Early detection of @entity1370 by 2D and 3D deformation imaging in XXXX receiving chemotherapy.

@entity1 @entity296 @entity1370
The aim of the present study was to find out whether early cardiac changes in @entity1 receiving chemotherapy can be detected by the conventional and deformation parameters of 2D and 3D echocardiography. Twenty-five healthy subjects with normal regional left ventricular function (group 1) and 25 @entity1 receiving chemotherapy (group 2) underwent 2D and 3D transthoracic echocardiography (Toshiba Artida Medical System). All @entity1 (group 2) were examined before and during @entity1370 chemotherapy at a 3-month follow-up. Left ventricular volumes, ejection fraction, muscle mass, global longitudinal, global radial, global circumferential strain, and rotation were analyzed with 2D and 3D echocardiography, while twist and time-to-peak-intervals were analyzed with 3D echocardiography. For left ventricular volumes and muscle mass, no significant differences were seen between the two study groups (P<0.05). According to our results, @entity296 induced by @entity1370 chemotherapy can be detected by 2D global radial strain. Detecting @entity296 by global longitudinal and circumferential strain requires more than 3 months follow-up. Changes in rotation, twist or time-to-peak intervals could not be verified at the 3-month follow-up in the present study. 2D global radial strain seems to be the most sensitive and robust parameter to detect early @entity296 during chemotherapy. 3D echocardiography is not yet an established method to detect @entity296 in clinical practice due to lower spatial and temporal resolution.
