Prognostic factors for survival after transarterial chemoembolization combined with microwave ablation for XXXX .

@entity1 @entity96 @entity5 @entity157 @entity7838
AIM: To analyze prognostic factors for survival after transarterial chemoembolization (TACE) combined with microwave ablation (MWA) for @entity157 ( @entity157 ). METHODS: Clinical data of 86 @entity1 who underwent TACE combined with MWA between January 2006 and December 2013 were retrospectively analyzed in this study. Survival curves were detected using log-rank test. Univariate analysis was performed using log-rank test with respect to 13 prognostic factors affecting survival. All statistically significant prognostic factors identified by univariate analysis were entered into a Cox proportion hazards regression model to identify independent predictors of survival. P values were two-sided and P < 0.05 was considered statistically significant. RESULTS: Median follow-up time was 47.6 mo, and median survival time of enrolled @entity1 was 21.5 mo. The 1-, 2-, 3- and 5-year overall survival rates were 72.1%, 44.1%, 31.4% and 13.9%, respectively. @entity5 size(  (2) = 14.999, P = 0.000), @entity96 ( @entity96 ) stage (  (2) = 29.765, P = 0.000), @entity1 -Pugh class (  (2) = 51.820, P = 0.000), portal vein @entity5 thrombus (PVTT) (  (2) = 43.086, P = 0.000), @entity7838 (  (2) = 29.791, P = 0.000), MWA therapy times (  (2) = 12.920, P = 0.002), Eastern Cooperative Oncology Group (ECOG) score (  (2) = 28.660, P = 0.000) and targeted drug usage (  (2) = 10.901, P = 0.001) were found to be significantly associated with overall survival by univariate analysis. Multivariate analysis identified that @entity5 size (95%CI: 1.608-4.962, P = 0.000), @entity96 stage (95%CI: 1.016-2.208, P = 0.020), PVTT (95%CI: 2.062-9.068, P = 0.000), MWA therapy times (95%CI: 0.402-0.745, P = 0.000), ECOG score (95%CI: 1.012-3.053, P = 0.045) and targeted drug usage (95%CI: 1.335-3.143, P = 0.001) were independent prognostic factors associated with overall survival. CONCLUSION: Superior performance status, MWA treatment and targeted drug were favorable factors, and large @entity157 , PVTT and advanced @entity96 stage were risk factors for survival after TACE-MWA for @entity157 .
