Cytologically malignant margins of wedge resected stage I XXXX .

@entity1 @entity5 @entity73 @entity957 @entity1149 @entity420
BACKGROUND: We have developed a novel test for the surgical margin of @entity5 using a cytologic technique (the run-across method in which a glass slide is run across the staple site), and we have assessed whether this method is useful in predicting margin relapse and prognosis. METHODS: From April 1996 to March 1999, 15 lesions of stage I @entity1149 ( @entity1149 ) (maximum diameter ranged from 10 to 35 mm with a median of 20 mm) from 15 @entity1 with @entity73 were excised without additional proximal resections. The surgical margin was examined using the run-across method. There were 8 male 7 female @entity1 whose ages ranged from 51 to 80 years. One @entity1 underwent video-assisted thoracic surgery and 14 underwent thoracotomy. The preoperative diagnoses of the @entity1 were 13 @entity420 , @entity957 , and 1 undiagnosed lesion (1 @entity420 ). The follow-up period ranged from 37 to 63 months. RESULTS: The rate of positive cytology was 47% in comparison with the rate of positive histology of 20%. There were 4 @entity1 with margin relapse (3 of them contained negative histology margins) at a rate of 57% among the positive cytology @entity1 in comparison with 0% among the negative cytology @entity1 (p = 0.03). In a comparison of survival between the negative cytology group and the positive cytology group, there were no statistically significant differences. CONCLUSIONS: The run-across method is also useful in confirming complete resection. A positive cytology margin could lead to margin relapse even if a @entity1149 is resected with a negative histology margin.
