Comparison of early outcomes and quality of life after laparoscopic Heller's cardiomyotomy to peroral endoscopic myotomy for treatment of XXXX .

@entity1318 @entity1 @entity190 @entity354 @entity1282 @entity158
BACKGROUND AND AIM: This retrospective cohort study compared clinical outcomes and quality of life after peroral endoscopic myotomy (POEM) against laparoscopic Heller myotomy (LHM) for treatment of @entity1318 . METHODS: @entity1 demographics, operation time, intraoperative @entity190 , hospital stay, time to resume diet and analgesic requirement were recorded. Clinical outcomes including recurrence of @entity1282 , need for reintervention, and occurrence of @entity354 ( @entity354 ) were recorded. RESULTS: From 2001 to 2014, 33 @entity1 underwent POEM whereas 23 @entity1 received LHM. @entity1 LHM had with longer mean operative time (P   =   0.02), more @entity190 (P   =   0.001) and higher requirement for analgesics (P   =   0.009) than those treated by POEM. Hospital stay and time to resume diet were similar. Both POEM and LHM achieved similar @entity1282 scores at postoperative 4 weeks, 3 months and 6 months. Twenty-six percent of LHM @entity1 and 15.2% of POEM @entity1 sustained @entity354 ( @entity354 ) after treatment (P   =   0.311). Six @entity1 required regular proton pump inhibitor three after POEM and three after LHM (P   =   0.639). Thirteen percent of LHM @entity1 sustained recurrent @entity1282 and one required reintervention. There was no recurrence in the POEM group. Follow-up duration (mean [SD]) for the LHM group was significantly longer (60 [42] months vs 6 [4] months; P   =   0.001). There was also no difference in all four aspects of @entity354 -related quality of life outcomes. CONCLUSION: Compared to LHM, POEM achieved shorter operative time, less @entity190 and @entity158 . POEM is comparable to LHM for treatment of @entity1318 with similar incidence of @entity354 after the procedure.
