High-Resolution Vessel Wall Magnetic Resonance Imaging in Angiogram-Negative Non-Perimesencephalic XXXX .

@entity1 @entity548 @entity510 @entity439 @entity731 @entity2287
PURPOSE: Standard magnetic resonance imaging (MRI) rarely identifies the cause of @entity548 in @entity1 with an angiogram-negative, non-perimesencephalic @entity510 ( @entity510 ). Yet up to 10   % of these @entity1 have recurrent @entity548 . The aim of the study was to explore the potential role of high-resolution contrast-enhanced 3-Tesla vessel wall-MRI in @entity1 with angiogram-negative @entity510 . METHODS: We performed intracranial vessel wall-MRI of the circle of Willis using a 3-Tesla scanner in consecutive @entity1 presenting with a spontaneous, angiogram-negative, non-perimesencephalic @entity510 . Vessel wall-MRI included T1-, T2-, and @entity2287 -enhanced T1-weighted two-dimensional black-blood sequences in multiple planes (voxel size 0.4   *   0.4   *   2.0  mm). Two neuroradiologists independently scored abnormalities of the arterial wall. RESULTS: In all, 11 @entity1 (mean age 59 years) underwent vessel wall-MRI. A total of seven @entity1 had vessel wall abnormalities despite normal catheter angiography. Two @entity1 had focal abnormalities contiguous with the outer margin of the basilar artery wall for which we considered a differential of ruptured @entity439 , @entity439 , and loculated extramural blood from elsewhere. Two @entity1 had arterial wall enhancement involving multiple arteries, possibly secondary to @entity510 . Three @entity1 had arterial wall enhancement at sites of dural penetration, remote from the @entity510 , likely related to age and @entity731 risk factors. Vessel wall-MRI did not alter @entity1 management in this cohort. CONCLUSION: Vessel wall-MRI showed abnormalities in seven @entity1 with angiogram-negative @entity510 . These findings did not alter @entity1 management, but the findings may be useful for other physicians who choose to perform vessel wall-MRI in this @entity1 population.
