Squash Cytology of a Dural-Based High-Grade Chondrosarcoma May Mimic That of XXXX in the Central Nervous System.

@entity1 @entity511 @entity263 @entity5 @entity189 @entity4483 @entity2277 @entity2414 @entity463 @entity3554 @entity4653
BACKGROUND: Intracranial @entity511 is rare, and most cases occur in the skull base. Intradural @entity511 is even rarer. CASE: Here, we describe a case of @entity511 with a radiation history for @entity189 and a radical prostatectomy for @entity263 15 and 8 years earlier, respectively. A 67-year-old @entity1 presented with a 3-week @entity2414 and @entity4653 . Computed tomography and magnetic resonance images of the brain revealed a dural-based mass in the left temporal area. Under the impression of a @entity463 , a resection and an intraoperative squash cytology were done. A necrotic dirty background as well as bluish-to-pinkish myxoid stroma were characteristic; the nuclei of highly @entity5 cells were hyperchromatic to vesicular with an occasional ground-glass appearance. The cytoplasm was of an eosinophilic hyalinized condensed morphology with an occasional granular appearance. Histologically, the lobulated mass was composed of hypercellular lobules of well-differentiated chondrocytes intermixed with anaplastic pleomorphic cells and diagnosed as a conventional grade III @entity511 . These cells were immunoreactive for D2-40, @entity4483 protein and @entity2277 . Brain invasion was also found. CONCLUSION: Albeit rare, dural-based @entity511 should be considered in the differential diagnosis for @entity3554 , especially in the case of previous radiation therapy.    2015 S. Karger AG, Basel.
