The localization of matrix metalloproteinases-8 and -13 in XXXX , deep-meatal and post-auricular skin: a comparative analysis.

@entity1 @entity3540 @entity5952 @entity1550
CONCLUSION: The presence of @entity5952 and @entity1550 was found to be significantly higher in @entity3540 compared with post-auricular skin. The results show that the control group used has implications for further studies. OBJECTIVES: To compare the presence of @entity5952 and @entity1550 in @entity3540 , deep meatal and post-auricular skin. Our null hypothesis was that there was no difference in expressions of @entity5952 and @entity1550 in the three groups. MATERIALS AND METHODS: The study was carried out in a secondary care specialist centre and used prospective retrieval of specimens for immunohistological localization of @entity5952 and @entity1550 . Eleven @entity1 undergoing @entity3540 surgery were recruited for the study. Eleven @entity3540 specimens, 10 deep meatal skin specimens and 10 post-auricular skin specimens were analysed. Specimens were analysed by immunohistochemistry using monoclonal antibodies to @entity5952 and @entity1550 . Two observers scored the slides independently in a blind fashion. RESULTS: The presence of @entity5952 and @entity1550 was found to be significantly higher in @entity3540 compared to post-auricular skin (p=0.02, p=0.03, respectively). There were no significant differences in expression of @entity5952 and @entity1550 between @entity3540 and deep meatal skin (p=0.08, p=0.09, respectively). There were no significant differences in the control groups.
