Influence of @entity35695 haplotype on ovulation rate and litter size in miniature XXXX .

@entity1707 @entity1420 @entity53 @entity35695 @entity7042
Systemic blood was collected from and surgery performed on sows of 3 strains of miniature @entity1707 bred for specific @entity35695 ( @entity1707 MHC) haplotypes (a, c and d) from Day 2 to Day 6 after mating (first day of mating = Day 0). Ovulation rate was determined by counting corpora lutea and embryos were flushed from the uterus. @entity1420 , @entity53 -17 beta and @entity7042 were quantitated in blood plasma and uterine flushings by RIA. SLAd/d females had a higher ovulation rate than SLAa/a or SLAc/c females (11.50 +/- 0.87 vs 9.11 +/- 0.68 and 8.17 +/- 0.83, respectively; P less than 0.01). @entity7042 was higher than @entity53 -17 beta in systemic plasma (56.5 +/- 6.4 vs 33.0 +/- 4.7 pg/ml, P less than 0.01) while @entity53 -17 beta was higher than @entity7042 in uterine flushings (19.8 +/- 1.4 vs 14.9 +/- 1.5 pg/horn, P less than 0.10). Systemic @entity1420 concentration was correlated with day after mating (r = 0.93, P less than 0.01). There was no effect of haplotype on any of the hormone concentrations measured. Litter size was analysed from 99 matings amongst SLAa/a, SLAa/c, SLAa/d, SLAd/c and SLAd/d sires and dams. Litter size from -/d and d/d sows or from d/d boars were larger (P less than 0.05) than for all other matings. Although ovulation rate was higher in SLAd/d sows, the significant effect of sire @entity35695 genotype on litter size suggests an additional effect of the d haplotype on embryonic survival.
