The association of impaired neutrophil XXXX with postoperative surgical @entity295 .

@entity1 @entity6722 @entity295 @entity5 @entity86
@entity86 remains a major problem in current surgical practice. This study assesses the predictive role of neutrophil @entity6722 in the development of @entity295 in surgical @entity1 . Neutrophil @entity6722 was measured in 30 @entity5 @entity1 undergoing gastrointestinal surgery and in 26 healthy age and sex-matched controls. Neutrophil @entity6722 was significantly reduced (P less than 0.02) in the @entity1 (mean 79.2 micron +/- 2.7 s.e.m.) compared with the controls (mean 86.8 micron +/- 1.9 s.e.m.). In the entire @entity1 group neutrophil @entity6722 did not change to any appreciable extent following surgery. However, in the seven @entity1 who developed postoperative septic complications, @entity6722 , which was similar to control levels in the pre-operative stage, declined significantly following surgery. Pre-operative values for the septic group of @entity1 are 92.4 micron +/- 4.02 s.e.m.. These declined to 73.4 micron +/- 3.15 s.e.m. (P less than 0.05) and to 68.2 micron +/- 2.89 s.e.m. (P less than 0.05), 5-8 days (early) and 10-14 days (late) postoperatively respectively. Neutrophil @entity6722 in the non-septic group of @entity1 did not alter over this same period. The data suggest that the onset of @entity86 in @entity1 is accompanied by impairment of chemotactic properties in their neutrophils. However, it is also evident that measurement of this variable in @entity1 before operation does not help to define an 'at risk' group for the development of @entity86 .
