Primary cutaneous anaplastic large cell lymphoma (pcALCL) belongs to the primary cutaneous CD30+ T cell lymphoproliferative disorders.(1) Systemic involvement is relatively rare and rather confined to the regional lymph nodes.(1) We describe a patient with recurrent pcALCL and diffuse lung manifestation which spontaneously regressed after one SARS-CoV-2 vaccination. We report a 57-year-old male patient with a 10-year history of biopsy-proven (CD30+, CD3+, CD4+, ALK-, clonal T cell receptor gamma chain rearrangement) pcALCL with frequent local relapses predominantly affecting his scalp and neck.