Long-term results and complications of botulinum A toxin in the treatment of XXXX .

@entity1 @entity892 @entity2473 @entity936 @entity9663 @entity3519 @entity1736 @entity3917
The authors review their long-term results and complications with the use of botulinum A toxin in the treatment of @entity3519 . Two hundred thirty-two @entity1 in three diagnostic groups--essential @entity9663 , hemifacial @entity2473 , and Meige's syndrome--were treated with botulinum A toxin. A total of 1044 treatments were given over a 4-year period. A reduction in orbicularis @entity2473 intensity was noted in 1012 (96.9%) treatments (mean duration, 13.3 weeks). There was no clear relationship between toxin dose and the amount of @entity2473 reduction or duration of response, and average duration of beneficial effect remained constant from the first through the twelfth injections. Complications occurred in 236 (22.6%) treatments. In most cases, these were local and transient. Symptomatic @entity936 was the most common side effect, noted in 7.5% of cases. @entity1736 was reported in 7.3% of treatments and @entity3917 in 2.5%. @entity892 involving the inferior oblique or lateral rectus muscles was seen in less than 1% of cases. There were no differences in degree of response or in complications among the three diagnostic groups, although there was a slight difference in duration of effect. @entity1 who had undergone previous eyelid surgery for @entity9663 did not respond differently from those without prior surgery.
