Long-term functional results and quality of life after colon interposition for long-gap oesophageal XXXX .

@entity1 @entity147 @entity354 @entity1146 @entity9666
Out of a series of 146 @entity1 with @entity354 (6.2%) underwent colon interposition from 1963 to 1971. All eight surviving @entity1 were seen at follow-up after a mean of 22 years. Three @entity1 were free of specific symptoms according to the criteria of DeMeester, two had moderate and three severe @entity147 . The mean time for consuming a standardized test meal was 15 minutes, compared to 8 minutes in healthy controls. @entity1 required 1-9 minutes to transport liquid @entity9666 through the transplant, compared to < 10 seconds in control subjects. Histological evaluation revealed a normal architecture of the colonic and ileal epithelium in three @entity1 who underwent endoscopy. In none of these @entity1 were contractions in the colon graft related to the act of swallowing recorded on manometry. Unimpaired quality of life was indicated by the Spitzer index which scored a mean of nine out of ten points. However, on a 100point visual analogue scale @entity1 scored their global quality of life 66 and the mean Gastrointestinal Quality of Life Index was 92.2, compared to 107.6 in healthy control subjects (p < 0.05). This impairment was exclusively due to specific symptoms which scored 49.3 in @entity1 and 59 in healthy individuals (p < 0.05). Physical and social functions, emotions, and inconvenience of a medical treatment were similar to control subjects. We conclude that colon interposition for long-gap oesophageal @entity1146 achieves acceptable long-term functional results. However, specific symptoms lead to a considerable impairment in quality of life.
