XXXX is significantly associated with somatisation in 840 @entity1 , which may drive bloating.

@entity1 @entity294 @entity344 @entity1142 @entity1744 @entity8352
BACKGROUND: Psychological factors may influence persistence and perceived severity of symptoms in @entity1744 ( @entity8352 ). Literature suggests that somatisation is associated with @entity8352 . However, the relationship between @entity8352 subtype, symptoms of @entity8352 and somatisation is unclear. AIM: To examine this issue in a large cohort of secondary care @entity1 . METHODS: Demographic and gastrointestinal (GI) symptom data were collected from 4224 adult @entity1 via the Rome III questionnaire. Somatisation data were collected using the @entity1 health questionnaire-12. Mean somatisation score and number of somatic symptoms were compared between @entity8352 @entity1 and controls with minimal @entity344 , and between @entity8352 subtypes using analysis of variance. Effect of level of somatisation on symptom frequency was compared according to @entity8352 subtype using a   (2) test. RESULTS: 840 @entity1 met Rome III criteria for @entity8352 , controls were 2137 @entity1 with @entity344 without @entity8352 . Mean somatisation scores and number of somatic symptoms were higher in @entity8352 vs. controls (P  <  0.001), and in mixed stool pattern @entity8352 ( @entity8352 ), vs. @entity8352 with @entity1142 ( @entity8352 -C) or @entity294 ( @entity8352 -D) (P  <  0.001). High levels of somatisation were more prevalent in @entity8352 (31.7%) vs. @entity8352 -C (22.5%) or @entity8352 -D (20.8%) (P  =  0.003). For all @entity8352 subtypes, high levels of somatisation were associated with a greater frequency of bloating or abdominal distension prior to logistic regression. CONCLUSIONS: @entity8352 is strongly associated with higher levels of somatisation, particularly @entity8352 . Bloating may be associated with higher levels of somatisation, perhaps explaining why it can be difficult to treat.
