Mechanical thrombectomy combined with recombinant @entity1456 thrombolysis in the venous sinus for the treatment of severe XXXX .

@entity1 @entity932 @entity548 @entity1456 @entity772 @entity1188 @entity50
UNASSIGNED: The aim of the present study was to assess the effectiveness and safety of endovascular interventional therapy, which is mechanical clot disruption combined with intrasinus thrombolytic therapy with recombinant @entity1456 (rt-PA), for severe @entity50 ( @entity50 ). The records of eight @entity1 with @entity50 confirmed by computed tomography, magnetic resonance imaging (MRI), magnetic resonance venography (MRV) and/or digital subtraction angiography were analyzed. Of the eight cases, the Glasgow @entity772 Scale (GCS) scores were between 4 and 9 with a mean value of 8.3  2.7. All the @entity1 had @entity1188 and two cases had @entity932 . Mechanical clot destruction combined with intrasinus thrombolytic therapy with rt-PA was performed under general anesthesia. Intravenous heparin therapy and intracerebral pressure control were applied during this period. One @entity1 succumbed and the other seven @entity1 showed good treatment efficacy. The GCS scores of the seven @entity1 reverted to 15 upon discharge from the Northern Jiangsu @entity1 's Hospital (Yangzhou, China). With regard to the modified Rankin score of the seven @entity1 three months following surgery, six @entity1 scored 0 and one @entity1 scored 1. MRI and MRV follow-up examinations were performed for 3-15 months. Complete recanalization of the criminal sinus, which refer to the sinus attributable to the @entity1188 or @entity548 , was observed in five cases and partial recanalization was observed in two cases. Symptoms were monitored for 3-24 months and no recurrence was observed. Therefore, mechanical thrombectomy combined with intrasinus thrombolytic therapy with rt-PA is safe and effective for @entity1 with severe @entity50 .
