Thyroid Function and Thyroid Autoimmunity in Relation to Weight Status and Cardiovascular Risk Factors in XXXX and Adolescents: a Population-Based Study.

@entity1 @entity1496 @entity28 @entity1955 @entity7287 @entity792 @entity65
OBJECTIVE: In @entity28 subjects, slight increases have been observed in thyrotropin (TSH), but data in @entity1 are scarce. We aim to evaluate whether thyroid function and @entity792 vary with weight status in a healthy population of @entity1 and adolescents and to determine whether hyperthyrotropinemia is associated with any @entity65 factor. METHODS: Cross-sectional epidemiological study in Almer  a (Spain). Representative sample of 1317 healthy subjects aged 2-16 years. Thyroid function, thyroid @entity792 and @entity65 factors were measured. Statistical tests: chi-square, analysis of variance and multiple linear regression. RESULTS: The @entity28 @entity1 and adolescents had thyrotropin levels (mean (standard deviation)) of 3.12 (2.44) mU/L. These levels were higher than those of the subjects with overweight, 2.79 (1.51), and normal weight, 2.73 (1.30), (p=0.02). Levels of free @entity1955 and urinary @entity1496 did not differ significantly between the groups. The prevalence (percentage (95% confidence interval)) of thyroid @entity792 was lower in the individuals with normal weight, 2.9% (2.0-4.2), than in those with overweight, 6.3% (3.9-9.9), and @entity28 , 5.6% (2.5-11.3) (p=0.02). TSH levels were associated with @entity28 (b=0.36; p<0.001) and thyroid @entity792 (b=1.10; p<0.001). Nevertheless, they were not associated with any @entity65 factor. CONCLUSION: The @entity28 @entity1 and adolescents had higher levels of @entity7287 than those with overweight and normal weight. These differences were of very little clinical significance, and are accounted in part for by the higher prevalence of thyroid @entity792 in these subjects. This hyperthyrotropinemia was not associated with any @entity65 factor.
