Association of self-reported physical activity with laboratory markers of nutrition and XXXX : the @entity1650 .

@entity1 @entity32 @entity6 @entity1650 @entity2166 @entity3147 @entity1851
OBJECTIVE: @entity1 on dialysis maintain extremely low levels of physical activity. Prior studies have demonstrated a direct correlation between nutrition and physical activity but provide conflicting data on the link between @entity32 and physical activity. Using a cohort of @entity1 new to dialysis from the @entity1650 ( @entity1650 ), we examined associations of self-reported physical activity with laboratory markers of nutrition and @entity32 . DESIGN, SETTING, AND @entity1 : Between June 2005 and June 2007, @entity1650 collected data on self-reported physical activity, nutrition, and health-related quality of life from @entity1 starting dialysis in 296 facilities located throughout the United States. Baseline serum samples were collected from @entity1 in a nutrition sub-study of @entity1650 . MEASURES: Serum albumin and prealbumin were measured as markers of nutrition, and @entity1851 ( @entity1851 ) and a-1-acid glycoprotein as markers of @entity32 . Self-reported physical activity was characterized by the maximum activity score (MAS) and @entity2166 ( @entity2166 ) of the @entity1 Activity Profile. RESULTS: The mean age of @entity1 in the analytic cohort (n = 201) was 61 years. The MAS and @entity2166 were below the 10th and first percentile, respectively, in comparison with healthy 60 year-old norms. Both activity scores were directly correlated with albumin (r(2) = 0.3, P < .0001) and prealbumin (r(2) = 0.3, P < .0001), and inversely correlated with @entity1851 ( @entity2166 : r(2) = -0.2, P = .01; MAS: r(2) = -0.1, P = .08). In multivariate analyses adjusting for age, gender, race/ethnicity, @entity6 status, and center, both activity scores were directly correlated with prealbumin and inversely correlated with @entity1851 . CONCLUSIONS: @entity1 new to dialysis with laboratory-based evidence of @entity3147 and/or @entity32 are likely to report lower levels of physical activity.
