[Treatment of pelvic recurrences of XXXX by radiotherapy alone].

@entity1 @entity189 @entity2622 @entity5
The best way to treat locally recurrent @entity2622 has not been established. Our retrospective study refers to 37 consecutive @entity1 , with recurrence in the pelvis, treated by radiotherapy alone. Thirty @entity1 were treated by external beam therapy alone; intracavitary brachytherapy alone was adopted in 3 @entity1 and a combination of both techniques in 4 @entity1 . The total radiation dose exceeded 60 Gy in 62% of cases. A complete clinical response was observed in 54% of @entity1 and a partial response in 32.4%. Overall crude survival was 70.3%, 28.9% and 23.2% at 1, 3 and 5 years respectively. In @entity1 with recurrent @entity5 less than 40 mm in diameter a threefold 3-year survival was achieved (48.6% vs. 14.5%, p less than 0.025). With total doses higher than 60 Gy the 3-year survival resulted to be far better than with lower doses (39.1% vs. 10%, p less than 0.025). A significant advantage was also observed in the "complete responders" group (44% vs. 11.8%), but this difference can be explained by the link between response and the above-mentioned basic prognostic factors. Acute side effects and late complications were moderate and did not correlate with the type of primary treatment. A significant percentage (about 25%) of @entity1 with locally recurrent @entity189 may reach medium-term survival; better results can be achieved in selected groups with favourable prognostic factors and with adequate radiotherapeutic treatment.
