Role of Transjugular Intrahepatic Portosystemic Shunts in the XXXX : A Systemic Literature Review.

@entity1 @entity295 @entity7185 @entity881
PURPOSE: To evaluate the role of transjugular intrahepatic portosystemic shunt (TIPS) creation in the management of @entity7185 ( @entity7185 ). MATERIALS AND METHODS: A MEDLINE (PubMed) search from January 1990 to April 2015 was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search was restricted to the English language and @entity1 subjects. Inclusion criteria were @entity1 with @entity7185 who underwent TIPS creation for any indication. Exclusion criteria was age < 18 years. RESULTS: Ten studies consisting of 12 @entity1 with @entity7185 were included. Eight @entity1 had very severe @entity7185 , 2 had severe @entity7185 , and 2 had moderate @entity7185 . Transjugular intrahepatic portosystemic shunt creation was technically successful in all @entity1 , without complications. Mean portosystemic pressure gradients before and after the procedure were 18.2 mm Hg (range, 10-30 mm Hg) and 6.5 mm Hg (range, 3-15 mm Hg), respectively. The mean duration of follow-up was 9.3 months (range, 0.75-36 mo). Improvement in oxygenation occurred in 9 @entity1 but was not sustained after 4 months in 2 @entity1 . In the remaining 3 @entity1 , oxygenation remained unchanged; it worsened after 4 months in 1 @entity1 . Four @entity1 underwent liver transplantation. Two @entity1 died of multiple @entity881 and 1 died of @entity295 . The remaining @entity1 were alive and well at the time of last follow-up. CONCLUSIONS: Transjugular intrahepatic portosystemic shunt creation shows promise in the management of @entity7185 . Future prospective studies are warranted.
