The efficacy of oral appliances in the treatment of XXXX .

@entity101 @entity27 @entity1697 @entity387
OBJECTIVES: The purpose of this study is to evaluate the efficacy of @entity1697 ( @entity1697 ) treatment for subjects with @entity27 ( @entity27 ) and to determine the dental parameters associated with treatment outcomes. STUDY DESIGN: This study uses a prospective longitudinal design. METHODS: Consecutive Chinese subjects with severe @entity27 who refused continuous positive airway pressure treatment were recruited. Their dental measurements were taken from lateral cephalometric radiographs. Polysomnograms with @entity1697 were repeated at 3 months and 1 year. Blood pressure was taken in the morning after sleep studies. RESULTS: Thirty-four subjects were evaluated at 3 months and 1 year according to the principle of intention-to-treat analysis. @entity1697 reduced AHI significantly in subjects with favorable responses, from 49.3 (37.4-67) to 12.5 (6.1-15.7), p   <   0.001 at 3 months and from 47.5 (41.1-72.9) to 13.1 (6.0-14.0), p   <   0.001 at 1 year. These @entity27 subjects had an increased overjet at baseline compared to those with unfavorable responses (p    <=   0.05). Systolic blood pressure was significantly reduced in those @entity101 @entity27 subjects after 3 months and 1 year of treatment. CONCLUSIONS: @entity1697 reduces the severity of @entity387 , and the effect is maintained at 1 year in subjects with retrognathism. @entity1697 appears to reduce systolic blood pressure in @entity101 @entity27 subjects at 3 months and 1 year.
