Large bowel XXXX containing @entity189 --a diagnostic and therapeutic approach.

@entity1 @entity5 @entity189 @entity3 @entity14 @entity652
@entity652 containing @entity189 of the large bowel form the majority of early @entity14 . Conclusive histological diagnosis of early @entity14 depends on two conditions; first, the whole lesion must be examined and second the resection margin must border on healthy tissue. The presence of certain histopathological features makes it possible to distinguish between cases with high and low risk of having lymph node @entity3 . Sixty-six @entity652 containing @entity189 are reported. They comprised 3.15% of 2,095 @entity652 removed by colonoscopic polypectomy during the same period. Five cases were lost to follow-up. Forty-nine @entity1 considered to be at low risk of having lymph node @entity3 have been treated by endoscopic polypectomy only with a rigorous follow-up regime including CEA estimation, ultrasonography and total colonoscopy at regular intervals. In none have distant @entity3 been found on follow-up examinations at a mean duration of 3 years. Two of these cases have developed a metachronous @entity14 and 15 (30.5%) have metachronous @entity652 . Two low risk @entity1 with no @entity5 found in the operative specimen have undergone major surgical resection. Ten high risk cases have been referred for major surgery and lymph node @entity3 have been found in four (40%). The need for careful histological examination for lymphatic and veinous invasion is stressed by the presence of this finding in all four high risk @entity1 with involved lymph nodes.
