Somatosensory evoked potentials during mild @entity2332 after XXXX .

@entity1 @entity2332 @entity772 @entity1167
OBJECTIVE: In @entity1 who remain in a @entity772 after @entity1167 ( @entity1167 ), the bilateral absence of cortical N20 responses of median nerve somatosensory evoked potentials (SSEP) 24 hours after admission invariably correlates with a poor neurologic outcome. Nowadays, @entity1167 @entity1 are treated with mild @entity2332 , with simultaneously administered sedative drugs, hampering clinical neurologic assessment. We investigated whether SSEP performed during @entity2332 can reliably predict a poor neurologic outcome. METHODS: Between July 2006 and April 2008, this multicenter prospective cohort study included @entity772 @entity1 admitted after @entity1167 and treated with induced mild @entity2332 (32-34 degrees C). SSEP was performed during @entity2332 , and in @entity1 who remained @entity772 after rewarming, a second SSEP was performed. Neurologic outcome was assessed 30 days after admission with the Glasgow Outcome Scale. RESULTS: Seventy-seven consecutive @entity1 were included in 2 hospitals. In 13 @entity1 (17%), the cortical N20 response during @entity2332 was bilaterally absent. In 9 of these 13 @entity1 in whom SSEP could be repeated during normothermia, the N20 response was also absent, yielding a positive predictive value of 1.00 (95% confidence interval [CI] 0.70-1.00). All 13 @entity1 with absent SSEP during @entity2332 had a poor neurologic outcome, yielding a positive predictive value of 1.00 (95% CI 0.77-1.00). CONCLUSIONS: The results of this pilot study show that bilaterally absent cortical N20 responses of median nerve somatosensory evoked potentials performed during mild @entity2332 after resuscitation can predict a poor neurologic outcome. We started a larger multicenter prospective cohort study to confirm these results.
