Comparing the clinical outcomes in stereotactic body radiotherapy for XXXX between Ray-Tracing and Monte-Carlo algorithms.

@entity1 @entity137 @entity5 @entity2 @entity35
PURPOSE: The purpose of this study was to compare the clinical outcomes between the groups using Ray-Tracing ( @entity35 ) and Monte-Carlo (MC) calculation algorithms for stereotactic body radiotherapy (SBRT) of @entity2 . MATERIALS AND METHODS: Thirty-five @entity1 received SBRT with CyberKnife for 47 primary or metastatic @entity2 . @entity35 was used for 22 targets in 12 @entity1 , and MC for 25 targets in 23 @entity1 . Total dose of 48 to 60 Gy was prescribed in 3 to 5 fractions on median 80% isodose line. The response rate, local control rate, and @entity137 were compared between @entity35 and MC groups. RESULTS: The response rate was lower in the @entity35 group (77.3%) compared to the MC group (100%) (p = 0.008). The response rates showed an association with the mean dose to the gross @entity5 volume, which the doses were re-calculated with MC algorithm in both groups. However, the local control rate and @entity137 did not differ between the groups. CONCLUSIONS: The clinical outcome and @entity137 of lung SBRT between the @entity35 and MC groups were similar except for the response rate when the same apparent doses were prescribed. The lower response rate in the @entity35 group, however, did not compromise the local control rates. As such, reducing the prescription dose for MC algorithm may be performed but done with caution.
