Retinal nerve fiber layer and ganglion cell complex thicknesses measured with spectral-domain optical coherence tomography in eyes with no light perception due to XXXX .

@entity1 @entity1952 @entity7995 @entity735 @entity1781
PURPOSE: To measure retinal nerve fiber layer thickness (RNFLT) and @entity735 with no light perception due to @entity1781 using spectral-domain optical coherence tomography. METHODS: Fourteen eyes of 14 @entity1 (9 @entity1 , 5 @entity1 ; mean age 56.0    16.6 (standard deviation)  years] with no light perception due to @entity1781 were recruited to this retrospective study. Only clinically stable eyes were included. Eyes were imaged at least 6  months after the onset of the disease. Five @entity1 lost light perception due to @entity1781 , four @entity1 had @entity1781 , two @entity1 had @entity7995 , two @entity1 had @entity1781 , and one @entity1 had @entity1952 . Global and quadrant RNFLTs were measured with the Cirrus HD-optical coherence tomography (OCT) system; global and hemisphere GCCTs were measured by spectral-domain OCT (RTVue OCT system). Only reliable OCT images were used for further analysis. RESULTS: Reliable RNFL images were obtained in 12 eyes, and reliable GCC images were obtained in 11 eyes. Global, superior, temporal, inferior, and nasal RNFLT were 57.5      6.7, 60.6      7.6, 54.1      11.2, 59.7      9.5, and 55.6      7.4    m, respectively. Global, superior, and inferior GCC thicknesses were 68.8      9.6, 70.7      12.2, and 67.8      8.8    m, respectively. CONCLUSIONS: A considerable proportion of RNFL and GCC remained in eyes with no light perception vision. Clinicians should take this into account when evaluating the severity of @entity1781 from OCT-measured RNFLT and GCCT.
