Biocompatibility of a XXXX -coating method for denture base acrylic resin.

@entity1 @entity4625 @entity146 @entity840 @entity95 @entity8670 @entity6701 @entity3759
OBJECTIVES: Ease of denture cleaning is of paramount importance in geriatric @entity1 and those with limited dexterity. We have previously investigated methods of coating dentures with @entity6701 ( @entity3759 ) and reported the effects (self-cleaning and antibacterial) of such treatments in in  vitro studies. This study was to verify the biocompatibility of a @entity3759 -coated acrylic resin produced by the new coating method with spray-coating technique. METHODS: Specimens were prepared from denture base acrylic resin and polished up to grit #1000. The @entity3759 -coating agent was sprayed onto the specimens using an airbrush gun. Specimens were then divided into ' @entity4625 (PMMA)', 'primer-coated PMMA' and ' @entity3759 -coated PMMA' groups to be evaluated for biological safety using a hamster oral mucosa @entity146 test, a @entity840 skin sensitisation test and a @entity95 intracutaneous test. The biological reaction was scored. RESULTS: Reaction scores were considerably <1.0, the acceptable limit set by the @entity8670 , in all three tests. Indeed, in most samples, there was no deleterious effect at all. CONCLUSION: These results tested on animals demonstrate that denture base resin coated with @entity3759 by this method does not cause @entity146 or sensitisation of the oral mucosa, skin or intracutaneous tissue and is therefore good biocompatibility for use in close proximity to oral mucosa and skin.
