Is it possible to define early distal XXXX ?

@entity1 @entity1697 @entity5 @entity189 @entity201 @entity3
PURPOSE: The feasibility of defining early @entity201 has not been adequately evaluated. The surgical outcomes of @entity1 who had undergone pancreatoduodenectomy (PD) for pathological T1 (pT1) distal @entity201 (DCC) were evaluated to determine whether it is possible to define early DCC. METHODS: The clinicopathological data of 18 @entity1 with pT1 DCC who had undergone PD were reviewed retrospectively. Depth of fibromuscular (fm) layer invasion was divided into two categories: fm1 and fm2 (without @entity3 and with @entity3 ). Comparative analyses were performed according to the depth of invasion. RESULTS: Disease-specific survival rates of @entity1 with five @entity5 and 13 fm-invasive @entity5 were 80 and 61.9  % at 5  years and 80 and 41.2  % at 10  years, respectively. There was no significant difference in disease-specific survival rates between the two groups (P   =   0.244). Disease-specific survival rates of @entity1 with 7 fm1-invasive @entity5 and 6 fm2-invasive @entity5 were 85.7 and 40  % at 5  years and 85.7 and 0  % at 10  years. A significant difference in disease-specific survival rates was observed between @entity5 and fm2-invasive @entity5 (P   =   0.043), and disease-specific survival rates of @entity5 and fm1-invasive @entity5 were similar (P   =   0.968). CONCLUSIONS: Defining early DCC as @entity189 confined to the fm of the bile duct might be inappropriate; early DCC should be limited to the @entity1697 .
