Epidemiology of XXXX in Tayside, Scotland, UK.

@entity1 @entity459 @entity2742 @entity460
OBJECTIVE: To evaluate prevalence and incidence of diagnosed @entity459 ( @entity459 ) in adults between 1997 and 2006 in Tayside, Scotland, UK. DESIGN: Population-based incidence and prevalence study. @entity1 : All Tayside residents aged 20 years and over with an increased serum @entity460 level (> 2.55 mmol/l) between 1997 and 2006 were included as potential @entity1 . Using a unique @entity1 identifier, data-linkage enabled a data set of @entity459 @entity1 to be created from an algorithm of biochemistry records, nuclear scan records, histology records, hospital clinic letters and community based prescription records. @entity1 having @entity2742 (14.0%) were also identified and were excluded. OUTCOME MEASURES: Age and sex adjusted incidence density and period prevalence were calculated for each year. RESULTS: We identified 2709 @entity1 (70.8% female) diagnosed with @entity459 by the end of 2006. The mean age of @entity1 (68 years SD = 14) was older than that of @entity1 (64 years SD = 15) at baseline. The prevalence of diagnosed @entity459 in Tayside increased from 1.82 per 1000 population in 1997 to 6.72 per 1000 population in 2006 (P < 0.001). Prevalence of @entity459 is higher in females, and the female preponderance increases with age; the annual prevalence ratio between @entity1 and @entity1 is stable at around 2.5 each year. There was a 3-4-year cyclical incidence rate varying from 4.13 to 11.30 per 10 000 @entity1 -years. CONCLUSION: We observed a general increase in the prevalence of diagnosed @entity459 in Tayside, Scotland. The incidence of diagnosis is greater in females than in males and increases with age. The annual incidence followed an apparent cyclic curve during the study period.
