Obstetric outcomes after treatment of XXXX during pregnancy: systematic review and meta-analysis.

@entity1 @entity2208 @entity2520 @entity600
OBJECTIVE: To examine whether treatment of @entity2520 with scaling and root planing during pregnancy is associated with a reduction in the @entity600 rate. DESIGN: Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES: Cochrane Central Trials Registry, ISI Web of Science, Medline, and reference lists of relevant studies to July 2010; hand searches in key journals. STUDY SELECTION: Randomised controlled trials including pregnant @entity1 with @entity2520 randomised to either treatment with scaling and root planing or no treatment. DATA EXTRACTION: Data were extracted by two independent investigators, and a consensus was reached with the involvement a third. Methodological quality of the studies was assessed with the Cochrane's risk of bias tool, and trials were considered either high or low quality. The primary outcome was @entity600 (<37 weeks). Secondary outcomes were low birthweight @entity1 (<2500 g), @entity2208 , and overall adverse pregnancy outcome ( @entity600 <37 weeks and @entity2208 ). RESULTS: 11 trials (with 6558 @entity1 ) were included. Five trials were considered to be of high methodological quality (low risk of bias), whereas the rest were low quality (high or unclear risk of bias). Results among low and high quality trials were consistently diverse; low quality trials supported a beneficial effect of treatment, and high quality trials provided clear evidence that no such effect exists. Among high quality studies, treatment had no significant effect on the overall rate of @entity600 (odds ratio 1.15, 95% confidence interval 0.95 to 1.40; P=0.15). Furthermore, treatment did not reduce the rate of low birthweight @entity1 (odds ratio 1.07, 0.85 to 1.36; P=0.55), @entity2208 (0.79, 0.51 to 1.22; P=0.28), or overall adverse pregnancy outcome (preterm births <37 weeks and @entity2208 ) (1.09, 0.91 to 1.30; P=0.34). CONCLUSION: Treatment of @entity2520 with scaling and root planing cannot be considered to be an efficient way of reducing the incidence of @entity600 . @entity1 may be advised to have periodical dental examinations during pregnancy to test their dental status and may have treatment for @entity2520 . However, they should be told that such treatment during pregnancy is unlikely to reduce the risk of @entity600 or low birthweight @entity1 .
