Quantitative sensory testing profiles in @entity615 are distinct from those in XXXX .

@entity1 @entity239 @entity615 @entity23 @entity158 @entity9
OBJECTIVES: Alterations in the central nervous system leading to higher @entity158 sensitivity have been shown in both @entity615 ( @entity615 ) and @entity239 ( @entity239 ). The aim of this study was to disclose commonalities and differences in the pathophysiology of @entity239 and @entity615 . METHODS: We used the quantitative sensory testing protocol of the German Research Network on @entity9 to obtain comprehensive profiles of somatosensory functions. The protocol comprised thermal and mechanical detection and @entity158 thresholds, vibration thresholds, and @entity158 sensitivity to sharp and blunt mechanical stimuli. We studied 21 @entity239 @entity1 (mean @entity158 duration: 13.4 y), 23 @entity615 subjects (mean @entity158 duration: 15.9 y), and 20 @entity23 ( @entity23 ). Each @entity1 received the test battery on the back and on the dorsal hand ( @entity158 -free control site). RESULTS: On the back, @entity239 @entity1 showed increased thermal and mechanical @entity158 sensitivity compared with @entity23 and @entity615 @entity1 . On the hand dorsum, @entity239 @entity1 showed higher mechanical @entity158 sensitivity compared with @entity615 @entity1 and @entity23 and higher cold @entity158 sensitivity compared with @entity23 . @entity615 @entity1 showed increased @entity158 sensitivity and lower vibration sensitivity on the back, but no significant differences on the hand dorsum compared with @entity23 . DISCUSSION: @entity239 @entity1 showed increased sensitivity for different @entity158 modalities at all measured body areas, suggesting central disinhibition as a potential mechanism. @entity615 @entity1 in contrast, showed localized alterations within the affected segment possibly due to peripheral sensitization.
