A new utilization area for hyperbaric XXXX ? Improving quality of stored blood.

@entity1 @entity1792 @entity26 @entity1391 @entity413
BACKGROUND/AIM: Since blood bags have the ability for diffusion of gases, we investigated whether hyperbaric @entity26 (HBO) exposure affects several vital parameters of stored blood. MATERIALS AND METHODS: Bloods obtained from the same @entity1 were used as both control and HBO groups and stored in pediatric bags with @entity1792 - @entity1391 - @entity413 solution. HBO administration was performed at 2.5 atm for 90 min, started 1 day after blood collection and repeated every 2 days for a total of 10 times. The study was terminated on the 21st day. Complete blood count, @entity413 , pH, and osmotic fragility values were measured every week. RESULTS: @entity413 and pH levels decreased in stored blood. In the HBO-exposed group, these decreases were less than in the control. In addition, mean corpuscular and platelet volumes tended to increase during storing process, but with HBO, these indexes remained lower, near physiologic levels. Another interesting finding of the study was the relative stable osmotic fragility ratio in the HBO group compared to the control blood. CONCLUSION: HBO exposure has positive effects on pH, stability of erythrocytes, and energy source ( @entity413 ) of the medium. Thus, we concluded that HBO may be a useful application for life and quality of stored blood.
