Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with XXXX of the bile duct.

@entity43 @entity1 @entity4929 @entity5 @entity2225 @entity189 @entity14775 @entity3558 @entity652 @entity9296 @entity1125
@entity14775 of the liver has been a controversial entity, in particular, regarding differentiation from @entity4929 of the bile duct. In this study, we compared the characteristics of hepatic mucinous @entity43 (n=29) to those of cyst-forming @entity4929 of the bile duct (n=12). Radiological or macroscopic appearance, histological grade of @entity5 , and postoperative clinical course were recorded. Immunohistochemistry for biliary or gastrointestinal markers was performed to characterize cell phenotypes. The @entity1 with hepatic mucinous @entity5 were all female and ranged in age from 21 to 67 years, which was significantly younger than that in the @entity1 with @entity1125 . Eighteen mucinous @entity5 (76%) were located in the left lobe, with 13 (54%) in segment IV. @entity14775 were significantly larger than @entity4929 (median diameter: 110 vs 50 mm, P=0.008). In contrast to @entity4929 that were all histologically malignant, 26 mucinous @entity5 (90%) were @entity652 , 2 (7%) were borderline malignant, and 1 (3%) was a @entity189 in situ. Benign mucinous @entity9296 had the pure biliary immunophenotype, whereas gastrointestinal markers including @entity2225 and @entity3558 core proteins 2, 5AC, and 6 were more frequently expressed in borderline or malignant mucinous @entity5 and @entity1125 . There was no mortality in the @entity1 with mucinous @entity5 , whereas one @entity1 with @entity4929 died of @entity5 . In conclusion, hepatic mucinous @entity5 and @entity1125 have different clinicopathological characteristics as evidenced by differences in the age and gender of @entity1 , macroscopic appearance, immunophenotypes, and grades of @entity5 .
