Partial axillary lymph node dissection inferior to the @entity129 complements sentinel node biopsy in XXXX with clinically node-negative @entity0 .

@entity129 @entity1 @entity0 @entity4269 @entity1600 @entity6693 @entity1817
BACKGROUND: The practice of @entity0 and treatment in China varies to that in western developed countries. With the unavailability of radioactive tracer technique for @entity1600 ( @entity1600 ), using blue dye alone has been the only option in China. Also, the diagnosis of @entity0 in most Chinese centres heavily relies on intraoperative instant frozen histology which is normally followed by sentinel lymph nodes mapping, @entity1600 and the potential breast and axillary operations in one consecutive session. This practice appears to cause a high false negative rate (FNR) for @entity1600 . The present study aimed to investigate the impact of the current practice in China on the accuracy of @entity1600 , and whether partial axillary lymph node dissection (PALND), dissection of lymph nodes @entity129 (ICBN), was a good complementary procedure following @entity1600 using blue dye. METHODS: 289 @entity1 with clinically node-negative @entity0 were identified and recruited. Tumorectomy, intraoperative instant frozen histological diagnosis, @entity1600 using @entity6693 dye, and PALND or complete @entity1817 ( @entity1817 ) were performed in one consecutive operative session. The choice of @entity1600 only, @entity1600 followed by PALND or by @entity1817 was based on the pre-determined protocol and preoperative choice by the @entity1 . Clinical parameters were analyzed and survival analysis was performed. RESULTS: 37  % @entity1 with clinically negative nodes were found nodes positive. 59 @entity1 with positive SLN underwent @entity1817 , including 47 @entity1 with up to two positive nodes which were all located inferior to the ICBN. 9 @entity1 had failed @entity1600 and underwent PALND. Among them, 3 (33.3  %) @entity1 were found to have one metastatic node. 149 @entity1 showed negative @entity1600 but chose PALND. Among them, 30 (20.1  %), 14 (9.4) and 1 (0.7  %) @entity1 were found to have one, two and three metastatic node(s), respectively. PALND detected 48 (30.4  %) @entity1 who had either failed @entity1600 or negative @entity1600 to have additional positive nodes. All the @entity1 with up to two positive nodes had their nodes located inferior to the ICBN. The FNR of @entity1600 was 43  %. The accuracy rate was 58  %. The follow-up ranged 12-33 months. The incidence of @entity4269 for @entity1600 , PALND, and @entity1817 was 0  %, 0  %, and 25.4  %, respectively (P   <   0.005). The disease-free survivals for @entity1600 , PALND, and @entity1817 groups were 95.8  %, 96.8  %, and 94.9  %, respectively (p   >   0.05). CONCLUSIONS: Under the circumstances of current practice in China, PALND is a good complementary procedure following @entity1600 in clinically node-negative @entity0 .
