Non-fatal cardiovascular outcome in @entity1 with posttraumatic stress symptoms caused by XXXX .

@entity1 @entity301 @entity1005 @entity583 @entity943 @entity65
OBJECTIVES: @entity1005 ( @entity1005 ) prospectively increases the risk of incident @entity65 ( @entity65 ) independent of other risk factors in otherwise healthy individuals. Between 10% and 20% of @entity1 develop @entity1005 related to the traumatic experience of @entity583 ( @entity583 ). We investigated the hypothesis that @entity1005 symptoms caused by @entity583 predict adverse cardiovascular outcome. METHODS: We studied 297 @entity1 (61    10 years, 83% @entity1 ) who self-rated @entity1005 symptoms attributable to a previous index @entity583 . Non-fatal @entity65 -related hospital readmissions (i.e. recurrent @entity583 , elective and non-elective intracoronary stenting, bypass surgery, pacemaker implantation, @entity943 , cerebrovascular event) were assessed at follow-up. Cox proportional hazard models controlled for demographic factors, @entity301 severity, major @entity65 risk factors, cardiac medication, and mental health treatment. RESULTS: Forty-three @entity1 (14.5%) experienced an adverse event during a mean follow-up of 2.8 years (range 1.3-3.8). A 10 point higher level in the @entity1005 symptom score (mean 8.8    9.0, range 0-47) revealed a hazard ratio (HR) of 1.42 (95% CI 1.07-1.88) for a @entity65 -related hospital readmission in the fully adjusted model. A similarly increased risk (HR 1.45, 95% CI 1.07-1.97) emerged for @entity1 with a major or unscheduled @entity65 -related readmission (i.e. when excluding @entity1 with elective stenting). CONCLUSIONS: Elevated levels of @entity1005 symptoms caused by @entity583 may adversely impact non-fatal cardiovascular outcome in post- @entity583 @entity1 independent of other important prognostic factors. The possible importance of @entity1005 symptoms as a novel prognostic psychosocial risk factor in post- @entity583 @entity1 warrants further study.
