Quantification of @entity2657 After XXXX .

@entity1545 @entity1 @entity2657 @entity510 @entity12432
BACKGROUND: @entity2657 ( @entity2657 ) is a manifestation of early @entity1545 (EBI) after @entity510 ( @entity510 ) and is an independent risk factor for poor outcome. The lack of a quantitative method to measure @entity2657 limits the study of its pathophysiology. The goal of this study is to develop a quantitative surrogate marker that represents @entity2657 after @entity510 . METHODS: @entity1 with spontaneous @entity510 were enrolled into a prospective observational database. Initial CT scans were graded for @entity2657 using established qualitative criteria. Selective sulcal volume ( @entity12432 ) was defined as total mL of sulcal volumes on axial CT slices above the most cranial section of the lateral ventricles to the last visible section. Using a semiautomatic threshold approach, sulcal regions were traced out with manual adjustments when necessary. The volume of sulci in each slice was calculated and multiplied by the slice thickness and number of slices to calculate the @entity12432 . All volumetric analysis was performed using Medical Image Processing, Analysis and Visualization Version 7.0.1 (MIPAV). RESULTS: A total of 109 subjects were included in our analysis. Mean selective sulcal volumes ( @entity12432 ) differed between subjects with and without @entity2657 4.5 and 21.2  mL (P  <  0.001). When separated into quartiles, the odds of qualitative @entity2657 increases as @entity12432 decreases. Compared to the highest @entity12432 quartile, smaller @entity12432 was associated with worse clinical outcomes. CONCLUSION: @entity2657 can be quantified using volumetric analysis of @entity12432 measurements on routine CT scans. Smaller @entity12432 on admission is predictive of worse clinical outcomes. @entity12432 may be an important marker of EBI after @entity510 .
