@entity465 and XXXX in long-term mineral oil administration.

@entity1 @entity3329 @entity738 @entity39 @entity4988 @entity1066 @entity5132 @entity1897 @entity465 @entity236 @entity116 @entity792
BACKGROUND: Subcutaneous mineral oil injection is an old-fashioned practice used mostly for cosmetic purposes. Infection, @entity1066 , subcutaneous nodules, and autoimmune activation are among the known adverse effects. @entity465 has not been previously reported in association with mineral oil injection. OBJECTIVE: To report the case of a 43-year-old @entity1 who performed long-term self-administration of mineral oil and was found to have both cellular immunodeficiency and @entity792 . METHODS: We performed an immunological evaluation. Throat, induced sputum, urine, and blood cultures were examined for microorganisms. Pelvic computed tomography, inguinal lymph node biopsy, bone marrow biopsy, and liver biopsy were also performed. RESULTS: Laboratory results revealed @entity1897 , very low absolute numbers of lymphocyte subpopulations, and a markedly impaired lymphocyte proliferative response to mitogens (phytohemagglutinin and concanavalin A) and recall antigens (mumps, @entity5132 , purified protein derivative, and @entity116 toxoid). The cultures were negative for microorganisms. The pelvic computed tomogram demonstrated areas of diffuse oil-density signals throughout the subcutaneous tissue in the gluteal area and proximal lower extremities, as well as bilateral @entity3329 . A lymph node biopsy specimen showed lipid @entity738 and @entity39 . A bone marrow biopsy specimen demonstrated @entity236 with normal trilineage hematopoesis. Increased serum transaminase levels, @entity4988 , positive anti-extractable nuclear antigen and anti-Ro antibodies, and plasma cells in the liver suggested an autoimmune process. CONCLUSIONS: Mineral oil administration may be associated with both cellular immunodeficiency and @entity792 . @entity1 who have received long-term administration of a foreign substance should undergo a comprehensive immunological evaluation.
