Role of XXXX and alpha-globulins in differentiating @entity1294 .

@entity1 @entity650 @entity32 @entity303 @entity1294 @entity195 @entity1851
BACKGROUND: Inflammatory mechanisms and immune activation have been hypothesized to play a role in the pathogenesis of age-associated diseases, including @entity195 . PURPOSE: The evaluation of inflammatory markers in @entity1 with @entity303 , and to determine whether these markers can be used to differentiate between @entity1294 ( @entity1294 ) and @entity195 ( @entity195 ). @entity1 AND METHODS: Twenty demented @entity1 (10 @entity195 and 10 @entity1294 ) and 20 non-demented controls were subjected to clinical evaluation, MRI brain scans and laboratory tests, including @entity650 , @entity1851 and serum protein electrophoresis. RESULTS: The results of this study revealed that serum levels of @entity650 and @entity1851 were significantly elevated among @entity1 with both types of @entity303 compared to normal elderly subjects. Although the mean @entity650 level was higher in @entity1 with @entity195 compared to @entity1 with @entity1294 , this difference was not significant. The cutoff value at which the serum level of @entity650 gave maximum sensitivity and specificity was 14.25 pg/ml. Moreover, a   - and a   -globulins were able to discriminate between @entity195 and @entity1294 (being significantly higher in @entity195 ). CONCLUSION: @entity650 levels could be used to differentiate @entity303 from normal aging. Moreover, a   - and a   -globulins could differentiate between @entity195 and @entity1294 . It can be concluded that @entity32 plays an important role in both types of @entity303 .
