XXXX in renal transplant recipients: Prevalence, predictors of occurrence and genetic characterization.

@entity1 @entity3753 @entity8 @entity1496 @entity16254 @entity24516 @entity294 @entity791 @entity7014
PURPOSE: @entity24516 , which occurs in immunocompromised states such as @entity791 , has rarely been studied in @entity1 with @entity8 ( @entity8 ) on immunosuppressive therapy. MATERIALS AND METHODS: Three hundred and twenty-four consecutive @entity8 recipients on immunosuppressive treatment and 170 healthy subjects were evaluated for @entity24516 and other parasites by modified trichrome staining, wet mount using normal saline, @entity1496 and polymerase chain reaction (PCR). Clinical, demographic and laboratory parameters associated with occurrence of @entity24516 were studied using univariate and multivariate analysis. The species of microsporidia were studied using PCR-restriction fragment length polymorphism (RFLP). @entity1 were treated with @entity3753 (400 mg twice daily for 2 weeks). RESULTS: Of 324 @entity8 recipients initially screened, 52 were excluded from final analysis due to incomplete data. @entity1 with @entity8 [n = 272, age 42    12.54 years, 222 (81.6%) male] more often had @entity24516 than healthy subjects by modified trichrome stain and PCR [n = 170, age 33.8    6.7 years, 123 (72.3%) male] [16/272 (5.8%) vs. 0/170 (0%), P < 0.001]. @entity1 with @entity24516 were younger (33.9    8.3 years vs. 42.3    12.6 years; P = 0.009), had @entity294 more often (13/16, 81% vs. 123/256, 48%; P = 0.02), which was longer in duration (60, 32.5-105 days vs. 12, 6.2-18 days; P < 0.001) and had associated @entity7014 (2/16, 12.5% vs. 2/256, 0.8%; P = 0.018). Younger age, presence of @entity294 and associated @entity7014 were significant on multivariate analysis. @entity16254 was detected in 15/16 (93%) @entity1 with @entity24516 . CONCLUSION: @entity24516 occurs frequently in @entity1 with @entity8 on immunosuppressive treatment, particularly among younger @entity1 with @entity294 and associated @entity7014 . @entity16254 is the major species identified among these @entity1 .
