Expression and significance of new @entity5 suppressor gene XXXX in primary liver cancer.

@entity5 @entity157 @entity983 @entity3
OBJECTIVE: To investigate expression and significance of @entity983 gene in primary @entity157 ( @entity157 ). METHODS: Immunohistochemical peroxidase-conjugated streptavidin (SP) method was used to detect expression of @entity983 gene in 120 cases of primary @entity157 and its adjacent tissue 10 cases of normal liver tissue. The relationship between expression of @entity5 suppressor gene of @entity983 and the percentage of lymph node @entity3 of @entity157 was analyzed. RESULTS: It was shown that @entity983 gene was expressed in all 10 cases of normal liver tissues and paracancerous liver tissues. The staining was localized mainly in cytoplasm. Expression of @entity983 in 120 cases of @entity157 were as follows: 12.5% were negative, 17.5% were weak positive, and 70% were strong positive. At time of diagnosis, 33/120 (27.5%) presented lymph node @entity3 . Lymph node @entity3 were present in 80% (12 out of 15) @entity983 negative @entity157 , 57.14% (12 out of 21) @entity983 weak positive @entity157 and only 10.71% (9 out of 84) @entity983 intense positive @entity157 , (P<0.05). Therefore, @entity983 @entity5 suppressor gene malfunction seems to be involved in metastasing capacity of @entity157 . CONCLUSION: This study suggests that @entity983 gene was deleted or weakly expressed in primary @entity157 , which is probably related to its tumorigenesis.
