[Anxio- XXXX Syndrome - Biopsychosocial Model of Supportive Care].

@entity1 @entity308 @entity5 @entity73 @entity935 @entity409 @entity1295 @entity3085 @entity1005 @entity5539 @entity148 @entity158 @entity750 @entity4696 @entity25 @entity774
BACKGROUND: Acute stress in @entity1 experiencing @entity5 diagnosis and the @entity1005 in @entity5 survivors results in impaired overall quality of life mainly due to associated psychological and physical alterations, including @entity148 , @entity308 , @entity25 , @entity73 , @entity1295 , @entity158 , @entity3085 and others. Recent studies revealed a new insight into molecular mechanisms contributing to the development of @entity5 . It has been shown that adverse psychosomatic reactions including @entity5 @entity5 result from @entity409 , disruption of the @entity774 and sympathetic nervous system, @entity750 - @entity935 interactions and circadian sleep-wake rhythm disruption. AIM: The aim of the present study was to evaluate clinical studies oriented toward elucidation of the hypothesis that @entity5 is the @entity4696 leading to the development of accompanying @entity5539 . MATERIAL AND METHODS: The data of the biopsychosocial approach in the treatment of @entity5 presented in the current literature were collecting using appropriate electronic databases and were elaborated in the form of meta-analysis of 24 selected publications. RESULTS: According to relevant clinical studies, psychosocial interventions and psychopharmacological treatment has been shown to reduce @entity5 symptomatology and to improve the ability of @entity1 to cope with the disease. Thus, one of the key pillars of supportive care in oncology is stress reduction. Cognitive-behavioral interventions and group psychosocial therapies have shown to reduce stress from the diagnosis and treatment, to palliate @entity308 and to help in restoring the circadian rhythm. Psychopharamacological interventions are the most useful approaches in the reduction of stress-induced @entity5 comorbidities. In the presented study, a plausible role of stress reduction in the protection of @entity5 @entity1 from posttraumatic and @entity308 , physical and psychical suffering, from decrease of @entity1 quality of life, ability to cope with the disease and cooperate in @entity5 treatment has been analyzed. CONCLUSION: Implementation of the biopsychosocial model of @entity5 care needs further cooperation between behavioral scientists and clinical oncologists attempted to elucidate further possibilities of psychosocial and pharmacological interventions leading to the regulation of stress-induced alterations of the neurotransmitter system and @entity409 reduction of @entity5 and improvement of @entity1 survival time.Key words: @entity5 - behavioral risk profile - @entity308 - @entity409 - psychosocial and pharmacological intervention The authors declare they have no potential conflicts of interest concerning drugs, products, or   services used in the study. The Editorial Board declares that the manuscript met the ICMJE "uniform requirements" for biomedical papers.Submitted: 30. 7. 2014Accepted: 8. 4. 2015.
