Histopathological study of specimens obtained by left ventricular biopsy during ventriculoplasty for XXXX .

@entity1 @entity82 @entity1289 @entity296 @entity6 @entity1184 @entity384 @entity3876 @entity1000
OBJECTIVE: Pathological changes in the myocardium in @entity1000 ( @entity384 ) are usually studied using endomyocardial biopsy specimens, but the relationship between pathological changes in the myocardium and clinical findings is unclear. The goal of the study was to examine correlations between clinical findings and histopathological findings in specimens of the left ventricular myocardium collected during left ventriculoplasty in @entity384 @entity1 . METHODS: The subjects were 20 @entity384 @entity1 (17 males and 3 females; mean age: 59    14 years old) who underwent left ventriculoplasty, including 16 cases of overlapping ventriculoplasty (OLVP) and 4 of papillary muscle approximation (PMA) with left ventricular incision. Preoperative age, sex, The New York Heart Association (NYHA) classification, the @entity3876 ( @entity3876 ) level, cardiothoracic ratio (CTR), echocardiographic data, history of @entity6 , drug history of spironolactone, @entity1289 inhibitor, ARB, and b-blocker were used as clinical findings. Histopathological scores were determined for each @entity1 and semi-quantitative data for @entity1184 , attenuation, vacuolation and @entity82 were obtained. RESULTS: A significant correlation was found between age and interstitial @entity82 . A significant inverse correlation was found between left ventricular diastolic diameter (LVDd) in echocardiographic data and interstitial @entity82 . There were no other significant relation between histopathological scores and clinical findings. CONCLUSION: From this study, we found that interstitial fibrous increased with aging and more dilated LVDd had less interstitial @entity82 . It is concluded that the kinetics of @entity296 with remodeling might be variable and histopathological findings does not reflect the clinical and hemodynamic changes in @entity384 @entity1 . Further morphological data are needed to verify this result.
