[A role of long-term stress and functional properties of the endothelium in the development of XXXX ].

@entity1 @entity409 @entity148 @entity3519 @entity1642 @entity65
AIM: To study a role of long-term stress and endothelial function in the development of @entity3519 ( @entity3519 ) in young @entity1 . MATERIAL AND METHODS: Authors examined 75 male @entity1 , aged from 17 to 28 years, with @entity3519 including 41 @entity1 without clinically evident symptoms of @entity1642 (group I) and 34 @entity1 with high level of @entity1642 (group II). A comparison group consisted of 21 healthy volunteers. The level of @entity148 was assessed using the Spilberger-Khanin Inventory and the functional state of endothelium with the use of endothelium-dependent vasodilatation (EDV). Standard bicycle physical exercise (PE) test was performed. RESULTS: Correlations between state and trait @entity148 in all groups were shown. In group II, these values were maximal thus demonstrating marked @entity148 . In EDV and PE tests, @entity1 of group I had general reactivity of the vascular wall, while @entity1 of group II showed opposite reactions, either increase or decrease in the brachial artery diameter. This instability may result from the increased liability of the sympathetic part of the autonomic nervous system in stress conditions. CONCLUSION: Long-term stress causes vascular @entity409 in young @entity1 with @entity3519 that increases the severity of clinical manifestations of the disease and leads to the increased risk of @entity65 .
