Adult height and XXXX mortality in Asia: the Asia Pacific Cohort Studies Collaboration.

@entity1 @entity189 @entity409 @entity5
BACKGROUND: The observation that taller @entity1 experience an increased risk of selected @entity5 is largely restricted to Caucasian cohorts. These associations may plausibly differ in Asian populations. For the first time, we make direct comparison in the same analyses of the associations between height and a series of @entity5 in Australasian (Caucasian) and Asian populations. METHODS: Analyses were based on the Asia Pacific Cohort Studies Collaboration of 506 648 study @entity1 (408 381 Asia, 98 267 Australasia) drawn from 38 population-based cohort studies. Cox proportional hazards regression was used to estimate the relationship between height and @entity5 rates. RESULTS: A total of 3 272 600 @entity1 -years of follow-up gave rise to 7497 @entity5 deaths (4415 in Asia; 3082 in Australasia). After multiple adjustments and left censoring, taller individuals experienced increased rates of @entity189 of the intestine ( @entity1 and @entity1 ); all @entity5 , @entity409 , breast, 'other' @entity5 (all @entity1 ); and @entity5 of the prostate and bladder ( @entity1 ). No consistent regional (Asia versus Australasia) or sex differences were observed. CONCLUSIONS: In the present study, taller @entity1 and @entity1 had an elevated risk of selected @entity5 . These associations did not differ appreciably between Asian and Caucasian populations.
