Implementation of guidelines for XXXX control in kidney transplant recipients: results at a single center.

@entity1 @entity407 @entity8 @entity101 @entity6 @entity1007 @entity177 @entity413 @entity209 @entity204 @entity65
BACKGROUND: @entity65 is a leading cause of @entity204 among kidney transplant recipients. @entity209 increases the risk for cardiovascular events and decreases graft survival. Lately, guidelines for management of the @entity209 , primarily @entity101 , @entity6 ( @entity6 ) and @entity1007 have dramatically changed in an attempt to decrease @entity65 among kidney transplant recipients. In the present study we examined whether these guideline changes had impact on our management of post-transplantation @entity1 and the subsequent treatment outcomes for these diseases. METHODS: Data were obtained from kidney transplant clinic files from two follow-up (FU) periods-between 1994-1997 and between 2008-2011. Demographic data, monitoring and screening frequency for cardiovascular risk factors, immunosuppression regimen, treatment for @entity101 , @entity6 and @entity407 , treatment outcomes and graft function changes were compared between the two follow-up periods. RESULTS: There was a significant increase in the percentage of @entity1 undergoing transplantation due to @entity177 secondary to @entity6 and/or @entity101 . @entity1 monitoring and screening during the second FU period were less frequent, but more targeted, reflecting changes in clinic routines. Blood pressure was better controlled in the second FU period (p  <  0.01), as was @entity1007 (p  <  0.001). High fasting @entity413 levels were more prevalent among @entity1 in the second group (p  <  0.005), although more @entity1 received treatment for @entity6 (p  <  0.001). Significantly, fewer @entity1 experienced @entity8 during the second FU period (p  <  0.001). CONCLUSIONS: We found that guideline changes had impact on clinical practice, which translated to better control of the @entity209 . @entity6 control is challenging. Overall, stability of kidney function improved.
