XXXX stimulates testosterone production while preventing oligospermia: a  randomized phase II clinical trial comparing topical testosterone.

@entity1 @entity4082 @entity258 @entity6126
OBJECTIVE: To determine the effect of @entity4082 in @entity1 with secondary @entity6126 . DESIGN: Phase II clinical trial. SETTING: Community dwelling @entity1 making visits to physician offices. @entity1 (S): @entity1 with secondary @entity6126 . INTERVENTION(S): Oral administration of @entity4082 or 1% topical T gel. MAIN OUTCOME MEASURE(S): Luteinizing hormone, FSH, T, and semen analysis. RESULT(S): Treatment with @entity4082 resulted in increased morning serum T, E2, and LH levels similar to those obtained with a topical T gel in @entity1 with secondary @entity6126 . Follicle-stimulating hormone and LH were increased with @entity4082 , and sperm counts were conserved. CONCLUSION(S): @entity4082 reverses the two hallmarks of secondary @entity6126 , namely, @entity258 and low or inappropriately normal LH while preserving sperm production. CLINICAL TRIAL REGISTRATION NUMBER: NCT01270841 (ClinicalTrials.gov Identifier NCT01270841).
