Mechanical Thrombectomy in XXXX : Systematic Review of 185 Cases.

@entity1 @entity51 @entity49 @entity1779
BACKGROUND AND PURPOSE: @entity49 is generally treated with anticoagulation. However, some @entity1 do not respond to medical therapy and these might benefit from mechanical thrombectomy. The aim of this study was to gain a better understanding of the efficacy and safety of mechanical thrombectomy in @entity1 with @entity49 , by performing a systematic review of the literature. METHODS: We identified studies published between January 1995 and February 2014 from PubMed and Ovid. We included all cases of @entity49 in whom mechanical thrombectomy was performed with or without intrasinus thrombolysis. Good outcome was defined as normal or mild @entity51 at discharge (modified Rankin Scale, 0-2). Secondary outcome variables included periprocedural complications and recanalization rates. RESULTS: Our study included 42 studies (185 @entity1 ). Sixty percent of @entity1 had a pretreatment @entity1779 and 47% were stuporous or comatose. AngioJet was the most commonly used device (40%). Intrasinus thrombolysis was used in 131 @entity1 (71%). Overall, 156 (84%) @entity1 had a good outcome and 22 (12%) died. Nine (5%) @entity1 had no recanalization, 38 (21%) had partial, and 137 (74%) had near to complete recanalization. The major periprocedural complication was new or increased @entity1779 (10%). The use of AngioJet was associated with lower rate of complete recanalization (odds ratio, 0.2; 95% confidence interval, 0.09-0.4) and lower chance of good outcome (odds ratio, 0.5; 95% confidence interval, 0.2-1.0). CONCLUSIONS: Our systematic review suggests that mechanical thrombectomy is reasonably safe but controlled studies are required to provide a definitive answer on its efficacy and safety in @entity1 with @entity49 .
