Frameless image-guided radiosurgery for initial treatment of typical XXXX .

@entity1 @entity4254 @entity1183 @entity158
OBJECTIVE: To review retrospectively initial experience at a single institution using frameless image-guided radiosurgery (IGRS) for @entity4254 employing the Novalis linear accelerator (LINAC) with ExacTrac robotic @entity1 positioning device. METHODS: Over an 18-month period, 44 @entity1 (27 @entity1 and 17 @entity1 ; median age 65 years) were treated with frameless IGRS for typical @entity4254 (14 cases involved left-sided @entity158 and 30 cases involved right-sided @entity158 ), responsive to anticonvulsant medications, with Barrow Neurological Institute @entity158 Scale (BNI-PS) scores of 4 or 5. All cases were initial radiosurgery treatments with an isocenter dose of 90 Gy delivered via a 4-mm circular collimator forming a spheroid dose envelope. Intrafraction positioning data were collected for all @entity1 . The median follow-up was 15 months. RESULTS: Overall intrafraction positioning error was 0.49 mm    0.44. After treatment, 40 @entity1 achieved a BNI-PS score of IIIb or better; 19 @entity1 achieved a BNI-PS score of I. The median time to @entity158 relief was 4 weeks. Overall, new @entity1183 was seen in five @entity1 . No other complications were seen. CONCLUSIONS: Use of frameless IGRS methods for treatment of @entity4254 showed results similar to the authors' prior experience with frame-based treatment methods. IGRS using frameless methods is a suitable treatment method for @entity1 with @entity4254 and may be applicable to other functional indications.
