Continuity resection of the mandible after XXXX - feasibility of oral rehabilitation with rhBMP-2 associated to @entity291 xenograft followed by implant installation.

@entity1 @entity291 @entity5 @entity1567
UNASSIGNED: Recombinant @entity1 morphogenetic protein (rhBMP) is a graft alternative for extensive mandibular reconstruction after @entity5 resections. However, the feasibility of rhBMP-2 to receive osseointegrated implants and prosthetic rehabilitation has been rarely reported. This study reports on a case of an extensive solid @entity1567 along the mandibular body. The treatment consisted of resection followed by off-label use of rhBMP type 2 associated with @entity291 bone xenograft. Eleven months postoperatively, the @entity1 was prosthetically rehabilitated with dental implants, without evidence of resorption or complications. The literature on mandibular reconstructions using rhBMP and their feasibility for future osseointegrated implant placement was also reviewed. Based on the presented case, the association between rhBMP-2 and a @entity291 bone xenograft could be considered a feasible option for the reconstruction and rehabilitation of large mandibular defects after @entity5 resection. According to the literature, the use of rhBMP as a graft material is encouraging, with good clinical outcome. However, there are no long-term studies demonstrating success and survival rates of implants placed in these grafts. Future investigations will be required to ascertain the long-term survival of implants in areas grafted with rhBMP. Also, there is a lack of information regarding the prosthetic rehabilitation of these @entity1 .
