[Long-term results of chemotherapy alone or combined with radiation therapy for XXXX ].

@entity5 @entity1
BACKGROUND: To evaluate therapeutic outcome of @entity5 treated with chemotherapy alone or combined with radiation therapy with different doses. METHODS: A retrospective analysis was performed in 128 @entity5 @entity1 who were treated with three different ways of treatment, from February 1988 to March 1998 in @entity5 Hospital. All @entity1 were pathologically proved. Forty-two @entity1 received chemotherapy alone (C), 48 @entity1 were treated by interdigitating chemoradiotherapy (IDG) and other 38 @entity1 received concurrent chemoradiotherapy (CON). For thoracic radiation, 20 @entity1 received a dose of  <=45 Gy, 23 >= 60 Gy, and 43 > 45 Gy but < 60 Gy . RESULTS: The 3-year survival rates were 23.7%, 20.8% and 4.8% in the CON, the IDG and the C groups respectively. There was a significant difference between the CON and the C groups ( P < 0.05), as well as between the IDG and the C groups ( P < 0.05). There was no remarkable difference between the CON and the IDG groups ( P > 0.05). Loco-regional recurrence rate was significantly higher in  <=45 Gy group (55.0%) than that in >= 60 Gy group (8.7%)( P < 0.01). CONCLUSIONS: The chemotherapy combined radiotherapy may improve the survival of @entity1 with @entity5 . Dose of thoracic radiation might be related to the loco-regional recurrence.
