XXXX : analysis of incidence and survival in Sweden over a 30-year period.

@entity5 @entity1 @entity18393 @entity189
BACKGROUND: The aim of the study was to analyze whether there were any changes in incidence and prognosis of @entity189 diagnosed between 1960 and 1989 in Sweden. METHODS: Data of primary hypopharyngeal @entity5 reported to the Swedish @entity5 Registry were collected. The total number of cases was 2012, 1396 @entity1 and 616 @entity1 , and the end of follow-up was December 31, 1992. RESULTS: For @entity1 , a significant decrease in the age-standardized incidence (ASI) was seen, with an average decrease of 2% per year (p < .001), which was most evident in rural counties. The male @entity1 , on the contrary, showed a significant increase of about 1.5% per year (p < .001); the metropolitan areas had an ASI about twice that of more-rural areas. The 2- and 5-year overall survival was poor, only 25% and 13%, respectively. For @entity1 aged <60 years, no difference in survival between the different 10-year periods was seen, but survival for @entity1 of corresponding ages improved significantly (p < .01) during the last decade, to reach a survival similar to that in @entity1 . For @entity1 aged > or = 60 years, no difference in survival between the different periods or between sexes was seen. CONCLUSION: The increased incidence in @entity5 in @entity1 is similar to that observed for oral and @entity5 in many European countries during this period. The disappearance of @entity18393 may explain the decreased incidence among @entity1 . The treatment results in @entity5 are still very poor, and improvements of the therapeutic methods are needed.
