[Intravoxel incoherent motion dwi in XXXX : differentiation between benign and malignant masses].

@entity1 @entity981 @entity1358 @entity359 @entity703
OBJECTIVE: To evaluate the performance of intravoxel incoherent motion (IVIM) diffusion-weighted MR imaging in the differential diagnosis of @entity359 ( @entity359 ), @entity1358 (clear cell RCC) and non- @entity1358 (non-clear cell RCC). METHOD: Forty-five @entity1 were enrolled and classified into three groups according to the surgical pathology results. There were even amount of subjects (15) in each group of @entity359 group, clear cell RCC group and non-clear cell RCC group (including 6 @entity1358 ). @entity981 the @entity1 underwent respiratory-triggered DWI on 3.0T MR system using multi b-values of 0, 20, 50, 100, 150, 200, 400, 600, 800 sec/mm(2). Pure molecular-based (D), perfusion-related (D(*)) and vascular fraction (f) were calculated using a bi-exponential model. Comparisons of derived parameters derived by IVIM-DWI among three groups were performed using One-way ANOVA. RESULTS: D in clear cell RCC (1.8    1.5) * 10(-3)mm(2)/s was significantly higher than that in @entity359 (0.7    0.3) * 10(-3)mm(2)/s or non-clear cell RCC (0.9    0.3) * 10(-3)mm(2)/s (P < 0.05), while no statistical difference was observed between @entity359 and non-clear cell RCC (P = 0.807). D(*) demonstrated significant difference between @entity359 (33.3    18.2) * 10(-3)mm(2)/s and non-clear cell RCC (17.8    17.3) * 10(-3)mm(2)/s, (P < 0.05). No observed significant difference in f was revealed between any two groups. CONCLUSION: Pure water molecules (true diffusion) and capillary microcirculation (pseudo-diffusion) may result in the observed difference of parameters in these three types of @entity703 . D value can contribute to differentiate the clear cell RCC from @entity359 , and between clear cell and non-clear cell RCC as well. D(*) value may be applied to differentiate @entity359 from non-clear cell RCC.
