XXXX of the maxillary antrum.

@entity1 @entity2347 @entity5 @entity146
PURPOSE: To investigate characteristic clinical features and outcome for @entity1 with @entity2347 ( @entity2347 ) of the maxillary antrum. @entity1 AND METHODS: Twenty-two @entity1 with @entity2347 of the maxillary antrum were initially treated with surgery alone (3 @entity1 ), radiation alone (9 @entity1 ), or a combination of surgery and radiation (10 @entity1 ). Salvage treatment for initial failure was individualized. Patterns of failure, survival, and prognostic factors were retrospectively analyzed. RESULTS: The most frequent site of failure was local recurrence at the primary site (72.7%). All @entity1 treated with either surgery alone or radiation alone experienced one or more local recurrences, whereas @entity1 who received planned combined surgery and radiation had a much lower local recurrence rate (40%). Neck node failure (4.6%) was an uncommon event, whereas distant metastases were clinically documented in seven @entity1 (32%). Most of the treatment failures appeared within 5 years, but treatment failures after 5 years were not uncommon. The overall survival and disease-free survival rates at 10 years were 37.6% and 13.6%, respectively. Clinicopathological factors, such as location of @entity5 , @entity5 stage, and histological grade were of no value in predicting a favorable survival. The significant prognostic factors influencing 10-year survival were the pathological finding of perineural invasion and the initial mode of treatment. CONCLUSION: @entity2347 of the maxillary antrum represented a unique natural history characterized by a more @entity146 behavior and an unfavorable prognosis. Combined surgery and radiotherapy is recommended for optimal local control and survival.
