Undercarboxylated XXXX is associated with @entity2690 resistance, but not @entity1254 , during pregnancy.

@entity1 @entity6 @entity19 @entity2450 @entity2690 @entity1254 @entity164 @entity413
UNASSIGNED: In @entity19 , undercarboxylated @entity2450 (ucOC) improves beta-cell function and @entity2690 sensitivity through @entity1254 . In @entity1 , levels of total @entity2450 (OC) and ucOC were negatively correlated with @entity2690 resistance (IR) indices in @entity1 with @entity164 2 @entity6 . Whether ucOC plays a role in @entity413 homeostasis and whether its effect is mediated through @entity1254 during pregnancy is unclear. Serum levels of total OC, ucOC, and @entity1254 were measured in 130 pregnant @entity1 with varying degrees of IR [ @entity6 ( @entity6 ), n  =  74 and non- @entity6 , n  =  56]. In all @entity1 , total OC and ucOC levels were positively correlated with HOMA-IR and HOMA-%B, and negatively correlated with QUICKI. In contrast, @entity1254 levels were negatively correlated with HOMA-IR and positively correlated with QUICKI (P  <  0.01, both). However, neither total OC nor ucOC was associated with @entity1254 . Although none of these markers could help distinguish @entity1 with and without @entity6 , total OC and ucOC levels were significantly higher in non- @entity6 @entity1 who had 1 abnormal OGTT value than those who had all normal OGTT values. Total OC and ucOC levels were significantly correlated with @entity2690 secretion and IR indices, but not @entity1254 levels, in pregnant @entity1 . Changes in OC might be a sensitive response to increased IR during pregnancy, which was not mediated through @entity1254 .
