XXXX of the bile ducts: A case report and literature review.

@entity1 @entity3883 @entity4929 @entity5 @entity409 @entity1126 @entity281 @entity2877
@entity4929 of the bile duct (IPNB) is a rare @entity1126 mostly found in far eastern nations where hepatolithiasis and @entity281 are endemic. In western countries, it is very rare and the etiology is unknown. In this article, we report the first IPNB @entity1 we encountered in our clinic and a literature review. The @entity1 is a 38-year-old female with a history of @entity2877 who presented with @entity3883 . She was found to have a papillary mass at the junction of the right hepatic duct and common hepatic duct with six masses in the @entity409 . The immunophenotypic and histologic features of the @entity5 are consistent with IPNB, gastric subtype. The @entity1 had a partial hepatectomy and has been receiving palliative chemotherapy. In a search of PubMed database, we collected 354 IPNB @entity1 reported in 22 articles. In these @entity1 , 52.8% were from Japan and 27.7% were from western countries including the United States (11.0%). The age of the @entity1 ranged from 35 to 80 years old with an average of 64.6. Male/female ratio was 1.5. Macroscopically, 57.5% of the @entity5 were in the left lobe and 29.5% were in the right lobe. The average size of the @entity5 were 4.2 cm at the time of diagnosis. Histologically, pancreato-biliary subtype accounted for 41.8%, intestinal 28.0%, gastric 13.5% and oncocytic 16%. An invasive component is most often present in the pancreato-biliary and gastric subtypes. Despite recent advanced technologies, diagnosis of IPNB is still challenging, especially in western countries due to its rarity. Defined clinico-pathologic features are in demand for the accurate diagnosis and proper treatment.
