XXXX of salivary gland.

@entity1 @entity5 @entity4483 @entity14253 @entity1358 @entity3
We describe 11 @entity1 with a distinctive @entity14253 . Most of the @entity1 were adult @entity1 who presented with a painless mass. Nine @entity5 arose in minor salivary glands of the oral cavity (82%). Microscopically, they were characterized by the formation of trabeculae, cords, islands, and/or nests of monomorphic clear cells that were glycogen rich and mucin negative and were surrounded by hyalinized bands with foci of myxohyaline stroma. Cells with eosinophilic and granular cytoplasm were also noted. Both cell types showed minimal nuclear pleomorphism and a very low mitotic index. The @entity5 all had infiltrative borders. Immunohistochemically, the @entity5 cells expressed cytokeratins and epithelial membrane antigen, but not @entity4483 protein and smooth muscle actin. Ultrastructurally, the @entity5 cells contained abundant glycogen, desmosomes, peripheral tonofilaments, and prominent interdigitating microvilli without actin myofilaments or dense bodies. These immunohistochemical and ultrastructural findings provide evidence of epithelial differentiation without myoepithelial differentiation. For these @entity5 , we propose the name, @entity1358 ( @entity1358 ). These are low-grade malignant @entity5 . Two @entity1 had ipsilateral cervical lymph node @entity3 at presentation, but with surgical excision and either preoperative or post-operative radiotherapy in three cases, eight of 10 @entity1 with clinical follow-up are alive and well without evidence of recurrence. The mean clinical follow-up is 3.6 years, with a range of 6 months to 11 years. One @entity1 died as a result of surgery, another died of unrelated causes, and one @entity1 was lost to follow-up.
