XXXX receptor beta expression in @entity5123 of the parotid gland.

@entity1 @entity1782 @entity2931 @entity5 @entity1783 @entity5123
AIMS: @entity5123 of the salivary gland have gender and age distributions suggesting that @entity2931 has a causal role. However, @entity2931 receptor (ER)alpha is expressed at low levels in normal salivary gland tissues and data from @entity5 are conflicting. There is preliminary evidence that the recently described @entity1783 may be the major ER in salivary gland tissue. The aim of this study was to determine the nature and extent of @entity1783 expression in @entity5123 of the salivary gland. METHODS: @entity5123 and normal tissues of the parotid gland from 49 @entity1 were tested for @entity1782 and @entity1783 expression by semiquantitative immunohistochemistry. Associations were sought with @entity1 age and gender. RESULTS: @entity1782 and @entity1783 expression was localised mainly to the nuclei of ductal cells in normal tissues and the epithelial components in @entity5123 . Within each tissue and receptor type there were no associations between ER positivity and @entity1 age or gender. @entity1783 was expressed in almost twice as many normal tissues and @entity5123 as @entity1782 . Expression of @entity1783 was also significantly higher in @entity5 compared with normal tissues. CONCLUSIONS: This is thought to be the first study of @entity1783 in @entity5123 of the salivary gland. Findings support @entity1783 as the major ER in salivary glands, and provide evidence that @entity1783 may have a role in the development of @entity5123 of the salivary gland.
