ATSDR evaluation of health effects of chemicals. V. Xylenes: health effects, toxicokinetics, XXXX exposure, and environmental fate.

@entity1 @entity11574 @entity137 @entity5600 @entity18008 @entity18683 @entity2635 @entity33935
Xylenes, or @entity11574 , are among the highest-volume chemicals in production. Common uses are for @entity18683 blending, as a solvent or component in a wide variety of products from paints to printing ink, and in the production of @entity5600 and @entity2635 . They are often encountered as a mixture of the three @entity33935 isomers, together with @entity18008 . As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that are of greatest concern for public health purposes. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of the bulk of this profile (ATSDR, 1995) into the mainstream scientific literature. An extensive listing of known @entity1 and animal health effects, organized by route, duration, and end point, is presented. Toxicological information on toxicokinetics, biomarkers, interactions, sensitive subpopulations, reducing @entity137 after exposure, and relevance to public health is also included. Environmental information encompasses physical properties, production and use, environmental fate, levels seen in the environment, analytical methods, and a listing of regulations. ATSDR, as mandated by CERCLA (or Superfund), prepares these profiles to inform and assist the public.
