Ratio of metastatic lymph nodes is more important for XXXX @entity1 treated with preoperative chemoradiotherapy.

@entity1 @entity5 @entity1600 @entity477 @entity3121 @entity1349
AIM: To evaluate the predictive value of the @entity1600 ( @entity1600 ) ratio (LNR, number of metastatic LNs/ examined LNs) for recurrence in @entity1 with @entity5 and to compare its applicability according to preoperative chemoradiotherapy (PCRT). METHODS: From 2000 to 2009, 967 @entity1 with metastatic LNs after curative resection for locally advanced @entity5 were identified. @entity1 were categorized according to PCRT (PCRT vs No PCRT). The cut-off LNR was determined based on the @entity3121 vs @entity477 when the recommended number of LNs was harvested. The 5-year @entity1349 ( @entity1349 ) rates using the Kaplan-Meier method were compared according to p/yp N stage and the LNR in each group. RESULTS: Among @entity1 with the same p/ypN stage, the 5-year @entity1349 rate differed according to the LNR. In addition, the 5-year @entity1349 rate was significantly different between pN and LNR groups in @entity1 with No PCRT. In PCRT group, however, only LNR was associated with prognosis. On multivariate analysis, both pN and LNR were significant independent prognostic factors for 5-year @entity1349 in the No PCRT group. In the PCRT group, only LNR category was found to be associated with @entity1349 (HR = 2.36, 95%CI: 1.31-3.84, and P = 0.001). CONCLUSION: The LNR is an important prognostic predictor of @entity1349 in @entity5 @entity1 especially treated with PCRT. Current pN categories could not discriminate between prognostic groups of @entity1349 after PCRT.
