Prospective randomized study of XXXX in the management of premature rupture of the membranes and the premature gestation.

@entity1 @entity7288 @entity5935 @entity649 @entity5870 @entity281 @entity1442 @entity204 @entity4291 @entity288
A prospective randomized study involving @entity1 with premature rupture of the membranes between the twenty-eighth week and the thirty-fourth week of pregnancy was conducted. @entity1 with @entity5870 , @entity1442 , and fetal distress, as well as those with mature lecithin/ @entity4291 ratios and/or Gram stains positive for bacteria, were delivered immediately. The remaining @entity1 were randomized. One group received @entity5935 . Tocolytic agents were used in this group when necessary. After 48 hours all @entity1 given @entity288 (CS group) were delivered). The second group was managed expectantly (EM group) and were delivered only when spontaneous labor or @entity281 occurred. A total of 160 @entity1 were randomized, 80 in each group. Maternal outcome, including @entity5870 and cesarean section rates, was not different; however, the @entity7288 rate was significantly higher in the CS group (p less than 0.05). Neonatal outcome did not differ in mean birth weights, perinatal @entity204 rates, @entity281 , or incidences of @entity649 . The frequency of prolonged hospital stay (greater than 4 weeks) was higher in the neonates in the CS group (p less than 0.01). The conclusion is that @entity288 and active management in @entity1 with premature rupture of the membranes and premature gestations do not decrease the incidence of @entity649 or perinatal mortality and may aggravate certain infectious complications.
