Prenatal role of the ductus arteriosus in XXXX .

@entity1 @entity1145 @entity409 @entity1757 @entity245 @entity338 @entity1001
@entity338 with @entity1757 is associated with ductal agenesis and markedly dilated main and branch pulmonary arteries. The less common variant with intact ventricular septum generally exhibits a patent ductus and smaller branch pulmonary arteries, and may be associated with @entity1145 . We identified 7 @entity1 with the prenatal diagnosis of @entity338 , 5 with @entity1757 (Group 1) and 2 with an intact ventricular septum (Group 2). Imaging, color Doppler, and pulsed-Doppler recordings were analyzed. The branch and main pulmonary arteries were measured and expressed as a ratio with the descending aorta. @entity338 time (PRT) and diastolic acceleration time (DAT) were derived, and DAT/PRT was calculated to characterize diastolic pulmonary flow. Group 1 @entity1 all had a large @entity1757 , normal biventricular size and function, and dilated main and branch pulmonary arteries. Group 2 @entity1 had dilated main but smaller branch pulmonary arteries, moderate @entity1001 with severe @entity409 , and limited or absent tricuspid inflow. Group 1 demonstrated shorter acceleration time and earlier peak velocity, resulting in a smaller DAT/RT ratio. We speculate that free communication between the fetal aorta and the ventricles may limit atrial inflow and elevate diastolic pressure, affecting cardiac output, ventricular function, and @entity245 . With an intact ventricular septum, these physiologic and anatomic repercussions are limited to the right ventricle, but with a @entity1757 , both ventricles would experience similar consequences and cardiac performance could be critically impaired.
