Risk factors in pediatric shrimp XXXX .

@entity1 @entity20301 @entity484 @entity566 @entity113 @entity110 @entity2021
BACKGROUND: The prevalence of @entity20301 @entity566 is    1.3% in the United States, with shrimp most commonly reported. Shellfish is one of the top causes of food-induced anaphylactic reactions, yet there are no reported rates of pediatric shrimp @entity2021 in the literature. In previously reported adults with shrimp @entity566 , the rate of @entity2021 to shrimp was 42%. OBJECTIVE: To describe the rate of @entity2021 among @entity1 with shrimp @entity566 , demographics, clinical presentation, and cross-reactive sensitization. METHODS: Retrospective chart review of @entity1  <=18 years old who presented with shrimp @entity566 to Texas @entity1 's Hospital Allergy and Immunology Clinic over 11 years. RESULTS: Sixty-eight @entity1 were identified with shrimp @entity566 (61% male, 39% female), with a median age of diagnosis at 5.6 years (range, 0.96-16.6 years). The rate of @entity2021 was 12%, and mucocutaneous symptoms were most common (skin symptoms, 70%; @entity110 , 58%; and @entity113 , 58%). No factors were positively associated with @entity2021 , whereas @entity1 without @entity2021 had a significantly higher rate of @entity484 compared with those with @entity2021 (p = 0.02). African Americans and Asian Americans were disproportionately affected (p < 0.001). There were low rates of cross-sensitization for other crustaceans and for mollusks (57% and 26%, respectively). CONCLUSION: The rate of @entity2021 to shrimp was significantly lower in @entity1 with shrimp @entity566 than in adults, and anaphylactic reactions were negatively associated with @entity484 . Cross-reactivity to other crustaceans and mollusks does not uniformly occur. Prospective studies with double blinded placebo-controlled food challenges are needed to further characterize @entity1 with shrimp @entity566 .
