Physical activity, sedentary behavior, and health-related quality of life in XXXX survivors in the health professionals follow-up study.

@entity1 @entity263 @entity66 @entity322 @entity1442 @entity1744
PURPOSE: Many @entity263 survivors experience compromised health-related quality of life (HRQOL) as a result of @entity263 . We examined relationships between types and intensities of activity and @entity263 -related HRQOL, overall, and by @entity66 , and treatment characteristics. METHODS: Associations between post-diagnosis activity and sedentary behavior and HRQOL domains ( @entity322 , @entity1744 /hormonal) were prospectively examined in @entity1 diagnosed with non-metastatic @entity263 in the Health Professionals Follow-up Study (n   =   1917) using generalized linear models. RESULTS: After adjusting for potential confounders, higher duration of total, non-vigorous, and walking activity was associated with higher vitality/hormonal functioning scores (p-trends, <0.0001). Effects were small (d   =   0.16-0.20) but approached clinical significance for @entity1 in the highest vs. lowest activity categories. Survivors who walked >= 90  min/week at a normal pace, or faster, reported higher hormone/vitality scores (p   =   0.001) than @entity1 walking <90  min at an easy pace. Weightlifting was associated with increased @entity322 (p-trend, 0.02). Total activity was associated with higher hormone/vitality functioning in @entity1 who were >= 5  years post-treatment, had more @entity1442 (Gleason score >= 7), and had >= 1 comorbid condition. No relationships were observed between vigorous activity or sedentary behavior and HRQOL. CONCLUSIONS: Increased duration of non-vigorous activity and walking post-diagnosis was positively associated with better hormone/vitality functioning. Specifically, engaging in >= 5  h of non-vigorous activity or >= 3  h of walking per week may be beneficial. IMPLICATIONS FOR CANCER SURVIVORS: Encouraging @entity1 to engage in non-vigorous activity and walking may be helpful for managing @entity263 .
