Rehabilitation in XXXX with radically treated respiratory cancer: A randomised controlled trial comparing two training modalities.

@entity1 @entity2 @entity34
INTRODUCTION: The evidence on the effectiveness of rehabilitation in @entity2 @entity1 is limited. Whole body vibration (WBV) has been proposed as an alternative to conventional resistance training (CRT). METHODS: We investigated the effect of @entity34 ( @entity34 ) and of two rehabilitation programmes in @entity2 @entity1 . The primary endpoint was a change in 6-min walking distance (6MWD) after rehabilitation. @entity1 were randomised after @entity34 to either CRT, WBVT or standard follow-up (CON). @entity1 were evaluated before, after @entity34 and after 12 weeks of intervention. RESULTS: Of 121 included @entity1 , 70 were randomised to either CON (24), CRT (24) or WBVT (22). After @entity34 , 6MWD decreased with a mean of 38m (95% CI 22-54) and increased with a mean of 95m (95% CI 58-132) in CRT (p<0.0001), 37m (95% CI -1-76) in WBVT (p=0.06) and 1m (95% CI -34-36) in CON (p=0.95), respectively. Surgical treatment, magnitude of decrease in 6MWD by @entity34 and allocation to either CRT or WBVT were prognostic for reaching the minimally clinically important difference of 54m increase in 6MWD after intervention. CONCLUSIONS: @entity34 of @entity2 significantly impairs @entity1 ' exercise capacity. CRT significantly improves and restores functional exercise capacity, whereas WBVT does not fully substitute for CRT.
