Sequential hypertonic haemodialysis in XXXX .

@entity1 @entity2125 @entity1372 @entity11849 @entity1391 @entity972 @entity65
Sequential hypertonic dialysis (SHD) was studied in two binephrectomized @entity1 over a period of 6 weeks. Each dialysis session comprised four periods of 45 min. The concentration of @entity1372 in the dialysate [ @entity2125 ] during the first period was 190 mmol/l and during the second period 140 mmol/l. The sequence was then repeated. The @entity1372 -free water clearance [C(ONa)] was calculated from the measurements of the ultrafiltrate clearance and of the @entity1372 clearance. Despite the short periods of hypertonic dialysis, C(ONa) was positive, suggesting that water was removed from the intracellular compartment as well as from the extracellular fluid. The transfer of fluid from the intracellular space improved circulatory stability during rapid removal of large volumes of fluid by ultrafiltration. SHD was also associated with increased removal of @entity972 and @entity1391 . Comparison of clinical parameters before and during SHD showed a tendency towards increased @entity1372 balance and the possibility of raised @entity65 . SHD stabilized blood volume during ultrafiltration, encouraging @entity11849 . SHD with this level of @entity2125 is only a study dialysis method.
