Intake of @entity1474 and HDL @entity165 levels are associated with manifestations of XXXX in adults.

@entity1 @entity5204 @entity483 @entity66 @entity565 @entity566 @entity1474 @entity402 @entity56 @entity165
BACKGROUND: The increase in @entity56 is still unexplained. It was hypothesized that the intake of @entity1474 is a contributing cause of this development. We investigated the relationship between serum @entity165 levels, intake of @entity1474 ( @entity5204 ) and manifestations of @entity402 in a population-based setting. METHODS: A nested case-control study was performed within the population of the 3rd MONICA survey in Augsburg (Germany). The serum levels of total, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) @entity165 of 1537 adults (aged 28-78 years, response 61.4%) and the estimated intake of @entity5204 in a subset of 139 @entity1 were compared with the frequency of a doctor's diagnosis of @entity565 , @entity56 ( @entity56 ), @entity483 ( @entity483 ) and @entity56 sensitization as measured by skin prick and Radio Allergo Sorbent Test. FINDINGS: In bivariate analyses, we obtained a negative linear association between total and LDL @entity165 levels and the frequency of @entity56 and sensitization, which was no longer significant after adjustment for important confounders. In contrast, positive linear associations were found between HDL @entity165 levels and @entity56 and @entity483 and, furthermore, between the intake of @entity5204 and @entity56 sensitization in @entity1 (P<0.01). After adjustment, an increasing risk for @entity66 with increasing levels of HDL @entity165 and an increasing risk for @entity56 sensitization with increasing intakes of @entity5204 remained statistically significant. INTERPRETATION: There is indication that HDL @entity165 also plays a role in the complex interaction of fat intake, metabolism and the manifestation of @entity402 in adults. These findings may contribute to the understanding of time trends and regional differences of @entity566 .
