Residual washing detergent in @entity2708 clothes: a factor of winter deterioration of dry skin in XXXX .

@entity1 @entity483 @entity2708
Although it is well known that the skin in @entity1 with @entity483 becomes drier in winter, the mechanisms of winter deterioration of dry skin are not fully understood. Our purpose was to determine whether residual washing detergent in @entity2708 clothes plays a role in the winter deterioration of atopic dry skin. We studied 148 Japanese @entity1 with @entity483 who visited our dermatology clinic during winter months. They wore @entity2708 underwear, which they had washed in cold tap water. We examined the distribution of dry skin on their trunks. We then asked them to stop washing their clothes with common anionic, additive-enriched detergents, and to use a nonionic, additive-reduced detergent for a period of two weeks. Photographs of 2 or 3 representative dry skin sites on the trunk were taken before and after the trial. By comparing the before-after trial photographs, the severity of dry skin at the end of the trial was assessed on a 5-point scale ranging from markedly improved to worsened. Of the 148 @entity1 examined, 115 (78%) had widespread or localized dry skin on the trunk. The dryness of the skin was prominent around the shoulders. Of these 115 @entity1 , 87 (76%) showed marked or moderate improvement of dry skin after the two-weeks of use of the nonionic, additive-reduced washing detergent. No @entity1 showed worsening of the dry skin. These results suggest that residues of common washing detergents in @entity2708 underclothes play an important role in the winter deterioration of dry skin in @entity1 with @entity483 who use cold tap water for washing their clothes.
