Postpartum XXXX in Mid Glamorgan.

@entity1 @entity1375 @entity1669 @entity1378 @entity1374
A high prevalence of postpartum @entity1374 has been reported in several countries, but there have been no systematic studies of its prevalence in Britain. Among a group of 901 consecutive, unselected pregnant @entity1 thyroid autoantibodies were detected in 117 (13%) at booking. The clinical course of postpartum @entity1374 , factors associated with its development, and its likely prevalence were defined in 100 of these @entity1 with thyroid antibodies and 120 @entity1 with no such antibodies who were matched for age. None of the @entity1 had a history of @entity1669 . Normal reference ranges for thyroid function during pregnancy and post partum were established in the 120 @entity1 negative for thyroid antibodies. On the basis of these observations postpartum @entity1374 was observed in 49 (22%) of the 220 @entity1 studied, and the prevalence in the total group of 901 @entity1 was estimated to be 16.7%. @entity1374 , mainly occurring in the first six months post partum, was usually transient and included both destruction induced @entity1378 and @entity1375 . The development of the syndrome was significantly related to smoking more than 20 cigarettes a day and the presence of thyroid microsomal autoantibodies at booking. Of the 16 @entity1 with a family history of @entity1374 in whom thyroid microsomal autoantibody activity was detectable at booking, 11 developed @entity1374 . Age, parity, presence of goitre at presentation, duration of breast feeding, and the sex and birth weight of the @entity1 were not associated with the development of postpartum @entity1374 . The mood changes experienced by @entity1 post partum may in part be associated with altered thyroid function during this time.
