[Significance of primary radical surgery for survival following treatment of @entity0 . Problems of interpretation of treatment results of prospective, nonrandomized studies exemplified by the Southwest Germany XXXX Study].

@entity1 @entity5 @entity0
In a prospective non-randomised trial 1642 @entity1 were included. After a mean time of 10 years a follow-up analysis was performed. The importance of the radicality of the primary operative therapy of @entity0 should be evaluated. The mean 5 years survival rate was 67.3%, the 10 year survival rate 51.6%. @entity5 stage and age had a highly significant influence on the survival rate. @entity1 with simple mastectomy had a lower survival rate as @entity1 with radical mastectomy. This apparent difference was caused by a different age distribution in the therapy groups. Accordingly the mean life deficiency was the lowest in the simple mastectomy group. In a multiple hazard statistical analysis @entity5 stage and age showed a highly significant influence on the survival rate. The intraoperative radicality classification showed a significant correlation to the prognoses of the @entity1 . The operative therapy itself had no significant influence on the survival rate of the @entity1 .
