XXXX and @entity3270 of the nasal cavity: a proposed new classification.

@entity1 @entity6012 @entity5 @entity189 @entity4236 @entity3 @entity521 @entity204 @entity420 @entity3270
The histologic characteristics of 29 nasal @entity5 previously diagnosed as @entity521 , unclassified @entity189 , or unclassified @entity5 were reviewed. Electron microscopy was performed in 17. Nine @entity5 were @entity521 ; six of these were classical @entity521 while the other three exhibited olfactory differentiation in addition to the classical @entity521 component. Areas of @entity6012 were found in the @entity3 of one of the three @entity4236 . @entity5 were classified as @entity3270 because all showed a neuroendocrine pattern with remarkably uniform cells growing from benign glandular epithelium; membrane bound granules were present in the cytoplasm of cells of the ten cases in this group examined by electron microscopy. The mean age of the @entity1 with @entity521 was 20 years; survival in this group was 75% at five and seven years, respectively, and 67% at ten years. Recurrences, @entity3 , and @entity204 occurred within 3 years of diagnosis. There was a low percentage (25%) of multiple recurrences. The @entity3 were located in cervical lymph nodes, brain and spine. The mean age of the @entity1 with @entity3270 was 50 years. Survival was 100% at five years, 88% at seven years, and 77% at ten years. Recurrences and @entity3 in 70% of the cases occurred later than the third year. Multiple recurrences were present in 54% of the cases. The @entity3 affected lymph nodes, brain and spine in all cases except in one in which lungs and femur were involved. In the latter case @entity420 was also present in addition to the @entity3270 . Three @entity1 died, all more than five years from the time of diagnosis. No correlation was found between staging and prognosis in either group, except for Stage I disease.
