Relationship between @entity1307 responsiveness, insulin resistance, and XXXX - @entity731 (MIA) syndrome in hemodialysis @entity1 with @entity6 .

@entity1 @entity32 @entity650 @entity3918 @entity6 @entity39 @entity5 @entity1307 @entity731 @entity1851
BACKGROUND: This study aimed to explore the relationship between recombinant @entity1 @entity1307 ( @entity1307 ) responsiveness, insulin resistance, and @entity32 - @entity731 (MIA) syndrome in hemodialysis @entity1 . METHODS: This was an observational cohort study in hemodialysis @entity1 . Adipokines, inflammatory cytokines, and required @entity1307 dosage were measured in @entity6 ( @entity3918 ; n=58) and @entity6 (non- @entity3918 ; n=58) groups over 48 weeks. Furthermore, the @entity1307 responsiveness index (required @entity1307 dosage divided by hemoglobin) was evaluated with or without @entity32 in both groups. RESULTS: The @entity3918 group had significantly higher plasma leptin, @entity650 ( @entity650 ), and high sensitivity @entity1851 (hs-CRP) levels but lower plasma high molecular weight (HMW) adiponectin levels compared to the non- @entity3918 group. Although hemoglobin levels were not significantly different, required @entity1307 dosage was significantly higher in the @entity3918 group than in the non- @entity3918 group, particularly in the presence of @entity32 . The @entity3918 group with @entity32 had significantly higher plasma leptin, @entity650 , and hs-CRP levels but lower plasma HMW adiponectin levels compared to the non- @entity3918 group with @entity32 . There was also a significant association between @entity1307 dosage and homeostasis model assessment for insulin resistance (HOMA-IR), hs-CRP, @entity650 , @entity5 @entity39 factor a, leptin, and HMW adiponectin levels in @entity3918 @entity1 with @entity32 . CONCLUSION: @entity6 @entity1 with @entity32 have a lower response to @entity1307 and a higher resistance to insulin. This fact may explain the poor outcome of these @entity1 and demonstrate the importance of diagnosis and therapeutic management.
