Characteristics and prognosis of XXXX : a cohort of 87 cases.

@entity1 @entity27866 @entity102 @entity9335 @entity110
BACKGROUND: As little has been published on the course of @entity110 ( @entity110 ) @entity1 cannot receive comprehensive prognostic advice. OBJECTIVE: To determine the prognosis and photobiological characteristics of idiopathic @entity110 . DESIGN: Historical cohort study, with inception cohort followed up from time of diagnosis. Follow-up for a median of 4 years (range, 3 months to 26 years) after diagnosis. SETTING: Tertiary referral center for the investigation of photodermatoses in Scotland. @entity1 : The study included 87 @entity1 , 61 (70%) of whom were female, with phototest-confirmed idiopathic @entity110 between 1975 and 2000. Sixty @entity1 (69%) were followed up clinically, and 25 @entity1 (29%) were phototested on 2 or more occasions. INTERVENTIONS: Investigations at time of diagnosis included monochromator phototesting. Further monochromator phototesting was performed in those @entity1 in whom it was clinically indicated (select subgroup), and all @entity1 who could be traced received a follow-up questionnaire. MAIN OUTCOME MEASURES: Characteristics of @entity110 , responsible wave bands, and prognosis for clinical resolution. RESULTS: The prevalence of idiopathic @entity110 in Tayside, Scotland, is estimated to be 3.1 per 100 000. Action spectra were typically broad, with 63% reacting to more than 1 wave band, and the most common provoking wavelengths were the longer UV-A and the shorter visible ones. The majority of subjects were affected perennially (68%), by radiation transmitted through glass (83%) and thin clothing (76%). Coexistent polymorphic @entity27866 occurred in 20 @entity1 (23%), and another photodermatosis occurred in 6 @entity1 , 3 of whom had chronic @entity9335 . In those with @entity110 alone, the mean age at onset was 41 years. The probability of clinical resolution at 5 and 10 years after diagnosis was 0.12 (95% confidence interval, 0.06-0.24) and 0.26 (95% confidence interval, 0.15-0.43), respectively. CONCLUSION: Idiopathic @entity110 is a @entity102 . The majority of this cohort was still affected after 5 and 10 years.
