Hippocampal cavities are not associated with cognitive impairment in XXXX .

@entity1 @entity10931
BACKGROUND: Hippocampal sulcal cavities (HSC) have been speculated to contribute to a higher vulnerability of memory pathways and might be a possible etiological factor in @entity10931 ( @entity10931 ). Therefore, we evaluated the influence of HSC on cognitive long-term outcome in @entity10931 - @entity1 . METHODS: Fourteen otherwise healthy @entity1 with the clinical syndrome of @entity10931 in their history underwent a high-resolution magnetic resolution imaging and a comprehensive neuropsychological test battery. The neuropsychological control group consisted of 15 healthy subjects and was balanced for age, sex and other risk factors as well as intellectual and social status. RESULTS: Magnetic resolution imaging and neuropsychological testing have been performed 1128 days (median) after the @entity10931 . HSC have been detected in nine of the 14 @entity1 and have been bilateral in eight of them. There were no differences in cognitive performance in @entity1 with and without HSC as well as compared to healthy subjects. Even in @entity1 with greater lesion load, only a slight visuospatial deficit was found. CONCLUSIONS: Although an increased incidence of HSCs is detected in @entity10931 @entity1 , cavities are not obligatorily in @entity10931 . Moreover, even @entity1 with hippocampal cavities achieve a full neuropsychological recovery independent of the frequency and size of the hippocampal lesions.
