The effect of a @entity101 self-management intervention on @entity6 and XXXX control.

@entity1 @entity4051 @entity101 @entity6 @entity102 @entity165
BACKGROUND: Most @entity1 chronic disease self-management interventions target single-disease outcomes. We evaluated the effect of a tailored @entity101 self-management intervention on the unintended targets of glycosylated hemoglobin (HbA1c) and low-density lipoprotein @entity165 (LDL-C). METHODS: We evaluated @entity1 from the Veterans Study to Improve the Control of @entity101 , a 2-year randomized controlled trial. @entity1 received either a @entity101 self-management intervention delivered by a nurse over the telephone or usual care. Although the study focused on @entity101 self-management, we compared changes in HbA1c among a subgroup of 216 @entity1 with @entity6 and LDL-C among 528 @entity1 with measurements during the study period. Changes in these laboratory values over time were compared between the 2 treatment groups using linear mixed-effects models. RESULTS: For the @entity1 with @entity6 , the @entity101 self-management intervention resulted in a 0.46% reduction in @entity4051 c over 2 years compared with usual care (95% confidence interval, 0.04%-0.89%; P = .03). For LDL-C, there was a minimal 0.9 mg/dL between-group difference that was not statistically significant (95% confidence interval, -7.3-5.6 mg/dL; P = .79). CONCLUSIONS: There was a significant effect of the self-management intervention on the unintended target of HbA1c, but not LDL-C. @entity102 self-management interventions might have "spill-over" effects on @entity1 ' comorbid chronic conditions.
