[Studies on XXXX in @entity840 . 1. Clinico-pathological observation].

@entity2700 @entity353 @entity4 @entity7843 @entity840 @entity294 @entity448 @entity1373 @entity281 @entity204
Clinico-pathological and parasitological studies have been performed on spontaneous and experimental @entity7843 in @entity840 . Among 11,244 Hartley @entity840 purchased from suppliers during 1968, 410 (3.6%) of the animals had @entity294 due to @entity7843 . The incidence rate was high in the spring and fall with a mortality rate of 14.4 per cent. A particularly high number of fatal cases were found in the spring. In experimentally induced @entity7843 , clinical signs observed were @entity294 , @entity2700 , @entity353 and @entity204 . The @entity294 developed in all animals on the eleventh day after @entity281 and continued for one to five days. Food and water intakes were markedly reduced after the appearance of @entity294 , followed by @entity448 and @entity2700 . Correlating with the appearance of @entity294 was a striking drop in body weight of the @entity840 . Death usually occurred on the third to fifth day after the onset of @entity294 . The mortality rate was 30 per cent. The major macroscopic findings were characterized by a markedly thickened wall from the ascending to the descending colon and gelatinous @entity4 of the mesenterium of the spiral of the ascending colon. Histologically, there was marked @entity1373 of the mucosal epithelium in the colon and numerous coccidia at different stages of development within the mucus membrane. In the advanced stages of the disease, there was degeneration and desquamation of the epithelia, marked @entity4 of neutrophil leukocytes and lymphocytes into the lamina propria and submucosa, many oocysts in the lumen of the intestine and in the intestinal glands.(ABSTRACT TRUNCATED AT 250 WORDS)
