[Therapy options in the case of advanced therapy resistant Morbus XXXX ].

@entity1 @entity5953 @entity304 @entity16 @entity3826
In Germany about 300,000 to 400,000 @entity1 are suffering from Morbus @entity304 at present. It is one of the most common @entity16 both in Germany and in Europe as a whole. With the rising number of elderly @entity1 in our population, the number of @entity304 @entity1 will strongly increase as well in future. About 20% of these @entity1 are already in an advanced stage. This stage leaves its marks with motor and non-motor sequelae. With the minority of these @entity1 oral medication is ineffective. For these relatively rare cases an indication for an L-dopa-infusion therapy (duodopa pump), an @entity3826 pump therapy or a deep brain stimulation may exist. The indication for one of these 3 therapy forms is given by the neurological clinic in agreement with the @entity1 and is only given in case of failure of oral medication. @entity5953 therapy options are very expensive. In case of the deep brain stimulation, close cooperation between the neurologist and the neurosurgeon as well as with the @entity1 is necessary. Experts warn about a transplantation of stem cells because there are no clinical studies and only partial clinical improvement with severe side effects are known. The transplantation of stem cells for advanced Morbus @entity304 is not a medically necessary treatment at present.
