[Application of immature platelet fraction   absolute immature platelet fraction and thrombelastograph on assessment of @entity548 risk in @entity1 with XXXX ].

@entity1 @entity548 @entity2416 @entity2704 @entity17792 @entity3039
OBJECTIVE: To explore the clinical value of immature platelet fraction   @entity2416   , absolute immature platelet fraction    A- @entity2416    and thrombelastograph   @entity17792    on assessment of @entity548 risk of @entity3039   . METHODS: two hundred and seventy- one @entity1 with @entity3039 were assessed based on @entity3039 -BAT @entity548 grading system. @entity2416 , @entity2416 were determined in 271 @entity1 , @entity17792 in 125 @entity1 . The correlations between @entity548 grades and @entity2416 , @entity2416 , variables of @entity17792 in subgroups were analyzed by statistical method. The predictive value of @entity2416 , @entity2416 , and variables of @entity17792 on @entity548 risk of @entity3039 @entity1 was evaluated. RESULTS: There were no significant differences in @entity548 degree in all @entity1 with different gender and disease stage   P>0.05   . Mild @entity548 rate in @entity1 was higher than that in adult   P<0.05   . PLT inversely correlated with @entity548 grade for the entire cohort   P<0.001   . In all subjects, PLT< 30*10   /L and pediatric cohorts with PLT< 30*10   /L, PLT were negatively correlated with @entity2416   P<0.05   , positive correlated with @entity2416   P<0.001   and the maximum amplitude   @entity2704      P<0.05   . Bleeding grades were significantly correlated with @entity2416 , @entity2416 , @entity2704 in all subjects and @entity1 with PLT< 30*10   /L   P<0.001   . @entity2416 , @entity2416 and @entity2704 did not correlate with @entity548 grades in @entity1 with PLT< 30*10   /L   P>0.05   . ROC curve analysis revealed @entity2416 , @entity2416 and @entity2704 had better predictive value   AUC 0.745, 0.744, 0.813, P<0.001   . Multivariate analysis showed that @entity2416 and @entity2704 were independence factors for predicting @entity548 risk in @entity3039 @entity1 and comprehensive predictive value was higher   AUC 0.846, P<0.001   than single variable. CONCLUSION: @entity2416 , @entity2416 and @entity2704 could accurately evaluate @entity548 risk inITP @entity1 . It may be considered as reference index of the treatment and observation index of curative effect.
