Primary XXXX : A Case Report and Review of the Literature.

@entity1 @entity5 @entity4483 @entity3 @entity1282 @entity420 @entity320
BACKGROUND Primary @entity320 (PMME) is a rare @entity5 with a poor prognosis. It is often difficult to differentiate from non-epithelial @entity5 , and immunohistochemical staining may be needed to diagnose the condition. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The average survival rate after surgery is 34.5 months. At the time of diagnosis, 40-80% of cases have local regional lymph node @entity3 . CASE REPORT The case of a 67-year-old male @entity1 with PMME is reported. He presented with progressive @entity1282 . A computerized tomography was performed in which a polypoid mass was observed in the distal esophagus. It was originally suspected to be an @entity420 , but was subsequently correctly diagnosed by immunohistochemical staining with HMB-45 antibody and by the presence of @entity4483 protein. A subtotal esophagectomy was performed. CONCLUSIONS Very few cases of PMME have been reported in the literature and there is only limited clinical experience with this disease. Therefore, it is very difficult to establish clear criteria for clinical recognition of this type of @entity320 . Early histopathological confirmation of the character is essential for further treatment in case of confirmation of malignancy.
