Cardiac troponin I: a reliable marker and early @entity296 with @entity5422 after fatal enterovirus-71 XXXX .

@entity1 @entity4767 @entity296 @entity63 @entity75 @entity5422 @entity5825 @entity6949 @entity551 @entity281 @entity299 @entity204 @entity5826
OBJECTIVES: A major outbreak of enterovirus 71 (EV71) in Taiwan in 1998 caused many severe cases and 78 @entity204 . Our purpose was to find reliable markers and early indicators of @entity4767 . METHODS: From June 2000 to November 2001, 21 @entity1 with @entity5825 or @entity5826 with CNS @entity281 were admitted to Kaohsiung Veterans General Hospital. All 21 had culture-confirmed EV71 @entity281 or were EV71 IgM positive. @entity1 were divided into two groups: group I included the five fatalities at our institution and group II, the 16 surviving @entity1 . RESULTS: Of the 21 @entity1 and @entity1 with EV71 @entity281 with CNS involvement, MR imaging studies were completed on 17, and 15 showed hyperintensity in the posterior portions of brain stem. All @entity1 received intravenous immunoglobulin (IVIG) 1 g/day for two days and supportive care. Five @entity1 rapidly deteriorated owing to irreversible @entity551 and died. The other 16 @entity1 recovered completely without sequel. In group I @entity1 , the decrease of cardiac ejection function is significant and laboratory findings showed lower platelet count (P=0.0192). The mean of initial @entity6949 level for groups I and II was 10.6+/-11.6 and 0.48+/-0.55 ng/dl, respectively, higher in group I than in II (P=0.0019). CONCLUSION: We hypothesized that like @entity1 with severe burns, those with severe EV-71 CNS @entity5422 have varying degrees of non- @entity63 @entity299 , manifesting as leakage of @entity6949 from myocytes into the circulation. EV-71 CNS @entity5422 likely to die with an early @entity296 evidenced by reduced ejection fraction and release of @entity6949 . We conclude that fatal EV71 CNS @entity281 quickly leads to @entity204 due to severe @entity75 associated with @entity296 .
