Body surface area of ST elevation and the presence of late potentials correlate to the inducibility of XXXX in @entity1789 .

@entity1 @entity1789 @entity1164 @entity4128 @entity1165 @entity8655 @entity714 @entity1163 @entity943
INTRODUCTION: The value of noninvasive markers reflecting repolarization and/or conduction abnormalities in identifying @entity1 with abnormal ECG showing a pattern of atypical @entity714 and ST elevation syndrome ( @entity1789 ) at risk for life-threatening @entity943 is controversial. Because right precordial ST elevation reflects inhomogeneous repolarization, we hypothesized that a correlation between the area of ST elevation, that is, the area of inhomogeneous repolarization, and the inducibility of @entity1165 ( @entity1165 ) exists. Therefore, the body surface area of ST elevation and the presence of late potentials were compared to the inducibility of @entity1165 in @entity1 with the characteristic ECG of @entity1789 . METHODS AND RESULTS: A 120-channel body surface potential map was recorded at rest and after administration of a Class I agent ( @entity8655 , 1 mg/kg) to measure the body surface area of ST elevation (> or = 0.2 mV) in 23 individuals (16 @entity1 had been resuscitated from near @entity1164 or had @entity1163 ) with an ECG compatible with the diagnosis of @entity1789 as well as in 15 healthy controls and in 15 @entity1 with @entity4128 . Late potentials were assessed in 20 of the Brugada @entity1 using signal-averaged ECG. Programmed ventricular stimulation was performed at two ventricular sites with up to three extrastimuli. Mean body surface area of ST elevation (> or = 0.2 mV) of all @entity1789 @entity1 was 154 +/- 139 cm2 (control 9 +/- 9 cm2; P < 0.001). In the group of @entity1 with @entity4128 , only one @entity1 was found to have an area of ST elevation (165 cm2). In the presence of ajmaline, area size increased to 330 +/- 223 cm2 in @entity1789 @entity1 (P < 0.05). In @entity1 with inducible sustained (n = 15) and nonsustained @entity1165 (n = 3), a mean area of 183 +/- 139 cm2 was found, whereas the area was only 52 +/- 58 cm2 in those with no @entity1165 induction (P < 0.05). For an area > or = 50 cm2, there were positive and negative predictive values of 92% and 60%, respectively. Positive late potentials were found in 60% of @entity1 and correlated to the inducibility during programmed ventricular stimulation (positive predictive value 100%, negative predictive value 75%; P < 0.001). CONCLUSION: In @entity1 with @entity1789 , the body surface area of ST elevation and the presence of late potentials correlate to the inducibility of @entity1165 during programmed ventricular stimulation and may be of value as a new noninvasive marker for risk stratification in these @entity1 .
