Evaluation of opium effect on pancreatobiliary system in opium addicted XXXX by endoscopic ultrasonography.

@entity1 @entity788 @entity66 @entity5 @entity15149 @entity854
INTRODUCTION: @entity854 in @entity1 with opium addiction have not been widely evaluated by endoscopic ultrasonography before. MATERIALS AND METHODS: @entity1 without any @entity66 during 10 months were enrolled in this study. Common bile duct (CBD), @entity788 ( @entity788 ) and portal vein (PV) diameters, gallbladder wall thickness and surface area of the @entity854 were evaluated in both groups by endosonography. RESULTS: In total, 199 @entity1 were evaluated. 36 (18.1%) cases were addicted to opium. Mean age of the @entity1 was 56.0    14.2 years. Opium users had a statistically significant higher (all P < 0.001) mean diameters of distal CBD (4.6    1.9 vs. 3.1    1.0 mm), middle part of CBD (7.5    3.1 vs. 4.6    1.6 mm), @entity788 in head (3.3    1.3 vs. 2.3    0.7 mm) and PV (10.3    2.3 vs. 8.9    2.1 mm). However, the difference in the diameters of @entity788 in the body of pancreas and gallbladder wall thickness did not reach statistical significance. The size of the papilla as measured by the surface area of the papilla of Vater was also significantly larger in opium users (40.6    17.1 vs. 29.9    13.5, P < 0.001). CONCLUSION: Opium addicted @entity1 have larger diameters of CBD, PV and a larger surface area of the papilla of Vater. Dilated @entity788 only in the head of the pancreas might be an important clue to differentiate @entity15149 -induced CBD dilation from @entity5 and chronic @entity788 . The clinical significance of these findings warrants further investigation.
