High dose-rate intracavitary brachytherapy for XXXX occurring after hysterectomy: a rational prescription of radiation dose.

@entity1 @entity548 @entity5 @entity8376 @entity811 @entity3137
OBJECTIVE: Our purpose was to profile @entity1 who were treated with high dose-rate intracavitary brachytherapy for @entity8376 that occurred after hysterectomy, with special reference to a rational prescription of radiation dose. STUDY DESIGN: We reviewed 13 @entity1 who were treated for posthysterectomy @entity8376 by the brachytherapy as the sole treatment. The brachytherapy was delivered by a remote-controlled afterloading intracavitary radiation system. RESULTS: The mean age of the @entity1 was 62 years. The total dose of absorbed radiation was 36 and 30 Gy that was prescribed at 1.0-cm depth to the vaginal surface in 3 cases and at 40 and 30 Gy that was prescribed at 0.5-cm depth in 10 cases. All @entity1 had @entity3137 changes of mild to moderate grade. Three cases that were irradiated to a total dose of 30 Gy at 1.0-cm depth had @entity548 and/or macroscopic @entity811 . Complaints regarding sexual functioning were not found in this retrospective analysis. All @entity1 remain free of disease after a median follow-up period of 127 months. CONCLUSION: High dose-rate brachytherapy with a dose prescription at 0.5-cm depth can yield a promising rate of @entity5 control, with lower associated morbidity than that with a dose prescription at 1.0-cm depth in the treatment of posthysterectomy @entity8376 .
