The prevalence of @entity955 in incident XXXX cases and matched population controls in Rochester, Minnesota: changes over three decades.

@entity1 @entity64 @entity955 @entity385
OBJECTIVES: We sought evidence of a change in the prevalence of @entity955 ( @entity955 ) over a 30-year period among residents of Rochester, Minnesota. BACKGROUND: @entity955 is increasingly encountered in clinical practice, but there is limited data on secular trends of @entity955 over time. METHODS: Within a longitudinal case-control study of @entity385 , the prevalence of @entity955 and of selected comorbid conditions among incident @entity64 cases and age- and gender-matched controls between 1960 and 1989 was determined. RESULTS: The mean age +/- standard deviation for the 1,871 @entity64 cases (45% @entity1 ) and matched controls was 75 +/- 11 years. For cases, age-adjusted estimates of @entity955 prevalence for 1960 to 1969, 1970 to 1979, and 1980 to 1989 were 11%, 13%, and 16%, respectively, for @entity1 , and 13%, 16%, and 20% for @entity1 . For controls, the rates were 5%, 8%, and 12%, respectively, for @entity1 , and 4%, 6%, and 8% for @entity1 . Increasing @entity955 prevalence was associated with increasing age (doubling of odds per decade of age in both cases and controls) and calendar time adjusted for age and gender (cases: odds ratio [OR] per 5 years 1.13, 95% confidence interval [CI], 1.05 to 1.22; controls: OR per 5 years 1.24, 95% CI 1.12 to 1.37). The rates of increase with calendar time were significant for cases (p = 0.001) and controls (p < 0.001) and comparable between the genders. CONCLUSIONS: The prevalence of @entity955 increased significantly in @entity385 @entity1 and their controls from 1960 to 1989 in Rochester, Minnesota, independent of age and gender. The rate of increase did not differ significantly between @entity1 and @entity1 .
