[Native vitamin  D in dialysis XXXX .]

@entity1 @entity41910 @entity11648 @entity740 @entity79 @entity2742 @entity942 @entity454
UNASSIGNED: @entity740 is frequent and usually responsible of @entity79 . These abnormalities lead to increased morbidity and mortality. To become active, native vitamin  D needs a first hydroxylation in the liver, and a second one in the kidney. Next to its action on bone metabolism, vitamin  D also possesses pleiotropic actions on cardiovascular, immune and neurological systems as well as antineoplastic activities. @entity454 ( @entity454 ) is also associated with a decrease in vitamin  D activity by mechanisms including the increase of plasma phosphate concentration, secretion of @entity11648  and decrease in 1a-hydroxylase activity. The prevalence of 25  hydroxy- @entity41910 depends on the chosen cut-off value to define this lack. Currently it is well established that a @entity1 has to be substituted when 25  hydroxy-vitamin  D level is under 30  ng/mL. The use and monitoring of 1.25  hydroxy-vitamin  D is still not recommended in routine practice. The goals of vitamin  D treatment in case of @entity454 are to substitute the @entity942 or treat @entity2742 . Interest of native vitamin  D in first intention is now well demonstrated. This review article describes the vitamin  D metabolism and physiology and also the treatment for @entity41910 in @entity454 population.
