Evaluation of the effectiveness of a home-based inspiratory muscle training programme in XXXX with @entity1030 using multiple inspiratory muscle tests.

@entity1 @entity308 @entity4589 @entity13091 @entity148 @entity1576 @entity1030
PURPOSE: To evaluate the effectiveness of a home-based inspiratory muscle training (IMT) programme using multiple inspiratory muscle tests. METHOD: Sixty-eight @entity1 (37   M) with moderate to severe @entity1030 ( @entity1030 ) (Mean [SD], FEV1 36.1 [13.6]% pred.; FEV1/FVC 35.7 [11.2]%) were randomised into an experimental or control group and trained with a threshold loading device at intensity >30% maximum inspiratory pressure (PImax) or <15% PImax, respectively, for 7 weeks. Thirty-nine @entity1 (23   M) completed the study. The following measures were assessed pre- and post-IMT: PImax, sniff inspiratory nasal pressure (SNIP), diaphragm contractility ( @entity13091 ,tw), incremental shuttle walk test (ISWT), @entity4589 ( @entity4589 ), chronic @entity1576 questionnaire (CRDQ), the hospital @entity148 and @entity308 scale (HADS) and the SF-36. Between-group changes were assessed using one-way analysis of variance (ANOVA). RESULTS: PImax and perception of well-being improved significantly post-IMT [p   =   0.04 and <0.05 in four domains, respectively]. This was not reflected in SNIP [p   =   0.7], @entity13091 ,tw [p   =   0.8], @entity4589 [p   =   0.9] or ISWT [p   =   0.5]. CONCLUSIONS: A seven-week, community-based IMT programme, with realistic use of health-care resources, improves PImax and perception of well-being but a different design may be required for improvement in other measures. Multiple tests provide a more comprehensive evaluation of changes in muscle function post-IMT. Implications for Rehabilitation A seven-week, home-based inspiratory muscle training programme improves maximal inspiratory pressure and perception of well-being in @entity1 with moderate to severe @entity1030 but not sniff nasal inspiratory pressure or diaphragm contractility, @entity4589 and exercise capacity. Multiple tests are recommended for a more comprehensive assessment of changes in muscle function following inspiratory muscle training programmes. Therapists need to explore different community-based inspiratory muscle training regimes for @entity1030 @entity1 and identify the optimal exercise protocol that is likely to lead to improvements in diaphragm contractility and exercise capacity.
