Imaging characteristics of XXXX .

@entity1 @entity1143 @entity8 @entity932 @entity174 @entity9058 @entity75 @entity5 @entity649 @entity828 @entity74 @entity130
BACKGROUND: @entity9058 ( @entity9058 ) is a @entity74 of immune regulation, with overproduction of cytokines and diminished immune surveillance. Symptoms are nonspecific and may affect multiple organs, including the central nervous system. Neuroimaging findings have been described in case reports and small series; body imaging findings have not been described extensively. OBJECTIVE. To summarize findings of the most frequently performed imaging studies of the brain, chest and abdomen in @entity1 with @entity9058 . MATERIALS AND METHODS: Retrospective review of chest radiographs and CT, abdominal ultrasound and CT, brain CT and MRI, skeletal surveys, and autopsy data. RESULTS: Twenty-five @entity1 were diagnosed and treated for @entity9058 at our institution over an 11-year period; 15 @entity1 (60%) died. Common chest radiograph findings included alveolar-interstitial opacities with @entity1143 , often with rapid evolution and resolution. @entity828 , gallbladder wall thickening, @entity8 were common abdominal findings, which resolved after therapy in some cases. Brain-imaging studies revealed nonspecific periventricular white-matter abnormalities, @entity75 and enlargement of extra-axial fluid spaces. Three @entity1 cases, one with @entity932 , one with multiple pathologic @entity174 and one with diaphyseal periosteal reaction involving multiple long bones on skeletal survey, raised suspicion of @entity1 abuse at presentation. Abuse was not substantiated in any case. CONCLUSIONS: Clinicians and radiologists should be aware of the radiographic manifestations of @entity9058 , which are nonspecific and overlap with infectious, inflammatory and @entity5 . Findings in the chest (similar to acute @entity649 ) and abdomen may progress rapidly and then regress with institution of appropriate anti- @entity9058 therapy. CNS findings may be progressive. In some @entity1 , initial imaging findings may mimic nonaccidental @entity130 .
