[Effect of combined use of adrenocortical hormones and XXXX as anti-emetics during @entity900 therapy].

@entity1 @entity1667 @entity390 @entity900 @entity391 @entity448 @entity2211 @entity617
Eighteen @entity1 received repeated administrations of @entity900 in relatively large amounts (55-75-100 mg/m2) given systemically by drop infusion. As antiemetic treatments, the following were scheduled: on the day before; @entity617 30mg (3 X p.o.), immediately before; @entity1667 500mg (i.v.), and 3 hours after administration of @entity900 ; @entity1667 500mg (i.v.) and @entity2211 60 mg (suppo.). @entity2211 was given twice a day for one week. @entity390 , @entity391 and @entity448 were studied objectively for two weeks. At a dose of 75 mg/m2 of @entity900 , the occurrence and the duration of @entity390 and @entity391 were effectively reduced by the regimen; @entity390 was observed in 67% of all cases (average duration: 3.3 days) and @entity391 was experienced in 40% (1.2 days). @entity448 was observed in 67% of cases and lasted longer (5.2 days). The severity and duration of these side effects of @entity390 , @entity391 and @entity448 seemed to appear in a manner related to the dose of @entity900 given, but even at a dose of 100 mg/m2, the regimen described above reduced the @entity1 ' discomfort to acceptable levels. No remarkable side effect of this anti-emetic regimen was evident.
