Recovery of chronic noise exposure induced @entity4207 in young male XXXX .

@entity935 @entity73 @entity4207 @entity1154 @entity750 @entity35 @entity1063
OBJECTIVE: Noise has always been an important environmental public health issue for mankind. Although reports exist on hippocampal-dependent @entity73 due to noise, there are only a few studies that have examined the effects of recovery from noise stress on @entity73 . Therefore, the present study investigated the effects of recovery from chronic noise exposure on @entity4207 . MATERIALS AND METHODS: In this study, the detrimental effects of noise stress on young male @entity35 in the Morris water maze (MWM) were investigated at 1, 10, 20, 30, and 40 days after the discontinuation of chronic noise exposure of 80 dB or 100 dB for 4 h per day, for 30 days. The levels of @entity1154 neurotransmitters in the hippocampus were also evaluated by HPLC-EC at the end of each behavioral test. RESULTS: Statistical analysis revealed that @entity35 in the noise-treated groups failed to reach the same level of performance as the controls in the MWM. Further, the levels of @entity935 (DA), @entity1063 (NE) and @entity750 ( @entity750 ) were significantly decreased in the hippocampus after noise exposure. However, the reduction in @entity1154 levels and impaired water maze performance recovered over time, so that by 30th day after cessation of noise exposure the 80 dB group showed no performance difference from the controls, and by 40th day, the 100 dB group also showed no performance difference from the control. CONCLUSION: Our findings suggest that noise impaired LM in young male @entity35 and reduced @entity1154 neurotransmitters in the hippocampus. However, the noise-induced water maze deficits recovered over time, and the concurrent restoration of hippocampal @entity1154 neurotransmitter levels suggest that they are involved in @entity73 .
