A protective role of early collateral blood flow in @entity1 with XXXX .

@entity1 @entity583 @entity1188
Conflict persists regarding whether the presence of early collateral blood flow to the @entity1188 has an effective role in reducing @entity1188 size and improving myocardial salvage in @entity1 with @entity583 ( @entity583 ). We sought to investigate the impact of the collateral circulation on myocardial salvage and @entity1188 size in @entity583 @entity1 . METHODS: In 306 @entity1 who were diagnosed with @entity583 and underwent cardiac magnetic resonance within 1 week after revascularization, initial collateral flow to the @entity1188 was assessed by coronary angiography. Using cardiac magnetic resonance imaging, @entity583 size and salvage were measured. RESULTS: Among 247 @entity1 with preprocedural Thrombolysis in Myocardial Infarction flow 0/1, 54 (22%) @entity1 had good collaterals (Rentrop grade >= 2, Collateral Connection Score >= 2). @entity1188 size and area at risk were significantly smaller in @entity1 with good collaterals than those with poor collaterals ( @entity1188 size: 17.1  10.1 %LV vs 21.8  10.5 %LV, P = .003, area at risk: 33.8  16.8 %LV vs 38.8  15.5 %LV, P = .039). There was a significant difference of myocardial salvage index between 2 groups (50.9%    15.0% vs 43.8%    18.5%, P = .005). Poor collateralization was an independent predictor for large @entity1188 size (odd ratio 2.48 [1.28-4.80], P = .007). CONCLUSIONS: In @entity1 with @entity583 , the presence of well-developed collaterals to occluded coronary artery from the noninfarct vessel and its extent were independently associated with reduced @entity1188 burden and improved myocardial salvage. Our results help explain why MI @entity1 with well-developed collateralization have reduced mortality and morbidity.
