[Macula analysis by spectral domain XXXX in @entity1713 surgery.]

@entity1713 @entity1 @entity32609 @entity6653
INTRODUCTION: Despite surgical reattachment of retinal layers, postoperative functional outcomes after @entity1713 ( @entity1713 ) may be limited. This can be explained by microstructural changes in the macula inherent to the pathology itself as well as the surgery. PURPOSE: To evaluate the various changes in the macula by @entity6653 pre- and postoperatively, and correlate them with functional and clinical outcomes in @entity1 with @entity1713 . To establish pre- and postoperative prognostic factors. METHODS: This was a prospective study of 50 eyes of 50 @entity1 operated for RDD. Each @entity1 underwent a complete clinical examination and macular @entity6653 using the Heidelberg Spectralis; preoperatively and then successively at 7 days, 1 month, 3 months and 6 months after @entity1713 surgery. RESULTS: Preoperative tomographic results revealed an average height of submacular fluid of 742  345 m. Ninety-six percent of @entity1 exhibited thickening of photoreceptor outer segments (PROS), 62% an outer layer undulation, 60% cystic cavities in the outer and/or inner nuclear layers (ONL, INL), 36% disruptions of the external limiting membrane (ELM) and 64% disruption of the IS/OS junction. Postoperatively, 24% of @entity1 had persistent submacular fluid. The average thickness of the central fovea, the ONL, the IS/OS junction and the PROS were 172  51.3 m, 88.4  30.9 m, 11.36  5.4 m and 19.54  13.1 m respectively. Postoperative disruptions of the ELM, the IS/OS junction and Verhoeff's membrane (VM) were present in 24%, 60% and 82% of @entity1 respectively. The preoperative tomographic risk factors for poor visual outcome were: submacular fluid height>800 m (P<0.001), disruptions of the MLE and/or IS/OS junction (P<0.001), as well as cystic cavities in the @entity32609 and/or INL (P=0.002). Postoperative risk factors were: thinning of the fovea ( <=250 m), central fovea ( <=160 m), ONL ( <=90 m), IS/OS junction ( <= 10 m) and PROS ( <=18 m) layers (P<0.001), as well as a discontinuous or absent appearance of the ELM (P<0.001), IS/OS junction (P<0.001) and VM (P=0.006). CONCLUSION: Spectral domain @entity6653 allows detection of specific microscopic, quasi-histologic macular changes in @entity1713 . These anomalies could be predictive of final postoperative visual outcome.
