XXXX in Finland in 1981-2000: risk of dialysis-dependent @entity8 .

@entity1 @entity8 @entity177 @entity2883 @entity1011 @entity454
OBJECTIVE: To determine the risk of @entity177 requiring transient or chronic dialysis and its contributing factors in @entity1 diagnosed with @entity2883 ( @entity2883 ) between 1981 and 2000 in Finland. @entity1 AND METHODS: A retrospective cohort study using hospital discharge registers with a review of hospital case reports. Data were complemented with files from the Finnish Registry for @entity8 . All files were reviewed by 8 October 2005. RESULTS: A total of 492 @entity1 received a verified diagnosis of @entity2883 in 1981-2000. Of these, 84 (17%) needed dialysis by the end of follow-up. Of the 84 dialysed @entity1 , 32 (38%) recovered initially, 32 (38%) needed chronic dialysis (dialysed > 3 months), and 19 (23%) received a kidney transplant. Forty-one (49%) of the dialysed @entity1 were alive at the end of follow-up: 16 with a kidney transplant, 14 on dialysis, and 11 without dialysis. The cumulative rate of developing renal involvement leading to dialysis was 14.6% [95% confidence interval (CI) 11.6-18.2] at 5 years and 29.6% (95% CI 21.5-40.0) at 20 years after onset of @entity2883 symptoms. Elevated @entity1011 levels at presentation were associated with an increased rate of @entity177 requiring chronic dialysis. Age, gender, and involvement of any particular organ system had no significant effect. CONCLUSIONS: @entity2883 @entity1 are at great risk of developing @entity177 , and this risk increases as the disease progresses. Elevated @entity1011 levels at presentation are associated with an increased risk of dialysis-dependent @entity454 .
