Pregnancy in XXXX .

@entity1 @entity172 @entity5 @entity935 @entity442 @entity2124 @entity2012 @entity4611 @entity1943 @entity9045
UNASSIGNED: With advances in surgical and medical treatment and the availability of assisted reproductive techniques, pregnancy in @entity1 with @entity2012 is more frequently encountered. Diagnosis of @entity2012 during pregnancy is difficult because of changes in @entity2124 and insulin like growth factor-1 ( @entity442 ) axis secondary to placental production of @entity2124 . The difficulty is compounded by the inability of routine hormone assays to detect placental @entity2124 . In the majority of @entity1 with @entity2012 , pregnancy does not have an adverse effect on mother or fetus and pituitary mass does not increase in size. The level of @entity442 usually remains stable because of the effect of @entity172 causing a @entity2124 resistant state. In @entity1 with @entity4611 , the possibility of an increase in size of the pituitary mass needs to be kept in mind and more frequent monitoring is required. In case of @entity5 enlargement, pituitary surgery can be considered in the mid trimester. Experience with the use of medical treatment for @entity2012 during pregnancy is increasing. @entity935 agonists, @entity1943 analogs or @entity9045 antagonists have been used without any adverse consequences on mother or fetus. At present, it is advisable to stop any medical treatment after confirmation of pregnancy till more data are available on the safety of these drugs.
