[ XXXX . Differential diagnosis of a case].

@entity70861 @entity1 @entity3742 @entity882 @entity1423 @entity16611 @entity74
@entity882 are a heterogeneous group of extremely rare diseases characterized by a reduced number of blood platelets and by bleeding tendency of variable severity. Some of these diseases are exclusive to platelets, while in others the pathology extends to other cell types. Although rare, @entity882 should be considered in the diagnosis. @entity882 have been classified into three groups depending on platelet volume. @entity882 with giant platelets form one of these groups. About fourteen clinical entities of @entity74 have been described. @entity3742 , grey @entity1423 and @entity16611 are the most @entity70861 . @entity16611 is condition characterized by the triad of @entity882 , giant platelets, and pale-blue inclusions in leukocytes. @entity16611 has an autosomal-dominant mode of inheritance. We described clinical and laboratory features of three adult @entity1 from one family with recently diagnosed @entity16611 . Described cases are probably the first observed cases of @entity16611 in the Czech lands.
