Impact of exercise-induced XXXX on @entity1121 outcomes.

@entity1164 @entity1 @entity339 @entity3585 @entity1184 @entity1283 @entity1167 @entity340 @entity1121
AIMS: Rest echocardiography plays a role in @entity1121 ( @entity1121 ) diagnosis and risk stratification because left @entity1283 , severe left ventricle (LV) @entity1184 , and rest @entity3585 ( @entity3585 ) gradients >= 50 mmHg are @entity1164 risk factors that have been highlighted in recent guidelines. Conversely, the lack of evidence makes that exercise-echocardiography findings play a limited role. In clinical practice, @entity3585 gradient, but also @entity339 ( @entity339 ) or pulmonary pressure, seems relevant parameters to look for, during the exercise. Therefore, we sought to determine whether exercise-induced changes in myocardial and valvular functions could improve @entity1121 risk stratification. METHODS AND RESULTS: Consecutive primitive @entity1121 @entity1 with a preserved LV ejection fraction underwent standardized exercise echocardiography (including the assessment of myocardial function, dynamic left intraventricular gradient, and @entity340 ) at baseline and were clinically followed for a median of 29.3 months. The primary endpoint was a composite criterion that included death from any cause, @entity1167 , and hospitalization for a cardiovascular event. A total of 126 @entity1 were included. Eighteen @entity1 reached the primary endpoint. According to univariate Cox regression analysis, exercise @entity3585 gradient >= 50 mmHg [hazard ratio (HR) = 3.31, P = 0.01] and significant (>= 2/4) exercise @entity339 (HR = 3.64, P < 0.01) were associated with the primary endpoint. @entity1 with significant @entity339 had significantly higher rest and exercise @entity3585 gradients (P = 0.001 and P = 0.001) and larger left atria volumes (P < 0.001). CONCLUSION: Significant exercise-induced @entity339 appears to significantly impact the prognoses of @entity1121 @entity1 , and it is also associated with higher @entity3585 rest and exercise gradients.
