Sex differences in immunohistochemical expression and capillary density in pancreatic solid XXXX .

@entity1 @entity172 @entity788 @entity5473 @entity1420 @entity39 @entity5 @entity2279 @entity2282 @entity16412 @entity14361 @entity528 @entity165
UNASSIGNED: Solid @entity5 (SPN) is a rare and low-grade malignant @entity788 . Solid @entity5 is rare in @entity1 , and most SPN cases are in young @entity1 . This study aimed to investigate sex differences in SPN clinical histopathology including capillary density and expression of immunochemical markers, including @entity16412 . A total of 22 resected @entity5 from @entity788 @entity1 , including 16 @entity1 (73%) and 6 @entity1 (27%), were analyzed histopathologically and immunohistochemically for @entity5473 , b-catenin, @entity172 receptor, @entity1420 receptor, Ki-67, @entity2282 , @entity2279 , and @entity16412 . The median age was 52.5 years in @entity1 and 24 years in @entity1 (P = .046). The median @entity5 size was 22.5 mm in @entity1 and 40 mm in @entity1 (P = .337). In 11 of the 16 @entity1 (69%), but in none of the @entity1 , @entity5 showed complete or incomplete fibrous cap sules (P = .006). @entity165 clefts were observed in @entity5 from 10 @entity1 (63%) but in none from the @entity1 (P = .012). No significant sex differences were noted in @entity5 characteristics, including size, macroscopic @entity528 , @entity39 , @entity14361 , and perineural invasion. The SPNs were weakly positive for @entity16412 , although there was no significant difference between sexes. Capillary density tended to be lower in @entity5 from @entity1 than in those from @entity1 , but not significantly. Thus, except for the fibrous capsule and @entity165 clefts often found in @entity5 and the younger age of the @entity1 , there were no significant sex differences in histopathologic or immunohistochemical features of SPN, despite its markedly higher occurrence in @entity1 .
