Catching Dengue Early: Clinical Features and Laboratory Markers of XXXX .

@entity1 @entity778 @entity66 @entity1910 @entity548 @entity882 @entity4 @entity551 @entity281 @entity1800 @entity158 @entity1011 @entity4841 @entity8768 @entity779 @entity925
BACKGROUND AND OBJECTIVES: @entity779 is one of the most common @entity66 worldwide. Early diagnosis of @entity779 helps in @entity1 triage and timely management of @entity778 .This study was undertaken to note the early clinical features supported by detection of @entity8768 antigen for diagnosis of @entity778 . METHODOLOGY: In this study a total of 100 adult @entity1 presenting with clinical features of @entity281 from January 2012 to December 2012 were studied.The diagnosis was confirmed with @entity8768 rapid diagnostic test (RDT) whose efficacy was later tested with IgM ELISA. RESULTS: In this study young males were predominantly affected. @entity8768 positivity was 68%. The sensitivity of @entity8768 in predicting @entity281 compared to IgM was 92.86% and specificity was 90% with strength of agreement considered to be 'very good' based on Kappa statistics. Clinical features like @entity158 , @entity925 , @entity4841 , @entity1910 and @entity548 manifestations were significantly associated with @entity8768 positivity. Similarly icterus, @entity4 , @entity551 , altered sensorium, @entity882 and raised @entity1011 were significantly more in @entity8768 positive @entity1 . Anomalously, SGOT was more than SGPT, which can help in differentiating @entity778 from other @entity1800 early in the course. CONCLUSION: We conclude that @entity281 , which possesses serious public health problem, can be diagnosed early with the help of clinical features like @entity158 , @entity925 , @entity548 manifestations, @entity882 and anomalously SGOT greater than SGPT that is supported by detection of @entity8768 antigen.
