Exercise, education, manual-therapy and taping compared to education for XXXX : a blinded, randomised clinical trial.

@entity1 @entity571 @entity3331 @entity158 @entity4518
OBJECTIVE: @entity4518 ( @entity4518 ) contributes considerably to knee @entity571 symptoms. This study aimed to determine the efficacy of a PFJ-targeted exercise, education manual-therapy and taping program compared to @entity571 education alone, in @entity1 with @entity4518 . METHODS: A randomised, @entity1 -blinded and assessor-blinded clinical trial was conducted in primary-care physiotherapy. 92 @entity1 aged >= 40 years with symptomatic and radiographic @entity4518 participated. Physiotherapists delivered the PFJ-targeted exercise, education, manual-therapy and taping program, or the @entity571 (control condition) in eight sessions over 12 weeks. Primary outcomes at 3-month (primary) and 9-month follow-up: (1) @entity1 -perceived global rating of change (2) @entity158 visual analogue scale (VAS) (100  mm); and (3) activities of daily living (ADL) subscale of the @entity3331 and @entity571 Outcome Score (KOOS). RESULTS: 81 @entity1 (88%) completed the 3-month follow-up and data analysed on an intention-to-treat basis. Between-group baseline similarity for @entity1 characteristics was observed. The exercise, education, manual-therapy and taping program resulted in more @entity1 reporting much improvement (20/44) than the @entity571 group (5/48) (number needed to treat 3 (95% confidence interval (CI) 2 to 5)) and greater @entity158 reduction (mean difference:  -15.2  mm, 95% CI  -27.0 to  -3.4). No significant effects on ADL were observed (5.8; 95% CI  -0.6 to 12.1). At 9 months there were no significant effects for self-report of improvement, @entity158 (-10.5  mm, 95% CI  -22.7 to 1.8) or ADL (3.0, 95% CI  -3.7 to 9.7). CONCLUSION: Exercise, education, manual-therapy and taping can be recommended to improve short-term @entity1 rating of change and @entity158 severity. However over 9-months, both options were equivalent. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN12608000288325): https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=82878.
