Oral contraceptives and XXXX .

@entity1 @entity5892 @entity1151 @entity1150 @entity1031 @entity1186 @entity204
Recent independent studies undertaken in Britain have demonstrated s tatistically for the first time the increased risk of @entity1031 dis ease among @entity1 taking oral contraceptives. The Royal College of General Practitioners study suggests that the risk is increased about 6-fold by pregnancy and about 3-fold by oral contraceptives. The Statistical Research Unit of the M.R.C. listed 29 @entity1 with @entity1150 or @entity1151 of whom 14 had been taking oral contraceptives. Of 36 controls with other conditions only 3 were using the pill. The Committee on Safety of Drugs study reports 378 @entity204 in married @entity1 aged 15-44 during 1966; in 261 @entity1031 was mentioned on the death certificate. @entity1186 was not associated but @entity5892 and @entity1151 were possibly related to use of oral contraceptives. Deaths attributable to oral contraceptive use were approximately 3 per 100,000 users per year. In England and Wales the annual death rate for full-term pregnancies is 12 per 100,000 population. Death rate following abortions for unwanted pregnancies is higher. Advantages of oral contraceptives are, for many @entity1 , greater than the risks of iatrogenic morbidity or mortality. However, safer contraceptives must be sought as well as means of discovering which @entity1 may be at greatest risk from @entity1031 .
