Endoscopic submucosal dissection for XXXX and noninvasive early gastrointestinal cancers.

@entity1 @entity548 @entity75 @entity5 @entity694 @entity344 @entity14 @entity674 @entity652 @entity258 @entity2909 @entity356 @entity1141
AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive @entity1 (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. @entity1 selected for ESD had @entity75 or non-invasive @entity5 of the gastrointestinal tract and had endoscopic and histological diagnoses. Early @entity5 were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 @entity652 with high grade @entity1141 , 6/39 @entity652 with @entity258 ), @entity5 (n = 7), @entity5 (n = 7) (5/7 early @entity14 , 2/7 early @entity356 ), granular cell @entity5 (n = 3), @entity674 (n = 2), and @entity2909 (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were @entity548 [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two @entity1 with @entity694 and two @entity1 with submucosal lymphatic and microvasculature invasion (1 gastric @entity5 , 1 @entity694 ) were referred to surgery. During a mean follow-up of 12 mo, 1 @entity1 with @entity652 with high grade @entity1141 underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of @entity75 and early malignant @entity344 . Successful en bloc and complete resection of lesions yield high cure rates with low recurrence.
