Apparent diffusion coefficient: An associative factor for recurrence after nephrectomy in XXXX .

@entity5 @entity1 @entity1358
PURPOSE: To investigate whether the apparent diffusion coefficient (ADC) of a @entity5 is associated with recurrence after nephrectomy in @entity1358 ( @entity1358 ) MATERIALS AND METHODS: We retrospectively studied 49 @entity1 with localized @entity1358 who underwent 1.5T magnetic resonance imaging (MRI) including diffusion-weighted imaging preoperatively. Fifteen @entity1 had recurrent disease after surgery. The ADC was measured by placing a region-of-interest in a solid region of each @entity5 on the ADC map. We named the average value of the three ADC values the "average ADC" and the lowest ADC value among the three as the "minimum ADC." The correlations between clinicopathological factors including @entity1 age and gender, @entity5 side, @entity5 size, growth/invasion pattern, Fuhrman grade, histological subtype, venous invasion, average and minimum ADCs, and disease-free survival were analyzed by Cox proportional hazards model. RESULTS: In univariate analysis, @entity5 size, venous invasion, mean ADC, and minimum ADC showed significant correlations with disease-free survival (P < 0.05). In multivariate analysis, only venous invasion and minimum ADC were significant (P < 0.05). The 5-year disease-free survival rate of the low minimum ADC group was 51.6%, while that of the high minimum ADC group was 85.1%. CONCLUSION: The minimum ADC of a @entity5 , although not as pronounced as venous invasion, was found to be an independent associative factor for recurrence after nephrectomy in @entity1 with localized @entity1358 . J. Magn. Reson. Imaging 2015.
