Treatment of Recurrent XXXX by Intravesical Instillations of Hyaluronic Acid.

@entity1 @entity281 @entity2335 @entity7245
PURPOSE: To evaluate the results of intravesical instillations of @entity7245 ( @entity7245 ) in the treatment of @entity2335 ( @entity2335 ), and to assess the rate of tolerability, the rate of recurrence of @entity2335 and side effects of treatment. MATERIALS AND METHODS: The study included 23 female @entity1 from September 2012 to May 2013, aged 28-42 years. Twenty three @entity1 with a history of @entity2335 , received intravesical instillations of @entity7245 once weekly for 6 weeks then once monthly for 8 months. RESULTS: In 16 (69.6%) of @entity1 , symptoms of @entity2335 resolved after 8 months. In 5 (21.7%) @entity1 after 8 months of @entity7245 treatment, urgency was reduced only by 30%. Therefore, it was decided to use combined therapy of @entity7245 and alpha blockers in this cohort group. There was a specific reduction (75%) in frequent urination at day and at night without urgency. Despite the use of above mentioned treatment, in 2 (8.7%) @entity1 , @entity2335 was still present and therefore the treatment was discontinued. CONCLUSION: The use of @entity7245 protects mucosa of urinary bladder and alleviates symptoms of @entity281 . The intra_vesical instillations of @entity7245 and combination of @entity7245 + alpha blockers seems to be an effective therapeutic alternative in @entity1 with @entity2335 ._nbsp.
