The effect of XXXX or thiamylal on @entity2900 -induced myoglobinemia under @entity1508 anesthesia in adults.

@entity1 @entity1508 @entity908 @entity26 @entity3652 @entity3810 @entity972 @entity5632 @entity2900
We studied the effect of intravenous (IV) thiamylal or @entity3652 on the increases in serum @entity5632 , @entity908 kinase (CK), and @entity972 induced by @entity2900 under @entity1508 anesthesia. Ninety @entity1 were divided into three groups. In Group O, @entity2900 (1.0 mg/kg) was administered after an the inhaled induction of anesthesia with @entity1508 . In Group T, thiamylal (4.0-5.0 mg/kg), and in Group K, @entity3652 (1.5-2.0 mg/kg) was injected prior to @entity2900 administration. Anesthesia was maintained with @entity1508 , @entity3810 , and @entity26 . @entity5632 increased in Group O at 60 min to 855 ng/mL (median) and CK to 98.6 IU/L. These increases were significantly higher than those of Group T (110 ng/mL and 66.4 IU/L) and Group K (110 ng/mL and 57.0 IU/L). @entity972 increased in Group O only. There was no significant difference between Groups T and K for any of the three values. These results indicate that IV thiamylal and @entity3652 both suppress the increases of @entity5632 , CK, and @entity972 , and that in cases when @entity2900 is used, both drugs can help to avoid myoglobinemia and limit the increases of CK and @entity972 .
