[ XXXX : from the desire for pregnancy to delivery].

@entity1 @entity1375 @entity249 @entity1496 @entity101 @entity548 @entity600 @entity1200 @entity1723 @entity1374
The link between @entity1375 and @entity249 is still a matter of debate. @entity1375 can result in cycle disturbances, such as @entity548 . Additionally, several studies have shown that thyroid autoimmunity (detection of anti peroxydase antibodies) may account for the occurrence of repetitive miscarriages. In @entity249 work-up, screening thyroid function should be specifically recommended for @entity1 with @entity1375 , with a personal, familial history of thyroid or other @entity1200 (such as @entity1723 ) as well as for @entity1 with unexplained @entity548 . Moreover, detection of thyroid antibody seems to be worthwhile for the assessment of recurrent miscarriages, due to the potential benefit of thyroid supplementation. In pregnant @entity1 , assessment of thyroid function seems specifically crucial to ensure adequate foetal development. Indeed, it has been well established that untreated @entity1375 may be associated with disturbances of brain development and low intellectual quotient. Additionally, other foetal (growth deficiency, @entity600 , low birth weight) as well as maternal (gestational @entity101 , pre-eclampsia...) complications have been also reported in pregnant @entity1 with @entity1375 . Consequently, screening of thyroid function should be performed in every @entity1 at risk of @entity1374 . Recent studies even advocate that thyroid screening should be extended to the overall pregnant population. The objective is to adjust L-thyroxin supplementation to maintain serum TSH concentrations below the threshold of 2.5 mUI/l. Finally, @entity1496 deficiency, currently observed in pregnant @entity1 , should be prevented by @entity1496 supply prior to conception, during pregnancy and during breast feeding as well.
