XXXX : Perspective from a Canadian tertiary care centre.

@entity5 @entity6461 @entity957 @entity1
INTRODUCTION: @entity957 ( @entity6461 ) is rare in North America; however, the morbidity can be devastating. This analysis represents the first reported penile @entity5 experience at a tertiary care centre in Canada. METHODS: We carried out a retrospective review of all @entity1 who received care at our centre for penile @entity6461 from 2005 until the present time. Epidemiological and clinical data were collected for all @entity1 . Survival analysis was performed using Kaplan-Meier methods with log-rank test and Cox regression for univariate and multivariate analysis, respectively. RESULTS: We identified 42 @entity1 who were treated at our centre for penile @entity6461 . Of these, 29% underwent excisional biopsy, 38% had partial penectomy, and 33% had total penectomy. Five @entity1 with high-risk @entity5 underwent modified inguinal lymph node dissection (ILND), while 7 @entity1 had radical ILND for clinically palpable disease. Overall, the median @entity5 specific survival (CSS) was undefined, with a 60% survival at 102 months. However CSS was significantly correlated to pT stage, pN stage, and @entity5 grade. The median follow-up was 25 months (interquartile range: 11-48). CONCLUSION: These findings confirm the poor CSS of @entity1 with positive lymph nodes in penile @entity6461 . @entity1 with pN0 after ILND had a durable CSS. Risk factors for penile @entity6461 were confirmed as elevated body mass index, positive smoking history, and lack of circumcision. This first epidemiologic report on penile @entity6461 from a Canadian tertiary care centre should be expanded to other national centres.
