Impact of adjuvant treatment modalities on survival outcomes in curatively resected XXXX .

@entity1 @entity1817 @entity788 @entity1349
BACKGROUND: We examined the impact of adjuvant modalities on resected @entity788 (PAC). METHODS: A total of 563 @entity1 who were curatively resected for PAC were retrospectively analyzed between 2003 and 2013. RESULTS: Of 563 @entity1 , 472 received adjuvant chemotherapy (CT) alone, chemoradiotherapy (CRT) alone, and chemoradiotherapy plus chemotherapy (CRT-CT) were analyzed. Of the 472 @entity1 , 231 were given CRT-CT, 26 were given CRT, and 215 were given CT. The median @entity1349 ( @entity1349 ) and @entity1349 ( @entity1349 ) were 12 and 19 months, respectively. When CT and CRT-CT groups were compared, there was no significant difference with respect to both @entity1349 and @entity1349 , and also there was no difference in @entity1349 and @entity1349 among CRT-CT, CT and CRT groups. To further investigate the impact of radiation on subgroups, @entity1 were stratified according to lymph node status and resection margins. In node-positive @entity1 , both @entity1349 and @entity1349 were significantly longer in CRT-CT than CT. In contrast, there was no significant difference between groups when @entity1 with node-negative disease or @entity1 with or without positive surgical margins were considered. CONCLUSIONS: Addition of radiation to CT has a survival benefit in @entity1 with @entity1817 following pancreatic resection.
