The Telehealth Enhancement of Adherence to Medication (TEAM) in pediatric XXXX trial: Design and methodology.

@entity1 @entity29 @entity146
Medication nonadherence is a significant health care issue requiring regular behavioral treatment. Lack of sufficient health care resources and @entity1 /family time commitment for weekly treatment are primary barriers to receiving appropriate self-management support. We describe the methodology of the Telehealth Enhancement of Adherence to Medication (TEAM) trial for medication nonadherence in pediatric @entity29 ( @entity29 ). For this trial, @entity1 11-18 years of age will be recruited from seven pediatric hospitals and will complete an initial 4-week run in to assess adherence to a daily medication. Those who take less than 90% of their prescribed medication will be randomized. A total of 194 @entity1 with @entity29 will be randomized to either a @entity146 ( @entity146 ) arm or education only (EO) arm. All treatments will be delivered via telehealth video conferencing. The @entity1 will be assessed at baseline, post-treatment, 3, 6, and 12 months. We anticipate that @entity1 in the @entity146 arm will demonstrate a statistically significant improvement at post-treatment and 3-, 6-, and 12-month follow-up compared to @entity1 in the EO arm for both medication adherence and secondary outcomes (i.e., disease severity, @entity1 quality of life, and health care utilization). If efficacious, the TEAM intervention could be disseminated broadly and reduce health care access barriers so that the @entity1 could receive much needed self-management intervention.
