Maturational topography of the visual evoked potential in fetal XXXX .

@entity1 @entity742 @entity1276 @entity548 @entity854 @entity989
The normal maturational course of the visual evoked potential (VEP) in @entity1 newborns and @entity1 is well documented. Unfortunately, there is a paucity of data about VEP maturation in the 'normal' preterm @entity1 . Since this population is at risk to develop @entity854 affecting the VEP ( @entity548 , @entity1276 , and @entity989 ), one must question whether such VEP data collected from this group is representative of normal maturation. To provide normative parametric developmental data we have been studying VEP development in fetal @entity742 . Six fetal @entity742 between 105 and 120 days gestational age were externalized and surgically instrumented with subcutaneous recording electrodes placed over the occipital and parietal regions. High-intensity light-emitting diodes (LEDs) externalized fiberoptic cables were secured adjacent to the orbit. from 108 to 141 days gestation, fetal VEPs were recorded in response to bright flash stimulation and the maturational topography was investigated. Over the occipital regions, the emergence of major positivities at P400 and P650 were observed beginning around 120 days gestation. Over the parietal area, the emergence of P200 and P500 components was observed by 128 days gestation. The latency-maturation functions revealed that the slope of the parietal function was steeper than the occipital counterpart, suggesting that the maturation of parietal neurons occurs at a faster rate than neuronal development in the occipital regions.
