Effect of XXXX on endostatin levels in @entity2479 /reperfusion injury.

@entity2479 @entity840 @entity2816 @entity63
AIM: To evaluate the effects of @entity2816 treatment on endostatin production in @entity63 /reperfusion-injured @entity840 retinas. METHODS: Control, @entity63 , @entity2816 / @entity63 groups including 7 animals in each were formed from pigmented male @entity840 . @entity2479 was induced by cannulating anterior chambers and lifting the bottle to a height of 205 cm for 90 min in the @entity63 and @entity2816 / @entity63 groups. The @entity2816 / @entity63 group received @entity2816 (300 mg/kg/day) via nasogastric tube 24 h before @entity63 and during 7 days of reperfusion. @entity840 were sacrified for biochemical analysis of retinal endostatin level by ELISA. RESULTS: The mean retinal endostatin levels of the control, @entity63 and @entity2816 / @entity63 groups were 11.79 +/- 7.36, 14.70 +/- 4.88, 30.94 +/- 15.59 ng/ml, respectively. The mean retinal endostatin level of the @entity2816 / @entity63 group was significantly higher than that of the control group (p = 0.011). The mean retinal endostatin level of the @entity2816 / @entity63 group was higher than that of the @entity63 group, but there was no statistically significant difference (p = 0.073). No statistically significant difference in the mean retinal endostatin level was found between the control and @entity63 groups (p = 0.165). CONCLUSION: @entity2816 treatment increased retinal endostatin level in @entity63 /reperfusion-injured @entity840 retinas.
