@entity854 and risk of developing @entity299 in XXXX .

@entity1 @entity1165 @entity713 @entity854 @entity9054 @entity299 @entity370 @entity204
BACKGROUND: Cardiac involvement is a leading cause of @entity204 from @entity370 . Because the efficacy of corticosteroid treatment is limited in @entity1 with cardiac manifestation, early diagnosis is important. However, cardiac involvement is difficult to identify at early stages and is often underdiagnosed. Therefore, this study aimed to identify electrocardiographic risk factors for @entity299 in @entity1 with @entity370 . METHODS: This prospective observational cohort study included 227 @entity1 with @entity370 who did not have any cardiac manifestation (age, 49  17years; @entity1 , 63%). We studied the association of @entity854 with developing cardiac manifestations. RESULTS: During a follow-up of 6.3  3.7years, 11 @entity1 developed @entity299 , including advanced @entity713 (4 @entity1 ), @entity1165 (4 @entity1 ), and @entity299 (3 @entity1 ). All @entity1 had @entity854 prior to the development of @entity299 . In multivariate analyses, the baseline heart rate and PR interval were associated with increased risk of developing @entity299 . The QRS duration and corrected QT interval were not associated with cardiac manifestations. The multivariate analyses also revealed that baseline @entity9054 , ST segment/T wave abnormalities, and fragmented QRS complexes were associated with @entity299 . CONCLUSIONS: @entity854 occurred prior to @entity299 in @entity370 . @entity1 with @entity854 may require further evaluation for cardiac involvement and careful follow-up.
