Spectrum of pathogens in surgical site XXXX at a Swiss university hospital.

@entity1 @entity2261 @entity6081 @entity868 @entity526 @entity794 @entity281 @entity130
BACKGROUND: The type of surgical antimicrobial prophylaxis (SAP) is determined by the spectrum and antimicrobial resistance of pathogens causing surgical site @entity281 (SSI). The aim of this study was to define the microbiological features of SSI in general surgery @entity1 at Basel University Hospital in order to validate our current strategy of single-shot SAP with 1.5 g @entity2261 (plus 500 mg @entity868 in colorectal surgery). METHODS: A prospective observational cohort of consecutive vascular, visceral and @entity130 procedures was analysed to evaluate the incidence of SSI. @entity6081 and resulting @entity281 were assessed to centres for disease control standards. Microbiological evaluation was performed by microscopic direct preparation, cultures and testing for antibiotic resistance. RESULTS: A total of 293 instances of SSI were detected in this cohort of 6283 surgical procedures (4.7%). Microbiological species were identified in 129 of 293 SSI (44%). @entity794 (29.5%) was the most common pathogen causing SSI in @entity130 and vascular surgery, whereas @entity526 (20.9%) was more frequently responsible for SSI in visceral surgery. Importantly, not a single case of SSI was caused by antimicrobial-resistant pathogens in this series. CONCLUSIONS: The spectrum of pathogens causing SSI identified and the very low incidence of antimicrobial resistance at Basel University Hospital validate the continuous use of single-shot single-drug SAP with @entity2261 (plus @entity868 in colorectal surgery).
