XXXX : clinical picture and long-term prognosis.

@entity1 @entity644 @entity8 @entity82 @entity101 @entity1494 @entity631 @entity262 @entity177 @entity288 @entity134 @entity1985 @entity7622 @entity454
BACKGROUND: Immunoglobulin M (IgM) @entity8 is an idiopathic @entity631 with @entity7622 and diffuse IgM deposits. METHODS: We studied clinical presentation, morphological findings, and prognostic factors in 110 @entity1 with @entity8 without @entity262 . The series included both pediatric and adult @entity1 with @entity1985 ( @entity1985 ) or minor @entity1494 . RESULTS: Mean postbiopsy follow-up was 8 years. During 15 years of follow-up, 36% of @entity1 developed @entity177 and 23% reached @entity454 . In multivariate analysis, @entity101 at the time of renal biopsy was the only significant risk factor for @entity177 . Of histological parameters, @entity82 had the strongest prognostic value. @entity101 was diagnosed in 50% of @entity1 with a postbiopsy follow-up of 15 years. Twenty-nine percent of @entity1985 @entity1 had disease resistant to @entity288 , whereas 80% of @entity1 with @entity134 -sensitive disease were @entity134 dependent. Eleven @entity1 , 8 @entity1 with @entity1985 and 3 @entity1 with asymptomatic @entity644 , underwent repeated renal biopsy. In five samples, typical morphological characteristics of focal and segmental @entity631 were seen. CONCLUSION: We propose that @entity8 can be divided into two subgroups with similar renal biopsy findings, but differences in sex distribution and initial presentation.
