Size and attenuation CT (SACT) of residual masses in XXXX with @entity1893 : more than a status quo?

@entity1 @entity536 @entity5 @entity1893
PURPOSE: To evaluate CT- @entity536 of residual masses in @entity1 with follicular @entity1893 (FL) at end-treatment compared to baseline mass density and determine its potential prognostic relevance. MATERIALS AND METHODS: 52 consecutive @entity1 with FL presenting with residual masses after chemotherapy receiving whole-body-CECT at baseline, end-treatment, and post-treatment were identified retrospectively by a search of our electronic medical record database from 2002 through 2010. An @entity536 ( @entity536 ), defined as the quotient of CT-attenuation [HU] between @entity5 and muscle was measured. Size was recorded as the product of long- and short-axis diameter of masses. In 38/52 @entity1 a follow-up period of >=  2 years was available to correlate results with relapse-free survival. RESULTS: @entity536 and @entity5 size of masses significantly decreased in responders when baseline was compared to end-treatment (n = 70; p < 0.05, respectively). An increase in both, @entity536 and size was recorded in case of relapse (n = 14; p < 0.05, respectively). 12/53 masses initially responded to therapy but relapsed within the consecutive 2-year period. The mean time to relapse was 13.5 months (range 5-24 months). @entity536 measured at the time of end-control was significantly lower in masses remaining stable for >=  2 years (n = 41) compared to masses with relapse during 2-year follow-up (n = 12; p < 0.05). At a threshold of an @entity536 >1 at end-control the specificity and sensitivity for relapsing disease within 2 years reached 83% and 75%, respectively. CONCLUSION: CT-attenuation measurements of residual masses in @entity1 with FL at end-control may aid in the risk stratification of early ( <= 2 years) relapsing disease.
