May the neutrophil/lymphocyte ratio be a predictor in the differentiation of different XXXX ?

@entity3557 @entity32 @entity1 @entity5 @entity1669 @entity1376 @entity259 @entity1374
BACKGROUND: The neutrophil/lymphocyte ratio (NLR) is a simple index of systemic inflammatory response, and has been shown to be a prognostic indicator in some types of @entity5 . @entity32 has been implicated in the initiation and progression of @entity259 . The aim of this study was to examine the relationship of NLR with @entity3557 ( @entity3557 ) and different benign thyroid pathologies like @entity1376 ( @entity1376 ) and @entity1669 ( @entity1669 ). MATERIALS AND METHODS: We retrospectively evaluated the neutrophil, lymphocyte counts and NLR calculated from these parameters of 232 @entity1 with histologically confirmed as @entity1376 (group @entity1376 ) (n=70), @entity1669 (group @entity1669 ) (n=97), @entity1669 with @entity3557 (group @entity1669 - @entity3557 ) (n=25) and @entity3557 (group @entity3557 ) (n=40). The optimal cut-off value for NLR was determined. RESULTS: NLR level was significantly higher in groups @entity1669 - @entity3557 and @entity3557 as compared to groups @entity1376 and @entity1669 (p<0.05). NLR of @entity1669 subgroups according to TSH levels were not different (p>0.05). When we grouped the @entity1 as benign and malignant according to @entity3557 presence, the optimum NLR cut-off point obtained from ROC analysis was 1.91 (sensitivity 89.0% and specificity 54.5%). CONCLUSIONS: Since NLR was significantly elevated in group @entity1669 - @entity3557 and group @entity3557 , NLR value may give an opinion as a potential marker in differentiation of benign and @entity1374 . For this purpose a cut-off value of 1.91 for NLR may be accepted.
