XXXX and other adverse reactions to foods.

@entity1 @entity5419 @entity6766 @entity8610 @entity3009 @entity9992 @entity230
Adverse reactions to foods do occur. Their true degree of prevalence remains unknown. Many mechanisms are involved, including events at the gut mucosa surface, immunologic pathways, and nonimmunologic and possibly genetic influences, not all of which have yet been well studied. The major manifestations of @entity5419 have been cutaneous, gastrointestinal, and pulmonary. Others are less convincingly established. Of particular interest is the likelihood that certain rheumatic symptoms may be related to @entity6766 . Establishing a diagnosis of adverse food reaction requires thoughtful clinical evaluation and laboratory testing, confirmatory immunologic studies, and double-blind food challenge. Skin testing is a valuable screening tool and can help direct the physician to those @entity1 for whom double-blind food challenge may be indicated. The simplest therapy is avoidance of foods to which an individual is sensitive. @entity9992 , @entity8610 , @entity3009 synthetase inhibitors, and @entity230 have been used, but their efficacy has not yet been carefully evaluated.
