[Influence of plasma replacement on the @entity1578 with XXXX ].

@entity1578 @entity364 @entity281 @entity358 @entity688
OBJECTIVE: To investigate the influence of artificial liver support system on severe @entity1578 with @entity281 , 37 cases of severe @entity1578 and 80 cases times of plasma replacement were analyzed. METHODS: The volume of plasma replacement was 2,000-2,600 ml/time. Japanese Plasauto-iQ Blood Purifying Device was used. Blood samples were observed before and after plasma replacement to determine liver function and prothrombin time. PBMCs were isolated and cultured, and the supernatants were collected to determine the levels of @entity688 ( @entity688 ), IL-12 and gamma-interferon (gamma-IFN). RESULTS: Before plasma replacement, 32 cases of 80 case times had @entity281 , 5 cases of them had fever, the temperature was 37.5-38.0 centigrade. Four cases of them were @entity364 , 1 case was @entity358 . After plasma replacement, liver function was improved, temperature was normal @entity281 was controlled. The levels of @entity688 , IL-12 and gamma-IFN in supernatants before and after plasma replacement were significantly higher than normal control, and the @entity688 level after plasma replacement was markedly higher than that before plasma replacement. The levels of IL-12 and gamma-IFN after plasma replacement were higher than plasma replacement, but they didn't reached statistic difference. CONCLUSION: Plasma replacement might be helpful to control @entity281 and therefore to stabilized the @entity1578 .
