Impaired decision-making in symptomatic anorexia and @entity1279 XXXX : a meta-analysis.

@entity1 @entity1278 @entity1277 @entity1279 @entity5550
BACKGROUND: Impaired decision-making is a potential neurocognitive phenotype of @entity1277 . It is therefore important to disentangle the decision-making deficits associated with the @entity1277 subtypes and determine whether this putative impairment is a state or trait marker of the disease or more related to starvation. We systematically reviewed the literature on decision-making in @entity1277 and conducted a meta-analysis to explore its role in @entity1278 ( @entity1278 ), @entity1279 ( @entity1279 ) and @entity5550 ( @entity5550 ). METHOD: A search of the Medline and EMBASE databases and article references was performed. A total of 23 studies (2044 @entity1 ) met the selection criteria. When the Iowa gambling task (IGT) was used in at least three of the studies, a meta-analysis was run. RESULTS: IGT performance was significantly worse in @entity1 with an @entity1277 diagnosis ( @entity1278 , @entity1279 or @entity5550 ) compared with healthy controls, indicating that @entity1277 have a negative effect on decision-making. Hedges' g effect sizes were moderate to large (-0.72 in @entity1278 , -0.62 in @entity1279 , and -1.26 in @entity5550 ). Recovered @entity1278 @entity1 had IGT scores similar to those of healthy controls. Restrictive @entity1278 @entity1 had significantly lower IGT net scores than purging @entity1278 @entity1 , and both @entity1278 subtypes had worse performances than healthy controls. Age and body mass index did not explain results. CONCLUSIONS: Decision-making was significantly altered in @entity1 with @entity1277 . Poor decision-making was more pronounced during the acute phase than in the recovered state of @entity1278 . Nutritional status during the acute phase of the disease did not seem to influence decision-making skills.
