The effect of hyperbaric oxygenation on postradiation XXXX and saliva in @entity1 with @entity135 .

@entity6586 @entity1 @entity135 @entity2133 @entity26 @entity5132
The study was designed to evaluate the influence of hyperbaric oxygenation (HBO) therapy on salivary gland function and the growth of salivary @entity6586 , Lactobacillus and @entity5132 in @entity1 with @entity135 who had undergone radiation therapy. Sixteen @entity1 were included, with radiation doses from 58 to 70 Gy. The first examination was performed at baseline before the first HBO therapy (33.7    9 months after radiation therapy), and the second after 20 daily HBO therapies in a hyperbaric chamber at 2.5 ATA (absolute atmospheres), where @entity1 breathed 100% @entity26 for 90 min each day. Measurements of salivary flow, buffer capacity, saliva pH and colony density of @entity6586 , Lactobacillus and @entity5132 in stimulated saliva were conducted, and @entity2133 grade was assessed. Salivary flow increased from 0.20    0.1 to 0.39    0.2 ml/min at the end of HBO therapy (p < 0.001). Salivary pH also increased from 6.0    0.2 to 6.5    0.1 (p < 0.05). The colony density decreased from the time at baseline to the end of HBO therapy for @entity6586 (p < 0.001), Lactobacillus (p < 0.05) and the fungus @entity5132 (p < 0.05). The @entity2133 grade decreased from 2.63    0.2 to 1.94    0.2 after HBO (p < 0.001). There was no significant change in buffer capacity. The increased salivary secretion rate and salivary pH, and decreased @entity6586 and Lactobacillus colony density that were observed after HBO therapy may reduce caries progression in those @entity1 .
