Individual components of the Romhilt-Estes left XXXX score differ in their prediction of cardiovascular events: The Atherosclerosis Risk in Communities (ARIC) study.

@entity1 @entity712 @entity64 @entity301 @entity123 @entity65
BACKGROUND: It has been recently reported that the Romhilt-Estes (R-E) score, originally proposed for detection of left @entity123 from the electrocardiogram, is a strong predictor of all-cause mortality. Whether the R-E score is also predictive of @entity65 ( @entity65 ) and whether its individual components differ in their ability to predict different @entity65 outcomes are not well established. METHODS: This analysis includes 13,261 @entity1 from the ARIC study who were free of @entity65 at baseline (1987-1989). Incident @entity65 , @entity301 ( @entity301 ), @entity712 ( @entity712 ), and @entity64 were ascertained by an adjudication committee through December 2010. The R-E left @entity123 score was measured from automatically processed baseline electrocardiogram data. Cox proportional hazard models were used to examine the association between baseline the R-E overall score (overall) and each of its 6 individual components separately, with each of the @entity65 outcomes. RESULTS: During a median follow-up of 21.8 years, 3,579, 2,205, 1,814, and 731 @entity65 , @entity301 , @entity712 , and @entity64 events, respectively, occurred. In multivariable adjusted models, R-E score >= 4 points (compared with 0 points) was associated with increased risk of @entity65 , @entity301 , @entity712 , and @entity64 (hazard ratio [95% CI] 1.66 [1.41-1.96], 1.66 [1.34-2.07], 1.97 [1.60-2.43], and 1.49 [1.07-2.07], respectively). The 6 component of the R-E score varied in their relationship to different @entity65 outcomes. CONCLUSIONS: The R-E score is predictive of @entity65 outcomes. The 6 R-E score components differ in their associations with different @entity65 outcomes, indicating that they may be electrical biomarkers of different physiological events within the myocardium.
