Clinical picture and laboratorial evaluation in XXXX loxoscelism.

@entity1 @entity417 @entity882 @entity648 @entity5642 @entity810 @entity2142
Loxosceles spiders are found globally, especially in South and North America. In Brazil, approximately 10,000 cases of Loxosceles spp. spider bites are reported annually. Herein we analyzed 81 @entity1 diagnosed as either cutaneous or cutaneous-hemolytic loxoscelism, in a geographical area where most accidents are caused by Loxosceles gaucho, and we report their clinical and laboratory data obtained during week 1 and 2 after the bite. Massive @entity2142 was noticed in only 2 cases, but high serum @entity648 and LDH levels, suggestive of @entity2142 , were noticed in 25 cases on admission. @entity417 was not frequent (14.7%), and reticulocytosis was particularly noticed during week 2 (in 56% of @entity1 ). High D-dimer levels were suggestive of endothelial cell activation and intravascular thrombin generation, but @entity882 was noticed in only 17.6% of @entity1 in week 1. @entity810 ( @entity810 ) only occurred in @entity1 with massive @entity2142 . The definitive diagnosis of overt disseminated @entity5642 (DIC) could not be established on admission. Fever was associated with the presence of @entity2142 (p  =  0.03). Altogether, these findings provide evidence that mild @entity2142 is frequent in loxoscelism and suggest that @entity810 is uncommon, exclusively occurring in @entity1 with massive @entity2142 .
