Bacille Calmette-Gu  rin XXXX .

@entity1 @entity738 @entity39 @entity75 @entity4034 @entity79 @entity733 @entity158 @entity378 @entity291
BACKGROUND: @entity378 is an essential problem for healthcare systems especially in developing countries. All newborns are given Bacillus Calmette-Gu  rin (BCG) vaccine in Iran which is prepared from live @entity291 @entity378 bacillus, and is given to protect against @entity378 . @entity4034 secondary to BCG vaccination is rare and usually involves epiphysis of long tubular bones. METHODS: 4 @entity1 , 3 males and a female entered this study and were between 11 to 24 months old. The involved bones were first metatarsi, talus, humerus and tibia bone. The main radiologic finding was @entity75 with cortical destruction and periosteal reaction. RESULTS: 3 @entity1 underwent core needle biopsy and the one with the proximal tibia involvement, underwent open surgery. Pathology report suggested @entity738 and @entity39 compatible with @entity378 . Surgical treatment for these @entity1 was curettage and debridement of the @entity79 and involved tissues around. The @entity1 got standard anti TB pharmacotherapy, were completely cured and no short term complication was seen in a one year follow up. CONCLUSION: BCG @entity4034 and @entity733 , should be kept in mind when assessing a @entity1 presenting chronic symptoms like @entity158 , limping or local swelling of extremities. The long interval time between BCG vaccination and outbreak of the culture-negative abscess is a major point which emphasizes on pathologic evaluation. Image guided tissue biopsy and PCR studies confirm diagnosis. Early use of a surgical curettage and debridement along with chemotherapy soon afterwards, enabled these @entity1 to enjoy a satisfactory clinical outcome.
