Laparoscopy has a superior diagnostic yield than percutaneous image-guided biopsy for suspected XXXX .

@entity1 @entity706
INTRODUCTION: To date, no study has compared laparoscopy (LB) to percutaneous (PB) biopsy for the diagnosis of @entity706 . The objective of this study is to compare the success rate and safety profile of laparoscopic lymph node biopsy to the percutaneous approach in @entity1 with intra-abdominal lymphadenopathy concerning for @entity706 . MATERIALS AND METHODS: We performed a multi-institution, retrospective review of @entity1 undergoing lymph node biopsy for suspected @entity706 between 2005 and 2013. Our primary outcome was adequate tissue yield between the two techniques, both for histologic diagnosis and for ancillary studies such as flow cytometry. Secondary outcomes included 30-day morbidity, 30-day readmission rates, the need for additional lymph node biopsy procedures, and length of stay. RESULTS: All 34 of the LB @entity1 had adequate specimen for histologic diagnosis compared to 92.3  % of @entity1 with a PB (p  =  0.18). Significantly more @entity1 in the LB group had sufficient tissue for ancillary studies when needed than in the PB group, 95.5 and 68.2  %, respectively (p  =  0.04). A second biopsy was pursued in 23.1  % of failed PB @entity1 , 0  % with success on second attempt. DISCUSSION: When index of suspicion is high or when biopsy is performed for @entity1 previously diagnosed with @entity706 and recurrence/transformation is suspected, LB safely and consistently provides adequate tissue for initial diagnosis and for ancillary studies. In contrast, image-guided PB may be more appropriate for @entity1 for whom ancillary studies are unlikely to add to planned treatments or when there is a high risk of complications from either general anesthesia or @entity1 comorbidities.
