The association between epicardial fat thickness and XXXX according to blood pressure status in nonhypertensive individuals: From the CAESAR study.

@entity1 @entity460 @entity729 @entity453 @entity1556
BACKGROUND: Epicardial adipose tissue represents visceral adiposity, and the coronary artery @entity460 (CAC) score (CACS) has been suggested as a reasonable surrogate for @entity453 . Epicardial fat thickness (EFT) and blood pressure status can be attributed to @entity729 . OBJECTIVE: The present study was performed to evaluate the association between EFT and @entity729 according to blood pressure status in nonhypertensive individuals. METHODS: The CACS and echocardiographic EFT measurement were performed in a total of 1878 nonhypertensive individuals (1535 @entity1 ; mean age, 44      8.3  years). Subjects were divided into quartiles according to EFT ( <=2.575, 2.576-3.168, 3.169-3.900, and >3.900  mm) and into 2 groups according to the presence of CAC. Additionally, individuals were classified as normotensive (n  =  1064) or @entity1556 (n  =  814). RESULTS: The prevalence of CACS >0 group in @entity1556 individuals was 6.1%, 18.1%, 22.6%, and 29.9% in the lowest, second, third, and highest EFT quartiles, respectively (P  <  .001) and 7.3%, 13.1%, 14.0%, and 13.9% in the normotensive group (P  =  .050). On multivariate regression analysis, the second, third, and highest quartile EFT groups had higher odds ratios for the presence of CAC than that of the lowest quartile (odds ratio [95% confidence interval], 3.849 [1.215-12.194], 4.069 [1.235-13.412], and 4.383 [1.385-13.875], respectively), although only in @entity1556 individuals. Moreover, an increased absolute EFT level was also associated with increased CACS in @entity1556 individuals (standardized b  =  0.101, P  =  .035). CONCLUSION: This study showed an independent relationship between EFT and @entity729 in nonhypertensive individuals, with variable differences in this association according to blood pressure status.
