Borderline @entity101 : relationship between age, hemodynamics and circulating XXXX .

@entity1 @entity101 @entity935 @entity1425 @entity2661 @entity1063
The relationships between age, systemic and renal hemodynamics, circulating @entity2661 ( @entity1063 , @entity1425 and @entity935 ) and intravascular volumes were studied in 38 normotensive subjects and in 77 @entity1 with borderline essential @entity101 . Borderline @entity101 @entity1 had a higher cardiac index (p less than 0.02) and renal blood flow (p less than 0.05) than normotensive subjects if they were younger than 30 years of age, whereas in older @entity1 no difference was observed. In contrast, total peripheral resistance was normal in young borderline @entity101 @entity1 , but significantly increased (p less than 0.02) in @entity1 older than age 40 years. Cardiac output (r = -0.28, p less than 0.01) and renal blood flow (r = -0.47, p less than 0.001) correlated inversely with age in the entire population and in both subgroups. Cardiac output also correlated closely with renal blood flow in all subjects (r = 0.45, p less than 0.001). Circulating @entity1063 levels increased with age (r = 0.25, p less than 0.05), whereas @entity1425 concentration tended to decrease. Plasma and total blood volume correlated directly with cardiac output (r = 0.39, p less than 0.001) and inversely with peripheral resistance (r = -0.34, p less than 0.001). These data indicate that the hyperdynamic circulation (high cardiac output and renal blood flow) of borderline @entity101 is found predominantly in @entity1 younger than age 30 years. Older @entity1 are characterized by an elevated total peripheral resistance and normal cardiac output. The age-dependent increase in circulating @entity1063 and decrease in @entity1425 levels may participate in the shift of the hemodynamic profile from high-cardiac-output @entity101 in the young to a high-arteriolar-resistance @entity101 in the older @entity1 .
