Pubertal development and final height after autologous bone marrow transplantation for XXXX .

@entity1 @entity981 @entity2082 @entity2124 @entity348 @entity1176 @entity2746
We describe pubertal development and growth in 17 @entity1 who underwent bone marrow transplantation (BMT), including @entity348 ( @entity348 ) for @entity981 . Seven @entity1 also received cranial irradiation (CI) and five @entity1 testicular irradiation. All underwent transplantation before (n=15) or at the beginning of (n=2) puberty and reached a final height (FH). Puberty started spontaneously in all @entity1 not given testicular irradiation. All @entity1 who received testicular irradiation developed @entity2746 . Puberty started spontaneously in two @entity1 and was induced with increasing doses of @entity2082 in two @entity1 . In two @entity1 , a low dose of @entity2082 was given until menarche. In one @entity1 with early onset of puberty and short stature, puberty was blocked with a @entity1176 analogue. The standard deviation score for height decreased significantly from BMT to FH, both in the @entity1 who received @entity348 only (-1.1, P=0.005) as well as in those given additional CI (-1.7, P=0.027). Most of the loss occurred during puberty. In all, 10 @entity1 received @entity2124 ( @entity2124 ) treatment. CI, young age at BMT, and short duration of @entity2124 treatment were predictors of height loss after BMT. Although limited by the small and heterogeneous sample, our study supports the use of early @entity2124 treatment in @entity1 with decelerating growth rate and low @entity2124 levels.
