Training-related improvements in musculoskeletal health and balance: a 13-week pilot study of female XXXX survivors.

@entity1 @entity174 @entity2301 @entity5 @entity442 @entity79 @entity18527
UNASSIGNED: @entity5 survivors often experience poor post-treatment musculoskeletal health. This study examined the feasibility of combined aerobic and resistant training ( @entity18527 ) for improving strength, skeletal health and balance. @entity5 survivors (n  =  24) were identified by convenience sampling in Los Angeles County with 11 survivors consenting to 13  weeks of @entity18527 . Pre- and post-intervention assessments of @entity79 ( @entity79 ), strength, flexibility and biomarker analysis were performed. Paired t-test analysis suggested increases in lower and upper body strength. The average T-score for @entity79 at the femoral neck improved from -1.46 to -1.36 and whole body @entity79 improved from -1.65 to -1.55. From baseline to follow-up, @entity1 also displayed decreases in sway velocity on the eyes open (7%) and eyes closed (27%) conditions. Improvement in lower body strength was associated with increases in lean body mass (LBM) (r  =  0.721) and an inverse association was observed between sway velocity and LBM (r  =  0.838). Age and time since last treatment were related with biomarkers of anabolic growth ( @entity442 , @entity2301 ) and bone (DPD, BAP). In summary, observed physiological changes were consistent with functional improvements, suggesting that isometric and dynamic exercise prescription may reduce the risk for falls and fall-related @entity174 among survivors.
