Establishment of Reference Ranges for Prostate Volume and Annual Prostate Volume Change Rate in Korean Adult XXXX : Analyses of a Nationwide Screening Population.

@entity1 @entity263 @entity1069 @entity1486
We aimed to determine normal reference ranges for @entity1069 ( @entity1069 ) and annual @entity1069 change rate in a Korean nationwide screening population. Data from @entity1 who underwent a routine health check-up were collected from 13 university hospitals. The cohort comprised @entity1 aged >= 40 yr who had undergone 2 or more serial transrectal ultrasonographies. @entity1 with initial @entity1069 >100 mL; serum PSA level>10 ng/mL; @entity1069 reduction>20% compared with initial @entity1069 , or who had history of @entity263 or prostate surgery, were excluded. Linear regression and mixed effects regression analyses were used to predict mean @entity1069 and longitudinal change in @entity1069 over time. A total of 2,967 @entity1 formed the study cohort. Age, body mass index (BMI), and serum @entity1486 (PSA) level were found to be significant predictors of @entity1069 . A predicted @entity1069 table, with a 95% confidence interval (CIs), was developed after adjusting for these 3 variables. Annual @entity1069 change rate was 0.51 mL/year (95% CI, 0.47-0.55). Annual @entity1069 change rate according to age was 0.68 mL/year, 0.84 mL/year, 1.09 mL/year, and 0.50 mL/year for subjects in their 40s, 50s, 60s, and >= 70 yr, respectively. Predicted annual @entity1069 change rate differed depending on age, BMI, serum PSA level and baseline @entity1069 . From a nationwide screening database, we established age-, PSA-, and BMI-specific reference ranges for @entity1069 and annual @entity1069 change rate in Korean @entity1 . Our newly established reference ranges for @entity1069 and annual @entity1069 change rate will be valuable in interpreting @entity1069 data in Korean @entity1 .
