HLA and @entity2262 expression in basal and XXXX of the skin.

@entity5 @entity957 @entity2262 @entity1491
Histologic sections of seven @entity957 ( @entity957 ), 13 @entity1491 ( @entity1491 ), and a Bowenoid actinic keratoses were examined for expression of HLA class 1 antigens (HLA-ABC) using a monoclonal antibody and an immunoperoxidase technique. Expression of @entity2262 was examined with a polyclonal antibody method. Neither cell marker was detected within the Bowenoid actinic keratoses. @entity957 and @entity1491 exhibited decreased expression of both HLA-ABC and @entity2262 and often did not express these antigens at all. HLA-ABC was present in only two of 13 @entity1491 and four of seven @entity957 . @entity2262 was present in one of 13 @entity1491 and two of seven @entity957 . When present, these antigens often were present in a few areas of the @entity5 , but absent in others. In both @entity957 and @entity1491 , both antigens were usually lost simultaneously. In all @entity5 with @entity2262 , HLA-ABC also was retained. There was no apparent relationship of anatomic site or type of @entity5 with retention of surface antigens. Since some @entity5 or portions of @entity5 retained HLA-ABC and @entity2262 on their surfaces, the absence of these antigens is not an absolute marker for @entity5 .
