[Inducible @entity842 synthase and XXXX expression as prognostic factors in @entity957 ].

@entity1 @entity957 @entity540 @entity842 @entity3 @entity3623
BACKGROUND _ OBJECTIVE: The prognosis of @entity957 ( @entity957 ) was poor. To authors' knowledge, the relationship between inducible @entity842 synthase ( @entity3623 ) and @entity540 ( @entity540 ) and the prognosis of @entity957 has not been addressed to date. This study was designed to evaluate the prognostic significance of these two parameters in @entity957 . METHODS: The expression of @entity3623 and @entity540 protein in 64 @entity1 with @entity957 using LSAB method and pathologic imagine analysis system and their association with neck lymph node @entity3 , recurrence, and prognosis. RESULTS: (1) The expression of @entity3623 and @entity540 was significantly higher in cervical lymph node positive group (33.2+/-8.8 and 36.1+/-7.8) than in negative group (27.3+/-7.4 and 24.5+/-7.5) with statistical significance. The expression of @entity3623 and @entity540 was higher in recurrence group (36.9+/-1.7 and 34.6+/-2.0) than in no-recurrence group (29.1+/-1.3 and 27.2+/-1.4) with statistical significance. (2) @entity1 with positive neck lymph node had poorer 5-year survival than those with negative neck lymph node (31.0% vs. 57.1%). @entity1 with positive @entity3623 expression had poorer 5-year survival than those with the negative @entity3623 expression (40.0% vs. 77.8%). However, there was no statistical significance between positive @entity540 expression group and negative @entity540 expression group. (3) Cox model multivariate regression analysis showed that lymph node status, the expression of @entity3623 and postoperative radiotherapy were independent prognosis factors, whereas the T staging and the expression of @entity540 were not. CONCLUSION: The expression of @entity3623 was one of the independent prognostic factors, but it is necessary to study further for @entity3623 and @entity540 to predict the prognosis of @entity1 with @entity957 using immunohistochemical technique.
