[Analysis of the surgical outcome and prognostic factors for XXXX ].

@entity1 @entity5 @entity201 @entity1535 @entity4960
OBJECTIVE: To assess the therapeutic strategies and prognostic factors which influence on clinical outcome of @entity201 . METHODS: A total of 144 @entity1 with @entity201 underwent operation between January 1990 and December 2005 were analyzed, including 102 males and 42 females with 36- 74-years-old. All @entity1 underwent resection among which 86 cases (59.7%) had an R0 resection (negative histologic margins), 34 cases (23.6%) had an R1 resection (positive histologic margins), 24 cases (16.7%) had an R2 resection. The @entity1535 -Corlette classification of @entity4960 : 28 cases (23.3%) in type I , 49 cases (40.8%) in type II, 10 cases (8.3%) in type III A, 19 cases (15. 8%) in type III B and 14 cases (11.7%) in type IV. The TNM stages of @entity4960 : 19 cases (15.8%) in stage I, 80 cases in stage II (66.7%), 16 cases in stage III (13.3%), 5 cases in stage IV (4.2%). In @entity4960 , there were 41 cases with well differentiated and 79 cases with moderately and poorly differentiated, 62 cases (51.7%) with negative lymph nodes and 58 cases (48.3%) with positive lymph nodes, 42 cases in stage T1 and 78 cases in stage T2-3, 86 cases with negative blood vessel metastasis and 34 cases with positive blood vessel metastasis. RESULTS: The median survival time was 46.8 months after R0 resection, 18.3 months after R1 resection, and 11.2 months after R2 resection. The 1-, 3- and 5-year cumulative survival rates of the @entity1 were 60.2%, 36.1% and 29.4%. Survival rates after resection in @entity1 with negative lymph nodes (n = 62) were significantly longer than that in those with positive lymph nodes (n = 58) (P < 0.01). The T stage system predicted respectability and the likelihood of an R0 resection and correlated with survival (P = 0.030). @entity1 requiring portal vein resection had a worse prognosis than those without vascular resection (P = 0.047) but still survived longer than @entity1 who were unresectable (P < 0.01). CONCLUSIONS: Negative histologic margins, concomitant partial hepatectomy, and well-differentiated @entity5 histology are associated with improved outcome after all @entity201 resections. In @entity1 who underwent an R0 resection, concomitant partial hepatectomy is the only independent predictor of long-term survival.
