XXXX in the first 3 years of life: an electroclinical study of 46 cases.

@entity1 @entity410 @entity1032 @entity302 @entity2048 @entity3148 @entity950
PURPOSE: Early onset @entity2048 have been considered a rare heterogeneous group with a poor prognosis. Only few @entity1 may be categorized into well-known syndromes. We have evaluated electroclinical features, evolution, and the nosologic boundaries of early onset @entity2048 . METHODS: Forty-six neurologically normal @entity1 with @entity2048 associated with bilateral, synchronic, or asynchronic, and symmetric or asymmetric spike-and-wave paroxysms with onset in the first 3 years of life were included. @entity1 with abnormal neurologic examination and brain imaging were excluded from the study. KEY FINDINGS: In our study, 39 @entity1 met the clinical and electroencephalography (EEG) criteria of well-defined @entity302 . @entity2048 was found in 11 @entity1 , @entity3148 in @entity950 in 18 @entity1 , eyelid @entity3148 in 4, and @entity302 with @entity3148 in 6. We did not find clinical and EEG criteria of well-recognized @entity302 in seven @entity1 . Nine of 11 @entity1 with simple @entity2048 became @entity410 free. All these @entity1 had normal neurologic and neuropsychological evaluations. Of the 35 @entity1 who had @entity2048 associated with @entity410 , 20 became @entity410 free. Fifteen of 35 @entity1 continue having @entity410 . At the last visit, 20 of these 35 @entity1 had normal neurologic and neuropsychological evaluations, 11 presented with mild @entity1032 , and 4 with severe @entity1032 . SIGNIFICANCE: @entity302 with @entity2048 of early onset are relatively uncommon. Most of the @entity1 had well-defined @entity302 with a variable evolution. The evolution depended on the @entity302 .
