The natural history of untreated XXXX .

@entity1 @entity1653 @entity5 @entity1297
BACKGROUND: This study was undertaken to determine the natural history of untreated @entity1297 . Although there are reports on the natural history of @entity1653 , most series contain only a few cases of @entity1653 involving the skull base. Natural history information is important when recommending treatment and evaluating results. METHODS: The case records and imaging studies of 40 @entity1 with @entity1297 from a single practice were reviewed. These @entity1 either did not receive treatment or there was a long delay from the onset of symptoms to the initiation of treatment. RESULTS: Skull base @entity1653 may be very indolent @entity5 . @entity1 with these @entity5 have lived long, comfortable, and relatively productive lives without treatment or with delayed treatment. Impairment may be much less than imaging studies would suggest. CONCLUSION: The authors are not advocating that @entity1297 not receive treatment. However, their unique experience with this group of @entity1 provides convincing evidence that the indolent behavior of some @entity1297 must be considered when recommending various surgical and radiation procedures and interpreting their results in relationship to the functional outcome of the @entity1 .
