Diagnosis and treatment of @entity1504 in XXXX .

@entity1 @entity64 @entity6249 @entity75 @entity73 @entity303 @entity1504
UNASSIGNED: This paper provides an overview of @entity73 due to vascular @entity75 , which is referred to as vascular @entity73 (VCI). Over the past decades, we have seen marked progress in detecting VCI, both through maturation of diagnostic concepts and through advances in brain imaging, especially MRI. Yet in daily practice, it is often challenging to establish the diagnosis, particularly in @entity1 where there is no evident temporal relation between a cerebrovascular event and @entity73 . Because @entity1504 is such a common cause of @entity73 , it provides an obvious target for treatment. In @entity1 whose @entity73 follows directly after a @entity64 , the etiological classification of this @entity64 will direct treatment. In many @entity1 however, VCI develops due to so-called "silent @entity1504 ," without evident cerebrovascular events. In these @entity1 , @entity6249 ( @entity6249 ) are the most common cause. Yet no SVD-specific treatments currently exist, which is due to incomplete understanding of the pathophysiology. This review addresses developments in this field. It offers a framework to translate diagnostic criteria to daily practice, addresses treatment, and highlights some future perspectives. This article is part of a Special Issue titled "Vascular Contributions to @entity73 and @entity303 ," edited by M. Paul Murphy, Roderick A. Corriveau, and Donna M. Wilcock.
