Examination of the validity of the Brief Neurocognitive Assessment (BNA) for XXXX .

@entity1 @entity73 @entity149 @entity161
BACKGROUND: Although many comprehensive batteries exist to evaluate the nature and degree of @entity73 in @entity1 with @entity161 , short batteries hold promise for rapidly screening and estimating @entity73 . Recently, the Brief Neurocognitive Assessment (BNA) was established and has been shown to have similar validity and utility to a more comprehensive battery of cognitive tests in evaluating global @entity73 in @entity1 with @entity161 . The present study sought to further establish the validity of the BNA by comparing it with the MATRICS Consensus Cognitive Battery (MCCB). METHODS: One-hundred seventy-six @entity1 with @entity161 and 300 healthy volunteers participated in the present study. Global cognition was evaluated using the MCCB composite score and estimated using the BNA. To examine practice effects and test-retest reliability, @entity1 were re-assessed after 4weeks. RESULTS: The BNA was highly correlated with global cognition as evaluated by the MCCB in both the @entity161 (r=0.82) and healthy control samples (r=0.75). Both instruments were similarly sensitive to @entity73 in @entity1 with @entity161 relative to healthy controls. The BNA also demonstrated high test-retest reliability in @entity1 with @entity161 (r=0.87), comparable to the level observed with the MCCB (r=0.91). In addition, both the BNA and MCCB showed a similar level of practice effects (both Cohen's d=0.11), and both instruments demonstrated equivalent sensitivities to longitudinal change. Furthermore, scores from the BNA and MCCB were related to symptom severity and functional capacity to a similar degree. CONCLUSIONS: The BNA provides clinicians and researchers with an efficient and reliable means by which to evaluate global @entity149 in @entity1 with @entity161 by allowing estimation of performance on a more comprehensive standardized battery.
