A comparative analysis of magnetic resonance imaging and high-resolution peripheral quantitative computed tomography of the hand for the detection of erosion repair in XXXX .

@entity1 @entity2681 @entity603 @entity79 @entity4421 @entity16455 @entity57410 @entity309
OBJECTIVES: To investigate whether MRI allows the detection of @entity16455 as a sign of repair of @entity79 compared with high-resolution peripheral quantitative computed tomography (HR-pQCT) as a reference and whether the presence of @entity16455 on HR-pQCT is linked to @entity603 and @entity4421 on MRI. METHODS: A total of 103 @entity309 @entity1 underwent HR-pQCT and MRI of the dominant hand. The presence and size of @entity2681 and the presence and extent (grades 0-2) of @entity16455 were assessed by both imaging modalities, focusing on @entity57410 and wrist joints. By MRI, the presence and grading of @entity4421 and @entity603 were assessed according to the @entity309 MRI Score (RAMRIS). RESULTS: Parallel evaluation was feasible by both modalities on 126 @entity79 . Signs of @entity16455 were found on 87 @entity2681 by HR-pQCT and on 22 by MRI. False-positive results (MRI(+)CT(-)) accounted for 3%, while false-negative results (MRI(-)CT(+)) accounted for 76%. MRI sensitivity for the detection of @entity16455 was 24% and specificity was 97%. The semi-quantitative scoring of @entity16455 was reliable between MRI and HR-pQCT [intraclass correlation coefficient 0.917 (95% CI 0.884, 0.941), P < 0.001]. The presence of @entity16455 on HR-pQCT showed a trend towards an inverse relationship to the occurrence and extent of @entity4421 on MRI [  (2)(1) = 3.285;    coefficient = -0.124; P = 0.070] but not to @entity603 [  (2)(1) = 0.039;    coefficient = -0.14; P = 0.844]. CONCLUSION: MRI can only rarely detect @entity16455 associated with @entity79 in @entity309 . Indeed, the sensitivity compared with HR-pQCT is limited, while the specificity is high. The presence of @entity4421 makes @entity16455 more unlikely, whereas the presence of @entity603 is not related to @entity16455 .
