A specific role of endoscopic ultrasonography for therapeutic decision-making in @entity1 with XXXX .

@entity1 @entity5 @entity4617 @entity418 @entity356
BACKGROUND: The role of endoscopic ultrasonography (EUS) in @entity356 should be further evaluated because the accuracy of EUS depends on @entity5 location. We aimed to identify a specific role of EUS for therapeutic decision-making in @entity1 with @entity356 . METHODS: Initial EUS examinations for treatment-na  ve @entity356 that were followed by endoscopic resection or surgery were included in the study. Lesions were classified as @entity4617 according to @entity5 location. The diagnostic performance of EUS in predicting invasion depth was compared between the two groups. RESULTS: The overall accuracy of EUS in predicting invasion depth did not differ between the @entity4617 groups (44.4 vs. 52.3  %, P  =  0.259). The underestimation rate was higher in the @entity4617 group than in the @entity4617 group (37.0 vs. 18.5  %, P  =  0.001). When the depth of invasion was predicted to be deeper than the mucosa (submucosal or deeper) by EUS, the positive predictive value was 82.1 [95  % confidence interval (CI), 66.5-92.5  %] and 62.9  % (95  % CI, 60.5-66.9  %) in the @entity4617 groups, respectively (P  =  0.015). In multivariable analysis, @entity5 location in the @entity418 was found to be an independent factor for the underestimation of invasion depth [odds ratio (95  % CI)  =  2.242 (1.156-4.349)]. CONCLUSIONS: The underestimation rate in predicting invasion depth was significantly higher for @entity4617 . Therefore, selection of the treatment method for @entity356 via EUS should be done carefully.
