Neonatal XXXX : 444 Cases in 7 Years.

@entity1 @entity410 @entity4008 @entity5125 @entity693 @entity1892 @entity3631 @entity166 @entity526
BACKGROUND: Neonatal @entity4008 remains a severe @entity166 with mortality rates varying between 10% and 15%. The clinical and bacteriologic features of @entity693 collected from January 2001 to December 2007 in a French national survey are presented here. METHODS: Cases of @entity693 were prospectively collected by a network of 252 pediatric wards covering 61% of French pediatric wards, associated with 168 microbiology laboratories. @entity693 was classified as early-onset (d0-d4) and late-onset (d5-d28). Statistical analyses were performed according to gestational age and weight at birth. RESULTS: A total of 444 cases of neonatal @entity4008 were reported by 114 pediatric wards. Five cases were excluded from analysis. @entity1892 ( @entity1892 ) and @entity526 accounted respectively for 59% and 28% of the cases, followed by Gram-negative bacilli other than @entity526 (4%), other streptococci (4%), @entity3631 (3%), and @entity5125 (1.5%). @entity1892 was the most common pathogen both in early-onset (77% vs. 18% for @entity526 ) and in late-onset @entity693 (50% vs. 33% for @entity526 ). Among preterm @entity1 , @entity526 was more commonly isolated (45% vs. 32% for @entity1892 ), especially in very preterm @entity1 (54%). @entity1892 was more often involved in @entity410 than @entity526 (41% vs. 25%). The overall mortality rate was 13% but reached 25% in preterm or small for gestational age @entity1 , regardless of the etiology. CONCLUSIONS: @entity1892 was the dominant cause of neonatal @entity4008 , with 77% of early-onset and 50% of late-onset cases. @entity526 was the most common bacteria in preterm @entity1 .
