Automated Perimetry and Visual Dysfunction in Blast-Related XXXX .

@entity1 @entity131 @entity227 @entity542 @entity4858 @entity1805 @entity2300
PURPOSE: To evaluate feasibility and results of automated perimetry in veterans with combat blast neurotrauma. DESIGN: Prospective, longitudinal, observational case series. @entity1 : Sixty-one @entity1 in a Veterans Affairs Polytrauma Center diagnosed with @entity131 ( @entity131 ) from combat blast exposure. METHODS: Study @entity1 underwent automated perimetry at baseline (median interval, 2 months after injury) (Humphrey Field Analyzer, Carl Zeiss Meditec, Dublin, CA, Swedish Interactive Threshold Algorithm 30-2 Standard or Fast), and 36 of them were followed up (median interval, 10 months after baseline). Presence of significant mean deviation and pattern standard deviation was determined for testing with reliability indices  <=20% for fixation loss, 15% for false-positives, and 33% for false-negatives. Test-retest stability of global visual field indices was assessed for tests with these cutoffs or with elevated fixation loss. Associations between global @entity227 and predictors were examined. MAIN OUTCOME MEASURES: Global visual field indices (mean deviation and pattern standard deviation). RESULTS: Among 61 study @entity1 (109 study eyes) with baseline testing, a field that met reliability cutoffs was obtained for 48 @entity1 (79%) and 78 eyes (72%). Fixation loss was found in 29% of eyes in initial testing. Nine study @entity1 (15%) demonstrated @entity1805 or @entity1805 , and an additional 36% had an abnormal global visual field index. Global indices were relatively stable at follow-up testing for tests meeting fixation-loss cutoffs and tests that did not. @entity227 due to post-chiasmal lesions were associated with moderate to severe @entity131 or penetrating @entity542 , but other @entity227 were prevalent across the range of mild to severe @entity131 . @entity4858 to the retina or choroid, poorer visual acuity, and @entity2300 were associated with @entity227 . @entity1 with @entity227 reported lower visual quality of life. CONCLUSIONS: Reliable automated perimetry can be accomplished in most @entity1 with @entity131 from combat blast exposure and reveals high rates of @entity227 , indicating that blast forces may significantly affect the eye and visual pathways.
