[Coxsackie XXXX infections in cardiology. Apropos of 66 cases].

@entity1 @entity22421 @entity384 @entity2396 @entity71027 @entity741 @entity299 @entity583 @entity65
Coxsackie @entity22421 infections are common and frequently asymptomatic. However in young @entity1 , they can cause primary @entity384 and complicate previous @entity65 . Virus diagnosis is difficult and based mainly on the detection of significant rising or stating high neutralizing antibody titers. A clinical and epidemiological five years study investigated 3,856 sera. 30.2% of the @entity1 had evidence of a significant antibody titer (greater than or equal to 64) to one of the group B Coxsackie viruses; this percentage reaches 34.6% in cardiology and fluctuates from year to year; Coxsackie B2 is predominant (55.9%) in cardiology; coxsackie B1 and B2 antibody responses were detected more frequently than @entity71027 . Coxsackie B6 appears to be uncommon. From these, 66 @entity1 have evidence of coxsackie @entity22421 infections with 60.2% for Coxsackie B2; they include @entity2396 (30.3%), acute and chronic @entity384 (19.7%). Moreover it has been suggested that Coxsackie @entity22421 might be responsible for electrocardiographic abnormalities (9.1%), @entity741 and @entity583 . Enzyme linked immunosorbent assay (ELISA) and radioimmunoassay with purified antigens (VP1 and VP4) did not appear better than microneutralisation for evaluation of IgM and IgG antibodies. To elucidate the mechanisms of @entity299 it is refer to viral replication, virus specific and auto-reactive T cells cytotoxic activities.
