[Compensated @entity3190 based on selective insulin resistance predicts XXXX in non-diabetic adults].

@entity11591 @entity6 @entity13519 @entity3190 @entity13520 @entity551 @entity413
OBJECTIVES: To investigate if @entity3190 or insulin resistance could predict the @entity551 in non-diabetic adults. METHODS: One hundred and seventy non-diabetic adults (NGT 107, IGT 63) were included based on the screen by OGTT in 1986. Height, weight, blood pressure were measured. Plasma @entity413 and insulin concentration at 0.60 and 120 min during OGTT were determined at baseline. All the subjects were followed for six years with blood pressure and plasma @entity413 examined at the end of the study. Subjects worsening to @entity6 were excluded. Insulin area under-curve (INSAUC) and insulin sensitivity index [IAI = (1/FINS x FPG)] were calculated. Stepwise regression analysis was performed to evaluate the effects of INSAUC and insulin sensitivity to the @entity551 . RESULTS: Both @entity13519 and @entity13520 levels at the end of the study were increased with increased INSAUC baseline. The @entity13519 were (119.5 +/- 2.3), (122.1 +/- 2.5), (129.4 +/- 2.4) and (128.3 +/- 2.6) mmHg, and the @entity13520 were (78.6 +/- 1.6), (79.7 +/- 1.7), (85.2 +/- 1.4) and (84.0 +/- 1.0) mmHg from the lowest to the highest quartiles of INSAUC respectively. Pearson correlation analysis showed Age, @entity13519 , @entity13520 , BMI, FINS, INS1h, INSAUC at baseline were positively correlated to blood pressure levels at the end of the study. After the adjustment of Age, sex, BMI, smoking, @entity11591 h and blood pressure at baseline, the INSAUC was significantly correlated to blood pressure six years later, while the insulin sensitivity index was not. CONCLUSION: The compensated @entity3190 based on selective insulin resistance rather than insulin resistance to @entity413 per se could predict the @entity551 in nondiabetic adults.
