Predictors of nonresponse to psychosocial treatment in XXXX and adolescents with @entity952 .

@entity1 @entity146 @entity1316 @entity161 @entity9054 @entity952
OBJECTIVE: A crucial issue in youths with @entity952 , including @entity952 and @entity9054 , is the refractoriness to treatments. A multimodal approach with individual therapy to improve social skills and self-control and family and school interventions is the best psychosocial treatment. Predictors of poor response to psychosocial treatment remain understudied. We aimed at exploring whether callous (lack of empathy and guilt) and unemotional (shallow emotions) (CU) trait and type of @entity146 (predatory vs. affective) can affect response to psychosocial treatment in referred youths with @entity952 . METHODS: The sample consisted of 38 youths (28 @entity1 and 10 @entity1 , age range: 6-14 years, mean age: 13.1        2.6 years) diagnosed as having @entity952 or @entity9054 according to Diagnostic and Statistical Manual of @entity146 , 4th edition (DSM-IV) criteria and a clinical interview (Kiddie Schedule for @entity1316 and @entity161 for School-Age @entity1 -Present and Lifetime Version), who completed a 6-month therapeutic program at our hospital. @entity1 were assessed according to severity and improvement (Clinical Global Impressions-Severity score [CGI-S] and CGI-Improvement score), functional impairment ( @entity1 's Global Assessment Scale [C-GAS]), type of @entity146 , predatory versus affective (Aggression Questionnaire), and CU dimension (Antisocial Process Screening Device and the Inventory of CU Traits). RESULTS: Among the 38 @entity1 , 21 (55.3%) were responders and 17 (44.7%) were nonresponders, according to CGI-Improvement score and CGI-S. Nonresponders were more impaired at the baseline according to CGI-S and C-GAS. Nonresponders presented higher scores of predatory @entity146 , whereas affective @entity146 did not differ between groups. Nonresponders presented higher scores in CU trait of Antisocial Process Screening Device and in Inventory of CU total score (callous trait), but these differences did not survive Bonferroni correction. CONCLUSIONS: Severity at the baseline and predatory @entity146 are negative predictors of psychosocial treatment, but the role of the callous trait needs more exploration in larger samples. Further research may increase our diagnostic and prognostic capacities, thus improving our treatment strategies.
