Is Myopic Optic Disc Appearance a Risk Factor for Rapid Progression in Medically Treated XXXX With Confirmed Visual Field Progression?

@entity1 @entity227 @entity1538 @entity2516 @entity726 @entity735
PURPOSE: To investigate @entity227 ( @entity227 ) progression rates in @entity735 with myopic optic disc appearance, @entity2516 , and progressive @entity227 changes and to compare the rates with those of a nonmyopic group. @entity1 AND METHODS: Data on 158 eyes from 131 @entity1 with @entity1538 who had progressive @entity227 deterioration during follow-up were retrospectively analyzed. The myopic and nonmyopic groups were compared in terms of rates of change of mean thresholds in global and regional areas using central 10 degrees, peripheral 10 to 24 degrees, and @entity726 hemifield test maps by using a linear-mixed model and controlling for confounding covariates. Clinical factors associated with rapid @entity227 progression at global and regional @entity227 areas were investigated in each group. RESULTS: The 2 groups did not significantly differ in the mean global @entity227 progression rate (-0.36 vs. -0.35 dB/y, respectively; P=0.951). Likewise, both groups showed similar @entity227 progression rates at all regional clusters (P>0.05). No significant association was found between the rate of @entity227 change and clinical factors in the myopic group. The mean follow-up intraocular pressure was significantly associated with @entity227 progression rates in the nonmyopic group (P<0.05). CONCLUSIONS: @entity1538 eyes with myopic optic disc appearance experiencing progressive @entity227 changes showed similar @entity227 progression rates globally and regionally when compared with nonmyopic eyes after controlling for clinical factors related to @entity227 progression. None of the clinical factors in the myopic group were significantly associated with @entity227 progression rate, whereas the mean follow-up intraocular pressure was in the nonmyopic group.
