Comparison of endoscopic stenting for XXXX : A single-center study.

@entity1 @entity3883 @entity788 @entity66 @entity5 @entity1702
AIM: To evaluate the efficacy and safety of single-step endoscopic placement of @entity1702 ( @entity1702 ) for treatment of @entity3883 . METHODS: A retrospective study was performed among 90 @entity1 who underwent transpapillary biliary metallic stent placement for @entity5 ( @entity5 ) between April 2005 and October 2012. The diagnosis of @entity66 and @entity5 was based on abdominal ultrasound, computed tomography, magnetic resonance imaging, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography with brush cytology, biopsy, and/or a combination of these modalities. The type of @entity1702 (covered or non-covered, 8 mm or 10 mm in diameter) was determined by the endoscopist. Ninety @entity1 were divided into two groups: group 1 (49 @entity1 ) who underwent a single-step @entity1702 placement and group 2 (41 @entity1 ) who underwent a two-step @entity1702 placement. The technical success rate, complication rate, stent patency, and @entity1 survival rate were compared between the groups. In addition, to identify the clinical prognostic factors associated with @entity1 survival, the following variables were evaluated in Cox-regression analysis: gender, age, etiology of @entity5 ( @entity788 ), clinical stage (IVb; with distant metastases or IVa >; without distant metastases), chemotherapy (with or without), patency of the stent, and the use of single-step or two-step @entity1702 . RESULTS: Immediate technical success was achieved in 93.9% (46/49) in group 1 and in 95.1% (39/41) in group 2, with no significant difference (P = 1.0). Similarly, there was no difference in the complication rates between the groups (group 1, 4.1% and group 2, 4.9%; P = 0.62). Stent failure was observed in 10 cases in group 1 (20.4%) and in 16 cases in group 2 (39.0%). The patency of stent and @entity1 survival revealed no difference between the two groups with Kaplan-Meier analysis, with a mean patency of 111    17 d in group 1 and 137    19 d in group 2 (P = 0.91), and a mean survival of 178    35 d in group 1 and 222    23 d in group 2 (P = 0.57). On the contrary, the number of days of hospitalization associated with first-time @entity1702 placement in group 1 was shorter when compared with that number in group 2 (28 vs 39 d; P < 0.05). Multivariate analysis revealed that a clinical stage of IVa > (P = 0.0055), chemotherapy (P = 0.0048), and no patency of the stent (P = 0.011) were independent prognostic factors associated with @entity1 survival. CONCLUSION: Our results showed that single-step endoscopic metal stent placement was safe and effective for treating @entity3883 secondary to various inoperable @entity5 .
