T4 XXXX with infiltration of the thoracic aorta: is an operation reasonable?

@entity1 @entity0 @entity5 @entity1149 @entity2 @entity153 @entity3 @entity980
BACKGROUND: Only anecdotal reports about the results of combined resection of T4 @entity2 infiltrating the thoracic aorta exist. METHODS: Seven @entity1 (mean age, 57.5 years; range, 43 to 78 years) underwent a resection of the infiltrated segment of the thoracic aorta together with a left pneumonectomy (n = 6) or left upper lobectomy (n = 1). @entity5 were primary @entity1149 (T4N2 in 3 @entity1 , T4N1 in 2), one was a @entity3 of @entity0 , and one was @entity980 . RESULTS: No @entity1 died perioperatively. The 2 @entity1 with @entity980 and @entity3 of @entity0 died 2 and 7 months postoperatively. Of the 5 @entity1 with @entity153 , 3 died after 17, 26, and 27 months as a result of distant @entity3 . Two @entity1 are alive after 14 and 50 months without evidence of disease recurrence. One-year, 2-year, and 4-year survival rates for @entity1 with @entity153 were 100%, 75%, and 25%, respectively. CONCLUSIONS: Combined resection of the lung and thoracic aorta can be performed with low morbidity and mortality when offered to highly selected @entity1 . Adequate local control of @entity5 can be achieved for N1 and single-level N2 @entity1149 , but not for @entity5 with other histologies.
