Does Nasal Surgery Improve OSA in XXXX with Nasal Obstruction and OSA? A Meta-analysis.

@entity1 @entity27
OBJECTIVE: To perform a systematic review and meta-analysis to determine if isolated nasal surgery in @entity1 with @entity27 and nasal airway obstruction @entity27 . DATA SOURCES: Computerized searches were performed in PubMed, EMBASE, and the Cochrane Library through October 2014. Manual searches and subject matter expert input was also solicited. REVIEW METHODS: A search protocol was defined a priori, and 2 independent investigators performed the data extraction, focusing on relevant data, including quality data polysomnography data, and taking note of methodological quality and risk for bias. RESULTS: The 10 studies meeting criteria included a total of 320 @entity1 . There were 2 randomized controlled trials, 7 prospective studies, and 1 retrospective study. There was a significant improvement in the pooled results of both Epworth Sleepiness Scale (ESS; difference 3.53, 95% confidence interval [CI] [0.64, 6.23]) and Respiratory Disturbance Index (RDI; 11.06, 95% CI [5.92, 16.19]) scores with isolated nasal surgery. There was no significant improvement in the @entity27 ( @entity27 ) in the random effects model (4.83, 95% CI [-1.6, 11.62]). CONCLUSIONS: The pooled results showed that isolated nasal surgery for @entity1 with @entity27 improved some sleep parameters, as shown by significant improvements in ESS and RDI, but had no significant improvements on @entity27 . Future controlled studies with larger groups are needed to confirm the benefits of isolated nasal surgery in this @entity1 population.
