Late XXXX enhancement among survivors of @entity1164 .

@entity1 @entity1164 @entity296 @entity1165 @entity943 @entity2224 @entity1121 @entity370 @entity2287 @entity2401 @entity204
OBJECTIVES: The aim of this study was to describe the role of contrast-enhanced cardiac magnetic resonance (CMR) in the workup of @entity1 with @entity1164 ( @entity1164 ) and in the prediction of long-term outcomes. BACKGROUND: @entity296 is a key substrate for @entity1164 , and late @entity2287 enhancement (LGE) on a CMR study is a robust technique for imaging of @entity296 . METHODS: We performed a retrospective review of all survivors of @entity1164 who were referred for CMR studies and performed follow-up for the subsequent occurrence of an adverse event ( @entity204 and appropriate defibrillator therapy). RESULTS: After a workup that included a clinical history, electrocardiogram, echocardiography, and coronary angiogram, 137 @entity1 underwent CMR for workup of @entity1164 (66% male; mean age 56    11 years; left ventricular ejection  fraction 43    12%). The presenting @entity943 were @entity2224 (n  = 105 [77%]) and @entity1165 (n  = 32 [23%]). Overall, LGE was found in 98 @entity1 (71%), with an average extent of 9.9    5% of the left ventricular myocardium. CMR imaging provided a diagnosis or an arrhythmic substrate in 104 @entity1 (76%), including the presence of an infarct-pattern LGE in 60 @entity1 (44%), noninfarct LGE in 21 (15%), active @entity2401 in 14 (10%), @entity1121 in 3 (2%), @entity370 in 3, and arrhythmogenic @entity296 in 3. In a median follow-up of 29 months (range 18 to 43 months), there were 63 events. In a multivariable analysis, the strongest predictors of recurrent events were the presence of LGE (adjusted hazard ratio: 6.7; 95% CI: 2.38 to 18.85; p  < 0.001) and the extent of LGE (hazard ratio: 1.15; 95% CI: 1.11 to 1.19; p  < 0.001). CONCLUSIONS: Among @entity1 with @entity1164 , CMR with contrast identified LGE in 71% and provided a potential arrhythmic  substrate in 76%. In follow-up, both the presence and extent of LGE identified a group at markedly increased risk of future adverse events.
