[Syphilis in Montpellier, France, from 2002 to 2011: Survey in a free hospital screening centre for XXXX and in the dermatology unit of a regional public hospital].

@entity1 @entity2954 @entity2953 @entity281 @entity3397 @entity9385 @entity99
BACKGROUND: In a context of resurgent syphilis in France since 2000, we conducted a retrospective study in two different centres in Montpellier, France: the dermatology department of a public hospital and an anonymous and free centre for provision of information, diagnosis and treatment of @entity2953 (CDAG-CIDDIST). @entity1 AND METHODS: All @entity1 with syphilis seen from January 2002 to December 2011 were included with the collaboration of the National Health Institute (InVS) and the Bacteriology Department of the public hospital. Epidemiology, clinical presentation, serological data, and treatment and monitoring data for up to 2 years were recorded. RESULTS: One hundred and seventy-five cases of syphilis were diagnosed: 154 at the CDAG and 21 at the dermatology unit. Ninety-six percent of cases concerned @entity1 with a median age of 36 years. Eighty-two percent of these cases involved @entity1 having sex with @entity1 (MSM). Forty-nine percent of cases were diagnosed in the secondary stage, 22% in the primary stage and 28% in the latent stage. The treatment administered in the majority of cases (73%) was @entity9385 - @entity3397 . The numbers of @entity1 showing incomplete follow-up were equal at both centres, with 31 @entity1 (17.7%) failing to attend the follow-up visit. A decrease of at least 2 dilutions in VDRL score occurred in the year following treatment for 93 of 103 @entity1 (90%). @entity1 managed at the dermatology department were older than their counterparts managed at the CDAG and exhibited more frequent cutaneous eruptions (58% vs. 3%, P<0.0001) but were less frequently bisexual. However, no significant differences were seen concerning sex and associated @entity281 ( @entity99 , @entity2954 , HPV or herpes). DISCUSSION: Syphilis is on the rise, especially in the MSM population. The epidemiological characteristics of our cohort were consistent with those of other Western European countries. Although the reasons for consultation differed between CDAG/CIDDIST and the dermatology department, the two centres are complementary. @entity9385 - @entity3397 was the most commonly used treatment, in accordance with the recommendations. Measures must be introduced to improve @entity1 monitoring without compromising anonymity.
