Surgery with intraoperative radiotherapy for XXXX of the pelvic girdle: a pilot experience.

@entity1 @entity66 @entity242 @entity5 @entity3 @entity2530
@entity242 of the pelvic girdle represent difficult treatment problems. Many are not treatable for cure, and among the @entity1 who are technically resectable, there is high risk for @entity5 recurrence and distant spread. Intraoperative radiotherapy (IORT) has been used in conjunction with surgical resection in five @entity1 with extensive @entity242 of the pelvic girdle. @entity1 underwent a hemipelvectomy and IORT (dose 20-30 Gy) to the sacral resection margin and surrounding soft tissues. Three @entity1 developed pulmonary @entity3 within 3 months and eventually died from metastatic disease (8-38 months). Two @entity1 have remained disease-free (43 and 53 months). Four @entity1 (80%) have remained locally free of @entity5 with follow-ups of 8-53 months. The only treatment complication was late @entity2530 of the coccyx which appeared 7 months after treatment. By contrast, six historical control @entity1 with @entity242 of the pelvic girdle treated with resection alone showed a local control rate of only 27% over a 40-month follow-up. On the basis of this preliminary experience, it appears that IORT may substantially help to control @entity66 in @entity1 with grossly resectable @entity242 of the bony pelvis.
