Clinicopathologica Epidemiological Characteristics and Change XXXX in Shanxi Province of China from 2005 to 2014.

@entity1 @entity8 @entity5 @entity1358 @entity3
OBJECTIVES: @entity1358 is the most common solid @entity8 in adults worldwide. To provide the insight of clinicopathologica epidemiological characteristics and change tendencies of @entity1358 ( @entity1358 ), 2154 cases were collected from Shanxi Province of China, including diagnose time, age, gender, @entity5 size, Fuhrman grade, @entity5 stage, @entity5 location, local advance or distant @entity3 and first symptom from 2005 to 2014. This retrospectively investigation, as its general objective, was to analyze the clinicopathologica epidemiological characteristics and the change tendencies of @entity1358 . METHODS: Between 2005 and 2014, 2154 @entity1 who were diagnosed with @entity1358 in three large tertiary hospitals at Shanxi Province were included. The @entity1 ' demographic features, pathological diagnoses and metastatic statuses were analyzed. Statistics methods include the chi-squared test, analysis of variance, Spearman's correlation analysis, Logistic regression and ARIMA modeling. RESULTS: Of the 2154 included @entity1 , the constituent ratio of female /male was 63.1% and 36.9%, with the median age of 57 years old. Fuhrman grade distributions differed significantly between males and females (p = 0.024). Also, a significant difference in @entity5 size was found by different clinical stages (p < 0.001), with a linear correlation (p < 0.001). Moreover, Spearman's analysis indicated @entity5 grade has a negative correlation with female (p = 0.009) and a positive correlation with @entity5 size (p = 0.000). It was found that the @entity5 diameter is bigger in the left side (p = 0.022). Furthermore, the @entity3 rate was higher in the bigger @entity5 (p < 0.001) and the left-sided @entity5 (p = 0.027). Logistic regression also showed that @entity5 size is a risk factor for @entity3 (OR = 1.724). The risk of local advance or distant @entity3 in the left kidney was 1.6-fold greater than that of the right kidney. From 2005 to 2014 the number of @entity1358 cases gradually increased (mainly for pathological grade II and III, but grade I and IV), while the average @entity5 size decreased, showing the severity increase mildly. Base on the results of a time series analysis-prediction the average @entity1358 size would continue to decrease from the first quarter of 2015 to the fourth quarter of 2016. CONCLUSIONS: The cases of @entity1358 increased from 2005 to 2014 with clear cell type as the main pathological type in this population. The characteristics in the constituent ratios of the @entity1358 vary depending on gender, pathological grade, @entity5 size, and location, which may be the important factors impacting treatment and prognosis.
