Selective Use of XXXX -Positron Emission Tomography and Computed Tomography in the Management of Metastatic Disease from @entity14 : Results from a regional centre.

@entity1 @entity419 @entity14
OBJECTIVES: Computed tomography (CT) scans are routinely used for primary staging and disease surveillance in @entity1 with @entity14 . However, these scans have limited sensitivity in some organs and can only detect lesions with morphological changes, whereas @entity419 -positron emission tomography ( @entity419 -PET) scans are able to detect areas of metabolic change before morphological changes appear. The aim of this study was to evaluate the impact of @entity419 -PET/CT scans over conventional imaging during preoperative work-ups or follow-ups in a selected group of @entity1 . METHODS: This retrospective cohort study, which took place between July 2009 and May 2011, assessed 1,043 @entity1 records from the South East Scotland Cancer Network @entity14 database. A total of 102 @entity1 who underwent @entity419 -PET/CT scans in addition to conventional imaging were included in the study. These @entity1 had potentially resectable metastases, equivocal findings on CT scans and elevated carcinoembryonic antigen levels with negative conventional imaging. RESULTS: Of the 102 @entity1 included in the study, 22 underwent a preoperative @entity419 -PET/CT scan and 80 underwent a follow-up @entity419 -PET/CT scan. In the preoperative scan group, the @entity419 -PET/CT scan had a major impact on 16 @entity1 (72.75%) and no impact on six @entity1 (27.25%). In the follow-up scan group, the @entity419 -PET/CT scan had a major impact on 51 (63.75%), a minor impact on four (5%), no impact on 22 (27.5%) and a negative impact on three (3.75%) @entity1 . CONCLUSION: The results of this study demonstrated that @entity419 -PET/CT scans have a considerable effect on disease management when undertaken among indicated @entity14 @entity1 .
