Long-term follow-up of the first successful bone marrow transplantation in XXXX .

@entity1 @entity73 @entity19831 @entity764 @entity1120 @entity629
A 9-year-old @entity1 with @entity1120 underwent splenectomy and allogeneic bone marrow transplantation. Her HLA-identical brother with normal @entity629 -beta-glucosidase activity served as donor. One month after transplantation, @entity629 -beta-glucosidase activity in the lymphocytes were normal. Plasma glucosylceramide normalized already after splenectomy and further decreased after marrow transplantation. @entity19831 in the erythrocytes was normal around a year after transplantation. The enlarged liver normalized in size by 2 years. Gaucher cells were still present in the bone marrow 1 year after transplantation but had completely disappeared at 3 years. The @entity1 has grown 29 cm during the 5 years that have passed after transplantation compared to 1 cm/year during 3 years before. The @entity1 has a @entity73 , and @entity764 have appeared. Wechsler intelligence scale performance has slowly decreased after transplantation. This may be caused by continued neuronal storage of @entity19831 . Otherwise, this @entity1 is active and healthy 5 years after bone marrow transplantation.
