@entity1252 complicated with femoral XXXX treated by Chinese medicine therapy for activating blood and dredging collaterals method.

@entity1 @entity32 @entity1252 @entity887 @entity2738
OBJECTIVE: To observe the effect and mechanism of Chinese medicine therapy for activating blood and dredging collaterals (ABDC) on treating @entity1252 complicated with @entity2738 (SLE-ANFH). METHODS: Thirty-four @entity1 (51 joints) with SLE-ANFH were assigned by a random number table to two groups: 22 @entity1 (32 joints) in the treatment group and 12 @entity1 (19 joints) in the control group. All received Western medical conventional treatment for anti- @entity32 and immunosuppression, but an additional Chinese medicine decoction prescribed based on ABDC principle was administered to @entity1 in the treatment group. The observation on the @entity1 ' condition and therapeutic effect lasted for 3 years. RESULTS: The @entity1 ' conditions in the two groups, as assessed by Association for Research Circulation Osseous (ARCO) staging, were similar before treatment. After treatment, comparison between groups showed significant difference (P<0.05), and the raised Harris functional scores in the treatment group were higher than that in the control group (P<0.01). The post-treatment symptom improving rate in the treated group was 72.73%, which was higher than that in the control group (50.00%, P<0.05). Moreover, the former was superior in improving hematologic and hemorrheologic parameters in terms of prolonging activated partial thromboplastin time, lowering whole blood middle/low shear viscosity, and plasma viscosity (P<0.05 or P<0.01). Two @entity1 in the control group but none in the treatment group received hip joint replacement operation during the observation period. CONCLUSIONS: Chinese medicine ABDC therapy could effectively alleviate clinical symptoms and improve joint function of @entity1 with SLE-ANFH. The mechanism may be related to its effects on improving high coagulation manner and trend for getting @entity887 .
