XXXX , @entity413 and @entity880 concentrations in umbilical cord blood in relation to umbilical artery flow patterns.

@entity1522 @entity4095 @entity2228 @entity519 @entity880 @entity4857 @entity413
OBJECTIVE: To study possible relationships between abnormal placental perfusion, @entity519 and impaired fetal nutrient supply. STUDY DESIGN: Umbilical artery flow velocity waveforms were assessed in high risk pregnancies and compared with controls. Three groups were studied. In group I (n = 13) the pulsatility index (PI) was within normal limits, in group II (n = 9) PI was > 2 S.D. in the presence of positive end diastolic velocities and in group III (n = 13) end diastolic velocities were absent. pH and @entity4095 levels and concentrations of @entity1522 , @entity413 and @entity880 were measured in umbilical blood obtained at cesarean section (n = 35). RESULTS: An inverse correlation was found between concentrations of essential @entity1522 concentrations and the pulsatility index in the umbilical artery (P = 0.03). No correlation with @entity519 was found (P = 0.32). The @entity2228 / @entity4857 ratio was significantly increased in the groups with abnormal Doppler velocity indices (P = 0.02). @entity413 concentrations were significantly reduced in the case of absent end diastolic velocities (P = 0.001). No significant differences were found between the three groups concerning @entity880 concentrations and acid-base balance parameters. CONCLUSIONS: These findings, especially the increased @entity2228 / @entity4857 ratio, which is characteristic for kwashiorkor, indicate that abnormal placental perfusion is associated with impaired fetal nutrient supply, in the presence of a normal fetal oxygenation.
