Chinese medicinal plants for advanced XXXX after conservative surgery: a prospective, multi-center and controlled trial.

@entity1 @entity75 @entity10925 @entity46 @entity8923
UNASSIGNED: The trial was to explore the effects of Chinese medicinal plants (CMP) treatment on the advanced @entity46 (stage III-IV) after conservative surgery. A prospective, multi-center and controlled trial was conducted from June 2012 to September 2013. Sixty-five post-operative @entity1 with advanced @entity46 (stage III-IV) after conservative surgery were included in the trial. They had undergone laparoscopic surgical excision of the @entity75 and the diagnosis of @entity46 was confirmed by pathological examination. The @entity1 received either CMP treatment or @entity10925 sustained-release depot treatment (as comparison) according to the willingness of the @entity1 . In the post-treatment follow-up visit at 6 and 12 months, the @entity1 were respectively undergone ultrasonic and gynecological examinations. The serum levels of cancer antigen 125 (CA-125) and @entity8923 ( @entity8923 ) were also detected in the post-treatment follow-up visit at 12 months. We found that in the post-treatment follow-up visit at 6 months, the recurrence rate of CMP group and comparison group was 1/31 (3.23%) and 1/34 (2.94%), respectively. In the post-treatment follow-up visit at 12 months, the recurrence rate of CMP group and comparison group was 5/31 (16.13%) and 6/34 (17.65%), respectively. There were no significant differences between the two groups (P>0.05). The serum levels of CA-125 and @entity8923 significantly decreased in both of the two groups (P<0.05) and no marked differences existed between them on the serum levels of @entity8923 (P>0.05). The serum CA-125 levels of CMP group were significantly lower than those of the comparison group (P<0.05). No adverse effect was reported in both of the two groups during the research and the follow-up period. It concluded that CMP showed promise in preventing the recurrence of stage III-IV @entity46 after conservative surgery, although the conclusion is somewhat limited due to the small size of the trial.
