RAS mutation-positive follicular variant of XXXX arising in a @entity19967 .

@entity8958 @entity19967 @entity1 @entity3557 @entity1377 @entity5 @entity817 @entity259 @entity44
@entity19967 is an ovarian mature teratoma composed exclusively or predominantly of thyroid tissue. @entity19967 is rare and poorly understood, although this process is thought to be similar to carcinogenesis in @entity5 of differentiated thyroid tissue originating in the thyroid gland. Genetic alterations in the mitogen-activated protein kinase pathway, including mutations of @entity817 , RAS, and @entity8958 genes, have been implicated in the development of @entity259 arising in the thyroid gland. We report here a case with RAS mutation detected in a @entity19967 . The @entity1 is a 38-year-old female who had a 2.4 cm ovarian cyst noted incidentally on a first trimester ultrasound. She proceeded to ovarian cystectomy post-delivery, with pathologic examination detecting a @entity3557 , follicular variant, arising in a @entity44 . The @entity5 was tested for @entity817 , RAS, and @entity8958 /PTC mutations. HRAS codon 61 mutation was identified. This is the first report of RAS mutation detected in the follicular variant of @entity1377 arising in a @entity19967 . It provides evidence that @entity5 developing in this setting involve molecular mechanisms similar to those implicated in @entity5 developing in the thyroid gland.
