Emergency department CK-MB: a predictor of XXXX complications. National cooperative CK-MB project group.

@entity1 @entity662 @entity1455 @entity712 @entity943 @entity63 @entity341 @entity4207 @entity741 @entity8526 @entity583 @entity204
OBJECTIVE: To demonstrate that a positive CK-MB in the @entity341 ( @entity341 ) predicts an increased risk for complications of @entity741 in @entity1 admitted to the hospital for evaluation of @entity662 . METHODS: 53 @entity4207 and community hospital EDs participated in this prospective observational cohort analysis of 5,120 @entity1 with @entity662 without ST-segment elevation on the initial @entity341 12-lead electrocardiogram. All @entity1 were admitted for evaluation of @entity662 in one of the participating hospitals as part of the National Cooperative CK-MB Project. @entity1 were stratified by whether or not they had an elevated CK-MB level in the @entity341 . CK-MB measurements were made on @entity341 presentation and two hours later. @entity1 medical records were reviewed for inpatient @entity583 ( @entity583 ) or other diagnosis--and for @entity63 complication--cardiac-related @entity204 , recurrent or delayed in-hospital @entity583 , significant @entity943 , new @entity8526 , @entity712 , and @entity1455 . RESULTS: 369 (7.2%) of the 5,120 @entity1 had @entity583 . The proportion of @entity1 with any complication in the @entity583 group was 24%, while the complication rate in the non- @entity583 group was 0.4%. In all @entity1 , regardless of final diagnosis, the relative risk of any complication was 16.1 (95% CI 11.0-23.6) in those with a positive @entity341 CK-MB versus negative @entity341 CK-MB @entity1 . Similarly, the relative risk of @entity204 was 25.4 (95% CI 10.8-60.2) in positive @entity341 CK-MB versus negative @entity341 CK-MB @entity1 . CONCLUSIONS: Multicenter data support the hypothesis that CK-MB measurements can help risk-stratify @entity341 @entity662 @entity1 whose initial ECGs are without diagnostic ST-segment elevation.
