Fluid resuscitation in XXXX @entity1 .

@entity1 @entity1545 @entity32 @entity2332 @entity548 @entity520 @entity2421 @entity1230 @entity551 @entity130
PURPOSE OF REVIEW: Fluid resuscitation in @entity130 @entity1 with @entity548 is controversially discussed in the literature. The coincidence of @entity1545 complicates management of these @entity1 . This article summarizes the current knowledge on nonblood component fluid resuscitation and choice of fluids in @entity1 with @entity1230 . RECENT FINDINGS: Whereas current evidence suggests the efficacy of fluid therapy in @entity548 without active @entity548 , experimental and clinical data demonstrate that aggressive volume challenge may be futile or even deleterious in the setting of uncontrolled @entity548 . Large amounts of isotonic crystalloids may be associated with @entity2332 , @entity520 and @entity32 . In @entity1 with traumatic @entity1545 hypertonic solutions may positively influence @entity32 and intracranial pressure without affecting neurologic outcome or mortality. SUMMARY: To date no large-scale clinical studies exist to either support or refute the use of nonblood component fluid resuscitation of @entity548 in @entity130 @entity1 . The optimal choice of fluid remains to be determined, but existing evidence suggests avoiding crystalloids in favor of hypertonic solutions. The role of modern, iso-oncotic colloids in the treatment of @entity548 has not yet been sufficiently defined. In @entity1 with concomitant @entity1545 , arterial @entity551 must be avoided and infusion of @entity2421 solutions is obsolete, whereas administration of hypertonic solutions may exert beneficial effects beyond hemodynamic stabilization.
