Metastatic XXXX in southern China during an 18-year period.

@entity1 @entity3169 @entity227 @entity0 @entity96 @entity5 @entity4 @entity2 @entity189 @entity735 @entity1358 @entity1829 @entity3 @entity158 @entity892 @entity1736 @entity259 @entity1319
OBJECTIVE: To determine the primary sites, clinical features, treatment, and outcome of 46 @entity1 with @entity5 metastatic to the orbits in southern China. METHODS: Retrospective review of medical records at a tertiary center in southern China between Jan 1, 1991 and Dec 31, 2008. RESULTS: The study included 35 males and 11 females, with an age range of 3-78  years (average 47  years). All of the @entity1 came from southern China. The left orbit was affected more frequently than the right orbit (3:2), and no cases were bilaterally involved. The most common primary @entity5 that metastasizes to the orbit is @entity189 (30.34%), followed by @entity2 (8.70%), @entity96 (6.52%), @entity0 (4.35%), @entity1358 (4.35%), @entity259 (2.17%), @entity189 (2.17%), @entity189 (2.17%), mediastinum @entity189 (2.17%), other forms (6.52%), and unknown @entity189 (30.34%). Orbital @entity3 was the first sign of systemic @entity5 in 24 @entity1 (52.17%). The five most common clinical findings at the initial examination were @entity735 (65.22%), proptosis (63.04%), increased orbital pressure (54.35%), @entity892 (54.35%), and @entity1319 (52.17%), followed by swollen eyelid (50%), visible mass or @entity4 (46%), @entity227 (41%), @entity3169 , and @entity4 (35%), @entity158 (28%), @entity1736 (20%), @entity1829 (17%), and vasodilatation of the retina (7%). Primary treatment included surgical excision, radiotherapy, systemic chemotherapy, and observation. Among the @entity1 (78% of 46) with sufficient follow-up time (mean 20.7  months), 30.56% of them died of disseminated @entity3 . Twenty-five percent of them were in remission with no active metastases and 27.78% of them were living with active metastases. Overall, the mean survival time was 18  months (range, 5-38  months) after diagnosis of orbital @entity3 . CONCLUSIONS: The most common primary @entity5 that metastasizes to the orbit is @entity189 (30.34%), followed by @entity2 (8.70%) and @entity96 (6.52%) in southern China. Orbital @entity3 can display a variety of clinical features and should be considered in @entity1 with known systemic @entity5 . The systemic prognosis is generally poor.
