Prefronto-cerebellar transcranial direct current stimulation improves @entity25 in euthymic bipolar XXXX : a brief report.

@entity1 @entity162 @entity76 @entity25
Introduction. Sleep problems are common in @entity162 ( @entity162 ) and may persist during the euthymic phase of the disease. The aim of the study was to improve @entity25 of euthymic @entity162 @entity1 through the administration of prefronto-cerebellar transcranial direct current stimulation (tDCS). Methods. 25 euthymic outpatients with a diagnosis of @entity162 Type I or II have been enrolled in the study. tDCS montage was as follows: cathode on the @entity76 the left dorsolateral prefrontal cortex (DLPFC); the intensity of stimulation was set at 2   mA and delivered for 20   min/die for 3 consecutive weeks. The Pittsburgh Sleep Quality Index (PSQI) was used to assess @entity25 at baseline and after the tDCS treatment. Results. PSQI total score and all PSQI subdomains, with the exception of "sleep medication," significantly improved after treatment. Discussion. This is the first study where a positive effect of tDCS on the quality of sleep in euthymic @entity162 @entity1 has been reported. As both prefrontal cortex and cerebellum may play a role in regulating sleep processes, concomitant cathodal (inhibitory) stimulation of cerebellum and anodal (excitatory) stimulation of DLPFC may have the potential to modulate prefrontal-thalamic-cerebellar circuits leading to improvements of @entity25 .
