Early Anatomical @entity302 in Head Cooled Neonates With XXXX .

@entity1 @entity1545 @entity410 @entity2806 @entity739 @entity302 @entity62 @entity130
BACKGROUND: Our aim was to determine whether early anatomical injury patterns on magnetic resonance imaging-correlate with the development of @entity302 in @entity1 treated with selective head cooling for @entity2806 . METHODS: We retrospectively analyzed @entity1 >= 35  weeks' gestation born between 2008 and 2013 and followed for at least one year at Northwestern University. All had brain magnetic resonance imaging scans at days 4-5 and electroencephalographs during rewarming and at 3 to 6  months of age. RESULTS: Outcome was favorable for our cohort of 73 individuals with a mean follow-up of 41 (  7) months. The majority (66%) survived with no @entity410 recurrence, whereas 13 (18%) developed @entity302 , including eight who had @entity739 . Twelve @entity1 (16%) died. The most common magnetic resonance imaging pattern was @entity1545 involving both cortical and subcortical gray matter (26/73, 35%), followed by @entity62 (18/73, 25%) and normal magnetic resonance imaging (16/73, 22%). In 13 @entity1 (18%), the brainstem was involved in addition to cortical and subcortical gray matter; nine died and all four surviving @entity1 developed @entity739 . All 18 @entity1 with @entity62 survived and none developed @entity302 . The risk of @entity302 was associated with @entity130 (basal ganglia, thalamus      brainstem) (12/39 versus 1/34, P  <  0.003). CONCLUSIONS: @entity130 was highly predictive of @entity739 , whereas @entity130 alone predicted low risk for short-term @entity302 . Location of anatomical injury on magnetic resonance imaging can be an early predictive factor for development of @entity739 and inform prognostic decisions in newborns treated with selective head cooling for @entity2806 .
