Pregnancy and severe @entity281 in the 2013-2014 XXXX season.

@entity1 @entity281 @entity683 @entity649
OBJECTIVE: To describe the epidemiologic and clinical characteristics of critically ill pregnant and postpartum @entity1 with @entity281 reported in the 2013-2014 season. METHODS: The California Department of Public Health conducts surveillance for @entity1 with laboratory-confirmed @entity683 who die or require hospitalization in intensive care units. For this case series, we reviewed data on pregnant and postpartum (6 weeks or less from delivery) @entity1 reported in the 2013-2014 @entity683 season. RESULTS: From September 29, 2013, through May 17, 2014, 17 pregnant @entity1 with severe @entity683 were reported. The median age was 29 years (range 17-44 years). Sixteen (94%) were in the second or third trimester. Fifteen (88%) @entity1 were hospitalized, nine (53%) required mechanical ventilation, five (29%) required emergent cesarean delivery, and four (24%) died. Of 14 @entity1 with available information, only two (14%) received @entity683 vaccination during pregnancy. Seven @entity1 who tested positive by polymerase chain reaction also had rapid @entity683 diagnostic testing performed; only one (14%) had a positive rapid @entity683 diagnostic test results. Fifteen patients received antiviral treatment; four (27%) began treatment within 48 hours of symptom onset. One additional @entity1 was 36 days postpartum and required intensive care unit admission and mechanical ventilation for @entity683 -associated acute @entity649 . CONCLUSION: Influenza remains a significant cause of morbidity and mortality in pregnant and postpartum @entity1 ; in our series, a majority were not vaccinated. During the @entity683 season, pregnant @entity1 with suspected @entity683 should receive prompt empiric antiviral therapy, regardless of rapid @entity683 diagnostic test results or vaccination status. LEVEL OF EVIDENCE: : III.
