Morphological and Functional Evaluation of @entity409 in Rosacea XXXX .

@entity1 @entity32 @entity2194 @entity409 @entity2526 @entity272 @entity6509
PURPOSE: Skin @entity6509 is a chronic @entity32 affecting up to 10% of the population in some European countries. Although considered a @entity272 , @entity6509 may involve the eyes, causing eyelid and ocular surface @entity32 . This study investigated the relationship between @entity272 and various signs of @entity2194 and evaluated severity of @entity409 in @entity6509 @entity1 . METHODS: The ocular surface and meibomian gland parameters were evaluated in 41 @entity1 with diagnosed @entity272 and 44 age-matched healthy controls. We analyzed meibomian gland function (meibum quality and meibum expressibility) and morphology (meibography) and lid margin alterations. We correlated our findings with self-reported ocular symptoms and @entity2526 (tear film breakup time, Schirmer test). RESULTS: The prevalence of ocular erythema and lid margin alterations was significantly higher in @entity6509 @entity1 compared with controls. We found that @entity6509 is accompanied with significant loss of meibomian gland tissue defined as reduced meibomian gland area and decreased meibomian gland density. A positive correlation between margin abnormality score and the extent of meibomian gland loss in @entity6509 group was observed (rs = +0.30, p = 0.005), suggesting that @entity6509 is accompanied by meibomian gland dropout. CONCLUSION: Skin @entity6509 is associated with ocular erythema and lid margin abnormalities. Our results suggest that ocular signs of @entity6509 may influence meibomian gland morphology, causing meibomian gland loss.
