[Change of ambulatory blood pressure-related parameters for different levels of renal function in resistant XXXX ].

@entity1 @entity8 @entity101 @entity13519
OBJECTIVE: To explore the predictive values of ambulatory blood pressure-related parameters for moderate @entity8 in resistant @entity101 (RH). METHODS: The clinical data were retrospectively analyzed for 401 hospitalized @entity1 with @entity101 at our hospital from October 2010 to October 2013. They were divided into RH (n = 263) and non-RH (n = 138). The modified estimating equation of glomerular filtration rate (GFR) for Chinese @entity1 was used to assess renal functions. The standardization of moderate @entity8 was when GFR below 60 ml    min(-1)    1.73 m(-2). The ambulatory blood pressure-related parameters were obtained by 24 h ambulatory blood pressure monitoring. The important prediction of these parameters for moderate @entity8 was accessed by receiver operating characteristic (ROC) curve. And the related risk factors for @entity8 were tested by multiple stepwise Logistic regression analysis. RESULTS: Ambulatory arterial stiffness index (AASI), 24 h mean pulse pressure (24 hPP), sleeptime relative systolic blood pressure ( @entity13519 ) decline and 24 h systolic blood pressure (24 @entity13519 ) had important predictive values for moderate @entity8 in RH. GFR was significantly lower in those with AASI >=  0.485, 24 hPP >=  47.5 mmHg, sleeptime relative @entity13519 decline  <= -1.75% and 24 @entity13519 >=  130.5 mmHg (P < 0.05). Area under curve of ROC curve of AASI, 24 hPP, sleeptime relative @entity13519 decline and 24 @entity13519 were 0.804, 0.644, 0.602 and 0.623 respectively. Multiple Logistic regression analysis showed that AASI (OR 1 268.5, P = 0.000), low density lipoprotein (OR 0.7, P = 0.01) and sleeptime relative @entity13519 decline (OR 1.3, P = 0.01) were independent risk factors for GFR < 60 ml    min(-1)    1.73 m(-2) in RH. CONCLUSION: AASI, 24 hPP, sleeptime relative @entity13519 decline and 24 @entity13519 are the most significant ambulatory blood pressure-related parameters in predicting @entity8 in resistant @entity101 .
