Evaluation of fine-needle aspiration biopsy under direct vision gastrofiberscopy in diagnosis of diffusely infiltrative XXXX .

@entity1 @entity5 @entity2681 @entity1066 @entity189 @entity1003
The accuracy of diagnosis of diffusely infiltrative @entity189 by direct endoscopic biopsy and cytologic examination were examined. A histologic diagnosis was made in 54 (83.1%) and a cytologic diagnosis in 49 (75.4%) of 65 @entity1 . By combined histologic and cytologic examinations, the overall diagnostic rate was raised to 87.7%. False-negative results were most frequent for @entity5 without @entity2681 or shallow @entity1066 . Positive diagnoses from histologic examination were usually obtained from @entity2681 or @entity1066 rather than from normal-appearing mucosa. These findings indicate that endoscopic detection of erosion or @entity1066 and subsequent biopsy are important for the diagnosis of diffusely infiltrative @entity189 . The authors developed a procedure for heparinized fine-needle aspiration biopsy under direct vision with a gastrofiberscope. In this procedure, heparinization of the needle and injector prevented @entity1003 . This made it possible to obtain good smears containing less degenerated @entity5 cells, and to obtain histologic materials. By this method, a correct cytologic diagnosis was made in all 11 @entity1 examined. Histologic material was obtained from four @entity1 in whom histologic and cytologic information on @entity5 could not be obtained by routine endoscopic examination.
