Differences in eucaryotic cell binding of XXXX .

@entity1 @entity6402 @entity796 @entity235 @entity74 @entity1577 @entity526
The lungs of @entity1577 ( @entity1577 ) @entity1 are frequently chronically colonized by @entity796 . Recently there has been an increase in colonization by another pathogen @entity6402 , which can cause a rapid decline in clinical condition or death of the @entity1 . The nature of the factor(s) which predispose @entity1577 @entity1 to colonization by one or both of these opportunistic pathogens is unknown. It has been suggested that the @entity74 in @entity1577 @entity1 results in an increase in the number of epithelial cell receptors available to @entity796 in the lung, thus rendering @entity1577 @entity1 more susceptible to bacterial colonization than non- @entity1577 individuals. In this study, we have examined adherence of several strains of @entity796 and @entity6402 to a variety of continuous cell lines, as well as primary cultures of @entity1577 and non- @entity1577 nasal polyp cells. The results suggested that there may be a decrease in the number of receptors available to both strains of @entity796 on cells of @entity235 origin compared to @entity1 cells. Both strains appear to use pili as the primary adhesin, but there is also evidence that non-pilus adhesins contribute significantly to eucaryotic cell binding. @entity6402 exhibited microcolony formation on all cell types, which is typical of the localized adherence pattern characteristic of the enteropathogenic @entity526 . However, we were unable to demonstrate, with either @entity6402 or @entity796 , a significant increase in adherence to @entity1577 compared to non- @entity1577 nasal polyp cultures.(ABSTRACT TRUNCATED AT 250 WORDS)
