Reduced Responsiveness to Social Provocation in XXXX Spectrum Disorder.

@entity1 @entity72 @entity2438 @entity146
UNASSIGNED: Deficits in emotion processing and social interaction are prominent symptoms of @entity72 ( @entity72 ). @entity72 has also been associated with @entity146 tendencies towards self and others. The prevalence of @entity146 in this disorder, its etiology and its impact on social life are still unclear. This study investigated behavioral and physiological effects of social provocation in @entity1 with @entity72 and healthy controls. We used a modified Taylor Aggression Paradigm in 24 high-functioning @entity1 with @entity72 and 24 healthy controls. @entity1 were instructed to play against a fictitious @entity1 opponent. Money withdrawals toward the @entity1 represented provocation and money deduction by the @entity1 denoted @entity146 . Throughout the measurement, electrodermal activity (EDA) was recorded. Healthy controls showed higher @entity146 responses to high provocation compared to low provocation, which demonstrated the effectiveness of the used procedure in eliciting @entity146 . @entity1 ' responses were not influenced by the level of social provocation, although in both groups @entity146 was higher after lost compared to won trials. Physiologically, controls showed fewer but higher EDA amplitudes when responding aggressively, whereas @entity1 displayed the opposite pattern of more but lower EDA amplitudes. The modified Taylor Aggression Paradigm successfully elicited @entity146 and revealed different behavioral and neurophysiological responses in @entity1 and healthy controls. @entity1 ' @entity146 as well as their physiological responses were less modulated by level of provocation compared to controls. Therapeutic attempts for @entity1 might concentrate on improving empathic abilities and the understanding of social situations, including provocation and @entity146 . @entity2438 Res 2015.    2015 International Society for @entity2438 Research, Wiley Periodicals, Inc.
