Spatial working XXXX in primary onset @entity6 : An ethology and BOLD-fMRI study.

@entity1 @entity6 @entity75 @entity73 @entity26 @entity3948 @entity4940 @entity71152 @entity2414 @entity413
PURPOSE: To explore mild @entity73 and/or spatial working @entity2414 in @entity1 with primary onset @entity6 (T2DM] using ethology (behavior tests) and blood @entity26 level-dependent functional magnetic resonance imaging (BOLD-fMRI). MATERIALS AND METHODS: Eighteen primary onset T2DM @entity1 and 18 matched subjects with normal blood @entity413 levels were all tested using the Montreal cognitive assessment scale test, the Wechsler Memory Scale Chinese-revised test, and scanned using BOLD-fMRI (1.5T, EPI sequence) while performing the n-back task to find the activation intensity of some cognition-related areas. RESULTS: The ethology results showed that T2DM @entity1 had a mild @entity73 and @entity2414 (P   <   0.05). The fMRI scan identified a neural network consisting of bilateral dorsolateral prefrontal cortex (DLPFC), bilateral premotor area (PreMA), bilateral parietal lobe (PA), and anterior cingulate cortex (ACC) / @entity4940 ( @entity4940 ) that was activated during the n-back task, with right hemisphere dominance. However, only the right PA and ACC/ @entity4940 showed a load effect via quantitative analysis in the T2DM group; the activation intensity of most working memory-related brain areas for the T2DM group were lower than for the control group under three memory loads. Furthermore, we found that the activation intensity of some cognition-related areas, including the @entity3948 , left caudate nucleus, and bilateral hippocampus/parahippocampal gyrus were lower than the control group under the memory loads. CONCLUSION: @entity6 -related @entity75 of primary onset middle-age T2DM @entity1 with right DLPFC-posterior parietal lobe and @entity71152 causes @entity73 and mild @entity73 .J. Magn. Reson. Imaging 2015.
