Postoperative radiotherapy is effective for XXXX but not for @entity5 : the Japanese Association for Research on the Thymus Database Study.

@entity1 @entity4557 @entity704 @entity5 @entity1349 @entity34
BACKGROUND: The efficacy of postoperative radiotherapy (PORT) for thymic @entity5 is still controversial. Using the Japanese Association for Research on the Thymus (JART) database, this study was aimed at clarifying the efficacy of PORT for @entity5 and @entity704 . METHODS: The JART database registered the records of 2835 @entity1 collected from 32 Japanese institutions from 1991 to 2010. @entity704 and @entity704 at stage II or III were extracted. The efficacy of PORT with respect to @entity4557 ( @entity4557 ) and @entity1349 ( @entity1349 ) was evaluated with the Kaplan-Meier method and Cox regression analysis. RESULTS: There were 1265 @entity1 in all: 155 @entity704 cases (12.3%) and 1110 @entity704 cases (87.7%). Eight hundred ninety-five (70.8%) were at stage II, and 370 (29.2%) were at stage III. Four hundred three cases (31.9%) underwent PORT. PORT for @entity5 was associated with increasing @entity4557 (hazard ratio, 0.48; 95% confidence interval, 0.30-0.78; P =   .003) but was not associated with @entity1349 (hazard ratio, 0.94; 95% confidence interval, 0.51-1.75; P =   .536). PORT for @entity34 was not associated with @entity4557 or @entity1349 (P =   .350). A subgroup analysis of stage III @entity704 showed no factor associated with the efficacy of PORT. CONCLUSIONS: In this study, PORT did not increase @entity4557 or @entity1349 for @entity34 but increased @entity4557 for @entity5 .
