Effect of Jyoti   mat   seed oil on spatial and fear memory using XXXX induced amnesia in @entity19 .

@entity303 @entity19 @entity195 @entity5591 @entity2414 @entity2475
BACKGROUND: Treatment of @entity2414 associated with @entity303 such as @entity195 is still inadequate and requires development of new drugs. OBJECTIVE: The objective was to evaluate the memory enhancing effect of Celastrus paniculatus seed oil. MATERIALS AND METHODS: C. paniculatus seed oil was mixed with equal amount of pure ghee and administered orally to @entity19 in the dose of 200 mg/kg/day. @entity2475 was used as a standard nootropic. Elevated plus maze and passive avoidance tests were used as a models to test spatial and fear memory respectively. @entity5591 (3 mg/kg, i.p.), was used as an amnestic agent. RESULTS: @entity19 receiving C. paniculatus showed significant memory enhancement as compared to @entity5591 group. The effect of C. paniculatus and combination of C. paniculatus with @entity2475 was comparable to that with @entity2475 alone. CONCLUSION: The present study demonstrates that C. paniculatus seed oil has memory enhancing effect and hence can be developed as a potential drug in the treatment of @entity303 .
