A Clinicopathological Analysis of Recurrent XXXX .

@entity1 @entity5 @entity356
PURPOSE: This study was designed to investigate the correlation between the clinicopathologic characteristics and the recurrence pattern of @entity356 and to define survival difference according to treatment modality after diagnosis of recurrence. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 4184 @entity1 who had undergone radical surgery for primary @entity356 from 1986 through 1996. Clinicopathologic factors were analyzed for the relationship of each factor with the pattern of recurrence. And the survival after diagnosis of recurrence was compared among the treatment modalities. RESULTS: Recurrence pattern was confirmed in 1141 @entity1 . Loco-regional recurrence occurred in 291 @entity1 (20.1%), peritoneal recurrence in 383 (26.5%), distant recurrence in 290 (20.1%), and mixed recurrence in 177 (12.3%), respectively. Early recurrence (less than 2 years) occurred in 767 (69.3%), intermediate recurrence (2~5 years) in 286 (25.8%), and late recurrence (more than 5 years) in 54 (4.9%). In multivariate analysis, T stage, N stage, size of @entity5 and perineural invasion were independent prognostic factors for recurrence. Median survival from diagnosis of recurrence was 24.2 months in the curative operation group, 7.7 months in the chemotherapy group, 7.1 months in the non-curative operation group and 3.3 months in the conservative treatment group, respectively (p=0.000). CONCLUSION: The clinicopathological analysis of recurrent @entity356 showed recurrent patterns and prognostic factors. Curative resection is suggested to have survival benefit in recurrent @entity356 @entity1 , although it was possible in @entity1 with limited extent of disease.
