Craniosacral Therapy for the Treatment of XXXX : A Randomized Sham-controlled Trial.

@entity1 @entity308 @entity4048 @entity148 @entity158
OBJECTIVES: With growing evidence for the effectiveness of craniosacral therapy (CST) for @entity158 management, the efficacy of CST remains unclear. This study therefore aimed at investigating CST in comparison with sham treatment in chronic nonspecific @entity4048 @entity1 . MATERIALS AND METHODS: A total of 54 blinded @entity1 were randomized into either 8 weekly units of CST or light-touch sham treatment. Outcomes were assessed before and after treatment (week 8) and again 3 months later (week 20). The primary outcome was the @entity158 intensity on a visual analog scale at week 8; secondary outcomes included @entity158 on movement, pressure @entity158 sensitivity, functional disability, health-related quality of life, well-being, @entity148 , @entity308 , stress perception, @entity158 acceptance, body awareness, @entity1 ' global impression of improvement, and safety. RESULTS: In comparison with sham, CST @entity1 reported significant and clinically relevant effects on @entity158 intensity at week 8 (-21 mm group difference; 95% confidence interval, -32.6 to -9.4; P=0.001; d=1.02) and at week 20 (-16.8 mm group difference; 95% confidence interval, -27.5 to -6.1; P=0.003; d=0.88). Minimal clinically important differences in @entity158 intensity at week 20 were reported by 78% within the CST group, whereas 48% even had substantial clinical benefit. Significant between-group differences at week 20 were also found for @entity158 on movement, functional disability, physical quality of life, @entity148 and @entity1 ' global improvement. @entity158 sensitivity and body awareness were significantly improved only at week 8. No serious adverse events were reported. DISCUSSION: CST was both specifically effective and safe in reducing @entity4048 intensity and may improve functional disability and the quality of life up to 3 months after intervention.
