Clinical and Pathologic Factors Predictive of Positive Radiologic Findings in High-Risk XXXX .

@entity1 @entity3329 @entity957 @entity5
BACKGROUND: At present, there exists considerable clinical uncertainty regarding the role of radiologic imaging in the staging and management of high-risk @entity957 (hrSCC). OBJECTIVE: The authors sought to investigate the clinical and pathologic features predictive of bony invasion, perineural invasion, or @entity3329 in @entity1 that had undergone head and neck imaging for hrSCC. MATERIALS AND METHODS: The authors conducted a single-center retrospective chart review of @entity1 (n = 82) that had undergone head and neck imaging for hrSCC. RESULTS: Twenty-nine percent (24/82) of @entity1 in the study had positive findings on radiologic imaging. Immunocompromised @entity1 were more likely to have the radiologic finding of @entity3329 (p = .04). @entity5 size was found to correlate with the radiologic finding of bony invasion (correlation coefficient = 0.40, p = .0002). There was no relationship between either high risk location or high risk histopathology and positive radiologic findings. The low number of @entity1 and its retrospective nature are study limitations. CONCLUSION: The clinical features of host immunosuppression and @entity5 size are predictive of positive imaging findings in hrSCC. The decision to perform radiologic imaging in @entity1 with hrSCC may be influenced by these factors, but continue to be more firmly guided by physical exam and clinical suspicion.
