Surgery to treat focal XXXX in adults.

@entity1 @entity410 @entity75 @entity5 @entity16490 @entity5219 @entity16 @entity51 @entity10053 @entity4940 @entity204 @entity7667 @entity4607 @entity1462
OBJECTIVE: To report clinical, neuropathological, and outcome data for a series of adult @entity1 with focal @entity4940 (fFLE) who underwent nonlobar resection restricted to the frontal lobe. METHODS: Sixty-eight adult cases (24 female and 44 male @entity1 ) were included in the study, on the basis of prospectively collected data that were retrospectively evaluated. There were 68 lesionectomies, 17 of which were combined with multiple subpial transection, with a mean follow-up period of 28.4 +/- 23.3 months. Cases involving additional extrafrontal surgery were excluded. RESULTS: Thirty-seven @entity1 underwent invasive preoperative evaluations, and 31 underwent noninvasive evaluations. Intraoperative electrocorticography was used in 32% of cases. There were 24 @entity5 , 18 @entity75 , 14 @entity75 , and 10 @entity1462 . Fifteen @entity5 were of glial origin, one was a @entity10053 , and eight were @entity7667 . The most common @entity75 were @entity4607 (15 cases). Outcomes (classified into four Engel groups) were as follows: Class I, 54%; Class II, 19%; Class III, 15%; Class IV, 12%. @entity410 -free rates were comparable for @entity5 and @entity16490 cases and were not as good for @entity1462 and @entity5219 cases. Outcome differences were not significant with respect to aura presence, side of surgery, age at the time of surgery, and age at @entity410 onset. There were 3 cases of surgical complications, 10 cases of transient @entity16 , and 1 case involving a permanent @entity51 . No @entity204 occurred. CONCLUSION: Outcomes with fFLE surgery have improved, compared with historical series. fFLE resections restricted to the frontal lobe did not yield @entity410 -free rates as good as those for comparable nonfocal @entity4940 series. All fFLE cases demonstrated histological lesions. fFLE surgery was associated with a higher risk of transient @entity51 , most likely because of the necessity for multiple subpial transection. The outcomes and higher rates of invasive evaluations and intraoperative electrocorticography indicate the special @entity4940 . The permanent @entity16 rate was low in this series, and there were no @entity204 .
