Interictal alterations of cardiovagal function in chronic XXXX .

@entity1 @entity129 @entity410 @entity302 @entity3174
AIM: To assess the function of parasympathetic heart control in @entity1 with @entity302 by means of clinical routine neurophysiology. MATERIALS AND METHODS: Seventy-one consecutive @entity302 @entity1 (mean age+/-S.D. 37.8+/-12.9 years) with partial or generalized @entity410 manifested for more than 6 months and receiving various therapeutic regimes and 71 matched for sex and age healthy controls undertook a battery of neurophysiological tests which consisted of sensory conduction of sural nerve; R-R interval variation during normal and deep breathing; Valsalva manoeuvre and tilt test for calculation heart rate changes to respiratory strain and standing. RESULTS: The @entity1 group showed a significant difference in all parasympathetic parameters studied compared to the control group. Overall, 42.2% of @entity1 had abnormal measurement in at least one of the parameters and Valsalva was the most frequently abnormal one (31% of @entity1 ). @entity129 was significantly lower in the @entity1 than in the controls and its measurements were associated with those of the tilt test. @entity302 (more than 10 years) and treatment with @entity3174 showed a negative effect on data of R-R interval variation during deep breathing. No other correlations between measurements of parasympathetic parameters and @entity302 related characteristics i.e. type and frequency of @entity410 , monotherapy or combined therapy with seven other antiepileptic medications, were proven. CONCLUSIONS: Our results suggested that simple neurophysiological tests, suitable for screening purposes were able to demonstrate suppressed cardiovagal control in @entity302 @entity1 and to identify those in need for further analysis of cardiovagal function.
