Prognostic value of DNA ploidy patterns of XXXX .

@entity5 @entity1 @entity14
BACKGROUND/AIMS: The significance of prognostic value of DNA ploidy patterns of @entity14 has not yet been fully understood. The present study was designed to determine the prognostic value of DNA ploidy patterns for @entity14 after resection. METHODOLOGY: We have prospectively collected @entity5 specimens from 420 @entity1 with @entity14 since 1996. The DNA ploidy patterns were determined with the use of DNA flow cytometry. The correlation of DNA ploidy pattern and various characteristics of @entity5 and the prognostic significance of DNA ploidy patterns were evaluated by univariate as well as Cox's proportional hazard model. The disease-free survival curves were calculated with Kaplan-Meier's analysis, and the survival difference was determined by log-rank test. RESULTS: DNA ploidy patterns were diploid in 115 (27.4%) and aneuploid in 305 @entity1 (72.6%). The pattern of DNA ploidy did not correlate with age, gender, location, differentiation, and stage of the @entity5 . In 146 @entity1 who were followed up for at least 2 years, the disease-free survival curves were similar between the diploid and aneuploid group. Multivariate analysis disclosed that @entity5 staging was associated with the survival of @entity1 but the DNA ploidy pattern had no prognostic significance. CONCLUSIONS: The DNA ploidy pattern was not a significant prognostic factor in short-term follow-up.
