Comparison between fragmented QRS versus Q wave in XXXX detection using myocardial perfusion single photon emission computed tomography.

@entity1 @entity583 @entity296 @entity453
BACKGROUND: Accurate diagnosis of @entity583 ( @entity583 ) is of paramount importance in @entity1 management which necessitates the development of efficient as well as accurate diagnostic methods. Q wave is not present in all @entity1 with @entity583 and its prevalence is declining. Recently, fragmented QRS (Fqrs) complex has been introduced as a marker of prior @entity583 . In this study, we intended to investigate diagnostic value of fQRS compared to Q wave. METHODS: We included 500 consecutive @entity1 with known or suspected @entity453 ( @entity453 ) who underwent two days gated myocardial perfusion imaging (MPI) using Dipyridamole pharmacologic stress. ECG was evaluated to detect fQRS as well as Q-Wave. Finally, subjects were compared in terms of ventricular perfusion and function indices. RESULTS: 207 @entity1 and 269 @entity1 with mean age of 57.06  12 years were studied. ECG analysis showed that 14.3% of the @entity1 had both fQRS and Q waves, 30.7% had fQRS and 3.8% had Q waves. Fixed myocardial perfusion defect was noted in 22.3% of @entity1 according to MPIs. Sensitivity, specificity, positive and negative predictive values for @entity296 detection were 78%, 65%, 39% and 91% respectively for fQRS and 61%, 94% , 76% and 89% for Q wave. CONCLUSIONS: Although fQRS had lower specificity compared to Q wave in the detection of @entity296 , due to higher sensitivity and negative predictive value can be an invaluable diagnostic index. There is also an incremental value for fQRS in association with Q-wave in @entity296 assessment.
