Markers for XXXX in @entity1 with @entity221 without source.

@entity1 @entity55 @entity1904 @entity2348 @entity693 @entity281 @entity582 @entity221 @entity293 @entity1851
OBJECTIVES: To compare the diagnostic properties of @entity1904 (PCT), @entity1851 ( @entity1851 ), total white blood cells count (WBC), absolute neutrophil count (ANC) and clinical evaluation to detect serious @entity2348 (SBI) in @entity1 with @entity221 without source. DESIGN: Prospective cohort study. SETTING: Paediatric emergency department of a tertiary care hospital. @entity1 : @entity1 aged 1-36 months with @entity221 and no identified source of @entity281 . INTERVENTION: Complete blood count, blood culture, urine analysis and culture. PCT and @entity1851 were also measured and SBI probability evaluated clinically with a visual analogue scale before disclosing tests results. Outcome measure Area under the curves (AUC) of the receiver operating characteristic curves. RESULTS: Among the 328 @entity1 included in the study, 54 (16%) were diagnosed with an SBI: 48 @entity293 , 4 @entity55 , 1 @entity693 and 1 @entity582 . The AUC were similar for PCT (0.82; 95% CI 0.77 to 0.86), @entity1851 (0.88; 95% CI 0.84 to 0.91), WBC (0.81; 95% CI 0.76 to 0.85) and ANC (0.80; 95% CI 0.75 to 0.84). The only statistically significant difference was between @entity1851 and ANC (/\ AUC 0.08; 95% CI 0.01 to 0.16). It is important to note that all the surrogate markers were statistically superior to the clinical evaluation that had an AUC of only 0.59 (95% CI 0.54 to 0.65). CONCLUSION: The study data demonstrate that @entity1851 , PCT, WBC and ANC had almost similar diagnostic properties and were superior to clinical evaluation in predicting SBI in @entity1 aged 1 month to 3 years.
