Regional profile of XXXX in reversible @entity2806 of Mongolian gerbils.

@entity2806 @entity1399 @entity63 @entity8037 @entity7224 @entity4663 @entity528 @entity11667
Reversible @entity2806 was produced in Mongolian gerbils (Meriones unguiculatus) by occluding both common carotid arteries. After 5 min @entity63 brains were recirculated for 8, 24, 48, 72, or 96 h. An additional 6 animals were subjected to 10 min @entity63 and 24 h recirculation. Sham-operated animals served as controls. At the end of the experiments, brains were frozen in situ and cut in a cryostat. Coronal sections, 10 micron thick, were taken for histological staining. In addition, tissue samples (2-4 mg each) were taken from the cortex, lateral caudoputamen, @entity1399 -layer of the hippocampus, and thalamus. @entity4663 ( @entity11667 , @entity8037 , and the precursor @entity7224 ) were measured in these samples using reverse-phase HPLC and fluorescence detection after extraction and precolumn derivatization. Five-minute @entity2806 had no effect on the levels of @entity7224 , @entity11667 , or @entity8037 . However, following recirculation, @entity7224 increased markedly with time, being most pronounced in the @entity1399 -subfield of the hippocampus, less so in the cortex, and even less so in the thalamus. After prolonged recirculation, severe @entity528 could be observed only in regions exhibiting high @entity7224 levels. @entity11667 or @entity8037 did not change during recirculation, except in severely damaged regions: Here, @entity8037 levels were markedly reduced following prolonged recirculation. The post-ischemic increase in @entity7224 is discussed in respect to the known multiple activities of @entity7224 .
