Evaluating XXXX in Non-Diabetic Uremic @entity1 on Peritoneal Dialysis.

@entity1 @entity4024 @entity1372 @entity2753 @entity177 @entity3147 @entity1381 @entity298
UNASSIGNED:     BACKGROUND: An approach to @entity2753 in @entity1381 @entity1 on @entity298 ( @entity298 ) necessitates the assessment of intracellular fluid volume (ICV) and extracellular volume (ECV). The aim of the study was to evaluate the association of plasma @entity1372 ( @entity4024 ) concentration and body fluid composition and identify the causes of @entity2753 in non-diabetic @entity298 @entity1 .     METHODS: Sixty non-diabetic @entity1381 @entity1 on @entity298 were enrolled. Baseline body fluid composition, biochemistry, hand-grip test, peritoneal membrane characteristics, dialysis adequacy, @entity4024 and water balance, and @entity177 ( @entity177 ) were measured. These parameters were reevaluated for those who developed @entity2753 , defined as serum @entity4024 concentration < 132 mmol/L and a decline in serum @entity4024 > 7 mmol/L, during monthly visits for 1 year. Body fluid composition was determined by multi-frequency bioelectrical impedance (BIA).     RESULTS: There was no significant correlation between serum @entity4024 concentrations and any other parameters except a negative correction with overnight ultrafiltration (UF) amount (p = 0.02). The ICV/ECV ratio was positively correlated with serum albumin (p < 0.005) and hand grip strength (p < 0.05). Over 1 year, 9 @entity1 (M:F = 3:6, aged 35 - 77) with 4 different etiologies of @entity2753 were identified. Hyponatremic @entity1 with a body weight (BW) loss had either an increased ICV/ECV ratio associated with primarily a negative @entity4024 balance (n = 2) or a reduced ratio of ICV/ECV associated with @entity3147 (n = 2). In contrast, hyponatremic @entity1 with a BW gain had either a reduced ICV/ECV ratio associated with a rapid loss of @entity177 and a higher peritoneal permeability (n = 2) or a normal to increased ICV/ECV ratio associated with high water intake (n = 3).     CONCLUSION: Besides BW change and ultrafiltration rate, the assessment of ICV/ECV ratio is valuable in identifying the etiologies of @entity2753 in @entity298 and provides a guide for optimal therapy.
