A systematic review of XXXX : frequency and prognosis after @entity510 .

@entity1 @entity244 @entity548 @entity510
OBJECTIVE: To review systematically the frequency and prognostic significance of @entity548 in @entity1 with @entity510 ( @entity244 ). METHODS: Papers relating to @entity548 in @entity1 with @entity510 were retrieved. The only studies considered were those with at least 10 consecutive cases of @entity510 with or without @entity548 . The frequency of @entity548 in such cases was calculated in prospective and retrospective studies. Mortality was compared in @entity1 with and without @entity244 . RESULTS: 154 papers were reviewed. Three prospective studies and six retrospective studies satisfied the inclusion criteria. Of 181 @entity1 with @entity510 assessed prospectively (mean age, 51.7 years), 24 (13%) had @entity548 ; among 1086 retrospective records, 37 (3%) had documented @entity548 (p<0.001). @entity1 with @entity244 had higher Hunt and Hess grades than those without (mean grade, 3.6 v 2.6). @entity1 with @entity244 were also more likely to die (13 of 30 (43%) v 31 of 342 (9%); odds ratio 4.8; p<0.001). CONCLUSIONS: Prospective studies show a higher frequency of @entity244 than retrospective studies, suggesting that @entity548 is not well documented. @entity548 is an adverse prognostic finding in @entity1 with @entity510 .
