[Nine cases of XXXX predominantly affecting the lower lung fields].

@entity1 @entity1143 @entity82 @entity1289 @entity850 @entity3217 @entity1353 @entity2416 @entity358 @entity4595 @entity2355 @entity401 @entity370 @entity10070
OBJECTIVES: @entity10070 which predominantly affects the lower lung fields is relatively rare. We performed this study to clarify the clinical manifestations of this type of @entity370 . SUBJECTS AND METHODS: Over a period of 13 years, we diagnosed @entity10070 in 119 @entity1 . Among these, we reviewed the clinical characteristics of 9 @entity1 (3 @entity1 , 6 @entity1 , mean age 62 years) with @entity358 predominantly affecting the lower lung fields. RESULTS: Four @entity1 had a history of dust inhalation and 6 had symptoms of @entity1353 . All @entity1 had @entity3217 and 5 had cutaneous lesions. Serum @entity2355 levels were elevated in all @entity1 , whereas @entity1289 ( @entity1289 ) levels were elevated in 3. Pulmonary function tests revealed @entity850 in 4 @entity1 , and decreased diffusion capacity in 7. Chest CT findings in the lower lung fields revealed bronchovascular thickening, micronodular opacities in the vessels and chest wall, and interlobular septal thickening in 8 @entity1 ; ground-glass opacities in 5; curvilinear shadows in 4; and patchy shadows, traction @entity4595 , and @entity1143 in 3. Histopathologic findings of lung biopsy specimens featured granulomas in all @entity1 , and pulmonary interstitium @entity82 and small round-cell infiltration in the alveoli of most @entity1 . CONCLUSION: @entity1 with @entity370 affecting the lower lung fields often had symptoms of @entity1353 , extrapulmonary lesions in the eye and/or on the skin, and elevated serum @entity2355 levels but not @entity1289 . Chest CT showed findings typical of @entity370 , such as lymphatic distribution, but also showed unusual findings such as ground-glass opacities, curvilinear shadows, patchy shadows, traction @entity4595 and @entity1143 . We speculated that 1 @entity1 with ground-glass opacities and traction @entity4595 without lymphatic distribution on CT, and fibroblastic foci with @entity2416 histopathologically, had complications of a different type of @entity401 .
