Skin tissue @entity165 (SkinTc) is related to angiographically-defined XXXX .

@entity1 @entity66 @entity453 @entity850 @entity65 @entity165
Parallel changes associated with aging found in the vasculature and skin at necropsy, have prompted small preliminary studies to assess the relation between skin tissue @entity165 (SkinTc) and @entity65 . While these studies have been suggestive, no formal investigation is available to test this association. It would, therefore, be valuable to determine whether a relation between SkinTc and angiographic narrowing actually exists, the latter representing one accepted measurement of @entity453 . METHODS: @entity1 at three hospitals undergoing coronary angiography and not on lipid altering agents (n = 649) were examined for skinTc using a non-invasive method. Vessels were evaluated manually (number with @entity850 > or = 50%). Clinical characteristics, current medication use, and Framingham global risk score were recorded. RESULTS: SkinTc was significantly higher in @entity1 with @entity66 (124 +/- 30 vs. 118 +/- 30, P = 0.02). After adjustment for traditional @entity453 risk factors, SkinTc provided 7% additional risk (per 10 SkinTc units) for @entity66 . CONCLUSION: SkinTc, measured with a non-invasive method, is associated with the presence of @entity453 as determined by catheterization. Such an assay may eventually help stratify @entity1 risk and target prevention efforts.
