XXXX associated to a @entity2383 .

@entity1 @entity5427 @entity410 @entity4802 @entity4182 @entity146 @entity17427 @entity2438 @entity245 @entity2319 @entity72 @entity2916 @entity2100 @entity880 @entity209 @entity2008 @entity13526 @entity2388 @entity2383
@entity2438 is the prototype of generalized @entity245 or what today are called @entity72 . In most cases it is impossible to detect a specific etiology. It is estimated that a causative diagnosis may be shown in approximately 10-37% of the cases, including, @entity13526 , @entity2916 , @entity2008 such as @entity2100 and 22q13.3 deletion syndrome, @entity5427 , Smith-Magenis, Sotos, @entity17427 , M  bius, Joubert and @entity4802 , Ito's @entity4182 , as well as certain cerebral malformations and several inherited @entity209 . The case of a 3-year old @entity1 is described, who was considered as autistic according to the criteria established by the DSM-IV manual for @entity146 . She showed a delay in psychomotor development since she was 18 months old; she pronounces very few words (10), points to some objects, does not look up and it is hard to establish eye contact with her. She has @entity2319 and therefore, does not respond when called or when she is given orders, she is beginning to walk. She has not @entity410 . Laboratory tests showed an anion gap of 31.6 mEq/L, @entity880 : 2.55: mmol/L, @entity2388 : 0.06 mmol/L, and elevated @entity880 to/ @entity2388 ratio: 42.5. Under optical microscopy a muscular biopsy showed a reduction of the diameter of muscular fibers. The study of energy metabolism showed a partial @entity2383 , which allowed us to conclude that this was a @entity2383 with an autistic clinical spectrum.
