Temporal changes in the prevalence and associates of foot ulceration in type 2 XXXX : The Fremantle @entity6 Study.

@entity1 @entity1095 @entity6 @entity1066 @entity1897 @entity613
AIMS: To assess temporal changes in foot ulceration and its risk factors in community-based @entity1 with type 2 @entity6 . METHODS: Baseline data from the longitudinal observational Fremantle @entity6 Study collected from 1993 to 1996 (Phase I) and 2008 to 2011 (Phase II) were analyzed. Generalized linear modeling was used to examine changes in foot @entity1066 prevalence and its associates between phases. Multiple logistic regression was used to determine associates of prevalent foot ulceration in individual and pooled phases. RESULTS: There were 16 foot @entity1066 among 1296 @entity1 in Phase I (1.2%) and 23 in 1509 Phase II @entity1 (1.5%; P=0.86 after age, sex and race/ethnicity adjustment). Glycemic and non-glycemic cardiovascular risk factors were better in Phase II, but @entity6 duration was longer, @entity1897 ( @entity1897 ) was more prevalent and more @entity1 were Aboriginal (P<0.001) than in Phase I. In multivariable analysis of both phases and pooled data, @entity6 duration and @entity1897 ( @entity1897 ) were independent associates of foot ulceration (P <=0.026). Prior hospitalization for @entity1066 , @entity613 , any absent pedal pulse and Aboriginality were also significant in the pooled model (P <=0.009). CONCLUSIONS: Strong associations between foot @entity1066 and @entity6 duration, @entity1897 , symptomatic and clinically-detectable @entity1095 were observed. Aboriginality also proved an independent risk factor. Since all these risk factors apart from @entity613 and impalpable foot pulses were more prevalent in Phase II, improved community- and hospital-based foot care between phases are likely to have attenuated the risk of foot @entity1066 in Phase II @entity1 .
