Pituitary adenylatecyclase-activating polypeptide-immunoreactive nerve fibers in the XXXX @entity2582 and pharynx.

@entity19381 @entity35 @entity9358 @entity4655 @entity2582
The distribution of pituitary adenylatecyclase-activating polypeptide-immunoreactive ( @entity19381 -IR) nerve fibers was studied in the @entity35 @entity2582 and pharynx. @entity19381 -IR nerve fibers were located beneath the mucous epithelium, and occasionally penetrated the epithelium. These nerve fibers were abundant on the laryngeal side of the @entity2582 and in the dorsal and lateral border region between naso-oral and laryngeal parts of the pharynx. @entity19381 -IR nerve fibers were also detected in taste buds within the @entity2582 and pharynx. In addition, many @entity19381 -IR nerve fibers were found around acinar cells and blood vessels. The double immunofluorescence method demonstrated that distribution of @entity19381 -IR nerve fibers was similar to that in @entity4655 -IR nerve fibers in the epithelium and taste bud. However, distributions of @entity19381 -IR and @entity4655 -IR nerve fibers innervating @entity9358 and blood vessels were different. The retrograde tracing method also demonstrated that @entity19381 and @entity4655 were co-expressed by vagal and glossopharyngeal sensory neurons innervating the pharynx. These findings suggest that @entity19381 -IR nerve fibers in the epithelium and taste bud of the @entity2582 and pharynx which originate from the vagal and glossopharyngeal sensory ganglia include nociceptors and chemoreceptors. The origin of @entity19381 -IR nerve fibers which innervate @entity9358 and blood vessels may be the autonomic ganglion.
