Interstitial cells of Cajal are decreased in XXXX with @entity6675 associated @entity1944 .

@entity1 @entity1944 @entity3313 @entity4628 @entity1518 @entity6675 @entity8302
BACKGROUND: @entity1944 ( @entity1944 ) is poorly understood. Animal experiments suggest that @entity8302 ( @entity8302 ), play an important role. METHODS: @entity1 with @entity6675 ( @entity6675 ) and @entity1944 (time to full feed >42days) were selected. Age matched @entity6675 and control (NEC, @entity4628 , @entity1518 , and @entity3313 ) samples from primary (T1) and secondary (T2) time points underwent standard histopathology and immunohistochemistry for identification of @entity8302 , followed by evaluation of @entity8302 numbers, distribution, morphology, relation to ganglion cells, and myenteric plexus architecture. Groups were compared using parametric and nonparametric tests. MAIN RESULTS: Twelve @entity1 had samples available for histopathological evaluation. @entity1944 @entity1 had a significantly lower total number of ICCs than controls (3 vs. 8, P<0.0029). @entity8302 number at T1 was 2.5 vs. 6 (P=0.0629) and significantly lower at T2. (3.5 vs. 11, P=0.0124). @entity1944 @entity1 did not show a significant increase of @entity8302 from T1 to T2. Controls showed a significant increase of @entity8302 over time (6 vs. 11, P=0.0408). CONCLUSION: Intestinal samples from @entity1 with @entity1944 who underwent stoma formation demonstrated fewer @entity8302 than controls. There was no improvement or cell recovery during the study period. The ability to modulate @entity8302 may have significant implications for the management of @entity1944 .
