XXXX saturation of the diet and plasma lipid concentrations, lipoprotein particle concentrations, and @entity165 efflux capacity.

@entity1 @entity844 @entity1675 @entity3294 @entity1718 @entity165
BACKGROUND: The @entity844 content and saturation degree of the diet can modulate HDL composition and @entity165 efflux. OBJECTIVE: We studied the modifications in plasma lipoprotein particles and serum capacity to stimulate @entity165 efflux induced by different @entity1718 . DESIGN: Seventeen @entity1 and 24 @entity1 followed in the same sequence 4 diets containing 35% of total energy as fat. The saturated fat diet contained 17% palm oil; the monounsaturated fat diet, 20.9% olive oil; the n-6 polyunsaturated fat diet, 12.5% sunflower oil; and the n-3 polyunsaturated fat diet, sunflower oil supplemented with 4-4.5 g fish oil/d. Each phase lasted 4-5 wk. RESULTS: In both sexes, @entity1675 concentrations were significantly lower with unsaturated fat diets than with the saturated fat diet, but concentrations of lipoproteins containing only @entity1675 (Lp A-I) were lower only in the @entity1 . Concentrations of lipoproteins containing both @entity1675 and @entity3294 (Lp A-I:A-II) were lower with both polyunsaturated fat diets in the @entity1 but significantly higher in the @entity1 . Lp E concentrations were significantly higher with the 2 polyunsaturated fat diets. Lp E non-B particle concentrations were not modified in the @entity1 but were significantly higher in the @entity1 in both polyunsaturated fat phases. Lp C-III concentrations were higher with the saturated fat diet only in the men. The serum samples taken after the n-3 polyunsaturated fat phase were the most efficient for extracting cellular @entity165 in both sexes. CONCLUSIONS: The monounsaturated and polyunsaturated fat diets were healthier, producing a better lipid profile. The n-3 polyunsaturated fat diet increased the capacity of serum to promote the efflux of @entity165 from cells in culture.
