Diagnosis and management of XXXX .

@entity1 @entity2735 @entity5 @entity2 @entity1442 @entity358 @entity3
The findings in 28 @entity1 with @entity2 are reviewed. Mediastinoscopy and systemic staging were performed to exclude the possibilities that one @entity358 was metastatic from the other or that both represented systemic @entity3 from another @entity5 . Nineteen @entity1 underwent resection of both @entity5 . Median survival was 25 months for four @entity1 with @entity5 (no nodal involvement; different cell types, bronchoscopically separate endobronchial lesions or arising from separate foci of @entity2735 ) and was 27 months for seven @entity1 with possible synchronous @entity5 (no nodal involvement; similar cell types; located in separate lobes). Median survival was 11 months for 16 @entity1 having @entity5 accompanied by a second @entity2 . In the absence of hilar or mediastinal nodal involvement and systemic @entity3 , @entity5 should be considered separate primaries when located in different lobes, even if they have similar histologic features. Prognosis of @entity5 is related to the presence or absence of nodal @entity3 . Pneumonectomy is the operation of choice for synchronous @entity5 . With @entity5 , sequential resection starting with the most @entity1442 is appropriate. Preservation of lung tissue without compromising the @entity5 operation is critical.
