[Maintenance of the relation between the pulsed secretion of hormones and the internal sleep structure in @entity1 XXXX ].

@entity1 @entity1949 @entity4090 @entity701 @entity916 @entity7247 @entity25 @entity1319
In order to determine whether @entity25 would affect the hormonal patterns and the normal relationships between hormone pulses and sleep stages, the 24-hour profiles of @entity701 , @entity4090 and plasma @entity916 activity (PRA) were analysed in 6 @entity25 @entity1 studied at Brazzaville and in 5 healthy African controls studied in Abidjan. Polysomnographic recordings were done continuously and blood was taken every 10 minutes throughout the 24-hour period. Plasma was analyzed for @entity701 , @entity4090 and PRA. The circadian rhythm of @entity701 , considered as an example of an endogenous rhythm was attenuated in all the @entity1 but one, but as in normal subjects, @entity25 ( @entity25 ) remained associated with the declining phases of the secretory episodes. @entity4090 and PRA profiles, which are strongly influenced by the sleep-wake cycle did not show the increase normally associated with long sleep periods and reflected the spreading of sleep and wakefulness throughout the 24-hour period. However, @entity1319 ( @entity1319 ) sleep began in @entity25 @entity1 , as in normal subjects, during the descending phases of @entity4090 pulses. In both groups, PRA reflected the sleep stage distribution with non @entity1319 (NREM) sleep occurring during the ascending phases and @entity1319 sleep during the descending phases of the oscillations. However, in @entity25 @entity1 , the marked @entity1949 often did not allow sufficient time for PRA to increase significantly, as observed with regular NREM- @entity1319 sleep cycles. These results demonstrate that, together with the disruption of the sleep-wake cycle, there are profound differences in the temporal organization of the 24 hour hormone profiles in @entity1 @entity7247 .(ABSTRACT TRUNCATED AT 250 WORDS)
