Characteristics of Left Atrial Deformation Parameters and Their Prognostic Impact in @entity1 with Pathological XXXX : Analysis by Speckle Tracking Echocardiography.

@entity1 @entity712 @entity101 @entity1184 @entity19359 @entity4346 @entity955 @entity299 @entity1121 @entity204
BACKGROUND: The pathological process of left ventricular (LV) @entity1184 is associated with left atrial (LA) remodeling. This study was aimed to evaluate the prognostic value of LA strain parameters in @entity1 with pathological @entity4346 . METHODS: This study included 95 @entity1 with @entity101 ( @entity19359 : n  =  24), @entity1121 (HCM: n  =  56), @entity299 (CA: n  =  15), and control subjects (n  =  20). We used two-dimensional speckle tracking echocardiography (STE) to analyze LA global strain. LA electromechanical conduction time (EMT) at the septal (EMT-septal) and lateral wall (EMT-lateral), and their time difference (EMT-diff) were calculated. The incidence of @entity204 and @entity712 hospitalization was defined as major @entity299 and that of @entity955 as secondary outcome. RESULTS: Left atrial volume index was increased and LA booster strain was decreased in the HCM and CA groups compared with the @entity19359 group. EMT-lateral was increased in the diseased groups compared with the control. EMT-diff was prolonged in the CA group compared with the HCM group. During the follow-up period (mean 3.4  years), major @entity299 and @entity955 occurred in 17 and 13 @entity1 , respectively. The occurrence of @entity955 was associated with CA etiology, E/e', LA volume index, LAa, and EMT-lateral. The incidence of major @entity299 was independently correlated with LA volume index and EMT-diff in multivariate analysis. CONCLUSION: This study suggested that the EMT-diff could discriminate @entity1 with a high risk of @entity299 among @entity1 with pathological @entity4346 .
