Paraoxanase as an indicator of myocardial ischemia and its utility in determining extension of XXXX .

@entity1 @entity583 @entity63
BACKGROUND: The aim of this study was to investigate Paraoxanase 1 (PON-1) activity in @entity1 with ST-elevated and non-ST-elevated @entity583 ( @entity583 ) and to determine its correlation with Gensini scores (GSs). METHODS: A total of 109 @entity1 with @entity583 and 58 healthy subjects as control group were included in the study. @entity1 were divided into 2 subgroups as ST-elevated and non-ST-elevated @entity583 @entity1 (Group I and II, respectively). Controls were named as Group III. PON-1 activity was determined on admission to emergency department for each group. In addition, GSs for @entity1 groups were determined. Then, groups were compared according to their results. RESULTS: PON-1 levels in Group I and II were significantly lower when compared to Group III. Median GSs for Group I and II were 60 and 64, respectively. The cut-off value of PON-1 for diagnosis of @entity583 was  <=180 U/L, which was identified by receiver characteristics receiver curve analysis. However, we could not determine a significant relationship between serum PON-1 levels and GSs in @entity1 with @entity583 . CONCLUSION: PON-1 levels measured on admission to emergency department may be used to rule out @entity583 . PON-1 levels in @entity583 @entity1 are found to be inefficient in determining extension of @entity63 measured by GS.
