Efficacy of topical combination of @entity18575 5% and @entity3402 1% for the treatment of progressive XXXX : a randomized, doubleblind, placebo-controlled trial.

@entity1 @entity18575 @entity272 @entity1020 @entity3402
BACKGROUND: Progressive @entity1020 is @entity272 without definite etiology. There is no consensus or first-line therapy in the treatment of progressive @entity1020 , and the treatment options used are very little effective. OBJECTIVE: To evaluate the therapeutic efficacy of the topical combination of @entity18575 5% and @entity3402 1% associated with sun exposure for the treatment of progressive @entity1020 . MATERIALS AND METHODS: This is a randomized, double-blind, placebo-controlled study in which @entity1 were divided into two groups. Group A used the topical combination of @entity18575 5% and @entity3402 1% and Group B used gel cream as a placebo. @entity1 were advised to expose themselves to the sun on a daily basis and were systematically evaluated and photographed. The collected data were entered and analyzed using Epi Info. A p value < 0.05 was considered statistically significant. RESULTS: Out of the 23 @entity1 included in the study, 13 were in group A and 10 in group B. Eleven @entity1 (85%) in group A had significant clinical improvement and only two @entity1 (20%) in group B showed an equivalent clinical improvement (p = 0.003). Side effects were more frequent in group A (p = 0.003). CONCLUSION: The topical combination of @entity18575 5% and @entity3402 1% is effective in the treatment of progressive @entity1020 .
