Personality pathology and treatment outcome in XXXX : a review.

@entity1 @entity1314 @entity308 @entity663
OBJECTIVE: A longstanding belief among many clinicians is that @entity1 with @entity308 and comorbid @entity1314 pathology have a worse response to standard @entity308 treatment. This presents potentially significant treatment implications, since @entity1314 pathology in @entity308 @entity1 appears to be common. METHOD: PsycINFO and MEDLINE were systematically searched for studies relating @entity1314 to treatment outcome. Over 50 studies were obtained and grouped according to the method used to assess @entity1314 pathology. RESULTS: High @entity663 scores generally predicted worse outcome, especially over long-term follow-up. Tridimensional Personality Questionnaire scores did not have a consistent relationship to treatment outcome despite some promising initial findings. Most studies involved @entity1 with @entity1314 ; these studies produced conflicting results. Other measures of @entity1314 pathology produced an array of findings ranging from a moderately worse outcome to no difference. CONCLUSIONS: Whether or not @entity1314 pathology significantly worsens outcome in @entity1 with @entity308 appears to depend on study design, since the rate of @entity1314 pathology varies markedly depending on how it is measured. In addition, @entity308 @entity1 with @entity1314 pathology appear less likely to receive adequate treatment in uncontrolled studies. Finally, studies rarely control for @entity308 characteristics (e.g., chronicity, severity) that may influence outcome and be related to @entity1314 pathology. Overall, the best-designed studies reported the least effect of @entity1314 pathology on @entity308 treatment outcome. Clinically, this suggests that comorbid @entity1314 pathology should not be seen as an impediment to good treatment response.
