A 3D Polymer Model for Future Nutrition Design Novel Nutrition Approach for @entity1577 , @entity31 and XXXX .

@entity1 @entity31 @entity29 @entity3147 @entity30 @entity1577
INTRODUCTION: @entity1577 ( @entity1577 ), @entity31 ( @entity31 ), and @entity30 ( @entity30 ) manifest as various, multiple symptoms from malfunctioning and/or damaged gastrointestinal tract, which plague the @entity1 . These symptoms result from the dysfunctional expression products of the specific mutations of the genes, which either manifest upon birth ( @entity1577 ) or later in life in immuno-genetically susceptible individuals as @entity29 ( @entity29 ). They all may potentially lead to @entity3147 of the @entity1 . Since only correcting the mutated genes, may cure these diseases permanently, the works on the future safe gene therapies continue vigorously. However, provision of the necessary nutrients to the suffering @entity1 is the requirement for an effective, supportive care at present. In this realm, we have developed a model of the diseased gastrointestinal tract aimed to guide designing and testing various nutritional therapies. MATERIALS AND METHODS: It is well known that @entity29 induce crypts within the @entity1 ' gastrointestinal tract. Therefore, we have bioengineered, a novel, three-dimensional model of the gastrointestinal tract to evaluate the rheology of different types of nutrients. The model was assembled out of the bio-inert polymer tube with openings leading to vials of different shapes and sizes, as the simulation of the gastrointestinal tract altered by the diseases to contain multiple crypts. RESULTS AND CONCLUSIONS: The newly developed three-dimensional model effectively simulates the structure and functions of the gastrointestinal tract of the @entity1 with mild and severe @entity31 , @entity30 , and @entity1577 . This model should allow us to design and test different nutritional supplements, with properties complementing the pathologically altered by the diseases functionalities of the @entity1 ' gastrointestinal tracts. Therefore, it should help us to design the effective supportive therapies; thus to prevent the @entity1 ' @entity3147 .
