Swallowing outcome measures in XXXX - How do they compare?

@entity1 @entity135 @entity601 @entity1282
OBJECTIVES: @entity1282 is a common and debilitating side effect of chemoradiotherapy. Assessment is difficult; swallowing is multifactorial and studies choose from a range of @entity1282 assessments. This study intended to investigate the relationship between swallowing assessments of @entity1282 in a cohort of @entity1 and to evaluate whether clinical swallowing measures can predict @entity1 reported swallowing outcomes. MATERIALS AND METHODS: One hundred and seventy-three @entity135 @entity1 from two teaching hospitals were recruited prospectively over 25months. At three months follow-up @entity1 were assessed using Rosenbeck's Penetration-Aspiration Scale (PAS), The 100ml Water Swallow Test (WST), The Performance Status Scale: Normalcy of Diet and the @entity601 Anderson @entity1282 Inventory (MDADI). RESULTS: The highest correlation was observed between the MDADI and Normalcy of Diet (rho 0.68) and the lowest between the MDADI and the PAS (rho 0.34). Using multiple regression the PAS and WST accounted for 44% of the variance in the MDADI scores (R(2)=0.44, F=37.8, p<0.001). On stepwise regression, the model only retained the Normalcy of Diet scores (R(2)=0.42, F=107.9, p<0.001). Separating the PAS into subgroups, those with no penetration or aspiration on the PAS scored significantly higher on the MDADI (p=<0.001). CONCLUSION: @entity1 reported swallowing outcomes were strongly aligned with diet restrictions but poorly aligned with clinical assessment. The WST, however, was more correlated than the PAS score, representing a more functional assessment. Clinical @entity1282 , associated with significant morbidity, and @entity1 reported @entity1282 related to quality of life are not interchangeable and must be measured separately.
