Effect of a varnish containing XXXX and @entity4745 (Cervitec) on approximal caries in 13- to 16-year-old schoolchildren in a low caries area.

@entity6586 @entity1216 @entity1 @entity4745
BACKGROUND: Previous studies on the effect of the @entity1216 and @entity4745 -containing varnish (Cervitec((R))) have consistently shown a reduction in @entity6586 , while the data on the caries-inhibiting effect are conflicting. AIM: To measure the effect of a @entity1216 - and @entity4745 -containing varnish (Cervitec) on approximal caries in a low caries population. MATERIAL: Eighty-five schoolchildren, 13 years of age, entered the study after being selected on the basis of bitewing radiographs. @entity1 with at least one approximal lesion were included after informed consent. METHODS: The study was carried out as a double-blind, randomized controlled trial according to a split-mouth design using Cervitec on one side and a placebo varnish on the other side. All approximal surfaces between molars and premolars were treated every 3rd month. After 2 years new bitewing radiographs were taken. A total of 73 @entity1 completed the 2-year study. RESULTS: Neither the difference in number of new lesions between the Cervitec-treated and the placebo-treated side (d: -0.21; 95% CI: -0.57; 0.16) nor the mean difference in number of already existing lesions that progressed (d: -0.01; 95% CI: -0.33; 0.30) were statistically significant (paired t test; p > 0.05). CONCLUSION: The results of our study do not indicate an effect of Cervitec on initiation or progression of approximal caries in a population with a low DMFS.
