XXXX as a risk factor for antipsychotic noncompliance.

@entity1 @entity1017 @entity161 @entity28
OBJECTIVE: Weight gain is a common side effect of antipsychotic medications and is of particular concern with most of the newer "atypical" antipsychotics. It is, therefore, increasingly important to understand the impact of @entity28 and perceived weight problems on compliance with these medications. METHODS: A survey of treatment and health issues was mailed to local chapters of the National Alliance for the Mentally Ill (NAMI) and National Mental Health Association (NMHA), who distributed them to @entity1 with @entity161 . Noncompliance was defined as a self-report of missing any antipsychotic medication in the previous month. The primary independent variables were (1) body mass index (BMI; weight [kg]/height [m2])-categorized as normal (< 25, n = 73), overweight (25-30, n = 104), or @entity28 (> 30, n = 100)-and (2) subjective distress over @entity1017 . Other independent variables included demographics, medication attitudes, and treatment satisfaction. RESULT: BMI status and subjective distress from @entity1017 were predictors of noncompliance. Obese individuals were more than twice as likely as those with a normal BMI to report missing their medication (OR = 2.5; CI 1.1-5.5). A comprehensive model suggested that the primary mediator of noncompliance was distress over @entity1017 . CONCLUSIONS: There appears to be a significant, positive association between @entity28 and subjective distress from @entity1017 and medication noncompliance, even when accounting for other possible confounding factors.
