Acral calcified @entity11003 of the skin: a rare clinicopathological variant of cutaneous XXXX : report of 3 cases.

@entity1 @entity8 @entity11003 @entity5 @entity11708 @entity730 @entity2909
BACKGROUND: Several histopathologic variants of cutaneous @entity2909 have been recognized. In our consultation dermatopathology practice, we encountered a variant of @entity11708 which, to our knowledge, has not been reported. OBJECTIVE: We report 3 cases of @entity11003 , all of them manifesting prominent intratumoral @entity730 dominating over the residuum of the @entity5 and occurring on the acral sites. METHODS: We conducted a clinicopathological and immunohistochemical study, which is complemented by a literature review. RESULTS: All 3 @entity1 were @entity1 ranging in age from 57 to 72 years. Each presented clinically with a slowly growing, firm mass. The lesion was painful in two cases. None of the @entity1 had @entity8 . Microscopically, the lesions were a well-circumscribed, @entity5 composed of mature smooth muscle cells and vascular pattern, which was inconspicuous, but focally dilated blood vessels were present. In all cases, prominent @entity730 were present. Immunohistochemically the spindle cells were positive for alpha-smooth muscle actin. LIMITATIONS: This study utilizes tissue specimens that all came as consultations; therefore, some inherent selection bias exists. CONCLUSION: Acral calcified @entity11003 is a rare clinicopathological variant of @entity2909 which has predilection for acral sites and shows massive @entity730 prevailing over the @entity5 itself.
