Striking elevation in incidence and prevalence of XXXX in a province of western Hungary between 1977-2001.

@entity1 @entity31 @entity29 @entity1960 @entity8787 @entity14 @entity30
AIM: An investigation into @entity29 and @entity14 in Veszprem Province was conducted from 1977 to 2001. METHODS: Both hospital and outpatient records were collected and reviewed comprehensively. The majority of @entity1 were followed up regularly. RESULTS: The population of the province was decreased from 386,000 to 376,000 during the period. Five hundred sixty new cases of @entity31 ( @entity31 ), 212 of @entity30 ( @entity30 ), and 40 of indeterminate @entity1960 (IC) were diagnosed. The incidence rates increased from 1.66 to 11.01 cases per 100,000 @entity1 for @entity31 , from 0.41 to 4.68 for @entity30 and from 0.26 to 0.74 for IC. The prevalence rate at the end of 2001 was 142.6 for @entity31 and 52.9 cases per 100,000 @entity1 for @entity30 . The peak onset age in @entity31 @entity1 was between 30 and 40 years, in @entity30 between 20 and 30 years. A family history of @entity8787 was present in 3.4 % in @entity31 and 9.9 % in @entity30 @entity1 . Smoking increased the risk for @entity30 (OR=1.98) while it decreased the risk for @entity31 (OR=0.25). Twelve @entity14 were observed in this cohort, the cumulative @entity14 risk after 10 years in @entity31 was 2%, after 20 years 8.8%, after 30 years 13.3%. CONCLUSION: The incidence and prevalence rates of @entity8787 have increased steadily in Veszprem Province, now equivalent to that in Western European countries. Rapid increase in incidence rates supports a probable role for environmental factors. The rate of @entity14 in @entity8787 is similar to that observed in Western countries.
