[A XXXX case of idiopathic membranous glomerulonephritis associated with isolated anti-nuclear antibody detected by urine mass-screening of school @entity1 ].

@entity1 @entity644 @entity1956 @entity10745 @entity1252 @entity854 @entity811 @entity631 @entity617
A 12-year-old @entity1 was referred to our hospital because of persistent @entity811 with @entity644 . He was found to have @entity854 by a school mass-screening and visited a hospital, where a routine examination revealed @entity644 of 190 mg/d/, @entity811 of 2+ and anti-nuclear antibody (ANA) of 1: 320 with a speckled pattern. The other laboratory findings, including anti-DNA antibody were unremarkable. Hypocomplementemia was not seen. Although he had no disabilities and manifestations suggesting @entity1252 , @entity854 persisted. Percutaneous renal biopsy findings demonstrated stage II diffuse @entity631 ( @entity631 ). Neither @entity1956 virus antigens and antibodies nor @entity10745 virus antibody were detected in his sera. Thus, the diagnosis of idiopathic @entity631 was made. Initiation of a 6-month course of alternate-day @entity617 (an initial dosage at 30 mg) combined with an anti-thrombocyte agent resulted in gradual subsidence of the @entity854 and ANA titer. Although pathogenesis of his @entity631 remains speculative, possible activation of autoimmunities, which led to ANA positivity, might be responsible.
