[Olfactory neuroblastoma ( XXXX ): etiopatogenesis, diagnosis, and treatment].

@entity2828 @entity706 @entity5 @entity1415 @entity4236 @entity2875 @entity4838 @entity320 @entity19534
INTRODUCTION: @entity4236 is a @entity5 arising from the olfactory epithelium located in the upper part of the nasal cavities. Recent clinical and preclinical studies shed more light on etiopathogenesis, diagnosis, and treatment of this rare malignancy. MATERIAL AND METHODS: A systematic review of PubMed/Medline and available Polish literature. RESULTS: Molecular studies indicate basal progenitor cells of the olfactory epithelium as the origin of @entity4236 . @entity5 symptoms are related to its location and typically include: @entity1415 , @entity4838 as well as @entity19534 . @entity4236 should be differentiated from @entity2875 , @entity2828 , @entity320 , @entity706 , and pericytoma. A combination of surgery and radiotherapy seems to be the optimum approach to treatment. More aggressive treatment regimens are promising but require further studies. CONCLUSIONS: @entity4236 is a rare @entity5 arising from the olfactory epithelium. Early diagnosis and interdisciplinary approach to treatment is vital in the management of the @entity5 .
