Impact of jejunostomy during esophagectomy for XXXX on health related quality of life.

@entity5 @entity1 @entity353 @entity260
BACKGROUND: The aim of this study was to evaluate the impact of jejunostomy during esophagectomy for @entity5 on postoperative health-related quality of life (HRQL). METHODS: We evaluate all consecutive @entity1 who underwent esophagectomy for @entity5 at the surgical oncology unit of the Veneto Institute of Oncology (IOV-IRCCS) between January 2008 and March 2014. The primary outcome was HRQL, which was assessed using nine scales of EORTC C30 and OES18 questionnaires. General linear models were estimated to evaluate mean score difference (MD) of each selected scale in @entity1 with and without jejunostomy, adjusting for clinically relevant confounders. The secondary outcomes were morbidity, hospital stay, postoperative @entity353 . RESULTS: Jejunostomy was performed in 40 on 109 @entity1 (41.3%) who participated in quality of life investigation. A clinically and statistically significantly worse eating at admission (P=0.009) became not clinically significant at 3 months after surgery (MD =9.1). Jejunostomy was associated to clinically and statistically significantly poorer emotional function (EF) at 3 months after surgery (MD =-15.6; P=0.04). Hospital stay was longer in jejunostomy group (median, 20 vs. 17 days, P=0.02). CONCLUSIONS: In our series @entity1 who had a jejunostomy during esophagectomy had been selected for their risk for @entity260 . However, their postoperative outcome was actually similar compared to those without jejunostomy. Nevertheless, jejunostomy was associated to clinically and statistically significantly poorer EF at 3 months after surgery. Therefore, @entity1 candidate to esophagectomy and feeding jejunostomy should receive additional psychological support.
