Lower-limb MRI in the staging and re-staging of osteonecrosis in paediatric @entity1 affected by XXXX after therapy.

@entity1 @entity981 @entity75 @entity7730 @entity85
PURPOSE: To assess the diagnostic value of MRI examination in detecting and monitoring @entity75 ( @entity75 ) in childhood @entity981 ( @entity981 ) after @entity7730 ( @entity7730 ) and/or bone marrow transplantation (BMT). METHODS AND MATERIALS: Seventy-three @entity1 (37 males, mean age 12.4 years old) with @entity981 after treatment underwent a lower-limb MR examination between November 2006 and March 2012. In 47 there was clinical suspicion of @entity75 , 26 were asymptomatic. Studies were performed with a 1  T and a 1.5  T scanner, acquiring short tau inversion recovery (STIR) and T1-weighted sequences in coronal plane from the hips to the ankles. The average acquisition time was 18  min. Considering baseline and follow-up examinations, the overall number of MRI studies was 195. RESULTS: Fifty-four of 73 @entity1 showed @entity75 at MRI study, with an overall number of 323 @entity75 (89 involving articular surface, 24 with @entity85 , JD). Twenty-five of 47 symptomatic @entity1 showed @entity75 , 11 developed JD. Three of 26 asymptomatic @entity1 showed subchondral bone @entity75 at baseline examination but no JD at follow-up. Twenty-two of 28 BMT, 32/45 @entity7730 @entity1 developed @entity75 . CONCLUSION: Our MRI protocol proved to be feasible in evaluating @entity75 in paediatric @entity1 . Studies should be addressed only to symptomatic @entity1 .
