Evaluation of PICC complications in orthopedic inpatients with XXXX for long-term intravenous antibiotics therapy.

@entity1 @entity796 @entity146 @entity79 @entity281 @entity2458 @entity715
PURPOSE: The purpose of this study is to evaluate the complications of peripherally inserted central catheters (PICCs) in orthopedic @entity1 with chronic @entity79 . MATERIALS AND METHODS: The institutional review board approved this retrospective study and informed consent was waived. Records of 180 consecutives PICCs placed in @entity1 hospitalized in the orthopedic surgery department were reviewed. All @entity1 had @entity79 necessitating a long-term intravenous antibiotics therapy. All PICC complications were recorded during the @entity1 hospitalization: infection [catheter-related @entity281 (CRBSI), central line associated @entity281 (CLABSI), exit-site infection, @entity2458 ], @entity715 , occlusion, mechanical complication (accidental withdrawal, @entity146 ). RESULTS: One hundred and eighty PICCs were placed in 136 @entity1 . Mean duration of catheterization was 21 days (total 3911 PICC-days). Thirty-six PICCs (20%) were removed due to complications (9.2 complications per 1000 PICC-days): 14 (8%) infections (one CRBSI ( @entity796 ), one @entity2458 ( @entity796 ), two exit-site infections and 10 CLABSIs), 11 (6%) occlusions, and 12 (7%) mechanical complications (10 accidental withdrawals, one malposition, one median nerve irritation). One @entity1 had two complications simultaneously. After multivariate analysis, two risk factors were significantly associated with the overall occurrence of complications: age more than 70 years [OR = 2.89 (1.06-7.89], p = 0.04] and number of lumen at least two [OR = 2.64 (1.03-6.75), p = 0.04]. CONCLUSIONS: Even in orthopedic @entity1 with @entity79 , PICCs have a low rate of complication. The increasing lumen number of the PICC is a potential risk factor in our series.
