Availability of tissue rinse liquid-based cytology for the rapid diagnosis of sentinel lymph node XXXX and improved bilateral detection by photodynamic eye camera.

@entity1 @entity1136 @entity5 @entity3846 @entity3
OBJECTIVE: On sentinel lymph node navigation surgery for early @entity3 , to gain high sensitivity and specificity, the sentinel nodes should be detected bilaterally and pathological diagnosis should be sensitive to detect micrometastasis. To improve these problems, we tried tissue rinse liquid-based cytology and the photodynamic eye. METHODS: From 2005 to 2013, 102 @entity1 with Stage @entity3846 uterine cervical @entity5 were subjected to sentinel lymph node navigation surgery with @entity1136 -99 m colloid and blue dye. For the recent 11 @entity1 with whom bilateral sentinel node detection was not available, the photodynamic eye was selectively examined. The detected sentinel node was cut along the minor axis into 2 mm slices, soaked in 10 ml CytoRich red and then subjected to tissue rinse liquid-based cytology at the time of surgery. RESULTS: With the accumulation of 102 @entity3846 @entity1 subjected to sentinel lymph node navigation surgery, the bilateral sentinel node detection rate was 67.7%. The photodynamic eye was examined for the recent 11 @entity1 who did not have bilateral signals. Out of the 11, 10 @entity1 obtained bilateral signals successfully. During the period of examining the photodynamic eye, a total of 34 @entity1 were subjected to sentinel lymph node navigation surgery. Thus, the overall bilateral detection rate increased to 97% in this subset. Two hundred and five lymph nodes were available as sentinel nodes. The sensitivity of tissue rinse liquid-based cytology was 91.7%, and the specificity was 100%. False positivity was 0% and false negativity was 8.3%. Detection failure was observed only with one micrometastasis and one case of @entity5 cells. CONCLUSION: Combination of photodynamic eye detection and tissue rinse liquid-based cytology pathology can be a promising method for more rewarding sentinel node detection.
