Outcome of regional lymph node dissection in conjunction with laparoscopic nephroureterectomy for XXXX of the upper urinary tract.

@entity5 @entity1 @entity1803 @entity189
OBJECTIVE: To obtain accurate disease @entity5 , we routinely perform regional lymph node dissection (LND) in conjunction with laparoscopic nephroureterectomy (NU) to treat @entity189 of the upper urinary tract. The present study evaluated the feasibility and usefulness of LND in laparoscopic NU. @entity1 AND METHODS: Thirty-nine @entity1 undergoing laparoscopic NU with regional LND were included in the present study. We evaluated the number of lymph nodes (LNs) resected, pathological node status, adverse events, and survival data. Node count was compared with that of 41 @entity1 who underwent open NU between 1990 and 2008. RESULTS: The median number of LNs removed was 10 (range, 2-59) in the laparoscopic NU group and 10 (range, 1-65) in the open NU group (Mann-Whitney U-test, p   =   0.82). Pathological examination demonstrated positive LNs in four @entity1 (10.3%) and three of the four @entity1 received adjuvant chemotherapy. Although chylous drain discharge was detected just after resuming dietary intake in eight @entity1 , it resolved without significant problem. Five-year overall survival by stage was 100% for pT2 >=  disease, 55% for @entity1803 disease, and 0% for pT4 disease. CONCLUSIONS: LND can be performed safely and effectively during laparoscopic nephroureterectmy. We consider that accurate node @entity5 and subsequent stratification are mandatory for disease management.
