Prevalence and XXXX of intracranial arterial stenotic lesions as assessed with multidetector computed tomography angiography.

@entity1 @entity64 @entity63 @entity7244 @entity730 @entity4522 @entity385
BACKGROUND AND PURPOSE: @entity7244 ( @entity7244 ) in @entity1 with recent @entity385 is associated with a high risk of recurrent @entity64 . More insight into the pathophysiology of @entity7244 could help identify @entity1 at high risk requiring more aggressive secondary prevention. We evaluated the prevalence, distribution, @entity730 , and the risk factors predisposing @entity7244 in a @entity64 population. METHODS: Consecutive @entity1 with a transient @entity63 attack or @entity385 (n=786) were evaluated for the presence and distribution of @entity7244 (>= 30% luminal narrowing) by CT angiography. @entity7244 were categorized as symptomatic or asymptomatic, and the presence of @entity730 was assessed. The association of traditional cerebrovascular risk factors and the erythrocyte sedimentation rate with @entity7244 was analyzed. RESULTS: In 178 of 786 @entity1 (23%), 288 @entity7244 were observed. Most stenoses (n=194/288; 67%) were located in the posterior circulation arteries. In 59 of 786 @entity1 (8%), @entity7244 were considered symptomatic. @entity7244 in the basilar artery and arteries beyond the circle of Willis were mainly noncalcified. In addition to age, gender, and several traditional cerebrovascular risk factors, erythrocyte sedimentation rate was independently associated with the presence of @entity7244 (OR, 1.20; 95% CI, 1.06-1.36) and with the presence of noncalcified @entity7244 in particular (OR, 1.20; 95% CI, 1.05-1.37). CONCLUSIONS: @entity7244 was observed in a noteworthy number of @entity64 @entity1 . Particularly, the majority of @entity7244 was observed in the posterior circulation, possibly conferring worse prognosis. @entity7244 in distal arteries were mainly noncalcified. Association of noncalcified @entity7244 and erythrocyte sedimentation rate may indicate a prominent role for inflammatory factors in @entity4522 .
