Intraabdominal XXXX with divergent differentiation: clinicopathological findings and DNA ploidy.

@entity1 @entity981 @entity2283 @entity66 @entity5 @entity2269 @entity2277 @entity5501
Five cases of @entity2269 with divergent differentiation are reported. All @entity1 were of male sex. They were 10, 15, 20, 21, and 30 years of age at time of diagnosis, respectively. By light microscopy, the @entity5 consisted of small cells arranged in groups, nests, and clusters separated by a collagen-rich @entity2269 . Immunohistochemical studies revealed the coexpression of mesenchymal, epithelial, and neural markers. Notably, all @entity5 coexpressed @entity2277 , cytokeratin, and @entity2283 , the latter in a remarkable paranuclear dot-like fashion. In contrast to other authors, we did not find chromogranin. DNA image cytometry on four cases demonstrated two diploid and two aneuploid ( @entity981 ) cases. No correlation was found between ploidy and prognosis. One @entity1 died from disease, another died from @entity5501 after bone marrow transplantation, and the remaining @entity1 are alive, but have progressive @entity66 . Thus, our findings support the poor prognosis in this type of @entity5 .
