Impact of complications on long-term survival after resection of XXXX .

@entity1 @entity1419 @entity5 @entity260
BACKGROUND: The impact of @entity260 on the long-term outcomes of @entity1 undergoing surgery for @entity5 is unclear. The objective of the current study was to define the incidence of complications among @entity1 undergoing surgery for @entity1419 ( @entity1419 ) and identify the association between morbidity and long-term outcomes. METHODS: A total of 583 @entity1 undergoing surgery with curative intent for @entity1419 between 1990 and 2013 at 1 of 12 participating institutions were identified. The association between the occurrence and severity of @entity260 on long-term survival was analyzed. RESULTS: The median age of the @entity1 was 59.9 years and the majority of @entity1 were male (52.3%). A total of 91 @entity1 (15.6%) and 153 @entity1 (26.2%) developed a major and @entity260 , respectively; 18 @entity1 (3.5%) died within 90 days of surgery. Median, 1-year, 3-year, and 5-year recurrence-free survival were 10.0 months, 43.3%, 16.7%, and 11.1%, respectively. @entity260 (hazard ratio [HR], 1.37, 95% confidence interval [95% CI], 1.08-1.73 [P   =   .01]) and severity of complications (major vs none: HR, 1.55; 95% CI, 1.14-2.11 [P   =   .01]; minor vs none: HR, 1.30; 95% CI, 0.99-1.70 [P   =   .06]) independently predicted shorter recurrence-free survival. Median, 1-year, 3-year, and 5-year overall survival was 27.8 months, 76.8%, 39.0%, and 23.4%, respectively. @entity260 (HR, 1.64; 95% CI, 1.30-2.08 [P<.001]) and severity of complications (major vs none: HR, 1.79; 95% CI, 1.31-2.44 [P<.001]; minor vs none: HR, 1.50; 95% CI, 1.15-1.95 [P<.01]) independently predicted shorter overall survival. CONCLUSIONS: @entity260 were found to be independent predictors of worse long-term outcomes. The prevention and management of @entity260 is crucial to increase both short-term and long-term survival. @entity5 2015.    2015 American @entity5 Society.
