Changing site distribution of XXXX in Japan.

@entity1 @entity694 @entity5 @entity14
PURPOSE: In North America and other high-risk areas, there has been a proximal shift in the subsite distribution of @entity14 . We wanted to determine whether any similar change has occurred in Japan, and where the incidence of this disease has increased sharply. METHODS: Data from the Reports of the Japanese Society for @entity694 and Rectum were used to analyze the time trend of @entity14 in Japan between 1974 and 1994 according to the @entity1 ' age at diagnosis and sex, and the site of the @entity5 within the colon or rectum. RESULTS: The percentage of @entity1 over the age of 70, especially females, increased. The increase in the percentage of right-sided @entity694 in @entity14 cases was accompanied by a continuous decline in the percentage of @entity5 in both sexes at all ages. In general, the percentage of right-sided @entity694 in @entity694 cases was stable in @entity1 , but increased in @entity1 . The rate among @entity1 older than 70 years increased in @entity1 , but predominated and remained stable in @entity1 . No proximal shift in @entity694 was found in either sex under the age of 69. CONCLUSION: These findings indicated that a proximal shift in the subsite distribution of @entity14 has occurred in Japan. This rightward shift of @entity14 is due to the decreasing proportion of @entity5 . Furthermore, the increasing proportion of older @entity1 , especially females, may be another major determinant of the changing @entity694 subsite distribution.
