[Transurethral microwave-thermotherapy in the treatment of XXXX ].

@entity1 @entity1067 @entity1486 @entity39
OBJECTIVE: Determining the therapeutic efficacy of transurethral microwave thermotherapy (TUMT) in @entity1067 ( @entity1067 ). DESIGN: Prospective. SETTING: Department of Urology, University Hospital Nijmegen, the Netherlands. METHOD: In the outpatient clinic, 130 @entity1067 @entity1 (mean age: 65.9 years (SD: 6.9); mean prostatic volume 50.2 cm3 (SD: 18.4)) received TUMT in a single session lasting 60 min. The prostate was heated to above 45 degrees C by a microwave antenna in a urethral catheter, resulting in tissue @entity39 . In the first year after treatment the Madsen symptom score, maximal flow, residual volume, prostatic volume and concentration of @entity1486 in blood were collected. RESULTS: After 1 year 98 @entity1 could be evaluated; of the other 32, 16 withdrew from follow-up, 10 underwent transurethral prostate resection and 6, other treatment. The maximal flow increased by 1.2 ml/s (SD: 4.0). The residual volume decreased by 15.8 ml (SD: 55.6). Symptom scores improved by 5.9 points (SD: 5.0). A 50% increase in symptom score was seen in 49.5% of all @entity1 ; 24.3% showed no improvement of complaints. There was no change in prostatic volume, whereas PSA concentration showed a transient increase in the first week after TUMT. Preliminary results after 6 months' follow-up of a randomised placebo-controlled study in 50 @entity1 showed subjective and objective improvement of miction. CONCLUSION: TUMT results in distinct subjective improvement. Urodynamic findings show a less pronounced improvement.
