XXXX -32 intracavitary irradiation of @entity976 : current technique and long-term results.

@entity1 @entity227 @entity5 @entity73 @entity4614 @entity976 @entity3151 @entity2010
PURPOSE: The management of @entity1 with @entity976 is often multifaceted and multidisciplinary. The purpose of this study was to examine the results of @entity3151 -32 intracavitary irradiation in the treatment of @entity1 with predominately @entity976 . METHODS AND MATERIALS: Thirty @entity1 with @entity976 underwent @entity3151 -32 intracavitary irradiation at our center between 1981 and 1993. The median @entity1 age was 26 years (range, 3-70 years). Thirteen @entity1 had intracavitary irradiation as the primary surgery for their @entity5 , whereas 17 @entity1 had adjuvant intracavitary irradiation after microsurgical resection, fractionated radiotherapy, or both. @entity1 in the adjuvant treatment group were more likely to have preoperative anterior @entity4614 (p = 0.008 Fischer exact test) and @entity2010 (p = 0.003 Fischer exact test). The median follow-up was 37 months (mean, 46 months, range, 7-116 months). RESULTS: @entity3151 -32 intracavitary irradiation resulted in cyst regression in 28 of 32 treated cysts (88%). Ten @entity1 (33%) have had @entity5 progression requiring further surgical intervention. Three @entity1 (10%) died: two of @entity5 progression, and one of unrelated causes. Visual acuity and fields improved or remained stable in 63% of the @entity1 . Fifteen @entity1 had residual anterior pituitary function before intracavitary irradiation and 10 (67%) retained their preoperative endocrine status. New-onset @entity2010 occurred in 3 of 17 @entity1 (18%) who had normal posterior pituitary function preoperatively. Fourteen of 20 adult @entity1 (70%) continued to perform at their preoperative functional level; 3 of 5 pediatric @entity1 who were age appropriate at the time of treatment continued to develop normally. No difference was noted between primary and adjuvant treatment @entity1 with respect to cyst control, @entity227 , or endocrine preservation after @entity3151 -32 intracavitary irradiation. CONCLUSION: The goals of @entity976 management should be @entity5 control with preservation of @entity73 . @entity3151 -32 intracavitary irradiation is an important option that enhances the likelihood of achieving these goals in @entity1 with primarily @entity976 .
