Screening for ophthalmic manifestations of XXXX in the United Kingdom.

@entity1 @entity227 @entity66 @entity13654 @entity3458 @entity12978 @entity941 @entity989
There are marked variations in the manifestations of @entity3458 in different populations. The ocular complications of this condition amongst the Afro-Caribbeans living in the United Kingdom have not previously been reported. We present the preliminary results of an ophthalmic screening programme at King's College Hospital, London. One hundred eyes of 50 @entity1 with @entity3458 were assessed. Full ocular examination was performed including fundus @entity941 angiography. We have looked at the haematological and clinical profile of the @entity1 involved as well as the number of days spent in hospital during the year preceding the eye examination. The incidence of @entity989 was found to be significantly higher than grade I in @entity13654 . This concurs with the results of the Jamaican screening and confirms that these @entity1 are at higher risk of @entity227 than those with @entity66 . Our results also agree with the Jamaican experience which suggest that visual morbidity is mostly due to complications of @entity989 ( @entity989 ). However, the findings in @entity1 without proliferative changes are different; in particular, @entity12978 leading to disciforms are an important cause of @entity227 in Jamaica, but were not seen in any of the 98 eyes examined in this study. No correlation was found between the grade of @entity989 and age, sex, systemic complications and various haematological parameters except for the percentage of haemoglobin F, which was significantly higher in @entity1 with grade I (7.6) compared with grade II (4.2) @entity989 (p = 0.0127).
