XXXX : an updated experience through the last 10 years.

@entity1 @entity825 @entity162 @entity799 @entity384 @entity2177 @entity272 @entity1215 @entity4005 @entity30558
CONCLUSION: @entity30558 is a chronic, specific, granuloma of the nose and other parts of the respiratory system. The disease is endemic in Egypt and many other countries. The causative organism is @entity4005 bacillus, proved by fulfilling Koch's postulates. The mode of infection is not known and its worldwide irregular geographical distribution is not understood. Lines of treatment are unsatisfactory and a tendency for recurrence is the rule. OBJECTIVES: Our aim was to study the clinical presentation, microbiology, pathological staging, follow-up, and lines of treatment of new @entity30558 @entity1 admitted or seen at Alexandria Main University Hospital from January 1999 until January 2009. METHODS: Demographic data and the results of clinical, bacteriological, and histological examinations were reviewed. Medical and surgical treatments were evaluated. Follow-up as regards the results of treatment and incidence of recurrence was assessed. RESULTS: Fifty-six @entity1 were included in the study. There were 26 males and 30 females, and 85% of @entity1 presented in the third and fourth decades of life. The nose was affected in 100% of @entity1 . Other regions affected were the nasopharynx in 13 @entity1 , palate in 7 @entity1 , skin in 2 @entity1 , larynx in 3 @entity1 , @entity825 in 17 @entity1 , nasolacrimal duct in 2 @entity1 , and premaxilla in 1 @entity1 . No lymph node affection was reported. @entity4005 strain III was isolated from 100% of patients. Antibiotics used were a combination of @entity799 400 mg and @entity1215 300 mg twice daily for 3 months. Since 2003, this was replaced by @entity2177 500 mg twice daily for 3 months. Surgical procedures performed were removal of nasal granulations, @entity384 , @entity162 of @entity272 , tracheostomy, and repair of pharyngeal stenosis. Results were disappointing, as a large number of @entity1 did not attend for follow-up. A high incidence of recurrence was found, reaching up to 25% within 10 years.
