@entity995 and @entity876 protein expression in sporadic XXXX .

@entity1 @entity5 @entity996 @entity406 @entity876 @entity982 @entity14 @entity995
AIMS: To ascertain if a relationship between @entity995 ( @entity996 ) and @entity876 proteins exists in sporadic @entity14 . METHODS: Fifty consecutive colectomy specimens for @entity14 in @entity1 over the age of 50 and with no family history of @entity5 in the bowel were examined for immunoexpression of @entity996 and @entity876 proteins. These findings were then related to clinicopathological findings. Commercially available monoclonal antibodies to @entity996 and @entity876 were used on @entity406 -fixed, @entity982 -embedded tissue. RESULTS: The most intense @entity996 immunoexpression was detected in well-differentiated, @entity5 . On the other hand, @entity876 expression was most intense in poorly differentiated, @entity5 . No statistically significant associations were noted with immunoexpression and age, gender or site of lesion. CONCLUSIONS: This study indicates that there is an inverse relationship between @entity996 and @entity876 protein expression in a proportion of sporadic @entity14 . Twelve @entity5 which showed low levels of @entity996 showed high levels of @entity876 protein. Similarly, seven @entity5 with high @entity996 levels displayed low @entity876 expression. In terms of immunohistochemical profile, @entity876 -high/ @entity996 -low @entity5 tended to be poorly differentiated and have advanced stage @entity5 .
