched to oral @entity2059 (Itraspor; Janssen-Cilag Pharmaceuticals) 200 mg/day. He was discharged after 30 days of hospitalization with his wounds completely healed. He continued on oral @entity2380 for a total course of 6 weeks. CONCLUSION: Systemic @entity364 continue to be an important cause of morbidity and mortality in transplant recipients. The insidious nature and atypical manifestations of these infections often delay diagnosis and therapy. In immunosuppressed @entity1 , persistent @entity221 that does not respond to antibacterial therapy should alert the physician to the possibility of @entity364 .
