Results of therapy in stage IV-S @entity521 with massive XXXX .

@entity1 @entity382 @entity1310 @entity5 @entity83 @entity764 @entity354 @entity521 @entity1575
To document the incidence and severity of symptomatic @entity382 in @entity1 with @entity5 , we reviewed the charts of @entity1 with @entity521 seen at @entity1 's Hospital of Pittsburgh between 1951 and 1985. Sixteen met the criteria for IV-S disease, and 11 of these (69%) had massive @entity382 . Five @entity1 had symptoms referable to their liver size including respiratory distress, @entity354 , or decreased urine output. Liver function appeared to be normal or only mildly abnormal in the 9 @entity1 where data were available. Because therapy was so variable, it was not possible to correlate treatment regimen with outcome. However, 3 symptomatic @entity1 who received less than or equal to 600 rad without chemotherapy had prompt subjective responses. Follow-up was available on 10 @entity1 6 months-18 years (median 18 years) from diagnosis. Eight were alive with resolved or resolving @entity382 . High dose (greater than or equal to 3,300 rad) radiation-related side effects included multiple rib @entity83 , @entity764 in one @entity1 , and @entity1310 with @entity1575 resulting in death of a second @entity1 . Our results support prior recommendations that for symptomatic @entity382 , low doses of radiation be considered.
