[New aspects in the diagnosis of XXXX in females].

@entity1 @entity296 @entity308 @entity1242 @entity3454 @entity741 @entity850
To investigate still uncertain aspects of the diagnosis of @entity741 ( @entity741 ) in @entity1 , between 1969 and 1984, repeated exercise studies were performed in 706 asymptomatic @entity1 (between the ages of 17 and 63 years). On observation of pathologic ST-segment @entity308 of more than 0.1 mV, the exercise study was repeated after administration of 0.8 mg @entity1242 . @entity308 was seen in 310 @entity1 (44%). In 217 @entity1 (31%), @entity1242 had no effect (NTG negative); in 93 @entity1 (13%), there was normalization of the ST-segment changes (NTG positive). Additionally, in selected subgroups of @entity1 , pulmonary artery pressure was measured at rest and during exercise and ECG mapping performed (n = 114); radionuclide ventriculograms (n = 64) and 201-thallium scintigrams (n = 99) were obtained and coronary angiography (n = 85) was performed. In the NTG-negative @entity1 , ejection fraction, myocardial perfusion and coronary arteries were normal. NTG-positive @entity1 had lower mean ejection fractions but still within normal limits and indications of @entity296 . High-grade coronary stenoses were found in 25%. No @entity1 with pathologic ST-segment @entity308 had @entity3454 . NTG-positive @entity1 had significantly more risk factors than NTG-negative @entity1 . In the former group, pulmonary artery pressure measurements showed pathologic exercise hemodynamics, only in 25% of whom @entity741 with significant @entity850 was found to be the cause. For this condition, differential diagnostic considerations include @entity296 .
