Inhibition of Peripheral Nerve Scarring by @entity460 Antagonists, Also Known as XXXX Channel Blockers.

@entity1855 @entity254 @entity128 @entity1897 @entity460 @entity35 @entity1930
UNASSIGNED: The aim of this research was to investigate the impact of @entity460 channel blockers ( @entity1855 ) on the formation of scars in the sciatic nerve @entity254 after @entity1897 . One hundred twenty healthy, male @entity35 were selected and prepared with right @entity1930 for this study. Samples were selected at the fourth and 12th weeks, respectively, after treatment and observations were made on the nerve @entity254 healing and diameter. Image analysis and statistical processing were carried out relating to the results of the study. The diameter of the @entity254 of the treatment group at weeks 4 and 12 was noticeably smaller than the control group (P   <   0.05). In the treatment group at week 4, there were many vesicles observed in the fibroblasts' cytosol and in the control group, the fibroblasts exhibited high number of rough endoplasmic reticulum. The collagen content of the nerve scarring at week 12 in the treatment group was apparently less than the control group (P   <   0.01). The @entity460 channel blocker ( @entity1855 ) reduced the axon resistance through the @entity254 during nerve regeneration. It can effectively inhibit the formation of scarring from @entity128 . It also provided an excellent microenvironment for the regeneration of nerve fibers.
