@entity16 in experimental and XXXX @entity1315 .

@entity1 @entity410 @entity35 @entity5219 @entity16 @entity3948 @entity1315 @entity302 @entity159 @entity1943 @entity528
The amygdala complex is one component of the temporal lobe that may be damaged unilaterally or bilaterally in @entity1 and adults with @entity1315 ( @entity1315 ) or following @entity159 . Most MR (magnetic resonance) imaging studies of @entity302 @entity1 have shown that volume reduction of the amygdala ranges from 10-30%. In the @entity1 amygdala, @entity528 and @entity5219 have been reported in the lateral and basal nuclei. Studies in @entity35 have more specifically identified the amygdaloid regions that are sensitive to @entity159 -induced @entity528 . These areas include the medial division of the lateral nucleus, the parvicellular division of the basal nucleus, the accessory basal nucleus, the posterior cortical nucleus, and portions of the anterior cortical and medial nuclei. Otherwise, other amygdala nuclei, such as the magnocellular and intermediate divisions of the basal nucleus and the central nucleus, remain relatively well preserved. Amygdala kindling studies in @entity35 have shown that the density of a subpopulation of GABAergic inhibitory neurons that also contain @entity1943 may be reduced even after a low number of generalized @entity410 . While analyses of histological sections and MR images indicate that in approximately 10% of @entity1315 @entity1 , @entity410 -induced damage is isolated to the amygdala, more often amygdala damage is combined with damage to the hippocampus and/or other brain areas. Moreover, recent data from rodents and nonhuman primates suggest that structural and functional alterations caused by @entity410 activity originating in the amygdala are not limited to the amygdala itself, but may also affect other @entity3948 . The information gathered so far on @entity16 in @entity302 or after @entity159 suggests that local alterations in inhibitory circuitries may contribute to a lowered @entity410 threshold and greater excitability within the amygdala. Furthermore, damage to select nuclei in the amygdala may predict impairment of performance in behavioral tasks that depend on the integrity of the amygdaloid circuits.
