Renal involvement in XXXX : results of treatment with combination chemotherapy.

@entity1 @entity8 @entity66 @entity146 @entity262 @entity1011 @entity1893
Nine (5.1%) of 175 @entity1 with advanced disseminated @entity1893 presented with renal involvement and were initially treated with combination chemotherapy alone. These @entity1 were classified as having renal involvement based on histologic and radiographic criteria. Five of the nine @entity1 presented with a serum @entity1011 level greater than 2.5 mg/dL. Four @entity1 achieved a complete remission of all @entity262 . Eight @entity1 had complete resolution of renal involvement. Two @entity1 later had recurrent @entity8 associated with other sites of recurrence. All five @entity1 who presented with an elevated serum @entity1011 level recovered normal renal function; in fact, four @entity1 had normal renal function by the end of the first cycle of therapy. No @entity1 required hemodialysis. Only one @entity1 remains @entity66 at 55 months; five @entity1 have died with disseminated disease; two @entity1 have died without evidence of disease; and one @entity1 was lost to follow-up while in remission. Initial local control of renal involvement including normalization of renal function in diffuse @entity146 can be rapidly achieved by combination chemotherapy alone.
