Reopening of the gastroduodenal pylorus after its closure in XXXX .

@entity1 @entity254 @entity1661 @entity7502 @entity6886 @entity397 @entity35 @entity356 @entity130
BACKGROUND: @entity130 occurs in 3% to 12% of @entity1 with @entity1661 . The best procedure to treat major @entity397 continues to be a challenge. The purpose of the present study was to analyze differences between the time of gastroduodenal pylorus reopening after its closure with different suture materials and to verify the influence of vagotomy on local tissue changes. METHODS: Thirty @entity35 were submitted to closure of the gastroduodenal pylorus and gastrojejunal @entity254 . The animals were divided into three groups (n = 10) according to the type of suture material used: plain catgut, @entity6886 , and @entity7502 . Half of the animals in each group (n = 5) were also submitted to truncal vagotomy. Postoperative assessment included weekly abdominal X-ray following intragastric contrast injection until re-establishment of the gastroduodenal transit or for a maximum period of 4 wk. At the end of the follow-up period, the pyloric regions and the gastrojejunal @entity254 were removed for histological analysis. The groups were compared by the Kaplan-Meier test, with the level of significance set at P < 0.05. RESULTS: The @entity7502 suture maintained the pylorus closed for a longer period of time (36.3 +/- 11.6 d) (P < 0.05). No difference was observed between the @entity6886 suture (25.8 +/- 14.2 d) and the plain catgut suture (18.7 +/- 10.2 d). Vagotomy did not influence the time of pyloric reopening, but was associated with a less intense gastric inflammatory reaction. CONCLUSIONS: The nonabsorbable suture was the most adequate for exclusion of pyloric transit. Vagotomy had no influence on the time of pyloric reopening but reduced @entity356 .
