A prospective study of negative pressure wound therapy with integrated irrigation for the treatment of XXXX .

@entity1 @entity6 @entity281 @entity922 @entity4760
OBJECTIVE: @entity1 with @entity6 often present with pedal wounds resistant to standard wound healing modalities and become chronic in nature. These chronic wounds in @entity6 @entity1 have a high incidence of complications including @entity281 and amputation. Negative pressure wound therapy has been found to facilitate healing of the stagnant pedal wound. This protocol was designed to determine wound closure rates using a unique negative pressure wound therapy system that delivers vacuum-assisted wound closure with a simultaneous irrigation feature (Svedman Wound Treatment System). METHODS: A prospective single center study was conducted in adults with @entity4760 >= cm(2) or more in size showing no signs of @entity922 , and having adequate blood flow. @entity1 received dressing changes and irrigation on a standard regimen with weekly wound assessments for a minimum of 6 weeks. RESULTS: 11 @entity1 and 8 @entity1 with a mean wound size of 2.4 cm   2.2 cm were treated with the device. A total of 14 of /19 (74%) @entity1 healed completely, with a median healing time of 34 days (range, 9-114). Eleven of 19 @entity1 (58%) healed within the 6-week evaluation period. For the 5 @entity1 who did not heal completely with the device, other treatments were utilized, including further wound debridement, muscle flaps, and skin grafting procedures. CONCLUSIONS: Negative pressure wound therapy with integrated irrigation was well tolerated by the @entity1 without complications related to the device application or irrigation feature. The data clearly suggests that this technology may be a promising alternative for the chronic nonhealing @entity6 wound.
