XXXX confined to the lung is effectively treated with pulmonary metastasectomy.

@entity1 @entity358 @entity160 @entity3 @entity99 @entity4177
BACKGROUND: In @entity1 diagnosed with @entity4177 ( @entity4177 ), the lungs are the most common site of @entity3 at both initial presentation and relapse. Previous studies have encouraged pulmonary metastasectomy to achieve a disease-free state after resection of the primary @entity99 . However, there is no consensus about how to manage recurrent @entity358 . PROCEDURE: A retrospective, multi-institutional review was performed from 2005 to 2014 to identify @entity4177 @entity1  <=18years of age who had disease recurrence associated with pulmonary metastases alone. RESULTS: Ten @entity1 between the ages of 8 and 33months were identified. Pulmonary metastatic recurrence was detected by measuring @entity160 ( @entity160 ) levels and/or with CT scans of the chest. All @entity1 subsequently underwent pulmonary metastasectomy without post-operative complications. At last follow-up, 8 @entity1 were alive and had normal @entity160 levels. The 8 survivors had a median follow-up from therapy completion of 18.5months. Two @entity1 who presented with extrapulmonary recurrence subsequently died of treatment refractory disease. CONCLUSIONS: This review supports surgical resection as a safe and, in the context of multimodal therapy, efficacious approach to manage @entity4177 @entity1 who present with isolated pulmonary relapse.
