Heme oxygenase levels and metaflammation in XXXX @entity1 .

@entity1 @entity32 @entity1069 @entity6 @entity1067 @entity1674 @entity36702 @entity13975 @entity209 @entity1446
PURPOSE: To investigate the relationship between intra-prostatic levels of @entity1446 oxygenase (HO), metaflammation in @entity1067 ( @entity1067 ) tissue in @entity1 with @entity209 and moderate-severe lower urinary tract symptoms (LUTS). METHODS: Between January 2012 and June 2013, 132 consecutive @entity1 , who underwent transurethral resection of the prostate for moderate-severe LUTS, secondary to clinical @entity1067 , were enrolled. Prostate samples were investigated for the presence of an inflammatory infiltrate, according to the Irani score, and for @entity13975 and @entity36702 levels measurements. @entity1 were evaluated for the presence of @entity209 ( @entity209 ) defined by the International @entity6 Federation. RESULTS: We observed that subjects with @entity209 exhibited greater Irani score (3.0 vs. 2.0; p  <  0.05), Irani grade (2.0 vs. 1.0; p  <  0.05) and lower value of @entity13975 (4.55 vs. 6.01; p  <  0.05) and @entity36702 (0.81 vs. 2.66; p  <  0.05). @entity13975 (3.91 vs. 5.67; p  <  0.05) and @entity36702 (1.06 vs. 1.37; p  <  0.05) were significantly reduced in @entity1 with @entity1069 (Irani score  >= 4). At the multivariate logistic regression analysis, @entity13975 reduction (OR 0.588; p  <  0.01), waist circumference (OR 1.09; p  <  0.01), @entity1674 (OR 1.013; p  <  0.05) and HDL (OR 0.750; p  <  0.05) were independent predictors of @entity1069 . We also found that @entity13975 reduction (OR 0.598; p  <  0.01) and the presence of @entity209 (OR 34.846; p  <  0.01) were associated with Irani score  >= 4. CONCLUSION: @entity209 -induced @entity32 may play a key role in @entity1067 . In detail, prostate metaflammation is inversely related to intra-prostatic @entity13975 levels, serum HDL and positively with @entity1674 .
