Early detection of silent ischemia and @entity67 in asymptomatic young @entity101 XXXX .

@entity1004 @entity1 @entity101 @entity731 @entity741 @entity453 @entity67
BACKGROUND: There is an association between @entity453 ( @entity453 ) and increased @entity1004 ( @entity1004 ), a surrogate index of @entity731 . This association is poorly studied in asymptomatic subjects with risk factors of @entity453 . AIM: To study the relationship between carotid- @entity1004 , coronary flow reserve (CFR) and cardiac function in asymptomatic young @entity101 subjects. METHODS: This study includes 82 asymptomatic young subjects with essential @entity101 , and 78 healthy control subjects. Carotid- @entity1004 was assessed with B-mode ultrasonography. Treadmill exercise test, CFR and echo Doppler study were performed for all subjects. RESULTS: @entity101 group had a significantly higher carotid- @entity1004 (0.91 + 0.13 vs. 51    0.09, P < 0.01), and a significantly lower coronary flow velocity reserve (1.9    0.44 vs. 3.2    0.44, P < 0.003) than in control subjects, especially in those with stress induced @entity741 . Multiple linear regression analyses shows that increased carotid- @entity1004 was related to a reduced CFR (r = -843, P < 0.001) and a lower diastolic function (E/e   , r = -512, P < 0.003) in asymptomatic @entity101 . In addition the carotid- @entity1004 showed a significant correlation with family history of @entity101 in these subjects (r = 653, P < 0.002). CONCLUSION: Carotid- @entity1004 increases significantly in asymptomatic young @entity101 @entity1 . It has a relationship with stress-induced @entity741 , decrease CFR and incipient @entity67 in those @entity1 . It could be considered as an index for subclinical @entity731 and @entity67 in asymptomatic subjects with risk factors for CADs.
