Extent of Contrast Enhancement on Non-Enhanced Computed Tomography after Intra-Arterial Thrombectomy for Acute Infarction on Anterior Circulation: As a Predictive Value for Malignant XXXX .

@entity1 @entity510 @entity2657 @entity385
OBJECTIVE: To determine whether the use of contrast enhancement (especially its extent) predicts @entity2657 after intra-arterial thrombectomy (IAT) in @entity1 with acute @entity385 . METHODS: We reviewed the records of @entity1 with acute @entity385 who underwent IAT for occlusion of the internal carotid artery or the middle cerebral artery between January 2012 and March 2015. To estimate the extent of contrast enhancement (CE), we used the contrast enhancement area ratio (CEAR)-i.e., the ratio of the CE to the area of the hemisphere, as noted on immediate non-enhanced brain computed tomography (NECT) post-IAT. @entity1 were categorized into two groups based on the CEAR values being either greater than or less than 0.2. RESULTS: A total of 39 @entity1 were included. Contrast enhancement was found in 26 @entity1 (66.7%). In this subgroup, the CEAR was greater than 0.2 in 7 @entity1 (18%) and less than 0.2 in the other 19 @entity1 (48.7%). On univariate analysis, both CEAR >= 0.2 and the presence of @entity510 were significantly associated with progression to @entity2657 (p<0.001 and p=0.004), but on multivariate analysis, only CEAR >= 0.2 showed a statistically significant association (p=0.019). In the group with CEAR >= 0.2, the time to @entity2657 was shorter (p=0.039) than in the group with CEAR <0.2. Clinical functional outcomes, based on the modified Rankin scale, were also significantly worse in @entity1 with CEAR >= 0.2 (p=0.003). CONCLUSION: The extent of contrast enhancement as noted on NECT scans obtained immediately after IAT could be predictive of @entity2657 and a poor clinical outcome.
