Hot water immersion induces an acute cytokine response in cervical XXXX .

@entity1 @entity650 @entity5733 @entity1193 @entity1566 @entity687
PURPOSE: The dysfunctional sympathetic nervous system in individuals with cervical @entity1566 (CSCI) impairs adrenergic responses and may, therefore, contribute to the blunted post-exercise cytokine response. The purpose of this study was to investigate an alternative way to exercise to induce an acute cytokine response by passive core temperature elevation in CSCI. METHODS: Seven male @entity1 with a motor complete CSCI and 8 male able-bodied controls were immersed for 60  min in water set at a temperature 2    C above the individuals' resting oesophageal temperature. Blood was collected pre, post, and every hour up to 4  h post-immersion. RESULTS: Hot water immersion resulted in an @entity650 plasma concentration mean increase of 133      144  % in both groups (P  =  0.001). On a group level, @entity650 plasma concentrations were 68      38  % higher in CSCI (P  =  0.06). In both groups, @entity687 increased by 14      11  % (P  =  0.02) and @entity1193 by 18      17  % (P  =  0.05). @entity5733 plasma concentrations were significantly reduced in CSCI (P  <  0.05) and did not increase following immersion. CONCLUSIONS: Passive elevation of core temperature acutely elevates @entity650 , @entity687 and @entity1193 in CSCI despite a blunted adrenergic response, which is in contrast to earlier exercise interventions in CSCI. The present study lays the foundation for future studies to explore water immersion as an alternative to exercise to induce an acute cytokine response in CSCI.
