Prognostic significance of @entity405 + T cell and macrophage peritumoral infiltration in XXXX .

@entity1 @entity1885 @entity5 @entity469 @entity420 @entity14 @entity405
The purpose of this study was to evaluate the prognostic significance of @entity405 + T cell and macrophage peritumoral infiltration in @entity1 with @entity14 . A total of 97 @entity420 of the colon and rectum were examined. Immunohistochemical staining was performed by the standard avidin- @entity1885 -peroxidase complex method using antibodies to @entity405 and @entity469 . Peritumoral infiltration by @entity405 + T cells or macrophages was evaluated along the invasive margin of the @entity5 in each specimen. The area with the most abundant infiltration was selected, and the number of immunoreactive positive cells counted at x400 magnification. @entity1 were divided into two groups based on the degree of infiltration by each cell type: namely those with a high level of infiltration (more than the mean number of positive cells) and those with a low level of infiltration (less than the mean number of positive cells). @entity1 with a low level of macrophage infiltration had a significantly deeper depth of invasion than @entity1 with a high level of macrophage infiltration (P=0.027). The percentage of @entity1 with a high level of macrophage infiltration was significantly higher in vascular invasion-negative cases (46.7%) than in vascular invasion-positive cases (22.7%; P=0.045), and in lymph node metastasis-negative cases (52.9%) than in lymph node metastasis-positive cases (28.3%; P=0.014). Overall survival was significantly shorter for @entity1 with a low level of @entity405 + T cell infiltration than those with a high level of @entity405 + T cell infiltration (P=0.01). The survival rate for @entity1 with a high level of both @entity405 + T cell and macrophage infiltration was 100%. In conclusion, both @entity405 + T cell and macrophage peritumoral infiltration indicates anti-tumoral action in @entity1 with @entity14 .
