Somatic @entity818 mutation in a @entity977 of a @entity1 with XXXX .

@entity1 @entity511 @entity2695 @entity5 @entity4611 @entity818 @entity8725 @entity977 @entity14051 @entity6446 @entity43180
UNASSIGNED: @entity6446 is a rare disease characterized by @entity6446 and soft-tissue @entity2695 . Additionally, @entity5 including @entity977 have been described in these @entity1 . The underlying genetic etiology lies in somatic mosaicism of mutations in isocitrate dehydrogenase 1 ( @entity818 ) or isocitrate dehydrogenase 2 ( @entity14051 ). This report describes a @entity1 with @entity6446 who presented with @entity5 of the skull base and suprasellar region. The @entity1 underwent resection of both @entity5 , revealing histopathological diagnoses of @entity511 and @entity977 . DNA sequencing of the @entity5 was performed to identify common @entity8725 mutations. Clinical, radiological, and biochemical assessments were performed. Genotypic studies used standard Sanger sequencing in conjunction with a target-specific peptide nucleic acid to detect @entity818 mutations in @entity5 tissues. DNA sequencing demonstrated identical @entity818 mutations ( @entity43180 ) in both @entity5 . To the authors' knowledge, this report provides the first genetic evidence for the inclusion of @entity977 among @entity5 characterizing @entity6446 . In @entity1 who are newly diagnosed with @entity6446 , it is appropriate to monitor for development of @entity4611 .
