Serum Gamma-Glutamyltransferase and Ferritin are Related to XXXX Resistance: A Population-Based Study.

@entity1 @entity23109 @entity10745 @entity5906 @entity2690 @entity53139 @entity3929 @entity412 @entity1011 @entity209 @entity413 @entity165 @entity414
BACKGROUND: Recent studies have reported the association of gamma-glutamyltransferase ( @entity53139 ) or ferritin with @entity209 . However, there has been no large population-based study assessing the interrelationship of these two biomarkers and their association with @entity2690 resistance. METHODS: A population-based cross-sectional study was carried out in the Chinese Liangshan Yi ethnic group. 756 eligible subjects, aged 20 - 74 years, were included. Demographic characteristics, medical history, and lifestyle data were collected through questionnaires. An oral @entity413 tolerance test was performed. Laboratory tests, including @entity53139 and ferritin measurements, were conducted. Spearman's rank-order correlation and multiple linear regression were used to calculate the correlation of @entity53139 with ferritin and their relationship to the @entity2690 resistance index determined by the homeostasis model assessment (HOMA-IR). RESULTS: A significant correlation between serum @entity53139 and ferritin levels was found (r = 0.393, p < 0.05). @entity53139 was independently correlated with ferritin after adjustment for age, gender, place of residence, education, income, leisure-time physical activity, drinking, smoking, body mass index, systolic pressure, diastolic pressure, @entity23109 , @entity10745 , @entity5906 aminotransferase, @entity3929 aminotransferase, total @entity165 , low density lipoprotein- @entity165 , @entity412 , high density lipoprotein- @entity165 , fasting plasma @entity413 , 2-hour postprandial plasma @entity413 , @entity414 , and urinary albumin to @entity1011 ratio (p < 0.05). Positive correlations were established between @entity53139 (standard b = 0.252) or ferritin (standard b = 0.181) after adjustment for multiple confounders (p < 0.05). CONCLUSIONS: @entity2690 resistance is associated with elevated serum @entity53139 and ferritin. A combined determination of @entity53139 and ferritin might lead to better predictions in @entity1 with @entity2690 resistance.
