Cocktail therapy for femoral XXXX of the hip.

@entity1 @entity39 @entity561 @entity26 @entity236
INTRODUCTION: Cocktail therapy consists of extracorporeal shock wave treatment (ESWT), hyperbaric @entity26 therapy (HBO) and @entity561 . We hypothesized that this combined therapy may produce better results than ESWT alone when treating hip @entity39 . METHODS: This prospective, randomized study evaluated the effectiveness of cocktail therapy in early hip @entity39 , and then compared it to shock wave treatment alone. Sixty-three @entity1 (98 hips) were randomly divided into two groups. Group A consisted of 28 @entity1 (50 hips) who received cocktail therapy, and group B consisted of 35 @entity1 (48 hips) who received only ESWT. Each affected hip was treated with 6,000 shocks of ESWT at 28 kV (equivalent to 0.62 mJ/mm2) in a single session. Cocktail @entity1 also received HBO therapy performed in a multi-place chamber daily for 20 treatments, and they were administered 70 mg of @entity561 orally per week for 1 year. The evaluations included clinical assessment, radiograph and MRI. RESULTS: After a minimum of 2-years of follow-up, the overall results showed 74% improved, 16% unchanged and 10% worsened in group A; and 79.2% improved, 10.4% unchanged and 10.4% worsened in group B (P = 0.717). Total hip replacement (THR) was performed for 10% of group A and 10.4% of group B (P = 0.946). MRI showed significant reduction in @entity236 and a trend of decrease in the size of the lesions in both groups, however, no difference was noted between the two groups. Cocktail therapy is effective for early hip @entity39 , but the results are comparable to ESWT in short-term follow up. The joint effects of HBO and @entity561 over EWST were not observed. CONCLUSION: Long-term results are needed to determine whether or not the synergistic effects of ESWT, HBO and @entity561 over ESWT alone exist in early hip @entity39 .
