[Dynamic and long-lasting expression of @entity7102 receptor-1 after @entity1779 in XXXX ].

@entity2657 @entity8225 @entity7102 @entity35 @entity1779
AIM: To study the dynamic and long-lasting expression of @entity7102 receptor after acute @entity1779 ( @entity1779 ) in @entity35 . METHODS: 36 @entity35 were randomly divided into 6 groups (n = 6): Normal group and @entity1779 model groups at 6 hours, 24 hours, 3 days, 7 days and 14 days. @entity1779 models were produced with the induction of collagenase type VII-S. Immunohistochemical method was used to detect @entity8225 protein and RT-PCR technique was used to detect @entity8225 mRNA in brain tissue around the haematoma in different groups. RESULTS: @entity8225 protein and mRNA were mild positive in normal group. In model groups, intensity of @entity8225 expression started to enhance at 6 hours, and enhanced more at 24 hours. @entity8225 expression reached the peak at 3 days and began to descend. At 7 days the descent was obvious and there was further descent at 14 days. At each time point, the @entity8225 protein positive cell number and @entity8225 mRNA absorbance ratio in @entity1779 model groups were significantly higher than those in normal group (P < 0.05 or P < 0.01). In addition, @entity8225 proteins were obviously expressed in vivo in brain capillary endothelial cell. CONCLUSION: Functional @entity8225 exists in brain capillary endothelial cells. Activation of @entity8225 after @entity1779 due to the stimulation of @entity7102 is not only the initiating agent of @entity2657 after @entity1779 , but also participates the development of @entity2657 .
