XXXX . A clinical, histologic, and immunologic study of five cases.

@entity1 @entity1712 @entity1619 @entity353 @entity706 @entity1661 @entity3191 @entity1395 @entity1600 @entity1072 @entity1897 @entity381 @entity382 @entity236
The authors describe five white @entity1 with @entity3191 . Four @entity1 were older than 65 years. All cases presented with a short clinical course and advanced stage at the time of diagnosis. Clinical manifestations included @entity1395 , @entity353 , peripheral and @entity1661 . One case showed tonsillar involvement and subcutaneous @entity1600 ; @entity382 was present in four cases, two of them with @entity381 . Only one case presented @entity1897 and antibodies to @entity1 @entity1619 . Although three cases were classified as diffuse @entity706 and two as poorly differentiated @entity1072 , there were some common characteristics: diffuse infiltration by different proportions of small lymphoid cells and large immunoblasts, some of them multinucleated and similar to Reed-Sternberg cells; accumulation of histiocytes, plasmacytosis, @entity1712 , venular proliferation and compartmentalization were also found. @entity236 was observed in two @entity1 . Results of monoclonal markers showed four cases to be OKT4+ and the other OKT8+. The morphologic and immunologic characteristics of these @entity1 were typical and similar to those reported from other geographical areas.
