Diagnosis of XXXX has declined markedly with the advent of more sensitive troponin assays.

@entity1 @entity1187 @entity1459 @entity951 @entity583
BACKGROUND: Since the arrival of the universal definition of @entity583 more sensitive troponin assays have been developed. How these occurrences have influenced the proportions and clinical features of the components of @entity1187 have not been studied prospectively in unselected hospital @entity1 . METHODS: During 2010 we evaluated all @entity1 in whom cardiac troponin I had been measured at a single university hospital. The diagnosis of @entity583 ( @entity583 [ @entity583 ] or @entity583 [ @entity583 ]) was established in cases of a rise and/or fall of cardiac troponin I together with cardiac ischemic features. @entity1 with unstable chest discomfort and cardiac troponin I values below the decision limit of @entity583 were diagnosed as having @entity1459 . The definition of @entity1187 included @entity1459 , @entity583 , and @entity583 . Mortality data were obtained from the Danish Civil Personal Registration System. RESULTS: Of 3762 consecutive @entity1 , 516 had @entity1187 . Unstable @entity951 was present in 7%, @entity583 in 67%, and @entity583 in 26%. The @entity583 @entity1 were older, more frequently @entity1 , and had more comorbidities than @entity1 with @entity1459 and @entity583 . At median follow-up of 3.2 years 195 @entity1 had died: 14% of @entity1459 , 45% of @entity583 , and 25% of @entity583 @entity1 . Age-adjusted log-rank statistics revealed differences in mortality: @entity583 vs @entity1459 (P  = .0091) and @entity583 vs @entity583 (P  = .0045). CONCLUSIONS: The application of the universal definition together with the use of a contemporary troponin assay seems to have reduced the proportion of @entity1 with @entity1459 to the benefit of @entity1 with @entity583 . Despite this, @entity583 @entity1 have a sustained higher mortality than @entity1 with @entity583 .
