Factors associated with outcome in 94 hospitalised foals diagnosed with XXXX .

@entity410 @entity1641 @entity75 @entity16 @entity344 @entity460 @entity551
REASONS FOR PERFORMING STUDY: @entity75 is the most common @entity16 identified in neonatal foals, but its clinical course has been rarely characterised. OBJECTIVE: To describe factors associated with non-survival in a population of foals diagnosed with @entity75 . STUDY DESIGN: Retrospective cross-sectional clinical study. METHODS: Cases were selected from @entity1641 neonatal ( <=14 days of age) admissions between 1996 and 2007. Multivariable logistic regression was used to identify clinical parameters, laboratory variables and therapeutic interventions associated with non-survival. RESULTS: A total of 94 foals were included in the study. Median age at admission was 12 h (range 0 to 96 h). The most frequently identified clinical signs included abnormal udder seeking (59%), abnormal suckle (55%), inability to stand (42%), @entity344 (37%), abnormal consciousness (34%), and @entity410 activity (22%). Overall, 75 (79.8%) foals survived to be discharged from the hospital and 19 foals died or were euthanised. Variables significantly associated with non-survival in the multivariable model were serum total @entity460 concentration, serum activity of alkaline phosphatase (ALP), recumbency, number of concurrent diseases, and use of vasopressors/inotropes. The model correctly classified 92.0% of cases. CONCLUSIONS: Overall survival was good and similar to prior reports. Vasopressors/inotropes were the only therapeutic intervention associated with non-survival, suggesting that persistent @entity551 is associated with non-survival in the current population. Foals with concurrent disease, high total @entity460 and low ALP at admission, and that were recumbent or required treatment with vasopressors/inotropes during hospitalisation were significantly less likely to survive.     This article is protected by copyright. All rights reserved.
