Changes in lipid metabolism and extension of XXXX .

@entity1 @entity28 @entity1674 @entity1151 @entity1150 @entity412 @entity4977 @entity209 @entity1211 @entity165
BACKGROUND/AIMS: @entity1150 ( @entity1150 ) and @entity1151 ( @entity1151 ) are common diseases with a vast number of acquired and congenital risk factors. @entity4977 are not established risk factors for @entity1211 ( @entity1211 ) so far. However, in recent literature, associations between @entity1211 and the @entity209 , especially with elevated lipid parameters, have been described. The aim of our study was to investigate the association between the extension of @entity1211 and changes in the lipid profile. METHODS: We included 178 @entity1211 @entity1 in our study; 59 @entity1 had isolated @entity1151 , 39 @entity1 had isolated @entity1150 of the leg and 80 @entity1 had both ( @entity1150 and @entity1151 ). Concerning @entity1151 , we distinguished between massive and submassive @entity1151 . We evaluated plasma lipids and lipoproteins in @entity1151 and @entity1150 @entity1 as well as in massive and submassive @entity1151 @entity1 . RESULTS: @entity1151 @entity1 had higher levels of plasma @entity1674 [median (interquartile range): 162 (109-254) vs. 136.5 (96.5-162) mg/dl, p = 0.047] and lower levels of high-density lipoprotein @entity165 (HDL-C; 52.1    17.2 vs. 63.9    22.7 mg/dl, p = 0.004) than @entity1150 @entity1 . Furthermore, @entity1151 @entity1 were significantly older than @entity1150 @entity1 (59.6    16.9 vs. 52.2    15.5 years, p = 0.02). We were not able to find differences in lipid parameters in @entity1 with massive @entity1151 compared to those with submassive @entity1151 . However, @entity1 with massive @entity1151 were more @entity28 than @entity1 with submassive @entity1151 (body mass index 29.1    4.6 vs. 26.9    4.9, p = 0.012). CONCLUSIONS: Lipid parameters and lipoproteins differ between @entity1150 and @entity1151 @entity1 . @entity1151 @entity1 had higher @entity412 and lower HDL-C levels compared with @entity1150 @entity1 .
