Interstitial fluid, lymph and XXXX formation.

@entity235 @entity4 @entity95 @entity450
Venous and interstitial fluid pressure, protein content of blood plasma, leg lymph and interstitial fluid were estimated in anaesthetized normal @entity235 and @entity95 as well as in @entity235 with chronic inferior v. cava constriction. In the tissue fluid collected by the perforated capsule and by the wick methods protein concentrations were the same. In the @entity95 hindlegs subcutaneous tissue fluid and lymph protein concentrations were 50 and 45%, respectively of plasma protein concentration. In the @entity235 tissue fluid, protein was 42.5% but lymph protein content was only 17% of plasma protein. Tissue fluid hydraulic pressure (intracapsular) was in normal @entity235 --5.0 +/- 1.3 mm Hg and it increased in cava constricted @entity235 to +0.8 +/- 0.4 mm Hg. In caval constriction, protein concentration in the interstitial fluid decreased markedly. A linear relationship was found in @entity235 and @entity95 between tissue fluid and lymph protein concentration (r = 0.68 and 0.73, respectively). The relationship between venous and tissue fluid (intracapsular) pressures was non-linear. In @entity235 hindlimbs the calculated isogravimetric capillary pressure was 7.8 mm Hg. In @entity450 both the increase of interstitial fluid hydraulic pressure, and the decrease of oncotic pressure ace as " @entity4 safety factors". In the @entity95 20 h after the intravenous injection of labelled albumin there was no significant difference between the specific radioactive albumin contents of plasma, leg lymph and tissue fluid.
