Amygdala volumetry in "imaging-negative" XXXX .

@entity1 @entity131 @entity410 @entity851 @entity75 @entity1283 @entity5 @entity854 @entity1315 @entity302 @entity717
OBJECTIVE: Although @entity854 are sometimes suspected in "imaging-negative" @entity1 with video EEG confirmed unilateral focal @entity302 suggestive of @entity1315 ( @entity1315 ), amygdala asymmetry is difficult to assess visually. This study examined a group of "imaging-negative" @entity1315 @entity1 , estimating amygdala volumes, to determine whether @entity75 might be detected. METHODS: Review of video EEG monitoring data yielded 11 @entity1 with EEG lateralised @entity1315 and normal structural imaging. Amygdala volumes were estimated in this group, in 77 @entity1 with pathologically verified @entity131 ( @entity131 ), and in 77 controls. RESULTS: Seven of 11 "imaging-negative" cases had both significant amygdala asymmetry and @entity1283 , concordant with @entity410 lateralisation. Although significant amygdala asymmetry occurred in 35 of 77 @entity131 @entity1 , it was never attributable to an @entity717 . Compared with @entity1 with @entity131 , @entity1 with @entity1283 were less likely to have suffered secondarily generalised @entity410 (p<0.05), and had an older age of @entity410 onset (p<0.01). CONCLUSION: Abnormal @entity1283 is reported in seven cases of "imaging-negative" @entity1315 . Such abnormalities are not observed in @entity1 with @entity131 . It is postulated that @entity1283 may be attributable to a @entity851 or low grade @entity5 . It is suggested that amygdala volumetry is indicated in the investigation and diagnosis of "imaging-negative" @entity1315 .
