Choroidal vascular changes after transpupillary thermotherapy for XXXX .

@entity1 @entity455 @entity5 @entity254 @entity3194 @entity6980 @entity941 @entity320
OBJECTIVE: To evaluate @entity455 after transpupillary thermotherapy used as the sole treatment for @entity320 . DESIGN: Prospective noncomparative interventional case series. @entity1 : Forty-five eyes of 45 @entity1 affected by malignant @entity320 treated with transpupillary thermotherapy alone with more than 1 year of follow-up. INTERVENTION: Transpupillary thermotherapy was performed through a panfunduscopic contact lens using an 810-nm diode laser. MAIN OUTCOME MEASURES: Dynamic/static @entity941 and @entity3194 angiography were performed at scheduled intervals (24 hours, at 3-month intervals during the first year, and every 6 months thereafter) after transpupillary thermotherapy. Visual acuity, clinical evaluation, fundus photographs, and ultrasonographic examination were also performed. RESULTS: The mean follow-up was 30.5 months (range, 12-54 months). Changes in the choroidal circulation were always confined within the treatment margins (except in one case) and characterized by occlusion of choriocapillaris (100%), patent medium and/or large choroidal vessels (76%), @entity254 (11%), and progressive @entity6980 (42%). Forty-one cases (91%) showed persistent clinical regression, and four cases (9%) recurred; recurrent cases showed @entity254 . CONCLUSIONS: Transpupillary thermotherapy is suggested as a new single therapeutic modality in the treatment of selected @entity320 , but more precise eligibility criteria and longer follow-up are mandatory. Patent choroidal circulation, @entity6980 , and @entity254 after transpupillary thermotherapy might be helpful to detect recurrent @entity5 .
