Spindle cell @entity957 and XXXX of the skin: a comparative study of 38 cases.

@entity1 @entity242 @entity1389 @entity5 @entity957 @entity204 @entity320
Thirty-eight cutaneous lesions previously diagnosed as spindle cell @entity957 , " @entity1389 ," or dermal @entity242 are presented. Two @entity1 had two lesions each; thus, there were 36 @entity1 . Cases of @entity320 (including @entity320 ), @entity242 of subcutaneous origin, and " @entity242 " were excluded. On review, the lesions fell into two categories: (1) those with a definite component of invasive @entity957 in addition to @entity242 -like areas (8 cases), and (2) those in which such a squamous component was not identified (30 cases). Cases in the former group were considered proven spindle cell @entity957 , while those in the latter group were designated noncommittally as @entity5 . Almost all @entity1 were white and over 40 years of age. Four @entity5 (from three @entity1 ) arose in areas previously treated with x-ray and all but two (both spindle cell @entity957 ) of the remainder in both categories arose in sun-damaged skin. Prognosis did not differ significantly between the two categories but depended primarily on the depth of invasion. Two of two @entity5 that extended into bone and four of seven that invaded skeletal muscle caused @entity204 ; all of those involving only dermis (24) or dermis and subcutis (five) were successfully extirpated. Origin in an area that had received x-ray was also an unfavorable prognostic indicator; all three @entity1 whose lesions arose in such areas died of @entity5 . This may have been related to depth of invasion because the three fatal @entity5 all invaded muscle. It was concluded that the distinction between spindle cell @entity957 and "atyical fibroxanthoma" is of little prognostic import per se, but rather that prognosis is primarily dependent on the depth of invasion and, perhaps, the type of antecedent irradiation.
