Predictors of clinically significant postoperative events after XXXX surgery.

@entity1 @entity137 @entity927 @entity91 @entity3816
BACKGROUND: @entity91 surgery is associated with clinically significant postoperative events requiring intensive care unit (ICU) admission. The authors investigate specific variables, which might influence the risk for these events, and thereby make recommendations regarding the need for postoperative ICU admission. METHODS: A retrospective review of 225 @entity1 undergoing @entity91 repair at a single center during a 10-yr period is reported. The primary outcome measure was the incidence of predefined clinically relevant postoperative cardiorespiratory and hematological events requiring ICU admission. RESULTS: The incidences of postoperative cardiorespiratory and hematological events requiring ICU care were 14.7% (95% CI, 10.5 to 20.1%) and 29.7% (95% CI, 24.0 to 36.3%), respectively. Independent predictors of @entity137 were body weight less than 10   kg, American Society of Anesthesiologists physical status 3 or 4, intraoperative transfusion of greater than 60   ml/kg packed erythrocytes, and the occurrence of an @entity3816 . The independent predictors of hematological events were body weight less than 10   kg, American Society of Anesthesiologists physical status 3 or 4, intraoperative transfusion of greater than 60   ml/kg packed erythrocytes, transfusion of hemostatic products (fresh-frozen plasma, platelets, and/or cryoprecipitate), and @entity927 not administered. CONCLUSIONS: @entity1 undergoing @entity91 surgery are at increased risk for clinically significant postoperative events requiring ICU admission if they are less than 10   kg body weight, American Society of Anesthesiologists physical status 3 or 4, require intraoperative transfusion of greater than 60   ml/kg of packed erythrocytes, receive hemostatic blood products, or if they develop a significant @entity3816 . @entity927 administration was associated with fewer postoperative events. A predictive clinical algorithm for pediatric @entity1 having major @entity91 surgery was developed and validated to risk stratify these @entity1 .
