[Erythema and fever after XXXX i.m].

@entity1 @entity137 @entity5442 @entity3522 @entity326 @entity114 @entity733 @entity158 @entity10 @entity9156 @entity3402
We describe a @entity1 with a streptococcal @entity5442 / @entity9156 and @entity137 following an intramuscular injection with @entity3522 . A @entity1 complaining of sore throat and @entity10 for two days and fever up to 38.5 degrees C for one day consulted her family physician. 75 mg of @entity3522 were injected intramuscularly for symptomatic treatment. On the next day massive @entity158 at the injection site and a generalized erythema occurs and fever up to 38.5 degrees C persists. She is admitted to the local hospital for suspected @entity733 formation. Despite rapid antibiotic treatment a @entity326 develops. The @entity1 is transferred to a tertiary care hospital. An extensive debridement is performed and the antibiotic regimen changed to high dose @entity114 and @entity3402 . The association of life threatening diseases due to Group A streptococci and non-steroidal anti-inflammatory drugs (NSAID) is well documented by several case reports. We believe there is no longer any need for intramuscular injections of NSAID. The rare but severe complications preclude further use of the intramuscular dosage in view of the availability of oral alternatives.
