Needleless transcutaneous electroacupuncture improves rectal distension-induced impairment in intestinal motility and slow waves via vagal mechanisms in XXXX .

@entity1944 @entity235 @entity5584 @entity292 @entity3897 @entity694
AIM: This study was designed to compare the effects and mechanisms of transcutaneous electroacupuncture (TEA) on @entity5584 ( @entity5584 )-induced @entity1944 with EA. METHODS: six female @entity235 chronically implanted with a @entity292 , a proximal @entity694 and intestinal serosal electrodes were studied. EA and TEA were performed via needles and cutaneous electrodes placed at bilateral ST-36 (Zusanli) acupoints respectively; their effects on postprandial @entity1944 (slow waves, contractions and transit) induced by @entity5584 , and autonomic functions were compared. RESULTS: @entity5584 at a volume of 140 ml suppressed intestinal contractions; the motility index was reduced with @entity5584 (P = 0.001). Both EA and TEA ameliorated the suppressed contractions (P = 0.003 and 0.001) and their effects were comparable. @entity5584 reduced the percentage of normal intestinal slow waves (P = 0.002) that was increased with both EA and TEA (P = 0.005 and 0.035). No significant difference was noted between EA and TEA. EA and TEA reduced small bowel transit time (P = 0.001 and 0.007); these prokinetic effects were blocked by @entity3897 . Both EA and TEA increased vagal activity assessed by the spectral analysis of heart rate variability (both P = 0.03). CONCLUSION: @entity5584 inhibits postprandial intestinal motility. Both EA and TEA at ST-36 are able to improve the @entity5584 -induced impairment in intestinal contractions, transit and slow waves mediated via the vagal mechanism. Needleless TEA is as effective as EA in ameliorating the @entity1944 .
