Racial differences in initial treatment for clinically localized XXXX . Results from the @entity263 outcomes study.

@entity1 @entity7735 @entity263 @entity146 @entity5
OBJECTIVE: We examined whether there were racial differences in initial treatment for clinically localized @entity263 and investigated whether demographic, socioeconomic, clinical, or @entity5 characteristics could explain any racial differences. DESIGN: Prospective cohort study. SETTING: Population-based @entity5 registries in Connecticut, Los Angeles, and Atlanta. @entity1 : We evaluated 1144 African-American and non-Hispanic white @entity1 , aged 50 to 74 years, with clinically localized @entity5 diagnosed between October 1994 and October 1995. MEASUREMENTS AND MAIN RESULTS: We obtained demographic, socioeconomic, and clinical data from @entity1 surveys and medical record abstractions. We reported adjusted percentages for receiving treatment derived from multinomial logistic regression. We found an interaction between race and @entity146 . Among @entity1 with @entity5 ( @entity7735 > or = 20 ng/mL or Gleason score > or = 8), African Americans were less likely to undergo radical prostatectomy than non-Hispanic whites (35.2% vs 52.0%), but more likely to receive conservative management (38.9% vs 16.3%, P=.003). Among the 71% of subjects with @entity5 , African Americans and non-Hispanic whites were equally likely to receive either radical prostatectomy or radiation therapy (80.0% vs 84.5%, P=.2). CONCLUSIONS: African Americans with @entity5 were less likely to undergo radical prostatectomy and more likely to be treated conservatively. These treatment differences may reflect African Americans' greater likelihood for presenting with pathologically advanced @entity5 for which surgery has limited effectiveness. Among @entity1 with @entity5 -the majority of cases-there were no racial differences in undergoing radical prostatectomy or radiation therapy.
