Role of oxidative stress and serum lipid levels in stable XXXX .

@entity1 @entity32 @entity66 @entity63 @entity1674 @entity519 @entity1030 @entity165
BACKGROUND: @entity1030 ( @entity1030 ) has been associated with increased oxidative stress or reduced antioxidant resources. The main goal of this study was to evaluate the levels of serum @entity63 -modified albumin (IMA), oxidized low-density lipoprotein (ox-LDL), @entity66 ( @entity66 ), and total antioxidant status in @entity1 with stable @entity1030 , compared with a control group. METHODS: This study was performed on 51 @entity1 with stable @entity1030 (42 @entity1 and 9 @entity1 ; mean age 56.92      3.0 years) and 45 healthy control @entity1 (32 @entity1 and 13 @entity1 ; 54.8      3.8 years). The levels of serum lipids, IMA, total antioxidant status, @entity66 , and ox-LDL were measured in all @entity1 . RESULTS: The levels of serum IMA, ox-LDL, and @entity66 were significantly higher in @entity1 with @entity1030 than those in control individuals. There was no difference between the levels of serum total antioxidant status, @entity1674 , total @entity165 , and low-density lipoprotein @entity165 (LDL-C) of @entity1 with @entity1030 and those of control individuals. Serum high-density lipoprotein @entity165 levels were significantly lower in @entity1 with @entity1030 than in control individuals. CONCLUSION: Our study indicated that serum IMA, ox-LDL, and @entity66 may be increased as a result of chronic @entity519 , @entity32 , and oxidative stress in @entity1 with severe and very severe stable @entity1030 . Our findings also revealed that IMA is higher in @entity1 with Global Initiative for @entity1030 Stages II, III, and IV, while @entity66 and ox-LDL are higher in @entity1 with Global Initiative for @entity1030 Stage IV. Measurements of serum IMA, @entity66 , and ox-LDL levels may be useful markers in the evaluation of stable @entity1030 .
