Penoscrotal extramammary XXXX : a review of 33 cases in a 20-year experience.

@entity1 @entity154 @entity5 @entity189 @entity4261 @entity2631 @entity544 @entity17995
@entity17995 in @entity1 most frequently involves the penoscrotal area. The uncertainty of the outcome and of the relationship to the underlying @entity189 and associated internal @entity5 still exists. From 1982 to 2001, 33 @entity1 with penoscrotal extramammary @entity4261 were treated and followed up. Therapeutic modalities included @entity544 laser ablation (two @entity1 ) and local wide excision (31 @entity1 ). Split-thickness skin graft (22 @entity1 ), @entity2631 (six @entity1 ), and primary closure (three @entity1 ) were utilized to reconstruct the @entity154 after local wide excision. An underlying @entity189 occurred in seven of 33 @entity1 (21.2 percent). The incidence of associated internal @entity5 was 9.1 percent (three of 33 @entity1 ), including one concurrently and two nonconcurrently associated @entity5 . Eight of 33 @entity1 had local recurrence, representing an incidence of 24.2 percent. Three @entity1 (9.1 percent) had distant metastasis and ultimately died of @entity189 . Of these @entity1 , 31 were grouped according to the degrees of involvement: limited to the epidermis (group 1, n = 14), involvement of the adnexal gland and/or hair follicle (group 2, n = 10), and the presence of an underlying @entity189 (group 3, n = 7). Local wide excision with subsequent reconstruction by split-thickness skin graft was favored in this series. @entity1 with an underlying @entity189 or pathological invasion of the dermis (group 2 or 3) had a worse prognosis than @entity1 without. From this study, it is difficult to address the particular relationship between the outcome and the associated internal @entity5 .
