Longterm follow-up of childhood XXXX with absences. I. @entity302 with absences at onset.

@entity1 @entity410 @entity109 @entity302 @entity2048 @entity17979
The purpose of the follow-up study was to determine whether modern therapy with @entity17979 and/or valproate with/without @entity109 and its derivatives improves the longterm prognosis of @entity2048 as compared to formerly used treatments. The @entity1 population consisted of 194 cases (88 @entity1 , 106 @entity1 ) with spike wave @entity302 starting with absences. In each case the diagnosis was confirmed by clinical observation and the typical EEG pattern. Only those @entity1 were included who could be followed beyond the eighteenth year of life (up to age 45). The sample includes also older @entity1 diagnosed during the fifties, before the present standard therapy was available. Because of the heterogeneity of the material and its selection, the data obtained are not suited to make a general statement about the ultimate prognosis of absences. The results demonstrate the effectiveness of regularly applied modern treatment. 72 out of 194 @entity1 (37%) manifested generalized @entity410 (gtcs) during the course: 20 of these @entity1 showed only incidental generalized @entity410 , which were not dependent on therapy. In 52 cases gtcs appeared without relation to precipitating factors. None of these @entity1 received regular standard therapy before onset of gtcs. In 31 cases absence statuses were observed. These @entity1 did not have an unfavourable outcome provided the standard therapy was instituted early and consequently. A change from @entity2048 into an @entity302 with complex partial @entity410 sensu strictiori could not be observed. At final investigation 42 of 194 @entity1 still had @entity410 : 7 with absences, 35 with grand mal with or without absences.(ABSTRACT TRUNCATED AT 250 WORDS)
