Urgency and urge XXXX in an older population: ten-year changes and their association with mortality.

@entity1 @entity4736 @entity322 @entity167 @entity102 @entity717
BACKGROUND AND AIMS: Urgency and urge @entity322 are common urinary symptoms among older @entity1 , both @entity1 and @entity1 . The aim of this population-based prospective cohort study was to examine the independent association of urgency and urge @entity322 with 10-year mortality in older @entity1 and @entity1 , and to describe the changes in these symptoms during those 10 years. METHODS: At baseline, 1052 @entity1 (524 @entity1 and 528 @entity1 ) aged 60-89, selected by random sampling and stratified by 5-year age group and sex, were interviewed for the Tampere Longitudinal Study on Ageing. In 10 years, 541 @entity1 had died, and 435 @entity1 (175 @entity1 and 260 @entity1 ) were re-interviewed. Cox proportional hazards models were used to examine the independent association of urgency and urge @entity322 in each gender with 10-year mortality, adjusted for age, @entity102 , activities of daily living (ADL) disability, socioeconomic status, smoking and @entity167 use. RESULTS: In 10 years, 86% of @entity1 and 54% of @entity1 who reported at least urgency at baseline had died. The respective figures for @entity1 and @entity1 without urgency were 57 and 38%. Adjusted for age, both urgency without @entity322 (Risk Ratio 1.87; 95% Confidence Interval 1.28-2.74) and urge @entity322 (RR 3.13; 95% CI 2.054.77) significantly predicted mortality in @entity1 , while only urge @entity322 was a statistically significant predictor in @entity1 ( @entity4736 .63; 95% CI 1.03-2.57). After further adjusting for @entity102 and @entity717 , urge @entity322 lost its predictive power ( @entity4736 .44; 95% CI 0.88-2.23) in @entity1 , while the significant predictive power of urgency alone and urge @entity322 in @entity1 persisted even after additional adjustment for socioeconomic status, smoking and @entity167 use ( @entity4736 .80; 95% CI 1.20-2.71, and @entity4736 .97; 95% CI 1.25-3.10, respectively). CONCLUSIONS: Urgency and urge @entity322 are significant prognostic indicators of mortality especially in older @entity1 . This emphasizes the importance of evaluation and treatment of urinary symptoms as a part of comprehensive geriatric assessment and management.
