Cranial base characteristics in anteroposterior XXXX : A meta-analysis.

@entity1 @entity3233 @entity3232 @entity91 @entity17431
OBJECTIVE:     To investigate cranial base characteristics in @entity3232 with @entity91 . MATERIALS AND METHODS:     An electronic search was performed in PubMed, Embase, Web of Science, and the Cochrane Library. A fixed- or random-effect model was applied to calculate weighted mean difference with 95% confidence intervals (CIs) according to statistical heterogeneity. Outcome measures were anterior, posterior, and total cranial base length and cranial base angle. Sensitivity analysis and publication bias were conducted. RESULTS:     Twenty studies that together included 1121 Class I, 1051 Class II, and 730 Class III cases qualified for the final analysis. @entity3233 demonstrated significantly reduced anterior (95% CI: -1.74, -0.53; P < .001 vs Class I; 95% CI: -3.30, -2.09; P < .001 vs Class II) and total cranial base length (95% CI: -3.33, -1.36; P < .001 vs Class I; 95% CI: -7.38, -4.05; P < .001 vs Class II). Further, Class II @entity1 showed significantly greater anterior and total cranial base length than did Class I @entity1 (95% CI: 0.51, 1.87; P < .001 for SN; 95% CI: 2.20, 3.30; P < .001 for NBa). Cranial base angle was significantly smaller in Class III than in Class I (95% CI: -3.14, -0.93; P < .001 for NSBa; 95% CI: -2.73, -0.68; P = .001 for NSAr) and @entity17431 (95% CI: -5.73, -1.06; P = .004 for NSBa; 95% CI: -6.11, -1.92; P < .001 for NSAr) and greater in Class II than in Class I @entity3232 (95% CI: 1.38, 2.38; P < .001 for NSBa). CONCLUSIONS:     This meta-analysis showed that anterior and total cranial base length and cranial base angle were significantly smaller in @entity3233 than in Class I and @entity17431 , and that they were greater in Class II subjects compared to controls.
