Do @entity409 and freezing of gait in XXXX share the same neuroanatomical correlates?

@entity1 @entity409 @entity191 @entity1334 @entity194 @entity179 @entity6556
UNASSIGNED: Current hypotheses postulate a relationship between @entity409 and freezing of gait ( @entity6556 ) in @entity191 ( @entity191 ). Hitherto, most evidence comes from entirely clinical approaches, while knowledge about this relationship on the morphological level is sparse. The aim of this study was therefore to assess the overlap of gray matter @entity194 associated with @entity6556 and @entity409 in @entity191 . We included 18 @entity191 @entity1 with @entity6556 and 20 without @entity6556 in our analysis. A voxel-based morphometry approach was used to reveal voxel clusters in the gray matter which were associated with @entity6556 and @entity409 as measured by the Frontal Assessment Battery, respectively. Conjunction analysis was applied to detect overlaps of the associated patterns. @entity6556 correlated with different cortical clusters in the frontal and parietal lobes, whereas those associated with the @entity1334 scores were, although widespread, widely confined to the frontal lobe. Conjunction analysis revealed a significant cluster of gray matter loss in the right dorsolateral prefrontal cortex. We could show that the patterns of @entity179 associated with @entity6556 and @entity409 (as measured by the @entity1334 ) share atrophic changes in the same cortical areas. However, there is also a considerable number of cortical areas where neurodegenerative changes are only unique for either sign. Particularly, the involvement of parietal lobe areas seems to be more specific for @entity6556 .
