Exercise training in adults with @entity13785 : the effects on @entity158 , XXXX , and functioning.

@entity1 @entity1295 @entity13785 @entity74 @entity158
OBJECTIVE: To assess if a 12-week exercise intervention to improve aerobic fitness, muscle strength, and core stability also had an impact on @entity1295 , @entity158 , activity, and participation in adults with @entity13785 , an @entity74 . DESIGN: Open-label trial. Change was assessed by the chi-square test and Wilcoxon signed-rank test. SETTING: Physiotherapy practices. @entity1 : Mildly affected adult @entity1 with @entity13785 who were not dependent on ventilators and/or walking devices and were receiving enzyme replacement therapy. INTERVENTION: @entity1 participated in a 12-week exercise program, which included 36 sessions of standardized aerobic, resistance, and core stability exercises. MAIN OUTCOME MEASURES: Before and after the training program we evaluated @entity1295 (Fatigue Severity Scale), @entity158 (yes/no), motor function (Quantitative Muscle Function Test, Rasch-built Pompe-specific Activity Scale), amount of physical activity (activity monitor), and health status (Medical Outcomes Study 36-Item Short-Form Health Survey). RESULTS: Of the 25 @entity1 enrolled, 23 completed the program. At the end of the program, levels of @entity1295 (median, 5.33 to 4.78, P=.01) and @entity158 (56.5% to 21.7%, P=.04) improved. The quality of motor function and the amount of physical activity @entity1 engaged in did not change. Changes in @entity158 and @entity1295 were not related to improvements in aerobic fitness or muscle strength. CONCLUSIONS: This study in mildly affected adult @entity1 with @entity13785 suggests that a combined training program aiming to increase aerobic fitness, muscle strength, and core stability also leads to improvements in @entity1295 and @entity158 .
