[ @entity9865 (IgA-lambda type) with XXXX ].

@entity1 @entity650 @entity981 @entity295 @entity79 @entity4754 @entity9865
An 84-year-old @entity1 was admitted to Ehime University hospital because of fever and generalized swelling of lymph nodes. On admission, she did not have any @entity79 . The laboratory data included a WBC count of 60,900/microliter, with 80.5% atypical plasma cells in the peripheral blood and 26.4% in the bone marrow. The patient's serum total protein was 9.3 g/dl with increased polyclonal gamma-globulin (62.4%). Serum levels of LDH (1,986 IU/l) and @entity650 (34.3 pg/dl) were also elevated. Immunofixation-electrophoresis detected a monoclonal band defined as IgA-lambda type, with a broad band of polyclonal immunoglobulin. Southern blotting analysis demonstrated rearranged monoclonal bands in the JH and J lambda genes. Based on these findings, @entity9865 (IgA-lambda type) was diagnosed. The @entity1 was treated with combination chemotherapy for @entity981 and achieved complete remission. However, she died of @entity295 two months after admission. After chemotherapy, the patients IgG and IgM levels normalized but IgA still showed a slight increase. @entity650 also decreased, from 34.3 pg/dl to 10.2 pg/dl. To our knowledge, this report is the first in the literature concerning a case of @entity9865 with @entity4754 .
