Shifting incidence of solitary XXXX in the era of @entity3 . A multi-institutional study.

@entity1 @entity459 @entity1373 @entity8611 @entity3 @entity3243 @entity652
BACKGROUND: Previously, when a conventional neck exploration (CNE) without preceding diagnostic imaging was the surgical treatment for @entity1 with @entity459 ( @entity459 ) solitary @entity652 were observed in 69-88% of @entity1 . The advent of @entity3 ( @entity3 ), aiming at a preoperatively identified @entity8611 may be associated with a different incidence of solitary and multiglandular @entity8611 . MATERIALS AND METHODS: In a cohort of 467 @entity1 with sporadic @entity459 who preferentially underwent @entity3 in four hospitals in the same geographical region, the incidence of solitary @entity652 , multiple @entity652 , and @entity1373 ( @entity1373 ) was evaluated. RESULTS: A total of 367 @entity1 were scheduled for @entity3 ; 100 @entity1 underwent a planned CNE. The overall surgical success rate of the first operation was 93%, and the cumulative success rate, including a second operative procedure, was 99%. Normocalcemia resulted from removing 1 abnormal PG in 426 @entity1 (91%) and more than one abnormal gland in 35 @entity1 (8%). A @entity3243 was diagnosed in four of the 426 @entity1 with a single abnormal gland. @entity1373 was observed in 1 @entity1 . In hospitals where diagnostic workup usually consisted of ultrasound (US) and computed tomography (CT) the incidence of solitary @entity652 was 88%, compared with 96% in hospitals where MIBI, US, and CT were used preoperatively (P  =  0.007). CONCLUSIONS: A higher frequency of solitary @entity652 was observed than historically reported. The extent of the preoperative workup influences the number of observed solitary @entity652 .
