Overground robot assisted gait trainer for the treatment of drug-resistant freezing of gait in XXXX .

@entity1 @entity2653 @entity191 @entity854 @entity6556
UNASSIGNED: Freezing of Gait ( @entity6556 ) is a frequent and disabling feature of @entity191 ( @entity191 ). Gait rehabilitation assisted by electromechanical devices, such as training on treadmill associated with sensory cues or assisted by gait orthosis have been shown to improve @entity6556 . Overground robot assisted gait training (RGT) has been recently tested in @entity1 with @entity191 with improvement of several gait parameters. We here evaluated the effectiveness of RGT on @entity6556 severity and @entity854 in @entity191 @entity1 . Eighteen @entity1 with @entity6556 resistant to dopaminergic medications were treated with 15 sessions of RGT and underwent an extensive clinical evaluation before and after treatment. The main outcome measures were @entity6556 questionnaire (FOGQ) global score and specific tasks for gait assessment, namely 10meter walking test (10MWT), Timed Up and Go test (TUG) and 360   narrow turns (360 NT). Balance was also evaluated through Fear of Falling Efficacy Scale (FFES), assessing self perceived stability and @entity2653 ( @entity2653 ), for objective examination. After treatment, FOGQ score was significantly reduced (P=0.023). We also found a significant reduction of time needed to complete TUG, 10MWT, and 360 NT (P=0.009, 0.004 and 0.04, respectively). By contrast the number of steps and the number of freezing episodes recorded at each gait task did not change. FFES and @entity2653 scores also improved, with positive repercussions on performance on daily activity and quality of life. Our results indicate that RGT is a useful strategy for the treatment of drug refractory @entity6556 .
