Adhesion study of cultured @entity1 lens capsule cells on hydrophilic intraocular lenses coated with XXXX .

@entity1 @entity20303 @entity231 @entity6456 @entity1358 @entity3677 @entity970 @entity968
PURPOSE: To evaluate the adhesion of @entity1 lens capsule cells on hydrophilic acrylic intraocular lenses (IOLs) coated with @entity968 ( @entity970 ). SETTING: Department of Ophthalmology, Faculty of Medicine, Universidade Estadual Paulista-Botucatu, S  o Paulo, Brazil. DESIGN: Experimental study. METHODS: @entity1 anterior lens capsules obtained during @entity231 surgery were cultured and seeded (200 cells/IOLs) in triplicates on the surface of a copolymer comprising @entity6456 , @entity20303 , and @entity3677 IOLs (Loflex) treated or not treated with @entity970 . After 26 hours, the number of viable adherent cells was estimated by counting in a hemocytometer. RESULTS: The coating of hydrophilic acrylic IOLs with @entity970 was effective in inhibiting cell adhesion (P < .05). Cells showing 2 distinct morphologic patterns-epithelial and dendritic-like-were observed during the in vitro establishment of the cultures. A tendency toward greater adhesion of @entity1358 was observed in untreated IOLs compared with treated IOLs (P = .095). CONCLUSION: Coating hydrophilic acrylic IOLs with @entity970 was effective in inhibiting cell adhesion. This treatment might play a role in posterior capsule opacification prevention. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
