[Cervix ripening using drugs before XXXX labor induction. Clinical study of a new @entity1421 triacetin gel].

@entity398 @entity1421 @entity1 @entity56009
In an open randomized clinical study, 50 of 100 gravidae with a low Bishop score (less than or equal to 5) at term were treated with @entity1421 (0.5 mg @entity1421 in 2.5 ml Triacetin gel. @entity56009 , intracervically) 12 hours before the indicated i.v. @entity398 induction. In 50 @entity1 labor was induced intravenously without any pretreatment. In 46 of 50 pretreated @entity1 (92%) there was an increase in the Bishop score of at least three points, and of only two points in the remaining four. In the control group no significant increase in the Bishop score was measurable. Sixteen @entity1 delivered within the first 12 hours after @entity1421 gel administration, before @entity398 induction. Three @entity1 in the untreated control group also delivered during this pre-observation period. In 14 (64%) of 22 @entity1 in whom cervical priming with @entity1421 was performed and 26 (57%) of 47 @entity1 in whom it was not the first intravenous @entity398 induction was successful. The frequency of cesarean sections was 10% (n = 5) in the @entity1421 gel group and 12% (n = 6) in the @entity398 group. The @entity398 dose needed to induce labor was significantly lower after cervical priming. No severe side effects were observed during and after @entity1421 treatment, in either the mothers or the @entity1 .
