Gender difference in prognostic impact of in-hospital @entity548 after XXXX - data from the SWEDEHEART registry.

@entity1 @entity583 @entity36386 @entity548
BACKGROUND: Bleeding complications increase mortality in @entity583 @entity1 . Potential gender difference in @entity548 regarding prevalence and prognostic impact is still controversial. OBJECTIVES: Gender comparison regarding incidence and prognostic impact of @entity548 in @entity1 hospitalised with @entity583 during 2006-2008. METHODS: Observational study from the SWEDEHEART register. Outcomes were in-hospital bleedings, in-hospital mortality and one-year mortality in hospital survivors. RESULTS: A total number of 50,399 @entity583 @entity1 were included, 36.6% @entity1 . In-hospital bleedings were more common in @entity1 (1.9% vs. 3.1%, p<0.001) even after multivariable adjustment ( @entity36386 , 95% confidence interval (CI) 1.01-1.37). The increased risk for @entity1 was found in ST-elevation @entity583 (OR 1.46, 95% CI 1.10-1.94) and in those who underwent percutaneous coronary intervention (OR 1.80, 95% CI 1.45-2.24). In contrast the risk was lower in medically treated @entity1 (OR 0.79, 95% CI 0.62-1.00). After adjustment, in-hospital @entity548 was associated with higher risk of one-year mortality in @entity1 (OR 1.35, 95% CI 1.04-1.74), whereas this was not the case in @entity1 (OR 0.97, 95% CI 0.72-1.31). CONCLUSIONS: Female gender is an independent risk factor of in-hospital @entity548 after @entity583 . A higher @entity548 risk in @entity1 appeared to be restricted to invasively treated @entity1 and ST-elevation @entity583 @entity1 . Even though @entity1 have higher short- and long-term mortality, there was no difference between the genders among bleeders. After multivariable adjustment the prognostic impact of @entity548 complications was higher in @entity1 .
