A randomized trial comparing @entity396 three and seven days after @entity1499 for XXXX .

@entity1 @entity6003 @entity3556 @entity5852 @entity548 @entity396 @entity3009 @entity1499
OBJECTIVE: Our purpose was to determine whether vaginal @entity396 7 days rather than 3 days after @entity1499 injection increases the percent of successful abortions on the day of @entity396 administration. STUDY DESIGN: A randomized controlled trial was performed in @entity1 requesting an abortion at < or = 56 days' gestation. Eighty-six @entity1 were treated with @entity1499 50 mg/m2 intramuscularly followed 3 days (group 1) or 7 days (group 2) later by vaginal @entity396 800 micrograms. The @entity396 dose was repeated if the abortion did not occur. RESULTS: @entity5852 occurred in 38 of 46 (83%) @entity1 in group 1 and 39 of 40 (98%) in group 2 (p = 0.033). Of the @entity1 with complete abortions, 30 of 46 (65%) in group 1 and 27 of 40 (68%) in group 2 aborted the same day as the first or second dose of @entity396 (p = 0.823). @entity3556 lasted 14 +/- 5 (mean +/- SD) days in group 1 and 17 +/- 9 days in group 2. The remaining @entity1 aborted after a delay of 24 +/- 6 days in group 1 and 28 +/- 13 days in group 2. For these @entity1 vaginal @entity548 lasted 18 +/- 17 and 14 +/- 7 days, respectively, and the @entity1 chorionic gonadotropin-beta level was < or = 25 IU/L by 22 +/- 7 days after the abortion in group 1 and 19 +/- 9 days in group 2. Treatment failures in group 1 were four continuing pregnancies (9%), two @entity6003 (4%), and two @entity1 who requested surgical termination after receiving both medications (4%). The treatment failure in group 2 was an @entity6003 . @entity1499 and @entity396 side effects were infrequent. CONCLUSIONS: @entity1499 and vaginal @entity396 are more effective abortifacients when the @entity396 is given 7 days rather than 3 days after @entity1499 . This treatment regimen may offer an alternative to surgical abortion or the use of antiprogestins and @entity3009 for medical abortion.
