Allergen Specific IgE, Number and Timing of Past Suicide Attempts, and Instability in @entity1 with Recurrent XXXX .

@entity1 @entity1032 @entity308 @entity162 @entity566 @entity1316 @entity56
Suicide and decompensation of @entity1032 peak in spring and, to a lesser extent, in fall. Several recent studies reported that suicide and decompensation peaks coincided with spring and fall aeroallergen peaks. @entity56 occur as the result of a complex biochemical cascade initiated by IgE antibodies (sensitization) and allergens (triggers). Animal models have shown molecular/neurochemical changes in the brain, as well as relevant behavioral changes associated with this IgE-mediated biochemical cascade. These factors suggest that @entity566 could precipitate suicidality and mood instability. In the current study, we compared the prior suicide attempt and history of decompensation of @entity1316 in allergen sensitive vs nonsensitive @entity1 . Further, we compared the ratio of events (attempts and decompensations) during the @entity566 season to events occurring during the rest of the year. @entity1 with @entity308 or @entity162 (n=80) were studied. There were no statistical differences in any measurement performed between the allergen sensitive and nonsensitive @entity1 . These negative results are not consistent with recent epidemiological studies supporting a predictive association between @entity566 and categorical measures of suicidality (ideation, attempts, and completion). Clinical samples are likely not adequate to study less than strong predictive associations with suicide and suicide risk factors.
