Transoral laser microsurgery outcomes with early XXXX : the Dalhousie University experience.

@entity5 @entity1 @entity135 @entity3
OBJECTIVE: To report the results of transoral laser microsurgery for the treatment of early @entity5 at our institution. DESIGN: Cohort study. Retrospective review of charts of @entity1 diagnosed with @entity5 stage 1 or 2 (early stage; no nodes or @entity3 ), previously untreated, primary @entity5 , treated with transoral laser microsurgery at the Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada. The minimum follow-up period was two years. SETTING: Tertiary care @entity135 centre. @entity1 : Fifty-three @entity1 treated between January 2002 and November 2007. OUTCOME MEASURE: Kaplan-Meier survival analysis for disease-free survival, overall survival and laryngectomy-free survival, at five years. RESULTS: The group comprised 46 @entity1 and seven @entity1 , with a mean age of 66 years (range 30-84 years). Mean follow up was 40 months (range 12-89 months). There were four cases of complications (7.5 per cent). Kaplan-Meier survival analysis revealed a five-year disease-free survival (including salvage) of 96.2 per cent, a five-year overall survival (all causes) of 88.8 per cent and a five-year laryngectomy-free survival of 98.1 per cent. CONCLUSION: Transoral laser microsurgery is a safe and effective initial treatment for early @entity5 , and has high rates of laryngeal preservation and disease-free survival.
