The distribution of adhesion molecules in chronic XXXX .

@entity1 @entity32 @entity449 @entity4725 @entity3807 @entity4105 @entity2071 @entity1856 @entity731 @entity1028
@entity3807 is a local complication of @entity1 @entity731 . It is defined as the triad of advanced @entity731 , medical thinning and aortic adventitial @entity32 . It is present to a variable degree in association with @entity1028 . These aortic adventitial infiltrates differ from those described solely within the @entity1856 itself, in that they consist predominantly of B lymphocytes. Many of the lymphocytes are activated and proliferating, and germinal centres are common. In this study, an immunohistochemical analysis was carried out on fresh surgical @entity449 tissue in order to investigate the presence and distribution of activation-inducible adhesion molecules, and to correlate this with the degree of @entity32 . A consistent finding was the presence of @entity4105 on endothelial cells in up to 50% of the vessels throughout the aortic wall and at the base of the @entity1856 , independent of the severity of @entity32 . @entity2071 expression was abundant on many cell types and increased with the severity of @entity32 , being strongest in the germinal centres. @entity4725 expression was predominant on follicular dendritic cells and also increased with severity of @entity32 . @entity4725 expression was also detected on vessels within lymphoid follicles. The pattern of expression of the adhesion molecules suggests a role in the initiation and progression of @entity32 associated with advanced @entity731 .
