XXXX in the uremic @entity35 .

@entity1 @entity1944 @entity72185 @entity30444 @entity5507 @entity1674 @entity177 @entity72186 @entity35
In the past we have shown that @entity1 with @entity177 ( @entity177 ) on hemodialysis show evidence of @entity1944 of fat. The present study was designed to verify this finding in an animal model. Male @entity35 weighing +/- 200 g were studied. @entity5507 ( @entity5507 ) was induced by 2-stage subtotal (5/6) nephrectomy. Control (C) animals were sham-operated. Fat absorption was studied after 6 weeks of @entity5507 with the oral fat loading test. Twenty percent intralipid (0.25 g/100 gBW) was given by gastric tube feeding to fasting animals and the appearance of chylomicrons (CHYL) and the rise of @entity1674 (TG) in the serum was followed for 5 hrs. In order to isolate the effect of fat absorption, an additional group of @entity5507 and C animals was pretreated with @entity30444 and triton, thus blocking hepatic TG synthesis and neutralizing peripheral lipoprotein lipase activity. The absorption of CHYL was significantly (p less than 0.01) impaired in all @entity5507 animals and averaged 43 and 70 percent of that of the C animals, 1 and 2 hrs after the load respectively. The rise in serum TG did not differ from C in mildly @entity5507 animals (Scr 1.0 +/- 0.04). In the more severely uremic animals (Scr 2.6 +/- 0.2), however, pretreated with @entity30444 and triton, the rise in serum TG was far less (p less than 0.01) than in C animals (111 +/- 26-903 +/- @entity72185 % V.780 +/- 170-5032 +/- @entity72186 %) 1 and 5 hrs after the load.(ABSTRACT TRUNCATED AT 250 WORDS)
