XXXX in Brazil.

@entity1 @entity66 @entity231 @entity1596 @entity726 @entity7375 @entity230
A retrospective analysis of 33 @entity1 with @entity7375 ( @entity7375 ) seen in S  o Paulo, Brazil, from 1976 to 1985 at a @entity1596 referral clinic revealed that @entity7375 represents 2.5% of the total @entity1596 cases seen. All cases were bilateral, 30% being @entity1 and 70% @entity1 . The ethnic distribution was the following: 60% white (with variable Indian or black extraction), 24% darkly pigmented, 9% Orientals (Sansei, third-generation Japanese) and 6% black. The frequency among Orientals was 7 times higher than what would be expected according to the relative frequency of Japanese in the Brazilian population. The age distribution at the onset of the disease was as follows: 12% less than 20 years of age, 60% between 20 and 40 years of age and 27% over 40 years of age. The disease was classified into 3 types with variable extraocular signs. @entity66 was present in 24% of the @entity1 , type II in 51% and @entity66 in 24% of the @entity1 . @entity231 was present in 40% of the cases and @entity726 was present in 9%. No correlation was found between sex, age at onset, race, type of extraocular involvement and number of extraocular manifestations in considering either visual status or visual prognosis. All @entity1 were treated with systemic @entity230 . Most of them also received cytotoxic immunosuppressive agents. In this uncontrolled clinical study cytotoxic drug-treated @entity1 seemed to have a better clinical course.
