Is resection indicated in XXXX deemed curable preoperatively but found to be advanced intraoperatively?

@entity1 @entity5 @entity356
PURPOSE: This study was designed to evaluate the value of resection and to analyze clinicopathologic data on @entity356 @entity1 who were evaluated as curable preoperatively but diagnosed as advanced intraoperatively. METHODS: A retrospective analysis was performed on clinical, surgical, and pathological data of 264 @entity1 who had undergone surgery for @entity356 between January 2008 and October 2012. The @entity1 who were diagnosed in advanced stages during surgical exploration were accepted into the study group. @entity1 were categorized into the following two groups: non-resection group (NRG) and resection group (RG). We compared the clinicopathologic features of the two groups and investigated the prognostic factors by performing univariate and multivariate analyses. RESULTS: A total of 79 @entity1 diagnosed with advanced disease in surgical exploration were evaluated. There were 40 @entity1 (50.6%) in the NRG and 39 @entity1 (49.4%) in the RG. The difference in median overall survival between the NRG and the RG was statistically significant (1.7 vs 5 months; p=0.001). In multivariate analysis, age less than 70 years, gastric resection, adjuvant chemotherapy, and male gender were found to be favorable significant independent prognostic factors for overall survival. Conlusion: Resection seems to be associated with improved overall survival in @entity1 who were diagnosed as advanced intraoperatively. Therefore, @entity1 and @entity5 -related factors should be taken into consideration before planning resection. Randomized controlled studies are required.
