XXXX : clinical and muscle biopsy findings.

@entity1 @entity14629 @entity8482 @entity3986 @entity1159 @entity2057 @entity121
Thirteen cases of @entity8482 without evidence of @entity2057 , @entity3986 , or structural @entity121 were reviewed. Family history, consanguinity, pregnancy, delivery, number and severity of @entity1159 , and outcome were evaluated. Laboratory investigations had been performed and a biopsy of muscle from an affected limb had been examined histochemically and by electron microscopy. Five biopsies showed fiber type 1 predominance and three had type 2 predominance. Patterns of fiber-type predominance may have resulted from altered neural influence leading to impaired maturation of type 1 or 2 motor units. Nine @entity1 had been followed up for 3-8 years. Two were still not walking at age 8 years. For the 6 who were walking, the mean age at ambulation was 4.7 years. There was no deterioration in power. Muscle biopsy is recommended in @entity8482 . Identification of a probable @entity14629 is important because the condition is not progressive and is apparently not transmitted genetically.
