XXXX of the Miyoshi type.

@entity1 @entity121 @entity3986 @entity425 @entity29730 @entity194 @entity291
OBJECTIVE: @entity29730 is an @entity3986 . It is characterized by distal muscle involvement, especially the gastrocnemius and soleus. The disease starts with @entity425 and @entity194 of the @entity291 . MATERIAL AND METHODS: Here we report on 2 @entity1 , brother and sister, from a Turkish family. Onset of the disease was at the age of 20 and 26 years of age, respectively. In both siblings, there was an early and predominant involvement of the distal muscles of the lower limbs. Creatine kinase activity was elevated 50- to 100-fold above normal values. RESULTS: Electromyography revealed a @entity121 pattern. Histology of the biceps muscles indicated some @entity121 changes consistent with @entity3986 . Occurrence in only these 2 siblings with no other family members was indicative of an autosomal recessive inheritance. CONCLUSIONS: We describe the distinctive clinical features in 2 siblings of a Turkish family with MM as differential diagnosis and histological change.
