Spot Sign in Acute XXXX in Dynamic T1-Weighted Magnetic Resonance Imaging.

@entity1 @entity64 @entity548 @entity1410 @entity1779
BACKGROUND AND PURPOSE: In computed tomographic imaging of @entity1779 spot sign on computed tomographic angiography has been established as a marker for @entity1410 expansion and poor clinical outcome. Although, magnetic resonance imaging (MRI) can accurately visualize @entity1779 , a corresponding MRI marker is lacking to date. METHODS: We prospectively examined 50 consecutive @entity1 with @entity1779 within 24 hours of symptom onset. The MRI protocol consisted of a @entity64 protocol and dynamic contrast-enhanced T1-weighted imaging with a time resolution of 7.07 s/batch. @entity64 scores were assessed at admission and at time of discharge. Volume measurements of @entity1410 size and spot sign were performed with MRIcron. RESULTS: Contrast extravasation within sites of the @entity548 (MRI spot sign) was seen in 46% of the @entity1 . @entity1 with an MRI spot sign had a significantly shorter time to imaging than those without (P<0.001). The clinical outcome measured by the modified Rankin Scale was significantly worse in @entity1 with spot sign compared with those without (P <=0.001). @entity1410 expansion was observed in the spot sign group compared with the nonspot sign group, although the differences were not significant. CONCLUSIONS: Spot sign can be detected using MRI on postcontrast T1-weighted and dynamic T1-weighted images. It is associated with worse clinical outcome. The time course of contrast extravasation in dynamic T1 images indicates that these spots represent ongoing @entity548 .
