Quality of life in XXXX and its relationship with visual function.

@entity1 @entity227 @entity5494 @entity726 @entity717
PURPOSE: The aims of this study were (a) to explore @entity1 self-reported @entity227 resulting from @entity726 by means of a questionnaire developed for this purpose; (b) identify activities strongly associated with a measure of @entity227 , (c) to quantify different psychophysical aspects of visual function; (d) to assess the relationship between objective measures of visual function and @entity1 ' perception of their vision-related quality of life. @entity1 AND METHODS: Three groups of @entity726 @entity1 (n = 47) with mild (n = 18), moderate (n = 19), and severe @entity227 (n = 10) and a group of normal controls (n = 19) underwent a comprehensive clinical examination, completed a questionnaire and, on a separate visit, performed a number of psychophysical tests of visual function. MAIN OUTCOME MEASURES: Questionnaire responses (vision-related quality of life, general health and psychosocial variables), visual acuity, visual fields, Esterman binocular disability scores, contrast sensitivity, critical flicker frequency, color vision, dark adaptation, @entity717 (brightness acuity), and stereoacuity scores were measured. RESULTS: Fifteen of the 50 questions were noted to have a strong significant relationship with a measure of @entity227 and were included in a new questionnaire scale, the @entity726 Quality of Life - 15 (GQL-15). The scale validity showed a significant correlation with perimetric @entity5494 ( @entity5494 ) values (r = -0.6; P < 0.0001), the reliability of the scale was high (Cronbach alpha = 0.95), and test-retest reliability of the questionnaire was strong (r = 0.87). An overall statistically significant decrease in performance-related quality of life was noted between normal subjects and all groups of @entity726 @entity1 . A significant relationship was found between the scale questionnaire summary performance measure and a number of psychophysical tests: Pelli-Robson contrast sensitivity (r = -0.45, P < 0.001), @entity717 (r = -0.41, P < 0.001), Esterman binocular visual field test (r = -0.39, P < 0.001), dark adaptation (r = 0.34, P = 0.007), and stereopsis (r = 0.26, P = 0.04). CONCLUSION: Perceived @entity227 relating to certain tasks (particularly involving dark adaptation and disability glare, activities demanding functional peripheral vision such us tripping over and bumping into objects and outdoor mobility tasks) was significantly associated with the severity of binocular @entity227 . As a result, a new @entity726 -specific questionnaire scale with good performance characteristics is presented in this study. The difficulties encountered by @entity1 in everyday life (as measured with the questionnaire) were also mirrored in their performance on a number of psychophysical tests, especially contrast sensitivity, @entity717 , Esterman binocular visual field test, and dark adaptation.
