Overexpression of interleukins @entity4155 and XXXX with poor prognosis in @entity14 induces @entity3 .

@entity1 @entity5 @entity189 @entity4155 @entity3 @entity14 @entity687
UNASSIGNED: Current evidences indicated that a group of soluble mediators called chemokines is involved in @entity5 growth and @entity3 . The association of @entity687 with @entity5 cell migration was previously found, and its expression was related to angiogenesis, @entity5 progression, and @entity3 in many kinds of @entity189 in @entity1 and animal models. Furthermore, it has been showed that @entity4155 plays its role as either a proteome of @entity5 progression or antitumor indifferent @entity5 models. To investigate the messenger RNA (mRNA) expressions of @entity687 and @entity4155 in @entity1 with @entity14 ( @entity14 ) and non- @entity5 tissue, quantitative real-time PCR was used in the study. Our results showed that expression of @entity687 mRNA was significantly increased in @entity5 tissues (mean        SD 3.84        0.08) compared with adjacent normal mucosa (mean        SD 1.17        0.75, P   =   0.001). Furthermore, a higher expression of @entity4155 mRNA was found in @entity5 tissues (mean        SD 2.73        0.69) when compared with normal tissues (mean        SD 1.06        0.07, P   =   0.001). Our findings indicated that advanced @entity5 ( @entity5 ) stage (P   =   0.024) and histological grade (poorly differentiated, P   =   0.013) and distant @entity3 (P   =   0.001) were correlated with expression of @entity687 . Moreover, high expression of @entity4155 showed significant association with early stage @entity14 ( @entity5 ) (P   =   0.038). In conclusion, the expression of @entity687 and @entity4155 mRNAs was significantly increased in @entity5 tissues compared with adjacent normal tissues. We found that advanced @entity5 stage and histological grade and distant @entity3 were correlated with expression of @entity687 , while high expression of @entity4155 showed significant association with early stage @entity14 ( @entity5 ) stage and overexpression of @entity687 may be associated with progression of @entity14 .
