An FDA phase I clinical trial of XXXX sterilization (QS).

@entity1 @entity3543
OBJECTIVE: To review the significance of a United States Food and Drug Administration (FDA) approved Phase I clinical trial of a new use for an old drug, @entity3543 . To discover whether ultrasound may have utility in @entity3543 sterilization (QS). METHOD: This clinical trial began on 16 September 2000 at the @entity1 's and @entity1 's Hospital of Buffalo (WCHOB) in Buffalo, New York. Ten @entity1 volunteered to have QS. These subjects were carefully followed with regularly scheduled examinations, including extensive laboratory blood tests. In addition, each @entity1 had a trans-abdominal ultrasound examination six weeks or later past the date of the second insertion of @entity3543 . The trial was completed on 30 April 2003. RESULTS: Laboratory results fell within normal limits, thus providing additional evidence to affirm the lack of toxic effects of QS. With ultrasound, we were able to see scars in both oviducts on all of our @entity1 . One @entity1 with a small scar as seen on ultrasound became pregnant. CONCLUSION: QS was found to be safe and effective. Ultrasound holds the promise of reducing the failure rate.
