[Broncho-alveolar lavage in pulmonary involvement in XXXX ].

@entity1 @entity5641 @entity5924 @entity505 @entity401 @entity309
This study was designed to investigate by bronchoalveolar lavage (BAL) the characteristics of lung involvement in @entity309 ( @entity309 ). Twenty six @entity1 with @entity309 were included; ten were active smokers. Chest X Ray, pulmonary function tests and BAL were performed in all @entity1 . @entity5924 was found in 7% of cases, @entity5641 in 30% of cases. 83% of @entity1 were found to have diffuse alveolar and/or @entity401 , 17% rheumatoid nodules. Functional evaluation showed a restrictive pattern and a significant reduction in the @entity505 monoxyde diffusing capacity. Smokers had elevated BAL macrophages and decreased lymphocytes compared with non-smokers: respectively 89% vs 62.9% and 7.3% vs 18.9%. @entity1 with @entity5924 had lower FVC than others: 38 +/- 14% vs 61 +/- 3%, and their BAL neutrophils were increased: 71 +/- 23% vs 7.5 +/- 2%. There was an inverse correlation between neutrophil counts and FVC in non-smokers, and diffusing capacity. We conclude that BAL inflammatory cells profiles are abnormal in @entity309 and modified by a smoking history and the existence of a @entity5924 .
