Cysticercosis and XXXX in rural Tanzania: a community-based case-control and imaging study.

@entity1 @entity1707 @entity6583 @entity8785 @entity302
OBJECTIVE: To assess the contribution of @entity6583 ( @entity6583 ) to the burden of @entity302 in a rural Tanzanian population. METHODS: We identified adult @entity1 with @entity302 (PWE) in a door-to-door study in an established demographic surveillance site. PWE and community controls were tested for antibodies to @entity8785 , the causative agent of @entity6583 , and all PWE were offered a computed tomography (CT) head scan. Data on household occupancy and sanitation, @entity1707 -keeping and pork consumption were collected from PWE and controls and associations with @entity302 were assessed using chi-square or Fisher's exact tests. RESULTS: Six of 218 PWE had antibodies to @entity8785 (2.8%; 95% CI 0.6-4.9), compared to none of 174 controls (Fisher's exact test, P  =  0.04). Lesions compatible with @entity6583 were seen in eight of 200 CT scans (4.0%; 95% CI 1.3-6.7). A total of 176 PWE had both investigations of whom two had positive serology along with @entity6583 -compatible lesions on CT (1.1%; 95% 0.3-4.0). No associations between @entity302 and any risk factors for @entity6583 were identified. CONCLUSIONS: @entity6583 is present in this population but at a lower prevalence than elsewhere in Tanzania and sub-Saharan Africa. Insights from low-prevalence areas may inform public health interventions designed to reduce the burden of preventable @entity302 .
