Prenatal diagnoses and outcomes of XXXX .

@entity2914 @entity1 @entity2978
OBJECTIVE: To describe the prenatal diagnoses and clinical outcomes of @entity2914 ( @entity2914 ). METHODS: A retrospective case series was developed by reviewing 16,983 ultrasounds performed between March 2003 and January 2006 for the prenatal diagnosis of @entity2914 . Medical records of each mother/ @entity1 pair were reviewed for demographic information, ultrasound findings, obstetric management, and outcomes. RESULTS: Nineteen fetuses were diagnosed with @entity2914 . Only one was lost to follow-up. Median gestational age at diagnosis was 28.4W (range 17.6-36.6). Fifteen cases (79%) were left sided, 3 (16%) were right-sided, and 1 (5%) was bilateral. Seven fetuses (39%) had additional abnormalities, the most common being a single umbilical artery. Ten @entity1 (52.6%) underwent amniocentesis for karyotype; none were aneuploid. Three @entity1 developed @entity2978 . All 18 @entity1 were liveborn. Seven @entity1 (39%) died shortly after birth, 6 (33%) underwent surgery with subsequent discharge, and 5 (28%) were transferred to another center. Three of these died after transfer. CONCLUSION: Prenatal diagnosis of @entity2914 portends a poor prognosis. Thirty-nine percent of @entity1 with this diagnosis (7/18) did not survive to undergo surgery or transfer to another facility and overall mortality was 56% (10/18). Targeted ultrasonography, extensive counseling of parents, and delivery at a tertiary care center is recommended.
