Post-transplantation Anemia Predicts XXXX and Poor Graft Function in Kidney Transplant Recipients.

@entity1 @entity455 @entity417 @entity1184 @entity1307 @entity65 @entity122
OBJECTIVE: We aimed to investigate whether low post-transplantation-period hemoglobin levels are predictive of @entity65 in terms of left ventricular (LV) @entity1184 and @entity455 and to determine the contributing factors of post-transplantation @entity417 in kidney transplant (KT) recipients. METHODS: One hundred fifty (mean age, 38.9    10.8  y; 113 male) KT recipients with functioning grafts were enrolled in the study. All subjects underwent clinical and laboratory evaluations (24-hour urinary protein loss, complete blood count) and transthoracic echocardiography to assess LV systolic function. Arterial stiffness was measured by means of carotid-femoral pulse-wave velocity ( @entity122 ). Mean hemoglobin levels were analyzed at the 1st, 6th, 12th, and 24th months after transplantation. @entity1 were divided into 2 groups according to presence of @entity417 : @entity1 with @entity417 (group 1; n  = 120) and normal (group 2; n  = 30). RESULTS: @entity122 values (6.8    1.9  m/s vs 6.4    1.1  m/s in groups 1 and 2, respectively; P  = .002) and LV mass index (LVMI; 252.1    93.7  g/m(2) vs 161.2    38.5  g/m(2) groups 1 and 2, respectively; P  = .001) were significantly higher in group 1. Estimated glomerular filtration rate and (64    28.5  m/min vs 77.8    30  m/min in groups 1 and 2, respectively; P  = .001) LV systolic function (57.2    5.8% vs 77.8    30% in groups 1 and 2, respectively; P  < .005) were significantly lower in group 1. In regression analysis, LV systolic function and LVMI were predictors of post-transplantation hemoglobin levels. CONCLUSIONS: Post-transplantation @entity417 contributes to @entity65 by deteriorating LV function and increasing @entity122 and is therefore associated with poor prognosis for graft survival. Early correction of post-transplantation @entity417 , especially with the use of @entity1307 , may be beneficial for both graft and recipient survivals.
