Impact of community-acquired XXXX on acquisition of @entity580 , length of stay, and mortality in adult @entity130 @entity1 .

@entity1 @entity281 @entity5046 @entity580 @entity130
The incidence of @entity5046 ( @entity5046 ) and how it relates to the incidence of @entity580 ( @entity580 ) in the adult @entity130 population is unknown. We evaluated this incidence and assessed the impact of age on morbidity and mortality. Prospective data were collected on @entity130 @entity1 admitted >48 h over a 2-year period. Each @entity1 was screened for @entity281 by an infectious disease specialist. The Centers for Disease Control and Prevention (CDC) guidelines were used to diagnose @entity281 . Of the 2,645 @entity1 admitted, 86% were <65 years of age and 14% were > or =65 years of age. There was not a significant difference in Injury Severity Score (ISS) between the two groups. A total of 201 (8.8%) of the younger @entity1 were diagnosed with @entity5046 ; of these, 52.2% acquired a @entity580 . Additionally, 65 (17.4%) of the older @entity1 were diagnosed with a @entity5046 ; of these, 57% acquired a @entity580 . The combination of @entity5046 and @entity580 led to the most significant increases in intensive care (ILOS), hospital (HLOS) length of stay, and mortality. @entity1 with the @entity5046 had a significantly greater risk of obtaining an @entity580 in both age groups. The relative risk (RR) of an older @entity1 presenting with a @entity5046 was two times greater than in @entity1 <65 years old. The greatest relative risk of mortality (RRM) was demonstrated with the combination of @entity5046 and @entity580 , and age. However, once infected with both @entity5046 and @entity580 , younger @entity1 had a greater RRM (5.0 vs. 3.9) in the group-specific comparison. @entity5046 significantly increases the risk of @entity130 @entity1 acquiring an @entity580 . The combination of @entity5046 and @entity580 led to the most significant increases in HLOS, ILOS, and mortality. Increased age is associated with a significantly higher incidence of @entity5046 , ILOS, HLOS, and mortality. Once infected with both @entity5046 and @entity580 , younger @entity1 have a greater risk of mortality.
