In recent months, the presence of an emerging disease of infectious etiology has paralyzed everyone, already being a public health problem due to its high rate of infection, a life-threatening disease. The WHO has named it COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV2). New studies provide information of the role of the environment in COVID-19 transmission process, mortality related to this infectious disease and the impact on human health. The following review aims to analyze information on the implications of COVID-19 infection on human health and the impact of its presence on the environment, from its transmission capacity and the role of air pollutants and climatological factors to reducing the air pollution during confinement. Likewise, it provides a vision of the impact on the environment and human health of exposure to disinfectants and the presence of COVID-19 in wastewater, among other actions.