[ XXXX with normal coronary vessels: an association with dysfunction of the coronary microcirculation].

@entity1 @entity662 @entity3361 @entity880 @entity583
The association of @entity583 ( @entity583 ) with normal coronary arteries was analyzed prospectively. A series of 128 consecutive @entity1 underwent coronary angiography within 1 week from @entity583 . Seven @entity1 , all females, had no coronary artery lesions and were considered eligible for the study. All 7 @entity1 underwent atrial pacing (10 g/min increments every 2 min), ergonovine testing (E; total dose 0.650 mg i.v.). Great cardiac vein flow (GCVF; thermodilution technique), mean aortic pressure (MAP), anterior coronary resistance (ACR) and myocardial @entity880 extraction [(Lac art-Lac gcv)/Lac art] were measured at baseline and during testing. Pacing-induced typical @entity662 occurred in 5 @entity1 : 4 of them showed concurrent significant (> or = 0.15 mV) ST downsloping. At peak pacing, GCVF increased only by < 50%, or even decreased, in all @entity1 . Baseline @entity880 extraction (0.13 +/- 0.11) changed to @entity880 production (-0.15 +/- 0.10) in 7/7 @entity1 . None of the @entity1 showed focal @entity3361 following E. During testing, however, all 7 @entity1 showed decrease in GCVF (110 +/- 47 versus 74 +/- 21; p < 0.005), increase in ACR (0.92 +/- 0.29 versus 1.43 +/- 0.20; p < 0.001), and significant coronary @entity880 production (-0.18 +/- 0.12). Six @entity1 referred slight to moderate @entity662 , which was accompanied by ST downsloping in 4.(ABSTRACT TRUNCATED AT 250 WORDS)
