Meta-Analysis of Association of Obstructive Sleep Apnea With XXXX .

@entity1 @entity27 @entity726
OBJECTIVES: Previous studies suggested that @entity27 ( @entity27 ) was associated with @entity726 . However, data on this issue are controversial. This study aims to use meta-analysis to determine whether @entity27 is related to @entity726 . MATERIALS AND METHODS: We searched PubMed, Embase, the Cochrane library, the Web of Science, and the Chinese BioMedical Literature Database disk databases up to November 20, 2014 for related literature. The association of @entity27 with @entity726 was assessed by odds ratio (OR) with 95% confidence interval (CI) as the effect size. Then subgroup analysis was performed according to area and @entity726 type. RESULTS: Six primary studies (3 cohort study and 3 case-control studies) were included in this meta-analysis involving 2,288,701 @entity1 . There was a significant association between @entity27 and @entity726 (adjusted-effect summary for case-control studies OR=2.46; 95% CI, 1.32-4.59, P=0.005) (adjusted-effect summary for cohort studies OR=1.43; 95% CI, 1.21-1.69, P=0.000). There was no significant publication bias. CONCLUSION: @entity27 was a risk factor for @entity726 . A large number of studies is needed to explore the mechanisms that link @entity27 with @entity726 .
