The Impact of Visual Field Clusters on Performance-Based Measures and Vision-Related Quality of Life in @entity1 with XXXX .

@entity1 @entity2194 @entity227 @entity726 @entity735
PURPOSE: To investigate how @entity227 ( @entity227 ) clusters affect performance-based measures of the ability to perform activities of daily living and subjective measures of vision-related quality of life (QoL) in @entity1 with @entity726 . DESIGN: Prospective, cross-sectional study. METHODS: Setting: Institutional - Wills Eye Hospital. STUDY POPULATION: 322 eyes of 161 @entity1 with moderate-stage @entity726 . OBSERVATION: @entity227 tests were conducted using the Humphrey 24-2 Swedish interactive thresholding algorithm standard perimeter. The VFs of each @entity1 were divided into five clusters: nasal, temporal, central, paracentral and peripheral. The score for each cluster was the averaged total deviation scores of all tested points within the cluster. Each cluster score was correlated with performance-based measures of visual function and subjective assessment of vision-related QoL. MAIN OUTCOME MEASURES: The Compressed Assessment of Ability Related to Vision, the National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25) and the Modified @entity726 Symptom Scale. RESULTS: The central @entity227 cluster in the better eye was positively correlated with all Compressed Assessment of Ability Related to Vision (performance-based measure) subscales. The strongest correlation for the better eye was between the central @entity227 cluster and total Compressed Assessment of Ability Related to Vision score (0.39, P< 0.001). The inferior @entity227 hemisphere in both eyes was positively correlated with most Compressed Assessment of Ability Related to Vision subscales. Central @entity227 in the better eye were positively correlated with a majority of the NEI VFQ-25 subscales. There were no significant correlations between @entity227 and Modified @entity726 Symptom Scale subscales. CONCLUSIONS: Scores of central @entity2194 in both eyes were positively correlated with performance-based measures of the ability to perform activities of daily living. @entity726 @entity1 with central @entity735 were more likely to have reduced scores on assessments of vision-related QoL.
