Adjuvant radiotherapy in stage 1 XXXX : Evaluation of prognostic factors and results of survival.

@entity1 @entity235 @entity3 @entity4797 @entity65 @entity1349
PURPOSE: The purpose of this study was to evaluate the prognostic factors affecting @entity1349 ( @entity1349 ), cause-specific survival (CSS), progression-free survival (PFS), and survival among @entity1 undergoing adjuvant radiotherapy (RT) for stage-1 @entity4797 . MATERIALS AND METHODS: Between August 1997 and May 2013, 68 @entity1 diagnosed with stage-1 @entity4797 were retrospectively evaluated. The median age was 39 (24-74) years. All @entity1 received adjuvant RT after inguinal orchiectomy. Fifty-eight (85.3%) @entity1 received paraaortic RT; 10 (14.7%) received @entity235 -leg field RT. The median RT dose was 23.4 (23.4-30.6) Gy. RESULTS: The median follow-up period was 77.5 (6.7-198.5) months. During the follow-up period, two @entity1 developed distant @entity3 , and none developed local recurrence. Two @entity1 died from @entity4797 , and three died for other reasons. The 5, 10, and 15-year @entity1349 rates were 94.7%, 89.6%, and 89.6%, respectively. The 5, 10, and 15-year CSS rates were 98.5%, 96%, and 96%, respectively. The 5, 10, and 15-year PFS rate was 96.1%. The univariate analysis showed that only histological subtype was significant for @entity1349 . The 10-year survival rate was 100% among @entity1 with @entity4797 histology, 90.8% among @entity1 with a classic @entity4797 histology, and 50% among @entity1 with an @entity4797 histology (P < 0.001). A multivariate analysis showed that the @entity4797 was a negative prognostic indicator for @entity1349 (P = 0.042). CONCLUSION: Adjuvant RT resulted in excellent long-term survival and local control in @entity1 with stage-1 @entity4797 after orchiectomy. During a short follow-up, secondary malignancy (SM) and late @entity65 were not observed. Despite those results, concern of SM and late @entity65 remains.
