[Pineal peptides in the regulation of milk-ejection reflex in lactating XXXX ].

@entity35 @entity398 @entity291
The effects of pineal peptides (mol. mass 1-4 kDa) intranasal infusions on some parameters of milk-ejection reflex were investigated. Peptides were extracted from dairy- @entity291 pineal glands. Pineal peptides increase body weight, levels of water intake, plasma prolactin concentration and milk yield in @entity35 when infusing daily in dose 1 microgram/kg from the third day of lactation. On 9th and 12th days of lactation during 1-hour nursing seance the significantly greater number of reflective milk ejections were found. When 1 hour before the peptides infusion @entity35 were intraperitoneally injected by rabbit antiserum to @entity398 (200 microliters at dilution of 1:20) the effects of pineal peptides were significantly less expressive or were absent at all. Using enzymimmunoassay it was demonstrated that there were greater increasing of @entity398 content in pineal gland in suckling-induced @entity398 release from neurohypophysial system in the chronic pineal peptides-treated female @entity35 compared with control. This effect was absent when @entity35 were injected by @entity398 antibodies. These data suggest that pineal peptides can participate in forming of reflect @entity398 release pattern. This pattern is initiated by suckling and is limited by @entity398 content in blood.
