Clinical-radiological presentation and outcome of surgically treated XXXX : a long-term single institution experience.

@entity1 @entity5 @entity2 @entity281 @entity358 @entity4303 @entity3
PURPOSE: To determine the presenting features and the outcome of surgically treated @entity5 . METHODS: Retrospective analysis of all consecutive cases with preoperatively suspected or proven @entity358 , treated between 1964 and 1994, in order to have full 5-year survival data. RESULTS: Seventy-three @entity1 were retrieved, six had a postoperative histology other than @entity4303 . The mean age of the 67 eligible cases was 44 years (range 17-74). There were 59 typical and eight atypical @entity4303 . The most frequent presenting symptom was @entity281 , followed by haemoptysis. Sixteen @entity1 were asymptomatic, 15 of these had an abnormal chest X-ray, showing a solitary nodule in 13. Bronchoscopy was abnormal in almost all symptomatic @entity1 . Bronchial biopsy results suggested a @entity5 in seven of eight @entity1 whose postoperative histology was found to be @entity4303 . There were 40 lobectomies, 14 bi-lobectomies, nine pneumonectomies, and four limited resections. Ten @entity1 had lymph node involvement (seven typical and three atypical). There was no correlation between the diameter of the primary @entity5 and the presence of nodal involvement. In particular, three of eight peripheral lesions <30 mm were found to have metastatic lymph nodes. The 5-year survival was 92% (95% in N0 versus 56% in N1-2; 92% in typical versus 67% in atypical). The 10-year survival was 84%. CONCLUSION: The specific diagnosis of @entity4303 cannot be reliably made on bronchial biopsies. No relationship was found between @entity5 size and the presence of lymph node @entity3 , suggesting that radical excision with detailed lymph node sampling is as important in @entity4303 as in other @entity2 . Long-term survival was excellent, nodal status and pathology (typical/atypical) were independent prognostic factors.
