Analysis of postoperative radiation therapy in stage I through XXXX .

@entity1 @entity43 @entity2194 @entity66 @entity41 @entity29 @entity1391
A retrospective long-term analysis of the results of primary postoperative radiotherapy in 106 @entity1 with @entity43 is presented. Forty-two @entity1 received @entity2194 , and 64 received treatment by various subtotal abdominopelvic techniques. The mean follow-up of living @entity1 in the two groups is 86 and 116 months, respectively. @entity1 who had Federation International Gynecology and Oncology (FIGO) stages I through III-A with no postoperative @entity66 , or less than 0.5-cm abdominal and/or less than 2-cm pelvic @entity66 formed a favorable group in whom total abdominopelvic irradiation resulted in a 71% 10-year actuarial relapse-free survival rate compared with 40% for those treated by subtotal abdominopelvic techniques (P less than or equal to .0205). The survival improvement due to the total abdominopelvic technique in favorable @entity1 became even more significant (P less than or equal to 0.003) after adjusting for differences in stage, grade, and postoperative @entity66 volume (no, or favorable, gross). Increasing grade appeared to be associated with decreasing survival even among favorable @entity1 treated with the optimal technique, although the differences did not approach statistical significance after adjusting for @entity66 volume and stage. @entity29 were equivalent, 7.1% for total abdominopelvic v 8.1% for subtotal abdominopelvic techniques. The addition of intraperitoneal radioactive chromic @entity1391 increased the surgical bowel complication rate 33% over external pelvic irradiation alone without improving survival. @entity1 with unfavorable gross @entity66 and/or FIGO stages III-B and IV were incurable by any radiation technique. Those with no, or favorable, gross @entity41 constitute a group in whom we believe @entity2194 represents a potentially curative therapy modality.
