Solid XXXX suggesting malignant potential.

@entity5 @entity1 @entity3
OBJECTIVES: It has been suggested that the histopathologic features associated with malignant potential in solid @entity5 (SPTs) of the pancreas include cellular polymorphism, mitotic activity, peripancreatic tissue invasion, neural invasion, @entity3 , and lymph node @entity3 . This study aimed to delineate the features predicting SPTs with malignant potential, which can be easily assessed in the clinical setting, and long-term results of @entity1 who underwent resection of SPT. METHODS: A retrospective review and analysis were done of 33 @entity1 who had SPTs that were surgically treated. RESULTS: Eleven @entity1 (33.3%) had SPTs suggesting malignant potential among surgically treated @entity1 with SPTs. The local invasion to the peripancreatic tissue was the most frequent malignant pathological feature (7/11 @entity1 , 63.7%). Using univariate analysis, @entity5 size greater than 5 cm was a significant clinical factor to predict SPTs with malignant potential (P = 0.022). The prognosis was excellent. No statistically significant survival difference was noted between groups of malignant potential and benign pathology (P = 0.1904). CONCLUSIONS: Malignant SPTs are low-grade @entity5 with good prognosis. Adequate surgical intervention is necessary. Especially, SPTs over 5 cm in diameter need to be treated carefully because of the chance of malignant pathology. Careful long-term follow-up is necessary in those @entity1 in case of possible @entity5 recurrences.
