The relationship between a low treated blood pressure and IHD mortality: a report from the DHSS XXXX Care Computing Project (DHCCP).

@entity1 @entity11559 @entity101 @entity299
The suggestion that treating blood pressure to below a certain level may increase IHD mortality is controversial. We investigated the influence of treated blood pressure on mortality in the DHSS @entity101 Care Computer Project. Mortality was examined by quintiles of treated diastolic blood pressure (DBP) in 2,145 @entity1 treated for a minimum period of one year and subsequently followed for an average of four years. One hundred and seventy five @entity1 died; 71 from IHD. In @entity1 and @entity1 all cause mortality increased with level of treated DBP. In @entity1 IHD mortality showed a U-shaped distribution with an age-adjusted rate of 15.2 per 1,000 @entity1 years in the lowest fifth (DBP less than 86 mmHg) comparable to that of 15.6 per 1,000 in the upper (DBP greater than or equal to 103 mmHg). A similar pattern could not be established in @entity1 due to very few IHD deaths. IHD mortality was further examined separately for @entity1 by prior history of IHD. An increase in IHD deaths in the lowest fifth of treated blood pressure was found for @entity1 both with and without a history of IHD. No similar pattern of IHD mortality was obtained for untreated @entity11559 or treated systolic pressure. However, we cannot exclude the possibility that the risk of low treated DBP is secondary to @entity299 .
