Limited external irradiation and interstitial 192iridium implant in the treatment of XXXX of the tonsillar region.

@entity1 @entity3329 @entity39 @entity5 @entity957 @entity7190
Between January 1976 and March 1982, 80 @entity1 with histologically proven diagnosis of @entity957 of the tonsillar region were treated with definitive radiotherapy. Sixty-five (81%) of these @entity1 had locally advanced @entity5 (Stage III and IV); 49% of @entity1 had clinically palpable cervical @entity3329 . All @entity1 received a combined external megavoltage and interstitial irradiation. The dose of external irradiation was limited to 4500-5000 cGy over 41/2 to 51/2 weeks. This was followed by interstitial 192iridium implants to doses of 2000-2500 cGy in 50-60 hours for T1, T2 lesions and 3000-4000 cGy in 60-100 hours for T3 , T4 lesions. The neck masses were also separately implanted to deliver additional doses of 2000-4000 cGy in 50-80 hours. Overall @entity5 control was observed in 84% of @entity1 with a minimum follow-up period of 2 years. An absolute 3-year disease free survival of the entire group was 72%. Treatment related complications such as soft tissue @entity39 or @entity7190 occurred in 6% (5/80) of @entity1 . The salvage of neck failures and local failures was possible in 78 and 38% of @entity1 , respectively, either by surgery or by re-irradiation employing interstitial 192iridium implants. Functional and esthetic integrity was well preserved in most cases.
