Urinary tract infection and @entity8 in sibling XXXX .

@entity1 @entity8 @entity3025 @entity9409
PURPOSE: Siblings of index @entity1 with @entity3025 are known to have an increased incidence of reflux. Previously reported studies have evaluated @entity3025 in asymptomatic siblings of @entity1 who were previously proved to have reflux. We determine the incidence and nature of @entity3025 in symptomatic siblings of @entity1 with documented @entity3025 . MATERIALS AND METHODS: Between January 1990 and December 1996, 624 @entity1 were diagnosed with @entity3025 during the investigation of documented urinary tract infections. All @entity1 were evaluated for reflux by contrast voiding cystourethrography and reflux was graded according to the international reflux study. 99mTechnetium @entity9409 nuclear renal scans were performed to detect renal scarring. The medical records and voiding cystourethrograms of the 624 consecutive @entity1 with @entity3025 were retrospectively reviewed to identify siblings with @entity3025 . RESULTS: Vesicoureteral reflux was noted in 85 siblings (134 refluxing ureters) of the 624 index @entity1 (13.6%), including 1 and 2 siblings of 38 and 3 @entity1 , respectively. Mean age at presentation of the 37 @entity1 and 48 @entity1 was 2.5 years. Reflux was unilateral in 36 siblings and bilateral in 49. Reflux was grades I to V in 8, 9, 51, 55 and 11 ureters, respectively. Nuclear scan revealed @entity8 in 22 of the 77 tested siblings (28.5%). CONCLUSIONS: When @entity3025 is discovered in symptomatic siblings, it is usually high grade and associated with a higher incidence of @entity8 . Of further interest are the findings that refluxing symptomatic siblings of index @entity1 are usually younger and @entity1 are as commonly affected as @entity1 . Screening for @entity3025 in asymptomatic siblings is recommended to decrease the incidence of @entity8 .
