Diagnostic Value of Biopsy Techniques in Lumbar XXXX : Percutaneous Needle Biopsy and Open Biopsy.

@entity1 @entity1398 @entity1512
OBJECTIVE: The objective of this study was to evaluate and compare the diagnostic value of the open biopsy technique and the percutaneous biopsy techniques in @entity1512 . METHODS: Between January 2004 and December 2009, we retrospectively reviewed the medical records of 57 @entity1 with @entity1512 . The etiologic diagnosis of the @entity1512 was obtained by two methods. Of 57 cases, twenty-seven @entity1 underwent open biopsy and thirty @entity1 underwent percutaneous needle biopsy including computed tomography (CT) - guided and fluoroscopy-guided needle aspiration. All biopsies were performed by experienced two neurosurgeons and one interventional radiologist. RESULTS: Of the 57 cases radiologically consistent with spinal infection, 29 (50.9%) biopsy specimens resulted in positive cultures and 28 (49.1%) returned negative cultures. According to the type of biopsy techniques, the culture-positive rate was higher (p=0.005) in the open biopsy group than the percutaneous needle biopsy group. 19 (70.4%) of 27 biopsy specimens were positive in the open biopsy group, and 10 (33.3%) of 30 biopsy specimens were positive in the percutaneous needle biopsy group. Furthermore, the open biopsy showed higher positive culture rate than the percutaneous needle biopsy in cases with administration of empirical antibiotics although there was no statistically significant (p=0.137). CONCLUSIONS: Open biopsy should be considered for administration of organism-specific antibiotics for the successful treatment when percutaneous needle yield negative result. Furthermore, empirical antibiotics should be delayed until results of cultures unless the @entity1 is severely septic, critically ill, @entity1398 or neurologically compromised.
