Platelet associated IgG, platelet survival, and platelet sequestration in XXXX states.

@entity1 @entity7027 @entity882 @entity4558 @entity3039
Platelet-associated IgG (PAIgG), platelet @entity7027 ( @entity7027 ), and platelet sequestration sites were studied in 69 @entity1 with immune ( @entity3039 ) and presumed nonimmune @entity882 (NTP). A shortened @entity7027 was associated with elevated PAIgG (N = 46), and with normal PAIgG (N = 15). Four @entity1 had a normal @entity7027 , but elevated PAIgG, four @entity1 were normal for both parameters. The highest PAIgG values occurred in @entity3039 @entity1 with a very short @entity7027 . Nine NTP @entity1 had also elevated PAIgG, but a normal or slightly shortened @entity7027 . There was a significant double log correlation between PAIgG and @entity7027 for @entity3039 , but not for NTP @entity1 . Judged from the coefficient of determination, only 10% of PAIgG were directly related to a shortened @entity7027 . 70% of @entity1 (N = 63) had exclusively @entity4558 and 30% hepatosplenic sequestration. PAIgG was elevated in 29/44 @entity1 with @entity4558 (66%) and in 16/19 @entity1 with hepatosplenic sequestration (84%). In @entity3039 , PAIgG-positive cases were observed in 69% of @entity4558 v 82% of hepatosplenic sequestration, while in NTP the corresponding figures were 6/11 and 2/2. No significant correlation between PAIgG and either sequestration type was demonstrable. We conclude that in immunologically mediated @entity882 only a small portion of PAIgG accounts for a decreased @entity7027 , and that the concentration of PAIgG per se does not determine the platelet sequestration type.
