[Results of the surgical treatment of Conn's XXXX ].

@entity1 @entity1369 @entity101 @entity5 @entity1373 @entity972 @entity916 @entity652 @entity1368 @entity1482
During the last 10 years we operated on 69 Conn's @entity652 of which 59 were followed up for a mean period of 16 months (range: 3-96 months). Surgery cured the @entity101 (blood pressure less than 140/90) in 47 p. 100 of the @entity1 . Improved blood pressure (systolic: mean = 46 mmHg; range 0-135 mmHg and diastolic: mean = 25 mmHg; range 0-66 mmHg) was noted in another 47 p. 100 of @entity1 whereas no blood pressure change was noted in 3 @entity1 . Biological primary @entity1368 was found post-operatively in 2 of these 3 @entity1 and also in one whose @entity101 was improved. In this last @entity1 plus the three unimproved by surgery, small @entity5 (less than 10 mm) were found and co-existnt @entity1373 was found in the 2 @entity1 who had had an adrenalectomy. Fifty-one @entity1 were treated pre-operatively by @entity1482 (SP) alone (3.2 +/- 1.3 mg/kg) for a mean period of 6.8 weeks (range: 3 to 20 weeks). Only 2 of the 24 @entity1 controlled by SP were not cured by surgery and one of them had persistnt primary @entity1368 . Conversely, 3 of the 27 uncontrolled by SP were cured post-operatively, and these exceptions could be due to the weak dose of SP (n = 2) and an observance problem (n = 1). @entity1 cured by surgery had shorter duration of @entity101 (4.3 +/- 3.0 years vs 10.1 +/- 8.1; p less than 0.01) and lower diastolic pressure (111 +/- 14 mmHg vs 121 +/- 12; p less than 0.01) than uncured @entity1 . No significant difference between these two groups was observed with respect to systolic pressure, age, sex, plasma @entity972 , plasma @entity916 activity and plasma @entity1369 levels.(ABSTRACT TRUNCATED AT 250 WORDS)
