[Locoregional recurrences after conservative surgery in early XXXX ].

@entity1 @entity66 @entity7279 @entity0 @entity5
INTRODUCTION: Conservative surgery is considered as standard and alternative mastectomy in early stage @entity0 but number of local recurrence is higher. Aim of the study was to detect number of local recurrences after conservative surgery and to identify risk factors of local recurrence especially importance of resection margins. MATERIALS AND METHODS: Local recurrences were evaluated in @entity1 after conservative surgery in early @entity0 at department of surgery Atlas hospital in Zlin between January 2004 and December 2008. @entity7279 (only one T3) @entity0 were included in study. Diagnostic biopsy, lumpectomy and quadrantectomy were performed. In all @entity1 axillary nodes were examined. Study guidelines required microscopic distance between resection line and @entity5 margin 5mm. Specimen after surgery was marked with black ink and from June 2006 with six colors ink. Radiotherapy and chemotherapy in additions to character of @entity5 followed surgery. RESULTS: Conservative surgery was performed in 330 @entity1 . Mean age was 59 years. Follow-up was 39.6 month. Stage of the @entity5 : 0 19x, I 101x, IIA 163x, IIB 33x, IIIA 5, IIIB 0, IIIC 9. Lumpectomy was made 11 lx including 11 diagnostic biopsies and quadrantectomy 219x. Final conservative surgery was 331x and mastectomy 19x. Positive axillary nodes were 98x. In breast local recurrence appeared in 5 (3.6%) @entity1 and one had regional recurrence without in breast recurrence. Distant metastases were 8x (2.4%) and ten @entity1 died on @entity66 without locoregional recurrence. CONCLUSION: Local recurrence appeared only 5x. Clear margins after breast conserving surgery are very important factor in prevention local recurrence. We recommend keeping 5 mm resection distance.
