[Nutritional Therapy for XXXX and Adolescents with Autism Spectrum Disorders: What is the Evidence?]

@entity1 @entity717 @entity72 @entity2438
UNASSIGNED: Background: @entity72 ( @entity72 ) are a group of @entity717 in childhood and adolescence. Beside genetic predisposition also environmental influences may contribute to the @entity2438 pathogenesis. Family members of @entity1 and adolescents with @entity2438 often ask for specific diets to alleviate @entity2438 -associated symptoms. The aim of this review is to provide evidence-based data on nutritional interventions for @entity1 and adolescents with @entity2438 , thus enabling practitioners to competently assess these diets. Methods: Applying defined inclusion and exclusion criteria, a systematic literature research in PubMed, Cinahl and The Cochrane Library was conducted. Studies published earlier than 1999 were excluded. Study quality was assessed by using the CONSORT, STROBE or PRISMA checklist, respectively. Results: 12 randomised controlled studies and 2 non-controlled studies could be included in the evaluation (n=971). There is no proven efficacy of the widely used gluten-free casein-free diets (GFCF), and no respective predictive marker has been proven significant. Conclusion: Based on available data, no evidence based recommendations regarding nutritional interventions for @entity1 and adolescents with @entity72 can be made. Future studies need to clarify whether particular @entity1 may yet benefit from certain diets.
