XXXX : US-guided percutaneous radiofrequency ablation--intermediate and long-term survival rates.

@entity1 @entity0 @entity39 @entity5 @entity3
PURPOSE: To retrospectively assess the local control and intermediate- and long-term survival of @entity1 with liver metastases from @entity0 who have undergone percutaneous ultrasonography (US)-guided radiofrequency (RF) ablation. MATERIALS AND METHODS: This study was approved by the hospital ethics committee, and all @entity1 provided written informed consent. RF ablation was used to treat 87 @entity0 (mean diameter, 2.5 cm) in 52 female @entity1 (median age, 55 years). Inclusion criteria were as follows: fewer than @entity5 , maximum @entity5 diameter of 5 cm or smaller, and disease either confined to the liver or stable with medical therapy. Forty-five (90%) of 50 @entity1 had previously undergone chemotherapy, hormonal therapy, or both, and had no response or an incomplete response to the treatment. Contrast material-enhanced computed tomography and US were performed to evaluate complications and technical success and to assess for local @entity5 progression during follow-up. The Kaplan-Meier method was used to assess survival, and results were compared between groups with a log-rank test. Cox regression analysis was used to assess independent prognostic factors that affected survival. RESULTS: Complete @entity5 @entity39 was achieved in 97% of @entity5 . Two (4%) minor complications occurred. Median time to follow-up from diagnosis of liver @entity3 and from RF ablation was 37.2 and 19.1 months, respectively. Local @entity5 progression occurred in 25% of @entity1 . New intrahepatic metastases developed in 53% of @entity1 . From the time of first RF ablation, overall median survival time and 5-year survival rate were 29.9 months and 27%, respectively. From the time the first liver @entity3 was diagnosed, overall median survival time was 42 months, and the 5-year survival rate was 32%. @entity1 with @entity5 2.5 cm in diameter or larger had a worse prognosis (hazard ratio, 2.1) than did @entity1 with @entity5 smaller than 2.5 cm in diameter. CONCLUSION: Survival rates in selected @entity1 with @entity0 treated with RF ablation are comparable to those reported in the literature that were achieved with surgery or laser ablation.
