[The expression of XXXX in @entity35 lens epithelial cells of @entity273 -induced @entity231 ].

@entity1605 @entity274 @entity231 @entity273 @entity35
OBJECTIVE: To study the expression and role of @entity1605 in @entity35 lens epithelial cells (LECs) of @entity273 ( @entity274 )-induced @entity231 . METHODS: @entity35 lenses were cultured in vitro and @entity231 was induced by 2 mM @entity274 . The lenses were observed under microscope. Simultaneously, photographs and picture analyses were done in order to detect the variation of the opacity. The expression of @entity1605 in @entity35 LECs was detected with immunohistochemical method and compared with a control group. RESULTS: When the lenses were cultured in 2 mM @entity274 for 3 hours (h), the expression of @entity1605 in @entity35 LECs was increased obviously. There was significant difference between @entity274 -induced and the control group (P = 0.006). After 6 h, vesicles appeared at the equator of the lenses. There was a significant difference between the result of picture analysis of @entity274 -induced and control group (P = 0.013). So the expression of @entity1605 in @entity35 LECs of @entity274 -induced @entity231 was increased before @entity231 occurred. After induced with @entity274 for 24 h, the opacity of lenses and the expression of LECs were both increased as compared with that at 6 h (P = 0.000, 0.000). CONCLUSION: @entity274 can enhance the expression of @entity1605 in @entity35 LECs which may play a role in the mechanism of oxidative stress-induced @entity231 .
