@entity788 and XXXX : Quantitative Assessment with Preoperative Multiparametric MR Imaging.

@entity1 @entity788 @entity82 @entity254 @entity3472 @entity292
Purpose To evaluate the diagnostic performance of multiparametric pancreatic magnetic resonance (MR) imaging, including the T2*-corrected Dixon technique and intravoxel incoherent motion (IVIM) diffusion-weighted (DW) imaging, in the quantification of @entity788 and @entity82 , with histologic analysis as the reference standard, and to determine the relationship between MR parameters and @entity3472 . Materials and Methods This retrospective study was approved by the institutional review board, and the informed consent requirement was waived. A total of 165 @entity1 (93 @entity1 , 72 @entity1 ; mean age, 62 years) underwent preoperative 3-T MR imaging and subsequent pancreatectomy (interval, 0-77 days). Fat fractions, IVIM DW imaging parameters (true diffusion coefficient [D], pseudodiffusion coefficient [D*], and perfusion fraction [f]), pancreas-to-muscle signal intensity ratios on unenhanced T1-weighted images, and pancreatic duct sizes were compared with the fat fractions and @entity82 degrees (F0-F3) of specimens. In 95 @entity1 who underwent pancreatoenteric @entity254 , MR parameters were compared between groups with clinically relevant @entity3472 and those without. The relationship between @entity3472 and MR parameters was evaluated by using logistic regression analysis. Results Fat fractions at MR imaging showed a moderate relationship with histologic findings (r = 0.71; 95% confidence interval: 0.63, 0.78). @entity1 with advanced @entity82 (F2-F3) had lower D*([39.72    13.64] *10(-3)mm(2)/sec vs [32.50    13.09] *10(-3)mm(2)/sec [mean    standard deviation], P = .004), f (29.77%    8.51 vs 20.82%    8.66, P < .001), and unenhanced T1-weighted signal intensity ratio (1.43    0.26 vs 1.21    0.30, P < .001) than did @entity1 with F0-F1 disease. Clinically relevant @entity292 developed in 14 (15%) of 95 @entity1 , and f was significantly associated with @entity3472 (odds ratio, 1.17; 95% confidence interval: 1.05, 1.30). Conclusion Multiparametric MR imaging of the pancreas, including imaging with the T2*-corrected Dixon technique and IVIM DW imaging, may yield quantitative information regarding @entity788 and @entity82 , and f was shown to be significantly associated with postoperative @entity3472 . (  ) RSNA, 2015 Online supplemental material is available for this article.
