Comparison between a clinical activity index (Harvey-Bradshaw-Index), laboratory XXXX markers and quantitative assessment of bowel wall vascularization by contrast-enhanced ultrasound in @entity30 .

@entity1 @entity32 @entity30 @entity1851
PURPOSE: Due to its character as a remitting @entity32 , @entity1 suffering from @entity30 ( @entity30 ) often undergo several imaging studies subjecting the mostly young @entity1 to ionizing. Contrast enhanced ultrasound for capillary microvascular assessment might be a new diagnostic tool for identifying the activity of @entity32 by ultrasound techniques. MATERIALS AND METHODS: We prospectively evaluated 45 @entity1 with proven @entity30 performing contrast enhanced ultrasound (CEUS) and laboratory assessment including @entity1851 ( @entity1851 ), leucocytes and hematocrit as well as calculating the Harvey-Bradshaw Index (HBI). Thereafter, we applied the quantification software Qontrast(  ) to obtain contrast-enhanced sonographic perfusion maps. RESULTS: Analysis of the 41 finally included @entity1 revealed a correlation of @entity1851 to HBI and TTP[s], respectively. Moreover, an association was found for HBI and TTP[s] and for HBI and TTP[s]/Peak [%]. Analysis of 34 @entity1 with a Peak [%] >=  25 showed a close association of HBI and @entity1851 . Besides, in these @entity1 @entity1851 correlated to TTP[s] and to TTP[s]/Peak [%]. We found a strong negative correlation between HBI and TTP[s] (r = -0.645, p<0.01), thus, the higher the clinical activity the shorter the time-to-peak. CONCLUSION: Quantitative evaluation with CEUS, particularly the calculation of TTP[s] in @entity1 with a Peak [%] >=  25, provides a simple method to assess the inflammatory activity in @entity30 .
