Wide-Field Fundus Autofluorescence Imaging to Evaluate Retinal Function in @entity1 With XXXX .

@entity1 @entity227 @entity6391 @entity989 @entity1019
PURPOSE: To study the correlation between the @entity227 ( @entity227 ) and wide-field fundus autofluorescence (FAF) in @entity1 with @entity6391 ( @entity6391 ). DESIGN: Retrospective, observational, consecutive case series. METHODS: Twenty-four eyes of 12 @entity1 diagnosed with @entity6391 were enrolled. The VFs measured by Goldmann perimetry and wide-field FAF images were compared for each eye. The relationship between the areas of hypoautofluorescence on the wide-field FAF images and @entity1019 on Goldmann perimetry were evaluated. The @entity227 and FAF images in the central 60 degrees were trimmed and superimposed to calculate the percentage agreement between the hypoautofluorescence and the @entity1019 and between the isoautofluorescence and hyperautofluorescence and the remaining VFs. RESULTS: The areas of hypoautofluorescence on the FAF images were correlated significantly (R  = 0.86, P < .001) with the areas of the @entity227 on Goldmann perimetry. The mean percentage agreement between the hypoautofluorescence and the @entity1019 was 91.0%    7.7% and that of the isoautofluorescence and hyperautofluorescence with the remaining VFs was 84.5%    7.4%. The areas of geographic hypoautofluorescence with or without hyperautofluorescent bands reflected the @entity227 , while nummular or mottled hypoautofluorescence without @entity227 was seen in 7 eyes. CONCLUSIONS: These results suggested that wide-field FAF imaging is useful to evaluate the remaining retinal function in @entity1 with @entity6391 . Abnormal fundus autofluorescence precedes @entity989 and is helpful for monitoring disease progression.
