Markers of @entity32 and fibrinolysis in relation to outcome after surgery for @entity890 . A prospective study on 177 XXXX .

@entity1 @entity32 @entity1851 @entity2002 @entity2289 @entity615 @entity13549 @entity158 @entity717 @entity890
PURPOSE: The role of @entity32 and fibrinolysis for the development of @entity615 and @entity13549 has been discussed. The aim of this study was to assess the relationship between markers of @entity32 and fibrinolysis, to predict the outcome after surgery for @entity890 . METHODS: 177 @entity1 were recruited. High sensitive @entity1851 (hsCRP), @entity2289 ( @entity2289 ), @entity2002 , and D-dimer were analyzed preoperatively. Visual analogue scale (VAS) for back and @entity158 , @entity717 Index (ODI), and EuroQol 5 Dimensions (EQ-5D) were assessed preoperatively and at 6  weeks, 6-, 12-, and 24-  months postoperatively. Dichotomization was made at the median for the laboratory analyses, and between the worst quartile and the other three quartiles for the outcome variables. Logistic regression was used to determine the odds ratios (OR) and 95  % confidence intervals (CI). RESULTS: The associations between @entity2289 and outcome seemed to be most prominent at the 6 and 12-month follow-up. When being in the upper half of @entity2289 , the OR for being in the worst quartile of @entity615 12  months postoperatively was 3.33 (1.56-7.10). The corresponding OR for VAS @entity158 was 2.46 (1.18-5.10), for ODI 2.83 (1.35-5.94) and for EQ-5D 2.73 (1.30-5.75). The OR for hsCRP was 2.10 (1.03-4.29) for being in the worst quartile of @entity615 . @entity2002 or D-dimer was not associated with any outcome variable. CONCLUSIONS: High @entity2289 , a marker of fibrinolysis, was fairly consistently associated with poor outcome, while hsCRP, @entity2002 , and D-dimer were not.
