Narrow band imaging-assisted transurethral resection for non-muscle invasive XXXX significantly reduces @entity5 rate.

@entity5 @entity1 @entity150 @entity189
PURPOSE: To investigate whether narrow band imaging (NBI)-assisted transurethral resection (TUR) (NBI-TUR) has an impact on non-muscle invasive @entity150 (NMIBC) @entity5 rate compared to white light (WL)-assisted TUR (WL-TUR). METHODS: @entity1 with NMIBC treated with either NBI- or WL-TUR were compared in a frequency-matched index-control setting. During NBI-TUR, all suspicious lesions identified by either WL or NBI were resected. Index @entity1 (NBI-TUR, n  =  40) were prospectively recruited and control @entity1 (WL-TUR, n  =  120) were retrospectively collected, whilst being blinded for their first follow-up (fFU)-status. Non-radical TUR cases, @entity1 without evidence of @entity189 in the pathology specimen and those with @entity189 in situ or muscle invasive disease were excluded. Matching was based on the risk of @entity5 recurrence defined by (a) the EORTC risk score for recurrence and (b) the administration or not of one single chemotherapeutic intravesical instillation immediately after TUR. All @entity1 underwent routine follow-up with WL cystoscopy supplemented with cytology at 3 months or re-TUR in selected cases. The @entity5 rates at fFU (RR-fFU) of @entity1 with NMIBC submitted to either NBI- or WL-TUR were compared. RESULTS: Baseline @entity1 and @entity5 characteristics were comparable between groups. The RR-fFU for WL- and NBI-TUR was 30.5% (36 out of 118 @entity1 ) and 15.0% (6 out of 40 @entity1 ), respectively (OR: 2.7, one-sided 95% CI: 1.2-6.1; P  =  0.03). CONCLUSION: NBI-TUR decreases @entity5 rate significantly when compared to a matched cohort of WL-TUR.
