Rate of thyroglossal duct remnant visualization after total thyroidectomy for differentiated XXXX and its impact on clinical outcome of radioactive iodine (I-131) ablation.

@entity1 @entity1375 @entity227 @entity1955 @entity3745 @entity259 @entity4653
OBJECTIVES: The rate and impact of @entity227 in @entity1 with @entity1375 after total thyroidectomy for differentiated @entity259 (DTC) have not yet been fully determined. The aim of this study was to assess the rate of TGDR visualization in post total thyroidectomy @entity4653 ( @entity4653 ) for DTC and to evaluate its impact on the outcome of I-131 ablation. METHODS: A total of 60 consecutive DTC @entity1 (51 papillary thyroid Ca., and 9 Follicular thyroid Ca.), underwent total thyroidectomy, followed by @entity4653 (using I-131 in 28 @entity1 and I-123 in 32 @entity1 ), neck ultrasound (US), @entity3745 (Tg) and Tg anti-bodies (TgAb) assay after 40 days and subsequent I-131 ablation. At 6 months later follow-up I-131 @entity4653 , neck U/S, Tg and TgAb were performed following suspension of @entity1955 for 1-month (thyroid stimulating hormone [TSH] >30  IU/ml) in 53 @entity1 and following recombinant @entity1 TSH stimulation in seven @entity1 . RESULTS: Of the studied 60 @entity1 , 19/60 (31.7%) had a linear or focal radioactivity at the superior midline of the neck, suggesting TGDR (Group 1), and 41/60 (68.3%) had no uptake to suggest TGDR (Group 2). No significant difference regarding age, gender and histopathology between both groups. Neck US showed no evidence of thyroid tissue in the superior midline of the neck in both groups, and only a small or no residual thyroid tissue in @entity1 of Group 1. There was a significant successful I-131 ablation rate among @entity1 of group 1 compared to group 2 (79% in Group 1 vs. 41.5% in Group 2) (P = 0.007). CONCLUSIONS: Thyroglossal duct remnant visualization on @entity4653 of @entity1375 subjects after total thyroidectomy suggests presence of only a small or no residual functioning thyroid tissue at the thyroid bed and can predict a good response to I-131 ablation.
