Clinical outcome of open and laparoscopic surgery in Dukes' B and XXXX : experience from a regional hospital in Hong Kong.

@entity5 @entity1 @entity3
OBJECTIVE: To compare the long-term outcome of open and laparoscopic surgery for Dukes' B and @entity5 in a regional hospital in Hong Kong. DESIGN: Retrospective study. SETTING: A regional hospital in Hong Kong. MAIN OUTCOME MEASURES: Survival and local recurrence rates. @entity1 : @entity1 with Dukes' B and C @entity5 underwent elective curative open or laparoscopic surgery during the period December 2000 to December 2006. RESULTS: A total of 222 @entity1 (open surgery, n=133; laparoscopic surgery, n=89) were assessed. The overall 3- and 5-year survival rates for all @entity1 were 72% and 58%, respectively. Local recurrence rates were similar in both groups. Laparoscopic group had better overall survival (P=0.014), however. The overall 3-year survival rates were 79% and 68% in the laparoscopic and open groups, respectively. The corresponding 5-year rates were 75% and 52%. Multivariate analysis also demonstrated that laparoscopic surgery was a significant independent factor for better survival. Chemotherapy, local recurrence, lymph node @entity3 , and poorly differentiated @entity5 were significantly associated with survival. CONCLUSION: Laparoscopic surgery for Dukes' B and @entity5 was associated with more favourable survival than with open surgery.
