Bioassay of XXXX for possible carcinogenicity.

@entity35 @entity71048 @entity19 @entity5
A bioassay of @entity71048 for possible carcinogenicity was conducted by administering the test chemical in feed to F344 @entity35 and B6C3F1 @entity19 . Groups of 50 @entity35 of each sex and 50 @entity19 of each sex were administered @entity71048 at one of two doses, either 2,500 or 5,000 ppm, for 103 weeks, then observed for 2 additional weeks. Matched controls consisted of 50 untreated @entity35 of each sex and 50 untreated @entity19 of each sex. All surviving @entity35 were killed at 105 or 106 weeks and all surviving @entity19 at 104 or 105 weeks. Administration of @entity71048 had no appreciable effect on the mean body weights of the @entity35 and @entity19 of either sex. No clinical signs related to administration of the test chemical were noted in the @entity35 . Survivals of the @entity35 and @entity19 at the end of the bioassay were not affected by the test chemical. Both species may have been able to tolerate higher doses. In @entity35 and @entity19 of each sex, no @entity5 occurred at incidences that clearly were related to administration of the test chemical. Although it is recognized that both @entity35 and @entity19 may not have received a dose of the test chemical sufficiently high to provide maximum test sensitivity, it is concluded that under the conditions of this bioassay, @entity71048 was not carcinogenic for F344 @entity35 or B6C3F1 @entity19 .
