Comparative Analysis of @entity460 -Binding Myeloid-Related Protein-8/14 in Saliva and Serum of @entity1 With XXXX and Healthy Individuals.

@entity1 @entity14148 @entity29415 @entity2521 @entity460
BACKGROUND: This study aims to investigate @entity460 -binding myeloid-related protein (MRP)-8/14 in the saliva and serum of individuals with @entity2521 and periodontally healthy individuals for the assessment of its role in the pathogenesis and clinical diagnosis of @entity2521 . METHODS: This cross-sectional study includes 56 @entity1 with @entity2521 and 44 periodontally healthy individuals. Saliva and serum were collected for the detection of @entity29415 /14 and @entity460 levels. Periodontopathic bacteria were determined by polymerase chain reaction in saliva. Correlations between salivary and serum @entity29415 /14 levels and clinical parameters, bacteria, and @entity460 were analyzed with Pearson correlation in a multiple regression model. @entity29415 /14 levels were documented with receiver operating characteristic (ROC) curves. RESULTS: Compared with healthy individuals, @entity29415 /14 levels were significantly higher in both the saliva and serum of @entity1 with @entity2521 , but @entity460 was increased only in saliva. A high diagnostic potential of salivary @entity29415 /14 was detected for @entity2521 (ROC = 0.86). Salivary @entity29415 /14 levels correlated significantly with the presence of the periodontopathogen @entity14148 , as well as with the clinical parameters of @entity2521 . CONCLUSION: @entity29415 /14 in saliva might be a potential diagnostic parameter for periodontal disease.
