Detection of human papillomavirus in esophageal and XXXX : A retrospective study by real-time polymerase chain reaction in an instutional experience from Turkey and review of literature.

@entity1 @entity5 @entity957 @entity281 @entity1800 @entity418 @entity285 @entity105 @entity420
UNASSIGNED: @entity418 is a poor-prognosis malignancy that ranks eighth among all @entity5 types, and its prevalence shows differences among geographical regions. Although the most important risk factors for @entity418 are @entity285 and smoking, @entity1800 , particularly @entity281 , are also considered among etiological agents. Our study aims to detect the presence of @entity418 in our @entity1 population and to investigate its correlation with clinico-pathological parameters. We investigated the presence of HPV-DNA by real-time polymerase chain reaction in a total of 52 @entity1 with @entity418 . Subtype analysis was performed in positive cases and was correlated with selected clinico-pathological parameters. Five (9.6%) of 52 @entity5 samples, 3 @entity957 (3/33 cases) and 2 @entity420 (2/19 cases), were HPV-DNA-positive. Subtype analysis could be performed in four HPV-DNA-positive cases, of which three were HPV type-39 and 1 was type-16. The Marmara region, where the present study was carried out, is a region with low-moderate risk for @entity418 , and the prevalence of HPV-DNA in these @entity5 is similar to the prevalence of HPV-DNA reported in the literature for regions with similar risk. In conclusion, we detected HPV DNA in a subset of esophageal and @entity5 . @entity281 may have a role in esophageal @entity105 and high-risk HPV subtypes can particularly be considered among risk factors since the prevalence of high risk @entity281 has also been found to be increased in regions with a high risk for @entity418 compared to low-moderate risk regions.
