Scheimpflug photography study of ophthalmic viscosurgical devices during simulated XXXX surgery.

@entity1707 @entity231 @entity4023 @entity8707 @entity597
PURPOSE: To evaluate by Scheimpflug photography the capacity of several commercially available ophthalmic viscosurgical devices (OVDs) to remain in the anterior chamber and maintain @entity8707 ( @entity8707 ) during simulated @entity231 surgery in porcine cadaver eyes. SETTING: Department of Preclinical Ophthalmology, Pharmacia _ Upjohn AB, Uppsala, Sweden. METHODS: Eighty eyes from newly slaughtered @entity1707 were used. They were distributed equally among 8 OVDs: Amvisc Plus ( @entity4023 1.6%), Biolon ( @entity4023 1.0%), Biolon Prime ( @entity4023 1.2%), Healon ( @entity4023 1.0%), Healon GV ( @entity4023 1.4%), Healon5 ( @entity4023 2.3%), Provisc ( @entity4023 1.0%), and Viscoat ( @entity4023 3.0%-chondroitin @entity597 4.0%). Scheimpflug photographs were taken using a Nidek EAS-1000 instrument before surgery (control), after injection of the OVD, after continuous curvilinear capsulorhexis (CCC), and after lens extraction by phacoemulsification. Differences in the @entity8707 with a P value less than 0.05 were considered statistically significant. The retention capacity was visually assessed. RESULTS: Healon5 had a significantly higher capacity to maintain the @entity8707 than the other OVDs after CCC and phacoemulsification. After injection, Healon5, Viscoat, and Biolon Prime showed similar @entity8707 -maintaining capacities. CONCLUSIONS: The capacity of Healon5 to maintain the @entity8707 during @entity231 surgery, ie, neutralizing the vitreous pressure and stabilizing the anterior segment of the eye, was significantly higher than that of the other OVDs.
