Low-protein diets affect ileal XXXX digestibility and gene expression of digestive enzymes in growing and finishing @entity1707 .

@entity3534 @entity1707 @entity1568 @entity1131 @entity2569 @entity4022 @entity71546 @entity1017 @entity2596 @entity3918 @entity815 @entity3689
The objective of this study was to evaluate effects of dietary @entity1131 ( @entity1131 ) intake on ileal @entity3689 digestibilities and expression of genes for digestive enzymes in growing and finishing @entity1707 . In Experiment 1, 18 growing @entity1707 (average initial BW = 36.5 kg) were assigned randomly into one of three treatments (n = 6/treatment group) representing normal (18 % @entity1131 ), low (15 % @entity1131 ), and very low (12 % @entity1131 ) protein intake. In Experiment 2, 18 finishing @entity1707 (average initial BW = 62.3 kg) were allotted randomly into one of three treatments (n = 6/treatment group), representing normal (16 % @entity1131 ), low (13 % @entity1131 ) and very low (10 % @entity1131 ) protein intake. In both experiments, diets with low and very low @entity1131 were supplemented with crystalline @entity3534 to achieve equal content of standardized ileal digestible Lys, Met, Thr, and Trp, and were provided to @entity1707 ad libitum. Daily feed intake, BW, and feed/gain ratios were determined. At the end of each experiment, all @entity1707 were slaughtered to collect pancreas, small-intestine samples, and terminal ileal chymes. Samples were used for determining expression of genes for digestive enzymes and ileal @entity3689 digestibilities. Growing @entity1707 fed the 12 % @entity1131 and 15 % @entity1131 diets had lower final body weight (P < 0.01) and ADG (P < 0.0001) when compared with @entity1707 fed the 18 % dietary @entity1131 diet. Growing @entity1707 fed with the 12 % @entity1131 diet showed higher digestibilities for @entity1131 (P < 0.05), @entity3918 (P < 0.05), Lys (P < 0.0001), Met (P < 0.01), @entity2569 (P < 0.01), Thr (P < 0.01), Trp (P < 0.05), @entity2596 (P < 0.05), @entity815 (P < 0.05), Ala (P < 0.05), @entity2569 (P < 0.01), and @entity4022 (P < 0.05) than those fed the 18 % @entity1131 diet. Finishing @entity1707 fed the 16 % @entity1131 diet had a higher (P < 0.01) final body weight than those fed the 10 % @entity1131 diet. mRNA levels for digestive enzymes ( @entity71546 , chymotrypsin B, and dipeptidases-II and III) differed among the three groups of @entity1707 (P < 0.05), and no difference was noted in the genes expression between control group and lower @entity1131 group. These results indicated that a reduction of dietary @entity1131 by a six-percentage value limited the growth performance of growing-finishing @entity1707 and that a low-protein diet supplemented with deficient @entity3534 could reduce the excretion of @entity1568 into the environment without affecting @entity1017 .
