Application of XXXX paste to the endotracheal tube reduces postoperative sore throat: a randomized controlled trial.

@entity1 @entity1216 @entity2995 @entity390 @entity1282 @entity5164 @entity2713
PURPOSE: This study was performed to examine whether applying @entity2995 paste as a lubricant to endotracheal tubes (ETTs) reduces the incidence and severity of postoperative sore throat (POST) more effectively than applying @entity5164 jelly. METHODS: This was a randomized controlled clinical trial. @entity1 enrolled in the study were ages 20 to 70 yr, American Society of Anesthesiologists' physical status I and II, and scheduled for elective laparoscopic cholecystectomy. The @entity1 were divided randomly into two groups, the @entity1216 group and the @entity2713 group. Prior to endotracheal intubation, ETTs in the @entity1216 group were lubricated with 0.1% @entity5164 jelly, whereas the ETTs in the @entity2713 group were lubricated with 0.1% @entity2995 paste 0.5 mg. During the 24 hr after the operation, we recorded the incidence and severity of POST and the incidence of cough, hoarseness, @entity1282 , @entity390 , and dry throat. RESULTS: Of the 150 @entity1 initially enrolled, 143 @entity1 were included in the study. The incidence of POST was significantly lower in the @entity2713 group compared with the @entity1216 group (difference = 52.4%; 95% confidence interval, 36.8% to 64.2%; P < 0.001). The severity score for the @entity2713 group was significantly lower than that for the @entity1216 group. The frequencies of coughing, hoarseness, @entity1282 , @entity390 , and dry throat were similar in the two groups for the first 24 hr after surgery. CONCLUSIONS: @entity2995 paste applied along the length of the ETT resulted in clinically important and statistically significant decreases in the incidence and severity of POST compared with the application of @entity1216 jelly. (ClinicalTrials.gov number, NCT00908817).
