Ovarian hormone effects on activity, glucoregulation and thyroid hormones in the XXXX .

@entity172 @entity43 @entity1420 @entity1955 @entity1717 @entity1017 @entity35 @entity1602 @entity413 @entity1954
Ovarian hormonal influences on the range of physiological and behavioral variables which combine to affect overall energy balance are poorly delineated. In the present study 4 groups of virgin, female @entity35 (intact, ovariectomized, ovariectomized with @entity172 replacement and ovariectomized with @entity172 plus @entity1420 ) were allowed access to running wheels and activity; food intake and @entity1017 were measured initially under food restricted, then under ad lib conditions. Serum insulin, @entity413 , @entity1955 (T4) and @entity1954 (T3) were determined on trunk blood samples obtained at the end of the experiment. Ovariectomy resulted in an increased rate of @entity1017 through reduced activity and T3 but food intake was unchanged. Insulin levels were greatly reduced. @entity172 replacement restored activity to the intact group's level and normalized @entity1017 . Insulin and T3 were also raised to control levels but T4 was reduced as was serum @entity413 . @entity172 plus @entity1420 replacement reduced @entity1017 markedly and increased T3 with normal T4. Despite the lower body weight this group was @entity1602 and @entity1717 suggesting insulin resistance. The results have important implications for the glucoregulatory and energy balance perturbations of @entity43 and focus particularly on @entity1420 .
