[Studies On Pathological Changes Of The Liver In Abino XXXX Infected With @entity2440 ]

@entity82 @entity96 @entity14007 @entity281 @entity2440 @entity35 @entity1412
The present study was undertaken to observe the pathologic changes of the liver in albino @entity35 with @entity2440 . Twenty five @entity35 given 50 metacercariae respectively by mouth were autopsied at 3 days (group 1), one week (group 2), 4 weeks (group 3), 8 weeks (group 4) and 12 weeks (group 5) of @entity281 . The following results were obtained: 1. Parasites were seen in bile ducts of group 2, 3, 4, 5 and increased in number with duration of @entity281 . 2. The pathologic changes in the liver were prominent in intrahepatic bile ducts. Epithelial cells of bile ducts showed definite atypia and proliferation resulting in pseudostratification in group. Stratification of metaplastic squamous cells and glandular proliferation were prominent in group 3. The epithelial cells were keratinized with syncitium and cribriform formation in group 4 and almost suggestive of @entity1412 in group 5. 3. Periductal @entity82 seen in group 4 was considerable as well as mature with hyalinized connective tissue in group 5. 4. Heavy inflammatory cell infiltrations around the affected bile ducts in group 1 became smaller in number with duration of @entity281 . The inflammatory cells consisted of the majority of eosinophils in group 1 and chiefly plasma cells, lymphocytes and mononuclear cells in group 5. 5. Veins in portal spaces dilated markedly in group 1 became less prominent with duration of @entity281 . 6. Although portal @entity82 increased definitely in group 3 often extended into the hepatic lobules in group 4, the changes of hepatic cells, sinusoids and central veins were negligible. Above results suggest that @entity14007 could be a factor in inducing primary @entity96 in albino @entity35 .
