Quantification of lateral ventricular subdivisions in XXXX by high-resolution three-dimensional magnetic resonance imaging.

@entity1 @entity67 @entity161
In vivo brain imaging and postmortem investigations have demonstrated @entity67 in the brains of @entity161 @entity1 . However, the extent of changes in the volume of discrete ventricle subdivisions has not been clearly established. We conducted high-resolution three-dimensional magnetic resonance imaging in 40 @entity161 @entity1 (20 males and 20 females) and 40 healthy volunteers (20 males and 20 females). The lateral ventricle in each hemisphere was divided into the anterior horn, body, posterior horn and temporal horn. The volumes of the hemispheres, four subdivisions of the lateral ventricles and the third ventricle were measured. Compared to the control subjects, the bilateral hemisphere volumes were significantly lower in the @entity1 than in the control subjects. In the lateral ventricular subdivisions of the male @entity1 , the most substantial volume increase was in the left temporal horn, and volume increases were also observed in the bilateral anterior horns and the right body. The male @entity1 also had a significantly increased volume of the third ventricle. The female @entity1 showed similar patterns with less statistical significance. Thus, the @entity161 @entity1 @entity67 , particularly in the left temporal horn, being more severely affected in the male than in the female.
