Studies on the antimycotic activity of XXXX .

@entity1 @entity66 @entity28578 @entity4895 @entity9869
The antimycotic effect of @entity9869 (FOA) was studied in experimental and clinical conditions. The experiments in vitro were performed on 21 strains of fungi isolated mainly from clinical material. The effect of FOA was compared with those of the structurally related drug @entity4895 . The clinical study was performed on 40 @entity1 aged 18 to 75 years with @entity66 . FOA in different dosage forms was applied topically 2 to 3 times daily for 30 days. Microscopic and cultured mycological studies were performed before and after treatment. The results showed that FOA possesses a well-expressed anticandidal effect close to that of @entity4895 , as well as moderate antidermatophytal effects. Clinical studies of 1% FOA cream showed good therapeutic effects similar to that of @entity28578 . Whitfield, but 55% of the @entity1 developed relapse of the lesions after discontinuation of the treatment. Higher concentrations of FOA included in milk suspension and powder induced severe side effects of local irritability.
