Relationship of brain natriuretic peptide concentrations to left ventricular function and adverse outcomes in @entity1 with XXXX undergoing hemodialysis.

@entity1 @entity712 @entity3876 @entity740 @entity177 @entity65 @entity1002 @entity454
@entity3876 ( @entity3876 ) is a biomarker of @entity65 that is common in adults with @entity740 ( @entity740 ). However, in @entity1 with @entity740 , the range and predictive power of @entity3876 concentrations are not known. We aimed to determine the effect of HD on @entity3876 , as well as the prognostic impact of @entity3876 , in @entity454 ( @entity454 ) @entity1 undergoing hemodialysis (HD). Thirty-five @entity1 with @entity177 (16 @entity1 age 12.1    3.7 years) on maintenance HD were included. @entity3876 level was measured, and Doppler echocardiography was performed 30 min before (pre-HD @entity3876 ) and 30 min after (post-HD @entity3876 ) HD in each @entity1 . An adverse event was defined as all-cause death and @entity712 hospitalization. The median pre-HD @entity3876 , the post-HD @entity3876 , and the change in @entity3876 were, respectively, 240 pg/ml (72 to 3346), 318 pg/ml (79 to 3788), and 9 pg/ml (-442 to 1889). Pre-HD @entity3876 concentration was negatively correlated with left ventricular (LV) ejection fraction (r = -0.41, P = 0.018). During a mean follow-up of 39    14 months, 6 @entity1 died, and 3 were hospitalized for @entity712 . Using univariate analysis, @entity3876 before and after HD as well as Doppler tissue imaging velocities had a strong graded relationship with adverse events. Cox proportional hazards model demonstrated that pre-HD body weight (P = 0.008), pre-HD @entity3876 (P = 0.011), and post-HD @entity3876 (P = 0.038) remained independent predictors of adverse outcome. Even in case of @entity454 , @entity3876 still strongly correlated with @entity1002 and was associated with mortality in HD @entity1 .
