Paranasal XXXX : an 18-year single institution experience.

@entity1 @entity5 @entity2347 @entity957 @entity2802 @entity1442 @entity3 @entity5578 @entity420
OBJECTIVES: To characterize a single institution experience with management of @entity5578 during an 18-year time period, report long-term survival rates, and identify prognostic factors. STUDY DESIGN: Retrospective chart review. METHODS: Studied were 141 @entity1 treated for a @entity5578 at a single institution from 1980 to 1997 with a minimum 3-year follow-up. Gender, age, @entity2802 stage, anatomic site, pathology, treatment, and recurrence rates were reviewed. Multivariate analysis was performed to determine factors affecting survival. RESULTS: The male to female ratio was 1.6:1, and the median @entity1 age was 60 years. Most @entity1 presented with T3/T4 or locally advanced disease (88%), N0 status (96%), and M0 status (96%). The maxillary sinus was the most commonly affected site (70%), followed by the ethmoid sinus (26%). The most common @entity5 was @entity957 (51%), followed by @entity2347 (12%) and @entity420 (11%). Sixty-two percent of this study group underwent surgery as part of a multimodality curative treatment plan or alone as curative treatment. Eighteen @entity1 (13%) had unresectable local disease and received non-surgical palliative treatment. Kaplan-Meier analysis revealed the 5-year and 10-year disease-specific survival was 52% and 35%, respectively. Multivariate analysis revealed T4 stage (P =.005), N-positive stage (P =.009), and M-positive stage (P =.018) negatively impacted survival. Seventy-two @entity1 (51%) developed recurrent disease at a median time of 336 days after initial treatment. CONCLUSIONS: Most @entity1 with @entity5578 presented with locally advanced disease. @entity1442 stage, regional, and distant @entity3 are highly predictive of poor survival. Recurrence rate is high and typically occurs within the first year after treatment.
