Integrated cooling-vacuum-assisted 1540-nm erbium:glass laser is effective in treating mild-to-moderate XXXX .

@entity1 @entity5477 @entity10974 @entity75 @entity158
UNASSIGNED: Acne treatment by a mid-infrared laser may be unsatisfactory due to deeply situated acne-affected sebaceous glands which serve as its target. Skin manipulation by vacuum and contact cooling may improve laser-skin interaction, reduce @entity158 sensation, and increase overall safety and efficacy. To evaluate the safety and efficacy of acne treatment using an integrated cooling-vacuum-assisted 1540-nm erbium:glass laser, a prospective interventional study was conducted. It included 12 @entity1 (seven @entity1 and five @entity1 ) suffering from mild-to-moderate @entity5477 . The device utilizes a mid-infrared 1540-nm laser (Alma Lasers Ltd. Caesarea, Israel), which is integrated with combined cooling-vacuum-assisted technology. An @entity75 is initially manipulated upon contact by a vacuum-cooling-assisted tip, followed by three to four stacked laser pulses (500-600  mJ, 4  mm spot size, and frequency of 2  Hz). @entity1 underwent four to six treatment sessions with a 2-week interval and were followed- @entity10974  months after the last treatment. Clinical photographs were taken by high-resolution digital camera before and after treatment. Clinical evaluation was performed by two independent dermatologists, and results were graded on a scale of 0 (exacerbation) to 4 (76-100  % improvement). @entity1 ' and physicians' satisfaction was also recorded. @entity158 perception and adverse effects were evaluated as well. All @entity1 demonstrated a moderate to significant improvement (average score of 3.6 and 2.0 within 1 and 3  months, respectively, following last treatment session). No side effects, besides a transient erythema, were observed. Cooling-vacuum-assisted 1540-nm laser is safe and effective for the treatment of @entity5477 .
