[Differential proteomic analysis of thalamus in XXXX with @entity21 ].

@entity35 @entity21 @entity131 @entity130
OBJECTIVE: To examine the differential expression of protein of thalamus in @entity35 with @entity21 . METHODS: Twenty-five @entity35 were randomly divided into a normal group (n=10) and a @entity130 group (n=15). Total proteins of @entity131 tissue and normal brain tissue were extracted separately, and then proteins were separated by two dimensional gel electrophoresis and stained with Coomassie brilliant blue. The differentially expressed protein spots were identified with biospectrometry. Images were analyzed by PDQuest 7.0. RESULTS: The distribution of protein spots in the @entity130 group was similar to that of the normal group, the matching rate was 95%, and the repeatability was good. Proteins were mainly displayed at pI 3-8, with relative molecular mass 14.4-75.0 kD. Compared with the normal group, 16 spots of proteins increased and 18 spots of proteins decreased in the @entity130 group. CONCLUSION: There is some difference in protein expression between the normal group and the @entity130 group. @entity131 may lead to changes of proteins in the thalamus.
