Significance of incidental desmoids identified during surgery for XXXX .

@entity1 @entity765 @entity1412
PURPOSE: The behavior of intra-abdominal desmoids in @entity1412 is incompletely understood. Findings range from typical mass lesions to flat sheets, termed the desmoid reaction or desmoid precursor lesion. The latter often are incidental findings of uncertain significance. The study was designed to describe the natural history of @entity765 with particular reference to the desmoid reaction. METHODS: @entity1 who underwent laparotomy for @entity1412 at the Cleveland Clinic Foundation were identified. The incidence of @entity765 was determined by review of operative records. @entity765 were classified as mass lesions if three-dimensional or desmoid reaction if two-dimensional. The incidence of clinically apparent @entity765 (typical mass lesions on physical examination or cross-sectional imaging in symptomatic @entity1 ) was determined by chart review. The incidence of clinical @entity765 between groups was compared by Fisher's exact test. RESULTS: A total of 266 @entity1 (153 females; median age, 26 (range, 9-63) years) underwent abdominal surgery for @entity1412 . @entity765 were identified in 34 @entity1 : 8 at the index surgery and 26 at relaparotomy. These lesions influenced the planned procedure in eight cases (26 percent), including preventing ileoanal pouch in 3 of 19 @entity1 in whom this was intended. The median follow-up from the time of identification of intra-abdominal desmoids was 42 (range, 2-178) months at which point four @entity1 (11 percent) had developed clinical @entity765 . There was no significant difference in incidence of clinical @entity765 between mass and desmoid reaction groups ( P = 0.27). CONCLUSIONS: @entity765 are a common finding at relaparotomy in @entity1 with @entity1412 . These lesions influence planned surgery in a minority of cases. Desmoid reaction may have little bearing on the subsequent development of clinically significant @entity765 .
