Cardiovascular function of African XXXX with different BMIs and blood pressures: the POWIRS study.

@entity1 @entity551 @entity101 @entity65
INTRODUCTION: The aim of this study was to investigate the cardiovascular profiles of a group of African @entity1 with different body mass indices and blood pressures. MATERIALS AND METHODS: The study included a sample of 98 apparently healthy African @entity1 . The subjects were divided into three groups: lean normotensive (lean NT), overweight/obese normotensive (OW/OB NT), and overweight/obese @entity101 (OW/OB @entity101 ). The Finometer apparatus was used to obtain a more elaborate cardiovascular profile. The lipid profile and subcutaneous fat distributions were also determined. RESULTS: A positive correlation between blood pressure and increased adiposity was obtained. Cardiac output (CO) was elevated in both OW/OB groups. Arterial compliance (CW) was significantly decreased and total peripheral resistance (TPR) significantly increased in the OW/OB @entity101 group compared to the OW/OB NT group. In the total group, @entity551 could be explained best by the abdominal skinfold, which showed a direct positive association with TPR and a negative association with CW . In the OW/OB @entity101 group, the increased TPR could best be explained by the abdominal skinfold. CONCLUSIONS: In the OW/OB @entity101 group, an increase in CO and decrease in vascular function led to the @entity101 of this group. This seems to be related to a truncal, especially abdominal subcutaneous fat distribution. The decreased vascular function was reaffirmed by the pulse pressure (PP) exceeding 63 mmHg, indicating that this group was at high risk for the development of further @entity65 . Lack of significant differences between the OW/OB groups for the anthropometric and lipid profile variables and the difference in age may indicate that the younger OW/OB NT group was at high risk and should be followed up in ensuing years.
