Correlation of standard diffusion-weighted imaging and diffusion kurtosis imaging with distant metastases of XXXX .

@entity1 @entity5 @entity189 @entity3
PURPOSE: To investigate the correlation of standard diffusion-weighted imaging (DWI) and diffusion kurtosis imaging (DKI) with distant metastases of @entity189 . MATERIALS AND METHODS: Fifty-eight @entity1 with @entity189 (27 with distant @entity3 and 31 with no @entity3 ) were included in this study. The apparent diffusion coefficient (ADC) value from standard DWI (b values of 0 and 1000 sec/mm(2) ), Dapp , and Kapp from DKI (b values of 0, 700, 1400, and 2000 sec/mm(2) ) were acquired with a 3.0T magnetic resonance imaging (MRI) scanner. These quantitative parameters were calculated from the entire @entity5 . Receiver operating characteristic curve analyses were conducted to assess the utility for discrimination of @entity5 with distant @entity3 and those without @entity3 . Parameters were compared using the independent-samples t-test. RESULTS: The histogram metrics 10th percentile of Dapp (Dapp-10th ) and ADC values (ADC10th ) were significantly lower in the distant @entity3 group than those without @entity3 (972.5        118.8 vs. 1121.3        133.8   *   10(-6) mm(2) /s, P   =   0.03; 809.2        67.1 vs. 856.2        72.1   *   10(-6) mm(2) /s, P   =   0.03). Dapp-10th showed relatively higher area under the curve (AUC) (0.856 vs. 0.669, P   =   0.024), and higher specificity (100% vs. 68%) than ADC10th did for differentiation of lesions with distant @entity3 from those without @entity3 . CONCLUSION: DKI was relatively better than standard DWI in discriminating @entity189 with distant @entity3 from those without @entity3 . J. Magn. Reson. Imaging 2015.
