Upper Normal XXXX Aminotransferase Range and @entity2690 Resistance in Korean Adolescents: Korean National Health and Nutrition Examination Survey, 2009-2010.

@entity1 @entity1560 @entity409 @entity2690 @entity3929 @entity209
BACKGROUND: @entity3929 aminotransferase (ALT) has been one of the most useful biomarkers reflecting @entity409 . Some studies have proposed that serum ALT levels, even those within the conventional normal range, are associated with @entity209 and @entity1560 . AIMS: We examined the correlation between ALT levels and @entity2690 resistance (IR) and ALT cutoff value for high IR status in Korean adolescents. METHODS: A total of 886 subjects (461 @entity1 and 425 @entity1 ) who participated in the 2009-2010 Korea National Health and Nutrition Examination Survey were included in this study. Multivariable adjusted logistic regression analyses were used to examine the odds ratios and 95  % confidence intervals (CIs) of the prevalence of the highest quartile of the homeostasis model assessment of IR (HOMA-IR) according to the ALT quartile. The cutoff value of ALT for the highest HOMA-IR quartile (Q4) were obtained using receiver operating characteristic curve analysis. RESULTS: The mean ALT value increased as the number of @entity209 components increased, but in only @entity1 (p for trend <0.001), while the IR quartile increased in both @entity1 and @entity1 (all p for trends <0.001). The prevalence of IR (Q4) was only increased in ALT (Q4) in @entity1 after the adjustment for age, body mass index, and waist circumference (OR 2.49; 95  % CI 1.05-5.91; p for trend  =  0.017). The cutoff values were 17.0  IU/L in @entity1 and 11.0  IU/L in @entity1 . CONCLUSIONS: The highest ALT quartile was associated with an increased prevalence of the highest quartile of IR in @entity1 but not in @entity1 .
