[Toward optimization of XXXX management].

@entity1 @entity151 @entity2 @entity4153
@entity4153 represents 20 to 25 % of all @entity2 . It is characterized by his quickly dissemination. Chemotherapy is the comer stone of @entity151 therapy. However, therapeutic approach are depending on @entity1 's performans states and the disease's extension. The role of radiotherapy is established in the treatment of limited disease. However irradiation's modalities are still discussed. Surgery, usually, contraindicated is, actually, possible in early stages (T1T2N0). Recent advances in molecular biology have created new molecular targeted therapies for SCC but the benefits are not still evaluated. In this article, we review briefly classic strategies that have been evaluated in the management of @entity1 with @entity4153 . This review will, also, focus in the main novel cytotoxic drugs and radiotherapy's modalities and for their clinical implication.
