The level of urinary a1 microglobulin excretion is a useful marker of peritubular capillaritis in antineutrophil cytoplasmic antibody associated XXXX .

@entity1 @entity4631 @entity8 @entity3335 @entity82 @entity1333 @entity194 @entity631 @entity19417
BACKGROUND: Antineutrophil cytoplasmic antibody (ANCA) associated @entity1333 affects small vessels in the kidney (i.e., arterioles, glomerular or peritubular capillaries, or venules). Although crescentic @entity631 is a common histological finding, the incidence of peritubular capillaritis (PTC) or @entity4631 is unclear. Moreover, the laboratory data that reflect the degree of @entity8 and distinguish between PTC and @entity4631 have not yet been clarified. METHODS: We investigated laboratory data and histological findings from 11 @entity1 diagnosed with @entity19417 (2 @entity1 and 9 @entity1 , mean age 70.3      3.3  years) whose renal biopsies were performed between 2009 and 2014. RESULTS: All @entity1 were positive for @entity3335 ( @entity3335 )-ANCA. PTC or @entity4631 was detected in six @entity1 (54.5  %), respectively. The only significant positive relationship between laboratory data and histological findings observed was that between levels of urinary a1 microglobulin (u-a1MG) excretion and the percentage of @entity194 and @entity82 (r  =  0.67, p  =  0.035). No significant differences in laboratory data were found between @entity1 with or without @entity4631 . However, the levels of u-a1MG excretion were significantly higher in @entity1 with PTC than in those without PTC (75.2      19.5 vs. 15.0      3.6  mg/dl, p  =  0.035). CONCLUSION: PTC or @entity4631 occurs at a high rate independently of crescentic @entity631 in @entity19417 @entity1 . The levels of u-a1MG excretion reflect the degrees of @entity194 and @entity82 . Moreover, high levels of u-a1MG excretion suggest that PTC is more likely than @entity4631 in @entity19417 @entity1 .
