[Relation between XXXX ( @entity470 ) and @entity876 expression and radiocurability of laryngeal squamous cell cancer].

@entity1 @entity5 @entity470 @entity2802 @entity876
Radiotherapy and surgery are the most important treatment modalities for the majority of @entity5 . Because of high efficacy and better organ preservation radiotherapy is generally preferred for early and intermediate stage of the disease. Some of @entity1 with more locally advanced @entity5 can still be cured by means of radiotherapy, but we have not got reliable prognostics factors for predicting radiocurability. THE AIM OF MY STUDY: was to investigate the value of @entity876 and @entity470 expression for predicting clinical outcomes of @entity5 @entity1 treated with radiotherapy. METHODS AND MATERIALS: The study included 50 @entity1 with @entity5 treated in Department of Radiotherapy of Silesian Oncology Center between the years 1998 and 2003. Paraffin sections from archival material were studied immunohistochemically for detection @entity876 and @entity470 and correlated with clinical parameters and @entity5 control and @entity1 survival. RESULTS: Accumulation of @entity876 and @entity470 were detected in 65% and 50% of @entity5 respectively. No relationship was observed between immunostaining for investigated proteins and clinicopathologic factors. The @entity2802 @entity5 stage was the most significant prognostic factor for local control and overall survival. @entity876 was favorable prognostic factor with 5-years disease free survival rate 82% for @entity1 @entity876 -positive and 75% for @entity876 -negative @entity1 (p = 0.04). CONCLUSION: The @entity2802 @entity5 stage is the most important prognostic factor for @entity5 . Tumors accumulating @entity876 have better prognosis what indicates possibly role for @entity876 immunohistochemical analysis for predicting outcomes of radiotherapy in @entity1 with @entity5 .
