Polyarteritis nodosa presenting as XXXX .

@entity1 @entity121 @entity573 @entity1333 @entity262 @entity425 @entity1011 @entity925 @entity221 @entity6558
BACKGROUND: Skeletal muscle involvement has been well documented in @entity1 with @entity573 nodosa (PAN), and symptoms referable to skeletal muscle are not uncommon. However, @entity6558 as a mode of presentation of PAN is uncommon. This unusual presentation of PAN has been reported only once previously in the English literature. OBJECTIVE: This study describes a @entity1 who had diffuse weakness, @entity925 , and markedly elevated serum @entity1011 phosphokinase, mimicking @entity6558 . The literature dealing with the clinical aspects of muscle involvement in PAN is reviewed. RESULTS: A 24-year-old @entity1 was admitted to the hospital with a 1-month history of @entity221 , @entity925 , and @entity425 . @entity1333 was shown on subsequent muscle biopsy, consistent with PAN. Literature review indicated that muscle involvement is common in PAN, as has been shown by the frequency of muscular symptoms and by histologic evidence obtained from both clinical and autopsy studies. Nineteen percent of @entity1 with PAN had documented @entity121 , and autopsy series have shown skeletal muscle involvement in 30% to 48% of cases. However, @entity6558 as a mode of presentation of PAN is rare. We found only 1 other @entity1 with PAN who had elevated @entity1011 phosphokinase and diffuse @entity121 suggestive of @entity6558 . CONCLUSIONS: PAN should be suspected in cases of focal or diffuse @entity121 , especially in the context of a @entity262 . Biopsy of symptomatic muscles or EMG-directed biopsies can be helpful in establishing a diagnosis of PAN to allow the physician to provide early treatment.
