Prenatal sonographic ultrasound predictors for the outcome in XXXX : a retrospective analysis.

@entity1 @entity384 @entity6675 @entity2241
PURPOSE: To identify predictive ultrasound signs for unfavorable outcome in @entity2241 ( @entity6675 ). METHODS: This is a retrospective cohort study among pregnant @entity1 with the prenatal diagnosis of @entity6675 between 1998 and 2011 at the University of Wuerzburg, Germany. Analysis included prenatal ultrasound scans, neonatal intensive care unit (NICU) records, and pediatric records. The collected variables included maternal and fetal demographics, as well as an analysis of predictors for unfavorable fetal outcome. Unfavorable outcome was defined by more than 2 postnatal surgical interventions, intestinal resections, and long time to oral feeding (>= 4  weeks). RESULTS: 35 cases of fetal @entity6675 were diagnosed, whereby 23 cases met the inclusion criteria and were evaluated by prenatal ultrasound and postnatal outcome. Based on the postnatal situation, 15 @entity1 were classified in a good prognosis group and 8 @entity1 in a poor prognosis group. Fetuses with poor prognosis were presented later during pregnancy (21.1      6 vs. 26.9      5.3  weeks; p  <  0.01) and delivered at earlier gestational age (35.6      0.8 vs. 33.4      1.4  weeks; p  <  0.01) with lower birth weight (2074      306.3 vs. 2559      255.4  g; p  <  0.01). There were no differences in prenatal findings like growth restriction, amniotic fluid index, or Doppler results between good and poor prognosis group. However, early detected and long-lasting @entity384 was associated with poor prognosis. CONCLUSION: Late presentation and early gestational age at delivery are associated with poor prognosis in neonates with @entity6675 . Furthermore, early onset as well as long duration of @entity384 is associated with poor fetal outcome, while other ultrasound characteristics are not able to predict poor prognosis of @entity6675 .
