Responses of opsonic substances to major XXXX and @entity295 .

@entity1 @entity295 @entity10287 @entity4417 @entity281 @entity130 @entity1851
Adequate opsonic capability is vital for normal host defense against @entity281 . The presence of complement fraction 3 ( @entity4417 ) indicates both classical and alternative pathways of complement activation, while complement fraction 4 ( @entity10287 ) indicates only classical pathway activation. @entity1851 ( @entity1851 ) functions as an opsonic substance. We measured serum levels of @entity4417 , @entity10287 , and @entity1851 in 32 @entity130 @entity1 . Six suffered minor @entity130 and 26 suffered major @entity130 . Nineteen of the @entity130 @entity1 developed post- @entity130 @entity295 . Complement levels fell immediately after injury and remained low for approximately 8 days in all @entity1 . @entity1851 levels rose by 12 h, peaked at 48 h, and correlated with the severity of injury and the presence of @entity295 . Elevated @entity1851 levels after 4 days postinjury indicated the presence of @entity295 in all cases. @entity1851 elevations preceded clinical diagnosis by an average of 2.4 days. Serial measurements of @entity1851 are valuable in monitoring the course of @entity130 @entity1 and may indicate the presence of septic complications before clinical detection.
