Clinical characteristics and advantages of primary peripheral micro-sized XXXX over small-sized @entity2220 .

@entity1 @entity5 @entity787 @entity420 @entity3 @entity15709 @entity2220
OBJECTIVES: Micro-sized @entity2220 with a @entity5 of 1.0 cm or less could help identify the @entity1 who would undergo the surgery treatment with limited resection; however, its clinical characteristics and survival rates remain unclear and are to be tested further. METHODS: Histology, lymphatic @entity3 , surgical procedure and survival rates of 366 @entity2220 @entity1 (from January 2007 to December 2013) with a @entity5 of 2.0 cm or less were analysed retrospectively. Among these @entity1 , 175 had a primary @entity5 with a diameter of 1.0 cm or less and 191 had a @entity5 of 1.1-2.0 cm. The survival of 366 @entity1 was evaluated by the restricted mean survival time (RMST) test, and the risk factors were assessed by multivariable analysis. RESULTS: Larger lesion had a significant relation to old age, male sex, preoperatively @entity787 ( @entity787 ) positive, invasive @entity420 (IAC) and advanced-stage disease (P < 0.0001, P = 0.001, P = 0.001, P < 0.0001 and P < 0.0001, respectively). @entity1 with @entity15709 ( @entity15709 )/minimally invasive @entity420 obtained a better prognosis than those with IAC (5-year overall survival rate: 98.5 vs 84.3%, P = 0.001; disease-related survival rate: 98.5 versus 85.2%, P = 0.001). The 5-year overall survival rates of @entity1 with a @entity5 less than 1.0 cm in comparison with 1.1-2.0 cm were 100.0 and 88.4% (P < 0.001), whereas the 5-year @entity2220 -specific survival rates were 100.0 and 89.0% (P < 0.001), respectively. Multivariable analysis for prognosis of @entity2220 @entity1 with a @entity5 2.0 cm or less in diameter revealed that histology, lymphatic @entity3 and advanced pathological stage affected the 5-year overall and disease-related survival rates unfavourably (P < 0.0001, 0.002, 0.001; and P < 0.0001, 0.005, 0.001, respectively), whereas @entity5 size did not have an obvious influence on survival. CONCLUSIONS: Micro-sized @entity2220 (1.0 cm or less) had specific clinical characteristics and more favourable survival rates. These @entity5 and a subtype of @entity15709 evaluated by computed tomography images or intraoperative frozen section may be appropriate candidates for a limited resection without mediastinal lymph node dissection.
