Prospective XXXX outcomes after endovascular therapy: a real-world experience.

@entity1 @entity64 @entity932 @entity5329 @entity5275 @entity583
OBJECTIVE: To report results of endovascular therapy for @entity64 ( @entity64 ) in @entity1 who were not candidates for @entity5275 ( @entity5275 ) or in whom @entity5275 failed. METHODS: Prospectively collected data for @entity1 treated between January 2006 and June 2009 were analyzed retrospectively. After careful @entity1 and therapy selection, 213 @entity64 @entity1 with a mean NIHSS score of 14.2 at presentation underwent intervention. End points analyzed were Thrombolysis in @entity583 (TIMI) 2/3 reperfusion, @entity932 ( @entity932 ) rates, and 90-day outcomes (modified Rankin Scale [mRS] and mortality). Multivariate binary logistic regression analysis was used to assess independent predictors of end points. RESULTS: Of 189 @entity1 with anterior circulation occlusions, 135 were treated within 0-8 hours, 33 were treated after 8 or more hours, and 21 were treated after @entity64 ( @entity64 ). Among 24 @entity1 treated with posterior circulation occlusions, 4 had @entity64 . After treatment, 72.3% @entity1 had TIMI 2/3 reperfusion; @entity932 rate was 8.7%; at 90 days, 36.6% recovered to @entity5329 or less. @entity932 rate was higher in @entity1 with anterior circulation @entity64 who received treatment 8 or more hours after symptom onset (odds ratio [OR] = 3.8) and @entity1 with @entity64 (OR = 4.9). In @entity1 treated within 8 hours of onset of symptoms of anterior circulation @entity64 , @entity932 rate was only 6.7%. There was no difference in outcomes in @entity1 with @entity64 compared with @entity1 treated less than 8 hours after @entity64 onset. CONCLUSIONS: This is the first and largest prospective study to the authors' knowledge that shows endovascular therapy for @entity64 @entity1 in a real-world setting. High recanalization rates with low @entity932 rates were achieved using careful @entity1 and therapy selection.
