Current radiological techniques used to evaluate unilateral partial ureteral obstruction: an experimental XXXX study.

@entity8 @entity95 @entity3885 @entity4145
AIM: The aim of this study was to evaluate functional and prognostic benefits of Doppler ultrasonography (DU), @entity8 ( @entity8 ), and magnetic resonance urography (MRU) during diagnosis and follow-up of @entity4145 ( @entity4145 ) and to examine apoptosis rates caused by @entity4145 in an experimental @entity95 model. METHOD: Twenty-four @entity95 were divided randomly into two groups. The left kidneys of 15 @entity95 from the first group underwent Ulm-Miller surgery to create @entity4145 , whereas the left kidneys of nine @entity95 from the second group underwent sham surgery. A pressure flow study (Whitaker's test) was done during postoperative week 6. Based on the Whitaker test, the DU, @entity8 , and MRU findings were compared. The number of apoptotic renal cells was counted after death. RESULT: The Whitaker test run during postoperative week 6 revealed @entity3885 in 15 @entity95 from group 1; the nine @entity95 of the sham group had no @entity3885 . Sensitivity and specificity of @entity8 were 93.3 and 88.8 %, respectively, and those of MRU were 93.3 and 88.8 %, respectively. The postoperative mean RI values were significantly higher than the preoperative values, associated with sensitivity of 86.6 % and specificity of 77.5 % for detecting @entity4145 . @entity8 , MRU, and RI could not predict @entity4145 in one (8 %), one (8 %), and two (16 %) kidneys, respectively. Likelihood ratio (LR) was 8.4 for MRU and scintigraphy, while for RI, LR was 3.9. Pathology specimens revealed that all kidneys with @entity4145 underwent apoptosis, and the number of apoptotic cells was significantly higher on the @entity4145 -created side than on the contralateral and in the sham group (p < 0.05). No test predicted all apoptosis related to @entity4145 . CONCLUSION: The RI, @entity8 , and DMRU results correlated with the pressure flow results for detecting @entity4145 . No single radiological technique predicted all initial @entity4145 -created kidneys that concluded with apoptosis. Further studies are required to seek with better methods for diagnosing an obstruction or to define a combination of radiological techniques aiding in the management decision.
