United airways again: high prevalence of rhinosinusitis and XXXX in @entity4595 .

@entity1 @entity5254 @entity4595 @entity1412 @entity480
BACKGROUND: Although various relationships between the lower and upper airways have been found, the association of @entity4595 with chronic rhinosinusitis and @entity480 has not been thoroughly evaluated. This study was undertaken to examine the association of @entity4595 with chronic rhinosinusitis and @entity1412 . METHODS: In a prospective study, 56 @entity1 with idiopathic and 32 with postinfective @entity4595 were evaluated for chronic rhinosinusitis and @entity1412 by using EP(3)OS criteria and assessing: symptoms score, nasal endoscopy, sinonasal and chest CT scan, nasal and lung function and nasal and exhaled NO. RESULTS: Most @entity4595 @entity1 (77%) satisfied the EP(3)OS criteria for chronic rhinosinusitis, with anterior (98.5%) and posterior (91%) @entity5254 and nasal congestion (90%) being the major symptoms. @entity1 presented maxillary, ethmoidal and ostiomeatal complex occupancy with a total CT score of 8.4 +/- 0.4 (0-24). Using endoscopy, @entity480 with a moderate score of 1.6 +/- 0.1 (0-3) were found in 25% of @entity1 . Nasal NO was significantly lower in @entity1 with @entity1412 (347 +/- 62 ppb) than in those without them (683 +/- 76 ppb; P < 0.001), and inversely correlated (R = -0.36; P < 0.01) with the ostiomeatal complex occupancy. In the chest CT scan, @entity1 with chronic rhinosinusitis showed a higher @entity4595 severity score (7.2 +/- 0.5; P < 0.001) than @entity1 without (3.7 +/- 0.7). The prevalence of chronic rhinosinusitis, @entity480 and other outcomes were similar in @entity4595 . CONCLUSIONS: The frequent association of chronic rhinosinusitis and @entity1412 with idiopathic and postinfective BQ supports the united airways concept, and it suggests that the two type of @entity4595 share common etiopathogenic mechanisms.
