Sex Differences in Acute @entity301 in a Multiethnic Asian Population: Results of the Malaysian National @entity65 Database-Acute XXXX (NCVD- @entity1187 ) Registry.

@entity1 @entity1187 @entity712 @entity101 @entity6 @entity301 @entity117 @entity1459 @entity583 @entity65
BACKGROUND: Sex differences in @entity1187 ( @entity1187 ) have been well studied in major registries and clinical trials in Western populations. Limited studies have examined the sex differences in @entity1187 using a large number of Asian @entity1 as the subjects. OBJECTIVES: The aim was to study the sex differences in @entity1187 using the NCVD- @entity1187 (National @entity65 Database-Acute @entity301 ) registry. METHODS: We analyzed 13,591 @entity1187 @entity1 , of which 75.8% were @entity1 and 24.2% were @entity1 , from March 2006 to February 2010. Data were collected on demographic characteristics, risk factors, anthropometrics, treatments, procedures, mortalities, and complications. The results were compared among 3 cohorts of @entity1187 (ST-segment elevation @entity583 [STEMI], @entity583 , and @entity1459 ). RESULTS: @entity1 were older and more likely to have @entity6 , @entity101 , previous @entity712 , and cerebral vascular accidents than @entity1 were. @entity1 were less likely to receive in-hospital administration of @entity117 , beta-blockers, angiotensin-converting enzyme inhibitors, or angiotensin receptor blockers, and they were less likely to undergo angiography and percutaneous coronary intervention. In STEMI, a significantly lower proportion of @entity1 than @entity1 received primary percutaneous coronary intervention (6.2% vs. 6.7%, respectively, p  = 0.000) and fibrinolysis (64.4% vs. 74.6%, respectively, p  = 0.000). In addition, with regard to STEMI, @entity1 had a significantly higher unadjusted in-hospital mortality rate than @entity1 did (15.0% vs. 8.1%, respectively, p < 0.000). There was no statistically significant in-hospital mortality difference between sexes for @entity583 and @entity1459 . After adjustment for age and other covariates, a multivariate analysis showed no sex differences in the in-hospital mortality in all spectrums of @entity1187 . CONCLUSIONS: Our study showed significant sex differences in the demographic characteristics, risk factors, treatments, and outcomes of @entity1187 . More importantly, in @entity1187 @entity1 , we found evidence of suboptimal treatments and interventions in @entity1 versus @entity1 . Our findings provide an opportunity to narrow the sex gap in the care of @entity1 with @entity1187 in Malaysia.
