Developmental changes in the expression of enterocytic and hepatic cytochromes P4501A in XXXX .

@entity35 @entity7772 @entity460
1. The development of @entity7772 enzymes was studied in enterocytic and hepatic microsomes from 1-day-old to adult male and female @entity35 . Microsomes were prepared by @entity460 precipitation. Enzyme expression was determined by Western blotting using a polyclonal @entity7772 antibody. 2. The developmental expression of @entity7772 in enterocytic and hepatic microsomes was similar for males and females. 3. Enterocytic @entity7772 ( @entity7772 ) showed a sharp increase at weaning, plateauing at adult levels by 60 days. 4. Hepatic @entity7772 (mostly @entity7772 ) increased sharply just before weaning. However, in contrast to the enterocytic enzyme, there was a 4-fold decrease in enzyme expression down to adult levels by day 60.
