@entity9205 and A Preoperative Serum Levels Predict Nodal and Distant @entity3 in Differentiated XXXX @entity1 .

@entity1 @entity878 @entity7 @entity5 @entity3658 @entity877 @entity9205 @entity3 @entity259
BACKGROUND: Preoperative @entity5 aggressiveness biomarkers may help surgeons decide the extent of an operation. However, whether serum angiogenetic factors can be used to predict the prognosis of @entity1 with differentiated @entity259 is still unclear. METHODS: Seventy-six DTC @entity1 were prospectively recruited. Preoperative serum samples were collected and measured for @entity878 , @entity3658 , @entity877 , @entity7 , and @entity9205 levels. The potential correlations between their serum levels and clinicopathologic features as well as their prognoses were analyzed. RESULTS: Older age (>45 years old) and higher @entity7 serum levels were independent predictors of extrathyroidal extension. The @entity9205 serum level was an independent factor for lymph node @entity3 and @entity7 was an independent factor for distant @entity3 . None of these serum angiogenetic factors were significantly different between @entity1 who were disease free and those with recurrences. The presence of lymph node @entity3 was the only independent factor for recurrence over the 2-year follow-up. CONCLUSION: Preoperative serum @entity7 and @entity9205 levels were significantly elevated in DTC @entity1 with distant and lymph node @entity3 . These findings, when combined with other clinicopathological factors, may help in surgical decisions.
