Clinical applicability of @entity1 in vivo localized @entity3151 -31 magnetic resonance spectroscopy of XXXX .

@entity5 @entity3151 @entity1 @entity2721
BACKGROUND: Magnetic resonance imaging (MRI) is of restricted value for the in vivo characterization of @entity5 types. The applicability of @entity3151 -31 (31P) magnetic resonance spectroscopy (MRS) in the diagnosis of @entity2721 is unknown. METHODS: A total of 191 consecutive @entity1 (85 females and 106 males; mean age 41 years, range 1-80) with @entity2721 on MRI were analyzed for additional 31P spectroscopy. Histology and/or cytology was obtained from all @entity5 . Because of low sensitivity of the 31P nucleus and the contamination of surrounding tissue, only large, superficially located @entity5 accessible to the surface coil could be accepted for MRS. RESULTS: Twenty-one @entity1 (11%) could be included in the study. From this remaining group only 12 studies (57%) produced spectra with well resolved @entity3151 peaks and an acceptable signal-to-noise ratio. However, these spectra did not allow differentiation between the benign and malignant nature of the lesions. The other 9 studies showed spectra with poor signal intensities and/or poorly defined peaks, making @entity5 differentiation impossible. CONCLUSION: Only 6% of the @entity2721 produced well defined spectra, which implies that localized 31P MRS cannot be considered as a routine technique in the diagnostic and treatment evaluation of @entity2721 .
