[Liver function in @entity1707 during general anesthesia induced by intravenous administration of XXXX , nembutal, eunarcon and brevinarcon].

@entity1707 @entity8600 @entity648 @entity519 @entity22292 @entity8019 @entity413
The investigations were carried out on 120 healthy @entity1707 , aged from 3 to 7 months, weighing from 40 to 70 kg. The @entity1707 were divided into 5 groups, 12 animals in each;, according to the agents administered intravenously. A similar arrangement of groups was adopted to determine the degree of @entity8600 retention. Group I served as control. Blood was collected from the anterior vena cava after 1 hour and 1, 3 and 7 days since the moment of administration of physiological solution (group I) or since the appearance of general anaesthesia (groups II-V). The following determinations were made in serum: content of total protein and protein fractions; activity of AspAT, AlAT and @entity8019 ; @entity648 and retention of @entity8600 ; content of @entity413 in blood. The results were analysed statistically by determining the mean, the standard deviation and the test of significance t Student. The investigations resulted in the following conclusions. Anaesthesia produced in healthy @entity1707 by the 4 preparations leads to considerable functional disturbances in the liver, expressed by increased activity of AspAT, AlAt and @entity8019 , decreased albumin content, increased content of gamma globulins, and increased retention of @entity8600 . The greatest changes were observed after @entity22292 and Nembutal. After Eunarcon, the changes were fairly high, but of short duration. The slightest and most transient disturbances were found after Brevinarcon. These results make it possible to conclude that the functional disturbances of the liver after general anaesthesia are due to @entity519 of this organ. In the present experiment, such disturbances were reversible, i.e. they receded after 7 days.
