[Auditory disturbance induced by @entity2049 administration in a @entity1 with secondary generalized XXXX ].

@entity1 @entity135 @entity410 @entity3933 @entity2050 @entity1833 @entity2049
We report on an 18-year-old @entity1 with secondary generalized @entity410 , who developed an auditory disturbance (flat a tone) after @entity2049 ( @entity2050 ) administration. She used to have brief episodes of conjugate deviation of the eyes to the right, @entity135 , teleopsia, and @entity1833 since 16 years of age. At the age of 18 years, she developed a @entity410 during sleep, and was placed on @entity2050 400 mg/day. Immediately after taking the medication, she developed auditory disturbance while she played the musical instruments: she felt as if she played the musical note almost a half tone lower. On admission, neurological examinations and magnetic resonance images of the brain were normal. Electroencephalogram at rest was normal. However, intravenous @entity3933 injection induced spikes in the left temporo-occipital region, followed by diffuse spike and wave complex. Although the serum @entity2050 level was reduced to the therapeutic level by lowering @entity2050 administration from 200 to 150 mg/day, she continued to have the same auditory disturbance. When @entity2050 administration was discontinued, the symptoms also disappeared. It remains unknown whether such a subtle side effect of @entity2050 is a common thing, or it can be recognized only by @entity1 who are well trained in music.
