C cell XXXX : a rare but distinct clinical entity.

@entity1 @entity175 @entity527 @entity5 @entity189 @entity787 @entity730 @entity3508 @entity652 @entity259
Although the benign counterpart of @entity189 of the thyroid has never been indicated in textbooks, we propose that C cell @entity652 is a rare but distinct clinical entity. Two @entity1 , a 43-year-old @entity1 and a 53-year-old @entity1 , had similar @entity259 , both about 4 cm in diameter. The cut surfaces of the resected @entity5 were indistinguishable from a common microfollicular @entity259 . Microscopically, the @entity5 were uniformly composed of fusiform cells without any follicle formation. Neither @entity527 nor @entity730 was found. Although some kind of C cell @entity5 were suggested, the exact nature was debatable. However, extremely high levels of @entity175 (1330 and 2065 pg/ml, respectively; normal level, less than 170 pg/ml) were found in the stored sera taken preoperatively. Serum levels of @entity787 ( @entity787 ) were normal in both @entity1 . Immunohistochemically, the @entity5 tissues were positive for @entity175 and @entity3508 but negative for @entity787 with a monoclonal anti- @entity787 antibody. No somatostatin, glucagon, or adrenocorticotropic hormone activity was found. It is highly probable that such @entity5 have not been closely studied and have been regarded as eccentric adenomas of the thyroid or simply as the so-called @entity189 of the thyroid.
