Favorable outcomes in high-risk XXXX treated with multiple courses of maternal @entity5935 .

@entity1 @entity4 @entity5935 @entity358 @entity230
BACKGROUND/PURPOSE: @entity358 ( @entity358 ) are rare congenital lung lesions often diagnosed by prenatal ultrasound. High-risk cases can result in @entity4 and prenatal or postnatal demise. Antenatal @entity5935 has resulted in improved survival but it is unclear how to manage @entity1 who do not respond to a single course. METHODS: We present a bi-institutional retrospective review of @entity1 treated with multiple courses of prenatal @entity230 for high-risk @entity358 between 2007 and 2013. RESULTS: Nine @entity1 met inclusion criteria. All but one either had an increased CPAM volume ratio (CVR) or number of fluid-containing compartments involved after a single course of antenatal @entity5935 , prompting additional courses. Four @entity1 stabilized, three improved and two progressed after the second course. The two cases with disease progression underwent an in utero resection. There were one in utero fetal demise and two deaths within the delivery room. Both fetuses that underwent a fetal resection died. All but one mother who delivered a viable fetus had complications of pregnancy. CONCLUSIONS: Multiple courses of antenatal @entity5935 for high-risk fetal @entity358 often result in favorable short-term outcomes without the need for open fetal resection. Pregnancy complications are common and @entity1 within this cohort should be monitored closely.
