Genital herpes and XXXX in healthy young adults.

@entity1 @entity778 @entity1956 @entity281 @entity492 @entity99 @entity493
Although case reports of @entity778 ( @entity778 ) causing acute @entity99 in otherwise healthy adults have appeared recently in the literature, a prospective study of the incidence of @entity1956 in the general population hitherto has not been reported. In the present study, serum samples from 124 young adults attending a sexually transmitted disease clinic with either @entity281 (n = 86) or non-herpes sexually transmitted diseases (n = 38) (controls) were analyzed for @entity99 (including @entity492 aminotransferase [AST] and @entity493 aminotransferase [ALT]). Twelve of eighty-six (14%) herpes-infected @entity1 had mildly abnormal liver enzyme tests (less than or equal to twice the upper limit of normal) as opposed to only 1 of 38 controls (2.6%), (P less than .05). All individuals in the herpes- @entity99 group were anicteric, and only two complained of constitutional symptoms (malaise and fatigue). Liver enzyme tests were repeated in nine herpes- @entity99 @entity1 1 week after their genital lesions had resolved, and in six of nine @entity1 the results had returned to within normal limits. Four @entity1 subsequently returned at the onset of a recurrence of their genital herpes. In all four, serum ALT levels were elevated from the previous occasion, and in three of the four levels just exceeded the upper limit of normal. One @entity1 was followed through three recurrences of his genital herpes. In that individual, the extent of @entity99 appeared to correlate with the presence or absence of his genital lesions.(ABSTRACT TRUNCATED AT 250 WORDS)
