The neural correlates of sex differences in left-right XXXX .

@entity1 @entity1650 @entity911
Difficulties in @entity1650 ( @entity1650 ) are commonly experienced in everyday life situations. Here we investigate the neurocognitive mechanisms of @entity1650 and the specific role of left angular gyrus. Given that previous behavioral research reported @entity1 to be more susceptible to left-right @entity911 , the current study focuses particularly on the neural basis of sex differences in @entity1650 while controlling for potential menstrual cycle effects (repeated measures design). 16 @entity1 and 15 @entity1 were presented pictures of pointing hands in various orientations (rotated versus non-rotated) and were asked to identify them as left or right hands. Results revealed that @entity1650 was particularly associated with activation in inferior parietal regions, extending into the right angular gyrus. Irrespective of menstrual cycle phase, @entity1 , relative to @entity1 , recruited more prefrontal areas, suggesting higher top-down control in @entity1650 . For the subset of rotated stimuli as compared to the non-rotated, we found leftward asymmetry for both @entity1 and @entity1 , although @entity1 scored significantly lower. We conclude that there are sex differences in the neurocognitive mechanisms underlying @entity1650 . Although the angular gyrus is involved in @entity1650 , several other parietal areas are at least as critical. Moreover, the hypothesis that more left-right @entity911 is due to more bilateral activation (in @entity1 ) can be rejected.
