Histologic and Immunohistochemical Findings of a XXXX Immature Permanent Tooth with @entity1546 after Regenerative Endodontic Treatment.

@entity1 @entity1546 @entity11624 @entity1548
INTRODUCTION: Specimens of @entity1 immature permanent teeth after @entity11624 ( @entity11624 ) are sparse. This case report describes the histologic and immunohistochemical findings of tissue formed in the canal space of a @entity1 immature permanent tooth with @entity1546 after @entity11624 . METHODS: A @entity1 presenting with immature @entity1 permanent tooth #29  with @entity1546 underwent @entity11624 . At the 10-month follow-up visit, radiographic examination revealed @entity1548 , marked narrowing of the apical foramen, increased thickness of the canal walls, and minimal lengthening of the root. Notably, the tooth regained pulp sensibility. Tooth #29 was extracted for orthodontic reasons and processed for histologic and immunohistochemical examination. RESULTS: The canal space was filled with newly formed cementumlike tissue, bonelike tissue, and fibrous connective tissue. The apical closure, thickness, and length increment of the root were caused by the deposition of cementumlike tissue without dentin. Furthermore, neurons and nerve fibers were observed in the canal space; this observation was confirmed by immunohistochemistry. CONCLUSIONS: Based on the findings in the present case, after @entity11624 , the newly formed tissues in the canal space of the @entity1 immature permanent tooth with @entity1546 were primarily fibrous connective tissue, cementumlike tissue, and bonelike tissue. Nerve regeneration was identified.
