Evaluation of XXXX level in gingival crevicular fluid in periodontal health, in @entity7278 and after nonsurgical periodontal therapy: A clinicobiochemical study.

@entity1 @entity9492 @entity7278 @entity26 @entity2041 @entity6172 @entity2521
CONTEXT: @entity2521 is predominantly due to exaggerated host response to pathogenic microorganisms and their products which causes an imbalance between the reactive @entity26 species-antioxidant in gingival crevicular fluid (GCF). @entity2041 is an important redox regulator in GCF and maintenance of stable @entity2041 ( @entity6172 ): @entity9492 ( @entity9492 ) ratio is essential for periodontal health. AIMS: The present study was undertaken to evaluate and compare the level of @entity2041 and redox balance ( @entity6172 : @entity9492 ratio) in GCF of @entity7278 @entity1 , periodontally healthy controls and also to evaluate the effect of nonsurgical periodontal therapy on the level of @entity2041 and redox balance during 3 months postoperative visit. STUDY DESIGN: Baseline GCF samples were collected from 20 @entity7278 @entity1 and 20 periodontally healthy subjects for @entity6172 and @entity9492 levels estimation. @entity2521 @entity1 were recalled 3 months postnonsurgical periodontal therapy to re-sample GCF. MATERIALS AND METHODS: @entity6172 and @entity9492 levels were measured by high-performance liquid chromatography. The values were statistically analyzed by Paired t-test. RESULTS: The mean @entity6172 and @entity9492 values in GCF were found to be significantly lower in @entity2521 @entity1 pre- and 3 months post-nonsurgical periodontal therapy, compared with those in the control group subjects. In addition, the successful nonsurgical therapy even though leading to a significant improvement in the @entity6172 and @entity9492 levels, does not restore @entity2041 concentration to the levels seen in healthy subjects. CONCLUSION: Successful nonsurgical periodontal therapy leads to significant improvement in the redox balance ( @entity6172 : @entity9492 ratio) in @entity7278 @entity1 .
