Pregnancy Outcomes After Abdominal Radical Trachelectomy for Early-Stage Cervical XXXX : A 13-Year Experience in a Single Tertiary-Care Center.

@entity1 @entity9216 @entity548 @entity7288 @entity5 @entity957 @entity5870 @entity3846 @entity1358 @entity9217 @entity420
OBJECTIVE: To investigate pregnancy outcomes in @entity1 after abdominal radical trachelectomy (RT) for @entity5 . METHODS: The @entity1 ' background, fertility, and pregnancy outcomes were reviewed in a total of 61 pregnancies in 48 of 172 @entity1 who underwent abdominal RT at Keio University Hospital between September 2002 and December 2013. RESULTS: There were 5 @entity1 with stage @entity9216 , 2 with stage @entity9217 , and 41 with stage @entity3846 . Histological types were as follows: @entity957 (n = 36), @entity420 (n = 10), and @entity1358 (n = 2). The pregnancy rate of @entity1 attempting to conceive after abdominal RT was 44% (48/109). The mean    SD duration from abdominal RT to conception was 3.1    1.9 years. Of 61 pregnancies, 42 pregnancies were achieved by fertility treatment (in vitro fertilization-embryo transfer, 39; intrauterine insemination, 3). After excluding one pregnancy without detailed clinical information, there were 42 live births (5 in 22-27 weeks, 11 in 28-33weeks, 20 in 34-36 weeks, and 6 in 37-38 weeks), 13 miscarriages, and 5 ongoing pregnancies. While there were 10 first trimester miscarriages, 3 pregnancies ended in the second trimester owing to @entity5870 . The mean gestational age at birth was 33 weeks of pregnancy. Thirty-seven neonates were appropriate-for-date, and one was small-for-date. Six pregnancies exhibited @entity548 from the residual cervix in the late pregnancy. Preterm birth less than 34 weeks of pregnancy was related to premature rupture of the membrane (P < 0.05). @entity5870 was evident in 9 of 11 pregnancies with preterm premature rupture of the membrane followed by birth at less than 34 weeks of pregnancy. No parturients exhibited lochiometra and @entity7288 . CONCLUSIONS: Abdominal RT provided favorable pregnancy outcomes, and fertility treatment could be advantageous to conception. Massive @entity548 from the residual cervix as well as ascending infection might be characteristic features during pregnancy after abdominal RT.
