Prevalence of cardiovascular risk factors in youth with type 1 XXXX and elevated body mass index.

@entity1 @entity101 @entity28 @entity6 @entity2299
AIM: The prevalence of cardiovascular risk factors in @entity1 with type 1 @entity6 and elevated BMI in the USA is poorly defined. We aimed to test the hypothesis that @entity1 with type 1 @entity6 who are overweight or @entity28 have increased frequencies of @entity101 , @entity2299 , and micro-/macroalbuminuria compared to their healthy weight peers. METHODS: We studied 11,348 @entity1 2 to <18  years of age enrolled in T1D Exchange between September 2010 and August 2012 with type 1 @entity6 for >= 1  year and BMI  >=   5th age-/sex-adjusted percentile (mean age 12  years, 49  % female, 78  % non-Hispanic White). Overweight and @entity28 were defined based on Centers for Disease Control and Prevention criteria. Diagnoses of @entity101 , @entity2299 , and micro-/macroalbuminuria were obtained from medical records. Logistic and linear regression models were used to assess factors associated with weight status. RESULTS: Of the 11,348 @entity1 , 22  % were overweight and 14  % @entity28 . @entity101 and @entity2299 were diagnosed in 1.0  % and 3.8  % of @entity1 , respectively; micro-/macroalbuminuria was diagnosed in 3.8  % of @entity1 with available data (n  =  7,401). The odds of either @entity101 or @entity2299 were higher in @entity28 than healthy weight @entity1 [OR 3.5, 99  % confidence interval (CI) 2.0-6.1 and 2.2, 99  % CI 1.6-3.1, respectively]. Obese @entity1 tended to be diagnosed with micro-/macroalbuminuria less often than healthy weight @entity1 (OR 0.6, 99  % CI 0.4-1.0). CONCLUSIONS: Obese @entity1 with type 1 @entity6 have a higher prevalence of @entity101 and @entity2299 than healthy weight @entity1 with type 1 @entity6 . The possible association of @entity28 with lower micro-/macroalbuminuria rates warrants further investigation.
