Probiotics affect the clinical inflammatory parameters of experimental @entity2522 in XXXX .

@entity1 @entity32 @entity548 @entity2522 @entity1735
OBJECTIVES: To determine the effects of a probiotic milk drink consumed over a period of 28 days, regarding the expression of clinical inflammatory parameters of the oral gingiva during various phases of plaque-induced @entity2522 . METHODS: Twenty-eight adults with healthy gingiva took part in a prospective and clinical-controlled study. The test group was advised to consume a probiotic milk drink (Yacult) daily during a period of 4 weeks; the control group did not receive any probiotic food or drink. After 2 weeks of consumption of the probiotic drink, @entity1 were advised not to brush their teeth for 14 days. Subsequently, at baseline as well as on days 1, 3, 5, 7 and 14, the following clinical parameters were assessed: plaque index (PI), gingival index (GI), gingival crevicular fluid (GCF) volume and @entity548 on probing (BOP). RESULTS: At baseline, the PI was significantly higher in the test group compared with controls (0.44  0.50 vs 0.09  0.24 PI; P=0.0001). The termination of oral hygiene increased clinical inflammatory parameters in both groups. At day 14, the parameters PI, GI, GCF volume and BOP were significantly higher compared with baseline values (P=0.0001). At day 14, BOP levels (18.75  12.32 vs 36.88  12.54%) and GCF volume (18.78  16.7 vs 35.72  16.1 Periotron units) were significantly lower in the test group compared with the control group (P=0.005). CONCLUSION: The results of our study indicate that a daily consumption of a probiotic milk drink reduces the effects of plaque-induced @entity32 associated with a higher plaque score due to the high- @entity1735 content of the probiotic milk beverage.
