Continuous epidural infusion of 0.0625% @entity1341 -0.0002% XXXX during the second stage of labor.

@entity1 @entity1341 @entity3575 @entity158
A randomized, double-blind, placebo-controlled study was performed to evaluate the analgesic efficacy and influence of continuing an epidural infusion of 0.0625% @entity1341 -0.0002% @entity3575 during the second stage of labor in nulliparous @entity1 . When the cervix was fully dilated, coded study solution was substituted for the known @entity1341 - @entity3575 solution. The study solution for 29 @entity1 was 0.0625% @entity1341 -0.0002% @entity3575 ; 34 @entity1 received saline placebo. The two groups had similar @entity158 scores during the first stage of labor. During the second stage, @entity158 scores were significantly higher in the saline-placebo group at each 30-min interval between 60 and 150 min after the diagnosis of full cervical dilation. Similarly, there was a significant difference between the two groups in global assessment of analgesia quality during the second stage, but the difference occurred in those @entity1 with a second-stage duration of greater than or equal to 60 min. Among the @entity1 who delivered vaginally, eleven of 28 (39%) @entity1 in the @entity1341 - @entity3575 group, versus five of 34 (15%) in the saline-placebo group, had surgical perineal anesthesia for vaginal delivery (P less than .05). Six of 28 (21%) @entity1 in the @entity1341 - @entity3575 group, and five of 34 (15%) in the saline-placebo group, underwent instrumental vaginal delivery (P = NS). The median duration of the second stage of labor was 53 min (range = 5-283) in the @entity1341 - @entity3575 group, and 63 min (range = 16-181) in the saline-placebo group (P = NS).(ABSTRACT TRUNCATED AT 250 WORDS)
