Injection of intradiscal o2-o3 to reduce @entity158 and disability of @entity1 with XXXX due to prolapsed lumbar disk.

@entity1 @entity1643 @entity26 @entity158 @entity717 @entity1787 @entity890
BACKGROUND: @entity890 ( @entity890 ) is one of the most common disk lesions, inducing @entity1643 ( @entity1643 ). Various therapeutic options have been proposed for treatment of @entity890 ( @entity890 ). Intradiscal injection of @entity1787 has been suggested for treatment of @entity890 . OBJECTIVES: To determine the effect of intradiscal @entity1787 injection on @entity158 score and disability in @entity1 with @entity1643 from disk prolapsed. @entity1 AND METHODS: @entity1 with @entity1643 diagnosed with @entity890 were enrolled in this clinical trial study. After prep and drape the area and under the fluoroscopy guide (c-arm), intradiscal injection of @entity1787 / @entity26 mixture (4 mL, 40   g/mL) was performed. @entity158 score and functional ability of the @entity1 according to @entity717 Index (ODI) were measured prior to the injection (baseline) and then at 2 and 4 weeks and then at 3 and 6 months after the injection. RESULTS: Thirty @entity1 (17 females, 13 males) with the mean age of 58.6 y (range, 42-73 y) enrolled in the study. The mean    standard deviation (SD) of @entity158 score before intervention was 8.1    0.8. After two weeks, it was reduced to 3.2    0.6 (P < 0.001) and finally dropped to 2.0    0.6 sixth months after intervention (P = 0.0001). Functional status of ODI was 28.5    2.1 before intervention and showed significant reduction after two weeks (with the mean of 12.3), and it was almost sustained till sixth months after intervention, with the mean of 11.4 (P = 0.001). CONCLUSIONS: Altogether, @entity1787 had significant positive effects on @entity1 with @entity890 unresponsive to other conservative and minimally invasive treatments.
