Increased arterial compliance in XXXX is related to decreased arterial @entity21695 , but not to atrial natriuretic peptide.

@entity1 @entity82 @entity21695 @entity101 @entity1457 @entity1442
BACKGROUND: Increased arterial compliance (COMPart) has recently been described in @entity1 with @entity82 , particularly in @entity1442 . The aim of the present study was to relate COMPart with arterial levels of the circulating natriuretic peptides: atrial natriuretic peptide (ANP) and @entity21695 ( @entity21695 ), both of which are vasodilators. METHODS: Thirty-one @entity1 with @entity82 , 14 non-cirrhotic @entity1 with circulatory disturbances of the ischaemic and @entity101 type, and 10 healthy controls were investigated during a haemodynamic examination. RESULTS: The @entity1 with @entity82 showed the well-known hyperdynamic circulation with elevated cardiac output, low arterial blood pressure, and reduced systemic vascular resistance. COMPart in the @entity1 with @entity82 (1.30 mL/mmHg) was significantly (P < 0.01) increased compared to that of non-cirrhotic @entity1 (0.99 mL/mmHg) and controls (1.01 mL/mmHg). In the @entity1 with @entity82 , a significant inverse correlation was found between @entity21695 and COMPart (r = -0.42, P < 0.01), but not between @entity21695 and systemic vascular resistance (r = 0.31, P = 0.08). In the non-cirrhotic @entity1 , @entity21695 had a significant inverse correlation to COMPart (r = -0.68, P < 0.01) and a direct correlation to systemic vascular resistance (r = 0.62, P < 0.02). ANP was not significantly related to COMPart nor to systemic vascular resistance in any of the groups. CONCLUSION: The finding of an inverse relation between @entity21695 and COMPart may suggest that a compensatory down-regulation of @entity21695 occurs in @entity1 with @entity82 and other types of @entity1457 when vasodilation persists. Regulation of large and small arteries by @entity21695 may be different in @entity82 . Arterial ANP is not related to properties of the large or small arteries.
