Xenon-CT study of regional cerebral blood flow around @entity1410 in XXXX with @entity21915 .

@entity1 @entity1009 @entity4 @entity1410 @entity21915 @entity1779
BACKGROUND: Xenon-CT is a quantitive technique for estimating cerebral blood flow. To investigate whether penumbra exists around @entity1410 , regional cerebral blood flow (ICBF) was measured by Xenon-CT in @entity1 with @entity1779 ( @entity1779 ). METHODS: Xenon-CT was performed on 15 @entity1 with @entity21915 and @entity1410 volume < 50 mL. rCBF was measured within 36 h of onset and an average of 13 days later by 27-pixel rings in perihematomal area and its enantiomorph in contralateral hemisphere. Penumbra was defined as rCBF 8-20 mL x 100 g(-1) x @entity1009 ). RESULTS: Average @entity1779 volume was 13 +/- 7 mL (6.4-23.7 mL). First rCBF examination was conducted at 21.7 +/- 9.4 h (5-37 h), second rCBF examination was conducted at 13.4 +/- 1.8 days (11-18 days) after onset. Within 36h of onset, mean perihematomal rCBF was 28.4 +/- 7.8 mL x 100 g(-1) x @entity1009 ); contralateral region was 34.2 +/- 12.2 mL x 100 g(-l) x @entity1009 ) (p = 0.11). Average 13 days after onset, mean rCBF close to @entity1410 was 19.4 +/- 8.1 mL x 100 g(-1) x @entity1009 ); rCBF in contralateral region was 40.1 +/- 11.3 mL x 100 g(-1) x @entity1009 ) (p < 0.0001). rCBF in distal perihematomal region was 27.8 +/- 9.5 mL x 100 g(-1) x @entity1009 ); the difference was significant compared to contralateral region (p = 0.0003). One @entity1 's rCBF in area of @entity4 around @entity1410 was less than 20 mL x 100 g(-1) x @entity1009 ) at first examination. At second examination, 6 @entity1 had same occurrence in region adjacent to @entity1410 and 2 @entity1 experienced it in distal perihematomal region. CONCLUSIONS: Reduced perihematomal rCBF was shown after @entity1779 ; this phenomenon lasted at least 14 days. A number of @entity1779 @entity1 experienced penumbra around @entity1410 .
