[ XXXX according to age].

@entity1 @entity146 @entity1066 @entity3 @entity320
UNASSIGNED: In recent years the incidence of @entity320 in elderly @entity1 has increased with an unfavorable oncologic outcome due not only to immune deterioration but also to greater @entity146 . The aim of this study was to evaluate the behavior of cutaneous @entity320 in relation to age. A consecutive series of cases with @entity320 operated in a reference center in the period 2001-2013 was included. The sample was divided into two groups according to the age. Group 1 (G1): under 65 years and Group 2 (G2): over 65 years. Histopathological variables and oncologic outcomes were compared between the two groups. Three hundred and eighty eight @entity1 were operated. They belonged to G1 241 (62%) and to G2 147 (38%). Both groups were homogeneous with respect to the histological type of @entity320 . Group 2 had thicker @entity320 (Breslow > 4 mm 19% vs. 7%, p < 0.005) and higher rates of @entity1066 (37% vs. 20%, p: 0.007) and distant @entity3 (stage IV 11% vs. 3%, p 0.01). There was no difference between groups regarding nodal involvement. With a mean follow up of 45 (6-98) months throughout the series, recurrence of disease was higher in group 2 (26% vs. 17%, p: 0.03), but the specific mortality showed no significant difference (9.5% vs. 5.3%, p: 0.12). In conclusion, cutaneous @entity320 in @entity1 over 65 years is more aggressive with higher rates of local recurrence and distant @entity3 .
