Mortality after XXXX : impact of gender and smoking status.

@entity1 @entity583 @entity204
We have shown previously that smoking causes a first @entity583 ( @entity583 ) to occur significantly more prematurely in @entity1 than in @entity1 . The aim of the study was to investigate mortality after @entity583 with special emphasis on the impact of smoking and gender. The study included 2,281 consecutive @entity1 (36.8% @entity1 ) who died or were discharged from a central hospital with a diagnosis of @entity583 from 1998 to 2005; the median follow-up of survivors was 7 years. @entity204 after @entity583 was adjusted for confounders. Mean age for @entity1 was 5.8 years older than for @entity1 (76.0 vs. 70.2 years) and @entity1 were less likely to have been smokers. In-hospital mortality for the first @entity583 was 8.9% for @entity1 and 13.3% for @entity1 , and total mortality rates for all indexed @entity583 after 7 years were 47% for @entity1 and 61% for @entity1 . Using Cox regression analysis, with all indexed MIs included, the after-discharge mortality for @entity1 was significantly lower than for @entity1 (hazard ratio 0.82; 95% confidence interval 0.70-0.96; P = 0.015). Compared with non-smokers, @entity1 who were smokers on admission had significantly increased seven-year mortality after discharge (hazard ratio 1.30; 95% confidence interval 1.03-1.63; P = 0.002). In conclusion, current smoking at the time of the indexed @entity583 was associated with increased mortality after 7 years follow-up. The smoking effect was independent of gender. Female gender was associated with a moderately lower risk of @entity204 during the same follow-up period.
