Increased @entity908 kinase and spontaneous activity on electromyography, in XXXX .

@entity1 @entity908 @entity4681 @entity746 @entity2901
INTRODUCTION: Mild to moderate elevation of muscle @entity908 kinase (CK) is commonly observed in @entity746 ( @entity746 ). Although the determinants of increased the CK in @entity746 remain uncertain, we hypothesize that @entity2901 and muscle denervation can be involved by damaging the muscle fibre. @entity1 AND METHODS: We studied 87 @entity746 @entity1 in whom CK determination was performed. In 47, a standardized EMG investigation was performed. In 22 @entity1 a second CK determination was performed a mean of 5 months later. CK values were compared between different @entity1 arranged in groups as determined by the number of regions with @entity2901 as detected on the clinical examination, and the number of muscles with @entity2901 or with fibrillation potentials as observed on EMG. RESULTS: 43% of our population had an increased CK value. Four out of 5 @entity1 with suspected @entity746 had an increased CK value. The number of @entity1 with increased CK value was not different between sexes, or between bulbar and spinal-onset @entity1 . CK value was not related with disease duration, and did not change at the second measurement. CK value was not different between the groups studied. CONCLUSION: The @entity2901 ,and the signs of denervation on EMG, are not determinants for high CK values in @entity746 @entity1 , which are still unknown. Increased CK can be useful in the differential diagnosis of @entity1 with @entity4681 .
