Treatment outcome of XXXX with carbon dioxide laser--emphasis on the factors affecting recurrence.

@entity1 @entity8407 @entity1082 @entity12120 @entity1141
PURPOSE: To evaluate the associated factors of recurrence in @entity1 who received laser surgery for @entity8407 . MATERIALS AND METHODS: Clinicopathologic data of @entity1 and their @entity1082 genome status were used to analyze their association with recurrence after surgery. RESULTS: Of 114 enrolled @entity1 , 90 were @entity1 and 24 were @entity1 with an average age of 49.7    12.2 years, and follow-up was 1.75 to 9.1 years (mean, 3.4    1.3 years). Recurrence after surgery occurred in 20 @entity1 (17.5%). Thirteen @entity1 had malignant transformation (11.4%). Twenty @entity1 showed positivity for @entity1082 (21.7%). Univariate analysis showed that @entity1 who did not quit smoking or chewing betel quid after surgical treatment or whose @entity8407 took the form of widespread multiple-focus lesions, nonhomogeneous @entity12120 , and higher-grade @entity1141 tended to have recurrence. Among these significant risk factors, continuous smoking after surgical treatment (odds ratio, 3.82) and widespread multiple-focus lesions (odds ratio, 4.54) were the independent prognostic factors for recurrence using multivariate logistic regression analysis. Those who did not quit chewing betel quid or smoking cigarettes were 19.8 or 9.7 times, respectively, more likely to develop recurrence than those who did quit. CONCLUSIONS: This study suggests that continuous smoking after surgical treatment and widespread multiple-focus lesions are the prognostic indicators for recurrence after laser surgery. Changes in oral habits can be of great importance to the outcome of laser surgery of @entity8407 .
