Comparison of safety of left atrial catheter ablation procedures for @entity943 under continuous anticoagulation with XXXX versus @entity3924 .

@entity1 @entity64 @entity3924 @entity548 @entity956 @entity5424 @entity955 @entity1031 @entity943 @entity204
@entity5424 is increasingly used for @entity64 prevention in @entity1 with @entity955 . Data about the safety of left atrial radiofrequency ablation procedures under continuous @entity5424 therapy are lacking. We performed a matched-cohort study of @entity1 undergoing left atrium ablation procedures for @entity955 or left @entity956 . For each @entity1 on @entity5424 , 2 @entity1 on @entity3924 were matched by age, gender, and type of @entity943 . The primary safety end point was a composite of @entity548 , @entity1031 , and @entity204 . We identified 105 consecutive @entity1 (35 @entity1 ; mean age 63  years) on @entity5424 and matched 210 @entity3924 @entity1 (70 @entity1 , mean age 64  years). The primary end point was met in 11 @entity1 of the @entity5424 group and 26 @entity1 of the @entity3924 group (10.5% vs 12.3%, p  = 0.71). Major @entity548 complications occurred in 1 @entity1 of the @entity5424 group and 1 @entity1 of the @entity3924 group (1% vs 0.5%, p >0.99). @entity548 were observed in 10 @entity1 of the @entity5424 group and 25 @entity1 of the @entity3924 group (9.5% vs 11.9%, p  = 0.61). No @entity1 in either group experienced a @entity1031 event and no @entity1 died. In @entity1 on @entity5424 , no clinical variable was predictive for @entity548 complications. Left atrial ablation procedures under continuous oral anticoagulation with @entity5424 are feasible and as safe as under continuous oral anticoagulation with @entity3924 .
