Swedish experience of two dose vaccination programme aiming at eliminating measles, mumps, and XXXX .

@entity1 @entity2462
In 1982 a two dose regimen was introduced in Sweden for the combined vaccination against measles, mumps, and @entity2462 of @entity1 aged 18 months and 12 years. Since 1977 about half of the preschool @entity1 were vaccinated against measles annually, and since 1974 about 80% of 12 year old @entity1 were vaccinated against @entity2462 . During the period 1982 to 1985 90-93% of the eligible age cohorts of 18 month old @entity1 and 88-91% of the 12 year old @entity1 were immunised with the new combined vaccine. A study in 1982 of about 140 18 month old @entity1 who were nearly all seronegative before vaccination showed that 96%, 92%, and 99% seroconverted against measles, mumps, and @entity2462 , respectively. A second study was carried out in 1983 of 247 12 year old @entity1 , of whom 11% lacked antibodies to measles, 27% to mumps, and 45% to @entity2462 . This showed seroconversion in 82% and 80% against measles and mumps, respectively, and all @entity1 seroconverted against @entity2462 . In the latest study in 1985 of 496 12 year olds 9% and 13% were seronegative against measles and mumps before vaccination, and 41% against @entity2462 . Of these, 88% seroconverted to measles and 80% to mumps, and all converted to @entity2462 when sera were tested by the haemolysis in gel method. After a neutralisation test against measles as well all @entity1 showed immunity to the disease. A low incidence of measles and declining figures for mumps and @entity2462 were reported in 1984 to 1986. An outbreak of @entity2462 during 1985 affected mainly @entity1 in age cohorts in which only the @entity1 had been vaccinated during the 1970s.
