De novo XXXX after pediatric orthotopic liver transplant: a case report.

@entity1 @entity82 @entity294 @entity31 @entity1661 @entity5932 @entity29 @entity1066 @entity1960 @entity618 @entity1140 @entity221 @entity2983 @entity617
OBJECTIVES: The improvement of pre-existing @entity29 after orthotopic liver transplant might be anticipated. However, both the exacerbation of @entity29 and de novo @entity29 after orthotopic liver transplant (despite sufficient allograft immunosuppressive therapy) have been described. MATERIALS AND METHODS: We present a case of @entity31 in a pediatric liver transplant recipient. RESULTS: A 13-year-old @entity1 with cryptogenic liver @entity82 received an orthotopic liver transplant from a deceased donor. Five months later, he presented with watery @entity294 and @entity1661 . He was treated with the immunosuppressive agents @entity1140 (0.15 mg/kg/d) and @entity618 (20 mg/kg/d). A general physical examination revealed a @entity1 with stable vital signs and without @entity221 . The only positive finding was enlargement of the abdomen without tenderness. Many pus cells and a few red blood cells were detected in the @entity1 's stool, but the results of a stool culture for bacteria were negative. Because of his chronic @entity294 , this @entity1 underwent colonoscopy, which revealed @entity5932 , multiple @entity1066 , exudate, and pseudopolyps with a diffuse loss of vascularity. Those findings are indicators of @entity1960 . The results of histopathologic examination of the colonic mucosa suggested @entity31 . The @entity1 was treated with @entity2983 and @entity617 , and a repeat colonoscopy revealed an improvement in his @entity29 . CONCLUSIONS: De novo @entity29 should be considered in @entity1 in whom chronic @entity294 develops after an orthotopic liver transplant. We suggest that colonoscopy and biopsy should always be performed if other causes of @entity294 have been excluded.
