Influence of experimental XXXX on blood and myocardial @entity750 in @entity35 .

@entity296 @entity101 @entity1184 @entity1955 @entity1378 @entity4346 @entity750 @entity35 @entity65
Recent reports suggest a role for @entity750 in the pathogenesis of primary @entity101 and left ventricular (LV) @entity1184 . In this study, we have induced @entity4346 by oral feeding of @entity1955 at increasing dosages (150-450 micrograms/kg b.wt.) over a 5-week period. The effects of @entity1378 on @entity65 , blood and myocardial @entity750 concentrations were assessed. Water-fed @entity35 and formerly @entity1378 recovered animals served as controls. @entity1955 caused a significant @entity4346 : @entity1378 @entity35 2.19 +/- 0.16*; controls 1.65 +/- 0.13 g/kg b.wt. (mean +/- SD; *P less than 0.05). An almost complete regression of @entity4346 occurred in the recovery group (1.66 +/- 0.20 g/kg b.wt.) 3 weeks after cessation of thyroid hormone application. @entity1955 -treated animals showed a significant increase of @entity750 blood levels ( @entity1955 @entity35 : 2108 +/- 781*, recovery: 1132 +/- 726, controls: 705 +/- 480 ng/ml; *P less than 0.05). The concentrations of @entity750 in left ventricular myocardium were increased after thyroid hormone application, whereas the highest levels were found in the recovery group ( @entity1955 @entity35 : 139.1 +/- 30.4, recovery: 167.2 +/- 43.1, controls: 68.9 +/- 27.9 mg/ml homogenate). @entity750 -containing cells in the left ventricular myocardium were stained immunohistochemically. They were localized perivascularly and were assumed to represent tissue mast cells. In experimental @entity1378 the @entity750 levels in blood and heart are increased possibly indicating an interaction of both hormones in @entity1955 -induced @entity296 .
