Thalamic deep brain stimulation in the treatment of essential XXXX .

@entity1 @entity400 @entity2277
BACKGROUND AND PURPOSE: Quality of life can be severely impaired by essential @entity400 (ET) being the main cause of the @entity1 's disability. The authors present a group of ET @entity1 treated with deep brain stimulation of the ventral intermediate nucleus of the thalamus ( @entity2277 DBS). The aim of the study was to evaluate the efficacy and safety of @entity2277 DBS in the treatment of ET. MATERIAL AND METHODS: Between 2006 and 2009, 8 female and 10 male ET @entity1 were treated with @entity2277 DBS. Mean age at implantation was 63    15 years. ET lasted from 4 to 30 years (mean 12 years). Clinical condition of the group was evaluated before surgery and 3 months after implantation with spirography (spiral drawings), the modified Fahn (Tremor Rating Scale, TRS) scale, and the modified ADL (Activity of Daily Living) scale. The @entity2277 was localized with CT and MRI. The procedures of implantation were performed under local and general anaesthesia. A bilateral procedure was performed in 11 cases and a unilateral procedure was performed in 7 cases. RESULTS: The therapeutic effect of DBS was maintained at the follow-up in the third month following surgery. Mean contralateral limb @entity400 reduction was 79%. Head @entity400 reduction was reported by 75% of @entity1 in the bilateral @entity2277 DBS subgroup and 50% of @entity1 in the unilateral @entity2277 DBS subgroup. Mean ADL score improved by 61%. CONCLUSIONS: @entity2277 DBS is a safe and effective method of ET treatment. @entity2277 DBS improves activities of daily living of ET @entity1 .
