Males with XXXX and nonneurogenic @entity1494 .

@entity1 @entity1494 @entity384 @entity508 @entity3041 @entity1467 @entity751 @entity1011 @entity29082 @entity293
PURPOSE: We assessed the relationship of trisomy 21 with the most severe dysfunctional elimination syndrome, nonneurogenic @entity1494 or the @entity751 . MATERIALS AND METHODS: We retrospectively reviewed our experience with @entity1 with @entity1467 (trisomy 21) in a 10-year period and identified a subset who presented for the evaluation and treatment of @entity293 associated with severe @entity29082 . RESULTS: Four males 9 months, 14 years, 18 years and 21 years old met the criteria for review. All @entity1 underwent radiological and urodynamic evaluation, and were diagnosed with @entity3041 and prostatic @entity384 with pelvic floor @entity508 . Renal function studies showed a @entity1011 of 0.7 mg./dl. in the 9-month-old, 1.2 mg./dl. in the 14-year-old, 1.9 mg./dl. in the 18-year-old and 2.2 mg./dl. in the 21-year-old @entity1 . Three @entity1 underwent surgical treatment to protect the upper urinary tract, including @entity1494 and an appendiceal Mitrofanoff stoma in 2, and vesicostomy in 1. The remaining @entity1 was treated conservatively with a behavioral modification program that included timed voiding and a bowel regimen. CONCLUSIONS: @entity1 with trisomy 21 may be at risk for the @entity751 . Surgical intervention and clean intermittent catheterization for renal preservation and continence can be performed in this population despite intellectual impairment. Further evaluation is necessary to determine whether this relationship is more common than appreciated and whether this syndrome occurs in females with trisomy 21.
