Necrotizing XXXX caused by disseminated @entity281 after orthotopic liver transplantation.

@entity1 @entity82 @entity198 @entity548 @entity2379 @entity4 @entity16 @entity2381 @entity364 @entity281 @entity3851 @entity5074
Liver transplantation is the only available treatment for some @entity1 with @entity3851 . Despite reduction in mortality rates due to advances related to surgical techniques, intensive medical management and immunosuppressive therapy, invasive @entity364 remain a serious complication in orthotopic liver transplantation. We report the case of an 18-year-old male diagnosed with @entity82 in 2009 who was assessed and listed for liver transplantation for massive @entity548 . One year after listing a successful orthotopic liver transplantation was performed. Uneventful early recovery was achieved; however, he developed @entity16 23 and 40 days after surgery, respectively. Antibiotic therapy with @entity5074 and @entity2379 was started early, with no major response. Neuroimaging revealed multiple right frontal and right parietal lesions with perilesional @entity4 ; surgical management of the brain abscesses was performed. A biopsy with periodic acid-Schiff and Gomori stains revealed areas with mycotic microorganisms morphologically consistent with Aspergillus, later confirmed by culture. The @entity1 developed necrotizing @entity198 secondary to @entity2381 and died. Necrotizing @entity198 as a clinical presentation of @entity281 in an orthotopic liver transplant is not common, and even with adequate management, early diagnosis and prompt antifungal treatment, mortality rates remain high.
