[ XXXX chemotherapy for @entity356 ].

@entity1 @entity5 @entity75 @entity2592 @entity1139 @entity1500 @entity356 @entity1487
@entity5 chemotherapy for @entity356 was reviewed with special emphasis on histologic findings and survival. Preoperative chemotherapy with intravenous, split administration of @entity1139 40 mg caused considerable damage to "micro-solitary metastatic foci" in metastatic lymph nodes. In view of the lipid-adsorbing ability of the lymphatic stream, emulsified @entity1487 was used orally in 182 @entity1 with @entity356 ; histologic findings revealed that the emulsified @entity1487 enhanced the antitumor efficacy for metastatic lymph nodes as well as the @entity75 . However, the 5-year survival rate for @entity356 @entity1 undergoing preoperative emulsified @entity1487 therapy did not differ from the control, with only the exception of @entity1 with @entity5 . On the other hand, combined therapy involving preoperative intra-arterial infusion and surgery was carried out in 62 @entity1 with @entity356 . These preoperative treatments using @entity1139 , @entity1487 , VLB, @entity1500 and/or @entity2592 entailed continuous infusion for 15 to 20 hours; the histologic changes observed revealed marked antitumor effects on the primary focus as well as metastatic lymph nodes. The five-year survival rate for the 62 @entity1 was compared with that for 99 @entity1 with @entity356 in the corresponding period. The survival rate was analyzed based on the degree of serosal invasion. The overall survivals in the 62 @entity1 were higher than those in the controls for the first 3 years. At 4 to 5 years, the survival rates for both the treated and control groups were approximately equal. In @entity1 without serosal invasion, the survival rates were higher in treated cases than in the controls for the first 2 years. Thirty-nine @entity1 with serosal invasion had significantly higher survival rates than the controls for the first 3 years. The survival rates for the treated @entity1 with cancerous infiltration of ther organs were about the same as those for the corresponding control @entity1 .
