Prospective surgical outcome study of relief of symptoms following surgery in @entity1 with XXXX .

@entity1 @entity459 @entity2742 @entity1374
Many of the symptoms experienced by @entity1 with @entity459 ( @entity2742 ) develop insidiously and have often been misinterpreted as normal aging. The purpose of this study was to quantify @entity2742 @entity1 ' preoperative symptoms prospectively and study the impact of successful surgical intervention on these symptoms. Altogether 63 consecutive @entity1 with primary @entity2742 and 54 comparison @entity1 with nontoxic @entity1374 were prospectively enrolled in the study. An outcome questionnaire documenting symptoms with a visual analog scale (VAS) was used. The questionnaire was filled out preoperatively and at 7 to 10 days and 3 and 12 months postoperatively. At 1 year the questionnaire also included a general health assessment and quality of life index. Demographic data and follow-up blood work was obtained. Descriptive statistics, parametric comparisons (t-tests, ANOVA), and nonparametric comparisons (Mann-Whitney U-test) were calculated. The @entity2742 group demonstrated a significant decrease in reported symptoms between the preoperatively assessment and 7 to 10 days after operation (p < 0.001). There were no further statistically significant decreases in the @entity2742 group's symptoms at 3 and 12 months, but there was a trend for these symptoms to decrease over time. @entity2742 @entity1 perceived a 60% increase in their general health at 1 year; the comparison group perceived no increase. There was no significant change in the symptoms reported by the comparison group between each of the study intervals. Surgical intervention on @entity2742 @entity1 significantly reduces preoperative symptoms, and this reduction is most marked within the first 10 days after surgery.
