Impact of XXXX on hospital costs following the Norwood operation.

@entity1 @entity260
UNASSIGNED: Introduction @entity1 undergoing the Norwood operation consume considerable healthcare resources; however, detailed information regarding factors impacting hospitalisation costs is lacking. We evaluated the association of @entity260 with hospital costs. METHODS: In the present study, we utilised a unique data set consisting of prospectively collected clinical data from the Pediatric Heart Network Single Ventricle Reconstruction trial linked at the @entity1 level with cost data for 10 hospitals participating in the @entity1 's Hospital Association Case Mix database during the trial period. The relationship between complications and cost was modelled using linear regression, accounting for the skewed distribution of cost, adjusting for within-centre clustering and baseline @entity1 characteristics. RESULTS: A total of 334 eligible Norwood records (97.5%) were matched between data sets. Overall, 82% suffered from at least one complication (median 2; with a range from 0 to 33). Those with complications had longer postoperative length of stay (25 versus 12 days, p<0.001), more total ventilator days (7 versus 5 days, p<0.001), and higher in-hospital mortality (17.6 versus 3.4%, p<0.006). Mean adjusted hospital cost in those with a complication was  190,689 (95% CI  111,344- 326,577) versus  120,584 (95% CI  69,246- 209,983) in those without complications (p=0.002). Costs increased with the number of complications (1-2 complications= 132,800 versus 3-4 complications= 182,353 versus    5 complications= 309,372 [p<0.001]). CONCLUSIONS: This merged data set of clinical trial and cost data demonstrated that @entity260 are common following the Norwood operation and are associated with worse clinical outcomes and higher costs. Efforts to reduce complications in this population may lead to improved outcomes and cost savings.
