@entity65 risk factors in 2 distinct ethnic groups: Indian and Pakistani compared with American premenopausal XXXX .

@entity1 @entity167 @entity1674 @entity15449 @entity65 @entity165
BACKGROUND: Although @entity1 from the Indian subcontinent have high rates of @entity65 ( @entity65 ), studies of such in Indian and Pakistani @entity1 living in the United States are lacking. OBJECTIVE: This study accounted for variability in serum lipid (total @entity165 and @entity1674 ) and lipoprotein [LDL @entity165 , lipoprotein(a), and HDL @entity165 ] concentrations in Indian and Pakistani compared with American premenopausal @entity1 in the United States. Body composition, regional fat distribution, dietary intake, and energy expenditure were compared between groups. DESIGN: The 2 groups were 47 Indian and Pakistani and 47 American @entity1 . Health was assessed via medical history, physical activity, body composition (via anthropometry and dual-energy X-ray absorptiometry), dietary intake (via 7-d food records), and serum lipids. RESULTS: Serum total @entity165 , @entity1674 , LDL @entity165 , lipoprotein(a), the ratio of total to HDL @entity165 , and the ratio of LDL to HDL @entity165 were greater (P <0.03), whereas HDL- @entity165 values were lower (P = 0.011) in Indians and @entity15449 than in Americans. Multiple regression analysis indicated that approximately 18% of the variance in total @entity165 (P = 0.0010) and LDL @entity165 (P = 0.0009) was accounted for by ethnicity, energy expenditure, and the ratio of the sum of central to the sum of peripheral skinfold thicknesses. Ethnicity, sum of central skinfold thicknesses, ratio of polyunsaturated to saturated fat, and monounsaturated fat intake accounted for approximately 43% of the variance in @entity1674 concentration (P < 0.0001). Monounsaturated fat, percentage body fat, and @entity167 intake accounted for approximately 26% of variance in HDL @entity165 . Ethnicity contributed approximately 22% of the 25% overall variance in lipoprotein(a). CONCLUSIONS: Results suggest that these Indian and Pakistani @entity1 are at higher @entity65 risk than their American counterparts, but that increasing their physical activity is likely to decrease overall and regional adiposity, thereby improving their serum lipid profiles.
