Clinical spectrum of XXXX .

@entity1 @entity459 @entity788 @entity2741 @entity174 @entity5 @entity170 @entity425 @entity2001 @entity2742 @entity79 @entity615 @entity1290 @entity121
OBJECTIVE: @entity459 (1HPT) is now being diagnosed with increasing frequency. Simultaneously there has been an apparent change in the presentation of the disease and indications for surgery. The aim of this study was to examine the clinical presentation, indications for surgery, and outcomes of neck explorations for @entity459 . METHODS: This study was carried out over a 12 year period, January 1990 to April 2002 at Jordan University Hospital, Amman, Jordan. Information on the indications, procedure performed, pathology and complications of all neck explorations for 1HPT was obtained from a retrospective thyroid/parathyroid surgical database. A minimum of 12 months follow-up was required in order to determine outcome of surgery. RESULTS: Out of 40 @entity1 diagnosed with @entity459 at Jordan University Hospital, Amman, over 12 years, 14 @entity1 (35%) diagnosed 4 years after the onset of their disease. Severe @entity79 was the main indication for surgery in 28 @entity1 ; 5 @entity1 with fractured bones, 2 @entity1 with @entity2001 , 3 @entity1 with @entity5 and severe @entity170 and @entity615 in 22 @entity1 ; @entity1290 in 10 @entity1 ; @entity121 and @entity425 in 14 @entity1 ; acute @entity788 in one @entity1 and asymptomatic @entity2742 following biochemical screening in one @entity1 . Two @entity1 continued to have persistent @entity2741 after the first operation; one of them has been cured by reoperation for an ectopic parathyroid in the anterior mediastinum resulting in an overall cure rate of 97.5%. CONCLUSION: This study showed that severe @entity79 with @entity174 , @entity2001 and @entity5 are still the most common presentation of @entity459 in Jordan; this is most likely due to delay in diagnosis and initiation of treatment. It is important to screen for @entity2742 in high risk @entity1 and to refer these @entity1 to specialized centers for proper management.
