XXXX and Its Association With @entity1070 and Late Interventions After @entity439 Repair.

@entity1 @entity32 @entity1070 @entity260 @entity439 @entity1028
Importance: @entity1028 are associated with @entity32 within the aortic wall, and previous studies have suggested that @entity32 may be a consequence of a dysregulated and persistent autoimmune response. Persistent aortic remodeling after @entity439 repair could place the @entity1 at risk for endoleak or sac rupture. Objective: To determine whether @entity1 with systemic @entity32 and large @entity439 have persistent aortic remodeling after @entity439 repair (EVAR). Design, Setting, and @entity1 : The records of all @entity1 who underwent EVAR between July 2002 and June 2011 at the Veterans Affairs Connecticut Healthcare System were included in this retrospective review. @entity1 were considered to have a systemic @entity32 when confirmed by a referring specialist. Post-EVAR surveillance was performed by yearly imaging. Intervention: @entity439 repair. Main Outcomes and Measures: Significant endoleak, defined as endoleak and sac diameter increase of 0.5 cm or greater. Results: A total of 51 of 79 @entity1 (65%) had a systemic @entity32 . These @entity1 had similar comorbid conditions compared with @entity1 without @entity32 but significantly greater numbers of major @entity260 after EVAR (23.5% vs 3.6%; P   =   .02) and @entity260 after EVAR (27.5% vs 7.1%; P   =   .03). @entity1 with a history of systemic @entity32 developed more @entity1070 (45.1% vs 17.9%; P   =   .02) and late sac expansion (51.0% vs 21.4%; P   =   .01) and required more interventions (21.6% vs 3.6%; P   =   .03) during long-term follow-up. Systemic @entity32 was significantly associated with significant endoleak (odds ratio, 5.18; 95% CI, 1.56-17.16; P   =   .007). Conclusions and Relevance: @entity1 with systemic @entity32 are at high risk for @entity260 , @entity1070 , sac expansion, and additional interventions after EVAR. Additional strategies for improving the efficacy of EVAR in these @entity1 may be warranted.
