Evaluation of febrile XXXX attacks in a tertiary care medical center in @entity233 .

@entity1 @entity981 @entity233 @entity55 @entity221 @entity5898 @entity3052 @entity281 @entity1398 @entity1583 @entity166 @entity4028
BACKGROUND: Infectious complications in febrile @entity1398 @entity1 are still major causes of morbidity and mortality despite significant advances in diagnostic techniques and antimicrobial therapy. In this study, we describe the characteristics of @entity1 with @entity1583 who were evaluated for suspected @entity281 . This study was also conducted to assess the isolation rate of bacterial and fungal causative agents in febrile @entity1398 attacks. METHOD: The study was conducted at Pamukkale University Hospital, @entity233 . In order to identify the characteristics of @entity1 with @entity1583 in the presence/suspicion of any accompanying @entity166 , @entity1 ' charts with @entity1583 were reviewed for signs/symptoms of any @entity281 between October 1, 2001, and May 31, 2005, retrospectively. RESULTS: Overall, 90 @entity166 episodes occurred in 59 @entity1 . The most common underlying diseases were @entity3052 (61.0%) and @entity981 (15.3%). The absolute neutrophil count was lower than 100/mm(3) in 33 (36.7%) episodes. Microbiologically and clinically documented infections and fever of unknown origin were observed in 35.6%, 28.9%, and 35.6% of the @entity1 , respectively. Bloodstream infections and @entity55 were detected in 21.1% and 18.9% of episodes, respectively. Gram negative organisms were most common (58.4%), followed by gram positive cocci. A combination of third generation @entity5898 and an @entity4028 were used in 44.4% of episodes initially. @entity221 resolved in 24.4% of episodes using the initial therapy. The mortality rate was 15.6%. CONCLUSION: These results showed that infections with gram-negative bacteria continue to predominate in febrile neutopenic episodes in our center.
