XXXX : a clinicopathological study of 16 Chinese cases.

@entity1 @entity548 @entity5 @entity5426 @entity2279 @entity21468 @entity2280
AIMS: To review retrospectively 16 cases of @entity5426 ( @entity5426 ) with emphasis on their clinical and pathological characteristics, treatment and possible prognostic factors. METHODS AND RESULTS: All eligible cases were searched and acquired from archives of the pathology departments of two hospitals in Shanghai, The Fifth @entity1 's Hospital of Shanghai, Fudan University, and the Shanghai Cancer Center, Fudan University, China. The @entity1 ranged in age from 19 to 77 years, and 5 @entity1 were below 50 years of age. Microscopically, the @entity5 were mostly composed of large, round or polygonal epithelioid cells that were predominantly arranged in solid sheets or nests. The @entity5 cells had basophilic or eosinophilic cytoplasm, vesicular nuclei, and prominent nucleoli. Mitotic figures including abnormal mitoses were frequently encountered. In all 16 cases in our series, immunohistochemical studies showed positivity for @entity2279 , and partial positivity for @entity21468 , @entity2280 and factor VIII-related antigen. Of the 14 @entity1 available for follow-up, 3 @entity1 were alive with disease, 9 @entity1 died as a result of the @entity5 , 1 died of local @entity548 , and one died of unknown etiology. The median survival was 17.1 months. CONCLUSIONS: EA is highly aggressive and carries a very poor prognosis. Therefore, the clinical recognition and correct diagnosis of EA are essential.
