[Influence of XXXX polymorphism in @entity7160 ].

@entity1 @entity97 @entity82 @entity3531 @entity2204 @entity99 @entity7160
OBJECTIVE: To assess whether the polymorphism of apolipo-protein E was associated with the development of @entity7160 and could influence the severity of @entity99 evaluated by the @entity1 -Pugh score. METHOD: We investigated 75 alcoholic @entity1 with a histological diagnosis of @entity82 , with negative @entity97 , @entity3531 serology and a control group of 54 subjects. Polymorphism of @entity2204 was performed using PCR. RESULTS: There was no difference for the allele frequency and the genotype in the cirrhotic group and the control group. Cirrhotic @entity1 with allele epsilon 2 had higher concentration of albumin (P = 0.01) and a higher level of apolipoprotein AII (P < 0.05) than those with allele epsilon 3. They also had a higher concentration of apolipoprotein AI than cirrhotic @entity1 with allele epsilon 3 and epsilon 4 (P = 0.01). There was a statistical difference between the three genotype groups for prothrombin time (P = 0.01). There was no statistical difference between the three genotype groups for @entity1 -Pugh score. CONCLUSIONS: Polymorphism of @entity2204 was not associated with the development of @entity7160 . However @entity1 with allele epsilon 2 had better hepatocellular function.
