Epidemiology of endemic XXXX : a prospective cohort study in a Peruvian mountain valley community.

@entity1 @entity12357 @entity12358 @entity281 @entity2259 @entity4092
@entity12357 has caused debilitating illness since pre-Incan times, but relatively little is known about its epidemiology. A population-based, prospective cohort investigation was conducted in a Peruvian community with @entity12358 . By use of house-to-house and hospital surveillance methods, cohort @entity1 were monitored for evidence of @entity12358 . Of 690 @entity1 , 0.5% had asymptomatic @entity2259 at study initiation. After 2 years of follow-up, the incidence of @entity281 was 12.7/100 @entity1 -years. The highest rates were in @entity1 <5 years old, and there was a linear decrease in incidence with increasing age. Seventy percent of cases were clustered in 18% of households. Age and @entity12358 in a family member were the best predictors of @entity12357 @entity281 . There were multiple clinical presentations and significant @entity4092 . A cost-effective control strategy should include vector control and surveillance efforts focused on @entity1 and clusters of households with highest endemicity.
