Intraocular pressure changes associated with tracheal extubation: Comparison of XXXX with conventional reversal of @entity4094 .

@entity1 @entity4094 @entity726 @entity4858 @entity3897 @entity1339 @entity19271
OBJECTIVE: To compare the effects of @entity1339 / @entity3897 combination and @entity19271 on intraocular pressure during tracheal extubation period. METHODS: The single-blind prospective randomised controlled study was conducted at Ordu University Research and Training Hospital from August to October 2014, and comprised @entity1 who were randomly assigned to 2 groups according to the agent used for reversal of @entity4094 . Group N received 0.05mgkg-1 @entity1339 and 0.02 mgkg-1 @entity3897 and the @entity1 in Group S received 2mgkg-1 @entity19271 intravenously. Heart rate, mean arterial pressure and intraocular pressure were measured at baseline, before the induction (T1), after the application of reversal agent (T2), and 1 (T3), 3 (T4), 5 (T5) and 10 (T6) minutes after the extubation. SPSS 16 was used for statistical analysis. RESULTS: There were 36 @entity1 in the study; 18(50%) in each group. There was no significant difference between the groups in terms of age, gender and body mass index (p>0.05 each). Intraocular pressure was significantly higher when the baseline level was compared with all measurement intervals in Group N (p<0.05 each). In Group S, it showed no significant difference at T2 (p>0.05) whereas it was significantly higher at all other measurement intervals (p<0.05 each). Intergroup comparisons showed statistically significant difference in heart rate and mean arterial pressure levels at T2 interval which were higher in Group N (p<0.01). Intraocular pressure levels at T2 and T3 intervals were significantly higher in Group N (p<0.01). CONCLUSIONS: Lower end-extubation intraocular pressure levels were obtained when @entity19271 was used as a @entity4094 reversal agent in comparison with @entity1339 - @entity3897 combination. @entity19271 may be a better option for the reversal of @entity4094 and intraocular pressure increase should be avoided in @entity1 with @entity726 or penetrating @entity4858 .
