[237-POS]: XXXX - A late presentation to keep in mind.

@entity1 @entity644 @entity410 @entity227 @entity101 @entity3036 @entity1468 @entity10 @entity16757
OBJECTIVES: Presentation of two cases of late postpartum @entity3036 that took place at our hospital, one month apart. Eclampsia is defined as generalized @entity410 , in the setting of @entity1468 , without other neurologic conditions. With an incidence of 1:2.000 deliveries in developed countries, it occurs in 2% of @entity1 with severe @entity1468 and in 0.5% of those with non-severe @entity1468 . Although it may occur from gestation to puerperium, it is estimated that only 5-17% of cases take place after 48h postpartum. @entity3036 is a clinical diagnosis, most cases present with @entity16757 ( @entity16757 ) findings on MRI. METHODS: Review of literature and consultation of clinical files. RESULTS: CASE 1 - A 28-year-old female, G2P0, underwent cesarean delivery, at 38 weeks' gestation, in the setting of @entity1468 and abnormal nonstress test. On day 6 postpartum, she experienced @entity10 , after which she had three generalized @entity410 . On admission, she was postictal and @entity101 (170/120mmHg), @entity644 4+, normal CT scan and EEG. MRI revealed lesions compatible with PRLS. She was admitted to the ICU and treated with magnesium sulfate, valproate and antihypertensive medication, with no further @entity410 and gradual normalization of blood pressure. CASE 2 - A 31-year-old female, G5P3, with gestational @entity101 , underwent vaginal delivery at 40 weeks' gestation. Since day 2 postpartum she complained of a mild @entity10 . On day 4 she developed @entity227 followed by generalized tonic-clonic @entity410 . At admission to the ICU, BP was 168/110 mmHg. CT and EEG were normal. MRI revealed @entity16757 . She underwent therapy with magnesium sulfate, valproate and antihypertensive therapy, with no additional @entity410 and stabilization of blood pressure. CONCLUSIONS: Prompt exclusion of other causes of @entity410 , especially in late presentations, combined with early diagnosis and treatment, are central to avoid morbidity and mortality associated with @entity3036 . DISCLOSURES: S. Nascimento: None. R. Gomes: None. T. Matos: None. I. Santos: None. F. Matos: None.
