Feather bedding and childhood @entity565 associated with XXXX sensitisation: a randomised controlled trial.

@entity1 @entity4186 @entity565 @entity432 @entity6711 @entity25
INTRODUCTION: Observational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and @entity565 symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure. OBJECTIVE: To determine whether, among @entity1 not using feather upper bedding, a new feather pillow and feather quilt reduces @entity565 severity among @entity6711 ( @entity6711 ) sensitised @entity1 with @entity565 over a 1-year period compared with standard dust mite avoidance advice, and giving @entity1 a new @entity432 cover. DESIGN: RCT. SETTING: The Calvary Hospital in the Australian Capital Territory and the @entity1 's Hospital at Westmead, Sydney, New South Wales. @entity1 : 197 @entity1 with @entity6711 sensitisation and moderate to severe @entity565 . Intervention New upper bedding @entity4186 feather pillow and quilt and a @entity432 cover (feather) versus standard care and a @entity432 cover (standard). MAIN OUTCOME MEASURES: The proportion of @entity1 reporting four or more episodes of wheeze in the past year; an episode of speech-limiting wheeze; or one or more episodes of @entity25 caused by wheezing; and spirometry with challenge testing. Statistical analysis included multiple logistic and linear regression. RESULTS: No differences between groups were found for primary end points--frequent wheeze (OR 1.51, 95% CI 0.83 to 2.76, p=0.17), speech-limiting wheeze (OR 0.70, 95% CI 0.32 to 1.48, p=0.35), sleep disturbed because of wheezing (OR 1.17, 95% CI 0.64 to 2.13, p=0.61) or for any secondary end points. Secondary analyses indicated the intervention reduced the risk of sleep being disturbed because of wheezing and severe wheeze to a greater extent for @entity1 who slept supine. CONCLUSION: No differences in respiratory symptoms or lung function were observed 1 year after @entity1 with moderate-severe @entity565 and @entity6711 sensitisation were given a @entity432 cover and then received either feather upper bedding (pillow and quilt) or standard bedding care.
