Sequential MR Assessment of the Susceptibility Vessel Sign and Arterial Occlusion in Acute XXXX .

@entity1 @entity64 @entity6520 @entity63
PURPOSE: @entity6520 ( @entity6520 ) may likely influence recanalization after thrombolysis. We assessed, through the European sequential MRI database "I-KNOW," the relationship between the presence of @entity6520 on T2-weighted gradient echo imaging, its angiographic counterpart on magnetic resonance angiography and its subsequent impact on recanalization after thrombolysis. MATERIALS AND METHODS: Initial clinical and MRI characteristics and early follow up were analyzed in acute @entity63 @entity64 @entity1 treated with rt-Pa within 4.5 hours. @entity1 underwent multimodal MRI at admission. Sequential imaging performed 3 hours, 2 days and 1 month later allowed the analysis of @entity6520 changes and recanalization. RESULTS: Fifty @entity1 were included in the study. @entity6520 was observed in 54% of cases at admission. @entity6520 was still present in 46% @entity1 at 3 hours, 16% at 2 days, and 0% at 1 month. It was an independent predictor of no recanalization after thrombolysis (P = .04). After 3 hours, @entity6520 disappeared in only 4 cases, and was not linked with recanalization on MRA. Conversely, when @entity6520 persisted, a partial or complete recanalization was observed in 9 and 6 cases, respectively. CONCLUSIONS: @entity6520 is a predictor of lower recanalization rate. Its disappearance is not necessarily correlated with recanalization.
