Postingestional modulation of drinking induced in XXXX by @entity1808 : intragastric infusion and sham drinking studies.

@entity1219 @entity1808 @entity292 @entity11541 @entity35
The dipsogenic potency of @entity1808 ( @entity1808 , 200 micrograms/kg, SC) was examined after the removal of various postingestional factors. In the first experiment, @entity35 with intragastric catheters were injected SC with @entity1808 and allowed water to drink. During the induced drinking, either @entity1219 (1.5 M) or water was injected into the stomach via the catheter at a rate of 0.1 ml for each ml water ingested orally. The water intake was identical in the two conditions. In a second experiment, @entity35 , fitted with @entity11541 , were administered @entity1808 and subsequent water intake with @entity292 open was compared to that occurring with the @entity292 closed. @entity35 drank more water during the first trial with @entity292 open than with @entity292 closed. Water intake during subsequent trials with an open @entity292 rose above that observed on the first trial. In a third experiment, @entity35 with @entity11541 were offered 0.15 M @entity1219 to drink. Intake was greater when the @entity292 was open than when it was closed. Intake of 0.15 M @entity1219 increased during the second trial with @entity292 open. @entity35 drank more 0.15 M @entity1219 during the first trial with an open @entity292 in Experiment 3 than those @entity35 given water to drink on their first trial with @entity292 open in Experiment 2. These data suggest both oropharyngeal and postingestional factors interact in the control of @entity1808 -induced fluid intake.
