Effects of XXXX on healing in microvascular @entity254 .

@entity1 @entity5 @entity254 @entity1398 @entity35 @entity5713
Reconstructive microsurgical procedures are getting more common in @entity5 @entity1 . Adjuvant therapies, such as chemotherapy, radiotherapy, and immune therapy, are usually combined with surgical approaches to improve outcomes. This study was designed to investigate the effects of preoperative chemotherapy on healing in microvascular @entity254 . As a commonly preferred drug for neoadjuvant @entity5 treatment, @entity5713 was used on @entity35 in our study. Ninety-three @entity35 were used and randomly allocated into two groups as 72 experimental and 21 control @entity35 . @entity5713 2 mg/kg was administered as a single dose intraperitoneally on day 0 in the experimental group. Leukocytes and erythrocytes were counted on days 0, 1, 3, 5, 7, 10, and 15 in 6 @entity35 of the experimental and 6 @entity35 of the control group. We found that the @entity1398 period ended on approximately day 7. After applying the medication, the experimental group (n = 72) was divided into three main groups (n = 24). We performed end-to-end femoral artery @entity254 on days 7 or 14 or 21, respectively, in each group. Each main group was divided into three subgroups (n = 8), and then we tested patency and took biopsies on days 7 or 14 or 21, respectively, in each subgroup. Histopathologic evaluation was carried out. The comparison of patency tests and pathologic examination indicated that there was no statistically significant difference between the two groups.
