[The assessed value of 64 slice spiral CT perfusion imaging in XXXX after chemotherapy and radiotherapy].

@entity1 @entity957 @entity5
OBJECTIVE: To study the assessed value of 64 slice spiral CT perfusion imaging (CTPI) in @entity957 after chemotherapy and radiotherapy. METHOD: Forty five @entity1 diagnosed with local advanced @entity957 were selected. Conventional CT and CTPI were performed before treatment and at the time of radiation dose up to 40 Gy. Blood flow, blood volume, mean transit time and surface permeability were measured at the same time. According to the decrease of @entity5 volume in final examination, @entity1 were divided into sensitive group and insensitive group. The @entity5 perfusion indexes were compared between groups. RESULT: Blood flow, blood volume, surface permeability after 40Gy treatment were lower than before treatment in both sensitive group and the insensitive group ascended(P<0. 05). The AUC of ROC of blood flow, blood volume, mean transit time and surface permeability were 0. 804, 0. 843, 0. 852 and 0. 826. The sensitivity, specificity and accuracy of blood flow was 89. 7%, 86.8% and 90. 9%. There were 100. 0%, 91. 4% and 93. 7% in blood volume; 100. 0%, 67. 7% and 88. 3% in mean transit time; 91. 2%, 69. 4% and 90. 6% in surface permeability(P<0. 01). CONCLUSION: Sixty-four slice spiral CT perfusion imaging is able to assess @entity5 status of @entity957 after chemotherapy and radiotherapy effectively.
