mRNA profile of Nellore @entity291 after XXXX with Haemonchus placei.

@entity23645 @entity12524 @entity23646 @entity17299 @entity18194 @entity281 @entity7040 @entity8621 @entity291 @entity34199
Haemonchus parasites are responsible for many losses in animal production. However, few studies are available, especially of @entity7040 . In this study, we investigated mRNA differences of immune response genes in na  ve Nellore @entity291 infected with Haemonchus placei, relating these differences to patterns of cellular infiltrate. @entity291 were @entity281 . placei L3 larvae and after 7 days lymph node and abomasum tissues were collected. @entity8621 , @entity18194 , @entity12524 , IL-12, @entity23645 , IFN-y, @entity23646 , @entity34199 , pepsinogen and @entity17299 genes were evaluated by qPCR. Mast cells, eosinophils and globular leukocytes were counted by abomasum histology. In the infected group, @entity18194 , @entity23645 and @entity17299 were up-regulated in the abomasal lymph node. In the abomasum, @entity23645 increased and @entity17299 was down-regulated (p<0.05). No differences were detected for mast cells and eosinophil counts in abomasal tissue (p>0.05). We conclude that for this infection time, there was Th2 polarization but that cellular infiltrate in abomasal tissue takes longer to develop.
