[Validation of a questionnaire for the diagnosis of XXXX ].

@entity1 @entity32 @entity227 @entity16313 @entity4832 @entity70949 @entity936 @entity941 @entity3917
PURPOSE: To develop and evaluate a questionnaire for diagnosis and follow-up of @entity1 with symptoms suggestive of eye surface pathology. To evaluate the efficacy of @entity936 treatment. METHODS: Samples were chosen among @entity936 @entity1 (n=44). A control group was chosen among the healthy population. The questionnaire was filled in at the beginning and end of the treatment with @entity16313 + @entity4832 (Siccafluid, @entity70949 , Spain) four times a day. Initial and final punctuation was established and confronted with other classic diagnostic tests; @entity941 tear break up time, Schirmer test and Rose Bengal staining. RESULTS: Red eyes, lid @entity32 , discharge, @entity936 , sandy and foreign body sensations, burning, itching, discomfort, pricking, tearing and @entity3917 got significantly better after treatment (p<0.05). Lid reddening, lid @entity32 , flakes in lashes, sticky eyes in the morning, @entity227 and heavy sensation didn't improve (p>0.05). Total punctuation was significantly reduced at one month of treatment (p<0.01). Validation of the test was done against other standard tests (Schirmer test and Rose Bengal). We found a sensitivity of 76% and specificity of 71.5% for Schirmer test and a sensibility of 77% and specificity of 65% if gold standard was Rose Bengal. Predictive value (positive and negative), global value of the test and likelihood ratios were also assessed. CONCLUSION: This questionnaire is useful for diagnosis and follow-up of @entity1 with @entity936 and other ocular surface symptoms. @entity16313 + @entity4832 is useful for the treatment of @entity1 with secretor tear insufficiency.
