Quantitative Susceptibility Mapping of XXXX at Various Stages.

@entity1 @entity3961 @entity1410 @entity6228 @entity1779
PURPOSE: To investigate the magnetic susceptibility of @entity1779 ( @entity1779 ) at various stages by applying @entity6228 ( @entity6228 ). MATERIALS AND METHODS: Blood susceptibility was measured serially using @entity6228 after venous blood withdrawal from healthy subjects. Forty-two @entity1 who provided written consent were recruited in this Institutional Review Board-approved study. Gradient echo magnetic resonance imaging (MRI) data of the 42 @entity1 (17 females; 64        12 years) with @entity1779 were processed with @entity6228 . The susceptibilities of various blood products within @entity1410 were measured on @entity6228 . RESULTS: Blood susceptibility continually increased and reached a plateau 96 hours after venous blood withdrawal. @entity1410 at all stages were consistently hyperintense on @entity6228 . Susceptibility was 0.57        0.48, 1.30        0.33, 1.14        0.46, 0.40        0.13, and 0.71        0.31   ppm for hyperacute, acute, early subacute, late subacute, and chronic stages of @entity1410 , respectively. The susceptibility decrease from early subacute (1.14   ppm) to late subacute (0.4   ppm) was significant (P   <   0.01). CONCLUSION: @entity6228 reveals positive susceptibility in hyperacute @entity1410 , indicating that even at their hyperacute stage, deoxyhemoglobin may exist throughout the @entity1410 volume, not just at its rim, as seen on conventional T2* imaging. @entity6228 also reveals a reduction of susceptibility from early subacute to late subacute @entity1779 , suggesting that @entity3961 concentration decreases at the late subacute stage. J. Magn. Reson. Imaging 2015.
