Measurement of Voluntary Cough Production and Airway Protection in XXXX .

@entity1 @entity1726 @entity9666 @entity191
OBJECTIVE: To examine relationships between Peak expiratory (cough) airflow rate and swallowing symptom severity in @entity1 with @entity191 DESIGN: @entity1 were cued to cough into an analog peak flow meter then swallowed three, 20 mL thin liquid @entity9666 boluses. Analyses were directed at detecting potential relationships among disease severity, swallowing symptom severity and PEFR. @entity1 : Sixty eight male and females with @entity1726 . INTERVENTIONS: Not applicable MAIN OUTCOME MEASURES: PEFR and swallow symptom severity RESULTS: PEFR varied significantly across swallowing severity classifications. @entity1 with more severe disease displayed a significant, linear decrease in PEFR compared to those @entity1 with earlier stage, less severe disease. Swallowing symptom severity varied significantly across groups when comparing @entity1 with less severe @entity1726 to those with more severe @entity1726 . @entity1 with early-stage @entity1726 demonstrated little to no swallowing symptoms and had the highest measures of PEFR. In contrast, @entity1 with the most severe swallowing symptoms also displayed the lowest measures of PEFR. CONCLUSIONS: Relationships existed among @entity1726 severity, swallowing symptom severity and PEFR in @entity1 with @entity1726 . PEFR may eventually stand as a non-invasive predictor of aspiration risk in those with @entity1726 , particularly later-stage disease. Inclusion of PEFRs into existing clinical swallowing assessments may increase the sensitivity and predictive validity of these assessments.
