Significance of lymphadenectomy with splenectomy in radical surgery for advanced ( @entity1803 /pT4) XXXX .

@entity1 @entity2558 @entity1803 @entity5 @entity3 @entity356
BACKGROUND: To date, the optimal surgical strategy for @entity356 has not been determined. The purpose of this study was to clarify the significance of lymphadenectomy with splenectomy in @entity356 surgery. METHODS: This retrospective cohort study was conducted at the Kumamoto Regional Medical Center. The primary endpoint was overall survival after surgery. We retrospectively analyzed the clinicopathologic features, surgical treatments, and long-term prognosis of @entity356 @entity1 treated with total gastrectomy. RESULTS: A total of 80 @entity1 with @entity356 in the remnant stomach after distal gastrectomy and who underwent total gastrectomy were enrolled in the study. Splenectomy was performed in 38 @entity1 . Lymph node @entity3 in the splenic hilum was not observed in the @entity1 with @entity2558 /pT2 @entity5 , whereas nodal @entity3 at the splenic hilum was detected in 30.4% of the @entity1 with @entity1803 /pT4 @entity5 . The survival rate of the @entity1 with @entity1803 /pT4 @entity5 who underwent splenectomy was significantly higher than that of the @entity1 who did not undergo splenectomy, although there was no difference in the @entity1 with @entity2558 /pT2 @entity5 . Among the @entity1 classified as R0, the survival rate of the @entity1 with @entity1803 /pT4 @entity5 who underwent splenectomy was significantly higher than that of the @entity1 who did not undergo splenectomy. CONCLUSION: Lymphadenectomy with splenectomy in radical surgery is beneficial for @entity1 with advanced ( @entity1803 /pT4) @entity356 .
