Impact of Environmental Air Pollutants on Disease Control in Asmathic XXXX .

@entity748 @entity565 @entity32 @entity1
PURPOSE: Asthmatics are adversely affected by the presence of air pollutants, the concentrations of which can nowadays be measured. However, the utility of this information in clinical practice has not been defined in a group of @entity748 in stable condition. Our objective was to determine what impact the level of air pollutants had on the control of their @entity565 and the degree of @entity32 . METHODS: We performed a cross-sectional study of adult @entity748 in stable condition. From the regional environmental authority, we obtained the concentrations of ambient nitric oxide (NO2), ozone (O3), suspended particulate matter up to 10 micrometers in diameter (PM10) and sulphur dioxide (SO2) at fixed geographical points. Disease control was assessed using @entity565 control test (ACT) scores, and @entity32 using fraction of exhaled nitric oxide (FeNO) values. Correlation and linear regression studies were performed using ACT scores as the dependent variable. RESULTS: The study included 99 @entity748 , aged 39  years (SD 8), 55  % @entity1 . Mean ACT value was 17.2 (SD 6.5), and FeNO 33.7 (SD 16). Of the pollutants studied, only NO2 was correlated with ACT scores (CC  =  0.45, p  <  0.001). We found no relationship between pollutants and @entity32 . Multivariate analysis showed that ACT score was predicted by ambient air NO2 concentration and, to a lesser extent, mean FeNO. CONCLUSIONS: Information on the concentration of ambient NO2 in our environment can help the clinician to interpret the evolution of @entity748 @entity1 .
