Acute XXXX in Johannesburg. Ethnic differences in incidence, cell type, and survival.

@entity1 @entity3329 @entity981 @entity149 @entity3052 @entity1334 @entity1778 @entity3203
Acute @entity1778 was found to be less common in black @entity1 than in white @entity1 in the Johannesburg area of South Africa. Of 195 consecutive @entity1 , 78 were black and 117 white. The annual incidence was 0.8/100,000 black @entity1 and 3.3/100,000 white. The low incidence in black @entity1 was due to the very low incidence of @entity981 ( @entity981 ), which was 0.41/100,000 black @entity1 compared with 2.73/100,000 white @entity1 . The incidence of @entity3052 ( @entity3052 ) was approximately the same for both ethnic groups; 0.38/100,000 black @entity1 and 0.57/100,000 white @entity1 . Remission rates for black @entity1 with @entity981 were lower than for white @entity1 and the cumulative proportion of black @entity1 surviving at 60 months was only 32% compared with 72% of white @entity1 (p = 0.0001). The most significant poor prognostic factors in @entity981 were ethnic group and age (p = 0.0006), @entity149 at onset (p = 0.006), @entity1334 L2 and L3 morphology (p = 0.05), and irregular clinic attendance during maintenance therapy (p = 0.05). In @entity3052 , remission and survival rates were less favorable than in @entity981 but there were no significant differences between black and white @entity1 . Black @entity1 exhibited certain clinical features rarely seen in white @entity1 , including chloromata, oropharyngeal lesions, and CNS involvement at onset. @entity3203 were common. The most significant poor prognostic factors in @entity3052 were @entity149 at onset (p = 0.03), generalized @entity3329 (p = 0.0001), and @entity1334 morphology classification M3-M6 (p = 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
