XXXX : a retrospective study of 40 cases from India.

@entity1 @entity66 @entity1201 @entity1202 @entity5406 @entity1203
BACKGROUND: Rare variants of @entity1201 pose a diagnostic challenge even to astute clinicians and @entity1201 is one such form of disease with unique clinical and histopathological features. There are very few large series on this entity, mainly reported from India. OBJECTIVES: To study the epidemiological and clinical characteristics of @entity1 with @entity1201 . METHODS: We undertook this retrospective study including @entity1 registered with the @entity1201 clinic of our tertiary care referral centre from January 1991 to December 2006. Data regarding demographic details, clinical features, treatment, complications and course following treatment were extracted from the records of the @entity1201 clinic. RESULTS: The incidence of @entity1201 among the registered @entity1 of our clinic was 1.8% (40 of 2150). There was a significant male preponderance with a male/female ratio of 5.7 : 1. The anatomical areas of involvement were thighs/buttocks (67.5%), arms (62.5%), back (52.5%), face (47.5%), forearms (47.5%) and legs (35%) in descending order of frequency. This variety of @entity1201 was found most commonly in @entity1 with a primary diagnosis of @entity1203 (40%). De novo histoid lesions, i.e. lesions of @entity1201 developing without evidence of lesions of other types of @entity1201 in the Ridley-Jopling classification, appeared in 12.5% of @entity1 only. Only three @entity1 had received antileprosy treatment before presentation. Episodes of @entity5406 ( @entity5406 ) had occurred in 40% of @entity1 , although only one @entity1 manifested @entity5406 after the diagnosis of @entity1201 . The disease responded satisfactorily to the respective World Health Organization multidrug therapy regimens in all except in one @entity1 who relapsed with @entity1202 . CONCLUSIONS: As the bacillary load is very high in these @entity1 , they can form a potential reservoir of the infection in the community especially in the postleprosy elimination era. Contrary to the earlier belief in the dapsone era, most of our @entity1 @entity66 without any history of inadequate or incomplete antileprosy therapy.
