Location of Initial @entity227 in XXXX and Their Modes of Deterioration.

@entity1 @entity725 @entity227 @entity101 @entity548 @entity6 @entity726 @entity11766 @entity1019
Purpose: To describe the location of initial @entity227 ( @entity227 ) in @entity726 , their modes of deterioration, and those factors associated with different modes of deterioration. Methods: @entity1 with @entity725 were categorized into four groups based on three consecutive initial @entity227 : (1) superior @entity1019 ( @entity1019 ), (2) inferior @entity1019 , (3) superior @entity11766 ( @entity11766 ), and (4) inferior @entity11766 . According to the worsening of the VF, four further subgroups were identified: (1) superior central worsening (CW), (2) inferior CW, (3) superior peripheral or nasal worsening (NW), and (4) inferior NW. Systemic and ocular factors were analyzed for each of the subgroups to identify possible associations. Results: One hundred sixty-two eyes of 162 subjects were analyzed. Superior @entity1019 (n = 40) were more frequent in females and associated with @entity548 ( @entity548 ), and were less frequent in @entity1 with systemic @entity101 ( @entity101 ). Inferior @entity1019 (n = 35) showed a significant association with cup shape measure and axial length. Superior @entity11766 (n = 37) were more highly associated with @entity101 and @entity6 . Inferior @entity11766 (n = 50) showed a lower incidence of @entity548 . With binary logistic regression analysis, superior @entity1019 showed a significant association with both @entity101 and @entity548 . With respect to VF worsening, superior CW showed a significant association with @entity101 and @entity6 , whereas superior NW was associated with a high minimum IOP during follow-up, and inferior NW was associated with a high maximum IOP during follow-up. Conclusions: The initial location and subsequent direction of worsening of @entity227 were associated with different systemic and ocular factors.
