Incidence and potential risk factors of XXXX among Tehranian adults.

@entity1 @entity28 @entity209
AIM: Evaluating the incidence of @entity28 and its risk factors among Tehranian adults. MATERIAL _ METHODS: In this population-based cohort, non-obese @entity1 , aged >= 20years, were followed for development of @entity28 (Body Mass Index (BMI) >= 30). Incidence density and cumulative incidence rates of @entity28 were calculated for each sex. Cox proportional hazard regression was used to determine the association of potential @entity28 risk factors including: age, BMI, @entity209 , waist circumference (WC), smoking, marital status, education, and physical activity. RESULT: A total of 7257 @entity1 (3536 @entity1 ) were followed for a median of 8years. At baseline, mean age, BMI and WC were 41.3  14.6years, 25.1  2.9kg/m(2) (24.9  3kg/m(2) @entity1 and 25.2  3kg/m(2) @entity1 ), and 84.8  9.8cm (87.06  9.2cm @entity1 and 82.6  9.9cm @entity1 ) respectively. During the follow-up, 1345 @entity1 (876 @entity1 ) developed @entity28 contributing to cumulative incidences of 31.3% (CI: 29.9%-32.7%), 38.1% (CI: 36.2%-40.1%), and 23.4% (CI: 21.6%-25.3%) for the whole population, @entity1 , and @entity1 , respectively. Corresponding incidence density rates per 1000 @entity1 -year were 25.9 (CI: 24.5-27.3), 33.67 (CI: 31.5-36.0), and 18.0 (CI: 16.5-19.7), respectively. Highest incidence rates were observed during their 40s and 20s for @entity1 and @entity1 , respectively. @entity1 with @entity209 , lower educational level, higher BMI and WC, were at higher risk of @entity28 development in both sexes. CONCLUSION: High incidence of @entity28 was observed among Tehranian adults with higher incidence of @entity28 in @entity1 . Different modifiable variables may act as risk factors for @entity28 development which should be targeted to control the epidemic of @entity28 .
