Changes in XXXX resection rates.

@entity1 @entity788 @entity5 @entity1820 @entity356
BACKGROUND: Many developments in medicine are likely to have influenced the treatment of @entity1820 , including rates of resection. This study sought to investigate changes in surgical resection rates over time among @entity1 with @entity1820 . METHODS: @entity1 diagnosed between 1995 and 2012 in the Eindhoven Cancer Registry area were included. Multivariable logistic regression analysis was used to determine the independent influence of interval of diagnosis on the likelihood of having a resection. RESULTS: Among 43   370 @entity1 , crude resection rates decreased between 1995 and 2012 for @entity356 , most notably for @entity1 aged at least 85 years with @entity356 (from 37  3 to 13  3 per cent), and @entity1 aged 75-84 years and 85 years or more with @entity5 (from 80  5 to 64  4 per cent, and from 58  9 to 36  0 per cent respectively). After adjustment for @entity1 and @entity5 characteristics, @entity1 diagnosed between 2008 and 2012 with gastric (odds ratio (OR) 0  71, 95 per cent c.i. 0  55 to 0  92), colonic (OR 0  52, 0  44 to 0  62), rectal (OR 0  39, 0  33 to 0  48) and periampullary (OR 0  42, 0  27 to 0  66) @entity5 were less likely to undergo resection than those diagnosed between 1995 and 1998. @entity1 diagnosed with @entity788 were more likely to undergo resection in recent periods (OR 4  13, 2  57 to 6  64). CONCLUSION: Resection rates have fallen over time for several @entity1820 . This might reflect increased availability of other treatments, better selection of @entity1 as a result of improved diagnostic accuracy, risk-avoiding behaviour and transparency related to surgical outcomes at hospital and surgeon level.
