XXXX : a single hospital-based study in a 24-year period.

@entity1 @entity370 @entity358
BACKGROUND: Clinical presentation of @entity370 varies according to race and geographical area. We describe the clinical spectrum and outcome of @entity370 in Mexican @entity1 compared with other populations. METHODS: We reviewed the medical charts of 21 @entity1 with @entity370 seen at a referral hospital in 1989-2012; organ involvement was assessed using the ACCESS instrument. We compared our results with the ACCESS and Latin American studies. We used descriptive statistics and reported odd ratios with 95% CI. RESULTS AND CONCLUSION: Fifty-two percent were @entity1 ; median age was 31 years; median time to diagnosis, 5.5 months. Frequency of organ involvement was: constitutional symptoms 62%, lungs 66.6%, skin 42.8%, bone marrow 23.4%, lymph node 19%, liver 19%, and eye 19%. After one year of follow-up, 47.5% of @entity1 were asymptomatic without treatment, 38% asymptomatic on treatment, and 14.2% symptomatic on treatment. In our @entity1 , @entity358 was lower (66.6 vs. 94.9%; p = 0.001) and cutaneous (42.8 vs. 15.8%; p = 0.003) and bone marrow (23.4 vs. 4.7%; p = 0.001) were higher than in the ACCESS cohort. Data regarding Latin American populations was scarce. The clinical spectrum of @entity370 in our population differed from other studies, with a higher frequency of @entity370 and less @entity358 .
