Arteriographic predictors of spontaneous improvement in left ventricular function after XXXX .

@entity1 @entity583 @entity1188 @entity908
To better characterize the changes in left ventricular ejection fraction after @entity583 , we compared radionuclide ventriculograms obtained acutely and 2 weeks after @entity583 in 40 @entity1 . These @entity1 underwent angiography within a mean of 4 hr and 20 min after the onset of symptoms of @entity1188 and either received no therapy (32 @entity1 who were control subjects in a thrombolysis trial) or did not experience reperfusion (eight @entity1 ) despite receiving streptokinase infusions. In all 40 @entity1 , the change in left ventricular ejection fraction over 2 weeks was small (+2.6%). @entity1 were then grouped according to the presence or absence of residual flow on their angiograms. Residual flow was considered to be present in 21 @entity1 , in 12 by virtue of subtotal occlusion of the artery supplying the area of @entity1188 and in nine because of well-developed coronary collaterals to the @entity1188 . Mean change in ejection fraction for @entity1 with residual flow was +6.9 +/- 2.3% vs -2.2 +/- 1.7% for @entity1 without residual flow (p less than .01). Fourteen of 21 (67%) @entity1 with residual flow had a spontaneous rise in ejection fraction of greater than 5%, as compared with two of 19 (11%) @entity1 without residual flow (p less than .01). Time to peak level of @entity908 kinase (CK) was significantly shorter in the residual flow group (15 vs 23 hr, p less than .01), while the peak level of CK was lower (1550 vs 2220 IU) in these @entity1 . This latter difference did not reach statistical significance (p = .10).(ABSTRACT TRUNCATED AT 250 WORDS)
