Safety and feasibility of prehospital thrombolysis in combination with active rescue PCI strategy for acute ST-elevation XXXX .

@entity1 @entity583 @entity64 @entity1779
BACKGROUND/OBJECTIVES: The purpose of this observational study was to provide an impression of the outcomes of prehospital thrombolysis in combination with an active coronary angioplasty intervention (PCI) strategy for acute ST-elevation @entity583 . METHODS: In a group of 151 consecutive @entity1 the following parameters were measured: time delay, percentage of reperfusion, reocclusion, @entity64 , death, need for PCI and the number of protocol violations. RESULTS: The diagnosis by the ambulance paramedics was made in 8  6 minutes, followed by thrombolysis in 13  7 minutes (median  SD). In 2% (3) of the @entity1 the thrombolytic agent was erroneously administered without complications. The elapsed time from onset of symptoms to treatment was a median of 112  77 minutes. Five percent (7) of the @entity1 died in the first 30 days and 2% (3) suffered an @entity1779 . Reperfusion was documented in 76% (112) of the @entity1 , from which 18% (20) reoccluded in the following 24 hours. In @entity1 where reperfusion was not established or reocclusion occurred, @entity1 underwent rescue/facilitated PCI: in total 37% (55 @entity1 ). After three months 9% (13) of the @entity1 had severly impaired (EF <40%) left ventricular function. CONCLUSION: In our region, we successfully implemented the prehospital thrombolysis system achieving a competitive call-to-needle time and reperfusion rate. The percentage of @entity1 who violated the protocol, suffered an @entity1779 , died and/or had severely impaired left ventricular function was acceptable.
