Economic costs associated with moderate and late XXXX : a prospective population-based study.

@entity1 @entity204 @entity600
OBJECTIVE: We sought to determine the economic costs associated with moderate and late @entity600 . DESIGN: An economic study was nested within a prospective cohort study. SAMPLE: @entity1 born between 32(+0) and 36(+6)   weeks of gestation in the East Midlands of England. A sample of @entity1 born at >= 37  weeks of gestation acted as controls. METHODS: Data on resource use, estimated from a National Health Service (NHS) and personal social services perspective, and separately from a societal perspective, were collected between birth and 24  months corrected age (or @entity204 ), and valued in pounds sterling, at 2010-11 prices. Descriptive statistics and multivariable analyses were used to estimate the relationship between gestational age at birth and economic costs. MAIN OUTCOME MEASURES: Cumulative resource use and economic costs over the first two years of life. RESULTS: Of all eligible births, 1146 (83%) preterm and 1258 (79%) term @entity1 were recruited. Mean (standard error) total societal costs from birth to 24  months were   12  037 (  1114) and   5823 (  1232) for @entity1 born moderately preterm (32(+0) -33(+6)   weeks of gestation) and late preterm (34(+0) -36(+6)   weeks of gestation), respectively, compared with   2056 (  132) for @entity1 born at term. The mean societal cost difference between moderate and late preterm and term @entity1 was   4657 (bootstrap 95% confidence interval, 95%  CI   2513-6803; P  <  0.001). Multivariable regressions revealed that, after controlling for clinical and sociodemographic characteristics, moderate and late @entity600 increased societal costs by   7583 (  874) and   1963 (  337), respectively, compared with birth at full term. CONCLUSIONS: Moderate and late @entity600 is associated with significantly increased economic costs over the first 2  years of life. Our economic estimates can be used to inform budgetary and service planning by clinical decision-makers, and economic evaluations of interventions aimed at preventing moderate and late @entity600 or alleviating its adverse consequences. TWEETABLE ABSTRACT: Moderate and late @entity600 is associated with increased economic costs over the first 2 years of life.
