Prognostic factors in XXXX .

@entity1 @entity6592 @entity851 @entity625 @entity1530 @entity1596 @entity170 @entity4932 @entity2124 @entity221
Prognostic factors in @entity625 are related to many variables that must be evaluated according to the different subtypes. The International League of Associations of Rheumatologists (ILAR) recently proposed six different categories referred to as the Durban criteria, under the eponym of @entity4932 ( @entity4932 ). The aim of this classification was to define homogeneous groups according to their clinical and biologic features. The prognostic factors were classified into the different categories of @entity4932 . A poor outcome in the systemic form correlated with markers of disease activity, such as @entity221 , within the first 6 months. The risk of joint destruction in @entity4932 correlated with the severity of @entity625 within the first 2 years. @entity625 with positive rheumatoid factor is associated with marked disability in adulthood. In a group of psoriatic @entity1 , the risk of developing @entity6592 is higher in male and @entity1530 27-positive @entity1 . @entity1 with @entity4932 with lower limb, knee, and tarsal involvement also are at greater risk of developing @entity6592 . @entity1596 is a complication of @entity4932 observed mainly in @entity1 with @entity4932 associated with positive antinuclear antibodies in serum. Secondary amyloidosis is observed mainly in @entity1 with systemic @entity4932 . The long-term outcome must be discussed according to the various therapies. Corticosteroids contribute to @entity851 and @entity170 , for which the use of @entity1 recombinant @entity2124 and biphosphonates may be an option. Newer encouraging therapies such as anticytokines have been proposed for @entity1 with active disease. Autologous stem cell transplantation is being evaluated in some centers with promising results; however, it has a high rate of mortality. Further discussion regarding which @entity1 should undergo autologous stem cell transplantation is needed, as is further discussion regarding the technical adaptations necessary.
