XXXX as well as evaluation of safety pharmacology of eucalyptus oil-water emulsions.

@entity35 @entity8 @entity137 @entity11896
Essential oil has performed a variety of indirect services used as insect/pest repellent. The present study investigated the acute and subchronic @entity137 of eucalyptus oil @entity11896 ( @entity11896 ). In addition, we conduct safety pharmacology evaluation of @entity11896 to supplement the @entity137 tests and provide a basis for a comprehensive understanding of the @entity137 of @entity11896 . Acute administration of @entity11896 was done as single dose from 2772 mg to 5742 mg of @entity11896 per kg/bodyweight (b.wt.) and subchronic @entity137 study for thirty days was done by daily oral administration of @entity11896 at doses of 396, 792 and 1188 mg/kg b.wt. In SPF SD @entity35 . The acute @entity137 study showed the LD50 of @entity11896 was 3811.5 mg/kg. The subchronic @entity137 study suggested the high-dose and middle-dose @entity11896 slowed down the growth of male @entity35 . The clinical pathology showed the high-dose and middle-dose @entity11896 could cause @entity8 . The safety pharmacology indicated that @entity11896 had no side effects on @entity35 . These results suggest that @entity11896 is a safe veterinary medicine for external use.
