Comparison of Stretta procedure and toupet fundoplication for XXXX -related extra-esophageal symptoms.

@entity1 @entity260 @entity354 @entity1282
AIM: To compare the outcomes between the Stretta procedure and laparoscopic toupet fundoplication (LTF) in @entity1 with @entity354 ( @entity354 )-related extra-esophageal symptoms. METHODS: From January 2011 to February 2012, a total of 98 @entity1 diagnosed with @entity354 -related extra-esophageal symptoms who met the inclusion criteria were enrolled in this study. All @entity1 who either underwent the Stretta procedure or LTF treatment have now completed the 3-year follow-up. Primary outcome measures, including frequency and severity of extra-esophageal symptoms, proton pump inhibitor (PPI) use, satisfaction, and @entity260 , were assessed. The results of the Stretta procedure and LTF therapy were analyzed and compared. RESULTS: There were 47 @entity1 in the Stretta group and 51 @entity1 in the LTF group. Ninety @entity1 were available at the 3-year follow-up. The total of the frequency and severity scores for every symptom improved in both groups (P < 0.05). Improvement in symptom scores of cough, sputum, and wheezing did not achieve statistical significance between the two groups (P > 0.05). However, the score for globus hysterics was different between the Stretta group and the LTF group (4.9    2.24 vs 3.2    2.63, P < 0.05). After the Stretta procedure and LTF treatment, 29 and 33 @entity1 in each group achieved PPI therapy independence (61.7% vs 64.7%, P = 0.835). The @entity1 in the LTF group were more satisfied with their quality of life than those in the Stretta procedure group (P < 0.05). Most complications resolved without intervention within two weeks; however, two @entity1 in the LTF group still suffered from severe @entity1282 2 wk after the operation, and it improved after bougie dilation treatment in both @entity1 . CONCLUSION: The Stretta procedure and LTF were both safe and effective for the control of @entity354 -related extra-esophageal symptoms and the reduction of PPI use.
