[ XXXX complicated by testicular @entity10524 : one-case clinical analysis].

@entity1 @entity1420 @entity2494 @entity1887 @entity619 @entity8302 @entity1062 @entity10524 @entity774
OBJECTIVE: To investigate the early diagnosis and treatment of @entity774 ( @entity774 ) complicated by testicular @entity10524 (TART). METHODS: We retrospectively analyzed the clinical data of 1 case of late-onset @entity774 complicated by TART diagnosed and treated in Xiamen @entity1 and @entity1 Health Care Hospital. RESULTS: The @entity1 was a 15 years old @entity1 , short statured and dark skinned, with skin pigmentation in the gum and external genital, secondary sex characteristics of the adult and irregular tubercles palpable in the bilateral testes. Laboratory examinations showed obviously increased levels of ACTH, 17-KS, @entity2494 -S and @entity1420 and evidently decreased levels of FSH, LH and CO. The low-dose @entity619 suppression test reduced ACTH and @entity2494 -S to normal. Imaging examinations revealed soft tissue density in the bilateral adrenal glands, especially on the right, and irregularly increased volume of the bilateral testes, particularly on the left, with heterogeneous signals and septas and surrounded by the fluid signals. Histopathological examinations showed the eosinophilic cytoplasm to be polygon- or round-shaped, interstitium-like cells arranged in line, and lipopigment in the endochylema. Immunohistochemical results were negative for @entity8302 . The clinical signs of the @entity1 were improved after 3 months of @entity619 treatment, the hyperplastic nodules in the left @entity1062 decreased obviously and those in the right @entity1062 disappeared after 6 months, and the hyperplastic nodules in the adrenal glands vanished after 9 months. CONCLUSION: Based on the clinical manifestations and the results of auxiliary examinations, this case was diagnosed as late-onset @entity774 complicated by TART, which was attributed to the continued surge of ACTH induced by @entity1887 . Sufficient @entity619 treatment could make the TART decrease or disappear and the @entity774 vanish; it could also improve the clinical symptoms and bring the laboratory results to normal.
