Stereotactic biopsy for multifocal, diffuse, and deep-seated XXXX using Leksell's system.

@entity1 @entity410 @entity706 @entity1313 @entity75 @entity5 @entity39 @entity548 @entity11
Using the Leksell stereotactic system, we selectively performed 91 biopsies for surgically inaccessible @entity75 . There were 25 multiple (27.5%), 15 diffuse (16.5%), and 51 (56.0%) @entity75 . However, we avoided subjecting the @entity1 with lesions adjacent to major vascular trunks or complex vascular structures such as the cavernous sinus, peri-insular regions and the pineal regions to stereotactic biopsy. The diagnosis was histologically confirmed in 84 cases (92.3%). Sixty-nine (75.8%) lesions were @entity5 ; 44 (48.4%) were @entity11 , 18 (19.8%) @entity706 , and five (5.5%) low-grade @entity11 . Thirteen (14.3%) cases had previously undergone radiation and/or chemotherapy for @entity1313 , seven had recurrent @entity11 (five with malignant transformation) and six manifested radiation @entity39 . None of the @entity1 died due to the stereotactic procedure; one (1.1%) exhibited morbidity due to complicated @entity548 . We found asymptomatic @entity548 occurred in nine (9.9%) @entity1 ; the rate of @entity548 was significantly higher in @entity1 with preoperative angiographic evidence of @entity5 stain. Two @entity1 (2.2%) suffered @entity410 , in one case @entity410 was induced by electric stimulation test at the target site. All five @entity1 younger than 15 years underwent the procedure without complications. The Leksell stereotactic system is useful for diagnostic tissue sampling and contributes effectively to the selection of appropriate therapy in @entity1 with malignant @entity1313 . While it carries a low morbidity rate without mortality in our series, care must be taken for selected target sites in highly vascularized lesions exhibiting positive @entity5 stains.
