[Pure endoscopic endonasal transsphenoidal approach for 375 XXXX ].

@entity1 @entity49544 @entity227 @entity1415 @entity772 @entity2895 @entity2124 @entity693 @entity5173 @entity977 @entity652 @entity10759 @entity2010
OBJECTIVE: To describe the experience with surgical treatment of @entity977 via a fully transnasal endoscopic approach. METHODS: Clinical records of 375 cases with @entity977 underwent pure endoscopic operations between December 2006 and December 2009 were carefully assembled. Among 375 pure endoscopic operations of @entity977 , 201 cases were nonfunctional @entity652 and 174 cases were functional @entity652 . There were 27 giant @entity977 (7.2%) and 41 @entity977 invaded cavernous sinus (10.9%). Intraoperative 1.5 T MRI and neuro-navigation system were used during some operations. The postoperative and follow-up data of @entity1 were analyzed. RESULTS: There were 234 (79.3%) cases of total resection, 56 (19.0%) cases of subtotal resection, 5 (1.7%) cases of partial resection. Sixty-eight @entity1 had vision improved in 73 @entity1 with vision decreasing before operation. Sixty-eight (77.3%) @entity1 got normal endocrine in 88 @entity49544 @entity1 . Fifty-five (84.1%) @entity1 got normal @entity2124 in 63 @entity1 with @entity10759 . Eighteen (78.2%) @entity1 got normal in 23 @entity1 with corticotrophinoma. These was no death case in this group. One case (0.3%) suffered @entity772 . Transient @entity227 occurred in 2 cases (0.5%). Transient @entity2895 or abducens nerve occurred in 7 cases of operations involved cavernous sinus. Three (0.8%) @entity1 had @entity693 . Two @entity1 (0.5%) suffered from @entity5173 but none underwent operation to repair. Fourteen @entity1 (3.7%) had transient @entity2010 . Six @entity1 (1.6%) had @entity1415 . CONCLUSIONS: Trans-nasal endoscopy provides a new device for operation of @entity977 which is effective and safe. Comparing with microscope, endoscopic visual field is clearer, closer and wider.
