Metabolic status and @entity13490 in chronic XXXX over a 2-year period with continuous atypical antipsychotics.

@entity1 @entity13490 @entity1735 @entity1017 @entity161 @entity4334 @entity165
BACKGROUND: Common adverse effects of atypical antipsychotic treatments for @entity161 are @entity1017 and lipid metabolism abnormality. We aimed to identify the signs of metabolic problems with continuous atypical antipsychotic treatment for @entity161 over a 2-year period. METHODS: The @entity1 were 68 @entity161 @entity1 (29 males, 39 females; ages 53.4    13.5 years old). Changes in @entity1735 metabolism and changes in physical characteristics were studied over a 2-year period. In addition, functional single @entity4334 polymorphisms in the transcriptional regulatory region of the @entity13490 gene were examined. RESULTS: We found no changes in the mental state of the @entity1 over a 2-year period. @entity1 did show a significant decrease in total @entity165 and hemoglobin A1c levels, although physical changes such as body mass index and abdominal girth, were not observed. The amount of @entity13490 may not be associated with mental states and physical parameters. CONCLUSIONS: We could not find physical factors related to metabolic changes of antipsychotics in this 2-year study. However, several psychological factors, such as health-related thoughts and behaviors, should be studied in the future.
