Detection and significance of parametrial micrometastases in XXXX .

@entity1 @entity3944 @entity5 @entity66
BACKGROUND: Parametrial metastases are rare in @entity1 with small, node-negative cervical @entity5 . We examined the incidence of micrometastases in @entity1 with pathologically negative parametria. @entity1 AND METHODS: @entity1 with @entity5 who underwent radical hysterectomy and had no evidence of parametrial metastases were examined. Immunohistochemistry (IHC) using a cytokeratin antibody was performed in parametrial sections. RESULTS: Among 46 @entity1 , a parametrial micrometastasis was identified in 1 (2.2%). @entity3944 were seen in 5% of @entity1 with lymphvascular space invasion (LVSI) and in 0 (0%) @entity1 without LVSI (p=0.43). The @entity1 with a parametrial micrometastasis experienced recurrence and died from her disease. In a previous report, we defined @entity1 with @entity5 <2 cm, negative pelvic lymph nodes, and no LVSI as being at low-risk for @entity66 . There were no micrometastases in this group of @entity1 in the current series. CONCLUSION: Parametrial micrometastases are uncommon in @entity5 .
