Haemodynamic and blood gas changes in buffaloes ( XXXX ) in the supine position following thiopentone anaesthesia with premedication.

@entity72215 @entity11520 @entity26 @entity338 @entity551 @entity19014 @entity22292
Studies were undertaken on seven adult female buffaloes ( @entity11520 ) premedicated with @entity72215 (0.3 mg/kg) and @entity22292 (30 mg/kg). Anaesthesia was induced with @entity19014 (10 mg/kg) and animals were kept under intermittent positive pressure ventilation. Measurements were made for 30 min in the lateral position, for 20 min in the supine position and subsequently for 40 min again in the lateral position. @entity338 during anaesthesia was avoided by evacuation of the rumen by rumenotomy two days prior to the experiment. When animals were in the lateral position there were minimal changes in arterial pressure and heart rate but central venous pressure rose. These changes were related to intermittent positive pressure ventilation. In the supine position, increase in heart rate (28%) was associated with profound @entity551 (56%) and decrease in central venous pressure (171%) in these animals. There was a fall in venous @entity26 tension and a marked increase (91%) in @entity26 extraction ratio. Restoration to the lateral position ameliorated all these changes rapidly. It was suggested that a 'low pressure-low flow' circulatory state exists in anaesthetised adult buffaloes in the supine position.
