Effect of low-dose @entity786 on @entity1642 and inflammatory reaction of acute XXXX reperfusion injury.

@entity32 @entity8 @entity5721 @entity13841 @entity19 @entity786 @entity8024 @entity1642
OBJECTIVE: To explore the effect of low-dose @entity786 (CP) on @entity1642 ( @entity1642 ) and inflammatory reaction of acute @entity8 reperfusion injury (IRI), providing new ideas for clinical treatment. MATERIALS AND METHODS: Sixty healthy adult male @entity19 were selected and divided randomly into sham operation group (n = 20), IRI group (n = 20 cases), and the experimental group (n = 20 cases). @entity19 in the experimental group were pretreated with low-dose CP and @entity5721 . @entity8024 ( @entity8024 ) immunohistochemical staining was conducted after the 24h and the detection of @entity13841 protein by Western blot method. Postoperative 3h and 7 day survival rate, the results of @entity8024 immunohistochemistry staining and the gray values of @entity13841 ( @entity13841 ) of @entity19 were compared between the three groups. RESULTS: The survival rates of @entity19 in the IRI group and the experimental group after operation were decreased significantly (p < 0.05). However, the survival rates of @entity19 in the experimental group were higher than that in the IRI group. The differences were significant (p < 0.05). The expression of @entity8024 was significantly reduced (p < 0.05). The difference was statistically significant. The expression of @entity8024 was significantly reduced (p < 0.05). The gray values of @entity19 in the IRI group and the experimental group were significantly increased. The difference was statistically significant (p < 0.05). And the gray value in the IRI group increased more than that of the experimental group. The difference was statistically significant (p < 0.05). CONCLUSIONS: The pretreatment with low-dose CP for @entity19 with acute renal IRI can reduce effectively the @entity1642 and @entity32 , which reduces @entity8 for @entity19 and have good effect on prolonging its life. It provides a good way for the guidance of clinical research.
