Low XXXX to @entity1426 ratio is associated with thin-cap @entity1856 determined by optical coherence tomography.

@entity1 @entity7784 @entity8393 @entity1187 @entity1426 @entity1856
BACKGROUND: A low @entity7784 ( @entity8393 )/ @entity1426 (AA) ratio is known to be associated with cardiovascular events. However, the relationship between the @entity8393 /AA ratio and coronary plaque vulnerability assessed by optical coherence tomography (OCT) has not been examined thoroughly. This study examined the relationship between the @entity8393 /AA ratio and coronary plaque vulnerability assessed by OCT in @entity1 with @entity1187 ( @entity1187 ). METHODS: We evaluated 59 @entity1187 @entity1 who had undergone percutaneous coronary intervention using OCT. We divided them into 2 groups according to OCT findings-those with and without thin-cap @entity1856 (TCFA)-and compared the @entity8393 /AA ratio between the groups. RESULTS: We identified 32 and 27 @entity1 with and without TCFA, respectively. The @entity8393 /AA ratio was significantly lower in @entity1 with TCFA than in those without TCFA [0.35, interquartile range (0.21-0.44) vs. 0.54, interquartile range (0.42-0.70); p<0.001]. In multivariate logistic regression analysis, the @entity8393 /AA ratio was an independent predictor of TCFA (odds ratio, 0.09; 95% confidence interval, 0.007-0.99; p=0.049). The @entity8393 /AA ratio and fibrous cap thickness showed a significant positive correlation (Spearman   =0.46; p<0.001). Furthermore, receiver operating characteristic curve analysis showed that an @entity8393 /AA ratio<0.46 could predict TCFA (81.3%, sensitivity; 74.1%, specificity). CONCLUSIONS: A low serum @entity8393 /AA ratio is significantly associated with coronary plaque vulnerability assessed by OCT in @entity1187 @entity1 .
