XXXX of @entity164 in Taiwan: a morphometric and genetic study.

@entity1 @entity508 @entity4610 @entity1897 @entity12289 @entity164 @entity6447 @entity3519
@entity164 ( @entity164 ) is a dominantly @entity6447 associated with @entity508 , @entity4610 , @entity3519 and @entity1897 . Presented here are 5 @entity164 cases. A morphometric analysis of the histopathology of their sural nerves was carried out to know the relationship between axon size and myelin thickness. @entity164 cases were identified by polymerase chain reaction. On the basis of the clinical symptoms, there was 1 type I, 2 type II and 2 type III @entity1 . The sural nerves were biopsied for single-fiber, ultrastructural and morphometric analysis. Morphometric parameters such as fiber and axon sizes, myelin thickness and g ratio (axon diameter:fiber diameter) were estimated. The pathological features of the sural nerves in the 2 type III and 1 of the type II @entity1 revealed a loss of myelinated and unmyelinated fibers, and the morphometry studies showed a decreased fiber density, the loss of large myelinated fibers, a smaller size of the axons with thinner myelin sheaths and an increased percentage of myelinated fibers with a g ratio (axon diameter:fiber diameter) above 0.7. However, only subtle pathological changes were noted in the type I @entity1 and the remaining type II @entity1 . Our findings suggested that there is a loss of large myelinated fibers and distal axonopathy with relative @entity12289 of @entity1 with @entity164 .
