Sleep duration is significantly associated with carotid artery XXXX incidence in a Japanese population.

@entity1 @entity1004 @entity167 @entity731 @entity413 @entity4288
BACKGROUND: Previous studies have indicated that sleep duration is associated with total mortality in a U-shaped fashion. The purpose of the current study was to examine the relationship between self-reported sleep duration and carotid artery @entity731 in a Japanese population. METHODS: In 2009-2010, a total of 2498 @entity1 (1195 @entity1 , 1303 @entity1 ; age range, 23-92 years) were recruited from members of a Japanese community receiving annual health check-up at a local health center who agreed to participate in the study. Exclusion criteria were as follows: age <40 or >= 85 years; and more than one missing value from either laboratory data or questionnaire responses. A total of 2214 @entity1 were entered into the study. Carotid @entity4288 was evaluated ultrasonographically and quantified as @entity1004 ( @entity1004 ). The presence of carotid artery @entity731 was defined as @entity1004 >= 1.2 mm. Sleep durations were compared with @entity1004 measurements after controlling for confounding factors such as age, sex, lipid profile, fasting plasma @entity413 , hemoglobin A1c, blood pressure, @entity167 intake, and smoking habit. RESULTS: Sleep duration >= 7 h correlated significantly with the incidence of @entity1004 >= 1.2 m when compared with a sleep duration of 6 h (multivariate-adjusted odds ratio, 1.263; 95% confidence interval, 1.031-1.546, P=0.024). Shorter sleep duration  <=5 h did not correlate significantly with the risk compared with a sleep duration of 6 h. CONCLUSION: Long sleep duration (>= 7 h) correlated significantly with the incidence of carotid artery @entity731 compared with a sleep duration of 6 h, but shorter sleep duration did not.
