Late stage and grave prognosis of XXXX in Thailand.

@entity1 @entity3332 @entity6552 @entity5 @entity957 @entity418 @entity2210 @entity1282 @entity420
BACKGROUND: @entity418 is one of the major health concerns in Southeast Asian countries, including Thailand. However, only a limited number of studies have been reported from this region. This study was designed to evaluate the prevalence, clinical characteristics and survival rate of @entity418 in Thailand. MATERIALS AND METHODS: Clinical information, histological features and endoscopic findings were collected from a tertiary care center in central region of Thailand between September 2011- November 2014 and reviewed. RESULTS: A total of 64 @entity418 @entity1 including 58 @entity1 and 6 @entity1 with mean age of 62.6 years were enrolled. Common presenting symptoms were @entity1282 (74%), @entity2210 (10%) and @entity6552 (8%). Mean duration of symptoms prior to diagnosis was 72 days. @entity3332 with contact bleeding was the most common endoscopic finding (55.6%). The location of @entity5 was found in proximal (16%), middle (50%) and distal (34%) esophagus. @entity957 was far more common histology than @entity420 (84.2% vs 10.5%). However, @entity420 was significantly more common than @entity957 in distal area of esophagus (100% vs 22.9%; p=0.0001, OR=1.6, 95%CI=1.1-2.2). @entity418 stages 3 and 4 accounted for 35.2% and 59.3% respectively. Overall 2-year survival rate was 20% and only 16% in metastatic @entity1 . CONCLUSIONS: Most @entity418 @entity1 in Thailand have @entity957 and nearly all present at advanced stage with a grave prognosis. Screening of high risk individuals and early detection might be important keys to improve the survival rate and treatment outcome in Thailand.
