Moderate Hypothermic Circulatory Arrest with Antegrade Cerebral Perfusion for Rapid Total Arch Replacement in Acute XXXX .

@entity1 @entity51 @entity7105 @entity3929 @entity1167 @entity1011 @entity1580 @entity2332
UNASSIGNED: Background   The optimal hypothermic level during @entity1167 is controversial. The aim of our study was to comprehensively assess the impact of moderate hypothermic @entity1167 with antegrade cerebral perfusion (ACP) on total aortic arch replacement. Methods   From 2010 to 2013, data were collected from 99 consecutive @entity1 with acute @entity1580 . All @entity1 underwent total arch replacement plus frozen @entity7105 trunk procedure. There were 51 @entity1 in the @entity1167 ( @entity1167 ) group and 47 in the @entity1167 ( @entity1167 ) group. Either unilateral or bilateral ACP was applied for cerebral protection. Perioperative data and measured outcomes were compared. Results   Overall mean @entity1167 time was 29.9        6.0 minutes. Temporary @entity51 incidence was lower in the @entity1167 group compared with the @entity1167 group (21.3 vs. 40.4%, p   =   0.041). The total 30-day mortality was 17.2% (14.9 vs. 19.2%, p   =   0.568) and permanent @entity51 morbidity was 3.0% overall. In @entity1167 , less blood products were used than in @entity1167 . Moderate @entity2332 was a protective factor for the composite outcome of temporary and permanent @entity51 (odds ratio   =   0.385; 95% confidence interval   =   0.162-0.919). Hypothermic level did not significantly affect the perioperative @entity3929 aminotransferase and serum @entity1011 levels. Conclusion   Within a short @entity1167 time, @entity1167 combined with ACP seemed to be a safe and effective method to protect cerebral and visceral organs during total aortic arch replacement.
