Analysis of renal functions and XXXX in young obese adults.

@entity1 @entity644 @entity101 @entity28 @entity2299 @entity5052 @entity4854
OBJECTIVE: To investigate the prevalence of @entity28 in young adults and to analyze the influencing factors on renal functions and @entity644 in this population. METHODS: This study comprised civil servants between 20 and 39  years old, who received physical examinations at the First Affiliated Hospital of Fujian Medical University. The subjects were categorized into four groups based on age (20-24, 25-29, 30-34 and 35-39  years) and the number of risk factors they had ( @entity101 , @entity2299 , @entity4854 and @entity5052 ). The relationships between @entity28 and the prevalence of @entity644 , between @entity28 and risk factors and between estimated glomerular filtration rate (eGFR) and @entity644 were analyzed. RESULTS: Among the 2293 young civil servants, in @entity1 the prevalence of @entity28 was 33.3  % and @entity644 was 2.5  %. However in @entity1 the prevalence of @entity28 and @entity644 was 7.5  % and 1.7  %, respectively. The levels of blood pressure, serum uric acid (UA), cholesterol (TC), triglyceride (TG), fasting glucose (FBG) and low-density lipoprotein cholesterol (LDL-C) were lower and the level of serum high-density lipoprotein cholesterol (HDL-C) was higher in nonobese groups compared with obese groups. There were no significant differences in eGFR between the two groups. The eGFR in male subjects was associated with age, UA, body mass index (BMI), FBG, TC, TG, LDL and HDL, and in female subjects associated with UA, age, BMI, diastolic blood pressure, FBG and LDL. BMI in both males and females increased with the higher number of risk factors. Multiple regression analysis revealed that @entity101 , @entity2299 , @entity4854 and @entity5052 were independently associated with @entity28 . eGFR decreased with a higher number of risk factors. Obesity, blood pressure, @entity2299 , @entity4854 and @entity5052 were independently associated with @entity644 . CONCLUSION: Obesity can pose an independent risk factor for @entity644 in young adults. @entity101 , @entity2299 , @entity4854 and @entity5052 were independently associated with @entity28 . eGFR decreased with a higher number of risk factors.
