The Impact of Exercising During Haemodialysis on Blood Pressure, Markers of XXXX and Systemic Inflammation - Preliminary Results of a Pilot Study.

@entity1 @entity32 @entity650 @entity310 @entity6949 @entity1193 @entity1200 @entity299 @entity65
BACKGROUND/AIMS: @entity1 requiring haemodialysis have @entity65 . Little is known about the acute effects of exercise during haemodialysis. Exercise has numerous health benefits but in other populations has a profound impact upon blood pressure, @entity32 and immune function; therefore having the potential to exacerbate @entity65 in this vulnerable population. METHODS: Fifteen @entity1 took part in a randomised-crossover study investigating the effect of a 30-min bout of exercise during haemodialysis compared to resting haemodialysis. We assessed blood pressure, plasma markers of @entity299 and systemic @entity32 and neutrophil degranulation. RESULTS: Exercise increased blood pressure immediately post-exercise; however, 1 hour after exercise blood pressure was lower than resting levels (106  22 vs. 117  25 mm Hg). No differences in h-FABP, @entity6949 , myoglobin or CKMB were observed between trial arms. Exercise did not alter circulating concentrations of @entity650 , @entity310 or @entity1193 nor clearly suppress neutrophil function. CONCLUSIONS: This study demonstrates fluctuations in blood pressure during haemodialysis in response to exercise. However, since the fall in blood pressure occurred without evidence of @entity299 , we regard it as a normal response to exercise superimposed onto the haemodynamic response to haemodialysis. Importantly, exercise did not exacerbate systemic @entity32 or @entity1200 ; intradialytic exercise was well tolerated.
