Multidrug resistant XXXX isolates from a teaching hospital.

@entity1 @entity2892 @entity14116 @entity18255 @entity3064 @entity4509 @entity869 @entity5899 @entity5646 @entity3399
Abstract @entity3064 is the most common nosocomial pathogen among all @entity3064 spp. A. baumannii tend to be resistant to multiple antibiotics, and represent a severe threat in the treatment of hospitalized @entity1 . The purpose of this study was to evaluate the prevalence, biotyping, and antibiotic resistance status of A. baumannii isolates recovered from submitted hospital clinical specimens. The in-vitro activity of 29 currently used antimicrobial agents was studied in 180 isolates of A. baumannii. The prevalence was higher in wound exudates (32%) and urine samples (22%) than in other specimens. Forty-six percent of the isolates were of biotype 9. The evolution of resistance from November 1996 through October 1998 was studied. More than 75% of the isolates were multidrug resistant (MDR) and more than 70% were #-lactamase producers. @entity4509 , @entity869 + @entity5899 , and @entity2892 are still effective antimicrobial agents, but a steady rise in the values of the minimum inhibitory concentration at which 50% of the isolates were inhibited (MIC50 )and MIC90 was observed. Resistance to @entity5646 (60%), @entity14116 (60%), @entity2892 (29%), @entity3399 (73%), and @entity18255 (25%) was noted; @entity14116 and @entity18255 are not generally used in this hospital. From the findings of the present study, no single drug appears to be suitable for empirical therapy for this nosocomial pathogen. Abstract @entity3064 is the most common nosocomial pathogen among all @entity3064 spp. A. baumannii tend to be resistant to multiple antibiotics, and represent a severe threat in the treatment of hospitalized @entity1 . The purpose of this study was to evaluate the prevalence, biotyping, and antibiotic resistance status of A. baumannii isolates recovered from submitted hospital clinical specimens. The in-vitro activity of 29 currently used antimicrobial agents was studied in 180 isolates of A. baumannii. The prevalence was higher in wound exudates (32%) and urine samples (22%) than in other specimens. Forty-six percent of the isolates were of biotype 9. The evolution of resistance from November 1996 through October 1998 was studied. More than 75% of the isolates were multidrug resistant (MDR) and more than 70% were #-lactamase producers. @entity4509 , @entity869 + @entity5899 , and @entity2892 are still effective antimicrobial agents, but a steady rise in the values of the minimum inhibitory concentration at which 50% of the isolates were inhibited (MIC50) and MIC90 was observed. Resistance to @entity5646 (60%), @entity14116 (60%), @entity2892 (29%), @entity3399 (73%), and @entity18255 (25%) was noted; @entity14116 and @entity18255 are not generally used in this hospital. From the findings of the present study, no single drug appears to be suitable for empirical therapy for this nosocomial pathogen.
