@entity23694 is a prognostic factor in XXXX .

@entity1 @entity23694 @entity15
@entity23694 ( @entity23694 ) predicts a worse evolution in the first stages of @entity15 ( @entity15 ). The aim of this study was the follow-up of a group of relapsing-remitting @entity15 @entity1 for a longer time to evaluate whether the @entity23694 implies a poor prognosis. Oligoclonal IgM bands were performed in 29 @entity15 @entity1 followed up from 5 to 16 years. Time to conversion to secondary-progressive @entity15 (SPMS), time elapsed to reach a disability of 6 in the Expanded Disability Status Scale (EDSS), percentage of @entity1 with a benign @entity15 , and changes in EDSS score were evaluated. During the follow-up, 70.8% of @entity1 with @entity23694 converted to SPMS. None of the @entity1 without @entity23694 did. At the end of the study, 63.6% of @entity1 with @entity23694 had reached EDSS 6, whereas none of the @entity1 lacking @entity23694 reached values above EDSS 3. When @entity1 with benign @entity15 were analyzed, 82% lacked @entity23694 . All @entity1 with a nonbenign @entity15 had @entity23694 . At the end of the study, the mean EDSS score was 4.64 in @entity1 with @entity23694 and 1.31 in those without. The presence of oligoclonal IgM bands in cerebrospinal fluid is an unfavorable prognostic marker in @entity15 .
