Use of Multisequence 3.0T MRI to Detect Severe XXXX and Predict the Outcome.

@entity1 @entity21 @entity131 @entity548
OBJECTIVES: The aim of this study was to evaluate multisequence 3.0T magnetic resonance imaging (MRI) in the detection of severe @entity131 and in predicting the outcome. METHODS: Thirty-five @entity1 with severe @entity131 were prospectively enrolled and multisequence 3.0T MRI was performed 4-8 weeks post injury. Quantitative data were recorded on each sequence. The ability to display the parenchymal lesions was compared with that of 64-slice spiral computed tomography (CT). The clinical and radiological results were correlated with the Glasgow Outcome Scale Extended (GOSE) scores 6 months after injury. RESULTS: 3.0T MRI could display more lesions than CT, especially when the lesion was deeply located. The lesion volumes and @entity21 ( @entity21 ) scores were different between good and poor outcome groups on FLAIR (P < 0.05). The apparent diffusion coefficient (ADC) values of the splenium of the corpus callosum and brain stem were also different (P < 0.05). @entity1 with unfavorable outcome showed a significantly higher volume of @entity548 on susceptibility weighted imaging (SWI) than favorable ones and were generally located more deeply. Logistic regression analysis revealed that the location of @entity548 and the ADC values of the splenium of the corpus callosum were independent risk factors for poor outcome, with an overall predictive accuracy of 91.4%. CONCLUSION: The joint use of conventional and advanced sequences of 3.0T MRI can comprehensively detect the pathological changes occurring after severe @entity131 . @entity548 and non-hemorrhagic DAIs in deep structures strongly suggest poor outcome. Advances in knowledge: This article improves the understanding of advanced MRI sequences in detection of sTBI @entity1 and prediction of prognosis.
