Health-related quality-of-life among survivors of XXXX in the intensive care unit: a systematic review.

@entity810 @entity1 @entity221 @entity283
PURPOSE: To summarize evidence on long-term @entity283 ( @entity283 ) among survivors of @entity810 ( @entity810 ) in the intensive care unit (ICU). METHODS: We performed a comprehensive search of the literature for studies reporting original data describing @entity283 utilizing validated instruments. Search, study selection and data abstraction were performed in duplicate. Study quality was appraised. Due to study heterogeneity, data are primarily summarized qualitatively. RESULTS: Our search yielded 2193 articles of which 18 were selected for detailed analysis. The quality of these 18 studies was generally good. Numerous @entity283 instruments were utilized, and assessment occurred at variable follow-up duration (range 2 months to 14.5 years). @entity283 among @entity810 survivors was reduced when compared to age/sex-matched populations. @entity283 among survivors with and without @entity810 was generally described as similar beyond 6 months. Physical component domains were consistently more impaired than mental component domains. Survivors had considerable limitations in activities of daily living, implying newly acquired disability, with few returning to work. Despite diminished @entity283 , @entity1 ' @entity283 was generally perceived as satisfactory, and the majority would receive similar treatment again, including renal replacement therapy in the ICU, if necessary. CONCLUSIONS: Among survivors of critical @entity221 complicated by @entity810 , @entity283 was impaired when referenced to population norms, but it was not significantly different from that of survivors without @entity810 . Physical limitations and disabilities were more commonly exhibited by @entity810 @entity1 . Importantly, the impaired @entity283 was generally perceived as acceptable to @entity1 , most of whom expressed willingness to undergo similar treatment in the future.
