Long-term outcome after resection of XXXX : report of 86 consecutive cases.

@entity1 @entity424 @entity41 @entity5 @entity204
BACKGROUND:                 <AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate progression-free survival, overall survival (OS) and long-term clinical outcome in a consecutive series of 86 @entity1 with @entity424 . METHODS: Medical charts were retrospectively reviewed. Surviving @entity1 voluntarily participated in a clinical history and physical examination that focused on neurological function and current @entity5 status. RESULTS: Follow-up data are nearly 100% complete; mean follow-up time was 82 months. Eighty-five @entity1 (99%) had surgery as a first-line treatment; 14 (17%) of these @entity1 received adjuvant radiotherapy. Of the 85 @entity1 who underwent primary surgery, gross total resection was performed in 60 @entity1 (71%) and subtotal resection in 25 @entity1 (29%). Ten-year progression-free survival rate was 75%; 5-year OS, 97%; and 10-year OS, 91%. Reduced preoperative neurological function and older age at diagnosis were significantly associated with increased risk of @entity204 . At follow-up, spontaneous regression of @entity41 after primary surgery may have occurred in 7 of 19 @entity1 (37%). More than 75% of @entity1 had neurological function compatible with an independent life at follow-up. Good preoperative neurological function was significantly associated with favorable outcome. It was not possible to evaluate the effect of radiotherapy on progression-free survival and OS. CONCLUSION: Gross total resection remains the optimal treatment for @entity1 with @entity424 . @entity1 should be monitored with a clinical examination and magnetic resonance imaging at regular intervals up to 10 years after surgery.
