Hemodynamics in stented XXXX based on computational fluid dynamics simulations.

@entity1 @entity4798 @entity63 @entity1373 @entity9085 @entity1642
UNASSIGNED: Hemodynamic factors may affect the potential occurrence of in-stent restenosis (ISR) after intervention procedure of @entity9085 ( @entity9085 ). The purpose of the present study is to investigate the influence of stent protrusion length in implantation strategy on the local hemodynamics of the @entity9085 . CTA images of a 58-year-old female @entity1 with @entity4798 transient @entity63 attack were used to perform a 3D reconstruction of the vertebral artery. Five models of the vertebral artery before and after the stent implantation were established. Model 1 was without stent implantation, Model 2-5 was with stent protruding into the subclavian artery for 0, 1, 2, 3  mm, respectively. Computational fluid dynamics simulations based on finite element analysis were employed to mimic the blood flow in arteries and to assess hemodynamic conditions, particularly the blood flow velocity and @entity1642 ( @entity1642 ). The @entity1642 and the blood flow velocity at the vertebral artery ostium were reduced by 85.33 and 35.36% respectively after stents implantation. The phenomenon of helical flow disappeared. Hemodynamics comparison showed that stent struts that protruded 1  mm into the subclavian artery induced the least decrease in blood speed and @entity1642 . The results suggest that stent implantation can improve the hemodynamics of @entity9085 , while stent struts that had protruded 1  mm into the subclavian artery would result in less thrombogenesis and neointimal @entity1373 and most likely decrease the risk of ISR.
