Sensitivity and specificity of Heidelberg Retinal Tomography II parameters in detecting early and moderate XXXX : effect of disc size.

@entity1 @entity16 @entity726 @entity735 @entity989
PURPOSE: To determine the efficacy of Heidelberg Retinal Tomography II (HRTII) parameters in differentiating @entity735 with early or moderate @entity16 . METHODS: HRTII tests were performed on 70 eyes of 70 @entity1 with early or moderate @entity16 , and 70 eyes of 70 healthy subjects. HRTII stereometric parameters, global and sectorial rim area parameters were recorded. Sensitivity and specificity of each parameter were calculated. Cases were divided into three groups according to disc size as large, medium and small, and mean values of parameters in @entity726 and control groups were compared. RESULTS: Mean disc area was larger in the @entity726 group (P < 0.05). There was a significant difference between the two groups for all stereometric parameters, except height variation contour, mean @entity989 fibre layer thickness and @entity989 fibre layer cross-sectional area stereometric parameters. There was also a significant difference between the groups for global, temporal, superior temporal and inferior temporal rim area parameters. In small discs, however, this difference disappeared in all parameters except temporal rim area and superior temporal rim area sectorial parameters. When all the cases were included, the quartet parameters having the highest specificity (80%) and sensitivity (74.3%) were cup volume, rim volume, cup shape measure and height variation contour parameters. CONCLUSION: Some HRTII parameters have better sensitivity and specificity than the others. It is necessary to pay special attention in evaluating small discs.
