[Clinical features of XXXX A H1N1 2009: a multicentre study].

@entity1 @entity121 @entity55 @entity75 @entity16 @entity1395 @entity683 @entity2401 @entity1576 @entity5143 @entity221
OBJECTIVE: To describe clinical and epidemiological features of @entity683 A H1N1 2009 diagnosed @entity1 in the Emergency Department of 4 hospitals. MATERIAL AND METHODS: Prospective multicentre study conducted from july to december 2009. The @entity1 diagnosed by Real-Time PCR of @entity683 A H1N1 2009 in the emergency department were included. The test was requested according to the protocols established throughout the epidemic. Epidemiological, clinical, laboratory variables and outcomes were evaluated. RESULTS: A total of 456 cases were included, with a median age of 6.5years (PC(25-75) 3-10.6). There were risk factors of complications In 266 @entity1 (59.4%) due to the @entity683 , mainly: respiratory (47%), cardiovascular (17%), neurological (14%) and immunosuppression (11%). The most frequent symptoms were @entity221 (96%), (88%) cough, (72%) rhinorrhoea, @entity121 or @entity1395 and breathing difficulties and, less common, @entity16 . Chest X-ray was performed on 224 cases (49%), with lobar (31%) and interstitial (15%) infiltrates. One hundred and forty @entity1 (31%) were hospitalised and 3.2% required Intensive Care Unit (median stay 4 and 3.5days, respectively). The most frequent complications were @entity55 and @entity5143 . Three @entity1 died (a previously healthy @entity1 with @entity2401 and 2 @entity1 with @entity75 due to @entity1576 ). Another case of @entity2401 recovered with sequelae. CONCLUSIONS: The profile of @entity1 with @entity683 A 2009 diagnosed in the emergency department was a school @entity1 , with risk factors of complications, presenting with respiratory symptoms and @entity221 over a short time, and who can be discharged. It is important to emphasise @entity2401 , as well as the usual respiratory complications of @entity683 virus.
