Risk factors of morbidity and predictors of long-term survival after hepatopancreatoduodenectomy for XXXX .

@entity1 @entity788 @entity5 @entity648 @entity1126 @entity3 @entity1125
BACKGROUND/AIMS: Hepatopancreatoduodenectomy (HPD) is performed to achieve radical resection of @entity5 . We reviewed clinical outcomes to evaluate the utility of HPD in terms of morbidity and mortality. METHODOLOGY: A retrospective analysis was conducted on 17 @entity1 underwent HPD between August 1991 and May 2013; 9 @entity1126 , 5 advanced gallbladder and 3 @entity788 with liver @entity3 . RESULTS: The morbidity and mortality rates were 88.3% and 0%, respectively. Univariate analysis showed that a body mass index of >= 22 and preoperative total @entity648 level >= 0.8 mg/dl were significantly associated with severe complications. One-, 3- and 5-year survival rate were 73.3%, 60.0% and 30.0%. In 14 @entity1 with @entity1125 , univariate analysis showed that a histological grade of G1 was significantly associated with survival. @entity1 without pancreatic invasion or portal vein invasion tended to survive longer than @entity1 with these types of invasion, although the difference was not significant. CONCLUSIONS: HPD can be performed with no mortality and provides a survival benefit for some @entity1 with @entity1125 undergoing curative resection. In @entity1 with grade G1 @entity1125 without @entity788 in particular, this aggressive surgery might offer a chance of long-term survival.
