Prevalence of XXXX biotypes and their clinical significance in a University Hospital.

@entity1 @entity2261 @entity2756 @entity799 @entity327 @entity2177 @entity281 @entity3 @entity1215 @entity869 @entity2755
OBJECTIVE: Hemophilus influenzae is an important pathogen that is responsible for invasive and @entity3 in both @entity1 and adults. This study aims to assess the relationship of biotypes to the sites of @entity281 , serotypes, antimicrobial susceptibility, beta-lactamase production and age. METHODS: A total of 200 isolates of @entity327 were obtained from clinical specimens over a period of 12 months from January 2001 through to January 2002 from King Abdul-Aziz University Hospital, Riyadh, Kingdom of Saudi Arabia. RESULTS: Most of the strains were non-typable and were isolated from @entity1 with @entity3 . The typable isolates from invasive @entity281 mostly serotype b were isolated from blood, cerebrospinal fluid and hip joint aspirate. Biotype II accounted for 37% of the isolates followed by biotypes III and I (29.5% and 23%). The remaining 10.5% were made up of biotypes IV, V, VI and VII. A significantly high resistance to @entity799 (33.5%) and @entity869 (19%) was observed. Two point five percent of the isolates were resistant to @entity2755 . All the isolates resistant to @entity869 were beta-lactamase producers and susceptible to @entity2261 , @entity2756 , @entity2177 and @entity1215 . CONCLUSION: This study revealed that biotypes II and III are the predominant biotypes of @entity327 found in @entity3 . There is an apparent relationship between biotype and site of @entity281 which could be useful as an epidemiological marker.
