Effects of fetal behavioral states on renal sympathetic nerve activity and arterial pressure of unanesthetized fetal XXXX .

@entity551 @entity742 @entity1353
Fetal behavior, renal sympathetic nerve activity (RSNA), mean arterial pressure (MAP), and heart rate (HR) were studied 1-3 days after surgery in seven fetal @entity742 (aged 127-136 days). Five behavioral states were defined from chart recordings of electrocortical (electrocorticographic; ECoG) activity and eye, limb, and @entity1353 movements. Most records were of high-voltage ECoG (HV) or low-voltage (LV) ECoG with @entity1353 (LVB); 6.7 +/- 1.7% were LV ECoG with no @entity1353 (LV0). RSNA was lower in LV0 (P < 0.001) and greater in LVB than in HV (P < 0.05). MAP was lower in both LV states than in HV and when the fetuses went from LV to HV (P < 0.001 to P < 0.03). HR was highest in HV (P < 0.001). In HV and LVB and when the fetus went from @entity551 were inversely related (P = 0.012-0.003). In LVB and from LV to HV there were direct relationships between MAP and RSNA (P = 0.0014, P = 0.08), and when the fetus went from LV to HV there was also an inverse relationship between HR and RSNA (P = 0.02). Thus fetal RSNA, MAP, and HR are affected by behavioral state as is fetal cardiovascular control. The increase in RSNA during fetal @entity1353 showed that there was an altered level of fetal RSNA associated with fetal @entity1353 activity.
