Low bone mass in @entity1 with XXXX : prevalence and risk factors in 59 Finnish @entity1 .

@entity1 @entity174 @entity170 @entity3814 @entity79 @entity460 @entity14257 @entity717 @entity5200 @entity560
AIM: @entity1 with motor disabilities are at increased risk of compromised bone health. This study evaluated prevalence and risk factors of low bone mass and @entity174 in these @entity1 . METHOD: This cross-sectional cohort study evaluated bone health in 59 @entity1 (38 males, 21 females; median age 10 y 11 mo) with @entity717 (Gross Motor Function Classification System levels II-V). Bone mineral density (BMD) in the lumbar spine was measured with dual-energy X-ray absorptiometry; BMD values were corrected for bone size (bone mineral apparent density [BMAD]) and skeletal maturity, and compared with normative data. Spinal radiographs were obtained to assess vertebral morphology. Blood biochemistry included @entity560 concentration and other parameters of @entity460 homeostasis. RESULTS: Ten @entity1 (17%) had sustained in total 14 peripheral @entity174 ; @entity174 predominated. @entity3814 were present in 25%. The median spinal BMAD z-score was -1.0 (range -5.0 to 2.0); it was -0.6 in those without @entity174 and -1.7 in those with @entity174 (p=0.004). @entity560 insufficiency was present in 59% of participants (serum @entity14257 <50 nmol/l) and @entity5200 in 27%. Low BMAD z-score and @entity5200 were independent predictors for @entity174 . INTERPRETATION: @entity1 with @entity717 are at high risk of @entity174 and @entity79 . Evaluation of bone health and prevention of @entity170 should be included in the follow-up.
