Unexpected @entity5 progression after conization for XXXX of the uterine cervix.

@entity1 @entity66 @entity2735 @entity5 @entity3
AIM: To determine the safety and usefulness of conization with an electrosurgical loop (the loop electrosurgical excision procedure [LEEP]) in young @entity1 with @entity2735 ( @entity2735 ) of the uterine cervix. METHODS: A retrospective medical chart review of five @entity1 with @entity2735 initially treated with LEEP conization between 2002 and 2010 and who later experienced recurrence in the form of invasive or advanced disease was conducted. RESULTS: The median @entity1 age at initial LEEP conization was 41years (33-56years). The margin status in conization specimens was positive in three of the five @entity1 . The median time to detection of @entity5 progression was 50months (17-58months). Magnetic resonance imaging was effective in detecting @entity5 recurrence in all cases. In four @entity1 , hysterectomy was performed to treat the recurrence; these four @entity1 are currently alive and disease-free. One @entity1 with cervical lymph nodes and bone @entity3 was treated with chemotherapy alone; however, the @entity1 died. In surgical specimens, @entity5 progression was observed extending toward the endometrium in all five @entity1 and toward the vagina in two @entity1 . CONCLUSION:     This study indicates that @entity1 with @entity2735 occasionally show unexpected @entity5 progression after conization and the progression could be life-threatening. @entity66 often shows @entity5 progression toward the endometrium or vagina, leading to difficulties in its detection at periodic pelvic examinations.
