[Musculoskeletal manifestations as the onset of XXXX in childhood].

@entity1 @entity4512 @entity981 @entity625 @entity5 @entity3052 @entity1503 @entity1431 @entity158 @entity491
OBJECTIVE: To study the frequency, the clinical features and laboratory exams of @entity1 with musculoskeletal symptoms at the onset of @entity3052 . METHODS: Retrospective, descriptive study including @entity1 diagnosed with @entity3052 , and treated at the Institute of Pediatric Oncology of UNIFESP, carried out from November 1999 to February 2000. The data on musculoskeletal complaints were obtained from a questionnaire. The medical records were revised in order to get data on the clinical examination and laboratory tests at the beginning of the illness. RESULTS: Sixty-one @entity1 were included in this trial, 93% with @entity981 , and 7% with @entity3052 . Thirty-eight @entity1 (62%) had @entity4512 at the onset. @entity625 was observed in eight @entity1 . The mean number of involved joints was 2.5 (1-6). The most frequently involved joints were the knees, ankles and elbows. Three @entity1 (4.9%) had normal blood count. Low hemoglobin was reported in 54 @entity1 (88%) (in six @entity1 it was the only @entity1503 ), @entity1431 in 14 (22%), @entity491 in 26 (42%) and low platelet count in 46 (75%). CONCLUSIONS: The musculoskeletal symptoms are common at the onset of @entity3052 so, @entity5 should always be ruled out in @entity1 presenting chronic or acute @entity625 or @entity158 . The laboratory tests may be normal at the onset of the illness, making differential diagnosis more difficult.
