Impact of left ventricular ejection fraction and medication adherence on major adverse XXXX during the first year after successful primary percutaneous coronary interventions.

@entity1 @entity453 @entity299
AIMS AND OBJECTIVES: To identify the impact of preprocedural left ventricular ejection fraction and adherence to prescribed medication on major adverse @entity299 in @entity1 with a successful primary percutaneous coronary intervention. BACKGROUND: Although advances in percutaneous coronary intervention for @entity453 have considerably reduced poor outcomes such as major adverse @entity299 , many @entity1 still experience adverse outcomes after a percutaneous coronary intervention. Thus, in @entity1 with percutaneous coronary intervention, it is extremely important to identify the predictors for major adverse @entity299 . DESIGN: A retrospective and cross-sectional design. METHODS: Three hundred and nineteen @entity1 who underwent successful primary percutaneous coronary intervention participated in this study. @entity1 were assessed for major adverse @entity299 after percutaneous coronary intervention for the first year. Preprocedural left ventricular ejection fraction was measured by echocardiogram. Medication adherence was used with the validated Morisky Medication Adherence Scale-8 items at the first year after the successful primary percutaneous coronary intervention. RESULTS: Of the 319 @entity1 , 102 had major adverse @entity299 after the successful primary percutaneous coronary intervention. On the basis of Cox regression, after adjusting for @entity1 characteristics, lower baseline left ventricular ejection fraction and medication nonadherence and were statistically significant and independent predictors of major adverse @entity299 . CONCLUSIONS: Our results show that major adverse @entity299 after successful primary percutaneous coronary intervention are associated with low left ventricular ejection fraction at baseline and medication nonadherence after discharge. Therefore, healthcare providers should consider multidimensional approaches to improve low left ventricular ejection fraction and medication adherence. RELEVANCE TO CLINICAL PRACTICE: The findings suggest that the classification of high-risk @entity1 after percutaneous coronary intervention need to be based on level of preprocedural left ventricular ejection fraction. Follow-up of these @entity1 may include educational interventions to enhance medication adherence, to decrease the prevalence of major adverse @entity299 .
