[Undifferentiated nasopharyngeal carcinoma in adolescent and XXXX ].

@entity5 @entity1 @entity10 @entity2802
@entity5 with nasopharyngeal primary location are relatively rare in @entity1 . One of the most frequent paediatric @entity5 in this region is the undifferentiated @entity5 (UCNT). These @entity5 are usually revealed by nasal obstruction, @entity10 or cervical nodal involvement. The nasopharyngeal mass can be discovered during an ear-nose and throat examination and confirmed after medical imaging investigation. Diagnostic is obtained by nasopharyngeal mass or cervical nodal biopsy. This @entity5 has a high chemo and radio-sensibility in @entity1 . Irradiation of the cavum and the nodes areas remains as the reference treatment of this disease. Most paediatric protocols add chemotherapy to radiotherapy. The value of concomitant or adjuvant chemotherapy is still debated in paediatric population. It was shown that the T and N staging at diagnosis determined by the classification @entity2802 is a major prognostic factor. Due to the importance of the loco-regional sequelae after irradiation and the satisfactory global prognosis, the actual trend is a decrease in the total dose of irradiation delivered, particularly for @entity1 with a good response to first chemotherapy. This article sheds light on the particularities of UCNT in paediatric @entity1 .
