Genetic Analysis of XXXX @entity71283 Variant in Nonatherosclerotic Quasi-Moyamoya Disease.

@entity8731 @entity1 @entity66 @entity2791 @entity1378 @entity693 @entity2689 @entity7025 @entity60352 @entity731 @entity71283
BACKGROUND: @entity7025 ( @entity7025 ) and @entity7025 (definite @entity7025 ) have similar cerebral angiographic features, but whether these @entity66 have similar etiology or genetic background remains unclear. Recently, we have reported that the recently identified @entity7025 susceptibility gene variant @entity8731 @entity71283 ( @entity60352 ) was associated with @entity731 intracranial major @entity2791 /occlusion. The present study investigated the occurrence of @entity8731 @entity71283 in @entity1 with nonatherosclerotic quasi- @entity7025 . METHODS: This study was a 2-hospital-based case-control study conducted at the Department of Neurosurgery, The University of Tokyo Hospital and Kanto Neurosurgical Hospital. A total of 87 Japanese @entity1 who agreed to participate in this study were enrolled among both new and revisiting outpatients from October 2011 to December 2013 as follows: 78 @entity1 with definite @entity7025 and 9 @entity1 with nonatherosclerotic quasi- @entity7025 . RESULTS: The 9 @entity1 with nonatherosclerotic quasi- @entity7025 included 3 @entity1 with previous irradiation, 2 with @entity1378 , 1 with @entity2689 , 1 with @entity693 , 1 with Beh  et disease, and 1 with idiopathic @entity693 . The 78 @entity1 with definite @entity7025 included 66 @entity1 (84.6%) with the @entity71283 variant (64 heterozygotes and 2 homozygous). In contrast, no @entity1 with nonatherosclerotic quasi- @entity7025 had the variant. CONCLUSIONS: Nonatherosclerotic quasi- @entity7025 did not have @entity8731 @entity71283 variant. @entity7025 and @entity66 might be classified by genetic analysis of the @entity8731 @entity71283 genotype. Further larger studies are required to confirm the present findings.
