[Effect of cis-platinum in XXXX ].

@entity1 @entity8 @entity4295 @entity409 @entity1726 @entity521 @entity1011 @entity236 @entity7397 @entity1209
We treated six @entity1 with @entity521 . They were all refractory to conventional chemotherapy or at an advanced stage when diagnosed. @entity1 were four males and two females aged 1 to 7 years old, with a mean age of 3.7 years. Total @entity7397 dose ranged from 60 mg/m2 to 720 mg/m2, with a median dose of 240 mg/m2, and a mean dose of 260 mg/m2. Of the six @entity1 , two were PR, three were @entity1726 , and one was NC. Of three non-responses, two cases were clinically improved. Two cases had @entity8 but this improved within 3 weeks. It is said that @entity7397 induces irreversible @entity8 , especially @entity4295 . Our two cases had progressively decreased @entity1011 clearance, though values of BUN and @entity1011 were normal. @entity236 was mild, so there was no need to discontinue or modify the @entity7397 chemotherapy schedules. Two hypo-magnesemia were found, both cases being asymptomatic. Transient @entity409 occurred in one @entity1 , and @entity1209 were observed in almost all cases.
