Higher parity associated with higher risk of death from XXXX .

@entity1 @entity797 @entity356
AIM: To examine the association between parity and @entity356 (the cases are almost all premenopausal @entity1 ) risk in a cohort of young parous @entity1 . METHODS: The study cohort consisted of all @entity1 with a record of a first and singleton childbirth in the Birth Register between 1978 and 1987. We tracked each @entity1 from the time of her first childbirth to December 31, 2008. Their vital status was ascertained by linking records to the computerized mortality database. @entity797 proportional hazard regression models were used to estimate hazard ratios of death from @entity356 associated with parity. RESULTS: There were 1090 @entity356 deaths (85.87% of them were premenopausal) during 33 686 828 @entity1 -years of follow-up. The mortality rate of @entity356 was 3.24 cases per 100,000 @entity1 -years. A trend of increasing risk of @entity356 was seen with increasing parity. The adjusted hazard ratio was 1.24 [confidence interval (95% CI): 1.02-1.50] for @entity1 who had borne two to three @entity1 , and 1.32 (95% CI: 1.01-1.72) for @entity1 with four or more births, when compared with @entity1 who had given birth to only one @entity1 . CONCLUSION: These results suggest that higher parity may increase the risk of death from @entity356 among premenopausal @entity1 .
