The diagnostic accuracy study of XXXX positron emission tomography/computed tomography (FDG-PET/CT), multidetector row computed tomography (MDCT) and magnetic resonance imaging (MRI) in the diagnosis of @entity45 ; a prospective single center study.

@entity8984 @entity1 @entity419 @entity2286 @entity45
UNASSIGNED: Accurate diagnosis of the nature of @entity45 is challenging but more important than ever, due partly to the increasing number of incidental cystic findings in the pancreas. Preliminary data suggest that positron emission tomography/computed tomography using @entity419 ( @entity8984 -FDG PET/CT) could have a significant influence on clinical decision making, although its role is still evolving. Our aim was to prospectively compare the accuracy of combined @entity8984 -FDG PET/contrast enhanced (ce) CT, multidetector row computed tomography (MDCT) and magnetic resonance imaging (MRI) in differentiating between malignant and benign @entity45 . METHODS: Thirty-one consecutive @entity1 with @entity45 were enrolled for the study. The @entity1 underwent a protocol including @entity8984 -FDG PET/ceCT, MDCT and MRI combined with magnetic resonance cholangiopancreatography (MRCP), all of which were evaluated blind. The findings were confirmed macroscopically at operation and/or by histopathological analysis (n = 22), or at follow-up (n = 9). RESULTS: Out of 31 @entity1 , six had malignant and 25 had benign lesions. The diagnostic accuracy of @entity8984 -FDG PET/ceCT was 94% compared with 77% and 87% for MDCT (p<0.05) and MRI, respectively. @entity8984 -FDG PET/ceCT had a NPV of 100% and a @entity2286 of 75% for @entity45 . The maximum standardized uptake value (SUVmax) was significantly higher in malignant (7.4  2.6) than in benign lesions (2.4  0.8) (p<0.05). When the SUVmax was set at 3.6, the sensitivity and specificity was 100% and 88%, respectively. Furthermore, when compared to MDCT and MRI, respectively, the clinical management of five and three @entity1 was altered after @entity8984 -FDG PET/ceCT. CONCLUSION: @entity8984 -FDG PET/ceCT is an accurate imaging modality for differentiating between benign and malignant @entity45 . We recommend the use of @entity8984 -FDG PET/ceCT in the evaluation of diagnostically challenging @entity45 .
