YOCAS     Yoga Reduces Self-reported Memory Difficulty in XXXX Survivors in a Nationwide Randomized Clinical Trial: Investigating Relationships Between Memory and Sleep.

@entity5 @entity1 @entity601 @entity3628
BACKGROUND: Interventions are needed to alleviate memory difficulty in @entity5 survivors. We previously showed in a phase III randomized clinical trial that YOCAS     yoga-a program that consists of breathing exercises, postures, and meditation-significantly improved sleep quality in @entity5 survivors. This study assessed the effects of YOCAS     on memory and identified relationships between memory and sleep. STUDY DESIGN AND METHODS: Survivors were randomized to standard care (SC) or SC with YOCAS     . 328 @entity1 who provided data on the memory difficulty item of the @entity601 Anderson Symptom Inventory are included. Sleep quality was measured using the Pittsburgh Sleep Quality Index. @entity3628 ( @entity3628 ) determined the group effect of YOCAS     on memory difficulty compared with SC. @entity3628 also determined moderation of baseline memory difficulty on postintervention sleep and vice versa. Path modeling assessed the mediating effects of changes in memory difficulty on YOCAS     changes in sleep and vice versa. RESULTS: YOCAS     significantly reduced memory difficulty at postintervention compared with SC (mean change: yoga=-0.60; SC=-0.16; P<.05). Baseline memory difficulty did not moderate the effects of postintervention sleep quality in YOCAS     compared with SC. Baseline sleep quality did moderate the effects of postintervention memory difficulty in YOCAS     compared with SC (P<.05). Changes in sleep quality was a significant mediator of reduced memory difficulty in YOCAS     compared with SC (P<.05); however, changes in memory difficulty did not significantly mediate improved sleep quality in YOCAS     compared with SC. CONCLUSIONS: In this large nationwide trial, YOCAS     yoga significantly reduced @entity1 -reported memory difficulty in @entity5 survivors.
