XXXX in atherosclerotic renovascular disease: gradual changes 6 months after successful angioplasty.

@entity1 @entity8 @entity101 @entity2806 @entity2791 @entity194 @entity1011 @entity121
OBJECTIVE: To assess renal morphology using spiral computed tomographic angiography (CTA) before and 6 months after angioplasty of unilateral @entity2791 (RAS). METHODS: Spiral CTA scans from 14 @entity101 @entity1 (7 @entity1 ; mean age 57.4 +/- 13.1 years) with significant RAS were performed before and 6 months after angioplasty; @entity8 , @entity121 ( @entity121 ), cortical area (CA), and medullary length (ML) were measured from the axial slices in the 14 contralateral and 14 poststenotic then revascularized kidneys. Blood pressure, @entity1011 clearance, and number of antihypertensive drugs were analyzed. RESULTS: At 6 months, the systolic blood pressure was significantly reduced (p=0.007), but the number of antihypertensive drugs and the @entity1011 clearance did not change significantly. Most morphological parameters before and after angioplasty were different in the contralateral versus poststenotic kidneys ( @entity8 , p=0.01; @entity121 , p=0.01; ML, p=0.03; CA, p=0.008). After angioplasty, there was an 11% drop in cortical @entity194 associated with a mean 4-mm increase in medullary length in the poststenotic/revascularized kidneys. The contralateral kidneys exhibited corticomedullary thinning after angioplasty. CONCLUSIONS: In @entity8 , cortical thinning could be a useful timesaving marker to assess the significance of the lesion and to evaluate associated distal lesions. The favorable blood pressure outcome supports the existence of reversible @entity2806 , particularly in the medulla. Angioplasty appears to be useful for the poststenotic kidney, according to the morphological study.
