Passage of @entity230 through XXXX rubber.

@entity230 @entity134 @entity1346
Implant containers made from @entity1346 rubber have shown little or no foreign body reaction. Prolonged implantation appears to be safe. Previous studies have reported that certain dyes and other materials have passed through the @entity1346 rubber capsule walls. This report examines the possibility of @entity230 passing through the walls of implanted @entity1346 rubber containers. The study used 28 ewes during breeding season. An additional 47 similar ewes were left untreated and served as the control group. The 28 ewes received a subcutaneous implant containing @entity230 . Five different silastic implants were used, with the main differences based on implant shape (surface area), size, and wall thickness. Implant containers were also examined for @entity134 passage in saturated saline solutions. Wall thickness affected @entity134 passage in that the thinner walled capsules allowed larger @entity134 amounts to pass through. @entity230 passed through the walls under in vivo conditions for at least 34 days. In saline solutions passage occurred for at least 7 days. After removal of the implants the ewes returned to the normal heat cyclic schedule.
