XXXX rhinovirus serotypes in the nasal washes and mucosa of @entity1 with chronic rhinosinusitis.

@entity1 @entity1729 @entity102
BACKGROUND: @entity102 ( @entity102 ) can be aggravated by @entity1729 . We aimed to investigate whether any specific @entity1 rhinovirus (HRV) serotype is more common in the mucosa of @entity102 @entity1 , and to find any defining clinical characteristics, according to the various HRV serotypes. METHODS: A prospective case-control study was conducted to determine HRV serotypes in 111 @entity102 @entity1 and 51 non- @entity102 controls. No @entity1 had a history of upper @entity1729 over a 4-week period. Nasal lavage fluids and turbinate epithelial cells were collected prospectively. When HRV was detected with multiplex polymerase chain reaction (PCR), strains were further characterized by sequencing the VP4/VP2 region of the HRV genome. RESULTS: HRV was detected in 40 @entity102 subjects (36%) and 11 non- @entity102 controls (21%). The overall detection rates of HRV in @entity102 @entity1 were higher than in non- @entity102 controls (p < 0.05). Of the 8 serotypes detected in @entity102 @entity1 , 5 belonged to HRV-A and 3 belonged to HRV-B; HRV-C was not detected. In non- @entity102 controls, only HRV-A was identified, with only 2 serotypes detected (HRV-A13 and HRV-A16). HRV-B and C were not detected. CONCLUSION: The high prevalence of HRV in @entity102 @entity1 was confirmed in our study. However, we were unable to determine whether certain HRV serotypes are more predominant in @entity102 @entity1 than non- @entity102 controls. HRV-A13 was the most common serotype in both @entity102 @entity1 and non- @entity102 controls. We could not find any differences in the clinical characteristics according to the HRV serotypes in @entity102 @entity1 .
