Identification of thyroid hormone receptors in the XXXX larynx.

@entity1 @entity1375 @entity406 @entity11112 @entity982 @entity22910 @entity1374
PURPOSE: Thyroid hormone is essential for normal development, growth, and function of the majority of tissues. Among the many clinical signs associated with @entity1375 , alterations in the voice may occur even in cases of mild @entity1374 , suggesting that the larynx is a target tissue for thyroid hormone. The objective of our study is to further understand the effects of thyroid hormone on the larynx by first identifying the presence and locations of its receptors. METHODS: Two @entity1 cadaveric larynges (one male and one female) were harvested, @entity406 -fixed, and @entity982 -embedded. Sections were immunostained with antibodies reactive with the two identified thyroid hormone receptors, @entity22910 and @entity11112 . The slides were examined under light microscopy. RESULTS: Both male and female specimens revealed consistent patterns of staining for thyroid hormone receptors. The staining pattern for @entity22910 included the fibrous connective tissue of the lamina propria, the cartilage, and the glandular elements. The staining pattern for @entity11112 included the fibrous connective tissue of the lamina propria only. No receptors were identified in the respiratory mucosa or muscle. CONCLUSIONS: Thyroid hormone receptors are present in both the male and the female @entity1 larynx. These findings imply a role for thyroid hormone within the @entity1 larynx, through both @entity22910 and @entity11112 .
