[ XXXX in childhood: studies using a molecular biology method (gene electrophoresis)].

@entity1 @entity294 @entity344 @entity6425 @entity5163
During a 15-month period all @entity1 below 16 years admitted to the @entity1 's Hospital in St. Gallen with acute @entity5163 were studied for @entity6425 . Stool samples from control @entity1 without @entity344 were investigated for RV shedding in order to detect RV carriers or asymptomatically infected @entity1 . RV was detected by electrophoresis of RV genomic dsRNA in 154 @entity1 . 119 (58%) of 205 @entity1 hospitalized because of @entity294 were RV associated, 25 @entity1 became symptomatically ill during their hospitalization, and in 10 (1%) of 954 control @entity1 RV could be found. During the winter 1983/1984 two epidemic peaks of RV associated @entity294 were noted, whereas in the summer period RV related disease occurred only sporadically. The peak incidence of @entity6425 was in the age group between 10 and 12 months. After the 3rd year of life @entity6425 only rarely required hospitalization. During this study period 8 different genomic RNA patterns of RV were found. The number of @entity1 within these 8 RV types, however, is too small to allow definite correlations between epidemiological or clinical features and selected electrophorotypes. The possibility to perform refined epidemiological and clinical analyses of @entity6425 by genomic dsRNA electrophoresis offers important advantages when compared to other RV detection systems. In addition, this method has proven to be fast, simple and reliable.
