XXXX in the extremity: case report and review of the literature.

@entity1 @entity588 @entity5 @entity7944 @entity3 @entity2280 @entity2460
A @entity2460 is a relatively unusual @entity5 first described as a distinctive @entity5 arising from pleura. Some reports have shown that @entity2460 also affect extrathoracic regions. The current study presents a literature review with four additional @entity1 with @entity2460 arising from the extremities to clarify clinicopathologic features. The current four @entity1 were two males and two females, ranging from 17 to 60 years of age. Magnetic resonance imaging scans of the current @entity1 showed inhomogeneous low to intermediate intensity signal on T1-weighted images and inhomogeneous intermediate to high intensity signal on T2-weighted images. Histologically, the @entity5 were composed of a haphazard proliferation of spindle cells, although cellularity was variable in each case. Two of the four @entity5 showed hypercellularity of spindle cells with focally myxomatous or hyaline changes, whereas @entity7944 with scattered spindle cells throughout the specimens were observed in the other two @entity5 . Immunohistochemically, all four @entity1 showed positive immunoreactivity for @entity2280 , and two @entity5 showed focally positive immunoreactivity for @entity588 protein. During the followup of 12 to 54 months, neither local recurrence nor distant @entity3 was detected after wide resection. Examination of the literature and the current @entity1 suggests that @entity2460 in the extremities are likely to have a malignant potential, although most @entity1 have a benign clinical course. Local wide resection and careful long-term followup are necessary for @entity1 with @entity2460 in the extremities.
