Radiofrequency ablation of XXXX : variability of lesion size using a single ablation device.

@entity1 @entity82 @entity99 @entity5
OBJECTIVE: In this study, we examined the variability of lesion sizes produced by a single radiofrequency ablation using the same device and algorithm in @entity1 with small malignant @entity99 . MATERIALS AND METHODS: A review of the clinical records of 208 @entity1 who underwent radiofrequency ablation of malignant @entity99 during a 6-year period revealed 31 @entity1 with small @entity5 that were treated with a single ablation. Clinical data were recorded using standardized work sheets. @entity5 and lesion sizes after ablation were measured from CT scans. The influences of @entity5 size, @entity5 type, presence or absence of @entity82 , and tissue temperature on the ablation size were analyzed. RESULTS: The size of @entity5 before treatment ranged from 0.8 to 4.0 cm (mean diameter [+/- SD] = 1.8 +/- 0.9 cm) with corresponding volumes of 0.27-30.24 mL (mean volume = 27.1 +/- 15.9 mL). The lesion sizes after ablation ranged from 1.7 to 5.3 cm (mean diameter = 3.6 +/- 0.7 cm) with corresponding volumes of 2.29-75.87 mL (mean volume = 4.9 +/- 7.1 mL). @entity5 type (p > 0.25), presence or absence of @entity82 (p > 0.45), and tissue temperature (p = 0.055) had no relationship to ablation size. @entity5 size had a statistically significant influence on ablation lesion size (p < 0.04). Ablation of small @entity5 (diameter < or = 2.25 cm, n = 32) produced random lesion sizes whereas ablation of large @entity5 (diameter > 2.25 cm, n = 11) produced larger lesions (mean diameter = 4.0 +/- 0.8 cm). CONCLUSION: Significant variation occurs in the lesion size produced using the same ablation device and algorithm. These findings must be considered when planning ablation strategies.
