Analysis of prognostic factors in @entity1 with XXXX treated with radiotherapy alone or in combination with systemic chemotherapy.

@entity1 @entity353 @entity5 @entity957 @entity189 @entity2802
OBJECTIVE: To assess the prognostic significance of several factors in @entity957 treated with radiotherapy alone or in combination with chemotherapy. DESIGN: Retrospective study. SETTING: Erasto Gaertner Hospital, Curitiba, Brazil, and A. C. Camargo Hospital, S  o Paulo, Brazil. @entity1 : A total of 361 @entity1 treated for @entity957 from January 1, 1990, to December 31, 2001. INTERVENTIONS: Radiotherapy alone or with chemotherapy. MAIN OUTCOME MEASURES: Disease-free survival, overall survival, and treatment response. RESULTS: Most @entity5 were located at the tonsil (46.8%) or base of the tongue (28.0%) and were at clinical stage III or IV (92.8%). Treatment response was associated with Zubrod scale score, @entity353 , number of comorbidities, symptom-severity and Piccirillo stages, hemoglobin level, @entity5 site, macroscopic appearance of the @entity5 , and clinical stage. The 5-year overall survival rate was 17.6% and disease-free survival rate was 16.2%. The significant prognostic variables were age; Zubrod scale score; @entity353 ; comorbidities; Berg, Piccirillo, and symptom-severity staging; involvement of adjacent soft-tissue areas and bone; lymph node mobility; clinical stage; and radiotherapy doses. The multivariate analysis showed Zubrod scale score, symptom-severity staging system, Berg staging system, comorbidities, and radiotherapy dose as independent prognostic factors. CONCLUSION: A combination of clinical factors, such as symptoms, @entity1 ' general status, @entity353 , and comorbidities, leads to a relevant stage of clinical severity that can be associated with the @entity2802 stage as predictors of survival in @entity189 .
