Following @entity5 prevention guidelines reduces risk of XXXX , @entity65 , and all-cause mortality.

@entity1 @entity286 @entity28 @entity5 @entity167 @entity204 @entity65
BACKGROUND: Few studies have evaluated the combined impact of following recommended lifestyle behaviors on @entity5 , @entity65 ( @entity65 ) and all-cause mortality, and most included @entity286 avoidance. Because 80% of Americans are never or former smokers, it is important to consider the impact of other recommended behaviors. METHODS: In 1992 and 1993, 111,966 nonsmoking @entity1 and @entity1 in the @entity5 Prevention Study-II Nutrition Cohort completed diet and lifestyle questionnaires. A score ranging from 0 to 8 points was computed to reflect adherence to the American @entity5 Society @entity5 prevention guidelines on body mass index, physical activity, diet, and @entity167 consumption, with 8 points representing optimal adherence. Multivariable-adjusted relative risks (RR) of @entity204 and 95% CI were computed by Cox proportional hazard regression. RESULTS: During 14 years of follow-up, 10,369 @entity1 and 6,613 @entity1 died. The RR of all-cause mortality was lower for @entity1 with high (7, 8) versus low (0-2) scores ( @entity1 , RR = 0.58, 95% CI: 0.53-0.62; @entity1 , RR = 0.58, 95% CI: 0.52-0.64). Inverse associations were found with @entity65 mortality ( @entity1 , RR = 0.52, 95% CI: 0.45-0.59; @entity1 , RR = 0.42, 95% CI: 0.35-0.51) and @entity5 mortality ( @entity1 , RR = 0.70, 95% CI: 0.61-0.80; @entity1 , RR = 0.76, 95% CI: 0.65-0.89). Similar associations, albeit not all statistically significant, were observed for never and former smokers. CONCLUSION: Adherence to @entity5 prevention guidelines for @entity28 , diet, physical activity, and @entity167 consumption is associated with lower risk of @entity204 from @entity5 , @entity65 , and all causes in nonsmokers. IMPACT: Beyond @entity286 avoidance, following other @entity5 prevention guidelines may substantially lower risk of premature mortality in older adults.
