Factors predicting concurrent XXXX associated with hepatolithiasis.

@entity1 @entity353 @entity5 @entity648 @entity787 @entity201 @entity490 @entity99 @entity255
BACKGROUND/AIMS: Hepatolithiasis is a risk factor for @entity201 . However, it is difficult to detect early @entity201 that occurs as a complication of hepatolithiasis. To identify the factors, which can be used for predicting @entity201 in @entity1 with hepatolithiasis, we compared the clinical characteristics of @entity1 who had @entity201 associated with hepatolithiasis with those of @entity1 with hepatolithiasis only. METHODOLOGY: Forty @entity1 with @entity201 associated with hepatolithiasis (group HC) and 73 @entity1 with hepatolithiasis only (group H) were randomly selected for this study. Mean @entity5 size was 6.1 +/- 2.4 cm in diameter. RESULTS: @entity1 of group HC were older (56.7 +/- 8.9 yr) than those of group H (49.2 +/- 12.9 yr) (p < 0.001). Weight loss was more frequent in group HC (51.5%) than in group H (5.5%) (p < 0.001) and serum alkaline phosphatase levels were higher in group HC (181 +/- 184 IU/L) than in group H (426 +/- 385 IU/L) (p < 0.001). The proportion of the @entity1 who had hepatolithiasis in the right or both lobes of the liver was higher in group HC (72.5%) than in group H (50.6%) (p = 0.024). The optimal cutoff value of serum @entity787 level for @entity201 detection was set at 4.2 ng/mL using ROC cure to give a sensitivity of 67.6% and a specificity of 90.5%. Group HC differed from group H because of its lower rates of both @entity490 and @entity255 , longer duration of stone history, and lower serum albumin level. Factors that did not predict @entity201 included sex ratio, white blood cell count, serum @entity648 level, and @entity99 . CONCLUSIONS: @entity201 should be suspected in @entity1 with hepatolithiasis, especially when, the @entity1 is over 40 years old, has a long history of hepatolithiasis with @entity353 , a higher level of serum alkaline phosphatase, a lower level of serum albumin, a serum carcinoembryonic antigen level exceeding 4.2 ng/mL, and hepatolithiasis that is located either in the right or both lobes of the liver.
