Some portion of National Highway 220 (NH220) passes through Tiruvalla. SH 07 and SH 08 are the two major State highways providing connectivity to other towns and districts. SH 07, also known as T. K. Road, passes only through Pathanamthitta. SH 08 also known as Main Eastern Highway, is the second longest state highway of Kerala. It connects the townships of Punalur in Kollam district and Muvattupuzha in Ernakulam district. The Kerala Public Work Department (P.W.D) maintains the all the roads in the district, including the village roads. As of 2005, the P.W.D. maintains about of road in the district.

There is a good connectivity of State transport, K.S.R.T.C., on the T.K. Road. However, on other roads and especially towards the eastern side, the State transport service is less frequent. Here, private bus operators facilitate the transportation needs. The K.S.R.T.C. has three major depots in the district. From Pathanamthitta, there are Inter State Services to Coimbatore and Tenkasi.
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