Therapeutic plasma exchange in the treatment of XXXX .

@entity1 @entity1737 @entity3935 @entity792
AIM: The aim of this study was to analyze the retrospective experience related to the indication, complication and outcome of Therapeutic Plasma Exchange (TPE) in @entity1737 ( @entity1737 ). It is a well known @entity792 characterized by antibodies against the acetylcholine receptor (anti-ACHR) on the post synaptic surface of the motor end plate. Plasma exchange is the therapeutic modality well established in @entity1737 with a positive recommendation based on strong consensus of class III evidence. MATERIALS AND METHODS: A total of 35 @entity1 of @entity1737 were submitted to a total of 41 cycles and 171 session of TPE. It was performed using a single volume plasma exchange with intermittent cell separator (Hemonetics) by Femoral or central line access and schedule preferably on alternate day interval. Immediate outcome was assessed shortly after each session and overall outcome at discharge. RESULTS: Total of 110 @entity1 of @entity1737 who were admitted to our hospital during the study period of two years. 35 (31.8%) @entity1 had TPE performed with mean age of 32 years (M:F = 2:1). The mean number of TPE session was 4.2 (SD  1.2), volume exchange was 2215 ml (SD  435); overall incidence of adverse reaction was 21.7%. All @entity1 had immediate benefits of each TPE cycle. Good acceptance of procedure was observed in 78.3% of @entity1 . CONCLUSION: TPE may be considered as one of the treatment options especially in developing countries like ours as it is relatively less costly but as effective for @entity3935 as other modalities.
