Audit of single-stage proctocolectomy for XXXX : @entity260 and recurrence.

@entity1 @entity295 @entity66 @entity29 @entity260 @entity1960 @entity1320 @entity30
PURPOSE: This study was undertaken to review our overall experience of single-stage proctocolectomy for @entity30 . METHODS: One hundred three @entity1 who underwent single-stage proctocolectomy for @entity30 between 1958 and 1997 were reviewed. Factors affecting the incidence of recurrence were examined using a multivariate analysis. RESULTS: Principal indications for proctocolectomy were @entity1960 (49 percent), @entity1960 (37 percent), and @entity66 (14 percent). The commonest postoperative complication was delayed perineal wound healing (n = 36; 35 percent), followed by @entity1320 (17 percent) and stomal complications (15 percent). In 23 @entity1 the perineal wound healed between three and six months after proctocolectomy, whereas in 13 @entity1 the wound remained unhealed for more than six months. There were two hospital deaths (2 percent) caused by @entity295 . The 5-year, 10-year, and 15-year cumulative reoperation rates for small-bowel recurrence were 13, 17, and 25 percent, respectively, after a median follow-up of 18.6 years. From a multivariate analysis, factors affecting reoperation rate for recurrence were gender (male; hazard ratio 2.4 vs. female; P = 0.03) and age at operation (< or =30 years; hazard ratio 2.6 vs. >30 years; P = 0.04). The following factors did not affect the reoperation rate: duration of symptoms, smoking habits, associated perforating disease, coexisting @entity29 , @entity260 , and medical treatment. CONCLUSIONS: Proctocolectomy for @entity30 is associated with a high incidence of complications, particularly delayed perineal wound healing. Proctocolectomy carries a low recurrence rate in the long term. However, young male @entity1 are at high risk of recurrence.
