Early Cardiovascular Disease After the Diagnosis of XXXX .

@entity1 @entity583 @entity64 @entity785
PURPOSE: The purpose of this study is to assess risk and time trends of newly recorded @entity583 and @entity64 in cases with @entity785 . METHODS: We conducted a matched incident cohort study (1996-2010) among @entity1 satisfying at least one of the following: 1) diagnosis of @entity785 on at least 2 visits within a 2-year period by a nonrheumatologist physician; or 2) diagnosis of @entity785 on at least one visit by a rheumatologist or from hospitalization; as well as receiving no prior @entity785 diagnosis between 1990 and 1995. Ten controls were matched by birth year, sex, and calendar year of exposure from the general population for each case. Incident @entity583 , @entity64 , and @entity583 or @entity64 was recorded from hospital or death certificates. We estimated incidence rate ratios and hazard ratios (HRs) after adjusting for confounders. RESULTS: Among 1239 individuals with @entity785 and no history of @entity583 (83% female, 56 years old), the incidence rate for @entity583 was 13.0/1000 @entity1 -years vs 4.1/1000 @entity1 -years in the comparison cohort. The incidence rate for @entity64 was 8.0/1000 @entity1 -years vs 3.7/1000 among controls. The adjusted HRs were 3.49 (95% confidence interval [CI], 2.52-4.83) and 2.35 (95% CI, 1.59-3.48) for @entity583 and @entity64 , respectively. For @entity583 and @entity64 , the risk was highest within the first year following diagnosis (HR 8.95; 95% CI, 5.43-14.74 and HR 5.25; 95% CI, 2.90-9.53, respectively). CONCLUSION: This large general population-based study indicates an increased risk of @entity583 and @entity64 in @entity1 with @entity785 , especially within the first year of diagnosis.
