Aqueous humor analysis as a diagnostic tool in XXXX .

@entity1 @entity231 @entity1596 @entity6519 @entity791
Analysis of local toxoplasma antibody production to confirm a suspected clinical diagnosis of @entity6519 is a valuable diagnostic tool. Determination of toxoplasma antibodies in the blood of the @entity1 is of limited use. When blood toxoplasma tests are negative this indicates that toxoplasma as a causative organisms in the pathogenesis of @entity1596 is unlikely. A positive blood test is a sensitive test (100% @entity1 positive) but not a specific test since so many healthy individuals already have undergone subclinical infection and have acquired humoral immunity against the parasite. We analysed 93 paired aqueous and serum samples for toxoplasma antibodies and total IgG and determined the Goldmann-Wittmer coefficient. In @entity1 retrospectively diagnosed as having @entity6519 16 out of 22 had a positive coefficient, indicating local parasite antibody production. In one @entity1 with @entity791 we also found a positive toxoplasma coefficient. Three out of 15 @entity1 with posterior @entity1596 of unknown origin also had a positive coefficient. None of the @entity231 @entity1 tested (n = 32) had a positive coefficient. Major drawbacks of aqueous humor analysis are that a false negative antibody coefficient can occur when a massive blood aqueous barrier breakdown has occurred.
