Successful Live Birth in a @entity1 With @entity814 Through XXXX Frozen-Thawed Embryo Transfer.

@entity1 @entity249 @entity2691 @entity1420 @entity9667 @entity147 @entity814 @entity53 @entity72370 @entity72371 @entity619 @entity74 @entity52 @entity2588 @entity774
CONTEXT: @entity774 ( @entity774 ) due to @entity814 in 46,XX @entity1 is characterized by primary @entity2588 , absent or incomplete sexual maturation, @entity249 , low serum levels of @entity53 , and elevated @entity1420 (P). There were no previous reports of singleton live births from such @entity1 . OBJECTIVE: To describe the first successful singleton live birth in a female with @entity774 due to @entity814 . CASE DESCRIPTION: A 26-year-old Brazilian @entity1 with @entity774 associated with @entity814 due to the compound heterozygote mutation ( @entity72370 / @entity72371 ) in the @entity9667 gene expressed the desire to conceive. @entity52 ( @entity52 ) was recommended due to the @entity74 . The first attempt of treatment failed despite the production of viable embryos. At the second @entity52 attempt, all viable embryos were frozen due to inadequate endometrial development associated with prematurely elevated serum P during ovarian stimulation. Subsequently, a long-acting GnRH agonist and oral @entity619 were used to lower ovarian and adrenal P overproduction. Once serum levels of P were < 1 ng/mL, endometrial preparation with @entity2691 and frozen-thawed embryo transfer were performed, resulting in a singleton pregnancy. @entity53 supplementation was completely suspended by 14 weeks of gestation. She delivered at 30 weeks and 4 days due to @entity147 . The puerperium was uneventful; the newborn was discharged in good conditions 5 weeks after birth. CONCLUSION: A successful live birth was achieved in a @entity1 with 17-hydroxylase deficiency through @entity52 , cryopreservation of all embryos, and frozen-thawed embryo transfer after adequate endometrial preparation.
