A Review of Resistance Training-Induced Changes in Skeletal Muscle Protein Synthesis and Their Contribution to XXXX .

@entity1184 @entity2086 @entity3013
UNASSIGNED: Muscle protein synthesis (MPS) is stimulated by resistance exercise (RE) and is further stimulated by protein ingestion. The summation of periods of RE-induced increases in MPS can induce @entity1184 chronically. As such, studying the response of MPS with @entity3013 ( @entity3013 ) is informative, as adaptations in this process can modulate muscle mass gain. Previous studies have shown that the amplitude and duration of increases in MPS after an acute bout of RE are modulated by an individual's training status. Nevertheless, it has been shown that the initial responses of MPS to RE and nutrition are not correlated with subsequent @entity1184 . Thus, early acute responses of MPS in the hours after RE, in an untrained state, do not capture how MPS can affect RE-induced @entity2086 . The purpose of this review is provide an in-depth understanding of the dynamic process of @entity2086 throughout @entity3013 by examining all of the available data on MPS after RE and in different phases of an @entity3013 programme. Analysis of the time course and the overall response of MPS is critical to determine the potential protein accretion after an RE bout. Exercise-induced increases in MPS are shorter lived and peak earlier in the trained state than in the untrained state, resulting in a smaller overall muscle protein synthetic response in the trained state. Thus, @entity3013 induces a dampening of the MPS response, potentially limiting protein accretion, but when this occurs remains unknown.
