Supersensitivity to @entity3044 and XXXX in right atria isolated from @entity35 submitted to a single swimming session.

@entity4235 @entity1425 @entity2819 @entity3044 @entity2072 @entity35 @entity2661 @entity1063
1. The effects of swim-induced stress on @entity35 atrial @entity1063 content, plasma @entity2819 level and pacemaker sensitivity to @entity2661 were studied. 2. Swimming for 50 min reduced the atrial @entity1063 content and induced a long-lasting increase in the plasma @entity2819 level. 3. Pacemakers isolated from swim stressed @entity35 showed supersensitivity to the chronotropic effect of @entity3044 . Sensitivity to @entity1063 was not significantly altered. Bilateral adrenalectomy or @entity4235 pretreatment prevented the development of swimming-induced supersensitivity to @entity3044 . After in vitro denervation and addition of @entity2072 supersensitivity to @entity1425 was demonstrated. 4. It is concluded that @entity2819 , at least partially, mediates the supersensitivity to @entity3044 and @entity1425 in pacemaker isolated from acutely swim stressed @entity35 .
