Renal function in newly diagnosed @entity1582 --a demographic study of 1353 XXXX . The @entity1582 Study Group.

@entity1 @entity177 @entity1582 @entity1442 @entity1011
This study describes the occurrence of @entity177 among 1353 newly diagnosed cases of @entity1582 . Renal function was evaluated by serum @entity1011 concentration in 1353 cases, 31% of whom had @entity177 at the time of diagnosis. In 1206 cases an estimation of @entity1011 clearance was made. When @entity177 was defined by using @entity1011 clearance estimation, 49% had @entity177 at the time of diagnosis. @entity177 was present in 24% of @entity1 with an M component of IgG-, 31% of IgA- and 100% of IgD-type. 52% of @entity1 with light chain disease had @entity177 . The frequency of @entity177 was similar in lambda- and kappa-light chain disease. @entity1 with a high excretion of Bence Jones protein in the urine (> 10 g/24 h) had @entity177 significantly more often than @entity1 with lower excretion. @entity177 was related to @entity1442 ; 41% of @entity1 with stage III (Durie-Salmon) disease had @entity177 . @entity177 was found in 45% of @entity1 with hypercalcaemia. When estimated @entity1011 clearance was used as a predictor of renal function, the same trends were found as mentioned above. In addition, the proportion of @entity1 with @entity177 was found to increase with advancing age.
