[Study on the correlation between prethrombotic biomarkers and traditional Uyghur medicinal syndromes of XXXX ].

@entity1 @entity2002 @entity2289 @entity556 @entity101 @entity2232 @entity5 @entity854 @entity8729 @entity1427 @entity3479
OBJECTIVE: To study the correlation between prethrombotic biomarkers and traditional Uyghur medicinal syndromes of @entity5 . METHODS: One hundred and fifty-nine @entity5 inpatients were randomly selected and typed according to traditional Uyghur medicine theories. The expressions of peripheral platelet membrane glucoprotein ( @entity1427 and @entity8729 ), levels of serum endothelin ( @entity2232 ), plasma @entity3479 ), plasminogen activator inhibitor ( @entity2289 ), plasma @entity2002 ( @entity2002 ), prothrombin time (PT), and @entity556 time (TT), and activated partial thromboplastin time (APTT) were detected by flow cytometry, radioimmunoassay, and enzyme-linked immunosorbent assay (ELISA) respectively. RESULTS: The @entity1 were typed as 68 of abnormal Savda syndrome, 34 of abnormal Khan syndrome, 31 of the @entity854 , and 26 of the @entity854 . Compared with the control group, the levels of @entity8729 , @entity2289 , and @entity2232 increased, levels of @entity2002 and @entity3479 decreased, PT prolongated and APTT shortened in the abnormal Savda group and the non-abnormal Savda group (including abnormal Khan, abnormal Sepra, and abnormal Belghem types) (all P < 0.05). No significant difference of @entity1427 or TT was shown in inter-group comparison (P > 0.05). Compared with abnormal Khan and Belghem groups, the @entity2232 level increased in the abnormal Savda group (P < 0.05). Compared with the abnormal Sepra group, the @entity8729 positive percentage increased in abnormal Savda group (P < 0.05). No significant difference in @entity1427 positive percentage, @entity3479 or @entity2289 contents, PT, TT, or APTT was shown in @entity1 of different traditional Uyghur medicine syndrome groups (P > 0.05). CONCLUSIONS: Prethrombotic changes existed in @entity5 @entity1 of different Uyghur abnormal syndrome types, manifested as injuries of vessel epithelial cells, platelet activation, @entity101 , lowered fibrinolytic function. The prethrombotic changes were more obviously seen in the abnormal Savda group.
