Clinical outcome and complications of gamma knife radiosurgery for XXXX .

@entity1 @entity7026 @entity2758 @entity510 @entity16
UNASSIGNED: We sought to evaluate the outcome of @entity7026 ( @entity2758 ) treated with gamma knife radiosurgery (GKRS) (Elekta, Stockholm, Sweden) as a primary treatment as well as an adjunct therapy. GKRS has emerged as an important treatment option for intracranial @entity2758 . However, the long term outcome of GKRS on @entity2758 is not well understood. We performed a retrospective review of 85 @entity1 with @entity2758 from 2000-2012 who received GKRS. Out of 85 @entity1 , 13 had undergone prior embolization. The study population was monitored clinically and radiographically after GKRS treatment. Outcome following GKRS for intracranial @entity2758 showed significant variations in nidus obliteration (obliteration in 67 [79%] @entity1 and increase of nidus size on MRI in 18 [21%] @entity1 ). The median time to nidus obliteration was 31 months. Overall two (2.3%) @entity1 had @entity510 and the annual bleeding risk was 1.6% after GKRS. Predictive factors for obliteration of the nidus in @entity1 with @entity2758 were low @entity2758 score, Spetzler-Martin grade I-III and female sex. Seventeen (20%) and one (1.17%) @entity1 underwent repeat GKRS and resection, respectively, after initial GKRS, due to increased size of the nidus and GKRS related cyst formation. Thus, GKRS offers a high obliteration rate of @entity2758 , low risk of @entity510 and @entity16 , both as primary modality and as an adjunctive treatment. Therefore, GKRS is an effective treatment option for new @entity1 with @entity2758 as well as an adjuvant therapy in @entity1 with recurrent @entity2758 .
