Ionized serum XXXX levels during @entity810 : @entity400 vs. Continuous hemodiafiltration.

@entity1 @entity3747 @entity2741 @entity400 @entity810 @entity460 @entity1211
BACKGROUND: Achieving "adequacy of dialysis" includes the maintenance of normal serum ionized @entity460 concentrations and is an important therapeutic goal in the treatment of @entity810 ( @entity810 ). It is unknown whether this goal is best achieved with intermittent or continuous renal replacement therapy. METHODS: We compared the effects of @entity1211 ( @entity1211 ) and @entity400 ( @entity400 ) on serum ionized @entity460 concentrations using daily morning blood tests in 88 consecutive intensive care @entity1 of which half were treated with @entity400 and half with CRRT. RESULTS: Mean @entity1 age was 54 +/- 14 years for @entity400 and 60 +/- 14 years for @entity1211 (NS). However, @entity1 who received @entity1211 were significantly more critically ill (mean APACHE II scores: 24.4 +/- 5.1 for @entity400 vs. 29.2 +/- 5.7 for @entity1211 , p < 0.003). Before treatment, the mean ionized @entity460 concentration was 1.177 +/- 0.03 mmol/l for @entity400 and 1.172 +/- 0.04 mmol/l for @entity1211 (NS), with abnormal values in 51.6% of @entity400 @entity1 and in 68% of @entity1211 @entity1 (NS). During treatment, @entity3747 was significantly more common among @entity1211 @entity1 (24.5% vs. 14.9%; p < 0.011) while @entity2741 was more frequent during @entity400 (36.1% vs. 25.6%; p < 0.019). CONCLUSIONS: Abnormal serum ionized @entity460 concentrations are frequent in @entity810 @entity1 before and during renal replacement. Once dialytic therapy is applied, @entity1211 is more likely to lower serum @entity460 concentrations, while @entity400 is more likely to induce @entity2741 . Appreciation of these different biochemical effects may assist clinicians in adjusting dialytic therapy in selected @entity1 .
