Prevalence and predictors of affective lability after paediatric XXXX .

@entity1 @entity131 @entity146 @entity75 @entity71 @entity148 @entity130
OBJECTIVE: Paediatric severe @entity131 ( @entity131 ) is associated with significant @entity130 affective and behavioural problems. Few studies have examined the prevalence and characteristics of affective lability after paediatric @entity131 . METHODS: Ninety-seven @entity1 with severe @entity131 were evaluated 1 year @entity130 for the presence of affective lability using the @entity1 's Affective Lability Scale (CALS). Demographic, clinical and @entity75 characteristics were also assessed. RESULTS: Affective lability significantly increased after injury. Eighty-six @entity1 had a pre-injury CALS score of 1 SD or less from the group pre-injury mean (M   =   8.11, SD   =   9.31), of which 35 and 15 @entity1 had a 1 SD and 2 SD increase in their CALS score from pre- to @entity130 , respectively. A variety of affective shifts manifested @entity130 including @entity148 , silliness, dysphoria and @entity146 . The most severe symptoms were @entity146 and unpredictable temper outbursts. Risk factors for affective lability included elevated pre-injury affective lability and psychosocial adversity as well as greater damage to the orbitofrontal cortex. Post-injury affective lability was most frequently associated with a @entity130 diagnosis of @entity71 . CONCLUSIONS: Affective lability is common after paediatric @entity131 and frequently manifests as @entity146 and unpredictable outbursts. Early intervention is needed to improve @entity146 outcomes.
