Single-Fraction Radiotherapy for XXXX (+) @entity1071 .

@entity1 @entity1071 @entity784 @entity5823 @entity1909
Objectives. @entity5823 (+) @entity1071 is a rare variant of @entity784 . Sustained complete response following first-line treatments is rare. This retrospective review evaluates the response of refractory or recurrent lesions to palliative radiation therapy. Methods. The records of 6 @entity1 with 12 lesions, treated with radiation therapy, were reviewed. All @entity1 received previous first-line treatments. @entity1 with clinical and pathological evidence of symptomatic @entity5823 (+) @entity1071 , with no history of other @entity784 variants, and with no prior radiation therapy to the index site were included. Results. The median age of @entity1 was 50.5 years (range, 15-83 years). Median size of the treated lesions was 2.5   cm (range, 2-7   cm). Four sites were treated with a single fraction of 750-800   cGy (n = 3) and 8 sites were treated with 4000-4500   cGy in 200-250   cGy fractions (n = 3). Radiation therapy was administered with electrons and bolus. Median follow-up was 113 months (range, 16-147 months). For all sites, there was 100% complete response with acute grade 1-2 @entity1909 . Conclusions. For recurrent and symptomatic radiation-na  ve @entity5823 (+) @entity1071 lesions, palliative radiation therapy shows excellent response. A single fraction of 750-800   cGy is as effective as a multifractionated course and more convenient.
