Iatrogenic painful XXXX .

@entity1 @entity29222 @entity5 @entity16 @entity128 @entity305 @entity158 @entity9
It is estimated that at least one out of four @entity1 with @entity5 complains of @entity158 originating from @entity128 . @entity128 may result from direct invasion/compression by @entity5 , or by remote effect of the @entity5 such as @entity29222 . In many cases, the @entity128 is caused by medical therapy, or surgical interventions. @entity158 generated by drugs or medical acts is called iatrogenic. A common @entity9 is chemotherapy induced painful @entity305 . This @entity16 typically affects mostly the small myelinated and unmyelinated nerve fibres. Surgical and anaesthesiological interventions also frequently cause direct nerve stretch or section. Some interventions, particularly those requiring extended resection, have a higher incidence of @entity158 . Limb and colon amputation, nerve dissection, mastectomy and thoracotomy are the most common interventions for @entity5 known to cause @entity128 . As @entity158 clinicians, we focus attention on the painful consequences of surgical interventions because there is evidence that a more accurate surgical approach and possibly a prophylactic prevention of the @entity9 may reduce the @entity158 .
