Correlation between the flow pattern of the circle of Willis and segmental perfusion asymmetry after XXXX revascularization.

@entity1 @entity291 @entity2998
BACKGROUND:     To correlate cerebral perfusion and flow patterns after @entity2998 revascularization within the circle of Willis ( @entity291 ). METHODS:     Sixty-five @entity1 (male/female ratio: 38/27; mean age: 63.2  8.4years; range: 44-82years) with symptomatic @entity2998 stenosis underwent magnetic resonance (MR) angiography and perfusion imaging prior to and after @entity2998 stenting (CAS). Regions of interest (ROIs) on the MR perfusion maps included the corona radiata (CR), centrum semiovale (CSO), occipital region (O), and basal ganglia region (BA) in both stented and non-stented hemispheres. The non-stented hemisphere was used as internal control. RESULTS:     Subjects were assigned to the altered @entity291 group (N=31) vs. the static @entity291 group (N=34). Thirty-one subjects (47.6%) had an altered flow pattern in the @entity291 after CAS, and thirty-four (52.4%) retained a static @entity291 configuration. Relative cerebral blood volume (rCBV) interhemispheric index correlated with @entity291 morphologic alterations after carotid stenting. Altered @entity291 group had a higher regional interhemispheric index of rCBV in the CR (1.23  0.15 vs. 0.87  0.13; P=0.03) and basal ganglia (1.25  0.12 vs. 0.91  0.11; P=0.03) compared to the static group. CONCLUSIONS:     An association between the regional cerebral blood volume (rCBV) interhemispheric asymmetry and @entity291 collateralization was observed. In addition, the CR, rather than CSO, was found to have topographic significance.
