International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for XXXX : the NMSQuest study.

@entity1 @entity66 @entity1109 @entity191 @entity892
@entity1109 ( @entity1109 ) of @entity191 ( @entity191 ) are not well recognized in clinical practice, either in primary or in secondary care, and are frequently missed during routine consultations. There is no single instrument (questionnaire or scale) that enables a comprehensive assessment of the range of @entity1109 in @entity191 both for the identification of problems and for the measurement of outcome. Against this background, a multidisciplinary group of experts, including @entity1 group representatives, has developed an @entity1109 screening questionnaire comprising 30 items. This instrument does not provide an overall score of disability and is not a graded or rating instrument. Instead, it is a screening tool designed to draw attention to the presence of @entity1109 and initiate further investigation. In this article, we present the results from an international pilot study assessing feasibility, validity, and acceptability of a nonmotor questionnaire (NMSQuest). Data from 123 @entity191 @entity1 and 96 controls were analyzed. @entity1109 were highly significantly more prevalent in @entity191 compared to controls ( @entity191 , median = 9.0, mean = 9.5 vs. control @entity1109 , median = 5.5, mean = 4.0; Mann-Whitney, Kruskal-Wallis, and t test, P < 0.0001), with @entity191 @entity1 reporting at least 10 different @entity1109 on average per @entity1 . In @entity191 , @entity1109 were highly significantly more prevalent across all disease stages and the number of symptoms correlated significantly with @entity66 . Furthermore, frequently, problems such as @entity892 , dribbling, apathy, blues, taste and smell problems were never previously disclosed to the health professionals.
