Relationship between uterine biopsy score, XXXX and @entity32 .

@entity281 @entity32 @entity1478 @entity7288
OBJECTIVE: Endometrial biopsy score is an accepted marker of uterine health and predicted fertility, and it has been suggested that endometrial alternations are correlated with susceptibility to persistent @entity7288 . The objective of this study was to investigate associations of endometrial biopsy score with: 1) presence of polymorphonuclear cells (PMNs) in the epithelium and stratum compactum in histopathology; 2) presence of PMNs in cytology and 3) presence of @entity281 in microbiology. MATERIALS AND METHODS: The material for examination was collected from 69 mares suspected for subclinical @entity7288 (bred three or more times unsuccessfully in the same breeding season) and from 15 maiden mares. Samples were collected by endometrial biopsy and cytobrush technique. RESULTS: Endometrial alterations (biopsy score IIA, IIB, III) were found in 64 of 82 mares (78%). There was an increase in PMN occurrence for grades IIA, IIB and III. When comparing grades and PMNs infiltration, we observed statistically significant differences between grades I and IIA (p = 0.222) and grades I and IIB (p  =  0.042) in samples collected by endometrial biopsy. Statistically significant differences were found in microbiological examination (biopsy p  =  0.036; cytobrush p  = 0.189), cytological examination (biopsy p  =  0.040; cytobrush p  =  0.079) and PMN infiltration (p=0.042) between mares with biopsy scores I and IIB. Furthermore, the highest percentage of infected mares was in grade IIA and IIB, and we found statistically significant differences between grades I and IIA (p  =  0.043), and grades I and IIB (p  =  0.036) in biopsy samples. We observed a tendency to higher prevalence of @entity1478 in mares with biopsy score IIA, IIB and III than with biopsy score I in samples collected using cytobrush technique. However, there were no statistical significant differences. CONCLUSION: Degenerative endometrial changes can predispose to uterine @entity281 and @entity32 . Our study shows that mares with endometrial score I are less predisposed to @entity281 than mares with category IIA, IIB and III. Endometrial biopsy is a reliable diagnostic tool.
