Peripherally inserted central catheter-related vein thrombosis in XXXX @entity1 .

@entity1 @entity0 @entity49 @entity358 @entity3
PURPOSE: To identify clinical incidence, risk factors and treatment of peripherally inserted central venous catheters (PICCs)-related @entity49 ( @entity49 ) in @entity0 @entity1 undergoing chemotherapy. METHODS: We performed a retrospective cohort study of @entity0 @entity1 with PICC insertion undergoing chemotherapy. PICC-related @entity49 was diagnosed by ultrasound. @entity1 -, catheter- and insertion-related factors were analyzed in univariable and multivariable logistic regression to identify significant independent risk factors for PICC-related @entity49 . The incidence and treatment of PICC-related @entity49 were also analyzed. RESULTS: A total of 568 @entity0 @entity1 with PICC undergoing chemotherapy were included, for a total of 54,769 catheter days; 8 @entity1 (1.4%) developed PICC-related @entity49 . The median time of developing @entity49 was 11 days (range of 3 to 79 days). In multivariable analysis, @entity3 (p = 0.002) and malposition (p = 0.013) were shown to be significant risk factors for PICC-related @entity49 . All @entity1 were treated with low-molecular-weight heparin (LMWH) and followed until PICCs were removed. None of the @entity1 developed @entity358 . CONCLUSIONS: @entity3 and malposition were significant risk factors for PICC-related @entity49 in @entity0 @entity1 . With early diagnosis and standardized anticoagulant treatment, a better clinical outcome could be achieved. Further prospective and large sample studies are needed.
