Case series of pediatric XXXX : comparison with other Indian series.

@entity1 @entity625 @entity882 @entity1252 @entity1988 @entity4841 @entity3039 @entity221
AIM: To determine the clinical and laboratory characteristics of @entity1 diagnosed with pediatric @entity1252 (pSLE) in the general pediatrics department of a tertiary level hospital in southern India and compare them to data of case series from other parts of the country. METHODS: Retrospective chart review by two independent reviewers. All @entity1 diagnosed with @entity1252 in the pediatrics department of the Amrita Institute of Medical Sciences hospital between 1 January 2004 and 31 September 2008, were included in the study. RESULTS: Twenty @entity1 were diagnosed with pSLE in the above-mentioned period (female : male ratio 2.3 : 1.0). @entity221 (75% of @entity1 ) and @entity4841 (65%) were the most common clinical presenting features. Many @entity1 who were referred as ' @entity221 of unknown origin' (37.5%) or ' @entity3039 ' (15%) fulfilled the diagnosis of @entity1252 on detailed evaluation. Renal manifestations were present in 11 @entity1 , seven of whom underwent a biopsy. Class IV @entity1988 was the most common finding (4/7). A very high percentage of our @entity1 had hypocomplementemia (85%). The statistical significance of the differences between our cohort and previously reported cohorts could not be determined. CONCLUSIONS: pSLE @entity1 in our series, compared to previous literature from India had a much higher incidence of @entity221 , @entity882 and hypocomplementemia at presentation and much lower incidence of @entity625 . It is unclear whether these differences represent unique characteristics of ethnically dissimilar subsets of the Indian population. A high index of suspicion should be maintained in order to make an early diagnosis of pSLE, since the most common presenting features in our cohort were @entity4841 and @entity221 .
