Degeneration of intrahepatic bile duct with lymphocyte infiltration into biliary epithelial cells in XXXX .

@entity1 @entity32 @entity5115 @entity2941 @entity1157 @entity2132 @entity2876 @entity99
Degenerative changes of @entity1157 with lymphocytic infiltration into portal areas have been recognized as the characteristic histopathologic features in the liver with @entity2876 ( @entity2876 ). Occasionally, lymphocytic infiltration into biliary ductal epithelium was noted and has been thought to be mostly the result of nonspecific @entity32 . However, this histological presentation looks quite similar to that of @entity2132 ( @entity2132 ) after bone marrow transplantation (BMT) or acute cellular rejection (ACR) after orthotopic liver transplantation (OLTx). According to this histological similarity, we presumed that the degeneration of @entity1157 (DIBD) might have developed with @entity5115 ( @entity5115 ) as some part of an immunologic reaction, and focused on the DIBD with @entity5115 in the @entity1 with @entity2876 . Liver specimens obtained from 31 @entity1 with @entity2876 at the time of primary Kasai operation and 3 @entity1 at the time of reoperation were reviewed histologically, and investigated DIBD with @entity5115 . Nine @entity1 with @entity2941 (CBD) and 5 @entity1 with @entity99 ( @entity99 ) were added to this study as a control population. All @entity1 with @entity2876 presented with DIBD with @entity5115 . On the other hand, only 2 @entity1 with CBD presented with DIBD with @entity5115 , and no @entity1 with @entity99 presented with DIBD with @entity5115 . The DIBD with @entity5115 is not limited to @entity1 with @entity2876 , but it seems to be much more serious in this group. These findings may suggest that some sort of immunologic factors contribute to the persistent DIBD in the @entity1 with @entity2876 .(ABSTRACT TRUNCATED AT 250 WORDS)
