Multimodality Intravascular Imaging to Predict Periprocedural XXXX During Percutaneous Coronary Intervention.

@entity1 @entity453 @entity6949 @entity583
OBJECTIVES: The aim of this study is to compare the relative merits of optical coherence tomography (OCT), intravascular ultrasound (IVUS), and near infrared spectroscopy (NIRS) in @entity1 with @entity453 for the prediction of periprocedural @entity583 ( @entity583 ). BACKGROUND: Although several individual intravascular imaging modalities have been employed to predict periprocedural @entity583 , it is unclear which of the imaging tools would best allow prediction of this complication. METHODS: We retrospectively analyzed 110 @entity1 who underwent OCT, IVUS, and NIRS. Periprocedural @entity583 was defined as a post-procedural @entity6949 ( @entity6949 ) elevation above 3* the upper limit of normal; analysis was also performed for @entity6949  >= 5* the upper limit of normal. RESULTS: @entity6949  >= 3* was observed in 10 @entity1 (9%) and 8 @entity1 had @entity6949  >= 5*. By OCT, minimum cap thickness was significantly lower (55 vs. 90  m, p  < 0.01), and the plaque burden by IVUS (84    9% vs. 77    8%, p  < 0.01) and maximum 4-mm lipid core burden index by NIRS (556 vs. 339, p  < 0.01) were greater in the @entity6949  >= 3* group. Multivariate logistic regression analysis identified cap thickness as the only independent predictor for @entity6949  >= 3* the upper limit of normal (odds ratio [OR]: 0.90, p  = 0.02) or @entity6949  >= 5* (OR: 0.91, p  = 0.04). If OCT findings were excluded from the analysis, plaque burden (OR: 1.13, p  = 0.045) and maximum 4-mm lipid core burden index (OR: 1.003, p  = 0.037) emerged to be the independent predictors. CONCLUSIONS: OCT-based fibrous cap thickness is the most important predictor of periprocedural @entity583 . In the absence of information about cap thickness, NIRS lipid core or IVUS plaque burden best determined the likelihood of the periprocedural event.
