Hypofractionated radiation therapy in the treatment of superior XXXX .

@entity1 @entity4264 @entity848 @entity2
We retrospectively reviewed 46 @entity1 with superior @entity4264 during the period 1986-1992. The common symptoms included congestion of collateral veins of the neck, anterior chest wall, face, eyelids and right arm. Dyspoea and @entity848 occurred less frequently. In all but two @entity1 a histological diagnosis was made by invasive and non-invasive examination without complications. In 82% of all @entity1 a primary @entity2 was the cause of the superior @entity4264 . For 39 @entity1 radiotherapy was the first treatment of choice. To relieve the distressing symptoms @entity1 received one of two regimens employing hypofractionated radiotherapy. In regimen 3F, 25 @entity1 received three weekly high dose fractions of 8 Gy delivering a total dose of 24 Gy. Regimen 2F, applied to seven @entity1 , consisted of two weekly fractions of 8 Gy, giving a total of 24 Gy. In both regimens a good palliative result was established, however the results of the 3F regimen were superior. Using the 3F regimen a partial response was obtained in 96% of all @entity1 , and 56% achieved a complete response. With the 2F regimen a partial response was achieved in 70% of all @entity1 , and a complete response in only 28%. Minimal side effects were noted. After reviewing our experience, the 3F regimen is recommended for rapid and effective relief of the superior @entity4264 .
