Weaning affects the expression of XXXX proteins in different regions of the gastrointestinal tract of piglets.

@entity19457 @entity1707 @entity1457 @entity19456 @entity4229
@entity1457 proteins (HSP) play a central role in the protection of cells, tissues or organs subjected to various types of stressors. Different nutrients have been recently shown to exert their protection through the induction of HSP. Because these nutrients alleviate alterations of the intestine after weaning in @entity1707 , this study was designed to obtain basic information on the expression of @entity19456 , @entity1457 cognate 70 (HSC 70), @entity19457 and @entity4229 along the gastrointestinal tract (GIT) of young @entity1707 and to study the effect of weaning on this expression. @entity1707 were weaned at 28 or 21 d and slaughtered at various times postweaning. All HSP were expressed in the GIT segments studied before and after weaning. However, the expression of @entity19456 and @entity19457 was transiently increased in the stomach and duodenum between 6 and 12 h postweaning and between 24 and 48 h in the mid-jejunum, ileum and colon. Their expressions were transiently decreased in the ileum. Expression of @entity4229 increased in the stomach and jejunum but decreased in the duodenum, ileum and colon. Similar results were obtained at both ages of weaning. We conclude that the HSP studied are present all along the gut of @entity1707 and that their expression is modulated through weaning according to spatial-temporal patterns. The modulation by nutrients of HSP and their protective role on the GIT remain to be investigated in @entity1707 .
