[Evaluation of XXXX @entity1370 using equilibrium radionuclide ventriculography. I. Results at rest].

@entity1 @entity632 @entity64 @entity20183 @entity1370
Results of 606 equilibrium radionuclide ventriculographies performed in 348 non-selected @entity1 receiving @entity632 (ADM) therapy were stored in a data base system. The aim of the study was to assess the influence of a potential @entity1370 therapy on left ventricular pump function. Increasing ADM doses yielded a significant (p less than 0.05) decrease of the resting ejection fraction (R- @entity20183 ), the peak ejection rate and the peak filling rate. End diastolic and end systolic volumes increased significantly. @entity64 volume, heart rate and time to peak filling rate did not change significantly. 368 follow-up studies were performed in 128 @entity1 : 65/128 @entity1 presented a decrease of R- @entity20183 , but only in 45 of these @entity1 R- @entity20183 values fell into the pathologic range. In 44 of these follow-ups, R- @entity20183 remained unchanged. In 19 @entity1 , a R- @entity20183 increase was observed. At the beginning of ADM therapy 14% of the @entity1 had subnormal R- @entity20183 values. With increasing ADM doses pathologic findings increased to 86% in @entity1 with ADM doses higher than 500 mg/m2.
