Early Detection of Subclinical XXXX Using Two-Dimensional Speckle Tracking Echocardiography.

@entity1 @entity8 @entity296 @entity740 @entity1002
BACKGROUND: Overhydration has a deleterious effect on cardio myocytes. This study was designated to evaluate @entity1002 in @entity1 with various stages of @entity740 ( @entity740 ) using conventional, tissue Doppler and two-dimensional speckle tracking echocardiography (2DSTE). METHODS: Forty controls and 90 @entity740 @entity1 , aged 49.3    14 years old, were enrolled in the study. @entity1 were divided into 3 groups depending on their glomerular filtration rate. Group 1 (>= 60 mL/min per 1.73 m(2) ), group 2 ( <=60 mL/min per 1.73 m(2) ), and group 3 ( <=60 mL/min per 1.73 m(2) and on regular dialysis for at least 12 months). Pulsed-Doppler and tissue Doppler studies were used to estimate LV filling pressure E/E'. Using 2DSTE, circumferential, radial, and longitudinal functions of the LV have been measured. RESULTS: @entity1002 , early, and late diastolic strain rates were significantly reduced in @entity740 @entity1 (-16.9    3.8%, 1.6    0.5%, and 1.3    0.4% in @entity740 vs. -22.5    0.6%, 2.3    0.2%, and 1.9    0.1% in controls, P < 0.001 for all), and no difference was observed in terms of the circumferential LV functions (-22.4    1.7 vs. -22.5    1.4, P = 0.567). Severity of the @entity8 appears to parallel with the rise of E/E' significantly (P < 0.001). CONCLUSION: In @entity740 , although the longitudinal and radial systolic functions were reduced, LV ejection fraction may remain within normal limits due to the preservation of the circumferential functions. Early detection of uremic @entity296 might provide useful information for the risk stratification and decide the proper dialysis therapy in these @entity1 .
