XXXX in an endemic area presenting as solitary thyroid nodules.

@entity1 @entity259 @entity189 @entity5
A retrospective analysis of 66 cases of @entity259 presenting as a solitary thyroid nodule (STN) from an endemic area is presented herein. The workup included TSH estimation and radionuclide scanning and @entity1 were divided into two groups. Group A included cases of STN @entity189 diagnosed histologically in @entity1 clinically presenting as a benign STN. Of all the @entity1 who presented with a benign STN, @entity5 was found more frequently in 'cold' nodules (13.5 per cent), than in nodules with a different presentation on scintiscanning (0-9.5 per cent). @entity5 occurred in 5 per cent of the females and in 19.5 per cent of the males. Group B included @entity1 with overt signs of @entity5 . In both groups, the clinical behaviour was determined by the stage at presentation according to TNM classification. TNM staging was found to be a good prognostic indicator, comparable to histopathology. Thus, locoregional recurrence and mortality were found to be higher in advanced T3 lesions and in Group B @entity1 . On the basis of these findings it is suggested that @entity259 may either be an earlier stage of the disease or that the @entity259 in the two groups may be separate disease entities.
