Randomized trial of gastrojejunostomy with duodenal partition versus antrectomy in unresectable XXXX .

@entity1 @entity1084 @entity190 @entity5
BACKGROUND: A newly-designed gastrojejunostomy with duodenal partition was hypothesized to be a relatively easier and safer gastric bypass procedure in interrupting the "food reentry", as compared with antrectomy, for @entity1 with unresectable @entity5 . METHODS: Thirty @entity1 with unresectable periampullary malignancy were randomized to receive gastrojejunostomy with either duodenal partition or antrectomy, in addition to biliary bypass, to compare surgical risk and efficacy of the gastric bypass between these two groups. RESULTS: Gastrojejunotomy with either duodenal partition or antrectomy could significantly shorten the gastric emptying time 6 weeks after operation. There was no significant difference between these two groups in @entity1084 ( @entity1084 ) symptoms, gastric emptying time, and time for resuming oral diet intake after operation. The median operation time was shorter in the duodenal partition group (180 min) than in the antrectomy group (240 min), p < 0.01. The median @entity190 was less in the duodenal partition group (250 ml) than in the antrectomy group (400 ml), (p = 0.01). Complications occurred in 3 (20%) @entity1 with duodenal partition and in 7 (47%) @entity1 with antrectomy, (p = 0.25). One duodenal stump leakage occurred in antrectomy group. Surgical mortality occurred in 2 @entity1 with antrectomy. CONCLUSIONS: Duodenal partition, with shorter operation time and less @entity190 , had similar efficacy with antrectomy in correction of @entity1084 . Therefore, duodenal partition could be a relatively easier and safer alternative to antrectomy in interrupting the "food reentry" in gastrojejunostomy for @entity1 with unresectable @entity5 .
