Topical treatment of pediatric XXXX with burns: a practical guide.

@entity1 @entity3637 @entity4 @entity2737 @entity281 @entity4808 @entity3 @entity5154 @entity1217 @entity130
Over 440 000 @entity1 receive medical attention for @entity130 each year in the US. @entity2737 are a major source of morbidity and mortality in these @entity1 . Infected wounds not only heal more slowly, but also may lead to @entity281 . The factors that contribute to wound complications are both the size and depth of the wound. @entity4808 is usually categorized into first-degree (superficial, involving only the epidermis), second-degree (partial thickness, involving both epidermis and dermis), and third-degree (full thickness, through the epidermis, dermis, and into fat). Burns that will not heal within 2 weeks are at least second-degree and should generally be referred to a burn surgeon for possible excision and grafting, due to the increased risk of @entity281 and scarring. The burn wound is dynamic. Proper treatment minimizes the extent of the @entity130 , whereas improper treatment (lack of proper wound-care, @entity4 formation, lack of resuscitation) may actually increase the size and/or depth of the wound. Topical antimicrobial agents have been shown to decrease wound-related @entity281 and morbidity in burn wounds when used appropriately. The goal of topical antimicrobial therapy is to control microbial colonization, thus preventing development of @entity3 . A wide variety of agents are available for treatment of burn wounds, including ointments, creams, biological and nonbiological dressings. Topical antimicrobials of choice include @entity3637 , @entity5154 , @entity1217 and mafenide.
