Sonographically guided biopsy and sonographic monitoring in the diagnosis and follow-up of 2 cases of XXXX with hepatic nodules and inconclusive thoracic findings.

@entity1 @entity3329 @entity1143 @entity738 @entity1353 @entity891 @entity134 @entity370
OBJECTIVE: To report 2 cases in which abdominal sonography played a useful role in diagnosing @entity370 with early nodular hepatosplenic manifestations. METHODS: In the first case, an asymptomatic @entity1 with increased liver enzyme values underwent sonography, which showed multiple hypoechoic nodules in the liver and spleen. Computed tomography confirmed the hepatosplenic findings and showed micronodular infiltrates of both lung fields, without hilar and mediastinal @entity3329 . In the second case, in a @entity1 with a cough, @entity1353 , and increased liver enzyme levels, thoracic computed tomography showed right @entity1143 causing partial @entity891 of the lower and middle lobes and mediastinal @entity3329 . RESULTS: Sonography and computed tomography showed multiple nodules of the liver and spleen and @entity3329 . In both cases, bronchoscopy, bronchial and bronchioloalveolar lavages, and transbronchial and mediastinal biopsies had negative results. Sonographically guided biopsy of the hepatic nodules was carried out and @entity738 were detected in the portal areas. After 3 months of @entity134 therapy, liver enzyme values nearly normalized, and sonography showed the disappearance of all abdominal lesions. The first @entity1 underwent control computed tomography, which confirmed the regression of the disease; the second @entity1 refused control computed tomography. CONCLUSIONS: @entity370 can occur with atypical onset, and in selected cases sonography may play a useful role in its diagnosis and follow-up.
