Correlation of the apparent diffusion coefficient value and dynamic magnetic resonance imaging findings with prognostic factors in XXXX .

@entity1 @entity172 @entity1420 @entity5 @entity470 @entity513 @entity3 @entity1722
PURPOSE: To evaluate the correlation of the mean and minimal apparent diffusion coefficient values (ADC(mean) , ADC(minimal) ) and dynamic magnetic resonance imaging (MRI) findings with prognostic factors in @entity513 . MATERIALS AND METHODS: A total of 107 @entity1 with @entity3 underwent breast MRI. The ADC(mean) and ADC(minimal) of the @entity5 were computed. MRI findings were retrospectively evaluated according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon: mass or nonmass type, mass shape, mass margin, nonmass distribution, and enhancement pattern. Histological records were reviewed for @entity5 size, lymph node @entity3 , histologic grade, and expression of @entity172 receptors (ER), @entity1420 receptors (PR), @entity1722 ( @entity1722 ), Ki-67, and @entity470 ( @entity470 ). Correlations of ADC values and MR findings with prognostic factors were determined using the Mann-Whitney U-test and the Kruskal-Wallis test. RESULTS: The mean ADC(minimal) was 0.78    0.24 (  10      mm   /s), and the mean ADC(mean) was 1.01    0.23 (  10      mm   /s). There was a significant correlation of the ADC(mean) value with ER expression (P = 0.027) and @entity1722 expression (P = 0.018). There was no significant relationship between ADC(minimal) and prognostic factors or between ADC(mean) and traditional prognostic factors, PR, Ki-67 and @entity470 . The majority of the mass type lesions were less than 5 cm in size and the majority of nonmass type lesions were more than 2 cm in size (P = 0.022). The margin of mass was significantly associated with lymph node @entity3 (P = 0.031), ER expression (P = 0.013), PR expression (P = 0.036), @entity1722 expression (P = 0.019), and EGRF expression (P = 0.041). The rim internal enhancement was significantly correlated with Ki-67 expression (P = 0.008). CONCLUSION: The low ADC(mean) value was related to positive expression of ER and negative expression of @entity1722 . A spiculated margin was related to a good prognosis, but rim enhancement was associated with a poor prognosis.
