Jones criteria and underdiagnosis of XXXX .

@entity4789 @entity1 @entity883 @entity339 @entity625 @entity4790 @entity337 @entity2720 @entity4841
OBJECTIVE: The authors attempt to determine whether typical clinical and laboratory manifestations of @entity4789 ( @entity4789 ) are in accordance to what has been traditionally described and how useful the Jones criteria are for diagnosis. METHODS: Data from 81 cases of @entity4789 were retrospectively collected. INCLUSION CRITERIA: 5 to 15 years of age and diagnosis of @entity4789 confirmed by 2 or more rheumatologists, sustained for at least 6 months and two or more visits. RESULTS: @entity1 had more @entity4790 (23/50.0% vs. 5/14.3%)(p< 0.0001). Cardiovascular (65/80.2%) and joint involvements (63 / 77.8%) were the most frequent manifestations. Fever was noted in roughly half of the @entity1 . @entity625 was more frequent than @entity4841 (47/58.0% vs. 16/19.8%, respectively) (p< 0.0001); however, no specific @entity2720 was found to be more prevalent. @entity339 was the most frequently detected echocardiographic sign (53 / 93.0%) and its association with @entity337 was noted in 27 / 47.4% @entity1 . Only 24 / 29.6% @entity1 fulfilled Jones criteria for @entity4789 requiring an evidence of previous group-A @entity883 (GASI). When compulsory GASI was disregarded, this number rose to 71/87.7% @entity1 (p< 0.0001). CONCLUSION: @entity1 were more affected by @entity4790 ; heart valves and joints were equally affected and represented the major clinical features; no specific @entity2720 (eg.: @entity625 ) could be labeled as typical; and strict adherence to Jones criteria, with compulsory documentation of a previous GASI, may lead to underdiagnosis of @entity4789 .
