Poor prognosis despite aggressive treatment in adults with intramedullary spinal cord XXXX .

@entity1 @entity75 @entity5 @entity1514 @entity4097 @entity463 @entity2359
UNASSIGNED: We report our institution's experience with adult @entity1 who underwent surgery for intramedullary spinal cord @entity463 . Spine involvement of @entity463 is rare, representing 7.5% of all intramedullary gliomas and 1-3% of all @entity4097 . We performed a retrospective review of five male @entity1 with intramedullary spinal cord @entity463 who underwent surgical resection from 1990 to 2014. Demographic, operative, and postoperative factors were recorded. The median age at treatment was 31years (range: 18-61) and all @entity1 presented with @entity2359 . Two had prior surgical resection of an intramedullary World Health Organization Grade III anaplastic @entity75 with adjuvant chemoradiation. All @entity5 were present in the cervical (n=2; 40%) or @entity1514 (n=3; 60%) spine, spanning a median of three levels (range: 2-4). Gross total resection was achieved in three @entity1 (60%), and there were no intraoperative mortalities or complications. Although one had improvement in his neurological status postoperatively, all five @entity1 died with a median time to death of 20months (range: 2-31). Adult intramedullary spinal cord @entity463 is rare, and despite aggressive treatment, prognosis is poor, with a median survival in our series of only 20months. New treatment strategies are necessary to improve survival in this @entity1 population.
