[Effect of xuebijing injection on perioperative @entity3459 function and inflammatory reaction in senile @entity1 receiving XXXX ].

@entity1 @entity650 @entity556 @entity190 @entity3459 @entity572 @entity1851
OBJECTIVE: To observe the effect of xuebijing Injection (XI) on perioperative @entity3459 and inflammatory reaction in senile @entity1 receiving @entity572 ( @entity572 ). METHODS: Totally eighty @entity1 receiving @entity572 at Luoyang Orthopedics Hospital, 65 to 85 years old, were randomly assigned to the control group (40 cases) and the treatment group (40 cases). All @entity1 received routine perioperative therapies. Those in the treatment group received XI (adding 50 mL XI in 100 mL normal saline, 30 min each time). XI was continually injected after @entity572 , twice daily for 3 successive days. Blood samples were harvested on the morning of the 2nd admission day (TO), immediately after operation (T1), on the morning of the 3rd day after operation (T3), and on the morning of the 5th day after operation (T4) to detect prothrombin time (PT), @entity556 time (TT), activated partial thromboplastin time (APTT), levels of FIB and D-dimer (D-D), changes of white blood cell (WBC), neutrophils (N), @entity1851 ( @entity1851 ), erythrocyte sedimentation rate (ESR), and @entity650 . Complications of surgery were compared between the two groups. RESULTS: There was no statistical difference in operation time, intraoperative @entity190 , and blood transfusion between the two groups (P >0.05). Compared with TO in the same group, WBC, N, @entity1851 , ESR, @entity650 , PT, TT, and D-D all increased in the control group at T1-T4 (P < 0.05); APTT increased at T1-T2 (P <0.05); FIB increased at T1-T3 (P <0.05). WBC, N, @entity650 , PT, and D-D all increased in the treatment group at T1-T3 (P <0.05); @entity1851 and ESR increased at T1-T4 (P < 0.05); TT increased at T1-T2 (P <0.05); APTT and FIB increased at T1 (P <0.05). Compared with the control group at the same time period, WBC, N, @entity1851 , and @entity650 all decreased in the treatment group at T1-T4 (P <0.05), ESR decreased at T3-T4 (P <0.05); PT and TT decreased at T1-T3 (P <0.05); FIB and D-D decreased at T2-T4 (P<0.05). The occurrence of each complication was significantly lower in the treatment groups than in the control group. CONCLUSION: XI could improve the perioperative high @entity3459 state of senile @entity572 @entity1 , inhibit inflammatory reactions, and reduce complications.
