Castration attenuates prolactin response but potentiates ACTH response to conditioned stress in the XXXX .

@entity586 @entity3449 @entity2819 @entity35 @entity587 @entity3800
The purpose of this study was to examine the effect of circulating @entity3800 on neuroendocrine, autonomic, and behavioral responses to stress. The effects of conditioned stress were studied in male @entity35 that were intact, gonadectomized, or gonadectomized and treated with @entity586 ( @entity587 ). Intact animals received sham surgeries. Animals were stressed 3 wk after surgery. The adrenocorticotropic hormone (ACTH) response to conditioned stress was significantly potentiated (P < 0.01) in gonadectomized males compared with sham-operated and gonadectomized @entity587 -treated animals. In stressed @entity35 , plasma @entity2819 levels were significantly higher (P < 0.05) in gonadectomized animals compared with @entity587 -treated castrates. The prolactin response to stress was decreased (P < 0.01) in gonadectomized males compared with sham-operated and gonadectomized @entity587 -treated @entity35 . The stress-induced increases in plasma @entity3449 activity and concentration were not altered in gonadectomized or in gonadectomized @entity587 -treated animals. Nonstressed @entity587 -treated castrates exhibited more "fearlike" behavior compared with nonstressed sham-operated and gonadectomized animals. However, conditioned stress produced the same behavioral effects in all treatment groups. The results demonstrate that the ACTH/ @entity2819 , prolactin, and behavioral responses to a psychological stressor are differentially regulated by circulating @entity3800 .
