Feasibility of assessment of conjunctival microvascular hemodynamics in unilateral XXXX .

@entity735 @entity64 @entity385
Since the internal carotid artery supplies blood to both the eye and the brain, ocular microvascular hemodynamics can be altered due to @entity385 . The purpose of the current study was to establish the feasibility of conjunctival microcirculation imaging for detection of inter-ocular differences in microvascular hemodynamics in subjects with unilateral @entity385 . Conjunctival microcirculation imaging was performed in both eyes of 15 healthy control subjects and 12 subjects following unilateral @entity385 . Diameter and axial blood velocity were measured in multiple conjunctival venules of each eye. A two-way repeated measures analysis of variance was performed to determine the effects of @entity64 (control vs. @entity64 ) and side of @entity64 (ipsilateral vs. contralateral) on conjunctival diameter and axial blood velocity. There was no significant main effect of @entity64 on conjunctival diameter (P=0.7) or conjunctival axial blood velocity (P=0.9). There was no significant main effect of side of @entity64 on conjunctival diameter (P=0.8), but there was a significant main effect of side of @entity64 on conjunctival axial blood velocity (P=0.02). There was a significant interaction effect between @entity64 and side of @entity64 (P=0.04), indicating that conjunctival axial blood velocity was @entity735 than in contralateral eyes of @entity64 subjects. Conjunctival axial blood velocity and internal carotid artery blood velocity were correlated in @entity64 subjects (r=0.75, P=0.01, N=10). Conjunctival microcirculation imaging is a feasible method to detect inter-ocular differences in microvascular hemodynamics in subjects with unilateral @entity385 .
