Muscle metabolism in XXXX studied by @entity15340 magnetic resonance spectroscopy during aerobic and anaerobic exercise.

@entity1 @entity239 @entity26 @entity1391 @entity158 @entity15340
OBJECTIVE: To investigate mechanisms underlying the reduced work capacity of @entity239 ( @entity239 ) @entity1 were compared to healthy controls at specified workloads, using @entity15340 magnetic resonance spectroscopy (MRS). METHODS: The forearm flexor muscle group was examined with MRS at rest, at sub maximal and at maximal controlled dynamic work as well as at maximal isometric contraction. Aerobic fitness was determined by bicycle ergonometry. RESULTS: Metabolite concentrations and muscle pH were similar for @entity1 and controls at lower workloads. At maximal dynamic and static contractions the concentration of inorganic @entity1391 was lower and at static contractions the pH decrease was smaller in @entity1 . The performed work by @entity1 was only 50% compared to controls and the @entity1 experienced more @entity158 . Maximal @entity26 uptake was lower in the @entity239 group. Expired gas-analysis in this group showed ventilatory equivalents at similar relative levels of maximal work capacity. CONCLUSION: @entity239 @entity1 seem to utilise less of the energy rich phosphorous metabolites at maximal work despite pH reduction. They seemed to be less aerobic fitted and reached the anaerobic threshold earlier than the controls.
