XXXX -induced pulmonary changes: HRCT findings.

@entity1 @entity3126 @entity55 @entity8995 @entity5930 @entity2415 @entity14303 @entity2072 @entity358 @entity887 @entity11283
OBJECTIVE: To evaluate HRCT scans of the chest in 22 @entity1 with @entity2072 -induced @entity358 . METHODS: We included @entity1 between 19 and 52 years of age. The HRCT scans were evaluated by two radiologists independently, discordant results being resolved by consensus. The inclusion criterion was an HRCT scan showing abnormalities that were temporally related to @entity2072 use, with no other apparent causal factors. RESULTS: In 8 @entity1 (36.4%), the clinical and tomographic findings were consistent with "crack lung", those cases being studied separately. The major HRCT findings in that subgroup of @entity1 included ground-glass opacities, in 100% of the cases; consolidations, in 50%; and the halo sign, in 25%. In 12.5% of the cases, smooth septal thickening, @entity2415 , centrilobular nodules, and the tree-in-bud pattern were identified. Among the remaining 14 @entity1 (63.6%), @entity11283 was identified in 3 cases, presenting as @entity14303 , pneumothorax, and hemopneumothorax, respectively. Talcosis, characterized as perihilar conglomerate masses, architectural distortion, and @entity2415 , was diagnosed in 3 @entity1 . Other patterns were found less frequently: organizing @entity55 and @entity2415 , in 2 @entity1 each; and @entity8995 , @entity887 , @entity5930 , and @entity3126 , in 1 @entity1 each. CONCLUSIONS: Pulmonary changes induced by @entity2072 use are varied and nonspecific. The diagnostic suspicion of @entity2072 -induced @entity358 depends, in most of the cases, on a careful drawing of correlations between clinical and radiological findings.
