Transcranial magnetic stimulation in Doberman Pinschers with clinically relevant and clinically irrelevant XXXX on magnetic resonance imaging.

@entity1797 @entity1745 @entity235
OBJECTIVE: To evaluate the use of transcranial magnetic stimulation for differentiating between clinically relevant and clinically irrelevant cervical @entity1745 on magnetic resonance imaging (MRI). DESIGN: Validation study. ANIMALS: Clinically normal Doberman Pinschers without (n = 11) and with (6) @entity1745 on MRI and 16 Doberman Pinschers with @entity1797 ( @entity1797 ). PROCEDURES: After @entity235 were sedated, transcranial magnetic motor evoked potentials were recorded from the extensor carpi radialis muscle (ECRM) and cranial tibial muscle (CTM). Onset latencies and peak-to-peak amplitudes were measured. Magnetic resonance imaging was performed to identify @entity1745 . RESULTS: There were significant differences in ECRM and CTM onset latencies between Doberman Pinschers with @entity1797 and each of the 2 groups of clinically normal @entity235 , but there were no significant differences in ECRM and CTM onset latencies between the 2 groups of clinically normal @entity235 . There were significant differences in CTM peak-to-peak amplitudes between Doberman Pinschers with @entity1797 and each of the 2 groups of clinically normal @entity235 , but there were no significant differences in ECRM peak-to-peak amplitudes among groups or in CTM peak-to-peak amplitudes between the 2 groups of clinically normal @entity235 . There was a significant correlation between severity of @entity1745 and ECRM onset latency, CTM onset latency, and CTM peak-to-peak amplitude. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that transcranial magnetic stimulation may be a useful diagnostic tool to differentiate between clinically relevant and clinically irrelevant @entity1745 identified on MRI alone.
