[Acute kidney injury and renal replacement therapy in victims from out-of-hospital XXXX with administration of contrast agent].

@entity1 @entity810 @entity299 @entity1011 @entity1167
BACKGROUND: Early coronary angiography and computed tomography are recommended in survivors of out-of-hospital @entity1167 (OHCA). However, both techniques require iodinated contrast agent although the effects on incident @entity810 are unknown. The aim of this study was to explore the incidence of @entity810 ( @entity810 ) and need for renal replacement therapy (RRT) in @entity1 after nontraumatic OHCA with special regard to the administration of contrast agent during the early in-hospital diagnostic workup. MATERIALS AND METHODS: Data from all survivors of OHCA admitted to our hospital between 1  January  2008 and 30  June  2015 were retrospectively collected. Incidence of @entity810 and RRT between the contrast and no contrast groups were compared. RESULTS: Of 280  OHCA survivors, 133 (47.5   %) received contrast agent (227.0        136.5  ml). Within 72  h after hospital admission, 47 of 129 survivors (36.4   %) developed @entity810 of any stage, but @entity810 was more common in @entity1 without early contrast administration than in @entity1 with early contrast administration (54.5 vs. 28.2   %; p   =   0.011). @entity1 who survived until hospital discharge had higher serum @entity1011 levels at admission than at hospital discharge (1.17        0.37 vs. 0.92        0.35; p   <   0.001). CONCLUSION: @entity810 is common in survivors of OHCA, and RRT following OHCA is needed more frequently than in other @entity299 . Despite elevated serum @entity1011 levels at admission, we could not show an association between early contrast administration in survivors of OHCA and @entity810 incidence.
