Controlled Study of Obesity Among Adolescents with XXXX .

@entity1 @entity162 @entity28 @entity146 @entity1316 @entity161 @entity952 @entity750
OBJECTIVE: Despite numerous studies regarding @entity28 ( @entity28 ) in adult @entity162 ( @entity162 ), there are few studies on this topic among adolescents. The current study attempts to extend the literature on prevalence and correlates of @entity28 in adolescent @entity162 by including control @entity1 , and determining @entity28 by direct measurement. METHODS: @entity1 were 75 treatment-seeking adolescents, ages 13-19 years, with @entity162 -I, -II, or -not otherwise specified, and 47 adolescents without major @entity146 . Diagnoses and clinical characteristics were assessed using the Kiddie Schedule for @entity1316 and @entity161 for School Age @entity1 , Present and Lifetime version (KSADS-PL). Family @entity146 history was assessed using the Family History Screen. @entity28 was defined as adjusted body-mass index >= 95th percentile. Variables associated with @entity28 in univariate analyses informed variable selection for within-group logistic regression analysis among @entity162 adolescents. RESULTS: @entity162 @entity1 had a significantly higher rate of @entity28 (18%) compared to controls (4%;   (2)   =   5.3; p   =   0.02). @entity162 remained a significant predictor for @entity28 when controlling for race (odds ratio [OR]   =   5.1, 95% confidence interval [CI]   =   1.1-24.0, p   =   0.04). In univariate analyses among @entity162 adolescents, @entity28 was significantly associated with suicide attempt, self-injurious behavior, and @entity952 . In multivariable analyses, suicide attempt and antidepressants that were not selective @entity750 reuptake inhibitors were significantly associated with @entity28 . CONCLUSIONS: @entity28 is excessively prevalent among adolescents with @entity162 and is associated with proxies for illness severity, including suicide attempts. Additional research is warranted to identify strategies to prevent and treat @entity28 among @entity162 adolescents, and to elucidate processes underlying the elevated risk of suicide attempts.
