The MacNew XXXX health-related quality of life instrument: a summary.

@entity1 @entity712 @entity301 @entity951 @entity299 @entity583
BACKGROUND: The measurement of health, the effects of disease, and the impact of health care include not only an indication of changes in disease frequency and severity but also an estimate of @entity1 ' perception of health status before and after treatment. One of the more important developments in health care in the past decade may be the recognition that the @entity1 's perspective is as legitimate and valid as the clinician's in monitoring health care outcomes. This has lead to the development of instruments to quantify the @entity1 ' perception of their health status before and after treatment. METHODS: We review evidence supporting the measurement properties of the MacNew @entity299 Health-related Quality of Life [MacNew] Questionnaire which was designed to evaluate how daily activities and physical, emotional, and social functioning are affected by @entity301 and its treatment. RESULTS: Reliability was demonstrated by using internal consistency and the intraclass correlation coefficients for the three domains in the Dutch, English, Farsi, German, and Spanish versions of the MacNew. With internal consistency and intraclass correlation coefficients =>0.73, reliability is high. Validity of the MacNew was examined with factor analysis and three core underlying factors, physical, emotional, and social, were identified, explaining 63.0 - 66.5% of the observed variance and replicated in the translations with psychometric data. Construct validity of the MacNew was further demonstrated by extensive substantiation of the logical relationships, defined a priori, between items and other comparison tools. The MacNew is responsive and sensitive to changes in HRQL following various interventions for @entity1 with @entity299 with 11 of 13 effect size statistics >0.80. Taking an average of 10 minutes or less to complete, the respondent-burden for the MacNew is low and its acceptability is demonstrated by response rates of over 90%. Normative data are available for @entity1 with @entity583 , @entity951 , and @entity712 in the English version. CONCLUSION: The MacNew may be a valuable tool for assessing and evaluating health related quality of life in @entity1 with @entity299 .
