Preoperative XXXX in oral surgery: a method of choice in controlling postoperative pain.

@entity1 @entity117 @entity1337 @entity5834 @entity158 @entity8726 @entity10425 @entity71022
The analgesic efficacy of a single 50-mg preoperative dose of @entity8726 was compared with @entity71022 ( @entity117 375 mg, @entity10425 30 mg, @entity5834 30 mg) and a placebo. Forty @entity1 scheduled for the surgical removal of impacted maxillary third molars were enrolled in a double-blind, randomized study. Using a within-subject design we compared the analgesic efficacy of (1) preoperative @entity8726 50 mg with placebo in 20 @entity1 , and (2) preoperative @entity71022 with placebo in 20 other @entity1 . Using a between-group design, we then compared the analgesic efficacy of (3) each drug given preoperatively and postoperatively, and (4) each drug given postoperatively only. @entity1 rated 2 @entity158 dimensions, intensity and unpleasantness, hourly for 8 hours after the presurgical dose. The results of this study indicate that better @entity1337 was obtained when @entity8726 was given preoperatively compared to only after surgery. Conversely, preoperative administration of @entity71022 did not demonstrate any significant influence on postsurgical @entity1337 . When comparing the 2 drugs, @entity8726 proved to be superior in providing @entity158 relief only when it was given prior to surgery. There was no difference between them when given only after surgery. Side effects were moderate and not significantly different between @entity1 receiving @entity8726 and those receiving @entity71022 .
