The first 2 years of XXXX screening in Ferrara, Italy.

@entity1 @entity1127 @entity5 @entity4620 @entity1892 @entity14 @entity652
We report on the first screening round in the District of Ferrara, a region of Emilia-Romagna, carried out between March 2005 and March 2007 to illustrate the effort of @entity14 ( @entity14 ) screening from administration and information to therapy and follow-up. After invitation of 38 344 @entity1 aged 50-69 years (28.5%), 19 480 (50.8%) accepted the immunological faecal occult blood test, with 1 149 (6%) resulting positive. One thousand and one individuals (88.2%) who tested positive for immunological faecal occult blood test accepted examination by either colonoscopy (99.5%) or barium enema (0.5%). Out of 996 screenees having a colonoscopy, 231 had low-risk @entity652 (23.2%) and 239 had high-risk @entity652 (24%), and were treated endoscopically (96%) or surgically (4%). Ninety-one @entity5 were diagnosed in 9.1% of colonoscopies (Dukes stadia: A, 58.2%; B, 19.8%; C, 18.7%; D, 3.3%). @entity5 (all in @entity1127 ) were treated endoscopically, and the remaining 77 were treated by surgery. One @entity1892 @entity1 and 13 of 17 Dukes C @entity1 received adjuvant chemotherapy. Three @entity4620 @entity1 had chemotherapy only. During the 2-year study period, 87 screenees had a follow-up colonoscopy: no @entity5 was found in 35 @entity1 initially diagnosed with @entity5 ; low-risk @entity652 were found in 31 of 52 @entity1 with initial high-risk @entity652 . In conclusion, the first @entity14 screening round in Ferrara was easy to organize, had a high acceptance, and detected 91 @entity5 (78% of which were in Dukes stages A and B, compared with only 40% in sporadic @entity14 in the same background population). Chemotherapy was necessary in 17 cases. This report may motivate other health authorities to initiate @entity14 screening campaigns.
