[Assessment of short-term effects of awareness programs and XXXX therapy on subjects from private clinics at high risk for cardiovascular disease].

@entity1 @entity753 @entity301 @entity11429 @entity8673
PURPOSE: To evaluate short-term efficacy of awareness programs (AP) in reducing @entity301 ( @entity301 ). METHODS: High risk @entity753 @entity1 were divided in 2 groups during 16 weeks. Group A (n = 417, 54.3 +/- 10.0 years, 55% males) received verbal and written orientation on @entity301 control, and group B (n = 180, 54.4 +/- 10.9 years, 45% males) received only verbal orientation. All @entity1 received @entity8673 10 mg q.d. for 12 weeks. The evolution of body weight, arterial pressure, lipid profile, Castelli's I and II indexes (TC/HDL and LDL/HDL), and Framingham scores were evaluated. RESULTS: At baseline, A had a lower HDL-C (40.0 +/- 11.0 vs 43.0 +/- 11.0 mg/dl, p = 0.013) and a higher index I (8.2 +/- 3.0 vs 7.6 +/- 2.3, p = 0.008) than B. After 16 weeks, A had greater change than B in TC (-28.0 vs -25.0, p < 0.05), @entity11429 (-29.0 vs -27.6, p < 0.05), HDL-C levels (+13.7 vs +10.8, p < 0.05) and in the Castelli's Index (-39.0 vs -33.0; p < 0.05). In both groups @entity8673 use potentialized the effects of diet on the lipid profile. CONCLUSION: The AP seemed to be more effective than verbal orientation alone in @entity301 reduction at short-term.
