Age and the burden of @entity204 attributable to XXXX in the United States.

@entity1 @entity204 @entity65 @entity6
@entity6 is a well-established cause of @entity65 ( @entity65 ) and all-cause mortality. The burden of @entity204 attributable to @entity6 in the United States is not well quantified, particularly with regard to age. The authors analyzed data from the Second National Health and Nutrition Examination Survey (NHANES II) (1976-1980) and the NHANES II Mortality Study, in which a nationally representative cohort of 9,250 adults aged 30-75 years was followed for 12-16 years, to determine all-cause and cause-specific mortality. Overall, between 1976 and 1980, the prevalence of diagnosed @entity6 was 4.3%. By 1992, the relative hazard of all-cause mortality was 1.9 (95% confidence interval: 1.5, 2.3), and the population attributable risk (PAR) was 3.6%. The relative hazard of @entity65 mortality was 2.3 (95% confidence interval: 1.8, 2.8), and the PAR was 5.2%. Including @entity1 with undiagnosed @entity6 in the estimates increased the PAR for all-cause mortality to 5.1% and that for @entity65 mortality to 6.8%. @entity1 had a higher prevalence of diagnosed @entity6 than @entity1 and a greater relative hazard of @entity204 than nondiabetic @entity1 , leading to a higher PAR for @entity1 (3.8% for all causes and 7.3% for @entity65 ) versus @entity1 (3.3% for all causes and 3.8% for @entity65 ). These data suggest that @entity6 accounts for at least 3.6% of all @entity204 and 5.2% of @entity65 @entity204 in US adults. Improvements in @entity6 prevention and treatment should produce noticeable effects on US life expectancy.
