In vivo comparison between XXXX and native @entity731 using near-infrared spectroscopy and intravascular ultrasound.

@entity1 @entity731 @entity460 @entity299
AIMS: The aim was to compare @entity299 to native @entity731 by near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS). METHODS AND RESULTS: Twenty-seven @entity731 (non-transplant) @entity1 and 28 heart transplant recipients undergoing routine surveillance coronary angiography underwent NIRS-IVUS imaging of the left anterior descending coronary artery. In each proximal, middle, and distal coronary artery segment, the maxLCBI4mm [4-mm long segment with maximum lipid core burden index (LCBI)] and corresponding IVUS parameters were compared. MaxLCBI4mm was significantly greater among @entity731 @entity1 than the transplant @entity1 in both proximal and middle coronary artery segments, but not in the distal segment. There was a positive linear correlation between maxLCBI4mm and maximum plaque burden in both groups, but @entity731 @entity1 demonstrated a smaller maxLCBI4mm than transplant recipients among segments with plaque burden <40%. Among segments with a maximum plaque burden >= 40%, native- @entity731 @entity1 had a greater maxLCBI4mm compared with transplant @entity1 (P = 0.015). Calcification was present in 72.9% of native @entity731 and 14.7% of transplant segments (P< 0.001). Among the 165 analysed segments, prevalence of lipid-rich plaque (LRP) with superficial attenuation (30.9 vs. 1.2%, P < 0.001) or calcified LRP (13.6 vs. 2.4%, P = 0.03) was significantly greater in native @entity731 compared with transplant @entity1 . Conversely, the proportion of segments with non-LRP (46.4 vs. 11.1%, P < 0.001) was higher in transplant @entity1 . CONCLUSION: NIRS-IVUS imaging demonstrated early and accelerated lipid accumulation with smaller plaque burden and less @entity460 in @entity1 after heart transplant when compared with @entity1 with native @entity731 .
