Insight into the Spectrum of XXXX in Asymptomatic Urban Han Chinese Population by Coronary Computed Tomography Angiography.

@entity3980 @entity453 @entity850 @entity731
OBJECTIVES: Highlighted the spectrum of @entity453 in asymptomatic population by Computed Tomography Angiography (CTA) and developed a surrogation of expensive CTA to early detect @entity453 . METHODS: Three hundred and seven self-referred urban Han Chinese asymptomatic individuals underwent coronary CTA were consecutively enrolled. Total plaque score (TPS), Segment @entity850 score (SSS) and @entity453 severity (CADS) were used to measure and illustrate the spectrum of @entity731 burden by mapping their incidence and proportion onto coronary artery tree. Logistic regression model was further used to explore the association between lipid biomarkers and TPS (SSS) for developing a surrogation of CTA to early detect @entity453 . RESULTS: We found that the incidence of TPS, SSS and CADS were up to 71.34%, 68.08%, and 71.34%; and high-risk individuals reached up to 11.07%, 15.31% and 16.29% respectively. All TPS, SSS and CADS were much higher in male than female, and have trend of increasing with age. The most lesion segment emerged on proximal @entity3980 , followed by proximal RCA, mid @entity3980 , proximal LCX, and mid RCA with mixed plaque as dominant. HDL-C was a predictor to both TPS [OR: 0.12 (0.02-0.82)] and SSS [OR: 0.15 (0.03-0.76)], and could identify the serious @entity731 subjects of TPS or SSS score >5 (AUC 0.73 and 0.70). CONCLUSIONS: The @entity731 plaque burden was about one in ten as high-risk individuals in this specific urban Han Chinese population. As potential surrogation of CTA, HDL-C was recognized as a significant predictor to @entity731 burden and revealed a good performance for identifying high-risk individuals.
