Incidence of microbiological contamination of local bone autograft used in posterior lumbar interbody fusion and its association with postoperative spinal XXXX .

@entity1 @entity3256 @entity794 @entity281 @entity179
UNASSIGNED: OBJECT The aim of this study was to examine the results of microbiological cultures from local bone autografts used in posterior lumbar interbody fusion (PLIF) and to identify their association with postoperative spinal @entity281 . METHODS The authors retrospectively evaluated cases involving 328 @entity1 who had no previous spinal surgeries and underwent PLIF for @entity179 with a minimum 1-year follow-up. Local bone was obtained during laminectomy, and microbiological culture was performed immediately prior to bone grafting. The associations between culture results from local bone autografts and postoperative spinal infections were evaluated. RESULTS The contamination rate of local bone was 4.3% (14 of 328 cases). Coagulase-negative @entity794 (29%) was the most common contaminant isolated, followed by Streptococcus species and @entity3256 -sensitive @entity794 . Of 14 @entity1 with positive culture results, 5 (35.7%) had postoperative spinal infections and were treated with intravenous antibiotics for a minimum of 4 weeks. One of these 5 @entity1 also underwent reoperation for debridement during this 4-week period. Regardless of the microbiological culture results, the @entity281 rate after PLIF with local bone autograft was 2.4% (8 of 328 cases), with 5 (62.5%) of 8 @entity1 showing positive results on autograft culture. CONCLUSIONS The incidence of contamination of local bone autograft during PLIF was considerable, and positive culture results were significantly associated with postoperative spinal @entity281 . Special attention focused on the preparation of local bone for autograft and its microbiological culture will be helpful for the control of postoperative spinal @entity281 .
