@entity5 with XXXX like clear cells: Experience from a tertiary care hospital in Pakistan.

@entity1 @entity548 @entity39 @entity5 @entity75 @entity10 @entity3271
BACKGROUND: @entity5 with @entity3271 like clear cells have never been reported from Pakistan. We aimed to see the features and outcomes of this rare entity. METHODS: It was retrospective cohort conducted at the Department of Neurosurgery, Aga Khan University from 2003 to 2013. The medical records and radiology of @entity1 with proven histopathology were reviewed. Analysis was done on SPSS 20. RESULTS: Eleven cases of @entity5 with clear cells were found, which equated to 1.5% of the total @entity5 burden in 11 years. The median age was 49 years. Most common presenting symptom was @entity10 54.5%. Out of 11 @entity1 , 9 @entity1 had a @entity5 . Magnetic resonance imaging showed hypointense signals on T1 and hyperintense signals on T2-weighted images in all cases. Contrast enhancement was found in 9 @entity1 (77.8%), @entity39 and @entity548 was found in 4 (36%) and 3 (27%) @entity1 , respectively. Immunohistochemistry showed glial fibrillary acidic protein and epithelial membrane antigen positivity in all cases. Ki-67 showed high proliferative index in 6 @entity1 . According to the World Health Organization grading of @entity5 , 2 @entity1 had @entity5 , and 9 @entity1 had @entity5 with clear cells. Gross total resection was achieved in 6 (54.5%) and subtotal resection in 5 @entity1 (45.4%). Recurrence was observed in 9 @entity1 . Six @entity1 died of the disease. Median progression-free survival and overall survival was 8 months and 10 months, respectively. CONCLUSION: @entity5 with clear cells presented more commonly in @entity75 and were more aggressive in behavior with poorer outcome compared to similar studies.
