The diagnostic accuracy of routine electroencephalography after a first unprovoked XXXX .

@entity1 @entity410 @entity302
UNASSIGNED: The clinical utility of routine electroencephalography (EEG) after a first unprovoked @entity410 remains uncertain. Its diagnostic accuracy in identifying adults and @entity1 with new onset @entity302 was examined. A systematic review and meta-analysis of studies examining individuals who underwent routine EEG after a first unprovoked @entity410 and were followed for @entity410 recurrence for at least 1  year was performed. A 'positive' test was defined by the presence of @entity302 ( @entity302 ). Pooled sensitivity and specificity estimates were calculated using a bivariate random effects regression model. In all, 3096 records were reviewed, from which 15 studies were extracted with a total of 1799 @entity1 . Amongst adult studies, the sensitivity and specificity (95% confidence interval) of routine EEG were 17.3% (7.9, 33.8) and 94.7% (73.7, 99.1), respectively. Amongst @entity1 studies, the pooled sensitivity and specificity were 57.8% (49.7, 65.6) and 69.6% (57.5, 79.5), respectively. Based upon our positive likelihood ratios, and assuming a pre-test probability of 50%, an adult with @entity302 on routine EEG after a first unprovoked @entity410 has a 77% probability of having a second @entity410 , whilst a @entity1 with similar findings has a 66% probability. Further studies are required to examine the impact of @entity1 characteristics and EEG features on the diagnostic accuracy of routine EEG for new onset @entity302 .
