Contact endoscopy as a novel technique in the detection and diagnosis of XXXX in the head and neck: a brief review.

@entity135 @entity3137 @entity1697
Background. There are a variety of described noninvasive optical detection techniques for evaluation of @entity135 . Contact endoscopy is a promising method of in vivo microscopic examination whereby a rigid telescope is placed on a previously dye-stained mucosa allowing evaluation of the superficial cell layers of the epithelium. This technique produces real-time, magnified images of cellular architecture of surface mucosa comparable to histology without the need for biopsy. In this review, we will briefly summarize the efficacy of CE in the detection of precancerous and @entity1697 and its potential as a novel technique in early diagnosis, monitoring, and preoperative assessment of @entity3137 of the head and neck. Methods. PUBMED, MEDLINE, and COCHRANE search revealed five prospective articles on contact endoscopy for the diagnosis of @entity3137 in the head and neck. Results. The literature search yielded five prospective studies examining contact endoscopy for the diagnosis of benign versus malignant @entity135 . These reported a sensitivity and specificity of 77-100%, specificity of 66-100% and an accuracy of 72-92%. Conclusion. Contact endoscopy is a promising optical technology that may be a useful adjunct in the evaluation and diagnosis of benign and malignant @entity135 . Future prospective randomized double-blind studies of this detection method are required.
