Sex- and gender-specific disparities in XXXX risk.

@entity1 @entity137 @entity5 @entity1442 @entity14 @entity694
UNASSIGNED: @entity14 is one of the most common causes of @entity5 morbidity both in @entity1 and in @entity1 . However, females over 65 years old show higher mortality and lower 5-year survival rate of @entity14 compared to their age-matched male counterparts. The objective of this review is to suggest gender-based innovations to improve @entity14 outcomes in females. @entity1 have a higher risk of developing right-sided (proximal) @entity694 than @entity1 , which is associated with more aggressive form of @entity5 compared to left-sided (distal) @entity694 . Despite differences in @entity5 location between @entity1 and @entity1 , most of scientific researchers do not consider sex specificity for study design and interpretation. Also, @entity14 screening guidelines do not distinguish females from male, which may explain the higher frequency of more @entity1442 when @entity5 are first detected and false negative results in colonoscopy in females. Moreover, socio-cultural barriers within females are present to delay screening and diagnosis. Few studies, among studies that included both @entity1 and @entity1 , have reported sex-specific estimates of dietary risk factors which are crucial to establish @entity5 prevention guidelines despite sex- and gender-associated differences in nutrient metabolism and dietary practices. Furthermore, anti- @entity5 drug use for @entity14 treatment can cause @entity137 to the reproductive system, and gender-specific recurrence and survival rates are reported. Therefore, by understanding sex- and gender-related biological and socio-cultural differences in @entity14 risk, gender-specific strategies for screening, treatment and prevention protocols can be established to reduce the mortality and improve the quality of life.
