Progressive constriction of the hyperautofluorescent ring in XXXX .

@entity1 @entity2270 @entity6391
PURPOSE: To evaluate the constriction of the hyperautofluorescent ring over time in @entity1 with @entity6391 ( @entity6391 ). DESIGN: Prospective study. METHODS: Fourteen eyes of 14 @entity6391 @entity1 with a hyperautofluorescent ring were studied. Ring constriction was evaluated by measurements of its external and internal boundaries along the vertical and horizontal axes at baseline and at 12-, 24-, 36-, and 48-month follow-ups. Repeat fundus autofluorescence was obtained at 12, 24, 36, and 48 months in 13, 7, 5, and 1 eyes respectively. Spectral-domain optical coherence tomography (SD-OCT) images were obtained on 8 eyes and the horizontal extent of the inner segment/outer segment (IS/OS) junction was measured. SD-OCT was repeated at 12 and 24 months in 6 and 4 eyes respectively. RESULTS: The external boundaries of the ring were identified along the horizontal @entity2270 in 12 eyes and along the vertical @entity2270 in 13. Internal boundaries were identified in 7 eyes. Constriction was demonstrated in all @entity1 except 1 who demonstrated minimal expansion of the internal boundary along the horizontal @entity2270 . SD-OCT measurements showed a decrease in the IS/OS junction length. CONCLUSION: Progressive constriction of the hyperautofluorescent ring and a concordant decrease in IS/OS junction length were observed over time.
