Evaluation of prognostic factors in XXXX .

@entity1 @entity13770 @entity1364 @entity2675 @entity588 @entity5 @entity513 @entity876 @entity1722
We conducted an analysis on 41 cases of @entity2675 (median age 54 y; range 25-82 y) in Kuwait. Most (51%) were @entity5 with 65% arising in the left breast. There were 5 (12%) T1 @entity5 , 23 (56%) T2 @entity5 and 13 (32%) T3/T4 @entity5 . They were mostly (95%) infiltrating @entity513 ; 97% were grade 2 or 3. Axillary lymph node involvement was found in 69%. Estimated 5-year survival rates were 67% and 58% for overall and relapse free survival respectively. Favourable prognosis was associated with age below 50y, clinical stage I and II, small @entity5 size (T1, T2), low @entity5 grade and absence of nodal involvement or distant metastases; nodal status and grade were independent factors for relapse free survival in multivariate analysis. In 18 cases, an immunohistochemical study showed some degree of @entity5 antigen reaction for ER in 89% of cases, PR in 61%, @entity13770 in 44%, CathD in 72%, @entity876 in 56%, @entity1722 in 50%, Ki67 and @entity1364 in 100% and @entity588 in 78%. There were significant associations between several of these factors but none influenced survival. Despite the high incidence of staining of ER, our data do not support the concept of an endocrine pathway that could be usefully antagonized with antioestrogens for therapeutic benefit, as in @entity1 .
