Differentiation of @entity63 from nonischemic @entity296 during @entity452 stress by left ventricular long-axis function: additional effect of XXXX .

@entity1 @entity296 @entity452 @entity63 @entity714 @entity384 @entity11535 @entity453
BACKGROUND: Resting regional wall-motion abnormalities do not reliably distinguish @entity63 from nonischemic @entity296 . @entity452 stress echocardiography with use of the @entity11535 ( @entity11535 ) identifies @entity453 ( @entity453 ) in @entity384 ( @entity384 ), but the technique is subjective and further complicated by @entity714 ( @entity714 ). Long-axis motion is sensitive to @entity63 and can be assessed quantitatively. We aimed to compare long-axis function with @entity11535 for detecting @entity453 in @entity384 with or without @entity714 . METHODS AND RESULTS: Seventy-three @entity1 with @entity384 , 48 with @entity453 (16 with @entity714 ), and 25 without @entity453 (10 with @entity714 ) were studied. Long-axis M-mode, pulsed-wave tissue Doppler echograms (lateral, septal, and posterior walls), and @entity11535 were assessed at rest and at peak dobutamine stress. Failure to increase systolic amplitude (total amplitude minus postejection shortening) by 2 mm or early diastolic velocity by 1.1 cm/s was the best discriminator for @entity453 (systolic amplitude, sensitivity 85%, specificity 86%; lengthening velocity, 71% and 94%, respectively; P=NS). Both had greater predictive accuracy than did @entity11535 (sensitivity 67%, specificity 76%; P<0.001). The predictive accuracy of changes in septal long-axis function was similar to those of average long-axis function (systolic amplitude cutoff=1.5 mm, lengthening velocity cutoff=1.5 cm/s). However in @entity714 , systolic amplitude proved to be the only significant discriminator for @entity453 , with sensitivity and specificity reaching 94% and 100%, respectively (P<0.01 versus early diastolic lengthening velocity). CONCLUSIONS: Quantified stress long-axis function identifies @entity453 in @entity384 with greater sensitivity and specificity than does standard @entity11535 , particularly in the presence of @entity714 .
