[Radiotherapy after chemotherapy and second-look laparotomy in the treatment of advanced XXXX ].

@entity43 @entity1 @entity66 @entity41 @entity5 @entity900
In order to better assess the place of abdominopelvic irradiation after chemotherapy in the treatment of advanced @entity43 , the survival times in 25 @entity1 treated from 1976 to 1986 were examined. 2 stage IIc, 18 stage III and 4 stage IV were treated. Treatment included chemotherapy (with @entity900 in 16/25 cases) and a second-look laparotomy. 12 @entity1 had only microscopic @entity41 , 5 had macroscopic @entity5 less than 2 cm, and 8 @entity1 had no detectable @entity41 . A whole abdomen irradiation of 22.50 Gy with a pelvic boost to 45 Gy was also performed. Actuarial 3-year survival was 58% for the entire population. 10 loco-regional relapses were observed. The 3-year-actuarial survival was 71% for stage III @entity1 . Haematologic tolerance of irradiation was poor with only 17 @entity1 (68%) receiving the complete dose of irradiation. One late grade 3 intestinal complication was observed. These results and others previously published, suggest that abdominal irradiation is valuable in the treatment of advanced @entity43 for stage IIc or III @entity1 without macroscopic @entity66 after chemotherapy and second-look laparotomy.
