[Lobular XXXX of the breast (author's transl)].

@entity1 @entity1137 @entity0 @entity2735 @entity5 @entity189
@entity1137 of the breast, a term which we prefer to that of @entity1137 in @entity2735 , is a multifocal microscopic entity of uncertain and controversial clinical significance. @entity1137 is a incidental histological finding among otherwise benign breast biopsies (0.5%-3.5%) depending mainly upon the diagnostic intensity. Its extent is rarely so massive that it makes up a palpable @entity5 . Although this lesion may be demonstrated at all ages after puberty it occurs most often in premenopausal @entity1 . The multicentricity is not below 70% and bilateral occurrence not below 30-35%. @entity1137 in situ means a 7-12 times greater risk of later developing @entity0 as compared with an age corrected general population. Both breast are at risk and about one half of these @entity189 will develop in the controlateral breast. Attempts at correlating the histological appearances in @entity1137 with the subsequent occurrence of @entity0 have generally be negative. From this data it appears that ipsilateral mastectomy will protect only one half of @entity1 with @entity1137 who will eventually develop @entity189 and the only surgical approach would perform a bilateral mastectomy. As an alternative to mastectomy, a careful program of frequent follow-up examinations, when possible is preferable.
