Distribution of overnight @entity4 across subjects with 4 different XXXX hydrogel lenses.

@entity1 @entity4 @entity26 @entity57736 @entity735 @entity1346
PURPOSE: To determine distribution of central @entity4 (CCS) across subjects after 8 hr of @entity735 wearing @entity1346 hydrogel lenses with various @entity26 transmissibility (Dk/t) values and in eyes without lenses. METHODS: Twenty-nine neophytes wore lotrafilcon A (Dk, 140), balafilcon A (Dk, 91), @entity57736 (Dk, 60), and senofilcon A (Dk, 103) lenses in powers -3.00, -10.00, and +6.00 diopters on separate nights, in random order, and on 1 eye only. The contralateral eye (no lens) served as the control. Central corneal thickness was measured using a digital optical pachometer before lens insertion and immediately after lens removal on waking. RESULTS: The average difference between the mean (7%) and the median (6.8%) CCS of all lenses was only 0.2%, suggesting a normal distribution. There was no correlation between the mean and the range of the CCS (r=0.058, P=0.766). Normal CCS distributions were also found with each @entity735 and the control eye (P>0.20 for all). There was a significant correlation between @entity735 (r=0.895, P<0.001) and between lotrafilcon A and each of the other 3 lenses for mean CCS across the study @entity1 (P<0.001 for all). CONCLUSIONS: Distribution of @entity4 in both @entity735 followed a normal curve. An individual's @entity4 response seems to be independent of lens type.
