Biosynthesis and the conjugation of XXXX nanoparticles with luteinizing hormone releasing hormone (LHRH).

@entity3703 @entity0 @entity26408 @entity31983
This paper presents the results of an experimental study of the biosynthesis of @entity3703 nanoparticles (BMNPs) with particle sizes between 10nm and 60nm. The biocompatible magnetic nanoparticles are produced from @entity31983 (M.M.) bacteria that respond to magnetic fields. M.M. bacteria were cultured and used to synthesize @entity3703 nanoparticles. This was done in an enriched magnetic spirillum growth medium (EMSGM) at different pH levels. The nanoparticle concentrations were characterized with UV-Visible (UV-Vis) spectroscopy, while the particle shapes were elucidated via transmission electron microscopy (TEM). The structure of the particles was studied using X-ray diffraction (XRD), while the hydrodynamic radii, particle size distributions and polydispersity of the nanoparticles were characterized using dynamic light scattering (DLS). @entity26408 reduction was also used to functionalize the BMNPs with a molecular recognition unit (luteinizing hormone releasing hormone, LHRH) that attaches specifically to receptors that are over-expressed on the surfaces of most @entity0 cell types. The resulting nanoparticles were examined using Fourier Transform Infrared (FTIR) spectroscopy and quantitative image analysis. The implications of the results are then discussed for the potential development of magnetic nanoparticles for the specific targeting and treatment of @entity0 .
