Primary XXXX . Efficacy of chemo-radiotherapy alone.

@entity1 @entity632 @entity5 @entity900 @entity7297 @entity3 @entity4797
A treatment policy must be established for primary @entity4797 . We have treated five @entity1 with this entity during 18 years. All our @entity1 presented with a bulky mass as is usual for this disease. Our first @entity1 was treated surgically and then with radiation, but developed recurrences and died 11 years after the initial diagnosis. Three subsequent @entity1 , one with multiple lymph node @entity3 , were treated with radiation followed by @entity900 . Our most recent @entity1 received two courses of @entity632 -reinforced PVB, and then radiation for consolidation, followed by another course of chemotherapy. For these five @entity1 , the 5- and 10-year survival rates were both 100%. A review of the literature emphasized the fact that either radiation or surgery has recently been replaced by chemotherapy as the front-line treatment of this rare @entity5 in light of a better response to the latter form of treatment. We fully agree with this policy. Based on the favorable long-term results of our @entity1 we conclude that chemo-radiotherapy can cure primary @entity4797 , even in its extended form, without surgery. An initial three courses of @entity900 -based chemotherapy like @entity632 -reinforced @entity7297 or BEP should be followed by radiation of up to 4,000 cGy for consolidation. Surgery may play a limited role for @entity5 that are small at presentation, or for any possible viable residue seen on roentgenograms following chemo-radiotherapy.
