Oncologic and reproductive outcome after fertility-saving surgery in XXXX .

@entity43 @entity1 @entity5 @entity600 @entity1866
The rate of @entity43 diagnosis in reproductive age @entity1 has increased parallel to the improvements in diagnostic methods and regular gynaecological visits. Because of this organ saving surgical procedures for the preservation of reproductive and endocrine functions have gained more interest. Conservative surgical approaches for @entity43 after surgical staging include cystectomy, unilateral salpingo-oophorectomy and unilateral salpingo-oophorectomy plus contralateral cystectomy. @entity43 diagnosed in young ages tend to be low-stage low-grade @entity5 . This not only enables but also necessitates preserving the fertility of @entity1 who have not completed their family. In invasive @entity43 , fertility saving surgery is confined to early-stage and low-grade disease. But, it also had been reported in advanced stages (up to Stage IIIc). Candidates for those procedures were selected according to the FIGO stage, grade, ploidy state, histological subtypes and @entity1 ' desire. Adjuvant chemotherapy is necessary for high-risk @entity1 . The rate of recurrence following conservative and radical surgical procedures in low-stage and low-grade @entity5 are 9% and 11.6%, respectively; and disease-free and overall survival rates do not differ significantly. Prognosis of borderline @entity43 is excellent. Five and 20-year survival rates are 95% and 80%, respectively. Management of borderline @entity5 has evolved significantly in the last few decades. In contrast to invasive @entity43 , borderline @entity5 can be operated on conservatively at all stages. Chemotherapy is rarely prescribed even in advanced stages. Eighty percent of malignant germ cell @entity5 are diagnosed less than 30 years of age, and 70-75% of @entity1 have Stage I disease. Conservative surgery is generally used in malignant germ cell @entity5 even in advanced stages. The relation between ovulation induction and @entity5 recurrence is not consistent in the literature. Spontaneous pregnancy rates following fertility saving surgery has been reported as 60-88%. Because of this over-treatment of these @entity1 for fertility should be avoided. Briefly, fertility saving surgery can be performed safely in germ cell, borderline and early @entity43 in selected cases. Any increment in the rate of @entity5 recurrence following ovulation induction has not yet been demonstrated. @entity1866 caused by chemotherapy are transient. The @entity600 rate of @entity43 @entity1 is slightly higher than that of the normal population, but no significant difference has been observed between @entity1 who received or did not receive chemotherapy.
