End Stage Renal Disease as a Potential Risk Factor for XXXX .

@entity1 @entity2298 @entity455 @entity101 @entity6 @entity1007 @entity2994 @entity65 @entity454
UNASSIGNED: @entity454 ( @entity454 ) has been reported to be an important risk factor for @entity455 . @entity2994 ( @entity2994 ) is closely related with @entity65 ; however, its association with @entity454 had not been reported. The aim of the study was to investigate whether @entity454 is a risk factor for @entity2994 , including @entity2994 ( @entity2994 ) and branch @entity2994 (BRVO). This population-based study is based on the longitudinal data from Taiwan National Health Insurance Research Database. The study cohort comprised 5344 @entity1 with diagnosis of @entity454 on hemodialysis or peritoneal dialysis during the period from January 1996 to December 2011. For each @entity454 @entity1 , we selected 20 non- @entity454 @entity1 matched on age and sex. Each @entity454 @entity1 and his/her controls were followed from the initiation of renal dialysis until either the diagnosis of @entity2994 or censorship. Kaplan-Meier method was used to compare the hazard of @entity2994 between cohorts. Stratified Cox proportional hazard models were applied to estimate the hazard ratio (HR) adjusted by the comorbidities of @entity2994 including @entity6 ( @entity6 ), @entity101 , @entity1007 , and @entity2298 . After stratifying by @entity6 status, the statistics were applied again to examine the associations among the @entity6 cohort and non- @entity6 cohort.The 16-year @entity2994 cumulative incidence for @entity454 cohort was 2-fold to the non- @entity454 (1.01% vs 0.46%). After matching with age, sex, @entity101 , and @entity1007 , the adjusted HR was 1.46 (95% confidence interval=1.07-2.01, P value=0.018). By further excluding @entity1 with @entity6 , the adjusted HR escalated to 2.43 (95% confidence interval=1.54-3.83, P<0.001). In contrast, there was no significant risk of @entity454 on @entity2994 in the @entity6 @entity1 (HR=1.03). We conclude that among the non- @entity6 @entity1 , @entity454 cases had significantly higher @entity2994 rate than the non- @entity454 , which indicates that @entity454 maybe a potential risk factor for the development of @entity2994 in nondiabetic @entity1 .
