Effect of @entity8 -reperfusion on @entity651 and inflammatory responses in male XXXX .

@entity1 @entity8 @entity1976 @entity63 @entity39 @entity1711 @entity1505 @entity651 @entity1710 @entity810 @entity35
OBJECTIVES: @entity810 ( @entity810 ), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized @entity1 . @entity8 -reperfusion, one of the main causes of @entity810 , is of particular importance in the setting of kidney transplantation. MATERIALS AND METHODS: Sixty male @entity35 were divided into four groups including control, nephrectomy, sham surgery and @entity8 -reperfusion (IRI) group. The @entity35 were anesthetized with intraperitonealketamin and xylazin. For making IRI group, right nephrectomywas performed, and after a week, the left kidney pedicle was occluded for 45 min for making @entity63 that followed by 24 hr reperfusion. At the end of reperfusion phase, the lung tissues were isolated to be used in immunohistochemical and histological assays. Immunohistochemical assay was used to evaluate @entity1976 and @entity1505 , and @entity1710 - @entity1711 staining assay was used to histopathology. RESULTS: lung tissues injury after @entity8 -reperfusion was revealed by immunohistochemistry analysis to increase @entity1505 level and decrease @entity1976 (an anti-apoptotic protein) level. @entity651 and @entity39 was discovered by @entity1710 - @entity1711 staining to be more evident in IRI group than sham and control groups. CONCLUSION: The results demonstrated that increase in @entity1505 and decrease in @entity1976 levels in lungs induces the pulmonary inflammatory damage in renal IRI model.
