[Prophylactic antibiotic therapy using XXXX in peripheral vascular surgery of the lower limbs. Preliminary results].

@entity1 @entity3256 @entity86 @entity6101
The rate of @entity86 in lower limb vascular surgery was first evaluated in a retrospective study of 416 bypass procedures (68 venous grafts and 348 prosthetic grafts) in 400 @entity1 seen over a two-year period. 31 @entity86 (7.4%) were found. Outcome was fatal in three cases. 70% of cases were due to a @entity3256 -susceptible Staphylococcus aureus. Antibiotic prophylaxis with @entity6101 given during surgery and for the first 48 postoperative hours was used for the next 112 procedures (17 venous grafts and 95 prosthetic grafts) in 107 @entity1 . The preliminary results show a fall in the rate of @entity86 , with only 5 cases (4.4%). The only case due to a @entity3256 -susceptible Staphylococcus occurred after a second surgical procedure without antibiotic prophylaxis. These preliminary results are promising although the difference does not reach statistical significance. However, it is of note that no @entity1 undergoing vascular surgery for the first time developed @entity86 . Further prospective studies are needed to determine the optimal antibiotic prophylaxis in lower limb vascular surgery.
