[Skin and @entity1576 caused by polyfunctional XXXX ].

@entity1 @entity3408 @entity10461 @entity2490 @entity56 @entity1576 @entity272 @entity30383 @entity7446 @entity1909 @entity110
BACKGROUND: Polyfunctional @entity30383 ( @entity10461 ) hardener is increasingly used in water-based paints and inks as a replacement for organic solvents. @entity56 contact @entity1909 , contact @entity110 , @entity1576 in occupationally exposed @entity1 with @entity56 to @entity10461 are reported. OBJECTIVES: The aim was to study a population of adhesive tape printers for occupational respiratory and @entity272 to @entity10461 hardener. Also 2 cases of @entity7446 in workers exposed to @entity10461 in tanneries are reported. METHODS: A standard series prick and patch tests was carried out on 15 workers with skin symptoms out of 36 adhesive tape printers exposed to @entity10461 . Prick tests with a 1% @entity10461 water solution and patch tests with a dilution series (0.1-0.32-0.5-1%) of @entity10461 in petrolatum were performed. Lung and nasal provocation tests with @entity10461 hardener were also carried out on 4 subjects with skin and respiratory symptoms. RESULTS: Skin sensitivity to @entity10461 prick tests was demonstrated in 8.3% of the exposed population; 22.2% of the exposed workers suffered from @entity3408 due to @entity10461 with positive patch tests for this compound. One case of occupational @entity2490 due to @entity10461 was diagnosed. CONCLUSIONS: @entity10461 is a strong sensitizer and the use of gloves and protective clothing appears to be insufficient to prevent @entity56 . Elimination of @entity10461 from production processes is desirable.
