Sublingual vs. Oral XXXX in @entity101 Crisis.

@entity1 @entity20805 @entity101 @entity23380 @entity551
BACKGROUND: There are confusing data in literature regarding oral and sublingual @entity20805 effects over blood pressure (BP) decrease. OBJECTIVES: In our study we compared oral and sublingual @entity20805 effectiveness over BP decrease in @entity1 admitted to our Emergency Department with @entity101 urgency. METHODS: Our study was conducted from January 2012 to January 2013 in @entity1 with @entity101 urgency. In this cross-sectional study after two initial BP measurements, @entity1 were identified as eligible for the study. An initial electrocardiogram was obtained and blood samples were drawn. A total of 212 @entity1 were accepted as eligible for the study, and 25  mg of @entity20805 was randomly given orally or sublingually; BP was measured at 10, 30, and 60  min. We selected the @entity1 to the groups consecutively. A 25% reduction of initial @entity23380  h after initiation of the treatment was accepted as an accomplishment. A second 25  mg of @entity20805 was given if the target of 25% reduction of BP was not reached after the first tablet. Intravenous drugs were administered to the @entity1 resistant to the @entity20805 and these @entity1 were excluded from the study. RESULTS: The 10-min systolic BP (SBP), diastolic BP, and @entity551 ( @entity551 ) decrease was more prominent in the sublingual @entity20805 group (p  <  0.001). This decrease was statistically significant in the SBP and @entity551 at 30  min (p  <  0.001), and no statistical difference was recorded at 60  min (p  >  0.05). CONCLUSIONS: In our study, sublingual @entity20805 was found to decrease BP more efficiently in the first 30  min, but this difference equalized at 60  min.
