Addition of Intrathecal XXXX to @entity1341 for Spinal Anesthesia in Cesarean Section.

@entity1 @entity2399 @entity1337 @entity1341 @entity158 @entity1760
BACKGROUND: Spinal anesthesia is widely used for caesarean section. Addition of intrathecal @entity2399 to local anesthetics seems to improve the quality of block and prolong the duration of @entity1337 . OBJECTIVES: The present study was designed to examine whether addition of intrathecal @entity2399 enhances the analgesic efficacy of intrathecal @entity1341 in @entity1 undergoing cesarean section. @entity1 AND METHODS: We conducted a randomized, prospective, double-blind, case-control, clinical trial. Eighty @entity1 were scheduled for cesarean section under spinal anesthesia. The @entity1 were randomly allocated to receive either 10 mg of hyperbaric @entity1341 0.5% (control group) or 10 mg of hyperbaric @entity1341 0.5% plus 50 mg @entity2399 (case group) intrathecally. Hemodynamic variability, onset and duration of block and duration of @entity1337 were evaluated. RESULTS: The onset of sensory blockade was delayed in case group compared with control group, and this was statistically significant. The onset of motor blockade had no difference in both groups. The duration of motor blockade was similar. Post-operative @entity1337 was longer in @entity2399 group but the difference was not meaningful. The intraoperative hemodynamic variability showed no significant differences between groups. CONCLUSIONS: This study showed that the addition of intrathecal @entity2399 to @entity1341 is not desirable in @entity1 undergoing cesarean section due to the delay in the onset of sensory blockade and the lack of significant effects of @entity1760 on post-operative @entity158 .
