Inmunohistochemical detection of mastocytes in tissue from @entity1 with actinic XXXX .

@entity1 @entity1711 @entity10212 @entity1710 @entity982 @entity56 @entity9586
BACKGROUND: Actinic @entity9586 (AP) is a type of photodermatosis, the pathophysiology of which has not been determined. AP has been suggested to be a @entity56 reaction to the presence of eosinophils and the local production of IgE. MATERIAL AND METHODS: Descriptive study, using @entity982 blocks of tissue that have been diagnosed with AP from the Dermopathology department, Hospital General Dr. Manuel Gea Gonz  lez. In 66 blocks from 63 @entity1 , eosinophils were identified by @entity1710 and @entity1711 staining, and mastocytes were labeled by immunohistochemistry. Three random microphotographs (40x) were used, and cell counts were calculated as the mean count in the 3 microphotographs. RESULTS: Forty cases (63.5%) were female, and 23 (36.5%) were male. The mean age was 26.49   14.09 years; regarding the evolution time of the disease, the average was 11.93 years   11.39. In 38 of 63 cases (60%), the lip, skin, and conjunctiva were affected clinically. In 22 of 63 cases (34%), AP @entity10212 was the sole manifestation, and in 4 of 63 cases (6%), there were lesions in the skin and conjunctiva. The mean eosinophil count was 9 per case, the average number of mastocytes/field was 28.48 (range 0 to 66) Kruskal-Wallis p=0.001. CONCLUSIONS: There are elements in AP that mediate the reaction of @entity56 type IV b, necessitating the identification of triggering factors. Key words:Actinic @entity9586 , eosinophil, @entity56 IV b, IgE, mastocytes.
