Some cytokine profiles of T-helper cells in lesions of advanced XXXX .

@entity1 @entity650 @entity404 @entity2520 @entity379 @entity2521 @entity1199 @entity3646
OBJECTIVE: The aim of the present study was to analyze some cytokine profiles of T-helper cells in @entity2520 . MATERIAL AND METHODS: 22 adult @entity1 (7 females and 15 males, aged 24-66 years) with advanced and generalized chronic @entity2521 were recruited. Clinical and radiographical characteristics of periodontal disease was assessed. From each @entity1 a gingival biopsy was obtained from one randomly selected diseased interproximal site. The soft tissue sample was prepared for immunohistochemical analysis. Double staining was performed to detect cells positive for both the @entity404 marker and different cytokines, i.e. @entity1199 , @entity3646 , @entity650 and @entity379 ( @entity379 ). RESULTS: The lesions in advanced @entity2521 contained similar proportions of cells positive for the different cytokine markers examined. In addition, the number of cells expressing cytokine profiles for either T helper-1 ( @entity379 + @entity1199 ) or T helper-2 ( @entity3646 + @entity650 ) was similar. CONCLUSION: It is suggested that the lesions of @entity2521 are regulated by a combined Th-1 and Th-2 function.
