[Third-line treatment of intermittent hepatic arterial infusion for unresectable liver XXXX from @entity14 ].

@entity1 @entity5 @entity14 @entity3
We report 6 cases of liver @entity3 from @entity14 with third-line treatment of intermittent hepatic arterial infusion and systemic chemotherapy for unresectable liver @entity3 with clinical signification of direct invasion to adjacent organs in Stage IV @entity14 . Subjects were 19 consecutive @entity1 who underwent R0 surgery to the @entity5 for @entity14 , pT4, M1 in 1995-2003. We studied the relationship of pathological invasion to adjacent organs of @entity5 to other clinicopathological factors to prognosis. Of the 19 @entity1 , 11 (57.8%) were R0 surgery to the @entity5 of @entity3 . Only 4 (36.7%) @entity1 survived more than 3 years. The @entity1 without excision did not survive for three years. The median survival time was only 8.5 months. Multivariate analysis indicated that only R0 surgery to the @entity5 of @entity3 was an independent prognostic factor. The optimum resection for adjacent organs may prolong a survival. But the extended resection is a possibility of shortening the survival time.
