Modern management of XXXX : a case series and review of the literature.

@entity1 @entity5572 @entity66 @entity5990 @entity10577 @entity733 @entity99
BACKGROUND: Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional radiology, has decreased mortality rates. The aim of this study was to review our experience in managing @entity10577 , review the literature in this field, and propose guidelines to aid in the current management of this complex disease. METHODS: Demographic and clinical details of all @entity1 admitted to a single institution with @entity5572 over a 5 year period were reviewed. Clinical presentation, aetiology, diagnostic work-up, treatment, morbidity and mortality data were collated. RESULTS: Over a 5 year period 11 @entity1 presented to a single institution with @entity99 (55% males, mean age 60.3 years). Common clinical features at presentation were non-specific constitutional symptoms and signs. Aetiology was predominantly @entity5990 (45%) or @entity66 (27%). In addition to empiric antimicrobial therapy, all @entity1 underwent radiologically guided percutaneous @entity5572 at diagnosis and only 2 @entity1 required surgical intervention, including one 16-year old female who underwent hemi-hepatectomy for a complex and rare @entity733 . There were no mortalities after minimum follow-up of one year. CONCLUSIONS: @entity10577 are uncommon, and mortality has decreased over the last two decades. Antimicrobial therapy and radiological intervention form the mainstay of modern treatment. Surgical intervention should be considered for @entity1 with large, complex, septated or multiple abscesses, underlying disease or in whom percutaneous drainage has failed.
