Baseline B-type natriuretic peptide: a gender-specific predictor of procedure-outcome in XXXX @entity1 undergoing catheter ablation.

@entity1 @entity591 @entity3876 @entity955
BACKGROUND: Close association between @entity955 ( @entity955 ) and @entity3876 ( @entity3876 ) has been demonstrated by several studies. Important gender differences exist in @entity955 @entity1 including a higher plasma @entity3876 level in @entity1 . Therefore, it is imperative to evaluate the relationship between @entity955 and @entity3876 separately in @entity1 and @entity1 . OBJECTIVE: This study examined possible gender-specific role of @entity3876 in predicting procedure outcome in @entity955 @entity1 undergoing catheter ablation. METHOD: The study population included 568 consecutive @entity1 (age 62    10, male 73%, paroxysmal 25%, persistent 38%, and long-standing persistent @entity955 37%) undergoing @entity955 ablation, who had structurally normal heart and left ventricular ejection fraction >= 45%. Baseline @entity3876 was measured in all. @entity1 were grouped into "normal" and "high" @entity3876 based on gender-specific cut-off values (<50 and >= 50 pg/mL in males, <100 and >=  100 pg/mL in females). RESULT: Baseline @entity3876 was significantly higher among @entity1 than @entity1 (126    112 versus 87    99, P = 0.009). At 12    6 month follow-up, 304 of 414 (73%) males and 98 of 154 (64%) females were @entity955 / @entity591 -free off antiarrhythmic drugs (log-rank P = 0.018). In multivariable analysis, @entity3876 remained an independent predictor of @entity955 recurrence ( @entity3876 >=  50: hazard ratio [HR] 2.54, P = 0.006) in males. No such association was observed among females ( @entity3876 >=  100: HR 0.79, 95% CI 0.43-1.42; P = 0.426). CONCLUSION: Baseline @entity3876 was found to be an independent predictor of @entity955 recurrence in male @entity1 undergoing ablation. This correlation between @entity3876 and @entity955 recurrence was not observed in females. Thus, @entity3876 plays a gender-specific prognostic role in @entity955 .
