Can T2 relaxation values and color maps be used to detect XXXX utilizing subchondral @entity236 as a marker?

@entity1 @entity236 @entity16
OBJECTIVE: This study aimed to investigate whether a commercially available time-efficient T2 mapping sequence will demonstrate findings of articular cartilage degeneration based on T2 relaxation values (RV) and color maps, using subchondral @entity236 ( @entity236 ) as a marker for @entity16 . MATERIALS AND METHODS: The @entity1 group consisted of 88 subjects who underwent knee magnetic resonance imaging at 1.5 T who had subchondral @entity236 evident on fat-suppressed T2-weighted sequences. The control group was comprised of 60 subjects with no evidence of subchondral @entity236 . A commercially available eight echo T2 relaxation sequence (acquisition time 8:36 min) was used to construct a T2 color map and to determine T2 RVs. T2 RVs were determined on cartilage overlying subchondral @entity236 in @entity1 and in eight pre-determined anatomical regions in controls. T2 color maps in the @entity1 and control groups were analyzed for degree of color stratification (presence = two or more colors) at the same anatomic site as that used for T2 RV determination. RESULTS: T2 RVs were significantly increased in @entity1 compared to controls for the medial femoral condyle (MF; p < 0.01), medial patellar facet (MP; p < 0.01), lateral patellar facet (LP; p < 0.01), lateral femoral condyle (LF; p < 0.01) and lateral tibial plateau (LT; p < 0.01). Loss of color stratification was noted in @entity1 compared to controls in the medial tibial plateau (MT; p = 0.01), LF (p < 0.01), and LT (p < 0.01). In the @entity1 group, increase in T2 RVs was associated with corresponding decrease in color stratification in MF (p < 0.01), MT (p < 0.01), MP (p < 0.01), medial femoral trochlear groove (p = 0.02), and lateral femoral trochlear groove (p < 0.01). CONCLUSION: Subchondral @entity236 was associated with an increase in adjacent articular cartilage T2 RVs at some sites. Also, elevated T2 RVs were associated with loss of color stratification.
