The effect of audio therapy to treat postoperative pain in XXXX undergoing major surgery: a randomized controlled trial.

@entity1 @entity158 @entity146
PURPOSE: To evaluate the analgesic effect of music and audiobooks in @entity1 undergoing major surgical procedures when compared to a control (silence) group. METHODS: The study was a prospective and randomized trial. @entity1 undergoing major surgeries were randomized to one of the three groups: music, audiobook or control (silence). The primary outcome was the @entity158 burden reduction by two treatments within 48  h postoperatively. @entity158 burden was measured using the area under the @entity158 scale versus the 30  min interval for each treatment. RESULTS: 60 @entity1 were recruited and 56 completed the study. @entity158 burden was @entity146 compared to control, median (IQR) of -60 (-90 to 0), -45 (-90 to 0) and 0 (-30 to 90) (min  *  @entity158 score), respectively, P  =  0.04. A linear regression analysis demonstrated an independent group effect on @entity158 reduction even after adjusting for the mean @entity158 scores recorded at the beginning of the treatment, slope of regression line -56.8      24 goodness of fit r (2)  =  0.25 and slope significantly different from 0 (P  =  0.02). CONCLUSIONS: Audio therapy is an efficacious adjunct method to decrease post-surgical @entity158 in @entity1 undergoing major surgeries. Audio therapy should be considered as an important strategy to minimize @entity158 in @entity1 undergoing major surgery.
