@entity409 : a distinctive XXXX of the liver with variable histologic appearances.

@entity1 @entity82 @entity2652 @entity75 @entity6437 @entity409 @entity194 @entity490 @entity1317 @entity1125
@entity409 can lead to the formation of a @entity6437 that can pose a diagnostic challenge. To better understand the full clinicopathologic spectrum of this @entity6437 , 18 cases were studied. Ages at presentation ranged from 14 to 91 years (median, 63 y) with a modest female- @entity1 predominance (13 of 18, 72%). Upper right quadrant @entity490 was the most common clinical presentation (14 of 18, 78%), and all the cases were mass lesions. The majority of cases were subcapsular (15 of 18, 83%) and ranged in size from 1.8 to 10.0 cm. All the cases contained abnormally thick-walled and often thrombosed vessels, with both arteries and veins affected. @entity1125 were a common finding (7 of 18, 39%). Examination of the entire series of cases suggested a sequence of changes, with @entity75 (n = 4) composed of collapsed hepatic parenchyma with preservation of portal areas, occasional islands of residual hepatocytes, and brisk bile ductular proliferation. These cases showed very mild @entity2652 . Other cases (n = 10) showed little or no ductular proliferation but had increased levels of @entity2652 . More advanced lesions (n = 3) were composed almost solely of @entity2652 with small scattered islands of unremarkable hepatocytes, whereas an end-stage lesion (n = 1) was a discrete nodule of @entity82 . In conclusion, segmental @entity194 of the liver is typically subcapsular, and is strongly associated with @entity1317 . The lesion has multiple stages ranging from parenchymal collapse, to @entity2652 , to nodular @entity82 . Recognizing the various morphologies will aid in proper diagnosis.
