Diagnostic value of troponin T for alterations in left ventricular mass and function in dialysis XXXX .

@entity1 @entity712 @entity10020 @entity4346 @entity299 @entity454
BACKGROUND: @entity10020 ( @entity10020 ) is related to left ventricular (LV) mass in @entity1 with @entity454 ( @entity454 ). Furthermore, @entity10020 reflects the severity of @entity299 in @entity1 with @entity299 . We tested the diagnostic value of @entity10020 for @entity4346 ( @entity4346 ) and LV @entity299 in a large group of clinically stable hemodialysis @entity1 without @entity712 . RESULTS: @entity10020 was significantly (P < 0.001) higher in @entity1 with @entity4346 than in those with normal LV mass. In a multiple logistic regression model, adjusting for potential confounders (including @entity299 ), systolic pressure and @entity10020 (both P = 0.003) were the strongest correlates of @entity4346 . Similarly, @entity10020 was significantly higher (P = 0.005) in @entity1 with @entity299 than in those with normal LV function and in a multiple logistic regression model @entity10020 ranked as the second independent correlate of this alteration after male sex. Serum @entity10020 had a high positive prediction value for the diagnosis of @entity4346 (87%) but its negative prediction value was relatively low (44%). The positive predictive value of @entity10020 for LV dysfunction was low (25%) while its negative predictive value was high (93%). A combined analysis including systolic pressure (for the diagnosis of @entity4346 ) and sex (for the diagnosis of LV @entity299 ) augmented the diagnostic estimates to an important extent (95% positive prediction value for @entity4346 and 98% negative prediction value for LV @entity299 ). CONCLUSIONS: @entity10020 has a fairly good diagnostic potential for the identification of @entity4346 and for the exclusion of LV @entity299 in @entity1 with @entity454 without @entity712 . This marker may be useful for the screening of alterations in LV mass and function in clinically stable hemodialysis @entity1 .
