Irradiation of @entity320 with XXXX 125 ophthalmic plaque.

@entity1496 @entity5 @entity95 @entity1953 @entity320
Radioactive @entity1496 125 is a low-energy gamma isotope with physical characteristics suitable for irradiation of @entity5 . Metal ophthalmic applicators have been designed to shield vital ocular structures while allowing irradiation of the @entity5 . We compared the radiation effects of @entity1496 125 and @entity1953 60. The Greene @entity320 was transplanted into the suprachoroidal space of @entity95 . The @entity5 then grew as an intraocular mass, was irradiated, and was followed up for two months before enucleation. Histopathologic examination defined the extent of the radiation damage to the @entity5 and other ocular structures from the @entity1496 125 and from the @entity1953 60. The eye irradiated with @entity1496 125 suffered minimal radiation damage, whereas the @entity5 was sterilized. The eye irradiated with @entity1953 60 showed substantial radiation damage, and the @entity320 was incompletely treated. Our results support the use of @entity1496 125 in treating @entity5 . More research is needed as to optimum total dose and dose rate.
