[Prevention of XXXX ].

@entity1 @entity2756 @entity66 @entity10217 @entity2177 @entity3397 @entity1215 @entity7135
In Germany, the incidence of @entity7135 is approximately 1/100,000 and has not risen during recent years. Transmission occurs by direct contact with respiratory droplets, mostly from asymptomatic carriers and less frequently from @entity1 with @entity66 . The incubation period can vary from 2-10 days but usually is 3-4 days. Incidence is highest in @entity1 and decreases with age. The mortality from @entity7135 is approximately 10%. In case @entity10217 is clinically suspected antibiotic treatment (in Germany with @entity3397 or a cephalosporin) should not be delayed. @entity1 must be isolated for at least 24 hours after the institution of antibiotic therapy. For early detection of local outbreaks, public health authorities should be quickly informed of suspected cases. @entity1 in close contact should be treated with antimicrobial chemoprophylaxis. In addition to @entity1215 , @entity2177 or @entity2756 can be used for chemoprophylaxis. For control of local outbreaks of serogroup C @entity7135 , the meningococcal vaccine can be used.
