Long-term outcome in intensive care unit survivors after mechanical ventilation for XXXX .

@entity1 @entity204 @entity1779 @entity772
OBJECTIVE: To evaluate long-term survival and functional outcome in intensive care unit survivors after mechanical ventilation for @entity1779 . DESIGN: Retrospective chart review and prospective follow-up study. SETTING: Outpatient follow-up. @entity1 : Between 1997 and 2000, 120 @entity1 were mechanically ventilated for an @entity1779 at our intensive care unit. Sixty-two @entity1 were discharged from hospital (in-hospital mortality = 48%). Sixty @entity1 were evaluated for survival and functional outcome (two were lost to follow-up). Time between discharge and follow-up was > or =1 yr and was a mean of 27 +/- 14 months (range, 12-56). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: @entity1 ' physicians were first asked about survival, and @entity1 or proxies were interviewed by phone. Barthel Index and modified Rankin Scale scores were collected, and demographic information and general data were reviewed. The estimated life-table survival curve after discharge was 64.6% at 1 yr and 57% at 3 yrs. In the 24 @entity1 who died, the mean time between discharge and @entity204 was 5 +/- 6 months. Probability of @entity204 after discharge significantly increased if age at admission was >65 yrs (p <.01; odds ratio, 3.5; 95% confidence interval, 1.4-9.1) and if Glasgow @entity772 Scale score at discharge was <15 (p <.01; odds ratio, 3.9; 95% confidence interval, 1.6-9.5). In the 36 long-term survivors, Barthel Index was 67.5 +/- 15 (median +/- median absolute dispersion) and modified Rankin Scale score was 2.6 +/- 0.5. Fifteen @entity1 (42%) had a slight or no disability (Barthel Index > or =90 and modified Rankin Scale score < or =2), whereas 21 @entity1 (58%) had moderate or severe disability (Barthel Index < or =85 and modified Rankin Scale score >2). CONCLUSIONS: Probability of survival at 3 yrs after mechanical ventilation for an @entity1779 was >50%. Age was an important determinant of long-term survival. Forty-two percent of long-term survivors were independent for activities of daily living. Only a few long-term survivors had a very high degree of disability.
