Assessment of quantitative corticospinal tract diffusion changes in @entity1 affected by XXXX using common available navigation software.

@entity1 @entity13 @entity5 @entity11 @entity51 @entity1893
OBJECTIVE: The aim of this study is to analyze the quantitative DTI parameters of the CST in @entity1 suffering from @entity11 affecting the CST using generally available navigation software. METHODS: A retrospective study was conducted on 22 subjects with diagnosis of primary @entity13 and preoperative @entity51 . Exclusion criteria were: involvement of motor cortex, lesion involving both hemispheres, previous surgical treatment. All @entity1 were studied using magnetic resonance imaging (MRI) with diffusion tensor imaging (DTI) sequences. Volume, fractional anisotropy (FA) and @entity1893 ( @entity1893 ) of the entire CSTs were estimated. Moreover, distance from midline, diameters, FA and @entity1893 were calculated on axial images at the point of minimal distance between @entity5 and CST. Statistical analysis was performed. RESULTS: There was a statistically significant difference of CST volume between affected and non-affected hemispheres (p<0.01). Mean overall/local FA, overall/local @entity1893 and sagittal diameter of CST were also significantly different between the two sides (p<0.05). Correlation tests resulted positive between the shift of CST and overall/local @entity1893 . Moreover there is significance between CST volume of @entity5 hemisphere and preoperative duration of @entity51 (p<0.05). CONCLUSION: The present study has demonstrated for the first time a significant difference of DTI based quantitative parameters of the CST between a @entity5 affected and a non-affected hemisphere in @entity1 with a corresponding motor deficit. This preliminary data suggests a correlation between DTI based integrity of CST and its function.
