A simple, innovative way to reduce XXXX symptoms after sedation during endoscopy.

@entity1 @entity26 @entity680 @entity2490 @entity5254 @entity519 @entity1875 @entity1363 @entity26920
BACKGROUND: Supplmental @entity26 is routinely given via nasal cannula (NC) to @entity1 undergoing moderate sedation for endoscopy. Some @entity1 complain of profuse @entity5254 and   or sneezing after the procedure, which results in additional medical costs and @entity1 dissatisfaction. OBJECTIVES: To determine the causal relationship between the route of @entity26 delivery and troublesome nasal symptoms, and to seek possible solutions. METHODS: @entity1 (n=836) were randomly assigned to one of the three following groups: the NC group (n=294), the trimmed NC (TNC) group (n=268) and the @entity26920 ( @entity26920 ) group (n=274). All received @entity680 12.5  g   kg and @entity1363 0.06 mg   kg, and adjunct @entity1875 for sedation. Supplemental @entity26 at a flow rate of 4 L   min was used in the NC and TNC groups, and 6 L   min in the @entity26920 group. The incidence of nasal symptoms and @entity519 were assessed. RESULTS: The incidence of @entity2490 symptoms was significantly higher in the NC group (7.1%) than in the TNC (0.4%) and @entity26920 (0%) groups (P<0.001). The incidence of @entity519 was lower in the NC group (3.1%) (P=0.040). All @entity519 events were transient (ie, less than 30 s in duration). On spirometry, the mean value of the lowest saturation of peripheral @entity26 was found to be significantly lower in the @entity26920 group (96.8%) than in the NC group (97.7%) (P=0.004). CONCLUSIONS: Trimming the NC or using NMs reduced the incidence of @entity2490 symptoms; however, the incidence of @entity519 was higher. Further investigation regarding the efficiency of @entity26 supplementation is warranted in the design of novel @entity26 delivery devices.
