Corneal Densitometry, Central Corneal Thickness, and Corneal Central-to-Peripheral Thickness Ratio in XXXX With Fuchs Endothelial Dystrophy.

@entity1 @entity2840 @entity2687 @entity33295 @entity13189
PURPOSE: The aim of the study was to quantify Scheimpflug corneal densitometry in @entity1 with @entity13189 ( @entity13189 ). METHODS: In this study, we retrospectively reviewed the charts and anterior segment data of 49 @entity1 with @entity13189 before posterior lamellar keratoplasty and 51 healthy controls. The @entity1 were examined using the Scheimpflug-based Oculus Pentacam. @entity2840 ( @entity2840 ), ring-averaged (on a circle of 2, 2.4-10 mm diameter) noncentral @entity2687 , and densitometry data in different corneal layers and in different annuli were extracted and analyzed. RESULTS: The total corneal light backscatter at total @entity2687 ( @entity2687 ) and at total diameter was significantly higher in the @entity13189 group when compared with the control group ( @entity13189 group: 28.8    6.7; control group: 24.3    4.1; P < 0.001). When the corneal surface was divided into concentric annular zones at total @entity2687 , the differences were significant only in the 2 central annuli (P < 0.001). The total corneal light backscatter at total @entity2687 in the central 0-2 mm annulus correlated moderately with the central @entity2687 (Pearson's correlation = 0.55, P < 0.001). CONCLUSIONS: Corneal light backscatter in the central cornea was greater in @entity1 with @entity13189 than in normal subjects. Corneal densitometry enables us to evaluate the optical quality of the @entity33295 and in different annuli. It is a useful, objective method that, in combination with central @entity2687 and corneal central-to-peripheral thickness ratio, can help to quantify @entity13189 severity.
