XXXX , @entity391 , and heartburn in pregnancy: a prospective look at risk, treatment, and outcome.

@entity1 @entity1085 @entity390 @entity391 @entity344 @entity1017
OBJECTIVE: To examine risk factors, treatment, and outcomes for @entity390 / @entity391 (N/V) and heartburn during pregnancy. METHODS: We included 2731 @entity1 from a prospective cohort study of @entity1085 in pregnancy. Subjects completed questionnaires at enrollment, early third trimester, and 4-6 weeks postpartum. We used logistic regression to examine independent predictors of @entity344 . RESULTS: Ninety-five percent of pregnant @entity1 experienced either heartburn and/or N/V. Independent predictors for heartburn included prepregnancy heartburn (OR 5.28, 95% CI 3.78-7.37), multigravidity, prepregnancy body mass index, and pregnancy @entity1017 . Independent predictors for N/V included prepregnancy N/V (OR 2.25, 95% CI 1.52-3.31), other digestive problems prepregnancy, younger age, single gestation, and carrying a female fetus. 11% of @entity1 with N/V and 47% of @entity1 with heartburn used pharmacologic therapy. @entity1 born to @entity1 with heartburn had significantly higher birth weights (p = 0.03), but gestational age at delivery was not significantly different. N/V was not associated with birth weight or gestational age at delivery. 19.7% of @entity1 with heartburn during pregnancy reported postpartum heartburn. CONCLUSIONS: Heartburn and N/V are common pregnancy symptoms, particularly among @entity1 with a history of such symptoms. Neither condition appears to adversely affect the outcome of pregnancy. Pregnancy-related heartburn predisposes to early postpartum heartburn.
