Essential XXXX and @entity2918 .

@entity1 @entity270 @entity2918 @entity1474 @entity10194 @entity35 @entity1718 @entity7322 @entity4722
The World Health Organization's recommendation for dietary intake of essential @entity1718 is 3% of energy (en%) of @entity4722 . Evidence from @entity35 studies suggests that more than 3 en% is desirable for the regulation of eicosanoid metabolism. With such a low level of available @entity4722 , @entity1 tend to synthesize more @entity2918 than they do with 6% or more energy from @entity4722 . High rates of @entity7322 probably are deleterious, so that the lower rate commensurate with 6-12 en% of @entity4722 probably is desirable. The amount of @entity4722 needed for normal function is influenced by the dietary content of other @entity1718 , particularly saturated fats and those of the n-3 family. @entity270 is necessary for normal metabolism of @entity1474 . In a diet providing sufficient available total energy with 30% as fat, the lower range of @entity4722 (6-8 en%) probably is sufficient if the @entity10194 content is 10% or less. With a greater proportion of @entity1718 , more @entity4722 is needed to maintain a polyunsaturated to @entity10194 ratio of 0.7 to 1.0. Some n-3 @entity1718 probably are required, and more than a minimal amount may be beneficial. Current recommendations are for 0.5-1.0 en% in a diet containing 5-6 en% of @entity4722 .
