XXXX intestinal spirochetosis: right-side preference in the large intestine.

@entity1 @entity652 @entity344 @entity14
UNASSIGNED: @entity1 intestinal spirochetosis (HIS) is a @entity14 , and its clinicopathologic features remain unclear. The aim of this study was to examine its characteristics. We histologically reviewed paraffin-embedded section slides made in 2001, 2006, and 2011 at a single institution in Japan. Cases histologically exhibiting a distinct fringe formation were considered to have HIS. Information was obtained from pathology request forms. We identified 85 HIS cases among 4930 @entity1 (7 cases [0.5%) in 2001, 29 [1.7%] in 2006, and 49 [2.8%] in 2011]. Gastrointestinal symptoms were observed in 7.1% of HIS cases. @entity1 intestinal spirochetosis was more frequent in the right-side large intestine than in the left side. Among 224 samples from HIS cases, conventional (tubular, tubulovillous, and villous) @entity652 were found in 148 samples. These @entity652 were more frequent in the right side than in the left side, although neither their size nor morphology differed between the sides. Histopathologic evaluation suggested a year-upon-year increasing prevalence of HIS in Japan. A small number exhibited @entity344 . Both histologic sign of HIS and conventional @entity652 were more frequent in the right-side large intestine. Therefore, a right-side preference may be a characteristic of HIS.
