XXXX incidence patterns by ICCC-3 subtype in Mexico City metropolitan area population insured by Instituto Mexicano del Seguro Social, 1996-2010.

@entity1 @entity1987 @entity706 @entity5 @entity2109 @entity4383 @entity1893 @entity978
PURPOSE: We reviewed the @entity706 epidemiological data for the Mexico City metropolitan area (MCMA). METHODS: Data analysis from @entity1 (0-14  years old) diagnosed with @entity706 during the period 1996-2010 was performed at the Mexican @entity5 Registry. Histological subtype was determined according to the International Classification of @entity5 3 (ICCC-3). Age-adjusted incidence rates were calculated per 1,000,000 @entity1 /year by age, gender, and ICCC-3 subtype; trends, by @entity1987 ( @entity1987 ). RESULTS: A total of 328 @entity706 cases included in the study had an incidence rate of 11.8, showing a decreasing trend [ @entity1987 : -3.5; CI95% (-5.9, -1.0)], primarily due to @entity1893 ( @entity1893 ) and @entity978 ( @entity978 ) mixed cellularity subtype. @entity1893 had the major incidence (5.8), with the precursor cell subtype being the most frequent (38.3  %). @entity4383 was the most frequent @entity978 subtype. The incidence of @entity2109 was low (1.3). During the study period, there was an important reduction in the not-otherwise-specified @entity1893 , which translated into a relative increase in the IIb3 subtype [ @entity1987 : 7.3 (1.2, 13.8)]. Low incidences of @entity1893 and of @entity978 and @entity1893 were found for <1-year-olds and for 10- to 14-year-olds, respectively. Incidence rates for @entity1 in the MCMA, particularly the <1 and 10-14 age groups, were lower than those for developed countries. The overall male/female ratio was 2.3. CONCLUSIONS: There was a trend toward a reduced incidence, for some @entity706 subtypes, in particular for @entity706 , which may be the result of improvement in diagnostic techniques.
