Does XXXX nasal douching help prevent polyp recurrence following functional endoscopic sinus surgery?

@entity1 @entity2379 @entity566 @entity1412 @entity11793
BACKGROUND: Recurrence of @entity1412 following surgical intervention is very common. Antifungal therapy has been an appealing alternative to reduce its recurrence and severity. Early studies showed definite positive response, but recent studies have raised doubts about its efficacy in treatment of @entity1412 . METHODS: This prospective case-control clinical trial was conducted on 50 @entity1 suffering from @entity1412 in Isfahan University of medical sciences. All @entity1 underwent functional endoscopic sinus surgery. CT scanning of paranasal sinuses was done preoperatively and 6 months postoperatively to stage the disease. @entity1 were assigned to two groups: @entity11793 group were instructed to irrigate the nasal cavity with a solution of @entity11793 , while the normal saline group used the physiologic normal saline for 6 months. RESULTS: 68% of @entity1 in Normal saline and 84% of cases in @entity11793 group reported history of @entity566 . In @entity11793 group, stage of the disease improved in 84% of @entity1 and remained unchanged in the rest. In normal saline group, imaging stage improved in 22 @entity1 and remained unchanged in 3. The two cohorts were compared for reduction in imaging stage and no significant difference was found between them. CONCLUSIONS: This study showed no benefits for topical @entity2379 solution over normal saline. It might be better to retreat to the traditional normal saline nasal douching following functional endoscopic sinus surgery in the treatment of @entity1412 .
