XXXX of the eyelids.

@entity1 @entity6461 @entity957 @entity5
AIM: To review the clinical features, management, and outcomes of surgical treatment of @entity957 ( @entity6461 ). METHODS: A retrospective review of all eyelid SCCs treated between 1992 and 2001. RESULTS: 51 cases were identified in 50 @entity1 . @entity1 ages ranged from 26 to 93 years, with a mean age of 65 years. 33 @entity1 were male and 17 were female. The lesion was found on the lower lid in 31 cases, upper lid in five cases, lateral canthus in six cases, and medial canthus in nine cases. Perineural invasion was found in four @entity1 , and orbital invasion in three @entity1 . Recurrence occurred in one @entity1 . Treatment was by complete excision with histological confirmation of clear margins. Exenteration was required in three @entity1 . No @entity1 developed lymph node or distant metastases. One @entity1 , who declined treatment, died as a result of the @entity5 . Mean follow up was 31.1 months. CONCLUSIONS: Eyelid @entity6461 is a relatively uncommon, but potentially fatal disease. However, if detected early and treated adequately, the prognosis is generally excellent. Treatment by complete excision with histological confirmation of @entity5 clearance is recommended. Perineural spread is an adverse prognostic sign, which may require postoperative radiotherapy. Orbital invasion is a rare complication but, if recognised early, can be treated effectively with exenteration. Because presentation varies and histological examination is required for accurate diagnosis, any suspicious lesion occurring on the eyelids should be excised or biopsied. All @entity1 with eyelid @entity6461 should be advised of the risk of recurrent or new @entity5 and encouraged to attend lifelong follow up. Prevention remains of prime importance in minimising the morbidity and mortality of these lesions.
