Clinical outcome of XXXX .

@entity1 @entity1582 @entity3061 @entity9236 @entity8709
BACKGROUND AND OBJECTIVE: The aim of this study was a retrospective analysis of the presenting features of @entity8709 , its response to therapy and its clinical course. DESIGN AND METHODS: Forty-six cases diagnosed between August 1970 and June 1993 were carefully reviewed. The follow-up was continued until June 1998 and the median observation time was 118 months. RESULTS: The disease was most frequently localized in the upper airways (37/46; 80%), with the mass limited to a single site in all but seven @entity1 in whom two contiguous sites were involved. Other localizations were the lymph nodes, thyroid, skin, stomach, and brain. The clinical symptoms were related to the site of presentation, and the median time between appearance and diagnosis was 7.5 months. The median age at diagnosis was 55 years (range 16-80), with 14 @entity1 (30%) being under 50 years old. The disorder was approximately twice as common in males as in females. Ten @entity1 (21%) had a monoclonal component. The therapeutic strategy varied, although the most frequent form of treatment was local radiotherapy. Thirty-nine @entity1 (85%) achieved complete remission (CR), five (11%) a partial remission (PR) and two (4%) did not respond to therapy (NR). Local recurrence (LR) or recurrence at other sites (ROS) occurred in 7.5% and 10%, respectively. Seven @entity1 (15%) developed @entity1582 ( @entity1582 ), characterized by multiple sites of @entity3061 in almost all cases with soft tissue involvement in some of them. The 15 year survival rate was 78%. INTERPRETATION AND CONCLUSIONS: This review of a relatively large series of @entity1 confirms the favorable prognosis of @entity9236 when treated locally by irradiation and/or surgery.
