Genetic identification and risk factor analysis of asymptomatic bacterial colonization on XXXX .

@entity1 @entity5938 @entity794 @entity2348 @entity177 @entity281 @entity2259 @entity65 @entity922 @entity884
Asymptomatic bacterial colonization of @entity65 ( @entity65 ) is widespread and increases the risk of clinical @entity281 . The aim of the study was to evaluate the incidence of bacterial colonization of generator pockets in @entity1 without signs of @entity281 and to analyze the relationship with @entity922 and risk factors. From June 2011 to December 2012, 78 @entity1 underwent CIED replacement or upgrade. Exclusion criteria included a clinical diagnosis of @entity281 , @entity2259 , or @entity884 . All @entity1 were examined for evidence of bacterial 16S rDNA on the device and in the surrounding tissues. Infection cases were recorded during follow-up. The bacterial-positive rate was 38.5% (30 cases); the coagulase-negative @entity794 detection rate was the highest (9 cases, 11.5%). Positive bacterial DNA results were obtained from pocket tissue in 23.1% of @entity1 (18 cases), and bacterial DNA was detected on the device in 29.5% of @entity1 (23 cases). During follow-up (median 24.6 months), two @entity1 (6.7%, 2/30) became symptomatic with the same species of microorganism, @entity794 and @entity5938 . Multivariable logistic regression analysis found that the history of @entity2348 , use of antibiotics, application of antiplatelet drugs, replacement frequency, and @entity177 were independent risk factors for asymptomatic bacterial colonization.
