Effects of Thymus kotschyanus var. glabrescens Boiss. extract on XXXX -C induced @entity2008 and sister chromatid exchanges in @entity1 lymphocytes.

@entity1 @entity1138 @entity16 @entity1139 @entity2008
In this investigation, clastogenic effects of Thymus kotschyanus var. glabrescens Boiss. extract (TE) and anticlastogenic effects of this extract against @entity1138 ( @entity1139 ) induced @entity16 have been evaluated in @entity1 peripheral blood lymphocytes in vitro. Two series of experiments were conducted. In the first, only 10(-5), 10(-4), 10(-3) and 10(-2) mul ml(-1) concentrations of TE were used for 48 h to detect potential clastogenicity. In the second, @entity1139 (0.38 mug ml(-1)) plus 10(-5), 10(-4), 10(-3) and 10(-2) mul ml(-1) concentrations of TE were used for 48 h to determine anticlastogenic effects. TE did not increase sister chromatid exchanges (SCEs) (except 10(-2) mul ml concentration) and @entity2008 ( @entity2008 ) significantly compared with negative and solvent controls. However, it decreased the frequency of @entity1139 induced @entity2008 . Decreasing was significant at 10(-4), 10(-3) and 10(-2) mul ml(-1) concentrations. On the other hand, TE significantly increased @entity1139 -induced SCEs for all treatment groups compared with positive control.
