Antisecretory therapy with no improvement in functional level in XXXX .

@entity1 @entity195 @entity601 @entity4059
UNASSIGNED: Conclusion @entity4059 ( @entity4059 ) specially processed cereals (SPC) were not shown to significantly improve the functional level in @entity1 with @entity601 . Objectives The aim of this study was to evaluate the effect of @entity4059 -inducing SPC in @entity1 suffering from @entity195 ( @entity601 ). Methods A randomized double-blinded, placebo-controlled cross-over study was conducted. All @entity1 had a 2 months intake of SPC and control cereal with a 2 months washout period in between. The severity of @entity601 was classified according to the American Academy of Otolaryngology-Head and Neck Surgery (AOO-HNS) functional scale, and the frequency of attacks was registered. Results Thirty-two @entity1 completed the study. No carryover effect was found. In both functional level and frequency of attacks no significant effect of SPC was found. Seventeen @entity1 showed improvement in functional level when treated with SPC (mean improvement   =   0.9 points) and 14 when treated with placebo (mean improvements   =   0.7 points). No @entity1 showed worsening in functional level during treatment with SPC, but three showed worsening when treated with placebo. Seventeen @entity1 reported fewer attacks when treated with SPC, and 22 when treated with placebo. Three @entity1 reported more frequent attacks when treated with SPC, and three when treated with placebo. A non-parametric comparison and a parametric analysis supported the findings.
