Intestinal spirochetosis in homosexual XXXX .

@entity1 @entity1944 @entity2954 @entity6368 @entity575 @entity1711 @entity1710
Previous studies have demonstrated @entity1944 in rectal biopsy specimens from 2 to 7 percent of heterosexual and 36 percent of homosexual @entity1 , but the role of @entity1944 in the pathogenesis of @entity1944 remains unclear. To assess the clinical, histologic, and microbiologic correlates of @entity1944 in a high-risk group, rectal biopsy specimens from 130 homosexual @entity1 , 92 percent of whom had intestinal symptoms, were evaluated. All @entity1 were extensively evaluated for rectal and enteric pathogens. Intestinal spirochetosis was identified in rectal biopsy specimens from 39 (30 percent) @entity1 ; 15 percent of biopsy specimens revealed @entity1944 on @entity1710 and @entity1711 plus alcian blue staining, and positive results were found in 30 percent on @entity575 staining. No rectal biopsy specimens from 79 control @entity1 with a variety of gastrointestinal symptoms demonstrated evidence of spirochetosis on @entity1710 and @entity1711 , alcian blue, or @entity575 staining (p less than 0.0001). Fifty-six percent of rectal biopsy specimens from @entity1 with @entity1944 were normal, and no specific histologic abnormality was correlated with @entity1944 . There were no differences in the presence of or type of intestinal symptoms, sigmoidoscopic appearance of the mucosa, type of sexual practice, or prior antibiotic use in @entity1 with and without spirochetosis. Other intestinal pathogens were frequent in both groups, and only @entity2954 was significantly associated with @entity1944 . It is concluded that homosexual @entity1 with intestinal symptoms have an increased prevalence of spirochetosis, often in association with @entity6368 . Independent association of spirochetosis with clinical or histologic findings could not be demonstrated.
