Pattern of nontyphoid XXXX over three decades in Pondicherry.

@entity1 @entity2003 @entity1680 @entity868 @entity295 @entity4628 @entity254 @entity260 @entity2737 @entity6783 @entity292 @entity158 @entity516 @entity1142 @entity221 @entity130
Two hundred and twelve cases of @entity4628 due to different causes (excluding typhoid) were treated in 3 phases in the Department of Surgery, JIPMER Hospital, Pondicherry, during the periods 1966-78 (phase I), 1981-88 (phase II) and 1990-1998 (Phase III). Forty per cent of the @entity1 were in the second and third decades of life. Male-to-female ratio was 2.2:1. The majority of the perforations (52.8%) were due to non-specific causes. @entity130 (19.3%) and mechanical factors (12.7%) were the other principal aetiologies. @entity158 abdomen (92.3%), @entity1142 (63.6%) and @entity221 (44.3%) were the principal presenting features. Abdominal guarding and @entity2003 (89%) were the main physical signs. @entity516 was present in 66.8% of cases on plain X-ray abdomen. Widal and blood culture for @entity1680 were negative in all. Laparotomy was done in most of the cases after adequate resuscitation. Simple closure of the perforation, wedge resection and resection @entity254 were the different procedures of management. Histology of the margin of perforation/excised gut gave added evidence of a non-typhoid etiology. Broad-spectrum antibiotics in different combinations with @entity868 were administered postoperatively. Mortality was 28.2% in Phase I, and 9.4% and 11.9% in phases II and III respectively. The lag period (advent of symptoms and hospitalization) showed definite relationship with mortality and morbidity. @entity2737 , wound @entity6783 , enterocutaneous @entity292 and @entity295 were the principal @entity260 .
