Combination of XXXX and @entity3303 for @entity158 Control During Transrectal Ultrasound-guided Prostate Biopsy: A Randomized Double-blinded Study.

@entity1 @entity227 @entity1340 @entity3303 @entity158
OBJECTIVE: To evaluate the efficacy of @entity1340 , @entity3303 , and a combination of @entity1340 with @entity3303 in @entity158 relief using periprostatic nerve block technique by guidance of transrectal ultrasound (TRUS) before the prostate biopsy (PBx). MATERIALS AND METHODS: For the indication of TRUS-PBx, the @entity1 with a prostate-specific antigen (PSA) level >4.0  ng/mL or abnormal digital examination findings were selected. The @entity1 were randomized through random method. Group 1: @entity1 were administered 5  mL of 2% @entity3303 ; group 2: @entity1 were administered 5  mL of 25-mg @entity1340 ; and group 3: @entity1 were administered 5  mL of 2% @entity3303  + 25-mg @entity1340 . The procedures were completed in 10  minutes, and a @entity227 scale was administered to the @entity1 to question the @entity158 severity. RESULTS: TRUS-guided PBx was performed in 60 @entity1 with an age range of 57-77  years (mean age, 66.2     7.49  years) and a PSA range of 1-1000  ng/mL. The mean PSA level of the groups was 28.5  (  7.5), 16.1 (  5.0), and 14.9 (  2.9) ng/mL, respectively. The postprocedural @entity158 scores by @entity227 scale were 4.6    1.2, 5.4    1.2, and 3.6    0.9 in @entity3303 , @entity1340 , and @entity3303  + @entity1340 groups, respectively. CONCLUSION: Periprostatic nerve block is the current golden standard method owing to @entity158 management and comfort provided, independent of the @entity1 age and the number of core biopsies. We suggest that @entity1340 may also be used in this field to achieve @entity158 management by improving @entity3303 's effect or as an alternative to @entity3303 .
