Acute disseminated XXXX in childhood: report of 10 cases.

@entity1 @entity129 @entity410 @entity1667 @entity198 @entity66 @entity909 @entity281 @entity134 @entity1781 @entity1651 @entity230 @entity2055
We report 10 @entity1 with the diagnosis of acute disseminated @entity1651 . Diagnosis was based on clinical and radiologic findings, and after acute @entity198 was excluded by negative culture and antibody results. The most common presenting symptom was @entity2055 , followed by @entity1781 , @entity129 , @entity410 , @entity66 , and @entity909 . Brain magnetic resonance imaging showing bilateral symmetrical hyper-intense lesions of the same age in brain stem, subcortical white matter, thalamus, basal ganglia, or cerebellum was the mainstay of the diagnosis. The presence of a preceding event (either an @entity281 or vaccination) was present in 8 of 10 @entity1 . Brain computed tomographic scans were abnormal in 3 of 10, and electroencephalogram was normal in all @entity1 . High-dose corticosteroids were given to six @entity1 , one received low-dose @entity230 , and the other three had symptomatic follow-up. Those who relapsed were mainly from the symptomatic follow-up group. Only one @entity1 (the youngest) receiving high-dose @entity1667 relapsed. Therefore, early high-dose @entity134 treatment seems to be the most effective treatment in acute disseminated @entity1651 and can prevent relapses.
