Adjuvant Efficacy of Nutrition Support During XXXX Treating Course: Systematic Review and Meta-analysis.

@entity1 @entity378 @entity601 @entity1907
BACKGROUND: @entity378 ( @entity378 ) tend to interact with each other. @entity378 may lead to nutrition deficiencies that will conversely delay recovery by depressing immune functions. Nutrition support can promote recovery in the subject being treated for @entity378 . The aim of this study was to evaluate the effectiveness of nutrition support on promoting the recovery of adult @entity1907 patients with anti- @entity378 drug therapy. METHODS: English database of the Cochrane Controlled Trials Register, PubMed, EMBASE, and Chinese database of CBM, CNKI, VIP, and WANFANG were searched. Randomized controlled trials comparing nutrition support (given for more than 2 weeks) with no nutrition intervention, nutrition advice only, or placebo-control for @entity378 patients being anti- @entity378 treated were included. Two reviewers conducted data extraction, assessed the quality of the studies independently, and any discrepancies were solved by the third reviewer. Data were entered and analyzed by RevMan 5.2 software, and meta-analysis was done using risk ratios (RR s) for dichotomous variables and mean differences (MDs) for continuous variables with 95% confidence intervals (CI s). RESULTS: A total of 19 studies (3681 @entity1 ) were included. In nutritional support for @entity378 @entity1 , pooled RR and its 95% CI of sputum smears- or culture-negative conversion rate and chest X-ray (CXR) absorption rate were 1.10 (1.04, 1.17) and 1.22 (1.08, 1.39), respectively, the pooled @entity601 and its 95% CI of body mass index (BMI) and time of sputum smears or culture negativity were 0.59 (0.16, 1.2) and - 5.42 (-7.93, -2.92), respectively, compared with the control group. The differences in outcomes of CXR zone affected, @entity378 score, serum albumin, and hemoglobin were not statistically significant (P = 0.76, 0.24, 0.28, and 0.20, respectively) between the intervention group and the control group. No systemic adverse events were recorded. CONCLUSIONS: During anti- @entity378 course, nutrition support may be helpful in treatment of @entity378 @entity1 by improving both sputum smears- or culture-negative conversion rate and BMI, shortening the time of sputum conversion negative. Whether it can improve the final clinical effect, there still needs high-level quality studies to confirm in the future.
