XXXX --a case for hemispherectomy?

@entity1 @entity410 @entity4289 @entity2916 @entity6788
Two @entity1 are described with intractable, drug-resistant @entity410 from birth associated with an enlarged cerebral hemisphere. The first died at sixteen months and demonstrated arrested head growth. Histology of the abnormal hemisphere showed disturbed cortical architecture, and @entity4289 with multinucleate cells resembling @entity2916 cells. Continuous fitting persisted in the second @entity1 following callosal section. Hemispherectomy was undertaken in an attempt to preserve function of the "normal" hemisphere. @entity410 ceased and head growth velocity accelerated. The neuropathology of the excised hemisphere is compared with the first case. From the literature this is the first report of a favourable outcome after hemispherectomy for @entity6788 . The finding of an echodense enlarged hemisphere may allow presumption of this diagnosis in a neonate with unilateral @entity410 . After CT scan the diagnosis may be confirmed histologically providing that a precisely orientated frontal biopsy is submitted to the neuropathologist. We suggest that very early hemispherectomy may be the treatment of choice for this condition.
