Photorefractive keratectomy versus laser in situ keratomileusis for the treatment of spherical XXXX .

@entity1 @entity3467 @entity282 @entity158
OBJECTIVE: To compare photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) in treating spherical @entity3467 using the VISX STAR S2 excimer laser. INTERVENTION: Fifteen consecutive eyes of 15 @entity1 underwent PRK, and 16 consecutive eyes of 16 @entity1 underwent LASIK (follow-up: 12 months). MAIN OUTCOME MEASURES: @entity282 , uncorrected visual acuity (UCVA), deviation from intended correction, and loss of best spectacle-corrected visual acuity (BSCVA). RESULTS: Mean preoperative spherical equivalent was + 2.18 diopter [D] for PRK and + 2.03D for LASIK. All PRK @entity1 experienced significant @entity282 that required systemic medication, whereas LASIK @entity1 had minor and transient discomfort. Mean deviation from intended correction was -0.83D, + 0.01D, and + 0.18D at 1, 6, and 12 months after PRK, and + 0.22D, +0.30D, and + 0.40D at 1, 6, and 12 months after LASIK (P = 0.002 at 1 month). A higher proportion of LASIK eyes had a UCVA of 20/20 or better at all time points (P = 0.013 and 0.025 at 1 and 3 months, respectively). There was no statistically significant difference between both groups in BSCVA loss. CONCLUSIONS: LASIK and PRK are comparable in efficacy and safety. However, PRK was more @entity158 , with an initial and temporary myopic over-correction that did not occur after LASIK. Stability was achieved between 3 and 6 months following PRK, and one month following LASIK.
