Assessing the @entity64 -specific quality of life for outcome measurement in XXXX rehabilitation: minimal detectable change and clinically important difference.

@entity1 @entity2045 @entity64 @entity922
BACKGROUND: This study was conducted to establish the minimal detectable change (MDC) and @entity922 ( @entity922 ) of the physical category of the @entity64 -Specific Quality of Life Scale in @entity1 with @entity64 . METHODS: MDC and @entity922 scores were calculated from the data of 74 @entity1 enrolled in randomized controlled trials investigating the effects of two rehabilitation programs in @entity1 with @entity64 . These @entity1 received treatments for 3 weeks and underwent clinical assessment before and after treatment. To obtain test-retest reliability for calculating MDC, another 25 @entity1 with @entity64 were recruited. The MDC was calculated from the standard error of measurement (SEM) to indicate a real change with 95% confidence for individual @entity1 (MDC95). Distribution-based and anchor-based methods were adopted to triangulate the ranges of minimal @entity922 . The percentage of scale width was calculated by dividing the MDC and @entity922 by the total score range of each physical category. The percentage of @entity1 exceeding MDC95 and minimal @entity922 was also reported. RESULTS: The MDC95 of the mobility, self-care, and @entity2045 ( @entity2045 ) function subscales were 5.9, 4.0, and 5.3 respectively. The minimal CID ranges for these 3 subscales were 1.5 to 2.4, 1.2 to 1.9, and 1.2 to 1.8. The percentage of @entity1 exceeding MDC95 and minimal @entity922 of the mobility, self-care, and @entity2045 function subscales were 9.5% to 28.4%, 6.8% to 28.4%, and 12.2% to 33.8%, respectively. CONCLUSIONS: The change score of an individual @entity1 has to reach 5.9, 4.0, and 5.3 on the 3 subscales to indicate a true change. The mean change scores of a group of @entity1 with @entity64 on these subscales should reach the lower bound of CID ranges of 1.5 (6.3% scale width), 1.2 (6.0% scale width), and 1.2 (6.0% scale width) to be regarded as clinically important change. This information may facilitate interpretations of @entity1 -reported outcomes after @entity64 rehabilitation. Future research is warranted to validate these findings.
