XXXX in @entity280 : another piece of the puzzle.

@entity1 @entity5 @entity1358 @entity280 @entity703
The association of @entity280 is well recognized. However, the most appropriate surgical approach in @entity1 with @entity280 and @entity703 remains controversial. We examine this controversy and report on our experience. Our cohort consisted of 28 affected members of three @entity280 kindreds. Screening of these individuals consisted of an abdominal ultrasound (US) in their early teens and a baseline computerized axial tomography (CT) scan in their late teens. To date, nine @entity1 have been found to have @entity1358 . In three of these @entity1 , the surgical specimen revealed multiple small foci of "clear cells" characteristic of @entity1358 that had not been detected by careful radiological assessment prior to surgery. In two @entity1 , these lesions were located at the opposite pole from the radiologically-detected @entity5 . Nephron-sparing surgery, therefore, risks leaving potential @entity5 that may be responsible for mortality. Conversely, radical procedures condemn a @entity1 to life-long dialysis and/or transplantation with associated risk and morbidity. The potential for the metachronous emergence of @entity1358 , however, justifies efforts to preserve normal tissue in @entity1 harboring radiologically-detected lesions; however, we need to know with some certainty the natural history of the correct management of this disorder.
