[ XXXX : age at disease onset].

@entity1 @entity161 @entity66
OBJECTIVE: Until now the problem of the typical age of @entity161 onset has been actively discussing in the world literature. Though there are more and more publications, which mention the growth in the number of cases with late-onset and @entity66 , a conviction that @entity161 is the illness of teenagers or young @entity1 is still exists. Author aimed to determine a preferable age of the onset of @entity161 . MATERIAL AND METHODS: Data obtained in multi-year epidemiological research in Mental Health Research Center (Moscow) were analized. The total number of @entity1 with @entity161 and spectrum disorders was 5486. A subgroup of the @entity1 with the diagnosis that met the current diagnostic criteria of @entity161 included 1108 @entity1 . The study was based on clinical-epidemiological and statistical methods. RESULTS: Most of @entity1 had early onset @entity161 (16-20 years old maximum). However, it mostly depended on demographic factors, because more than half of @entity1 were young or middle aged at the moment of the examination. The examination of the group aged over 60 years and those who conditionally belonged to this generation (if 100% would have lived to that age) showed that the maximum number of @entity1 had onset between 30-40 years old. CONCLUSION: This research demonstrates the essential predominance of cases with onset of the disease in adolescent and young age that may be rather related with demographic characteristics than pathogenetic mechanisms of @entity161 . The latter determine predominantly middle age of disease onset (30-40 years). Cases both with early and late onset of the disease are not rare and are random deviations from the mean valuation.
