Ovarian XXXX as the cause of virilization in 45,X @entity2689 .

@entity43 @entity1 @entity1619 @entity16438 @entity1373 @entity2689 @entity2670
OBJECTIVE: To describe a rare case of 45,X @entity2689 with @entity1619 and clitoromegaly caused by @entity43 . DESIGN: Case report. SETTING: Tertiary care pediatric hospital. @entity1 (S): An 11-and-a-half-year-old @entity1 with 45,X karyotype showed signs of accelerated growth and clitoromegaly and was found to have elevated serum T. Fluorescence in situ hybridization was used to confirm her karyotype as monosomy X and absence of the @entity16438 gene. Elevated gonadotropins indicated @entity2670 . INTERVENTION(S): Laparoscopic bilateral gonadectomy. MAIN OUTCOME MEASURE(S): Serum T level. RESULT(S): Pathology showed @entity43 within the removed gonads. Serum T levels returned to normal after gonadectomy. CONCLUSION(S): Ovarian @entity1373 is an extremely rare cause of virilization in @entity2689 . Gonadectomy should be considered for @entity1 with confirmed 45,X karyotype who exhibit virilization.
