Branched-chain XXXX supplementation enhances exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion.

@entity1522 @entity16623 @entity1576 @entity880 @entity1718 @entity413
AIM: It has been demonstrated that branched-chain @entity1522 (BCAA) transaminase activation occurs simultaneously with exercise-induced muscle glycogen reduction, suggesting that BCAA supplementation might play an energetic role in this condition. This study aimed to test whether BCAA supplementation enhances exercise capacity and lipid oxidation in glycogen-depleted subjects. METHODS: Using a double-blind cross-over design, volunteers (N.=7) were randomly assigned to either the BCAA (300 mg . kg . day -1) or the placebo (maltodextrine) for 3 days. On the second day, subjects were submitted to an exercise-induced glycogen depletion protocol. They then performed an exhaustive exercise test on the third day, after which time to exhaustion, @entity1576 ( @entity1576 ), plasma @entity413 , free @entity1718 (FFA), blood @entity16623 and @entity880 were determined. BCAA supplementation promoted a greater resistance to fatigue when compared to the placebo (+17.2%). Moreover, subjects supplemented with BCAA showed reduced @entity1576 and higher plasma @entity413 levels during the exhaustive exercise test. CONCLUSION: In conclusion, BCAA supplementation increases resistance to fatigue and enhances lipid oxidation during exercise in glycogen-depleted subjects.
