Optic Nerve Dysfunction in Obstructive Sleep XXXX : An Electrophysiological Study.

@entity1 @entity7286 @entity227 @entity387 @entity27 @entity520 @entity519 @entity1781 @entity25 @entity1224 @entity386
STUDY OBJECTIVES: The aim of this study was to evaluate the integrity of the visual system in @entity1 affected by @entity27 ( @entity27 ) by means of electroretinogram (ERG) and visual evoked potential (VEP). METHODS: We performed electrophysiological study of the visual system in a population of severe @entity27 ( @entity386 - @entity387 events/time in bed >=  30/h) @entity1 without medical comorbidities compared to a group of healthy controls similar for age, sex, and body mass index. @entity1 and controls did not have @entity227 with known influence on the visual system. ERG and VEP were elicited by a reversal pattern generated on a television monitor at low (55') and high (15') spatial frequencies stimulation. Daytime @entity25 was assessed using the @entity25 ( @entity25 ) in both @entity1 and controls. RESULTS: In comparison with healthy controls (n = 27), @entity1 with @entity27 (n = 27) showed a significant latency delay coupled with a significant amplitude reduction of @entity7286 wave of VEP at all spatial frequencies in both eyes. No significant differences between groups were detected as concerning ERG components. No correlations were found between polygraphic parameters, @entity25 scores, or VEP and ERG components in @entity27 @entity1 . CONCLUSIONS: This study documented that @entity1 with @entity27 , without medical comorbidities, present VEP alteration as documented by lower amplitude and longer latency of the @entity7286 component than healthy controls. These altered electrophysiological findings may be the expression of @entity1781 provoked by @entity519 , @entity520 , hypercarbia and @entity1224 , frequently observed in @entity1 with @entity27 . Hence, we hypothesize that @entity27 per se may impair optic nerve function.
