Late recurrences of XXXX ( @entity5 ) after 5 years of follow-up.

@entity5 @entity1 @entity677 @entity66
In practice, relapses of @entity5 after long time of surgical resection occur. However, few published data are available for duration, intensity and imaging sources of follow-up in radically excised @entity1 with @entity66 . Therefore, every single institution chooses the surveillance schedule according to its experience. The aim of this study was to describe the late recurrences of disease 5 years after the primary @entity5 's excision in a series of @entity1 with recurrent @entity677 from our institution. We retrospectively reviewed 42 @entity1 with "recurrent" @entity677 , collected since 2001. Ten @entity1 were always followed at our institution, and 32 @entity1 came to our attention at the time of recurrence. The analysed series were divided into two groups: @entity1 who developed recurrence before 5 years and @entity1 who developed recurrence 5 years after the primary @entity5 's excision. Among 42 @entity1 , 36 @entity1 developed the recurrence within 5 years of the primary @entity5 excision, whereas 6 @entity1 developed the recurrence 5 years after primary @entity5 excision diagnosed during follow-up or casually for other reasons. All @entity1 had distant recurrence, involving liver and peritoneum, whereas no local relapse was observed. These @entity1 were heterogeneous in primary @entity5 site, risk classification and molecular analysis. Duration of the follow-up for radically excised @entity1 with @entity677 remains still unsettled; however, the integration of every clinical, pathological and molecular parameter is essential to optimize the duration and intensity of the follow-up for each single @entity1 .
