Late onset pauciarticular juvenile chronic arthritis: relation to gut XXXX .

@entity1 @entity32 @entity6592 @entity697 @entity625 @entity1530 @entity603 @entity4932 @entity1691 @entity4577 @entity30
Ileocolonoscopy with biopsy of the ileum, ileocecal valve and cecum was performed on 32 @entity1 (22 males, 10 females) with @entity4932 ( @entity4932 ) with pauciarticular onset. Mean age at onset of disease was 12 years. @entity1691 ( @entity1691 ) was diagnosed in 13 @entity1 ; the other 19 cases were classified as @entity625 with recurrent or persistent pauciarticular @entity603 . Twenty-two @entity1 (68%) were @entity1530 positive; 8 @entity1 (25%) carried the HLA-Bw62 antigen. Ileocolonoscopy was performed 6 months to 32 years after the initial manifestation of the disease (mean : 9 years). Fourteen @entity1 had macroscopic lesions of the ileum and ileocecal valve although only 8 of these had a history of intestinal complaints. Twenty-six @entity1 (81%) presented histological signs of gut @entity32 . Most of the gut abnormalities were classified as active @entity30 (19/26). Only 7 @entity1 had acute or @entity4577 . @entity697 were seen in only one @entity1 with @entity1691 . All but 2 @entity1 with @entity6592 , in whom signs of gut @entity32 were found, had active chronic lesions. All the 8 HLA-Bw62 positive @entity1 had histological evidence of gut @entity32 . Only @entity30 were found. In the majority of @entity1 with @entity4932 with pauciarticular onset, gut @entity32 was found on ileum biopsy. Some of their lesions are related to @entity30 , and the presence of the HLA-Bw62 antigen could predispose to the @entity625 seen in these cases.
