Surgical interventions for @entity1790 in XXXX and the general population.

@entity1 @entity1691 @entity1790 @entity1290 @entity299
OBJECTIVE: The aim of this study was to estimate rates and type of definitive surgical interventions for @entity1790 in Swedish @entity1 with @entity1691 ( @entity1691 ) compared to the general population. MATERIALS AND METHODS: This national prospective cohort study linked data from Swedish population and healthcare registries. Incidence rates and interventions for @entity1790 during follow-up in @entity1 with @entity1691 were compared to general population comparator (GPC) subjects. RESULTS: In total, 8572 @entity1691 @entity1 were followed for 49,959 @entity1 -years and 39,639 matched GPCs were followed for 225,221 @entity1 -years. Mean age at study entry was 46 years [interquartile range (IQR) 36-56 years] and 65% were male. In @entity1691 @entity1 with a diagnosis of @entity1790 during the study period, 29% (72/250) underwent similar intervention for @entity1790 compared to 24% (114/466) GPCs (p = 0.21). The incidence rate ratio (RR) in overall @entity1691 @entity1 was 2.9 [95% confidence interval (CI) 2.1-3.8] during a median follow-up of 6.2 years (IQR 3.2-8.6 years). With prior diagnosis of @entity1790 , the RR for @entity1691 @entity1 compared to GPCs was 3.7 (95% CI 1.8-7.7); without prior @entity1790 the RR was 2.1 (95% CI 1.5-3.0). Increasing age [odds ratio (OR) 1.02, 95% CI 1.01-1.03], prior @entity1790 diagnosis (OR 3.3, 95% CI 1.97-5.62) and @entity299 (OR 2.0, 95% CI 1.03-3.91) were identified as predictors of intervention for @entity1790 . CONCLUSIONS: @entity1 with @entity1691 have an almost three-fold increased risk of surgical intervention for @entity1290 , with similar management, compared to the general population.
