Autologous Blood and Platelet Rich Plasma Injections in the Treatment of XXXX : A Critically Appraised Topic.

@entity1 @entity32 @entity924 @entity158
UNASSIGNED: @entity924 is a @entity158 commonly affecting the general and athletic population and presents with @entity158 , stiffness, and swelling in the mid-portion of the Achilles tendon. The physical stress placed on the tendon results in micro-trauma, which leads to subsequent @entity32 and degeneration. While it is not surprising that this condition affects the physically active, nearly one third of @entity924 cases occur in sedentary individuals. Etiology for this condition stems from a change in loading patterns and/or overuse of the tendon, thus resulting in microscopic tearing and degenerative changes. There are numerous causes contributing to the maladaptive response in these @entity1 , such as mechanical, age-related, genetic and vascular factors. The treatment for these @entity1 is typically load management and eccentric strengthening of the gastroc-soleus complex. Unfortunately, conservative treatment can lead to surgical intervention in up to 45% of cases. A relatively new phenomenon in the treatment of this condition is the use of autologous blood injections (ABI) and platelet-rich plasma injections (PRPI). This need for a less invasive treatment fostered more investigation into ABI and PRPI to treat these non-responsive @entity1 . However, the evidence concerning the effectiveness of these treatments in @entity1 with @entity924 has not been synthesized.
