@entity2516 , intraocular pressure, and XXXX in a white population.

@entity1 @entity227 @entity2516 @entity3467 @entity726 @entity2790 @entity1714
OBJECTIVE: To examine the relation of @entity2516 to @entity726 and intraocular pressure (IOP) in a defined white population. DESIGN: Population-based cross-sectional and follow-up study. @entity1 : @entity1 aged 43 to 86 years living in Beaver Dam, Wisconsin (n = 4926). METHODS: All @entity1 received a standardized assessment of refraction, IOP, and @entity726 at baseline (1988-1990), with IOP remeasured 5 years later (1993-1995). Refraction was defined at baseline as follows: @entity1714 as spherical equivalent of -1.00 diopters (D) or less, emmetropia as -0.75 to +0.75 D, and @entity3467 as +1.00 D or more. MAIN OUTCOME MEASURES: Relation of baseline refraction to prevalent @entity726 (defined from IOP, optic disc, and @entity227 ) and incident @entity2790 (defined as IOP more than 21 mmHg at the 5-year examination in eyes with IOP of 21 mmHg or less at baseline). RESULTS: A myopic refraction was correlated with increasing IOP at baseline (P < 0.001). After controlling for age and gender, @entity1 with @entity1714 were 60% more likely to have prevalent @entity726 than those with emmetropia (odds ratio [OR], 1.6; 95% confidence interval [CI], 1.1, 2.3). In contrast, controlling for age, gender, and baseline IOP, @entity1 with @entity3467 were 40% more likely to have incident @entity2790 than those who were emmetropic at baseline (OR, 1.4; 95% CI, 1.0, 2.0). @entity1714 was not related to incident @entity2790 . CONCLUSIONS: In these population-based data, there was a cross-sectional association of @entity1714 with higher IOP and prevalent @entity726 . Similar associations have been found in previous studies. @entity3467 may be associated with 5-year risk of @entity2790 , a finding that needs further investigation.
