Spatial distribution of trabeculae in iliac bone from 145 XXXX females.

@entity1 @entity170 @entity74 @entity3604
145 @entity1 showing clinical and radiological signs of @entity170 of the spine were biopsed at the ilium for histomorphometric analysis of bone mass including trabecular bone volume and parameters reflecting the spatial distribution of bony elements (mean trabecular plate thickness, density and separation). Results were compared with an age-matched population of 22 healthy females. Postmenopausal osteoporotics (i.e. younger than 75 years) were characterized by a significant reduction in trabecular bone volume, plate density and thickness, while senile osteoporotics (i.e. older than 75 years) did not exhibit any difference with controls. 51% of the @entity3604 @entity1 had a trabecular bone volume higher than the spontaneous vertebral crush threshold defined by Meunier. @entity3604 @entity1 with trabecular bone volume under the vertebral crush threshold had a significant decrease in all trabecular parameters. On the opposite, @entity1 with trabecular bone volume above the vertebral crush threshold had only a significant decrease in the number of trabeculae. A negative correlation was found between age and plate density in both @entity3604 @entity1 and controls. A linear correlation was found between trabecular bone volume and plate density, but thickness and density of trabecular plates were not correlated. This study confirms that @entity170 is not only a decreased bone @entity74 . A modified spatial distribution of trabeculae or a mechanically less resistant bone matrix could be additional factors.
