Surgical outcome and prognostic factors of spinal XXXX in adults.

@entity1 @entity424 @entity5 @entity602 @entity51 @entity954
The goal of treatment for @entity424 is complete removal with minimal postoperative @entity51 . The authors correlated the results of surgical management for @entity602 with the rate of postoperative disease progression and the prognostic factors. Thirty-one cases of @entity424 , surgically treated between 1979 and 1998, were retrospectively analyzed. The authors reviewed clinical features, radiological characteristics and operative findings for the surgical outcome analysis. Thirty-five percent of @entity1 with preoperative Nurick's grade better than grade 4 showed improvement in functional status, whereas no improvement was observed in @entity1 with preoperatively poorer functional status (P = 0.05). The proportion of @entity954 was influenced by @entity5 location (40% in cases around the conus versus 97% in other regions, P = 0.003) and histology (42% in the myxopapillary subtype versus 97% in the non-myxopapillary subtype, P = 0.001). Disease progression was observed in six cases, the mean progression free interval after surgical removal was 83 months and the 5-year progression free rate was 70%. Disease progression was found in two out of 23 cases from the complete removal group and in four out of eight cases from the incomplete removal group (P = 0.008). In the aspect of disease progression, the only statistically significant factor by multivariate analysis was the surgical extent of removal (P = 0.010). Of those @entity1 where there was incomplete removal, radiation therapy lead to improved clinical results, which were not statistically significant (P = 0.27). In the surgical treatment of @entity602 , preoperative functional status and the extent of removal were the significant prognostic factors influencing postoperative outcome. Early diagnosis is @entity5 should be attempted in all surgical treatment of @entity424 .
