Histopathological yield in different types of bronchoscopic biopsies in proven cases of XXXX .

@entity1 @entity738 @entity1711 @entity1710 @entity378 @entity8638 @entity1907
BACKGROUND: Diagnosis of @entity1907 ( @entity378 ) is difficult and often requires a lung biopsy. The goal of this retrospective study was to determine the histopathological parameters useful for diagnosis of @entity1907 in different types of bronchoscopic biopsies (transbronchial lung biopsy [TBLB], transbronchial needle aspiration [TBNA], and bronchial biopsy [BB]). MATERIALS AND METHODS: The records of @entity1 diagnosed to have @entity1907 , over a period of 1-year were evaluated. @entity1 with positive acid-fast bacilli (AFB) culture and with three bronchoscopic biopsies including TBLB, TBNA, and BB were included in the study. Selected (14) histological parameters were evaluated retrospectively in a total of 27 biopsies from 9 @entity1 with @entity378 after @entity1710 - @entity1711 and Ziehl-Neelsen staining. RESULTS: Diagnostic yield in TBLBs and TBNA was similar for @entity738 detection (66.6% each). @entity738 in TBNA were larger, caseating and confluent as compared to small interstitial @entity738 seen in TBLB. AFB was demonstrated in only one @entity1 in TBNA. Lymphocytic cell cuffing was seen around most TBLB @entity738 . One @entity1 also showed microfilaria in blood vessel in TBLB. BBs in all @entity1 showed the presence of goblet cell metaplasia and increased peribronchial plasma cell infiltrate with or without eosinophils may be indicative of @entity8638 . The yield of @entity738 was low in BBs seen in only 2 @entity1 (22.2%). CONCLUSION: Diagnostic yield of TBNA and TBLB for @entity738 was similar; however, caseation was seen more frequently in TBNA than on TBLB. Of other histological parameters, bronchial metaplastic changes and peribronchial plasma cells infiltrate were constant findings in all tubercular biopsies indicative of @entity8638 .
