Strategy of treatment of XXXX during pregnancy. The Drugs and Pregnancy Study Group.

@entity1 @entity40082 @entity8610 @entity5774 @entity111 @entity1245 @entity6720 @entity38206
OBJECTIVE: To present a procedure for establishing treatment guidelines during pregnancy and, as an application of the method, the recommendations for treatment of @entity111 . DESIGN: A preliminary survey was carried out among @entity1 of the study group to determine drug choices for treatment of @entity111 during pregnancy. Literature data on the selected drugs were analyzed. Recommendations for treatment were proposed, taking into account for most efficient agents and the least toxic for the fetus. This draft was submitted to all @entity1 of the study group; criticism and suggestions were gathered. A new draft was evolved and repeatedly submitted to @entity1 until consensus was reached. SETTING: Study group set up in southwestern France, with the help of national experts. @entity1 : Forty-three general practitioners, six gynecologists and/or obstetricians, five pharmacologists, two dermatologists, and an embryologist. RESULTS: The main recommendations for treatment of @entity111 during pregnancy are to begin with topical treatment; emollient bath additives, moisturizing cream, talc. If insufficient, a systemic treatment should be added. @entity8610 are prescribed first: @entity5774 or @entity38206 is used during the first 2 months. From the third month, the same agents can be used, as can @entity40082 . The duration of treatment can be up to 10 days. The group's second choice was @entity1245 ( @entity6720 ) as second-line treatment. CONCLUSIONS: Strategies for treatment of diseases during pregnancy are not always well defined. For many common diseases, very few data are available concerning drug use in pregnant @entity1 . The study group, based on consensus among @entity1 , proposed treatment guidelines.
