Disease-specific Growth Charts of Marfan Syndrome XXXX in Korea.

@entity1 @entity1614 @entity1635
@entity1 with @entity1614 ( @entity1614 ) presents with primary skeletal manifestations such as tall stature, chest wall abnormality, and @entity1635 . These primary skeletal manifestations affect the growth pattern in @entity1614 . Therefore, it is not appropriate to use normal growth charts to evaluate the growth status of @entity1614 . We aimed to develop disease-specific growth charts for @entity1614 @entity1 and to use these growth charts for understanding the growth patterns in @entity1614 and managing of @entity1 with @entity1614 . Anthropometric data were available from 187 males and 152 females with @entity1614 through a retrospective review of medical records. Disease-specific growth charts were generated and 3, 25, 50, 75, and 97 percentiles were calculated using the LMS (refers to   ,  , and   , respectively) smoothing procedure for height and weight. Comparisons between @entity1614 @entity1 and the general population were performed using a one-sample t-test. With regard to the height, the 50th percentile of @entity1614 is above the normative 97th percentile in both genders. With regard to the weight, the 50 percentile of @entity1614 is above the normative 75th percentile in male and between the normative 50th percentile and the 75th percentile in female. The disease-specific growth charts for Korean @entity1 with @entity1614 can be useful for monitoring growth patterns, planning the timing of growth-reductive therapy, predicting adult height and recording responses to growth-reductive therapy.
