FEV1 can predict SYNTAX score in XXXX with chronic obtructive pulmonary disease.

@entity1 @entity453 @entity1030
BACKGROUND: The SYNTAX score is an angiographic score which predicts @entity453 . It has been shown to be useful for decision making about percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) among @entity1 with @entity453 . Higher SYNTAX scores are indicative of more complex disease. @entity1030 ( @entity1030 ) is characterized by limitation of airflow. Meassurement of forced expiratory volume in 1 second (FEV1) in spirometry is used for diagnosis and determining the severity of the disease. AIM: The aim of this study was to evaluate the relationship between forced expiratory volume in 1 s (FEV1) and SYNTAX score in @entity1 wtih @entity1030 ( @entity1030 ). METHODS: Seventy eight @entity1 with a previous diagnosis of @entity1030 and 48 @entity1 without @entity1030 were enrolled. Spirometry and coronary angiography were performed in all @entity1 . SYNTAX score was calculated and compared between two groups. The correlation between FEV1 and SYNTAX score was analyzed. RESULTS: SYNTAX score was higher in @entity1 with @entity1030 than @entity1 without @entity1030 (23.22  12.10 vs 17.92  11.21 respectively, p=0.013). Multivariate analysis demonstrated that @entity1030 was an independently predictive for intermediate and high SYNTAX score (odds ratio 4.833; 95% confidence interval 2.228-10.485; p<0.001). Mean FEV1 (% predicted) was 64.7  11.4 and negatively correlated with SYNTAX score in @entity1030 group ( r= -0.266 and p=0.018). The receiver operating characteristic analysis yielded a cutoff value of 65.5 for the FEV1 to predict SYNTAX score >=  23, with sensivity and specifity being 78.6% and 70%, respectively. CONCLUSIONS: @entity1030 is a predictor of higher SYNTAX scores. FEV1 is associated with more severe and @entity453 .
