[Ghrelin expression in the tissues of different XXXX ].

@entity1 @entity8170 @entity1377 @entity706 @entity2743 @entity2621 @entity5 @entity189 @entity1378 @entity259 @entity14950 @entity1374
OBJECTIVE: To investigate whether ghrelin, a novel endogenous ligand of @entity14950 ( @entity14950 ), was expressed in the thyroid tissues of different @entity1374 , and its implication. METHODS: The paraffin-embedded specimens of thyroid tissues from 2000 to 2004 were obtained from 57 @entity1 with different @entity1374 , including 5 subacute @entity1374 , 8 @entity2621 , 7 @entity1378 ( @entity2743 ), 8 @entity8170 , 5 @entity259 , 3 @entity706 , 8 @entity1377 , 3 @entity189 , 5 @entity189 and 5 @entity189 cases. The specimens of normal peri-adenoma thyroid tissues served as controls. Immunohistochemical staining was used to detect ghrelin expression. RESULTS: (1) ghrelin expression was undetectable in the thyroid tissues of normal control, subacute @entity1374 , @entity2621 and @entity2743 . (2) ghrelin expression was also undetected in the tissues of @entity8170 , @entity259 and @entity706 . (3) ghrelin-positive staining was found in the @entity5 cells of different types of @entity259 . Five cases were positive within 8 cases in @entity1377 , 2 cases were positive within 3 cases in @entity189 , 3 cases were positive within 5 cases in @entity189 , 3 cases were positive within 5 cases in @entity189 . CONCLUSION: Ghrelin is expressed in @entity259 , but not in autoimmune or inflammatory @entity1374 and benign nodular @entity1374 . The results indicate that ghrelin expression may play an important role in the occurrence and development of @entity259 .
