Continuous source imaging of scalp ictal rhythms in XXXX .

@entity1 @entity410 @entity1315 @entity302
PURPOSE: We wished to determine whether continuous EEG source imaging can predict the location of @entity410 onset with sublobar accuracy in @entity1315 ( @entity1315 ). METHODS: We retrospectively analyzed the earliest scalp ictal rhythms, recorded with 23- to 27-channel EEG, in 40 @entity1 with intractable @entity1315 . A continuous source analysis technique with multiple fixed dipoles (Focus 1.1) decomposed the EEG into source components representing the activity of major cortical sublobar surfaces. For the temporal lobe, these were basal, anterior tip, anterolateral, and posterolateral cortex. Ictal EEG onset was categorized according to its most prominent and leading source component. All @entity1 underwent intracranial EEG studies before @entity302 surgery, and all had a successful surgical outcome (follow-up >1 year). RESULTS: Most @entity1 with ictal rhythms having a predominant basal source component had hippocampal-onset @entity410 , whereas those with @entity410 with prominent lateral source activity had predominantly temporal neocortical @entity410 origins. @entity410 with a prominent anterior temporal tip source component mostly had onset in entorhinal cortex. @entity410 in some @entity1 had several equally large and nearly synchronous source components. These @entity410 , which could be modeled equally well by a single oblique dipole, had onset predominantly in either entorhinal or lateral temporal cortex. CONCLUSIONS: Multiple fixed dipole analysis of scalp EEG can provide information about the origin of temporal lobe @entity410 that is useful in presurgical planning. In particular, it can reliably distinguish @entity410 of mesial temporal origin from those of lateral temporal origin.
