Survival in major XXXX is predicted by early response to Swan-Ganz-guided resuscitation.

@entity1 @entity26 @entity4808 @entity130
BACKGROUND: Two years ago the authors began to use Swan-Ganz catheters to generate more complex hemodynamic data as a better guide to resuscitation of burns. This study uses the information to identify differences between survivors and nonsurvivors. @entity1 AND METHODS: Fifty-three consecutive @entity1 with major burns were treated using Swan-Ganz-generated data. Additional information was collected, including demographics, intake and output, medications, and arterial blood gas (including calculated @entity26 consumption). Statistical analysis incorporated adjustments for autocorrelation. RESULTS: The @entity1 included 38 @entity1 and 15 @entity1 , averaged 43.7 years of age, and had a mean burn size of 40%. Thirteen @entity1 suffered severe @entity130 . Data collected hourly over 3 days were collapsed across 6-hour observation periods. Mean values, when plotted across time, discriminated the 37 survivors from the 16 nonsurvivors. Poor response to resuscitation as evidenced by increased use of colloid fluid and cardiotonic drugs plus failure to maximize @entity26 consumption were associated with nonsurvival. CONCLUSIONS: Unsustained or inadequate response to @entity4808 was associated with nonsurvival.
