Postchemotherapy resection of XXXX in @entity5 .

@entity1 @entity151 @entity5 @entity41
To determine the feasibility of post-chemotherapy resection of @entity41 in @entity151 , 24 selected @entity1 with limited-stage disease were evaluated for exploratory thoracotomy. All 24 @entity1 achieved partial or complete clinical response to chemotherapy and were considered adequate medical candidates for surgical resection. Fifteen @entity1 underwent a lobectomy or pneumonectomy, 13 of whom had @entity41 in the resected specimen. Of the nine remaining @entity1 , seven had no @entity5 found on biopsy at thoracotomy and two had unresectable mediastinal node involvement. No chemotherapy was administered postoperatively in any @entity1 until disease progression or relapse was documented. Median survival for the entire group was 19 months and did not differ according to the surgical procedure performed. Nineteen @entity1 had relapse. @entity1 undergoing biopsy only recurred locally in six of seven cases a median of five months post-thoracotomy (range one to six months). Two "biopsy only" @entity1 were @entity5 free at 34+ and 56+ months. Local recurrence was observed in six of 12 resected @entity1 , while six @entity1 experienced only extrathoracic metastases. Median time to recurrence for resected @entity1 was also five months. Four resected @entity1 experienced late recurrence 16 to 36 months postoperatively and were alive with @entity5 at 29+ to 42+ months. Two resected @entity1 were @entity5 -free at 13+ and 37+ months. Post-chemotherapy surgical resection was feasible in limited-stage @entity1 and improved local control of disease.
