Massive Endoscopic Screening for Esophageal and XXXX in a High-Risk Area of China.

@entity1 @entity5 @entity418 @entity20046 @entity356
OBJECTIVE: This study aims to describe the findings from a massive endoscopic screening program in a high-risk area of China and to evaluate the prognosis of @entity1 diagnosed through endoscopic screening compared with those diagnosed at usual hospital visits because of illness. METHODS: In 2006, an early detection and treatment program was initiated in Yangzhong county, China. Local residents aged 40-69 years were eligible for free endoscopic screening. Endoscopic examination was performed with @entity20046 staining, followed by biopsies. @entity1 diagnosed with esophageal or @entity356 were referred for treatment and followed to assess their long-term survival status. RESULTS: From 2006 through 2012, we screened 12453 @entity1 , including 5334 (42.8%) @entity1 and 7119 (57.2%) @entity1 . The average age was 52.8  8.0 years. We detected 166 @entity1 with upper digestive tract @entity5 , including 106 @entity5 in the esophagus (detection rate: 0.85%) and 60 @entity5 in the stomach (detection rate: 0.48%). Of these @entity1 , 98.11% with @entity418 and 100% with @entity356 were defined as at the early stage. In the process of follow-up, 17 @entity1 died from @entity5 -related causes, and the median survival time was greater than 85 months. The overall survival rates for 1, 3 and 5 years were 98.0%, 90.0% and 89.0%, respectively. A significant positive effect was observed for the long-term survival of @entity1 diagnosed through massive endoscopic screening. CONCLUSIONS: In a high-risk population, massive endoscopic screening can identify early stage @entity5 and improve @entity1 ' prognosis through early detection and treatment.
