Spinal Bone Texture Assessed by Trabecular Bone Score in Adolescent @entity1 With XXXX .

@entity1 @entity174 @entity170 @entity1278 @entity79 @entity14257 @entity2588 @entity560
CONTEXT: @entity79 ( @entity79 ) is a bone assessment tool that offers information beyond that afforded by dual-energy x-ray absorptiometry (DXA) @entity79 ( @entity79 ) measurements. Adolescents with @entity1278 ( @entity1278 ) are known to exhibit compromised bone density and skeletal strength. OBJECTIVES: This study aimed to determine @entity79 among adolescents with @entity1278 and evaluate the correlation with anthropometric, clinical and densitometric variables. DESIGN: Areal @entity79 spinal measures were analyzed for @entity79 . Findings were compared with clinical (height, weight, body mass index [BMI], age, pubertal development, @entity14257 ) and self-reported data (illness duration, @entity2588 , exercise, @entity174 , family history of @entity170 , and antidepressant use), and @entity79 measures by DXA and peripheral quantitative computed tomography (pQCT). SETTING AND @entity1 : This was an urban adolescent program consisting of 57 females with @entity1278 , age 11-18 y. INTERVENTIONS: Interventions included DXA (absolute @entity79 and Z-score), pQCT (volumetric @entity79 [vBMD] and stress-strain index [SSI]), laboratory evaluation, and questionnaire administration. MAIN OUTCOME MEASURES: Main outcome measures included @entity79 , areal and vBMD, SSI, @entity174 history, disease duration. RESULTS: The @entity79 of six @entity1 (11%) showed degraded and 19 (33%) partially degraded microarchitecture. Spinal @entity79 was correlated (P < .05) with age, height, weight, BMI, pubertal stage, @entity79 , and body composition by DXA, and @entity79 and SSI by pQCT. @entity79 was not correlated with disease duration, @entity174 , @entity560 status, race, or ethnicity, and self-reported health data. CONCLUSIONS: @entity79 showed evidence of degraded microarchitecture in over 40% of this study sample, and strongly correlated with anthropometric data and measures of @entity79 and skeletal strength. @entity79 is a novel tool that captures another dimension of bone health in adolescents with @entity1278 .
