Preliminary results of tomotherapy for treatment of inoperable recurrent XXXX at bronchial stump site after right pneumonectomy.

@entity1 @entity499 @entity3618 @entity1149 @entity343 @entity4617
AIM OF THE STUDY: This study aimed to prospectively investigate the clinical outcomes of curative radical @entity499 ( @entity499 ) applied to recurrent @entity1149 ( @entity1149 ) at the bronchial stump site after right pneumonectomy. After right pneumonectomy, the heart shifted right laterally. The chambers of the heart closed with a recurrent mass at the bronchial stump were the right atrium and left atrium due to right shifting of the heart. The unfavorable bronchial stump recurrent @entity4617 due to a right shift of the heart might serve as a reliable predictor of cardiac morbidity for aggressive radiotherapy. MATERIAL AND METHODS: The 23 @entity1 received @entity499 for the recurrent @entity1149 at the bronchial stump site after right pneumonectomy between 2008 and 2011. The median age of the @entity1 was 65 years (range 56-74). RESULTS: We prescribed 95% volume of the primary planning target volume ( @entity343 ) to a total dose of 69 Gy in 30 fractions, and 95% of the secondary @entity343 to a total dose of 54 Gy in 30 fractions with reduction of the 50% volume of the heart < 20 Gy. The median conformal index in the 23 plans was 1.21. The mean fraction of primary @entity343 receiving more than 95% of the prescribed dose was 97.8%. The mean V45, V50, V60 of the heart were 10.5%, 6.5%, 0.2%, respectively. The median follow-up after tomotherapy was 19.86 months. Median survival was 20 months. The 2-year OS was 39.1%. CONCLUSIONS: The relatively high dose tomotherapy alone for @entity1 with a recurrent bronchial stump mass which was proximal to the heart demonstrated favorable clinical results without severe @entity3618 .
