XXXX in Piau  : comparison with features observed in other regions of Brazil.

@entity1 @entity981 @entity10707 @entity3232 @entity3052
Differences in age and sex distribution as well as FAB (French-American-British classification) types have been reported for @entity3052 in several countries. We studied the demographics and response to treatment of @entity1 with @entity3052 ( @entity3052 ) and @entity981 ( @entity981 ) between 1989 and 2000 in Teresina, Piau , and compared these results with reports from Brazil and other countries. Complete data concerning 345 @entity1 (230 @entity981 , 115 @entity3052 ) were reviewed. @entity3052 occurred predominantly in adults (77%), with a median age of 34 years, similar to that found in the southeast of Brazil but lower than the median age in the United States and Europe (52 years). FAB distribution was similar in @entity1 and adults and @entity10707 was the most common type, as also found in Japan. The high frequency of @entity3232 described in most Brazilian studies and for Hispanics in the United States was not observed. Overall survival for adults was 40%, similar to other studies in Brazil. A high mortality rate was observed during induction. No clinical or hematological parameter influenced survival in the Cox model. @entity981 presented the characteristic peak of incidence between 2-8 years. Most of the cases were CD10+ pre-B @entity981 . In 25%, abnormal expression of myeloid antigens was observed. Only 10% of the @entity1 were older than 30 years. Overall survival was better for @entity1 . Age and leukocyte count were independent prognostic factors. These data demonstrate that, although there are regional peculiarities, the application of standardized treatments and good supportive care make it possible to achieve results observed in other countries for the same chemotherapy protocols.
