Mitral Valve Geometry Changes in @entity1 with XXXX .

@entity1 @entity339 @entity337
BACKGROUND: Changes in mitral valve geometry in @entity1 with significant @entity337 ( @entity337 ) have not been evaluated. The aim of the present study was to assess the prevalence of significant secondary @entity339 ( @entity339 ; grade  >=   2) and the geometric characteristics of the mitral valve in @entity1 with moderate and severe @entity337 (grade >=  2) undergoing aortic valve and root surgery. METHODS: One-hundred twenty @entity1 (mean age, 54      15  years; 65% @entity1 ) with @entity337 grade >=  2 undergoing aortic valve and root surgery were retrospectively evaluated. The presence of @entity339 grade  >=   2 and geometry of the mitral valve were assessed on preoperative transthoracic echocardiography. Left ventricular (LV) dimensions and mitral valve geometry were compared between @entity1 with @entity339 grade  >=   2 and @entity1 without. RESULTS: @entity339 grade  >=   2 was present in 28 @entity1 (23%). @entity1 with @entity339 grade  >=   2 had higher European System for Cardiac Operative Risk Evaluation II scores and more often used b-blockers and diuretics than their counterparts. @entity1 with @entity339 grade  >=   2 had larger tenting areas (mean, 1.59      0.79 vs 1.25      0.41  cm(2); P  =  .003), larger inter-papillary muscle distances (mean, 28.4      9.5 vs 24.8      5.2  mm; P  =  .014), larger left atria (mean, 40.9      13.7 vs 32.0      12.2  mL/m(2); P  =  .002), and lower LV ejection fractions (mean, 47.3      12.2% vs 54.3    9.3%; P  =  .002) as compared to @entity1 with @entity339 grade  <  2. However, there were no differences in indexed LV volumes. On multivariate logistic regression analysis, LV ejection fraction (odds ratio, 0.94; 95% confidence interval, 0.89-0.99; P  =  .018) and indexed left atrial volume (odds ratio, 1.05; 95% confidence interval, 1.01-1.10; P  =  .019) remained independently associated with @entity339 grade  >=   2 after correcting for tenting area and inter-papillary muscle distance. CONCLUSIONS: Among @entity1 with @entity337 grade >=  2 undergoing aortic valve and root surgery, the prevalence of @entity339 grade  >=   2 was 23%. Lower LV ejection fraction and larger left atrial volume were independently associated with @entity339 grade  >=   2.
