Overall survival in adult @entity1 with low-grade, XXXX : Ten years' follow up at a single institution.

@entity1 @entity1313 @entity5 @entity797 @entity11 @entity1349 @entity3271
BACKGROUND: Low-grade @entity11 (LGGs) are the second most prevalent type of primary @entity1313 in adults. The prognosis for LGGs can differ according to the clinical-pathological prognostic factors determined during diagnosis and treatment. The purpose of this study was to identify 10-year, disease-free survival (DFS), 10-year @entity1349 ( @entity1349 ), and related clinical-pathological prognostic factors of adult @entity1 with supratentorial, low-grade @entity11 who were treated with or without surgery and radiation therapy. METHODS: The study included 110 @entity1 who were confirmed to have low-grade, @entity11 and who had received surgery and adjuvant radiation therapy or salvage radiotherapy as part of their treatment. These @entity1 were followed by the radiation-oncology ward at Shohada-e-Tajrish Hospital in Tehran, Iran, between 2002 and 2012. The log-rank test (univariate) and the @entity797 proportional hazards model (multivariate) were used to examine the 10-year DFS and @entity1349 and to assess the strengths of various histo-clinical factors relative to 10-year DFS and @entity1349 . RESULTS: The study included 110 @entity1 for whom 10-year DFS and @entity1349 were found to be 23 and 28%, respectively. Favorable prognostic factors in the univariate analysis using the Kaplan-Meier 10-year @entity1349 analysis were the following: age below 40, karnofsky performance status (KPS) more than 70, the presence of @entity3271 , @entity5 size of < 5 cm, and gross-total resection (p=0.02, p=0.01, p=0.03, p=0.01, p=0.02, respectively). Good prognostic factors in multivariate analysis using the @entity797 regression model were as follows: age below 40, the presence of @entity3271 , @entity5 size< 5 cm, and gross total resection in10-year @entity1349 (p=0.01, p=0.03, p=0.00, p=0.02, respectively). CONCLUSIONS: Gross-total resection, @entity5 size < 5 cm, age below 40, and the presence of @entity3271 had better 10-year DFS and @entity1349 rates. We recommend that all @entity1 with @entity5 be referred to neuro-oncology centers that have sufficient experience to achieve the best results of treatment.
