Risk of Obstructive Sleep Apnea in Adult XXXX with @entity565 : A Population-Based Cohort Study in Taiwan.

@entity1 @entity565 @entity27 @entity479
BACKGROUND: There are several publications reported that @entity27 ( @entity27 ) was associated with @entity565 . However, large-scaled, population-based cohort study has been limited. We aimed to examine the risk of @entity27 among adult @entity1 with @entity565 in an Asian population. METHODS: We conducted a retrospective cohort study using data from the National Health Insurance (NHI) of Taiwan. The @entity565 cohort included 38,840 newly diagnosed @entity1 between 2000 and 2010. The date of diagnosis was defined as the index date. Each @entity1 was randomly matched with four @entity1 without @entity565 according to gender, age, and the index year as the comparison cohort. The occurrence of @entity27 was followed up until the end of 2011. The risk of @entity27 was estimated using the Cox proportional hazard model after adjusting for gender, age, and comorbidities. RESULTS: The overall incidence of @entity27 was 2.51-fold greater in the @entity565 cohort than in the comparison cohort (12.1 versus 4.84 per 1000 @entity1 -years). Compared to non- @entity565 subjects, the adjusted hazard ratio (aHR) of @entity27 increased to 1.78 for @entity565 @entity1 with one or less annual emergency room (ER) visit, and 23.8 for those who visited ER more than once per year. In addition, aHR in @entity1 with inhaled @entity479 treatment compared to those without @entity479 treatment was 1.33 (95% CI = 1.01-1.76). CONCLUSION: @entity1 with @entity565 have a significantly higher risk of developing @entity27 than the general population. The results suggest that the risk of @entity27 is proportional to @entity565 control and @entity1 with inhaled @entity479 treatment have a higher risk for @entity27 than those without @entity479 treatment.
