Deep brain stimulation and XXXX in @entity191 : The predictive value of electroencephalography.

@entity1 @entity73 @entity9221 @entity191 @entity1010
UNASSIGNED: Some @entity191 ( @entity191 ) @entity1 treated with subthalamic nucleus deep brain stimulation ( @entity9221 -DBS) develop new-onset @entity73 . We examined whether clinical EEG recordings can be used to predict @entity73 in @entity191 @entity1 undergoing @entity9221 -DBS. In this retrospective study, we used the Grand Total EEG (GTE)-score (short and total) to evaluate pre- and postoperative EEGs. In @entity191 @entity1 undergoing @entity9221 -DBS (N  =  30), cognitive functioning was measured using Mini-Mental State Test and DemTect before and after surgery. Severity of motor impairment was assessed using the Unified @entity191 Rating Scale-III. @entity1 were classified into @entity1 with or without @entity73 after @entity9221 -DBS surgery. Epidemiological data, pre- and postoperative EEG recordings as well as neuropsychological and neurological data, electrode positions and the third ventricle width were compared. A logistic regression model was used to identify predictors of @entity73 . Motor deficits significantly improved from pre- to post-surgery, while the mean GTE-scores increased significantly. Six @entity1 developed @entity73 4-12  months postoperatively. These @entity1 had significantly higher preoperative GTE-scores than @entity1 without @entity73 , although preoperative cognitive functioning was comparable. Electrode positions, @entity1010 and neurological data did not differ between groups. Logistic regression analysis identified the GTE-score as a significant predictor of postoperative @entity73 . Data suggest that the preoperative GTE-score can be used to identify @entity191 @entity1 that are at high risk for developing @entity73 after @entity9221 -DBS surgery even though their preoperative cognitive state was normal.
