Clinical characteristics of Japanese XXXX with severe @entity2298 .

@entity1 @entity2298 @entity788 @entity230 @entity981 @entity1560 @entity6 @entity0 @entity1375 @entity7961 @entity4445 @entity412 @entity30176 @entity453 @entity285 @entity288
BACKGROUND: Although of interest, few data exist on the clinical characteristics of Japanese @entity1 with an extremely high @entity412 level (>= 1000  mg/dL). OBJECTIVE: We assessed the clinical characteristics of Japanese @entity1 with an extremely high @entity412 level. METHODS: We investigated the presence of @entity453 , history of @entity788 , the presence of @entity1560 , and the potential causes of elevated @entity412 in Japanese subjects with an extremely high level of fasting @entity412 (>= 1000  mg/dL) among 70,368 subjects whose serum @entity412 was measured for any reason at Kanazawa University Hospital from April 2004 to March  2014. RESULTS: We identified 215 (0.31%) subjects (mean age, 46  years; male, 170, mean body mass index, 25  kg/m(2)) with severe @entity2298 . Among them, 4 (1.9%) subjects were classified as type I, 97 (45.1%) subjects were type IV, and 114 (53.0%) subjects were @entity30176 , according to Fredrickson's classification. Among 215 subjects, 116 subjects (54.0%) drank @entity285 , 58 (27.0%) showed heavy intake (>= 60  g/d), and 64 (29.8%) subjects had @entity6 . In total, 59 (27.4%) subjects had transient severe @entity2298 caused by @entity288 (N  =  19), antidepressant (N  =  18), @entity4445 and @entity230 for @entity981 (N  =  15), hormone replacement therapy for @entity0 (N  =  9), b-blocker (N  =  5), @entity1375 (N  =  4), pregnancy (N  =  4), and @entity7961 (N  =  2). As many as 119 (55.3%) subjects exhibited @entity1560 . Moreover, 12 (5.6%) and 17 (7.9%) subjects had a history of @entity788 and @entity453 , respectively. CONCLUSIONS: A variety of situations can cause severe @entity2298 . We suggest that potential secondary causes should be carefully assessed for such @entity1 .
