Impact of Sleep and Circadian Disruption on Energy Balance and XXXX : A Summary of Workshop Discussions.

@entity1 @entity8 @entity6 @entity25 @entity1353 @entity28 @entity19 @entity2690 @entity27 @entity413
ABSTRACT: A workshop was held at the National Institute for @entity6 and Digestive and @entity8 with a focus on the impact of sleep and circadian disruption on energy balance and @entity6 . The workshop identified a number of key principles for research in this area and a number of specific opportunities. Studies in this area would be facilitated by active collaboration between investigators in sleep/circadian research and investigators in metabolism/ @entity6 . There is a need to translate the elegant findings from basic research into improving the metabolic health of the American public. There is also a need for investigators studying the impact of sleep/circadian disruption in @entity1 to move beyond measurements of @entity2690 and @entity413 and conduct more in-depth phenotyping. There is also a need for the assessments of sleep and circadian rhythms as well as assessments for @entity25 @entity1353 to be incorporated into all ongoing cohort studies related to @entity6 risk. Studies in @entity1 need to complement the elegant short-term laboratory-based @entity1 studies of simulated short sleep and shift work etc. with studies in subjects in the general population with these disorders. It is conceivable that chronic adaptations occur, and if so, the mechanisms by which they occur needs to be identified and understood. Particular areas of opportunity that are ready for translation are studies to address whether CPAP treatment of @entity1 with @entity27 (OSA) prevents or delays the onset of @entity6 and whether temporal restricted feeding has the same impact on @entity28 rates in @entity1 as it does in @entity19 .
