Acute @entity715 of the Left Brachial Artery After Intra-Arterial Administration of XXXX .

@entity1 @entity2643 @entity1165 @entity1427 @entity432 @entity715 @entity857
OBJECTIVE: To report a case of intra-arterial @entity2643 injection in a hemodynamically unstable @entity1 leading to @entity432 and a subsequent compartment syndrome. DESIGN: Case report. SETTING: Prehospital setting, emergency department and ICU of a university hospital. @entity1 : A 58-year-old @entity1 presenting with a @entity1165 of 190 beats/min was administered @entity2643 through an accidently placed arterial access in the left cubital fossa. Quickly, the @entity1 developed clinical signs of an acute @entity432 . INTERVENTIONS: Immediate left brachial artery angiography with subsequent thrombectomy was performed. MEASUREMENTS AND MAIN RESULTS: A @entity715 at the injection side was found, which was immediately recanalized by thrombus aspiration. In addition to anticoagulation and an @entity857 -antagonist an adjunct therapy with vasodilators and @entity1427 /IIIa inhibitors was given and repetitive duplex sonography confirmed arterial flow. However, despite restoration of blood flow the @entity1 developed a severe compartment syndrome of the arm and had to receive multistep surgical interventions. CONCLUSIONS: This is the first report of an acute @entity715 leading to a compartment syndrome upon accidental intra-arterial injection of @entity2643 in an emergency setting. In the hemodynamically unstable @entity1 healthcare providers should be aware of arterial miscanulation and its consequences. Upon intra-arterial injection, a direct antithrombotic and vasodilative therapy should be administered via the initially misplaced arterial access, which may include a @entity1427 /IIIa inhibitor.
