Quantitative trait loci with sex-specific effects for internal organs weights and hematocrit value in a XXXX .

@entity944 @entity843 @entity120 @entity1573 @entity71933 @entity655 @entity209 @entity71932
UNASSIGNED: Rapid growth in broilers is associated with susceptibility to @entity209 such as @entity120 ( @entity843 ) and @entity944 . This study describes a genome search for QTL associated with relative weight of cardio respiratory and metabolically important organs (heart, lungs, liver and gizzard), and hematocrit value in a Brazilian @entity655 . QTL with similar or different effects across sexes were investigated. At 42  days of age after fasted for 6  h, the F2 @entity1573 were weighed and slaughtered. Weights and percentages of the weight relative to BW42 of gizzard, heart, lungs, liver and hematocrit were used in the QTL search. Parental, F1 and F2 individuals were genotyped with 128 genetic markers (127 microsatellites and 1 SNP) covering 22 linkage groups. QTL mapping analyses were carried out using mixed models. A total of 11 genome-wide significant QTL and five suggestive linkages were mapped. Thus, genome-wide significant QTL with similar effects across sexes were mapped to @entity71932 , 4 and 14 for heart weight, and to @entity71932 , 8 and 12 for gizzard %. Additionally, five genome-wide significant QTL with different effects across sexes were mapped to GGA 8, 19 and 26 for heart weight; GGA26 for heart % and @entity71933 for hematocrit value. Five QTL were detected in chromosomal regions where QTL for similar traits were previously mapped in other F2 @entity1573 populations. Seven novel genome-wide significant QTL are reported here, and 21 positional candidate genes in QTL regions were identified.
