XXXX recurrence in @entity1 receiving epidural and paravertebral anesthesia: a retrospective, case-control study.

@entity1 @entity1782 @entity0 @entity5 @entity7273 @entity1722
PURPOSE: Studies have suggested an association between the use of regional paravertebral or epidural anesthesia and a reduction in @entity5 recurrence following @entity0 surgery. To examine this relationship we performed a retrospective case-control study of @entity1 undergoing @entity0 surgery receiving regional, regional and general, or general anesthesia. METHODS: A retrospective chart review was performed of @entity1 undergoing surgery for stage 0 to III @entity0 . @entity1 identified as receiving regional anesthesia were then matched for age, stage, @entity1782 ( @entity1782 ) status, @entity7273 status, and @entity1722 expression with @entity1 who received no regional anesthesia. Univariate (Pearson's   2 test and odds ratio) and multivariate logistic analyses with backward stepwise regression were performed to determine factors associated with @entity5 recurrence. RESULTS: Between 1998 and 2007, 816 @entity1 underwent surgery for stage 0-III @entity0 at our institution. Forty-five @entity1 developed @entity5 . Univariate analysis showed the use of regional anesthesia trended towards reduced @entity5 recurrence, but it did not achieve statistical significance (p = 0.06). Higher recurrence rates were associated with @entity1782 positive status (p = 0.003) and higher @entity5 stage (p < 0.0001). Age and @entity1722 status were not associated with increased @entity5 recurrence (both p > 0.11). Multivariate analysis confirmed @entity1782 status and stage as independently influential (p = 0.002 and p < 0.0001 respectively). CONCLUSION: Although we found a trend towards reduced @entity0 recurrence with the use of regional anesthesia, univariate analysis did not reach statistical significance.
