[Prevention of XXXX during spinal anesthesia for elective caesarean section: Coloading with HAE 130/0.4 vs normal saline solution].

@entity1 @entity6358 @entity390 @entity71809 @entity391 @entity10 @entity551
OBJECTIVE: The aim of this study was to compare the efficacy of HES 130/0.4 coloading compared to normal saline solution for prevention of @entity551 during spinal anesthesia for elective caesarean section. STUDY DESIGN: Prospective, randomized. @entity1 AND METHODS: One hundred and twenty ASA I and II @entity1 scheduled for elective caesarean section were recruited. @entity1 were randomized to receive either 500mL of HES 130/0.4 ( @entity71809 (  )) coloading (GroupV) or 500mL of normal saline solution coloading (GroupC). Spinal anesthesia technique and @entity6358 administration were standardized in both groups. The primary endpoint was the incidence of @entity551 during spinal anesthesia for elective caesarean section. RESULTS: @entity551 occurred in 43 @entity1 in group C and 24 @entity1 in group V (p=0.001). @entity6358 consumption was significantly lower in group V (P=0.005). @entity390 , @entity391 and @entity10 incidence was higher in group C (p=0.006). Apgar scores and umbilical blood gazes were comparable between groups. CONCLUSION: HES 130/0.4 coload was more effective than normal saline solution to prevent @entity551 following spinal anesthesia for elective cesarean section. HES 130/0.4 coload reduced the incidence, the duration of @entity551 , the need for ephedrine and the adverse maternal effects.
