@entity2757 cellular distribution in normal epithelium, hyperplasia, XXXX and @entity957 and its concentration in serum.

@entity1 @entity3145 @entity75 @entity5 @entity957 @entity5072 @entity189 @entity460 @entity2757 @entity6349 @entity1141
OBJECTIVE: To investigate the function of @entity2757 , a member of the @entity460 -binding S100 protein family, in oral tumorigenesis. We analyzed its cellular distribution and its serum level in @entity1 with @entity957 and normal controls. STUDY DESIGN: We investigated the histopathologic features by @entity3145 ( @entity3145 ) including 8 normal, 66 @entity5072 and @entity6349 and 26 @entity957 ( @entity957 ) tissue cores. The serum level of @entity2757 was measured by an enzyme-linked immunosorbent assay using 33 healthy volunteers, 20 @entity1 with @entity75 and 23 @entity1 with @entity957 . RESULTS: The TMA analysis resulted in different findings. The strongest expression of @entity2757 was found in severe @entity1141 and @entity189 in situ. In @entity5 tissue an increased expression occurred only focally. In the normal tissue cores the epithelium showed a moderate reaction, but basal and parabasal cells were completely negative. The serum levels of @entity2757 were marginally reduced in @entity5 @entity1 . The expression between healthy controls and @entity1 with @entity75 displayed no difference. CONCLUSION: The expression of @entity2757 is helpful only in the transition from severe @entity6349 tissue to @entity5 .
