Radical nephrectomy is still preferable in the treatment of XXXX . A long-term follow-up study.

@entity1 @entity5 @entity1358 @entity1011 @entity703
OBJECTIVES: Due to the advances of radiological methods, an increased number of incidentally detected @entity1358 is diagnosed. The reported excellent results of nephron-sparing surgery have promoted its application in @entity1 with a normal contralateral kidney. However, the risk of @entity5 recurrence and surgical complications after nephron-sparing surgery might be higher compared with radical nephrectomy. METHODS: In 89 @entity1 with @entity1358 treated with radical nephrectomy, long-term renal function, morbidity, and survival were evaluated. The renal function was followed up regularly with serum @entity1011 measurements. RESULTS: The cause-specific 5-year survival rate was 91.6%. There was neither local nor contralateral @entity703 recurrence in any @entity1 . Surgical complications were observed in 3% of the patients. Mean serum @entity1011 after the nephrectomy was 123 mumol/l without further increase during 10 years of follow-up. CONCLUSIONS: Radical nephrectomy of @entity1358 has low morbidity, excellent @entity5 control, and a high survival rate. For @entity1 with a normally functioning contralateral kidney the long-term renal function remained adequate. Based on these data, there is no convincing evidence justifying nephron-sparing surgery to be used routinely for @entity1 with a normally functioning contralateral kidney.
