XXXX of the ethmoid: Outcomes of a treatment regimen based on endoscopic surgery with or without radiotherapy.

@entity1 @entity420
BACKGROUND: The purpose of this study was to assess survival, prognostic factors, and complications in a cohort of @entity1 with @entity420 ( @entity420 ) treated with transnasal endoscopic surgery        radiotherapy (RT). METHODS: @entity1 with @entity420 who underwent endoscopic surgery        RT at 2 tertiary centers were retrospectively reviewed. Overall survival (OS) and event-free survival were calculated, and statistically significant variables were entered in a multivariate Cox regression model. Complications were also analyzed. RESULTS: One hundred-sixty-nine @entity1 were included. Major complications occurred in 9.5% of @entity1 . Adjuvant RT was delivered in 58.6% of @entity1 . Five-year OS and event-free survival were 68.9% and 63.6%, respectively. Advanced pT classification, high-grade, and positive surgical margins were independently predictive of poor survival. CONCLUSION: Endoscopic surgery        RT is a valid treatment option in most cases of @entity420 . When compared with series based on external surgery, our results support a definitive paradigm shift in the management of @entity420 .    2015 Wiley Periodicals, Inc. Head Neck 38: E996-E1003, 2016.
