Diagnosis of XXXX using dynamic contrast-enhanced perfusion imaging with a short acquisition time.

@entity1 @entity706 @entity1313 @entity75 @entity5 @entity11 @entity3
This study sought to determine the diagnostic utility of perfusion parameters derived from dynamic contrast-enhanced (DCE) perfusion MRI with a short acquisition time (approximately 3.5  min) in @entity1 with @entity11 , @entity75 , and @entity706 ( @entity706 ). Twenty-six @entity1 with 29 lesions (4 @entity11 , 13 high-grade @entity11 , 7 @entity3 , and 5 @entity706 ) underwent DCE-MRI in a 3  T scanner. A ROI was placed on the hotspot of each @entity5 in maps for volume transfer contrast K (trans) , extravascular extracellular volume V e , and fractional plasma volume V p . We analyzed differences in parameters between @entity5 using the Mann-Whitney U test. We calculated sensitivity and specificity using receiver operating characteristics analysis. Mean K (trans) values of LGG, HGG, @entity3 and @entity706 were 0.034, 0.31, 0.38, 0.44, respectively. Mean Ve values of each @entity5 was 0.036, 0.57, 0.47, 0.96, and mean Vp value of each @entity5 was 0.070, 0.086, 0.26, 0.17, respectively. Compared with other @entity5 types, @entity11 showed lower K (trans) (P   <   0.01, sensitivity   =   88%, specificity   =   100%) and lower V e (P   <   0.01, sensitivity   =   96%, specificity   =   100%). @entity706 showed higher V e (P   <   0.01, sensitivity   =   100%, specificity   =   88%), but the other perfusion parameters overlapped with those of different histology. Kinetic parameters derived from DCE-MRI with short acquisition time provide useful information for the differential diagnosis of @entity1313 .
