Relationship between body mass index and XXXX aminotransferase concentration in non-diabetic Korean adults.

@entity1 @entity28 @entity167 @entity42685 @entity1561 @entity493
BACKGROUND/OBJECTIVES: @entity28 has been identified as an important factor of elevated @entity493 aminotransferase (ALT), a surrogate of @entity1561 . We investigated the relationship between @entity28 and @entity42685 in the general Korean population. SUBJECTS/METHODS: The study sample was comprised of 3098 Korean adults who had participated in the 2005 Korean National Health and Nutrition Examination Survey. @entity28 was assessed using body mass index (BMI). Overweight (23< or =BMI<25) and @entity28 (BMI> or =25) were defined by the International @entity28 Task Force for Asian adults. ALT was measured by enzymatic methods. @entity42685 was defined as an enzyme activity >40 IU/l for @entity1 and >31 IU/l for @entity1 . RESULTS: Among @entity1 , 246 (12.7%) @entity1 and 86 (7.4%) @entity1 displayed @entity42685 . BMI was significantly higher in @entity1 and @entity1 with @entity42685 than those with normal ALT (P<0.0001). The unadjusted odds ratio (OR) for @entity42685 increased according to the degree of BMI in @entity1 (OR: 1.9, 95% confidence interval (CI): 1.25-2.93 in overweight vs OR: 5.01, 95% CI: 3.49-7.21 in @entity28 ; P<0.0001) and @entity1 (OR: 2.44, 95% CI: 1.24-4.82 vs OR: 3.94, 95% CI: 2.18-7.13; P<0.0001). This trend did not differ after adjustment for putative risk factors including @entity167 intake in @entity1 (OR: 1.56 vs OR: 3.47, P<0.0001) and @entity1 (OR: 1.55 vs OR: 3.10, P=0.0015). CONCLUSION: BMI is implicated as a strong risk factor of @entity42685 in non-diabetic Korean adults.
